Experiment set8IT023 for Methanococcus maripaludis S2

Compare to:

Mc formate, casamino free, with 10mM L-Tyrosine

200 most detrimental genes:

  gene name fitness t score description  
MMP_RS03615 +1.7 13.5 4Fe-4S binding protein compare
MMP_RS03620 +1.4 8.9 hypothetical protein compare
MMP_RS01370 +1.2 7.7 acetate--CoA ligase family protein compare
MMP_RS01960 +1.0 1.3 hypothetical protein compare
MMP_RS01540 +0.9 3.8 DUF504 domain-containing protein compare
MMP_RS01775 +0.9 2.5 TIGR00297 family protein compare
MMP_RS03300 +0.9 1.0 TOBE domain-containing protein compare
MMP_RS07390 +0.9 2.8 cell division protein FtsZ compare
MMP_RS04550 +0.9 6.1 S-layer protein compare
MMP_RS07120 +0.8 5.0 coenzyme F420 hydrogenase subunit alpha compare
MMP_RS07820 +0.8 4.5 UPF0104 family protein compare
MMP_RS05355 +0.7 0.9 hypothetical protein compare
MMP_RS06395 +0.7 3.3 ThiF family adenylyltransferase compare
MMP_RS07115 +0.7 4.6 MBL fold metallo-hydrolase compare
MMP_RS08315 +0.7 3.0 S-methyl-5-thioribose-1-phosphate isomerase compare
MMP_RS06570 +0.7 2.1 DUF190 domain-containing protein compare
MMP_RS08265 +0.6 3.5 rubrerythrin compare
MMP_RS01650 +0.6 0.8 sulfurtransferase TusA family protein compare
MMP_RS08705 +0.6 3.9 sulfopyruvate decarboxylase subunit beta compare
MMP_RS07890 +0.6 2.2 OB-fold nucleic acid binding domain-containing protein compare
MMP_RS07125 +0.6 2.6 coenzyme F420-reducing hydrogenase FrhD protein compare
MMP_RS07540 +0.6 2.6 CBS domain-containing protein compare
MMP_RS01895 +0.6 4.6 flippase compare
MMP_RS02780 +0.6 4.1 hypothetical protein compare
MMP_RS01875 +0.6 3.8 N-acetyltransferase compare
MMP_RS01885 +0.6 3.7 Gfo/Idh/MocA family oxidoreductase compare
MMP_RS08155 +0.6 2.9 hypothetical protein compare
MMP_RS07130 +0.6 3.9 coenzyme F420 hydrogenase subunit gamma compare
MMP_RS07695 +0.6 3.7 DUF3236 domain-containing protein compare
MMP_RS05525 +0.6 2.7 calcium/sodium antiporter compare
MMP_RS05640 +0.6 2.8 UTP--glucose-1-phosphate uridylyltransferase GalU compare
MMP_RS08090 +0.5 3.4 hypothetical protein compare
MMP_RS05970 +0.5 2.7 class II SORL domain-containing protein compare
MMP_RS00945 +0.5 1.0 PadR family transcriptional regulator compare
MMP_RS02470 +0.5 0.8 helix-turn-helix transcriptional regulator compare
MMP_RS01525 +0.5 1.4 nucleoside-diphosphate kinase compare
MMP_RS03215 +0.5 3.8 MBL fold metallo-hydrolase compare
MMP_RS04850 +0.5 4.4 UPF0254 family protein compare
MMP_RS01620 +0.5 3.2 hypothetical protein compare
MMP_RS01940 +0.5 1.9 MoxR family ATPase compare
MMP_RS01880 +0.5 3.3 DegT/DnrJ/EryC1/StrS family aminotransferase compare
MMP_RS08500 +0.5 2.2 pyridoxal 5'-phosphate synthase glutaminase subunit PdxT compare
MMP_RS06575 +0.5 1.9 fluoride efflux transporter CrcB compare
MMP_RS06525 +0.5 0.8 YciI family protein compare
MMP_RS01975 +0.5 4.1 hypothetical protein compare
MMP_RS01030 +0.5 1.6 MTAP family purine nucleoside phosphorylase compare
MMP_RS07700 +0.5 3.4 DUF1188 domain-containing protein compare
MMP_RS08440 +0.5 1.6 cell division protein SepF compare
MMP_RS00725 +0.5 2.1 5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdC compare
