Experiment set8IT024 for Methanococcus maripaludis S2

Compare to:

Mc formate, casamino free, with 10mM L-Tyrosine

200 most detrimental genes:

  gene name fitness t score description  
MMP_RS03615 +2.0 16.1 4Fe-4S binding protein compare
MMP_RS03620 +1.7 11.6 hypothetical protein compare
MMP_RS01370 +1.4 6.6 acetate--CoA ligase family protein compare
MMP_RS04720 +1.3 3.8 DedA family protein compare
MMP_RS00520 +1.2 2.5 RNA polymerase Rpb4 family protein compare
MMP_RS04550 +1.1 7.1 S-layer protein compare
MMP_RS07820 +0.9 3.5 UPF0104 family protein compare
MMP_RS07875 +0.9 4.3 hypothetical protein compare
MMP_RS06525 +0.9 1.3 YciI family protein compare
MMP_RS08155 +0.8 4.1 hypothetical protein compare
MMP_RS01895 +0.8 6.7 flippase compare
MMP_RS06900 +0.8 2.1 coenzyme F420-reducing hydrogenase FrhD protein compare
MMP_RS07125 +0.8 2.6 coenzyme F420-reducing hydrogenase FrhD protein compare
MMP_RS07390 +0.8 2.1 cell division protein FtsZ compare
MMP_RS01875 +0.8 5.5 N-acetyltransferase compare
MMP_RS01885 +0.8 5.3 Gfo/Idh/MocA family oxidoreductase compare
MMP_RS06570 +0.8 3.2 DUF190 domain-containing protein compare
MMP_RS01960 +0.8 1.0 hypothetical protein compare
MMP_RS06395 +0.8 3.3 ThiF family adenylyltransferase compare
MMP_RS08455 +0.7 3.3 multiprotein bridging factor aMBF1 compare
MMP_RS01955 +0.7 2.6 hypothetical protein compare
MMP_RS03215 +0.7 4.7 MBL fold metallo-hydrolase compare
MMP_RS07115 +0.7 3.3 MBL fold metallo-hydrolase compare
MMP_RS01540 +0.7 2.3 DUF504 domain-containing protein compare
MMP_RS05355 +0.7 0.7 hypothetical protein compare
MMP_RS01775 +0.6 1.4 TIGR00297 family protein compare
MMP_RS08315 +0.6 2.6 S-methyl-5-thioribose-1-phosphate isomerase compare
MMP_RS05640 +0.6 3.6 UTP--glucose-1-phosphate uridylyltransferase GalU compare
MMP_RS03245 +0.6 3.4 DNA repair and recombination protein RadB compare
MMP_RS08775 +0.6 3.0 methanogenesis marker 9 domain-containing protein compare
MMP_RS01100 +0.6 1.3 ABC transporter ATP-binding protein compare
MMP_RS08705 +0.6 4.0 sulfopyruvate decarboxylase subunit beta compare
MMP_RS07890 +0.6 1.9 OB-fold nucleic acid binding domain-containing protein compare
MMP_RS07120 +0.6 3.7 coenzyme F420 hydrogenase subunit alpha compare
MMP_RS08090 +0.6 2.9 hypothetical protein compare
MMP_RS06575 +0.6 2.1 fluoride efflux transporter CrcB compare
MMP_RS01880 +0.6 3.1 DegT/DnrJ/EryC1/StrS family aminotransferase compare
MMP_RS04740 +0.6 2.8 DUF473 domain-containing protein compare
MMP_RS06745 +0.6 3.2 DUF2119 domain-containing protein compare
MMP_RS02675 +0.6 1.6 hypothetical protein compare
MMP_RS01910 +0.6 3.8 UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing) compare
MMP_RS08930 +0.6 0.7 hypothetical protein compare
MMP_RS00450 +0.6 1.2 4Fe-4S binding protein compare
MMP_RS07540 +0.6 1.9 CBS domain-containing protein compare
MMP_RS02310 +0.6 1.2 RimK-like ATPgrasp N-terminal domain-containing protein compare
MMP_RS06555 +0.6 2.1 cupin domain-containing protein compare
MMP_RS01525 +0.5 1.3 nucleoside-diphosphate kinase compare
MMP_RS01970 +0.5 4.3 TIGR04279 domain-containing protein compare
MMP_RS02595 +0.5 1.0 putative zinc-binding protein compare
