Experiment set8IT019 for Methanococcus maripaludis S2

Compare to:

Mc formate, casamino free, with 10mM L-Methionine

200 most important genes:

  gene name fitness t score description  
MMP_RS07345 -5.4 -9.0 glycine synthesis protein GlyXL (from data) compare
MMP_RS08165 -4.8 -3.3 phosphoglycerate dehydrogenase compare
MMP_RS06355 -4.7 -3.2 molybdenum cofactor biosynthesis protein MoaE compare
MMP_RS02195 -4.6 -5.3 tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase compare
MMP_RS05500 -4.3 -10.6 2-isopropylmalate synthase compare
MMP_RS02010 -4.1 -13.5 PHP domain-containing protein compare
MMP_RS01175 -4.1 -5.1 triphosphoribosyl-dephospho-CoA synthase compare
MMP_RS05550 -4.1 -0.6 cation:proton antiporter compare
MMP_RS06680 -4.1 -18.3 Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain compare
MMP_RS03015 -4.0 -10.1 GTP 3' 8-cyclase MoaA compare
MMP_RS03315 -4.0 -1.5 ferrous iron transport protein A compare
MMP_RS06715 -3.9 -20.8 cache domain-containing protein compare
MMP_RS05515 -3.9 -7.2 cyclic pyranopterin monophosphate synthase MoaC compare
MMP_RS05265 -3.8 -2.6 2-isopropylmalate synthase compare
MMP_RS06685 -3.8 -17.6 formate dehydrogenase H subunit alpha selenocysteine-containing compare
MMP_RS06350 -3.8 -5.2 HesA/MoeB/ThiF family protein compare
MMP_RS01500 -3.8 -2.8 CBS domain-containing protein compare
MMP_RS03435 -3.8 -2.3 ketol-acid reductoisomerase compare
MMP_RS09020 -3.7 -1.9 hypothetical protein compare
MMP_RS03450 -3.7 -2.9 glycine synthesis protein GlyXS (from data) compare
MMP_RS06720 -3.7 -8.8 response regulator transcription factor compare
MMP_RS03640 -3.7 -4.7 archaeal proteasome endopeptidase complex subunit beta compare
MMP_RS07635 -3.6 -10.1 MogA/MoaB family molybdenum cofactor biosynthesis protein compare
MMP_RS07185 -3.6 -14.4 pyridoxal phosphate-dependent aminotransferase compare
MMP_RS01455 -3.6 -10.3 nickel pincer cofactor biosynthesis protein LarC compare
MMP_RS06700 -3.6 -18.2 hypothetical protein compare
MMP_RS08790 -3.5 -2.8 translation initiation factor IF-2 subunit alpha compare
MMP_RS03035 -3.5 -4.5 4-hydroxy-tetrahydrodipicolinate synthase compare
MMP_RS02355 -3.5 -3.8 30S ribosomal protein S27ae compare
MMP_RS04870 -3.5 -6.9 TIGR02253 family HAD-type hydrolase compare
MMP_RS06705 -3.5 -9.2 formate/nitrite transporter family protein compare
MMP_RS07845 -3.4 -2.3 LL-diaminopimelate aminotransferase compare
MMP_RS06175 -3.4 -10.3 winged helix-turn-helix transcriptional regulator compare
MMP_RS00295 -3.4 -2.6 gamma carbonic anhydrase family protein compare
MMP_RS04215 -3.4 -12.4 nickel pincer cofactor biosynthesis protein LarB compare
MMP_RS05555 -3.4 -1.5 DUF4040 domain-containing protein compare
MMP_RS07630 -3.4 -1.7 ATP-binding cassette domain-containing protein compare
MMP_RS02800 -3.4 -5.3 nucleotidyltransferase domain-containing protein compare
MMP_RS06345 -3.4 -9.7 formate dehydrogenase accessory sulfurtransferase FdhD compare
MMP_RS06105 -3.3 -12.0 hydrogenase maturation peptidase HycI compare
MMP_RS08745 -3.3 -9.3 CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase compare
MMP_RS07730 -3.3 -2.1 pyruvate synthase subunit beta compare
MMP_RS04790 -3.2 -15.6 4-hydroxy-tetrahydrodipicolinate reductase compare
MMP_RS07365 -3.2 -12.5 2-phosphoglycerate kinase compare
MMP_RS06375 -3.2 -7.0 ATP-dependent sacrificial sulfur transferase LarE compare
