Experiment set8IT019 for Klebsiella michiganensis M5al

Compare to:

Mix of RCH2_defined_noCarbon and Fungal_growth_media_mCAFEs_v1_noCarbon; D-Glucose at 55.5 mM

200 most important genes:

  gene name fitness t score description  
BWI76_RS20355 -9.5 -6.5 colicin V production protein compare
BWI76_RS00850 -9.4 -9.2 acetylglutamate kinase compare
BWI76_RS00805 -9.4 -6.5 5,10-methylenetetrahydrofolate reductase compare
BWI76_RS04250 -9.3 -6.4 homoserine kinase compare
BWI76_RS20350 -9.0 -8.8 amidophosphoribosyltransferase compare
BWI76_RS00990 -8.9 -6.2 ketol-acid reductoisomerase compare
BWI76_RS18940 -8.4 -5.8 imidazole glycerol phosphate synthase subunit HisH compare
BWI76_RS04465 -8.0 -5.5 carbamoyl-phosphate synthase small subunit compare
BWI76_RS18920 -7.9 -5.5 ATP phosphoribosyltransferase compare
BWI76_RS21265 -7.9 -14.2 phosphoribosylformylglycinamidine synthase compare
BWI76_RS01615 -7.9 -7.7 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase compare
BWI76_RS07070 -7.8 -5.4 5-(carboxyamino)imidazole ribonucleotide mutase compare
BWI76_RS21475 -7.7 -7.8 bifunctional chorismate mutase/prephenate dehydrogenase compare
BWI76_RS00980 -7.7 -10.5 PLP-dependent threonine dehydratase compare
BWI76_RS05835 -7.6 -5.3 gamma-glutamyl-phosphate reductase compare
BWI76_RS02995 -7.6 -9.1 aspartate carbamoyltransferase compare
BWI76_RS00785 -7.6 -5.2 cystathionine gamma-synthase compare
BWI76_RS04470 -7.5 -8.9 carbamoyl phosphate synthase large subunit compare
BWI76_RS18955 -7.5 -6.8 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase compare
BWI76_RS00985 -7.4 -7.3 transcriptional regulator IlvY compare
BWI76_RS04670 -7.4 -10.2 3-isopropylmalate dehydratase large subunit compare
BWI76_RS08385 -7.3 -4.2 citrate (Si)-synthase compare
BWI76_RS20895 -7.2 -7.0 phosphoribosylaminoimidazolesuccinocarboxamide synthase compare
BWI76_RS11860 -7.2 -9.4 anthranilate synthase component I compare
BWI76_RS27385 -7.0 -6.8 orotate phosphoribosyltransferase compare
BWI76_RS23360 -7.0 -4.8 diaminopimelate decarboxylase compare
BWI76_RS11855 -7.0 -7.4 bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase compare
BWI76_RS18935 -7.0 -7.0 bifunctional imidazole glycerol-phosphate dehydratase/histidinol phosphatase compare
BWI76_RS04685 -6.9 -11.6 putative leucine operon leader peptide compare
BWI76_RS04255 -6.9 -10.0 threonine synthase compare
BWI76_RS09645 -6.9 -2.8 thioredoxin-disulfide reductase compare
BWI76_RS05015 -6.8 -4.7 transcriptional regulator compare
BWI76_RS23365 -6.8 -5.2 LysR family transcriptional regulator compare
BWI76_RS04245 -6.8 -14.9 bifunctional aspartate kinase/homoserine dehydrogenase I compare
BWI76_RS01655 -6.7 -9.6 homoserine O-succinyltransferase compare
BWI76_RS04665 -6.7 -22.2 3-isopropylmalate dehydratase small subunit compare
BWI76_RS24285 -6.7 -6.8 cystathionine beta-lyase compare
BWI76_RS18925 -6.6 -7.8 histidinol dehydrogenase compare
BWI76_RS04680 -6.5 -15.7 2-isopropylmalate synthase compare
BWI76_RS07065 -6.5 -7.5 5-(carboxyamino)imidazole ribonucleotide synthase compare
BWI76_RS04160 -6.4 -6.9 phosphoserine phosphatase compare
BWI76_RS23220 -6.4 -9.1 amino-acid N-acetyltransferase compare
BWI76_RS00845 -6.4 -8.7 N-acetyl-gamma-glutamyl-phosphate reductase compare
BWI76_RS26085 -6.4 -4.4 3-dehydroquinate synthase compare
BWI76_RS20965 -6.4 -4.8 phosphoribosylformylglycinamidine cyclo-ligase compare
BWI76_RS05840 -6.3 -7.6 glutamate 5-kinase compare
BWI76_RS09910 -6.3 -18.8 dihydroorotate dehydrogenase (quinone) compare
BWI76_RS11850 -6.3 -10.6 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase compare
BWI76_RS11965 -6.3 -4.2 orotidine-5'-phosphate decarboxylase compare
BWI76_RS27390 -6.3 -5.8 ribonuclease PH compare
BWI76_RS18950 -6.2 -5.0 imidazole glycerol phosphate synthase cyclase subunit compare
BWI76_RS04645 -6.1 -5.9 3-dehydroquinase compare
BWI76_RS18930 -6.0 -5.7 histidinol-phosphate transaminase compare
BWI76_RS17975 -6.0 -5.8 tail-specific protease compare
BWI76_RS04510 -5.9 -4.0 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) compare
BWI76_RS09755 -5.9 -6.1 phosphoserine transaminase compare