MMP_RS06900 +0.5 1.4 coenzyme F420-reducing hydrogenase FrhD protein compare
MMP_RS00520 +0.5 0.8 RNA polymerase Rpb4 family protein compare
MMP_RS01910 +0.5 2.9 UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing) compare
MMP_RS00735 +0.5 1.4 5 10-methenyltetrahydromethanopterin hydrogenase compare
MMP_RS07895 +0.5 2.0 cytochrome c compare
MMP_RS04595 +0.4 2.1 hypothetical protein compare
MMP_RS08555 +0.4 2.0 hypothetical protein compare
MMP_RS01685 +0.4 1.5 indolepyruvate oxidoreductase subunit beta compare
MMP_RS03395 +0.4 2.7 hypothetical protein compare
MMP_RS00660 +0.4 2.9 alkaline phosphatase family protein compare
MMP_RS05700 +0.4 2.8 TfuA-related McrA-glycine thioamidation protein compare
MMP_RS06435 +0.4 2.6 CBS domain-containing protein compare
MMP_RS08620 +0.4 2.3 flagellar accessory protein FlaH compare
MMP_RS06545 +0.4 2.2 ferredoxin family protein compare
MMP_RS01805 +0.4 2.1 NUDIX hydrolase compare
MMP_RS06965 +0.4 2.1 TIGR04014 family B12-binding domain/radical SAM domain-containing protein compare
MMP_RS01945 +0.4 2.6 DUF4350 domain-containing protein compare
MMP_RS00100 +0.4 2.9 tRNA pseudouridine(13) synthase TruD compare
MMP_RS01950 +0.4 3.1 hypothetical protein compare
MMP_RS00825 +0.4 2.1 fumarylacetoacetate hydrolase family protein compare
MMP_RS08890 +0.4 3.4 glycosyltransferase family 4 protein compare
MMP_RS08175 +0.4 3.0 7-cyano-7-deazaguanine synthase compare
MMP_RS06535 +0.4 2.1 2-oxoacid:acceptor oxidoreductase family protein compare
MMP_RS03750 +0.4 2.2 ACT domain-containing protein compare
MMP_RS03840 +0.4 1.6 hypothetical protein compare
MMP_RS00185 +0.4 2.9 potassium channel protein compare
MMP_RS02310 +0.4 0.9 RimK-like ATPgrasp N-terminal domain-containing protein compare
MMP_RS02875 +0.4 2.5 chorismate pyruvate-lyase family protein compare
MMP_RS02490 +0.4 1.6 hypothetical protein compare
MMP_RS04720 +0.4 1.1 DedA family protein compare
MMP_RS06745 +0.4 1.6 DUF2119 domain-containing protein compare
MMP_RS07815 +0.4 0.7 DUF2120 domain-containing protein compare
MMP_RS08775 +0.4 1.5 methanogenesis marker 9 domain-containing protein compare
MMP_RS04520 +0.4 1.6 nucleoside deaminase compare
MMP_RS02725 +0.4 1.8 molybdate ABC transporter permease subunit compare
MMP_RS01640 +0.3 2.0 2-oxoacid:acceptor oxidoreductase subunit alpha compare
MMP_RS00630 +0.3 2.0 ECF transporter S component compare
MMP_RS07135 +0.3 2.1 coenzyme F420 hydrogenase subunit beta compare
MMP_RS02740 +0.3 1.2 hypothetical protein compare
MMP_RS06005 +0.3 2.1 heavy-metal-associated domain-containing protein compare
MMP_RS07875 +0.3 1.3 hypothetical protein compare
MMP_RS02815 +0.3 1.3 hypothetical protein compare
MMP_RS00795 +0.3 1.8 formate dehydrogenase H subunit alpha selenocysteine-containing compare
MMP_RS08640 +0.3 2.3 TIM barrel protein compare
MMP_RS06600 +0.3 0.8 class III signal peptide-containing protein compare
MMP_RS06585 +0.3 0.8 DMT family protein compare
MMP_RS01930 +0.3 2.6 hypothetical protein compare
MMP_RS08235 +0.3 1.4 hypothetical protein compare
MMP_RS07095 +0.3 1.3 PspC domain-containing protein compare
MMP_RS01915 +0.3 2.7 DUF354 domain-containing protein compare
