Experiment set8IT022 for Pseudomonas fluorescens FW300-N2E2

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Uridine nitrogen source

200 most important genes:

  gene name fitness t score description  
Pf6N2E2_3630 -6.4 -4.4 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_4597 -6.4 -6.2 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_3783 -6.3 -4.3 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
Pf6N2E2_64 -6.1 -4.2 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) compare
Pf6N2E2_77 -5.9 -4.1 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) compare
Pf6N2E2_4825 -5.8 -6.9 Anthranilate phosphoribosyltransferase (EC 2.4.2.18) compare
Pf6N2E2_5006 -5.7 -6.8 Muramoyltetrapeptide carboxypeptidase (EC 3.4.17.13) compare
Pf6N2E2_3253 -5.6 -5.5 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
Pf6N2E2_3782 -5.6 -3.9 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) compare
Pf6N2E2_2258 -5.6 -9.3 Transaldolase (EC 2.2.1.2) compare
Pf6N2E2_4596 -5.5 -9.3 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_5175 -5.5 -12.2 Acetolactate synthase large subunit (EC 2.2.1.6) compare
Pf6N2E2_5177 -5.4 -12.0 Ketol-acid reductoisomerase (EC 1.1.1.86) compare
Pf6N2E2_4826 -5.4 -8.9 Indole-3-glycerol phosphate synthase (EC 4.1.1.48) compare
Pf6N2E2_71 -5.3 -7.3 Phosphoribosylanthranilate isomerase (EC 5.3.1.24) compare
Pf6N2E2_3751 -5.3 -14.5 Glutamate synthase [NADPH] small chain (EC 1.4.1.13) compare
Pf6N2E2_3842 -5.2 -6.1 Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) compare
Pf6N2E2_4047 -5.1 -6.0 Tryptophan synthase alpha chain (EC 4.2.1.20) compare
Pf6N2E2_2588 -5.1 -4.9 Anti-sigma F factor antagonist (spoIIAA-2); Anti-sigma B factor antagonist RsbV compare
Pf6N2E2_3248 -5.0 -6.3 Probable transmembrane protein compare
Pf6N2E2_5176 -5.0 -9.6 Acetolactate synthase small subunit (EC 2.2.1.6) compare
Pf6N2E2_3826 -5.0 -5.9 Nitrogen regulation protein NR(I) compare
Pf6N2E2_5150 -5.0 -5.9 Glucose-6-phosphate isomerase (EC 5.3.1.9) compare
Pf6N2E2_3752 -4.9 -22.9 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) compare
Pf6N2E2_1186 -4.9 -6.7 Permease of the drug/metabolite transporter (DMT) superfamily compare
Pf6N2E2_500 -4.9 -4.7 Beta-ureidopropionase (EC 3.5.1.6) compare
Pf6N2E2_4564 -4.8 -10.7 Dihydroxy-acid dehydratase (EC 4.2.1.9) compare
Pf6N2E2_5014 -4.7 -1.9 Apolipoprotein N-acyltransferase (EC 2.3.1.-) / Copper homeostasis protein CutE compare
Pf6N2E2_3825 -4.7 -6.4 Nitrogen regulation protein NtrB (EC 2.7.13.3) compare
Pf6N2E2_2885 -4.6 -4.5 Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) compare
Pf6N2E2_3839 -4.6 -5.4 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
Pf6N2E2_4372 -4.5 -4.3 FIG00460773: hypothetical protein compare
Pf6N2E2_496 -4.4 -12.5 Dihydropyrimidine dehydrogenase (NADP(+)) (EC 1.3.1.2) (from data) conserved
Pf6N2E2_3610 -4.2 -4.6 ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) compare
Pf6N2E2_3841 -4.1 -6.3 Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) compare
Pf6N2E2_66 -4.1 -9.3 3-isopropylmalate dehydrogenase (EC 1.1.1.85) compare
Pf6N2E2_3941 -4.1 -3.9 Adenosine (5')-pentaphospho-(5'')-adenosine pyrophosphohydrolase (EC 3.6.1.-) compare