MMP_RS00695 -3.2 -1.4 biotin--[acetyl-CoA-carboxylase] ligase compare
MMP_RS04620 -3.2 -15.8 cobalt transporter CbiM compare
MMP_RS01830 -3.2 -2.1 tRNA-Val compare
MMP_RS08820 -3.1 -7.1 hypothetical protein compare
MMP_RS00040 -3.1 -5.5 TIGR03576 family pyridoxal phosphate-dependent enzyme compare
MMP_RS04615 -3.1 -4.2 PDGLE domain-containing protein compare
MMP_RS04585 -3.1 -11.7 AIR synthase related protein compare
MMP_RS00300 -3.1 -0.9 6 7-dimethyl-8-ribityllumazine synthase compare
MMP_RS06840 -3.1 -1.2 DNA-directed RNA polymerase subunit N compare
MMP_RS02340 -3.0 -2.4 DNA-directed RNA polymerase subunit E'' compare
MMP_RS07735 -3.0 -0.9 2-ketoisovalerate ferredoxin oxidoreductase subunit alpha compare
MMP_RS08460 -2.9 -3.4 proteasome-activating nucleotidase compare
MMP_RS06885 -2.9 -3.2 50S ribosome-binding GTPase compare
MMP_RS06270 -2.9 -6.1 TIGR00300 family protein compare
MMP_RS06630 -2.9 -1.1 UPF0058 family protein compare
MMP_RS01755 -2.9 -1.7 DUF2097 domain-containing protein compare
MMP_RS05875 -2.8 -3.6 hydroxyethylthiazole kinase compare
MMP_RS04900 -2.8 -18.1 hypothetical protein compare
MMP_RS07445 -2.8 -7.1 helix-turn-helix domain-containing protein compare
MMP_RS03305 -2.8 -8.7 winged helix-turn-helix domain-containing protein compare
MMP_RS06925 -2.8 -3.2 ribonuclease VapC4 compare
MMP_RS04605 -2.8 -4.8 cobalt ECF transporter T component CbiQ compare
MMP_RS00115 -2.8 -13.8 radical SAM protein compare
MMP_RS07545 -2.8 -1.5 HTH domain-containing protein compare
MMP_RS03600 -2.8 -2.3 triose-phosphate isomerase compare
MMP_RS07525 -2.7 -9.6 4Fe-4S binding protein compare
MMP_RS03025 -2.7 -6.9 molybdenum cofactor guanylyltransferase compare
MMP_RS04875 -2.7 -4.8 energy-converting hydrogenase B subunit P compare
MMP_RS04780 -2.7 -4.2 ribonuclease P compare
MMP_RS05425 -2.7 -5.0 monovalent cation/H+ antiporter complex subunit F compare
MMP_RS04890 -2.6 -0.8 adenylyltransferase/cytidyltransferase family protein compare
MMP_RS01005 -2.6 -1.7 riboflavin synthase compare
MMP_RS00110 -2.6 -3.9 hypothetical protein compare
MMP_RS05085 -2.6 -12.0 AAA family ATPase compare
MMP_RS09055 -2.6 -1.3 CAP domain-containing protein compare
MMP_RS05070 -2.6 -7.5 4Fe-4S dicluster domain-containing protein compare
MMP_RS02280 -2.6 -1.1 DUF211 domain-containing protein compare
MMP_RS01020 -2.5 -1.3 3 4-dihydroxy-2-butanone-4-phosphate synthase compare
MMP_RS01220 -2.5 -8.0 hypothetical protein compare
MMP_RS05095 -2.5 -7.9 CO dehydrogenase/acetyl-CoA synthase complex subunit epsilon compare
MMP_RS01985 -2.5 -7.4 F420-dependent methylenetetrahydromethanopterin dehydrogenase compare
MMP_RS06730 -2.5 -2.3 phosphopantothenate/pantothenate synthetase compare
MMP_RS05850 -2.5 -4.4 Ldh family oxidoreductase compare
MMP_RS01225 -2.5 -5.9 DUF5379 domain-containing protein compare
MMP_RS05100 -2.4 -16.2 CO dehydrogenase/acetyl-CoA synthase complex subunit alpha compare
MMP_RS02885 -2.4 -15.1 molybdopterin biosynthesis protein compare
MMP_RS05505 -2.4 -12.6 class IV adenylate cyclase compare
MMP_RS05060 -2.4 -10.9 AAA family ATPase compare
MMP_RS05080 -2.4 -13.2 acetyl-CoA decarbonylase/synthase complex subunit delta compare
MMP_RS08320 -2.4 -6.2 molybdopterin molybdotransferase MoeA compare
MMP_RS05925 -2.3 -3.1 small nuclear ribonucleoprotein compare
MMP_RS05075 -2.3 -16.0 acetyl-CoA decarbonylase/synthase complex subunit gamma compare