MMP_RS00320 +0.3 0.9 class I SAM-dependent methyltransferase compare
MMP_RS06550 +0.3 2.0 AMP-binding protein compare
MMP_RS08605 +0.3 1.5 flagellar protein E compare
MMP_RS00650 +0.3 1.8 ABC transporter ATP-binding protein compare
MMP_RS03420 +0.3 1.1 acetolactate synthase small subunit compare
MMP_RS03245 +0.3 1.4 DNA repair and recombination protein RadB compare
MMP_RS08275 +0.3 1.7 hypothetical protein compare
MMP_RS07590 +0.3 2.3 hypothetical protein compare
MMP_RS00940 +0.3 2.2 daunorubicin resistance protein DrrA family ABC transporter ATP-binding protein compare
MMP_RS09025 +0.3 0.5 hypothetical protein compare
MMP_RS04165 +0.3 1.3 TetR/AcrR family transcriptional regulator compare
MMP_RS03385 +0.3 0.5 cation diffusion facilitator family transporter compare
MMP_RS04145 +0.3 0.7 hypothetical protein compare
MMP_RS06940 +0.3 1.1 polyprenyl diphosphate synthase compare
MMP_RS06765 +0.3 2.0 flap endonuclease-1 compare
MMP_RS05580 +0.3 2.5 glycosyltransferase compare
MMP_RS07100 +0.3 1.7 hypothetical protein compare
MMP_RS00730 +0.3 1.2 5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdB compare
MMP_RS01920 +0.3 2.4 glycosyltransferase family 2 protein compare
MMP_RS03900 +0.3 1.6 minichromosome maintenance protein MCM compare
MMP_RS06530 +0.3 1.3 bifunctional hexulose-6-phosphate synthase/ribonuclease regulator compare
MMP_RS00140 +0.3 1.1 DUF192 domain-containing protein compare
MMP_RS06520 +0.3 1.3 DUF1786 domain-containing protein compare
MMP_RS01980 +0.3 2.2 trimeric intracellular cation channel family protein compare
MMP_RS03350 +0.3 1.3 winged helix-turn-helix domain-containing protein compare
MMP_RS06310 +0.3 1.1 NAD(P)/FAD-dependent oxidoreductase compare
MMP_RS00315 +0.3 1.6 Nif3-like dinuclear metal center hexameric protein compare
MMP_RS05720 +0.3 1.4 signal recognition particle subunit SRP19/SEC65 family protein compare
MMP_RS06905 +0.3 0.6 hypothetical protein compare
MMP_RS01435 +0.3 1.2 DMT family transporter compare
MMP_RS04050 +0.3 1.4 hypothetical protein compare
MMP_RS08405 +0.3 1.7 MFS transporter compare
MMP_RS08470 +0.3 1.7 ATP-binding cassette domain-containing protein compare
MMP_RS02675 +0.3 1.1 hypothetical protein compare
MMP_RS07915 +0.3 1.5 DUF4870 domain-containing protein compare
MMP_RS02910 +0.3 1.6 ABC transporter substrate-binding protein compare
MMP_RS03765 +0.3 1.6 CopG family ribbon-helix-helix protein compare
MMP_RS01935 +0.3 1.7 DUF58 domain-containing protein compare
MMP_RS00635 +0.3 1.1 energy-coupling factor transporter transmembrane protein EcfT compare
MMP_RS02645 +0.3 1.5 ArsR family transcriptional regulator compare
MMP_RS01905 +0.3 2.1 glycosyltransferase compare
MMP_RS03010 +0.3 1.9 cupin domain-containing protein compare
MMP_RS05470 +0.3 1.8 DUF523 and DUF1722 domain-containing protein compare
MMP_RS01460 +0.3 1.0 hypothetical protein compare
MMP_RS05990 +0.3 1.1 DsrE family protein compare
MMP_RS01970 +0.3 2.0 TIGR04279 domain-containing protein compare
MMP_RS03405 +0.3 1.8 RNA 3'-terminal phosphate cyclase compare
MMP_RS03325 +0.2 1.5 hypothetical protein compare
MMP_RS01060 +0.2 1.8 calcium/sodium antiporter compare