Pf6N2E2_497 -4.0 -7.0 Pyridine nucleotide-disulphide oxidoreductase associated with reductive pyrimidine catabolism conserved
Pf6N2E2_3252 -3.9 -8.7 Histidinol dehydrogenase (EC 1.1.1.23) compare
Pf6N2E2_5156 -3.9 -2.7 Two-component sensor CbrB: intrcellular carbon:nitrogen balance compare
Pf6N2E2_4353 -3.9 -4.8 Hydrogen peroxide-inducible genes activator compare
Pf6N2E2_1187 -3.8 -9.1 Probable nikkomycin biosynthesis protein, carboxylase compare
Pf6N2E2_3072 -3.7 -13.6 [Protein-PII] uridylyltransferase (EC 2.7.7.59) compare
Pf6N2E2_4048 -3.6 -6.4 Tryptophan synthase beta chain (EC 4.2.1.20) compare
Pf6N2E2_4638 -3.6 -3.5 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) compare
Pf6N2E2_2117 -3.4 -16.7 1,4-alpha-glucan (glycogen) branching enzyme, GH-13-type (EC 2.4.1.18) compare
Pf6N2E2_3940 -3.4 -10.6 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_2073 -3.4 -9.8 Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2) compare
Pf6N2E2_499 -3.3 -6.4 Possible pyrimidine permease in reductive pathway conserved
Pf6N2E2_2074 -3.2 -1.8 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) compare
Pf6N2E2_5160 -3.2 -2.2 C4-type zinc finger protein, DksA/TraR family compare
Pf6N2E2_3463 -3.2 -12.8 Omega-amino acid--pyruvate aminotransferase (EC 2.6.1.18) conserved
Pf6N2E2_3932 -3.2 -3.9 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) compare
Pf6N2E2_5242 -3.1 -2.1 Malate:quinone oxidoreductase (EC 1.1.5.4) compare
Pf6N2E2_4279 -3.1 -12.6 Pyruvate carboxyl transferase subunit B (EC 6.4.1.1) compare
Pf6N2E2_3460 -3.1 -2.1 Exodeoxyribonuclease V beta chain (EC 3.1.11.5) compare
Pf6N2E2_3554 -3.0 -8.4 GCN5-related N-acetyltransferase compare
Pf6N2E2_498 -3.0 -6.1 Dihydropyrimidinase (EC 3.5.2.2) (from data) conserved
Pf6N2E2_4278 -3.0 -11.2 Pyruvate carboxyl transferase subunit A (EC 6.4.1.1) compare
Pf6N2E2_3942 -2.8 -9.9 FIG001592: Phosphocarrier protein kinase/phosphorylase, nitrogen regulation associated compare
Pf6N2E2_658 -2.8 -9.4 sensor histidine kinase compare
Pf6N2E2_3074 -2.8 -2.3 FIG00960973: hypothetical protein compare
Pf6N2E2_63 -2.7 -4.6 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) compare
Pf6N2E2_3170 -2.7 -6.5 2-isopropylmalate synthase (EC 2.3.3.13) compare
Pf6N2E2_1189 -2.7 -8.0 Thioredoxin reductase (EC 1.8.1.9) compare
Pf6N2E2_2218 -2.7 -5.9 ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92) compare
Pf6N2E2_4391 -2.6 -5.7 D-amino acid dehydrogenase small subunit (EC 1.4.99.1) compare
Pf6N2E2_4743 -2.6 -1.5 hypothetical protein compare
Pf6N2E2_3464 -2.6 -10.1 LysR family transcriptional regulator PA0133 conserved
Pf6N2E2_5679 -2.5 -4.8 hypothetical protein compare
Pf6N2E2_3251 -2.5 -9.4 histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) compare
Pf6N2E2_5261 -2.4 -1.7 FIG00956983: hypothetical protein compare
Pf6N2E2_4277 -2.4 -8.5 LysR family transcriptional regulator PA5437 compare
Pf6N2E2_1056 -2.3 -1.2 Quinone oxidoreductase (EC 1.6.5.5) compare
Pf6N2E2_4071 -2.3 -5.1 Phosphate transport system regulatory protein PhoU compare
Pf6N2E2_4759 -2.3 -13.7 Biotin synthase (EC 2.8.1.6) compare
Pf6N2E2_3938 -2.3 -12.2 Threonine dehydratase biosynthetic (EC 4.3.1.19) compare
