Experiment set8IT020 for Methanococcus maripaludis S2

Compare to:

Mc formate, casamino free, with 10mM L-Methionine

200 most detrimental genes:

  gene name fitness t score description  
MMP_RS01370 +2.4 12.5 acetate--CoA ligase family protein compare
MMP_RS06395 +1.8 6.3 ThiF family adenylyltransferase compare
MMP_RS07125 +1.6 4.5 coenzyme F420-reducing hydrogenase FrhD protein compare
MMP_RS07695 +1.5 8.3 DUF3236 domain-containing protein compare
MMP_RS03300 +1.5 1.3 TOBE domain-containing protein compare
MMP_RS05355 +1.5 1.4 hypothetical protein compare
MMP_RS07700 +1.4 8.0 DUF1188 domain-containing protein compare
MMP_RS07115 +1.3 5.7 MBL fold metallo-hydrolase compare
MMP_RS00725 +1.3 3.9 5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdC compare
MMP_RS04850 +1.3 10.3 UPF0254 family protein compare
MMP_RS03340 +1.3 1.2 ABC transporter ATP-binding protein compare
MMP_RS08310 +1.2 2.6 TMEM165/GDT1 family protein compare
MMP_RS00735 +1.2 3.4 5 10-methenyltetrahydromethanopterin hydrogenase compare
MMP_RS06525 +1.1 1.5 YciI family protein compare
MMP_RS08500 +1.1 5.2 pyridoxal 5'-phosphate synthase glutaminase subunit PdxT compare
MMP_RS03215 +1.1 6.3 MBL fold metallo-hydrolase compare
MMP_RS00730 +1.1 3.3 5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdB compare
MMP_RS05535 +1.0 2.9 hypothetical protein compare
MMP_RS07915 +1.0 2.4 DUF4870 domain-containing protein compare
MMP_RS02675 +0.9 2.0 hypothetical protein compare
MMP_RS07120 +0.9 4.8 coenzyme F420 hydrogenase subunit alpha compare
MMP_RS00310 +0.9 6.4 CBS domain-containing protein compare
MMP_RS06575 +0.9 2.6 fluoride efflux transporter CrcB compare
MMP_RS00315 +0.9 5.7 Nif3-like dinuclear metal center hexameric protein compare
MMP_RS02230 +0.9 5.8 sodium-dependent transporter compare
MMP_RS07875 +0.9 3.7 hypothetical protein compare
MMP_RS02790 +0.9 1.2 class III signal peptide-containing protein compare
MMP_RS07820 +0.9 2.6 UPF0104 family protein compare
MMP_RS07130 +0.9 4.4 coenzyme F420 hydrogenase subunit gamma compare
MMP_RS07560 +0.8 4.3 prefoldin subunit alpha compare
MMP_RS00185 +0.8 5.9 potassium channel protein compare
MMP_RS05975 +0.8 1.2 hypothetical protein compare
MMP_RS08155 +0.8 3.6 hypothetical protein compare
MMP_RS08280 +0.8 1.9 proteasome assembly chaperone family protein compare
MMP_RS08555 +0.8 2.4 hypothetical protein compare
MMP_RS06570 +0.8 3.8 DUF190 domain-containing protein compare
MMP_RS05675 +0.8 1.4 phosphate ABC transporter ATP-binding protein PstB compare
MMP_RS01775 +0.8 1.5 TIGR00297 family protein compare
MMP_RS02475 +0.7 2.1 hypothetical protein compare
MMP_RS06610 +0.7 2.2 DUF2334 domain-containing protein compare
MMP_RS06765 +0.7 3.9 flap endonuclease-1 compare
MMP_RS06590 +0.7 1.8 GNAT family N-acetyltransferase compare
MMP_RS01940 +0.7 2.1 MoxR family ATPase compare
MMP_RS07850 +0.7 1.6 prephenate dehydratase compare
MMP_RS00430 +0.7 1.4 hypothetical protein compare
MMP_RS06745 +0.7 2.6 DUF2119 domain-containing protein compare
MMP_RS08620 +0.6 2.8 flagellar accessory protein FlaH compare
