Experiment set8IT024 for Pseudomonas fluorescens FW300-N2E2

Compare to:

Cytosine nitrogen source

200 most detrimental genes:

  gene name fitness t score description  
Pf6N2E2_2406 +2.6 18.4 Periplasmic binding protein compare
Pf6N2E2_1674 +2.5 12.4 Hydroxymethylglutaryl-CoA synthase (EC 2.3.3.10) compare
Pf6N2E2_1675 +2.4 15.5 Lipid carrier protein or keto acyl-CoA thiolase Ltp3 (EC 2.3.1.16) compare
Pf6N2E2_2175 +1.6 4.9 Transcriptional regulator, RpiR family compare
Pf6N2E2_3871 +1.5 11.6 FIG00553872: hypothetical protein compare
Pf6N2E2_923 +1.5 3.0 Haloacid dehalogenase, type II (EC 3.8.1.2) compare
Pf6N2E2_3134 +1.5 1.9 hypothetical protein compare
Pf6N2E2_1677 +1.5 7.8 Chalcone synthase (EC 2.3.1.74) compare
Pf6N2E2_2284 +1.4 2.0 Cell division inhibitor-related protein compare
Pf6N2E2_1824 +1.3 3.0 hypothetical protein compare
Pf6N2E2_2178 +1.2 6.2 FIG00960144: hypothetical protein compare
Pf6N2E2_1617 +1.2 1.7 COG2199: FOG: GGDEF domain compare
Pf6N2E2_3037 +1.2 8.6 RNA polymerase sigma factor RpoS compare
Pf6N2E2_2057 +1.1 7.9 Phosphatidylserine/phosphatidylglycerophosphate/ cardiolipi n synthases and related enzymes compare
Pf6N2E2_1678 +1.1 8.2 Major facilitator family transporter compare
Pf6N2E2_1676 +1.1 3.3 conserved protein associated with acetyl-CoA C-acyltransferase compare
Pf6N2E2_3868 +1.0 7.0 Transcriptional regulator, LysR family compare
Pf6N2E2_1502 +1.0 1.7 Two-component system regulatory protein compare
Pf6N2E2_4747 +1.0 3.6 Transmembrane sensor compare
Pf6N2E2_2578 +1.0 2.0 Flagellar biosynthesis protein FliR compare
Pf6N2E2_5862 +0.9 1.8 Lipoprotein, putative compare
Pf6N2E2_5345 +0.9 6.2 LppC putative lipoprotein compare
Pf6N2E2_4548 +0.9 2.0 hypothetical protein compare
Pf6N2E2_2561 +0.9 2.7 FIG00955434: hypothetical protein compare
Pf6N2E2_180 +0.9 3.8 Transcriptional regulator, MerR family compare
Pf6N2E2_3088 +0.8 1.8 hypothetical protein compare
Pf6N2E2_1412 +0.8 2.6 hypothetical protein compare
Pf6N2E2_546 +0.8 1.6 FIG00966904: hypothetical protein compare
Pf6N2E2_338 +0.8 2.0 Transcriptional regulator, AraC family compare
Pf6N2E2_2425 +0.8 2.1 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
Pf6N2E2_2300 +0.8 1.8 LSU rRNA 2'-O-methyl-C2498 methyltransferase RlmM compare
Pf6N2E2_1504 +0.8 2.2 putative 2-pyrone-4,6-dicarboxylic acid hydrolase compare
Pf6N2E2_522 +0.8 3.2 Inositol transport system sugar-binding protein compare
Pf6N2E2_2592 +0.8 3.7 Flagellar motor switch protein FliG compare
Pf6N2E2_4743 +0.8 1.1 hypothetical protein compare
Pf6N2E2_5694 +0.8 3.5 Flagellar basal-body rod protein FlgB compare
Pf6N2E2_5252 +0.8 1.3 FIG00956396: hypothetical protein compare
Pf6N2E2_5207 +0.8 1.8 hypothetical protein compare
Pf6N2E2_3219 +0.7 1.4 hypothetical protein compare
Pf6N2E2_4710 +0.7 2.1 hypothetical protein compare
Pf6N2E2_5877 +0.7 1.4 Phosphohistidine phosphatase SixA compare