Pf6N2E2_5579 -2.3 -5.4 Ornithine carbamoyltransferase (EC 2.1.3.3) compare
Pf6N2E2_1188 -2.1 -4.8 Alpha-ketoglutarate-dependent taurine dioxygenase (EC 1.14.11.17) compare
Pf6N2E2_4009 -2.1 -9.3 GGDEF domain protein compare
Pf6N2E2_5494 -2.0 -5.6 Pyruvate kinase (EC 2.7.1.40) compare
Pf6N2E2_1190 -2.0 -5.3 Glutamine-dependent 2-keto-4-methylthiobutyrate transaminase compare
Pf6N2E2_3349 -2.0 -3.0 Polyribonucleotide nucleotidyltransferase (EC 2.7.7.8) compare
Pf6N2E2_2514 -1.9 -5.9 regulator of length of O-antigen component of lipopolysaccharide chains compare
Pf6N2E2_3060 -1.9 -3.6 Outer membrane protein H precursor compare
Pf6N2E2_3984 -1.9 -8.3 T1SS associated transglutaminase-like cysteine proteinase LapP compare
Pf6N2E2_4153 -1.8 -2.1 Sensory box histidine kinase compare
Pf6N2E2_1116 -1.8 -1.7 Inosine-5'-monophosphate dehydrogenase (EC 1.1.1.205) compare
Pf6N2E2_2277 -1.8 -3.5 NADPH-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.13) compare
Pf6N2E2_1656 -1.7 -3.8 hypothetical protein compare
Pf6N2E2_4987 -1.7 -1.6 MaoC-like domain protein compare
Pf6N2E2_5666 -1.7 -7.9 Arginine N-succinyltransferase, alpha subunit (EC 2.3.1.109) compare
Pf6N2E2_3677 -1.7 -9.5 Sensory box/GGDEF family protein compare
Pf6N2E2_3257 -1.6 -3.8 Uncharacterized ABC transporter, auxiliary component YrbC compare
Pf6N2E2_4416 -1.6 -2.4 Tyrosine recombinase XerC compare
Pf6N2E2_3908 -1.6 -5.9 Glutamate--cysteine ligase (EC 6.3.2.2) compare
Pf6N2E2_4417 -1.6 -3.0 Protein of unknown function DUF484 compare
Pf6N2E2_3607 -1.6 -6.2 3'-to-5' exoribonuclease RNase R compare
Pf6N2E2_2510 -1.6 -4.2 Lipid carrier : UDP-N-acetylgalactosaminyltransferase (EC 2.4.1.-) / Alpha-1,3-N-acetylgalactosamine transferase PglA (EC 2.4.1.-); Putative glycosyltransferase compare
Pf6N2E2_5178 -1.5 -2.5 CDP-diacylglycerol--serine O-phosphatidyltransferase (EC 2.7.8.8) compare
Pf6N2E2_3258 -1.5 -4.9 Uncharacterized ABC transporter, periplasmic component YrbD compare
Pf6N2E2_2375 -1.5 -2.1 Response regulator NasT compare
Pf6N2E2_2465 -1.5 -6.0 Cys regulon transcriptional activator CysB compare
Pf6N2E2_3835 -1.5 -3.0 Carboxyl-terminal protease (EC 3.4.21.102) compare
Pf6N2E2_3206 -1.5 -1.7 hypothetical protein compare
Pf6N2E2_3271 -1.4 -2.4 Phosphocarrier protein, nitrogen regulation associated compare
Pf6N2E2_3807 -1.4 -4.7 Histidine utilization repressor compare
Pf6N2E2_5258 -1.4 -6.9 Sulfate adenylyltransferase subunit 1 (EC 2.7.7.4) / Adenylylsulfate kinase (EC 2.7.1.25) compare
Pf6N2E2_5425 -1.4 -1.6 hypothetical protein compare
Pf6N2E2_4276 -1.3 -4.8 Phosphogluconate repressor HexR, RpiR family compare
Pf6N2E2_2219 -1.3 -2.3 Cell division trigger factor (EC 5.2.1.8) compare
Pf6N2E2_2225 -1.3 -1.9 FIG00953489: hypothetical protein compare
Pf6N2E2_3834 -1.3 -5.6 Lipoprotein NlpD compare
Pf6N2E2_2899 -1.3 -3.9 NAD-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12) compare
Pf6N2E2_4612 -1.3 -3.8 Glutathione synthetase (EC 6.3.2.3) compare
Pf6N2E2_3885 -1.3 -2.0 3'(2'),5'-bisphosphate nucleotidase (EC 3.1.3.7) compare
Pf6N2E2_89 -1.3 -2.1 hypothetical protein compare
Pf6N2E2_2706 -1.2 -2.0 Allophanate hydrolase 2 subunit 2 (EC 3.5.1.54) compare