MMP_RS02295 +0.6 3.3 TatD family hydrolase compare
MMP_RS01965 +0.6 2.3 DUF1616 domain-containing protein compare
MMP_RS07135 +0.6 3.3 coenzyme F420 hydrogenase subunit beta compare
MMP_RS06905 +0.6 1.7 hypothetical protein compare
MMP_RS08670 +0.6 2.6 metallophosphoesterase compare
MMP_RS08415 +0.6 1.6 radical SAM protein compare
MMP_RS08455 +0.6 2.1 multiprotein bridging factor aMBF1 compare
MMP_RS00660 +0.6 3.1 alkaline phosphatase family protein compare
MMP_RS02390 +0.6 2.2 NifB/NifX family molybdenum-iron cluster-binding protein compare
MMP_RS07885 +0.6 1.0 tripartite tricarboxylate transporter permease compare
MMP_RS00155 +0.5 2.1 heavy metal-binding domain-containing protein compare
MMP_RS05525 +0.5 2.6 calcium/sodium antiporter compare
MMP_RS00665 +0.5 2.5 hypothetical protein compare
MMP_RS05470 +0.5 3.1 DUF523 and DUF1722 domain-containing protein compare
MMP_RS03890 +0.5 2.7 DUF2540 domain-containing protein compare
MMP_RS05830 +0.5 1.9 peptidyl-prolyl cis-trans isomerase compare
MMP_RS08265 +0.5 2.1 rubrerythrin compare
MMP_RS02895 +0.5 2.0 DHH family phosphoesterase compare
MMP_RS07895 +0.5 1.7 cytochrome c compare
MMP_RS03910 +0.5 1.0 hypothetical protein compare
MMP_RS00140 +0.5 1.9 DUF192 domain-containing protein compare
MMP_RS06320 +0.5 2.0 hypothetical protein compare
MMP_RS02490 +0.5 0.9 hypothetical protein compare
MMP_RS08390 +0.5 1.5 DUF5400 domain-containing protein compare
MMP_RS01865 +0.5 0.8 GPR1/FUN34/YaaH family transporter compare
MMP_RS05695 +0.5 1.4 phospholipase D-like domain-containing protein compare
MMP_RS01895 +0.5 3.3 flippase compare
MMP_RS06065 +0.4 3.3 iron ABC transporter substrate-binding protein compare
MMP_RS00960 +0.4 2.0 iron export ABC transporter permease subunit FetB compare
MMP_RS07860 +0.4 0.5 hypothetical protein compare
MMP_RS01095 +0.4 1.5 iron ABC transporter permease compare
MMP_RS08090 +0.4 2.0 hypothetical protein compare
MMP_RS01460 +0.4 1.3 hypothetical protein compare
MMP_RS08930 +0.4 0.8 hypothetical protein compare
MMP_RS08260 +0.4 2.5 DUF99 family protein compare
MMP_RS08175 +0.4 2.2 7-cyano-7-deazaguanine synthase compare
MMP_RS06075 +0.4 1.6 class I SAM-dependent methyltransferase compare
MMP_RS00565 +0.4 2.0 CBS domain-containing protein compare
MMP_RS02815 +0.4 1.2 hypothetical protein compare
MMP_RS03150 +0.4 2.8 phosphoglycerate mutase compare
MMP_RS06335 +0.4 1.9 HAD family hydrolase compare
MMP_RS00125 +0.4 0.6 DUF2798 domain-containing protein compare
MMP_RS06325 +0.4 0.6 hypothetical protein compare
MMP_RS00520 +0.4 0.4 RNA polymerase Rpb4 family protein compare
MMP_RS00380 +0.4 1.8 P-II family nitrogen regulator compare
MMP_RS02290 +0.4 1.7 MBL fold metallo-hydrolase compare
MMP_RS08475 +0.4 1.7 ABC transporter permease compare
MMP_RS06250 +0.4 1.4 hypothetical protein compare
MMP_RS09065 +0.4 2.6 hypothetical protein compare
MMP_RS08160 +0.4 1.9 EamA family transporter compare
MMP_RS06560 +0.4 2.3 hypothetical protein compare
MMP_RS08945 +0.4 2.3 hypothetical protein compare
MMP_RS06600 +0.4 0.5 class III signal peptide-containing protein compare
MMP_RS07880 +0.4 1.5 AAA family ATPase compare