MMP_RS08330 -2.3 -6.9 NADH-quinone oxidoreductase subunit H compare
MMP_RS08300 -2.3 -1.4 metal-sulfur cluster assembly factor compare
MMP_RS06625 -2.3 -2.1 DNA primase compare
MMP_RS00290 -2.2 -7.8 hypothetical protein compare
MMP_RS07960 -2.2 -8.1 sugar phosphate isomerase/epimerase compare
MMP_RS05090 -2.2 -8.3 CO dehydrogenase/CO-methylating acetyl-CoA synthase complex subunit beta compare
MMP_RS08240 -2.2 -5.6 methanogenesis marker 16 metalloprotein compare
MMP_RS01380 -2.2 -4.9 PHP domain-containing protein compare
MMP_RS05765 -2.2 -4.8 M42 family metallopeptidase compare
MMP_RS05055 -2.2 -12.3 DUF166 domain-containing protein compare
MMP_RS02345 -2.2 -3.9 GTP-dependent dephospho-CoA kinase family protein compare
MMP_RS03960 -2.2 -1.3 hypothetical protein compare
MMP_RS08715 -2.2 -2.1 formylmethanofuran dehydrogenase subunit B compare
MMP_RS02235 -2.1 -7.7 CBS domain-containing protein compare
MMP_RS06400 -2.1 -1.7 4Fe-4S binding protein compare
MMP_RS08940 -2.1 -1.2 MetS family NSS transporter small subunit compare
MMP_RS01195 -2.1 -1.5 metalloregulator ArsR/SmtB family transcription factor compare
MMP_RS07580 -2.1 -3.2 DUF356 domain-containing protein compare
MMP_RS03400 -2.1 -2.5 archease compare
MMP_RS08435 -2.1 -2.8 Era-like GTP-binding protein compare
MMP_RS01610 -2.1 -3.4 hypothetical protein compare
MMP_RS05540 -2.0 -2.9 hypothetical protein compare
MMP_RS00305 -2.0 -1.9 phosphoribosyl-ATP diphosphatase compare
MMP_RS05930 -2.0 -2.2 3-isopropylmalate dehydratase large subunit compare
MMP_RS01545 -2.0 -1.3 CBS domain-containing protein compare
MMP_RS04775 -2.0 -2.7 adenosylhomocysteinase compare
MMP_RS05250 -2.0 -2.1 NFYB/HAP3 family transcription factor subunit compare
MMP_RS08840 -2.0 -11.0 class I SAM-dependent methyltransferase compare
MMP_RS07575 -2.0 -3.9 RNA ligase partner protein compare
MMP_RS00050 -2.0 -8.7 AarF/UbiB family protein compare
MMP_RS03485 -2.0 -5.2 TIGR00267 family protein compare
MMP_RS05065 -2.0 -4.6 CooT family nickel-binding protein compare
MMP_RS07645 -1.9 -5.4 aldehyde dehydrogenase family protein compare
MMP_RS01250 -1.9 -3.5 tRNA (guanine(26)-N(2))-dimethyltransferase compare
MMP_RS05280 -1.9 -7.1 COG1361 S-layer family protein compare
MMP_RS05430 -1.9 -6.9 TIGR00288 family NYN domain-containing protein compare
MMP_RS07955 -1.9 -5.7 FumA C-terminus/TtdB family hydratase beta subunit compare
MMP_RS08645 -1.9 -6.1 UPF0179 family protein compare
MMP_RS07555 -1.9 -0.8 monovalent cation/H+ antiporter subunit E compare
MMP_RS00130 -1.9 -1.3 nickel-responsive transcriptional regulator NikR compare
MMP_RS03140 -1.9 -8.6 hypothetical protein compare
MMP_RS03145 -1.9 -5.8 fibrillarin-like rRNA/tRNA 2'-O-methyltransferase compare
MMP_RS04500 -1.9 -10.6 adenosylmethionine--8-amino-7-oxononanoate transaminase compare
MMP_RS02190 -1.8 -2.2 sulfopyruvate decarboxylase subunit alpha compare
MMP_RS03475 -1.8 -0.8 hypothetical protein compare
MMP_RS01440 -1.8 -4.0 NAAT family transporter compare
MMP_RS07685 -1.8 -4.8 TIGR01212 family radical SAM protein compare
MMP_RS00320 -1.8 -1.9 class I SAM-dependent methyltransferase compare
MMP_RS03440 -1.8 -1.3 MoaD/ThiS family protein compare
MMP_RS05920 -1.8 -0.6 50S ribosomal protein L37e compare
MMP_RS01840 -1.8 -5.7 TIGR00289 family protein compare
MMP_RS02170 -1.8 -4.1 CBS domain-containing protein compare