Pf6N2E2_3260 -1.2 -3.3 Uncharacterized ABC transporter, ATP-binding protein YrbF compare
Pf6N2E2_1577 -1.2 -3.0 Glucose 1-dehydrogenase (EC 1.1.1.47) compare
Pf6N2E2_698 -1.2 -1.8 Heme d1 biosynthesis protein NirH compare
Pf6N2E2_2864 -1.2 -2.2 Gluconokinase (EC 2.7.1.12) compare
Pf6N2E2_2480 -1.2 -1.6 FIG00957636: hypothetical protein compare
Pf6N2E2_5527 -1.2 -1.8 Cold shock protein CspC compare
Pf6N2E2_302 -1.2 -3.3 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) compare
Pf6N2E2_2574 -1.2 -1.5 Flagellar synthesis regulator FleN compare
Pf6N2E2_4579 -1.2 -1.7 Ribosomal RNA small subunit methyltransferase D (EC 2.1.1.-) compare
Pf6N2E2_3240 -1.2 -1.6 Methylated-DNA--protein-cysteine methyltransferase (EC 2.1.1.63) compare
Pf6N2E2_50 -1.2 -5.2 Biosynthetic Aromatic amino acid aminotransferase alpha (EC 2.6.1.57) @ Aromatic-amino-acid aminotransferase (EC 2.6.1.57) compare
Pf6N2E2_3869 -1.2 -6.5 Branched-chain amino acid transport protein AzlC compare
Pf6N2E2_818 -1.2 -4.5 Chemotaxis regulator - transmits chemoreceptor signals to flagelllar motor components CheY compare
Pf6N2E2_4369 -1.1 -1.8 Exodeoxyribonuclease III (EC 3.1.11.2) compare
Pf6N2E2_1191 -1.1 -4.8 Thiaminase II (EC 3.5.99.2) compare
Pf6N2E2_737 -1.1 -1.7 Ribonucleotide reductase of class III (anaerobic), activating protein (EC 1.97.1.4) compare
Pf6N2E2_2852 -1.1 -6.8 GGDEF domain/EAL domain protein compare
Pf6N2E2_4611 -1.1 -3.1 Ferric siderophore transport system, periplasmic binding protein TonB compare
Pf6N2E2_831 -1.1 -1.9 Ketoacyl reductase hetN (EC 1.3.1.-) compare
Pf6N2E2_2513 -1.1 -3.1 UDP-glucose dehydrogenase (EC 1.1.1.22) compare
Pf6N2E2_5705 -1.1 -1.3 Sensor protein PhoQ (EC 2.7.13.3) compare
Pf6N2E2_2124 -1.1 -1.8 Mg(2+) transport ATPase protein C compare
Pf6N2E2_420 -1.1 -1.3 Chemotaxis regulator - transmits chemoreceptor signals to flagelllar motor components CheY compare
Pf6N2E2_5316 -1.1 -1.3 Periplasmic thiol:disulfide oxidoreductase DsbB, required for DsbA reoxidation compare
Pf6N2E2_724 -1.1 -1.3 Nitric oxide -responding transcriptional regulator Dnr (Crp/Fnr family) compare
Pf6N2E2_5676 -1.1 -2.5 Aspartokinase (EC 2.7.2.4) compare
Pf6N2E2_5257 -1.1 -5.4 Sulfate adenylyltransferase subunit 2 (EC 2.7.7.4) compare
Pf6N2E2_2186 -1.1 -4.2 Isovaleryl-CoA dehydrogenase (EC 1.3.8.4) compare
Pf6N2E2_4464 -1.1 -2.1 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases / CDP-6-deoxy-delta-3,4-glucoseen reductase-like compare
Pf6N2E2_4454 -1.0 -3.9 Exopolyphosphatase (EC 3.6.1.11) compare
Pf6N2E2_2503 -1.0 -1.7 Glycosyl transferase, group 1 family protein compare
Pf6N2E2_1705 -1.0 -1.4 Branched-chain amino acid transport ATP-binding protein LivG (TC 3.A.1.4.1) compare
Pf6N2E2_5027 -1.0 -6.3 AMP nucleosidase (EC 3.2.2.4) compare
Pf6N2E2_1691 -1.0 -1.7 hypothetical protein compare
Pf6N2E2_2509 -1.0 -1.3 UDP-glucose 4-epimerase (EC 5.1.3.2) compare
Pf6N2E2_3849 -1.0 -1.6 FIG00954739: hypothetical protein compare
Pf6N2E2_2261 -1.0 -4.8 VacJ-like lipoprotein precursor compare
Pf6N2E2_1317 -1.0 -3.5 P-hydroxyphenylacetate hydroxylase C2:oxygenase component compare
Pf6N2E2_1281 -1.0 -2.4 ATPase involved in DNA repair compare
Pf6N2E2_2549 -1.0 -1.0 hypothetical protein compare