MMP_RS06965 +0.4 0.9 TIGR04014 family B12-binding domain/radical SAM domain-containing protein compare
MMP_RS03110 +0.4 1.4 glycosyltransferase family 2 protein compare
MMP_RS05820 +0.4 1.7 RNA-binding transcriptional accessory protein compare
MMP_RS01540 +0.4 1.1 DUF504 domain-containing protein compare
MMP_RS04720 +0.4 0.8 DedA family protein compare
MMP_RS06770 +0.4 1.5 DHH family phosphoesterase compare
MMP_RS04315 +0.4 2.2 corrinoid protein compare
MMP_RS00675 +0.4 0.4 nitroreductase family protein compare
MMP_RS07855 +0.4 1.5 class I SAM-dependent methyltransferase compare
MMP_RS01525 +0.4 0.7 nucleoside-diphosphate kinase compare
MMP_RS00980 +0.4 2.0 hypothetical protein compare
MMP_RS06290 +0.4 1.5 DNA repair and recombination protein RadA compare
MMP_RS06015 +0.4 1.2 flavodoxin family protein compare
MMP_RS00650 +0.4 2.0 ABC transporter ATP-binding protein compare
MMP_RS06490 +0.4 1.9 hypothetical protein compare
MMP_RS02130 +0.4 1.1 zinc metalloprotease HtpX compare
MMP_RS08700 +0.4 1.7 hypothetical protein compare
MMP_RS04275 +0.4 1.7 hydrogenase iron-sulfur subunit compare
MMP_RS03465 +0.3 0.5 adenine phosphoribosyltransferase compare
MMP_RS07970 +0.3 1.1 hypothetical protein compare
MMP_RS08275 +0.3 1.6 hypothetical protein compare
MMP_RS08480 +0.3 2.3 molybdate ABC transporter substrate-binding protein compare
MMP_RS08980 +0.3 1.2 hypothetical protein compare
MMP_RS00800 +0.3 2.1 Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain compare
MMP_RS08235 +0.3 1.9 hypothetical protein compare
MMP_RS01080 +0.3 1.0 DUF2202 domain-containing protein compare
MMP_RS02580 +0.3 1.3 cupin domain-containing protein compare
MMP_RS03245 +0.3 1.0 DNA repair and recombination protein RadB compare
MMP_RS05490 +0.3 1.0 IMPACT family protein compare
MMP_RS00740 +0.3 0.9 cyclase family protein compare
MMP_RS07085 +0.3 1.7 ribonuclease HII compare
MMP_RS01930 +0.3 2.3 hypothetical protein compare
MMP_RS08835 +0.3 1.7 H(2)-dependent methylenetetrahydromethanopterin dehydrogenase-related protein compare
MMP_RS02605 +0.3 0.4 MotA/TolQ/ExbB proton channel family protein compare
MMP_RS05825 +0.3 1.1 peptidyl-prolyl cis-trans isomerase compare
MMP_RS07150 +0.3 1.2 MTH895/ArsE family thioredoxin-like protein compare
MMP_RS03115 +0.3 2.3 hypothetical protein compare
MMP_RS05600 +0.3 2.6 AglZ/HisF2 family acetamidino modification protein compare
MMP_RS00135 +0.3 1.2 DUF2121 domain-containing protein compare
MMP_RS07985 +0.3 2.0 nitroreductase family protein compare
MMP_RS06520 +0.3 1.3 DUF1786 domain-containing protein compare
MMP_RS07815 +0.3 0.4 DUF2120 domain-containing protein compare
MMP_RS03520 +0.3 0.8 YwbE family protein compare
MMP_RS06500 +0.3 1.6 ATP-binding protein compare
MMP_RS08430 +0.3 1.4 HAD family hydrolase compare
MMP_RS07145 +0.3 1.6 AmmeMemoRadiSam system protein B compare
MMP_RS01485 +0.3 1.6 right-handed parallel beta-helix repeat-containing protein compare
MMP_RS07805 +0.3 1.1 ABC transporter permease compare
MMP_RS02310 +0.3 0.5 RimK-like ATPgrasp N-terminal domain-containing protein compare