Pf6N2E2_3708 +0.7 4.5 predicted biotin regulatory protein BioR (GntR family) compare
Pf6N2E2_1666 +0.7 2.7 Transcriptional regulator, LysR family compare
Pf6N2E2_5609 +0.7 3.5 DNA-binding response regulator ColR compare
Pf6N2E2_1313 +0.7 1.3 2-oxo-hepta-3-ene-1,7-dioic acid hydratase (EC 4.2.-.-) compare
Pf6N2E2_2017 +0.7 1.2 DNA-binding protein compare
Pf6N2E2_405 +0.7 1.5 hypothetical protein compare
Pf6N2E2_3761 +0.7 6.2 Multimodular transpeptidase-transglycosylase (EC 2.4.1.129) (EC 3.4.-.-) compare
Pf6N2E2_1747 +0.7 1.6 3-oxoacyl-[acyl-carrier protein] reductase (EC 1.1.1.100) compare
Pf6N2E2_1596 +0.7 1.2 Periplasmic nitrate reductase component NapD compare
Pf6N2E2_2675 +0.7 0.7 ATP-dependent RNA helicase SrmB compare
Pf6N2E2_3588 +0.7 2.3 hypothetical protein compare
Pf6N2E2_1074 +0.7 1.2 FIG00953356: hypothetical protein compare
Pf6N2E2_2487 +0.7 0.9 FIG00956090: hypothetical protein compare
Pf6N2E2_4317 +0.7 2.4 FIG00964469: hypothetical protein compare
Pf6N2E2_5842 +0.7 2.7 Transcriptional regulator, TetR family compare
Pf6N2E2_6059 +0.7 2.1 FIG008443: hypothetical protein compare
Pf6N2E2_3978 +0.7 5.2 Type I secretion system, membrane fusion protein LapC compare
Pf6N2E2_4624 +0.7 0.8 Phosphoribosyl-dephospho-CoA transferase (EC 2.7.7.-) compare
Pf6N2E2_5086 +0.7 1.1 hypothetical protein compare
Pf6N2E2_6029 +0.6 2.0 hypothetical protein compare
Pf6N2E2_605 +0.6 1.3 FIG002465: BNR repeat protein compare
Pf6N2E2_1162 +0.6 1.1 Transmembrane amino acid efflux protein compare
Pf6N2E2_2984 +0.6 1.4 LysR family transcriptional regulator PA3398 compare
Pf6N2E2_5757 +0.6 2.8 hypothetical protein compare
Pf6N2E2_399 +0.6 1.8 Iron siderophore sensor protein compare
Pf6N2E2_2587 +0.6 4.6 Serine phosphatase RsbU, regulator of sigma subunit compare
Pf6N2E2_2583 +0.6 3.2 Flagellar motor switch protein FliM compare
Pf6N2E2_2350 +0.6 2.3 Oxygen-regulated invasion protein OrgB compare
Pf6N2E2_5610 +0.6 3.7 two-component system sensor protein compare
Pf6N2E2_5262 +0.6 1.1 FKBP-type peptidyl-prolyl cis-trans isomerase SlyD (EC 5.2.1.8) compare
Pf6N2E2_5081 +0.6 1.2 hypothetical protein compare
Pf6N2E2_3179 +0.6 1.7 FIG021952: putative membrane protein compare
Pf6N2E2_5902 +0.6 2.2 hypothetical protein compare
Pf6N2E2_3271 +0.6 1.6 Phosphocarrier protein, nitrogen regulation associated compare
Pf6N2E2_5874 +0.6 5.1 TonB-dependent receptor; Outer membrane receptor for ferrienterochelin and colicins compare
Pf6N2E2_2278 +0.6 4.8 Transcription-repair coupling factor compare
Pf6N2E2_2246 +0.6 2.2 Arabinose efflux permease compare
Pf6N2E2_3980 +0.6 4.5 Type I secretion system, outer membrane component LapE compare
Pf6N2E2_1885 +0.6 2.1 Transcriptional regulator, AraC family compare
Pf6N2E2_1792 +0.6 2.1 Hydroxypyruvate isomerase (EC 5.3.1.22) compare
Pf6N2E2_2636 +0.6 1.8 FIG027190: Putative transmembrane protein compare
Pf6N2E2_4332 +0.6 2.3 hypothetical protein compare
