Experiment set8IT023 for Methanococcus maripaludis S2

Compare to:

Mc formate, casamino free, with 10mM L-Tyrosine

200 most important genes:

  gene name fitness t score description  
MMP_RS06355 -4.1 -3.9 molybdenum cofactor biosynthesis protein MoaE compare
MMP_RS05550 -4.0 -1.1 cation:proton antiporter compare
MMP_RS06350 -4.0 -11.5 HesA/MoeB/ThiF family protein compare
MMP_RS06680 -3.7 -19.8 Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain compare
MMP_RS03015 -3.7 -12.9 GTP 3' 8-cyclase MoaA compare
MMP_RS05515 -3.7 -13.7 cyclic pyranopterin monophosphate synthase MoaC compare
MMP_RS08165 -3.6 -5.2 phosphoglycerate dehydrogenase compare
MMP_RS01755 -3.6 -2.6 DUF2097 domain-containing protein compare
MMP_RS06685 -3.5 -16.7 formate dehydrogenase H subunit alpha selenocysteine-containing compare
MMP_RS05500 -3.4 -11.2 2-isopropylmalate synthase compare
MMP_RS06700 -3.3 -17.1 hypothetical protein compare
MMP_RS01020 -3.3 -2.1 3 4-dihydroxy-2-butanone-4-phosphate synthase compare
MMP_RS01175 -3.3 -5.2 triphosphoribosyl-dephospho-CoA synthase compare
MMP_RS07345 -3.3 -8.5 glycine synthesis protein GlyXL (from data) compare
MMP_RS07635 -3.2 -10.1 MogA/MoaB family molybdenum cofactor biosynthesis protein compare
MMP_RS03450 -3.1 -4.1 glycine synthesis protein GlyXS (from data) compare
MMP_RS06345 -3.0 -16.2 formate dehydrogenase accessory sulfurtransferase FdhD compare
MMP_RS01500 -3.0 -5.4 CBS domain-containing protein compare
MMP_RS08715 -3.0 -2.5 formylmethanofuran dehydrogenase subunit B compare
MMP_RS02355 -2.9 -6.1 30S ribosomal protein S27ae compare
MMP_RS03435 -2.9 -3.5 ketol-acid reductoisomerase compare
MMP_RS03315 -2.8 -2.3 ferrous iron transport protein A compare
MMP_RS06715 -2.8 -17.6 cache domain-containing protein compare
MMP_RS01455 -2.8 -10.2 nickel pincer cofactor biosynthesis protein LarC compare
MMP_RS04605 -2.7 -9.5 cobalt ECF transporter T component CbiQ compare
MMP_RS02010 -2.7 -10.6 PHP domain-containing protein compare
MMP_RS06720 -2.7 -8.5 response regulator transcription factor compare
MMP_RS00695 -2.6 -2.0 biotin--[acetyl-CoA-carboxylase] ligase compare
MMP_RS01700 -2.6 -1.3 dihydroxy-acid dehydratase compare
MMP_RS07185 -2.6 -14.1 pyridoxal phosphate-dependent aminotransferase compare
MMP_RS05875 -2.5 -6.6 hydroxyethylthiazole kinase compare
MMP_RS07730 -2.5 -2.3 pyruvate synthase subunit beta compare
MMP_RS08745 -2.5 -10.0 CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase compare
MMP_RS07735 -2.4 -1.5 2-ketoisovalerate ferredoxin oxidoreductase subunit alpha compare
MMP_RS06375 -2.4 -11.0 ATP-dependent sacrificial sulfur transferase LarE compare
MMP_RS09020 -2.4 -2.6 hypothetical protein compare
MMP_RS06705 -2.4 -10.1 formate/nitrite transporter family protein compare
MMP_RS06975 -2.4 -4.4 sulfide-dependent adenosine diphosphate thiazole synthase compare
MMP_RS06105 -2.4 -8.1 hydrogenase maturation peptidase HycI compare
MMP_RS08720 -2.4 -2.7 4Fe-4S binding protein compare
MMP_RS04215 -2.3 -10.6 nickel pincer cofactor biosynthesis protein LarB compare
MMP_RS07525 -2.3 -10.2 4Fe-4S binding protein compare
MMP_RS00040 -2.3 -5.8 TIGR03576 family pyridoxal phosphate-dependent enzyme compare
MMP_RS07445 -2.3 -7.7 helix-turn-helix domain-containing protein compare
MMP_RS05555 -2.3 -2.2 DUF4040 domain-containing protein compare