MMP_RS02780 +0.5 3.8 hypothetical protein compare
MMP_RS01975 +0.5 4.4 hypothetical protein compare
MMP_RS01940 +0.5 2.3 MoxR family ATPase compare
MMP_RS01865 +0.5 1.0 GPR1/FUN34/YaaH family transporter compare
MMP_RS07130 +0.5 2.8 coenzyme F420 hydrogenase subunit gamma compare
MMP_RS07700 +0.5 3.7 DUF1188 domain-containing protein compare
MMP_RS00315 +0.5 2.0 Nif3-like dinuclear metal center hexameric protein compare
MMP_RS07915 +0.5 2.3 DUF4870 domain-containing protein compare
MMP_RS01620 +0.5 1.5 hypothetical protein compare
MMP_RS05980 +0.5 2.8 ferritin compare
MMP_RS01900 +0.5 4.0 hypothetical protein compare
MMP_RS04520 +0.5 1.3 nucleoside deaminase compare
MMP_RS08890 +0.5 4.0 glycosyltransferase family 4 protein compare
MMP_RS04850 +0.5 4.0 UPF0254 family protein compare
MMP_RS01930 +0.5 3.8 hypothetical protein compare
MMP_RS02475 +0.5 1.6 hypothetical protein compare
MMP_RS02790 +0.5 0.7 class III signal peptide-containing protein compare
MMP_RS01915 +0.5 3.8 DUF354 domain-containing protein compare
MMP_RS01920 +0.5 3.7 glycosyltransferase family 2 protein compare
MMP_RS01650 +0.5 0.5 sulfurtransferase TusA family protein compare
MMP_RS05970 +0.4 2.0 class II SORL domain-containing protein compare
MMP_RS07620 +0.4 1.3 energy-coupling factor ABC transporter substrate-binding protein compare
MMP_RS00945 +0.4 0.7 PadR family transcriptional regulator compare
MMP_RS06670 +0.4 2.0 glucose-6-phosphate isomerase compare
MMP_RS08470 +0.4 2.2 ATP-binding cassette domain-containing protein compare
MMP_RS06550 +0.4 2.8 AMP-binding protein compare
MMP_RS06965 +0.4 2.3 TIGR04014 family B12-binding domain/radical SAM domain-containing protein compare
MMP_RS01925 +0.4 3.4 DUF1616 domain-containing protein compare
MMP_RS01030 +0.4 1.9 MTAP family purine nucleoside phosphorylase compare
MMP_RS06585 +0.4 0.9 DMT family protein compare
MMP_RS00660 +0.4 2.4 alkaline phosphatase family protein compare
MMP_RS08500 +0.4 1.5 pyridoxal 5'-phosphate synthase glutaminase subunit PdxT compare
MMP_RS07695 +0.4 3.0 DUF3236 domain-containing protein compare
MMP_RS01685 +0.4 1.4 indolepyruvate oxidoreductase subunit beta compare
MMP_RS09050 +0.4 2.2 CAP domain-containing protein compare
MMP_RS01905 +0.4 3.3 glycosyltransferase compare
MMP_RS06480 +0.4 2.7 ABC transporter substrate-binding protein compare
MMP_RS06290 +0.4 1.9 DNA repair and recombination protein RadA compare
MMP_RS05275 +0.4 3.0 AI-2E family transporter compare
MMP_RS07895 +0.4 1.7 cytochrome c compare
MMP_RS01640 +0.4 2.3 2-oxoacid:acceptor oxidoreductase subunit alpha compare
MMP_RS03840 +0.4 1.9 hypothetical protein compare
MMP_RS08620 +0.4 2.2 flagellar accessory protein FlaH compare
MMP_RS05525 +0.4 2.0 calcium/sodium antiporter compare
MMP_RS02815 +0.4 1.0 hypothetical protein compare
MMP_RS06530 +0.4 1.6 bifunctional hexulose-6-phosphate synthase/ribonuclease regulator compare
MMP_RS03785 +0.4 1.5 cupin domain-containing protein compare
MMP_RS00635 +0.4 1.8 energy-coupling factor transporter transmembrane protein EcfT compare
MMP_RS08265 +0.4 1.7 rubrerythrin compare
MMP_RS06540 +0.4 1.1 3-methyl-2-oxobutanoate dehydrogenase subunit VorB compare