MMP_RS05815 -1.8 -2.6 NOL1/NOP2/sun family putative RNA methylase compare
MMP_RS05285 -1.8 -5.8 MMPL family transporter compare
MMP_RS07600 -1.8 -2.8 Ni-sirohydrochlorin a c-diamide synthase compare
MMP_RS07720 -1.8 -9.4 4Fe-4S binding protein compare
MMP_RS06295 -1.8 -5.0 methanogenesis marker 14 protein compare
MMP_RS01445 -1.8 -6.7 hypothetical protein compare
MMP_RS01725 -1.8 -2.6 class I SAM-dependent methyltransferase family protein compare
MMP_RS07385 -1.8 -2.8 protein translocase SEC61 complex subunit gamma compare
MMP_RS00750 -1.7 -2.7 fumarate hydratase compare
MMP_RS06475 -1.7 -4.5 FAD-dependent oxidoreductase compare
MMP_RS07195 -1.7 -7.0 M20 family metallo-hydrolase compare
MMP_RS00620 -1.7 -5.8 4Fe-4S binding protein compare
MMP_RS08725 -1.7 -1.9 Ni/Fe hydrogenase subunit alpha compare
MMP_RS08100 -1.7 -6.1 8-amino-7-oxononanoate synthase compare
MMP_RS00515 -1.7 -1.0 DUF655 domain-containing protein compare
MMP_RS07380 -1.7 -1.8 transcription elongation factor Spt5 compare
MMP_RS03095 -1.7 -4.9 diphthine synthase compare
MMP_RS06370 -1.7 -4.9 biotin synthase BioB compare
MMP_RS01365 -1.7 -1.9 archaeal proteasome endopeptidase complex subunit alpha compare
MMP_RS04710 -1.7 -1.7 hypothetical protein compare
MMP_RS02240 -1.7 -3.1 methanogenesis marker 7 protein compare
MMP_RS07535 -1.6 -5.9 4Fe-4S binding protein compare
MMP_RS00685 -1.6 -3.6 2-phospho-L-lactate guanylyltransferase compare
MMP_RS05845 -1.6 -2.1 tRNA-intron lyase compare
MMP_RS08105 -1.6 -6.2 6-carboxyhexanoate--CoA ligase compare
MMP_RS00985 -1.6 -5.1 CDC48 family AAA ATPase compare
MMP_RS08590 -1.6 -4.9 flagellin compare
MMP_RS02875 -1.6 -6.8 chorismate pyruvate-lyase family protein compare
MMP_RS06285 -1.6 -1.9 precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT compare
MMP_RS06895 -1.6 -1.2 selenocysteine-specific translation elongation factor compare
MMP_RS08605 -1.5 -4.7 flagellar protein E compare
MMP_RS00555 -1.5 -4.6 MFS transporter compare
MMP_RS03205 -1.5 -1.2 peptidyl-tRNA hydrolase Pth2 compare
MMP_RS08095 -1.5 -5.2 dethiobiotin synthase compare
MMP_RS01795 -1.5 -1.6 methanogenesis marker 6 protein compare
MMP_RS04685 -1.5 -2.3 DUF126 domain-containing protein compare
MMP_RS02900 -1.5 -0.6 imidazoleglycerol-phosphate dehydratase HisB compare
MMP_RS07005 -1.5 -0.5 4Fe-4S binding protein compare
MMP_RS00895 -1.5 -3.3 hypothetical protein compare
MMP_RS01085 -1.5 -1.7 hypothetical protein compare
MMP_RS01800 -1.4 -2.5 TIGR00303 family protein compare
MMP_RS00810 -1.4 -5.3 topoisomerase DNA-binding C4 zinc finger domain-containing protein compare
MMP_RS05345 -1.4 -5.6 hypothetical protein compare
MMP_RS08210 -1.4 -1.4 phosphatidylglycerophosphatase A compare
MMP_RS06865 -1.4 -1.5 HypC/HybG/HupF family hydrogenase formation chaperone compare
MMP_RS08785 -1.4 -0.9 RNA-protein complex protein Nop10 compare
MMP_RS01140 -1.4 -2.7 molybdate ABC transporter permease subunit compare
MMP_RS08690 -1.4 -4.4 RNA-guided pseudouridylation complex pseudouridine synthase subunit Cbf5 compare
MMP_RS08635 -1.4 -1.5 UbiA family prenyltransferase compare
MMP_RS01330 -1.4 -8.5 DHH family phosphoesterase compare
MMP_RS06215 -1.4 -1.8 30S ribosomal protein S6e compare


Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in nutrient t1 experiments

For nutrient t1 L-Methionine across organisms