Pf6N2E2_2509 +0.6 1.5 UDP-glucose 4-epimerase (EC 5.1.3.2) compare
Pf6N2E2_3338 +0.6 0.9 1-phosphofructokinase (EC 2.7.1.56) compare
Pf6N2E2_1755 +0.6 2.5 2-Oxobutyrate oxidase, putative compare
Pf6N2E2_2589 +0.6 2.6 Flagellar protein FliJ compare
Pf6N2E2_434 +0.6 1.5 hypothetical protein compare
Pf6N2E2_4541 +0.6 1.0 hypothetical protein compare
Pf6N2E2_482 +0.6 1.6 Transcriptional regulator BkdR of isoleucine and valine catabolism operon compare
Pf6N2E2_4969 +0.6 0.9 hypothetical protein compare
Pf6N2E2_865 +0.6 0.7 Fumarylacetoacetate hydrolase family protein compare
Pf6N2E2_4990 +0.6 1.3 Uncharacterized protein, similar to the N-terminal domain of Lon protease compare
Pf6N2E2_3498 +0.6 2.0 FIG00953349: hypothetical protein compare
Pf6N2E2_2682 +0.6 1.9 Transcriptional regulator, LysR family compare
Pf6N2E2_1095 +0.6 1.5 Opine oxidase subunit C compare
Pf6N2E2_3658 +0.6 3.3 Lipid A core - O-antigen ligase and related enzymes compare
Pf6N2E2_755 +0.6 3.9 UPF0141 membrane protein YijP possibly required for phosphoethanolamine modification of lipopolysaccharide compare
Pf6N2E2_3293 +0.6 1.7 4-carboxymuconolactone decarboxylase (EC 4.1.1.44) compare
Pf6N2E2_5967 +0.6 1.7 L-arabinose 1-dehydrogenase / D-galactose 1-dehydrogenase (EC 1.1.1.46; EC 1.1.1.48) (from data) compare
Pf6N2E2_2173 +0.6 3.7 Precorrin-6A synthase (EC 2.1.1.152) compare
Pf6N2E2_1078 +0.6 3.5 Glycogen synthase, ADP-glucose transglucosylase (EC 2.4.1.21) compare
Pf6N2E2_1215 +0.6 1.7 probable membrane protein YPO2362 compare
Pf6N2E2_3568 +0.5 1.6 Unsaturated fatty acid biosythesis repressor FabR, TetR family compare
Pf6N2E2_4334 +0.5 3.4 Uncharacterized protein ImpC compare
Pf6N2E2_2477 +0.5 1.4 ABC transporter ATP-binding protein YvcR compare
Pf6N2E2_1236 +0.5 1.2 Transcriptional regulator, LysR family compare
Pf6N2E2_3979 +0.5 4.2 Type I secretion system ATPase, LssB family LapB compare
Pf6N2E2_4551 +0.5 1.3 hypothetical protein compare
Pf6N2E2_1584 +0.5 1.5 Transcriptional regulator, MarR family / Acetyltransferase (GNAT) compare
Pf6N2E2_1607 +0.5 2.1 Exopolyphosphatase (EC 3.6.1.11) compare
Pf6N2E2_969 +0.5 2.1 Putative uncharacterized protein STY4534 (Putative uncharacterized protein) compare
Pf6N2E2_4206 +0.5 0.7 Chromosome (plasmid) partitioning protein ParB compare
Pf6N2E2_5768 +0.5 2.0 DNA recombination-dependent growth factor C compare
Pf6N2E2_1099 +0.5 1.1 Hypothetical protein GlcG in glycolate utilization operon compare
Pf6N2E2_1180 +0.5 2.4 FOG: HEAT repeat compare
Pf6N2E2_5917 +0.5 2.4 Type II/IV secretion system protein TadC, associated with Flp pilus assembly compare
Pf6N2E2_1671 +0.5 1.6 Transcriptional regulator, TetR family compare
Pf6N2E2_762 +0.5 3.0 FIG00960186: hypothetical protein compare
Pf6N2E2_3122 +0.5 1.3 Chemotaxis signal transduction protein compare
Pf6N2E2_510 +0.5 3.6 Predicted transcriptional regulator of the myo-inositol catabolic operon compare