MMP_RS03765 +0.4 2.2 CopG family ribbon-helix-helix protein compare
MMP_RS00795 +0.4 1.9 formate dehydrogenase H subunit alpha selenocysteine-containing compare
MMP_RS00940 +0.4 2.3 daunorubicin resistance protein DrrA family ABC transporter ATP-binding protein compare
MMP_RS06435 +0.4 1.7 CBS domain-containing protein compare
MMP_RS02410 +0.4 1.2 ABC transporter substrate-binding protein compare
MMP_RS02875 +0.4 2.3 chorismate pyruvate-lyase family protein compare
MMP_RS05470 +0.4 2.5 DUF523 and DUF1722 domain-containing protein compare
MMP_RS08275 +0.4 1.6 hypothetical protein compare
MMP_RS06155 +0.4 1.3 DUF4186 domain-containing protein compare
MMP_RS06535 +0.4 1.3 2-oxoacid:acceptor oxidoreductase family protein compare
MMP_RS01580 +0.4 2.3 PQQ-binding-like beta-propeller repeat protein compare
MMP_RS05900 +0.4 1.7 tetratricopeptide repeat protein compare
MMP_RS02970 +0.4 2.2 hypothetical protein compare
MMP_RS04595 +0.4 1.7 hypothetical protein compare
MMP_RS00650 +0.3 2.1 ABC transporter ATP-binding protein compare
MMP_RS08640 +0.3 2.1 TIM barrel protein compare
MMP_RS01460 +0.3 1.1 hypothetical protein compare
MMP_RS00100 +0.3 2.2 tRNA pseudouridine(13) synthase TruD compare
MMP_RS06165 +0.3 2.3 ABC transporter permease compare
MMP_RS01950 +0.3 2.5 hypothetical protein compare
MMP_RS05150 +0.3 2.0 hypothetical protein compare
MMP_RS07970 +0.3 1.2 hypothetical protein compare
MMP_RS08235 +0.3 1.7 hypothetical protein compare
MMP_RS06335 +0.3 1.9 HAD family hydrolase compare
MMP_RS02895 +0.3 2.1 DHH family phosphoesterase compare
MMP_RS08175 +0.3 2.1 7-cyano-7-deazaguanine synthase compare
MMP_RS05990 +0.3 1.7 DsrE family protein compare
MMP_RS00675 +0.3 0.4 nitroreductase family protein compare
MMP_RS06000 +0.3 1.9 divalent-cation tolerance protein CutA compare
MMP_RS00725 +0.3 1.3 5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdC compare
MMP_RS01095 +0.3 1.3 iron ABC transporter permease compare
MMP_RS00770 +0.3 1.2 hypothetical protein compare
MMP_RS03280 +0.3 1.7 pyridoxamine 5'-phosphate oxidase family protein compare
MMP_RS02725 +0.3 1.5 molybdate ABC transporter permease subunit compare
MMP_RS00665 +0.3 1.3 hypothetical protein compare
MMP_RS07815 +0.3 0.5 DUF2120 domain-containing protein compare
MMP_RS00185 +0.3 2.0 potassium channel protein compare
MMP_RS06610 +0.3 1.0 DUF2334 domain-containing protein compare
MMP_RS06500 +0.3 1.6 ATP-binding protein compare
MMP_RS08555 +0.3 1.1 hypothetical protein compare
MMP_RS00880 +0.3 1.3 ribosome assembly RNA-binding protein YhbY compare
MMP_RS00085 +0.3 2.1 DNA cytosine methyltransferase compare
MMP_RS07925 +0.3 1.0 haloacid dehalogenase compare
MMP_RS02490 +0.3 1.2 hypothetical protein compare
MMP_RS03670 +0.3 0.8 DUF1890 domain-containing protein compare
MMP_RS05360 +0.3 1.5 hypothetical protein compare
MMP_RS01980 +0.3 2.1 trimeric intracellular cation channel family protein compare
MMP_RS00375 +0.3 1.8 ammonium transporter compare
MMP_RS07075 +0.3 1.1 phosphomannomutase/phosphoglucomutase compare
MMP_RS08160 +0.3 2.1 EamA family transporter compare
MMP_RS06520 +0.3 1.3 DUF1786 domain-containing protein compare