MMP_RS02235 -2.3 -11.0 CBS domain-containing protein compare
MMP_RS07365 -2.3 -15.2 2-phosphoglycerate kinase compare
MMP_RS04900 -2.2 -18.5 hypothetical protein compare
MMP_RS04620 -2.2 -10.5 cobalt transporter CbiM compare
MMP_RS00300 -2.2 -1.4 6 7-dimethyl-8-ribityllumazine synthase compare
MMP_RS05930 -2.2 -2.9 3-isopropylmalate dehydratase large subunit compare
MMP_RS06175 -2.1 -9.5 winged helix-turn-helix transcriptional regulator compare
MMP_RS07845 -2.1 -3.1 LL-diaminopimelate aminotransferase compare
MMP_RS01005 -2.1 -1.9 riboflavin synthase compare
MMP_RS04615 -2.1 -4.4 PDGLE domain-containing protein compare
MMP_RS06270 -2.0 -4.9 TIGR00300 family protein compare
MMP_RS00685 -2.0 -5.0 2-phospho-L-lactate guanylyltransferase compare
MMP_RS03035 -2.0 -4.9 4-hydroxy-tetrahydrodipicolinate synthase compare
MMP_RS02195 -1.9 -4.6 tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase compare
MMP_RS07575 -1.9 -4.7 RNA ligase partner protein compare
MMP_RS06400 -1.9 -2.7 4Fe-4S binding protein compare
MMP_RS01985 -1.9 -8.0 F420-dependent methylenetetrahydromethanopterin dehydrogenase compare
MMP_RS00620 -1.9 -10.1 4Fe-4S binding protein compare
MMP_RS04780 -1.8 -3.5 ribonuclease P compare
MMP_RS05425 -1.8 -4.5 monovalent cation/H+ antiporter complex subunit F compare
MMP_RS08820 -1.8 -4.9 hypothetical protein compare
MMP_RS05265 -1.8 -3.5 2-isopropylmalate synthase compare
MMP_RS08330 -1.8 -5.4 NADH-quinone oxidoreductase subunit H compare
MMP_RS06840 -1.8 -1.6 DNA-directed RNA polymerase subunit N compare
MMP_RS03025 -1.7 -5.9 molybdenum cofactor guanylyltransferase compare
MMP_RS01385 -1.7 -0.8 imidazole glycerol phosphate synthase subunit HisH compare
MMP_RS01265 -1.7 -3.0 hypothetical protein compare
MMP_RS04875 -1.6 -5.8 energy-converting hydrogenase B subunit P compare
MMP_RS03600 -1.6 -2.9 triose-phosphate isomerase compare
MMP_RS05765 -1.6 -7.2 M42 family metallopeptidase compare
MMP_RS06285 -1.6 -3.2 precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT compare
MMP_RS01220 -1.6 -7.4 hypothetical protein compare
MMP_RS07630 -1.6 -2.2 ATP-binding cassette domain-containing protein compare
MMP_RS01545 -1.6 -1.7 CBS domain-containing protein compare
MMP_RS08790 -1.6 -2.3 translation initiation factor IF-2 subunit alpha compare
MMP_RS08460 -1.6 -2.7 proteasome-activating nucleotidase compare
MMP_RS05540 -1.6 -3.5 hypothetical protein compare
MMP_RS06340 -1.6 -6.9 phosphoadenosine phosphosulfate reductase family protein compare
MMP_RS06295 -1.5 -6.0 methanogenesis marker 14 protein compare
MMP_RS00115 -1.5 -8.5 radical SAM protein compare
MMP_RS00295 -1.5 -2.6 gamma carbonic anhydrase family protein compare
MMP_RS04890 -1.5 -1.1 adenylyltransferase/cytidyltransferase family protein compare
MMP_RS05060 -1.5 -7.2 AAA family ATPase compare
MMP_RS01795 -1.5 -2.3 methanogenesis marker 6 protein compare
MMP_RS07555 -1.5 -1.2 monovalent cation/H+ antiporter subunit E compare
MMP_RS05095 -1.4 -6.0 CO dehydrogenase/acetyl-CoA synthase complex subunit epsilon compare
MMP_RS01365 -1.4 -2.9 archaeal proteasome endopeptidase complex subunit alpha compare
MMP_RS01610 -1.4 -4.8 hypothetical protein compare
MMP_RS08940 -1.4 -1.5 MetS family NSS transporter small subunit compare
MMP_RS01380 -1.4 -4.6 PHP domain-containing protein compare