MMP_RS08930 +0.2 0.6 hypothetical protein compare
MMP_RS04740 +0.2 1.4 DUF473 domain-containing protein compare
MMP_RS02895 +0.2 1.4 DHH family phosphoesterase compare
MMP_RS05275 +0.2 1.9 AI-2E family transporter compare
MMP_RS06440 +0.2 1.5 CBS domain-containing protein compare
MMP_RS07150 +0.2 1.1 MTH895/ArsE family thioredoxin-like protein compare
MMP_RS02770 +0.2 1.0 hypothetical protein compare
MMP_RS04840 +0.2 1.6 response regulator compare
MMP_RS06555 +0.2 1.0 cupin domain-containing protein compare
MMP_RS00480 +0.2 1.2 hypothetical protein compare
MMP_RS05830 +0.2 0.8 peptidyl-prolyl cis-trans isomerase compare
MMP_RS07330 +0.2 2.1 membrane protein compare
MMP_RS02940 +0.2 1.5 TatD family hydrolase compare
MMP_RS00960 +0.2 1.0 iron export ABC transporter permease subunit FetB compare
MMP_RS05905 +0.2 1.2 undecaprenyl-diphosphate phosphatase compare
MMP_RS04480 +0.2 1.9 lysine 2 3-aminomutase compare
MMP_RS00675 +0.2 0.3 nitroreductase family protein compare
MMP_RS08835 +0.2 1.1 H(2)-dependent methylenetetrahydromethanopterin dehydrogenase-related protein compare
MMP_RS03870 +0.2 1.0 purine NTPase compare
MMP_RS08195 +0.2 1.5 hypothetical protein compare
MMP_RS00085 +0.2 1.5 DNA cytosine methyltransferase compare
MMP_RS03895 +0.2 0.8 hypothetical protein compare
MMP_RS05635 +0.2 1.3 NAD-dependent epimerase/dehydratase family protein compare
MMP_RS00665 +0.2 0.7 hypothetical protein compare
MMP_RS06185 +0.2 1.6 thermonuclease family protein compare
MMP_RS05665 +0.2 1.0 phosphate ABC transporter permease subunit PstC compare
MMP_RS05955 +0.2 0.6 CoB--CoM heterodisulfide reductase subunit C compare
MMP_RS01120 +0.2 1.0 permease compare
MMP_RS05790 +0.2 1.3 HDIG domain-containing protein compare
MMP_RS07805 +0.2 1.0 ABC transporter permease compare
MMP_RS08975 +0.2 1.3 hypothetical protein compare
MMP_RS02970 +0.2 1.2 hypothetical protein compare
MMP_RS06165 +0.2 1.2 ABC transporter permease compare
MMP_RS08310 +0.2 0.6 TMEM165/GDT1 family protein compare
MMP_RS07560 +0.2 1.0 prefoldin subunit alpha compare
MMP_RS05150 +0.2 1.4 hypothetical protein compare
MMP_RS09030 +0.2 0.8 hypothetical protein compare
MMP_RS06895 +0.2 0.4 selenocysteine-specific translation elongation factor compare
MMP_RS09065 +0.2 1.6 hypothetical protein compare
MMP_RS06875 +0.2 1.4 FAD-dependent oxidoreductase compare
MMP_RS01200 +0.2 1.3 hypothetical protein compare
MMP_RS02915 +0.2 1.2 amino acid ABC transporter permease compare
MMP_RS08480 +0.2 1.4 molybdate ABC transporter substrate-binding protein compare
MMP_RS03965 +0.2 0.6 hypothetical protein compare
MMP_RS00955 +0.2 1.4 coenzyme gamma-F420-2:alpha-L-glutamate ligase compare
MMP_RS02810 +0.2 1.1 hypothetical protein compare
MMP_RS04970 +0.2 1.6 F420-dependent thioredoxin reductase compare
MMP_RS05980 +0.2 1.2 ferritin compare
MMP_RS06610 +0.2 0.7 DUF2334 domain-containing protein compare
MMP_RS04475 +0.2 1.1 nitrogen fixation compare
MMP_RS09050 +0.2 0.9 CAP domain-containing protein compare
MMP_RS01065 +0.2 1.5 alpha/beta hydrolase compare


Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in nutrient t1 experiments

For nutrient t1 L-tyrosine disodium salt across organisms