Pf6N2E2_3737 +0.5 1.4 General secretion pathway protein M compare
Pf6N2E2_3625 +0.5 3.6 Flagellar motor rotation protein MotA compare
Pf6N2E2_4052 +0.5 1.0 FIG00955481: hypothetical protein compare
Pf6N2E2_3108 +0.5 1.9 FIG00953405: hypothetical protein compare
Pf6N2E2_945 +0.5 1.5 Transcriptional regulator, TetR family compare
Pf6N2E2_2573 +0.5 2.8 RNA polymerase sigma factor for flagellar operon compare
Pf6N2E2_2440 +0.5 0.8 Free methionine-(R)-sulfoxide reductase, contains GAF domain compare
Pf6N2E2_5697 +0.5 4.1 Flagellar hook protein FlgE compare
Pf6N2E2_1905 +0.5 1.7 Isoquinoline 1-oxidoreductase alpha subunit (EC 1.3.99.16) compare
Pf6N2E2_1484 +0.5 2.0 N-acetyl-gamma-glutamyl-phosphate reductase (EC 1.2.1.38) compare
Pf6N2E2_1197 +0.5 2.9 Octaprenyl diphosphate synthase (EC 2.5.1.90) / Dimethylallyltransferase (EC 2.5.1.1) / (2E,6E)-farnesyl diphosphate synthase (EC 2.5.1.10) / Geranylgeranyl diphosphate synthase (EC 2.5.1.29) compare
Pf6N2E2_4691 +0.5 1.4 hypothetical protein compare
Pf6N2E2_2262 +0.5 0.9 Phosphonoacetaldehyde phosphonohydrolase-related protein compare
Pf6N2E2_1463 +0.5 0.9 Isochorismate pyruvate-lyase (EC 4.-.-.-) compare
Pf6N2E2_6007 +0.5 1.4 Glutathione S-transferase (EC 2.5.1.18) compare
Pf6N2E2_1176 +0.5 1.1 Mll2356 protein compare
Pf6N2E2_3033 +0.5 1.0 hypothetical protein compare
Pf6N2E2_1796 +0.5 1.8 Glycine cleavage system transcriptional activator GcvA compare
Pf6N2E2_2579 +0.5 2.6 Flagellar biosynthesis protein FliQ compare
Pf6N2E2_3981 +0.5 4.4 T1SS secreted agglutinin RTX compare
Pf6N2E2_1600 +0.5 2.4 diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s) compare
Pf6N2E2_704 +0.5 1.4 Cytochrome c551/c552 compare
Pf6N2E2_3094 +0.5 2.1 SAM-dependent methyltransferase (EC 2.1.1.-) compare
Pf6N2E2_4426 +0.5 2.3 DNA-binding protein inhibitor Id-2-related protein compare
Pf6N2E2_3698 +0.5 1.7 Nicotinamidase family protein YcaC compare
Pf6N2E2_1557 +0.5 2.3 hypothetical protein compare
Pf6N2E2_1462 +0.5 2.1 Nicotinamidase/isochorismatase family protein compare
Pf6N2E2_4339 +0.5 3.5 Uncharacterized protein ImpJ/VasE compare
Pf6N2E2_4337 +0.5 3.9 Uncharacterized protein ImpI/VasC compare
Pf6N2E2_1199 +0.5 1.0 hypothetical protein compare
Pf6N2E2_2222 +0.5 1.9 Murein-DD-endopeptidase (EC 3.4.99.-) compare
Pf6N2E2_2584 +0.5 2.9 Flagellar biosynthesis protein FliL compare
Pf6N2E2_2 +0.5 1.7 FIG057993:Thioesterase involved in non-ribosomal peptide biosynthesis compare
Pf6N2E2_5691 +0.5 3.5 Flagellar basal-body P-ring formation protein FlgA compare
Pf6N2E2_3982 +0.5 1.7 Tryptophan synthase beta chain like (EC 4.2.1.20) compare
Pf6N2E2_1485 +0.5 2.2 Transcriptional regulator compare
Pf6N2E2_2910 +0.5 1.7 Carbamate kinase (EC 2.7.2.2) compare
Pf6N2E2_3727 +0.5 1.8 3-hydroxydecanoyl-[ACP] dehydratase (EC 4.2.1.60) compare
Pf6N2E2_4773 +0.5 0.7 Coenzyme PQQ synthesis protein D compare
Pf6N2E2_1958 +0.5 1.2 Predicted dinucleotide-binding enzymes compare