MMP_RS00385 +0.3 1.4 P-II family nitrogen regulator compare
MMP_RS04475 +0.3 1.7 nitrogen fixation compare
MMP_RS00955 +0.3 1.6 coenzyme gamma-F420-2:alpha-L-glutamate ligase compare
MMP_RS03150 +0.3 1.9 phosphoglycerate mutase compare
MMP_RS07680 +0.3 1.1 DUF366 family protein compare
MMP_RS08975 +0.3 1.3 hypothetical protein compare
MMP_RS06430 +0.3 1.7 6-carboxytetrahydropterin synthase QueD compare
MMP_RS00125 +0.3 0.5 DUF2798 domain-containing protein compare
MMP_RS02645 +0.3 2.1 ArsR family transcriptional regulator compare
MMP_RS00380 +0.3 1.3 P-II family nitrogen regulator compare
MMP_RS08260 +0.3 1.6 DUF99 family protein compare
MMP_RS00630 +0.3 1.4 ECF transporter S component compare
MMP_RS03910 +0.3 0.7 hypothetical protein compare
MMP_RS03870 +0.3 1.3 purine NTPase compare
MMP_RS01805 +0.3 0.8 NUDIX hydrolase compare
MMP_RS08485 +0.3 1.5 tungstate ABC transporter substrate-binding protein WtpA compare
MMP_RS02110 +0.3 0.5 hypothetical protein compare
MMP_RS06070 +0.3 1.7 iron ABC transporter substrate-binding protein compare
MMP_RS02835 +0.3 0.8 CGGC domain-containing protein compare
MMP_RS07805 +0.3 1.0 ABC transporter permease compare
MMP_RS00545 +0.3 1.1 XRE family transcriptional regulator compare
MMP_RS05770 +0.3 1.0 YkgJ family cysteine cluster protein compare
MMP_RS05580 +0.3 2.3 glycosyltransferase compare
MMP_RS02360 +0.3 1.8 hypothetical protein compare
MMP_RS04970 +0.3 2.0 F420-dependent thioredoxin reductase compare
MMP_RS06440 +0.2 1.7 CBS domain-containing protein compare
MMP_RS06150 +0.2 1.8 hypothetical protein compare
MMP_RS00155 +0.2 1.6 heavy metal-binding domain-containing protein compare
MMP_RS04515 +0.2 1.4 betaine/proline/choline family ABC transporter ATP-binding protein compare
MMP_RS06910 +0.2 1.4 RlmF-related methyltransferase compare
MMP_RS03890 +0.2 1.2 DUF2540 domain-containing protein compare
MMP_RS01060 +0.2 1.4 calcium/sodium antiporter compare
MMP_RS03065 +0.2 0.7 AzlC family ABC transporter permease compare
MMP_RS08310 +0.2 0.6 TMEM165/GDT1 family protein compare
MMP_RS06605 +0.2 1.3 DUF5814 domain-containing protein compare
MMP_RS01550 +0.2 1.5 DUF1624 domain-containing protein compare
MMP_RS07385 +0.2 0.7 protein translocase SEC61 complex subunit gamma compare
MMP_RS06765 +0.2 1.3 flap endonuclease-1 compare
MMP_RS05975 +0.2 0.4 hypothetical protein compare
MMP_RS02840 +0.2 1.4 DUF123 domain-containing protein compare
MMP_RS05720 +0.2 1.0 signal recognition particle subunit SRP19/SEC65 family protein compare
MMP_RS06365 +0.2 0.6 hypothetical protein compare
MMP_RS03010 +0.2 1.8 cupin domain-containing protein compare
MMP_RS00395 +0.2 0.4 MGMT family protein compare
MMP_RS03325 +0.2 1.7 hypothetical protein compare
MMP_RS02570 +0.2 1.9 cation:proton antiporter compare
MMP_RS07355 +0.2 0.3 transcription factor S compare
MMP_RS03990 +0.2 1.4 recombinase family protein compare
MMP_RS05905 +0.2 1.0 undecaprenyl-diphosphate phosphatase compare
MMP_RS08700 +0.2 1.7 hypothetical protein compare


Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in nutrient t1 experiments

For nutrient t1 L-tyrosine disodium salt across organisms