MMP_RS06730 -1.4 -2.0 phosphopantothenate/pantothenate synthetase compare
MMP_RS03640 -1.3 -3.3 archaeal proteasome endopeptidase complex subunit beta compare
MMP_RS03485 -1.3 -4.4 TIGR00267 family protein compare
MMP_RS08320 -1.3 -4.9 molybdopterin molybdotransferase MoeA compare
MMP_RS05250 -1.3 -2.5 NFYB/HAP3 family transcription factor subunit compare
MMP_RS01195 -1.3 -1.7 metalloregulator ArsR/SmtB family transcription factor compare
MMP_RS04775 -1.3 -2.8 adenosylhomocysteinase compare
MMP_RS03475 -1.3 -1.0 hypothetical protein compare
MMP_RS04870 -1.3 -5.0 TIGR02253 family HAD-type hydrolase compare
MMP_RS02240 -1.3 -4.6 methanogenesis marker 7 protein compare
MMP_RS00895 -1.3 -2.8 hypothetical protein compare
MMP_RS02885 -1.3 -9.3 molybdopterin biosynthesis protein compare
MMP_RS05090 -1.3 -5.8 CO dehydrogenase/CO-methylating acetyl-CoA synthase complex subunit beta compare
MMP_RS07600 -1.3 -2.4 Ni-sirohydrochlorin a c-diamide synthase compare
MMP_RS05085 -1.3 -6.9 AAA family ATPase compare
MMP_RS07545 -1.3 -1.3 HTH domain-containing protein compare
MMP_RS05080 -1.2 -8.9 acetyl-CoA decarbonylase/synthase complex subunit delta compare
MMP_RS00455 -1.2 -6.3 orotate phosphoribosyltransferase-like protein compare
MMP_RS01085 -1.2 -2.3 hypothetical protein compare
MMP_RS05100 -1.2 -8.9 CO dehydrogenase/acetyl-CoA synthase complex subunit alpha compare
MMP_RS03960 -1.2 -1.5 hypothetical protein compare
MMP_RS05075 -1.2 -8.5 acetyl-CoA decarbonylase/synthase complex subunit gamma compare
MMP_RS06865 -1.2 -1.2 HypC/HybG/HupF family hydrogenase formation chaperone compare
MMP_RS04790 -1.2 -7.1 4-hydroxy-tetrahydrodipicolinate reductase compare
MMP_RS01800 -1.2 -4.7 TIGR00303 family protein compare
MMP_RS01325 -1.2 -1.9 dihydroneopterin aldolase family protein compare
MMP_RS02800 -1.2 -3.5 nucleotidyltransferase domain-containing protein compare
MMP_RS07580 -1.2 -3.8 DUF356 domain-containing protein compare
MMP_RS07860 -1.2 -1.2 hypothetical protein compare
MMP_RS08615 -1.2 -1.2 flagellar protein G compare
MMP_RS05070 -1.1 -6.1 4Fe-4S dicluster domain-containing protein compare
MMP_RS08210 -1.1 -2.1 phosphatidylglycerophosphatase A compare
MMP_RS05055 -1.1 -8.0 DUF166 domain-containing protein compare
MMP_RS03080 -1.1 -2.9 universal stress protein compare
MMP_RS03400 -1.1 -2.2 archease compare
MMP_RS02345 -1.1 -2.5 GTP-dependent dephospho-CoA kinase family protein compare
MMP_RS05245 -1.1 -6.1 archaeosine biosynthesis radical SAM protein RaSEA compare
MMP_RS02340 -1.1 -1.9 DNA-directed RNA polymerase subunit E'' compare
MMP_RS01075 -1.1 -2.1 hypothetical protein compare
MMP_RS04710 -1.1 -1.6 hypothetical protein compare
MMP_RS00130 -1.0 -1.3 nickel-responsive transcriptional regulator NikR compare
MMP_RS06925 -1.0 -3.3 ribonuclease VapC4 compare
MMP_RS04955 -1.0 -3.4 DNA topoisomerase I compare
MMP_RS07535 -1.0 -6.1 4Fe-4S binding protein compare
MMP_RS03445 -1.0 -1.1 methanogenesis marker 17 protein compare
MMP_RS04585 -1.0 -5.6 AIR synthase related protein compare
MMP_RS07005 -1.0 -0.6 4Fe-4S binding protein compare
MMP_RS01445 -1.0 -4.5 hypothetical protein compare
MMP_RS06230 -1.0 -1.8 helix-turn-helix domain-containing protein compare
MMP_RS02280 -1.0 -1.0 DUF211 domain-containing protein compare
MMP_RS00555 -1.0 -3.5 MFS transporter compare
MMP_RS05865 -0.9 -1.7 hypothetical protein compare