Pf6N2E2_613 -1.0 -1.3 lipoprotein, putative compare
Pf6N2E2_4661 -0.9 -2.6 KluA regulatory protein compare
Pf6N2E2_5944 -0.9 -3.1 Ribosomal large subunit pseudouridine synthase C (EC 4.2.1.70) compare
Pf6N2E2_1136 -0.9 -2.1 Transcriptional regulator, TetR family compare
Pf6N2E2_1966 -0.9 -1.7 SAM-dependent methyltransferases compare
Pf6N2E2_2472 -0.9 -2.3 hypothetical protein compare
Pf6N2E2_4077 -0.9 -1.6 cytosolic long-chain acyl-CoA thioester hydrolase family protein compare
Pf6N2E2_5728 -0.9 -2.5 Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) compare
Pf6N2E2_3505 -0.9 -0.9 Translation initiation factor SUI1-related protein compare
Pf6N2E2_902 -0.9 -1.6 hypothetical protein compare
Pf6N2E2_2927 -0.9 -3.0 Putative signal peptide protein compare
Pf6N2E2_4658 -0.9 -3.2 FIG00955006: hypothetical protein compare
Pf6N2E2_3027 -0.9 -1.0 Baseplate assembly protein V compare
Pf6N2E2_4818 -0.9 -3.2 Spermidine Putrescine ABC transporter permease component potC (TC_3.A.1.11.1) compare
Pf6N2E2_3786 -0.9 -2.1 Twin-arginine translocation protein TatC compare
Pf6N2E2_2217 -0.9 -3.1 ATP-dependent Clp protease ATP-binding subunit ClpX compare
Pf6N2E2_2253 -0.9 -1.5 hypothetical protein compare
Pf6N2E2_4412 -0.9 -4.9 Ammonium transporter compare
Pf6N2E2_2897 -0.9 -4.8 Glucokinase (EC 2.7.1.2) compare
Pf6N2E2_2274 -0.9 -3.4 Soluble pyridine nucleotide transhydrogenase (EC 1.6.1.1) compare
Pf6N2E2_5510 -0.9 -2.7 FIG00955324: hypothetical protein compare
Pf6N2E2_4352 -0.9 -1.5 ATP-dependent DNA helicase RecG (EC 3.6.1.-) compare
Pf6N2E2_2753 -0.9 -1.3 HtrA protease/chaperone protein compare
Pf6N2E2_1932 -0.9 -3.5 Transcriptional regulator, IclR family compare
Pf6N2E2_4764 -0.9 -3.5 Dethiobiotin synthetase (EC 6.3.3.3) compare
Pf6N2E2_3255 -0.9 -1.6 YrbA protein compare
Pf6N2E2_477 -0.9 -2.6 Branched-chain amino acid aminotransferase (EC 2.6.1.42) compare
Pf6N2E2_2473 -0.9 -1.0 Major outer membrane lipoprotein I compare
Pf6N2E2_4453 -0.9 -6.6 Polyphosphate kinase (EC 2.7.4.1) compare
Pf6N2E2_3847 -0.9 -2.2 FIG001341: Probable Fe(2+)-trafficking protein YggX compare
Pf6N2E2_1718 -0.9 -2.5 Anthranilate synthase, amidotransferase component (EC 4.1.3.27) compare
Pf6N2E2_3351 -0.9 -2.5 tRNA pseudouridine synthase B (EC 4.2.1.70) compare
Pf6N2E2_4928 -0.8 -1.6 Permeases of the major facilitator superfamily compare
Pf6N2E2_3204 -0.8 -1.8 Rho-specific inhibitor of transcription termination (YaeO) compare
Pf6N2E2_919 -0.8 -1.2 FIG00954373: hypothetical protein compare
Pf6N2E2_1279 -0.8 -2.4 Putative PpiC-type peptidyl-prolyl cis-trans isomerase precursor associated with VreARI signaling system compare
Pf6N2E2_1037 -0.8 -1.8 hypothetical protein compare
Pf6N2E2_3300 -0.8 -2.1 Predicted D-glucarate or D-galactorate regulator, GntR family compare
Pf6N2E2_1169 -0.8 -2.0 TnpR protein compare
Pf6N2E2_292 -0.8 -4.2 ATP-dependent Clp protease ATP-binding subunit ClpA compare
Pf6N2E2_5219 -0.8 -4.4 FIG140336: TPR domain protein compare
Pf6N2E2_2292 -0.8 -1.7 Universal stress protein family COG0589 compare


Specific Phenotypes

For 8 genes in this experiment

For nitrogen source Uridine in Pseudomonas fluorescens FW300-N2E2

For nitrogen source Uridine across organisms