MMP_RS02045 +0.3 0.6 tRNA-Met compare
MMP_RS00280 +0.3 1.9 DUF2118 domain-containing protein compare
MMP_RS05970 +0.3 1.3 class II SORL domain-containing protein compare
MMP_RS08205 +0.3 1.5 stage II sporulation protein M compare
MMP_RS07155 +0.3 1.8 MFS transporter compare
MMP_RS08285 +0.3 1.3 serine/threonine protein kinase compare
MMP_RS03535 +0.3 0.8 helix-turn-helix transcriptional regulator compare
MMP_RS02395 +0.3 1.2 hypothetical protein compare
MMP_RS04945 +0.3 0.8 hypothetical protein compare
MMP_RS08325 +0.3 2.2 hypothetical protein compare
MMP_RS07770 +0.3 0.9 alanine racemase compare
MMP_RS06480 +0.3 1.3 ABC transporter substrate-binding protein compare
MMP_RS00640 +0.3 1.3 ABC transporter substrate-binding protein compare
MMP_RS01875 +0.3 1.7 N-acetyltransferase compare
MMP_RS06655 +0.3 1.7 glycoside hydrolase family 15 protein compare
MMP_RS05895 +0.3 1.8 metallophosphoesterase compare
MMP_RS07840 +0.3 0.5 ribonuclease III compare
MMP_RS03100 +0.3 0.6 hypothetical protein compare
MMP_RS05665 +0.3 1.3 phosphate ABC transporter permease subunit PstC compare
MMP_RS05790 +0.3 1.4 HDIG domain-containing protein compare
MMP_RS00085 +0.3 1.6 DNA cytosine methyltransferase compare
MMP_RS08890 +0.3 2.2 glycosyltransferase family 4 protein compare
MMP_RS00195 +0.3 2.4 DUF4013 domain-containing protein compare
MMP_RS01100 +0.3 0.4 ABC transporter ATP-binding protein compare
MMP_RS07590 +0.3 1.8 hypothetical protein compare
MMP_RS01860 +0.3 1.1 hypothetical protein compare
MMP_RS07725 +0.3 1.1 4Fe-4S dicluster domain-containing protein compare
MMP_RS07910 +0.3 1.4 NAD(P)H-hydrate dehydratase compare
MMP_RS06280 +0.3 1.3 alpha-glucan family phosphorylase compare
MMP_RS03010 +0.3 1.9 cupin domain-containing protein compare
MMP_RS08630 +0.3 1.3 archaellar assembly protein FlaJ compare
MMP_RS03080 +0.3 0.4 universal stress protein compare
MMP_RS02775 +0.3 1.8 hypothetical protein compare
MMP_RS08685 +0.3 1.8 hypothetical protein compare
MMP_RS01055 +0.3 0.8 hypothetical protein compare
MMP_RS00795 +0.3 1.5 formate dehydrogenase H subunit alpha selenocysteine-containing compare
MMP_RS08490 +0.3 1.9 hypothetical protein compare
MMP_RS04050 +0.3 0.8 hypothetical protein compare
MMP_RS08665 +0.3 1.9 hypothetical protein compare
MMP_RS00625 +0.3 1.7 hypothetical protein compare
MMP_RS03785 +0.3 0.9 cupin domain-containing protein compare
MMP_RS05900 +0.3 1.4 tetratricopeptide repeat protein compare
MMP_RS08380 +0.3 1.3 phosphatase PAP2 family protein compare
MMP_RS00545 +0.3 0.7 XRE family transcriptional regulator compare
MMP_RS08640 +0.3 1.5 TIM barrel protein compare
MMP_RS01640 +0.3 1.3 2-oxoacid:acceptor oxidoreductase subunit alpha compare
MMP_RS05945 +0.3 1.1 CBS domain-containing protein compare
MMP_RS01430 +0.3 0.8 mechanosensitive ion channel family protein compare
MMP_RS05835 +0.3 0.2 secondary thiamine-phosphate synthase enzyme YjbQ compare
MMP_RS02410 +0.3 0.7 ABC transporter substrate-binding protein compare


Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in nutrient t1 experiments

For nutrient t1 L-Methionine across organisms