Pf6N2E2_4305 +0.5 0.7 FIG00959590: hypothetical protein compare
Pf6N2E2_3828 +0.5 1.8 tRNA (cytidine(34)-2'-O)-methyltransferase (EC 2.1.1.207) compare
Pf6N2E2_84 +0.5 1.0 hypothetical protein compare
Pf6N2E2_1195 +0.5 2.0 hypothetical protein compare
Pf6N2E2_5485 +0.5 1.7 Large exoproteins involved in heme utilization or adhesion compare
Pf6N2E2_1022 +0.5 1.3 Butyryl-CoA dehydrogenase (EC 1.3.99.2) compare
Pf6N2E2_1567 +0.5 1.9 FIG00964846: hypothetical protein compare
Pf6N2E2_3494 +0.5 1.9 Acyl dehydratase compare
Pf6N2E2_2985 +0.5 1.3 Diacylglycerol kinase (EC 2.7.1.107) compare
Pf6N2E2_5280 +0.5 2.1 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases compare
Pf6N2E2_1670 +0.5 1.5 conserved membrane protein compare
Pf6N2E2_2786 +0.5 2.6 (R)-3-hydroxydecanoyl-ACP:CoA transacylase PhaG (3-hydroxyacyl-CoA-acyl carrier protein transferase) (EC 2.4.1.-) compare
Pf6N2E2_5910 +0.5 1.7 Flp pilus assembly protein RcpC/CpaB compare
Pf6N2E2_4579 +0.5 0.8 Ribosomal RNA small subunit methyltransferase D (EC 2.1.1.-) compare
Pf6N2E2_649 +0.5 1.3 General secretion pathway protein L compare
Pf6N2E2_5576 +0.5 2.0 Cys-tRNA(Pro) deacylase YbaK compare
Pf6N2E2_6089 +0.4 2.2 ThiJ/PfpI family protein compare
Pf6N2E2_5467 +0.4 2.3 Response regulator compare
Pf6N2E2_4993 +0.4 1.5 Gamma-glutamyl phosphate reductase (EC 1.2.1.41) compare
Pf6N2E2_4057 +0.4 0.6 lipoprotein, putative compare
Pf6N2E2_1173 +0.4 1.1 hypothetical protein compare
Pf6N2E2_3875 +0.4 1.0 FIG00953324: hypothetical protein compare
Pf6N2E2_3397 +0.4 1.3 Phage protein compare
Pf6N2E2_3791 +0.4 3.2 Glucans biosynthesis glucosyltransferase H (EC 2.4.1.-) compare
Pf6N2E2_4719 +0.4 2.2 Sarcosine oxidase delta subunit (EC 1.5.3.1) compare
Pf6N2E2_3270 +0.4 1.7 Hypothetical ATP-binding protein UPF0042, contains P-loop compare
Pf6N2E2_6052 +0.4 2.3 Hydantoin racemase (EC 5.1.99.-) compare
Pf6N2E2_3864 +0.4 1.1 hypothetical protein compare
Pf6N2E2_3105 +0.4 1.9 hypothetical protein compare
Pf6N2E2_1679 +0.4 2.3 SUGAR TRANSPORTER compare
Pf6N2E2_5869 +0.4 1.6 Helicase subunit of the DNA excision repair complex compare
Pf6N2E2_2755 +0.4 0.7 Sigma factor RpoE negative regulatory protein RseA compare
Pf6N2E2_2999 +0.4 0.9 probable tail fiber assembly protein compare
Pf6N2E2_5229 +0.4 2.2 Transcriptional regulator, MerR family, associated with photolyase compare
Pf6N2E2_2139 +0.4 0.7 Paraquat-inducible protein A compare
Pf6N2E2_421 +0.4 1.7 Methyl-accepting chemotaxis protein compare
Pf6N2E2_571 +0.4 1.8 ADA regulatory protein / Methylated-DNA--protein-cysteine methyltransferase (EC 2.1.1.63) compare
Pf6N2E2_2108 +0.4 2.5 hypothetical protein compare
Pf6N2E2_487 +0.4 2.4 TRAP-type C4-dicarboxylate transport system, periplasmic component compare


Specific Phenotypes

For 18 genes in this experiment

For nitrogen source Cytosine in Pseudomonas fluorescens FW300-N2E2

For nitrogen source Cytosine across organisms