MMP_RS05430 -0.9 -5.1 TIGR00288 family NYN domain-containing protein compare
MMP_RS00720 -0.9 -4.5 metal-dependent hydrolase compare
MMP_RS00290 -0.9 -4.5 hypothetical protein compare
MMP_RS04015 -0.9 -2.1 hypothetical protein compare
MMP_RS08300 -0.9 -1.1 metal-sulfur cluster assembly factor compare
MMP_RS09055 -0.9 -1.2 CAP domain-containing protein compare
MMP_RS08435 -0.9 -2.0 Era-like GTP-binding protein compare
MMP_RS06885 -0.9 -1.8 50S ribosome-binding GTPase compare
MMP_RS07200 -0.9 -4.3 [5-(aminomethyl)furan-3-yl]methyl phosphate kinase compare
MMP_RS06625 -0.9 -1.2 DNA primase compare
MMP_RS02900 -0.8 -0.6 imidazoleglycerol-phosphate dehydratase HisB compare
MMP_RS07720 -0.8 -4.8 4Fe-4S binding protein compare
MMP_RS05850 -0.8 -2.5 Ldh family oxidoreductase compare
MMP_RS04125 -0.8 -2.1 TetR/AcrR family transcriptional regulator compare
MMP_RS02165 -0.8 -3.5 tRNA-dihydrouridine synthase compare
MMP_RS00305 -0.8 -1.5 phosphoribosyl-ATP diphosphatase compare
MMP_RS08645 -0.8 -4.0 UPF0179 family protein compare
MMP_RS01745 -0.8 -3.7 AMP phosphorylase compare
MMP_RS03145 -0.8 -3.3 fibrillarin-like rRNA/tRNA 2'-O-methyltransferase compare
MMP_RS02190 -0.8 -2.0 sulfopyruvate decarboxylase subunit alpha compare
MMP_RS08370 -0.8 -0.7 cation:proton antiporter subunit C compare
MMP_RS08350 -0.8 -0.9 hypothetical protein compare
MMP_RS07755 -0.8 -1.1 DUF555 domain-containing protein compare
MMP_RS05910 -0.8 -1.8 cell division ATPase MinD compare
MMP_RS02930 -0.8 -1.8 class I SAM-dependent methyltransferase compare
MMP_RS00110 -0.7 -2.5 hypothetical protein compare
MMP_RS01180 -0.7 -1.0 XTP/dITP diphosphatase compare
MMP_RS01440 -0.7 -2.5 NAAT family transporter compare
MMP_RS08760 -0.7 -1.1 hypothetical protein compare
MMP_RS07625 -0.7 -1.8 cobalt ECF transporter T component CbiQ compare
MMP_RS00515 -0.7 -0.7 DUF655 domain-containing protein compare
MMP_RS00345 -0.7 -3.3 DUF2666 domain-containing protein compare
MMP_RS04035 -0.7 -1.9 hypothetical protein compare
MMP_RS03550 -0.7 -1.7 DUF2124 domain-containing protein compare
MMP_RS06200 -0.7 -4.2 M24 family metallopeptidase compare
MMP_RS02045 -0.7 -1.5 tRNA-Met compare
MMP_RS06930 -0.7 -5.0 MBL fold metallo-hydrolase compare
MMP_RS03305 -0.7 -3.2 winged helix-turn-helix domain-containing protein compare
MMP_RS05815 -0.7 -1.5 NOL1/NOP2/sun family putative RNA methylase compare
MMP_RS07605 -0.7 -2.6 diadenylate cyclase compare
MMP_RS01250 -0.7 -2.5 tRNA (guanine(26)-N(2))-dimethyltransferase compare
MMP_RS01240 -0.7 -0.8 7-cyano-7-deazaguanine synthase QueC compare
MMP_RS05105 -0.7 -4.5 thymidylate synthase compare
MMP_RS07705 -0.7 -3.2 transcriptional regulator compare
MMP_RS06215 -0.7 -2.3 30S ribosomal protein S6e compare
MMP_RS05440 -0.7 -3.2 winged helix-turn-helix transcriptional regulator compare
MMP_RS01575 -0.7 -4.2 aldolase compare
MMP_RS06020 -0.7 -2.1 archaeoflavoprotein AfpA compare
MMP_RS01570 -0.7 -1.2 hypothetical protein compare
MMP_RS04255 -0.6 -3.0 coenzyme F420 hydrogenase subunit beta compare
MMP_RS05845 -0.6 -1.2 tRNA-intron lyase compare
MMP_RS00060 -0.6 -1.3 3-dehydroquinate synthase II compare
MMP_RS08600 -0.6 -1.3 flagellar protein D compare


Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in nutrient t1 experiments

For nutrient t1 L-tyrosine disodium salt across organisms