BWI76_RS00835 -5.7 -14.3 phosphoenolpyruvate carboxylase compare
BWI76_RS11840 -5.6 -4.8 tryptophan synthase subunit alpha compare
BWI76_RS00855 -5.6 -10.1 argininosuccinate lyase compare
BWI76_RS11845 -5.6 -2.2 tryptophan synthase subunit beta compare
BWI76_RS00975 -5.6 -8.0 dihydroxy-acid dehydratase compare
BWI76_RS04675 -5.6 -7.3 3-isopropylmalate dehydrogenase compare
BWI76_RS01200 -5.4 -3.7 diaminopimelate epimerase compare
BWI76_RS13920 -5.4 -7.7 magnesium-translocating P-type ATPase compare
BWI76_RS01610 -5.3 -4.5 phosphoribosylamine--glycine ligase compare
BWI76_RS03010 -5.3 -6.2 ornithine carbamoyltransferase compare
BWI76_RS17980 -5.3 -5.7 RNA chaperone ProQ compare
BWI76_RS21465 -5.2 -5.2 bifunctional chorismate mutase/prephenate dehydratase compare
BWI76_RS22765 -5.2 -10.4 sulfite reductase subunit alpha compare
BWI76_RS22755 -5.2 -9.8 phosphoadenosine phosphosulfate reductase compare
BWI76_RS04240 -5.1 -2.2 thr operon leader peptide compare
BWI76_RS10990 -5.1 -5.5 dihydroorotase compare
BWI76_RS23920 -5.0 -6.9 D-3-phosphoglycerate dehydrogenase compare
BWI76_RS17720 -4.7 -1.9 muramoyltetrapeptide carboxypeptidase compare
BWI76_RS26940 -4.6 -8.4 transcriptional regulator compare
BWI76_RS15115 -4.6 -5.5 MFS transporter compare
BWI76_RS02735 -4.6 -4.5 3'(2'),5'-bisphosphate nucleotidase CysQ compare
BWI76_RS00400 -4.5 -3.1 glutamine synthetase compare
BWI76_RS25115 -4.5 -5.3 argininosuccinate synthase compare
BWI76_RS22690 -4.5 -4.4 adenylyl-sulfate kinase compare
BWI76_RS27305 -4.4 -10.3 glycosyl transferase compare
BWI76_RS00960 -4.4 -5.9 acetolactate synthase 2 catalytic subunit compare
BWI76_RS25320 -4.4 -8.6 glutamate synthase compare
BWI76_RS09760 -4.3 -2.9 3-phosphoshikimate 1-carboxyvinyltransferase compare
BWI76_RS26000 -4.3 -8.1 aspartate aminotransferase family protein compare
BWI76_RS23240 -4.3 -2.9 exonuclease V subunit gamma compare
BWI76_RS20435 -4.2 -2.4 chorismate synthase compare
BWI76_RS25645 -4.2 -6.6 shikimate dehydrogenase compare
BWI76_RS22760 -4.2 -9.7 sulfite reductase subunit beta compare
BWI76_RS00180 -4.2 -2.3 F0F1 ATP synthase subunit epsilon compare
BWI76_RS26570 -3.9 -4.9 anion permease compare
BWI76_RS21370 -3.8 -3.7 ATP-dependent RNA helicase SrmB compare
BWI76_RS01210 -3.7 -2.7 tyrosine recombinase XerC compare
BWI76_RS09660 -3.6 -2.5 DNA translocase FtsK compare
BWI76_RS26455 -3.5 -4.6 4-amino-4-deoxy-L-arabinose-phospho-UDP flippase compare
BWI76_RS15225 -3.3 -2.7 DeoR family transcriptional regulator compare
BWI76_RS26460 -3.2 -5.7 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE compare
BWI76_RS08580 -3.2 -7.1 quinolinate synthetase compare
BWI76_RS01800 -3.2 -6.7 glucose-6-phosphate isomerase compare
BWI76_RS05200 -3.2 -2.9 bifunctional uridylyltransferase/uridylyl-removing protein compare
BWI76_RS04100 -3.2 -6.6 peptide chain release factor 3 compare
BWI76_RS20640 -3.1 -7.8 cysteine synthase A compare
BWI76_RS23230 -3.1 -3.0 exodeoxyribonuclease V subunit beta compare
BWI76_RS25065 -3.1 -4.5 polyribonucleotide nucleotidyltransferase compare
BWI76_RS01535 -3.1 -9.3 thiazole synthase compare
BWI76_RS01550 -3.0 -7.3 thiamine phosphate synthase compare
BWI76_RS01540 -3.0 -3.2 thiamine biosynthesis protein ThiS compare
BWI76_RS06395 -3.0 -6.0 tRNA 4-thiouridine(8) synthase ThiI compare
BWI76_RS25315 -2.9 -9.6 glutamate synthase large subunit compare
BWI76_RS23480 -2.9 -13.0 EAL domain-containing protein compare
BWI76_RS02580 -2.8 -2.0 23S rRNA (guanosine(2251)-2'-O)-methyltransferase compare
BWI76_RS20650 -2.8 -3.3 phosphoenolpyruvate--protein phosphotransferase compare
BWI76_RS05450 -2.8 -2.0 ribonuclease HI compare
BWI76_RS01275 -2.7 -7.7 LysR family transcriptional regulator compare
BWI76_RS26055 -2.7 -8.7 siroheme synthase compare
BWI76_RS25335 -2.6 -4.3 stringent starvation protein A compare
BWI76_RS00965 -2.6 -1.8 acetolactate synthase 2 small subunit compare
BWI76_RS06525 -2.6 -5.9 ATP-dependent Clp protease proteolytic subunit compare
BWI76_RS01555 -2.5 -7.7 phosphomethylpyrimidine synthase ThiC conserved
BWI76_RS09655 -2.5 -5.2 leucine-responsive regulatory protein compare
BWI76_RS27430 -2.5 -1.9 (p)ppGpp synthetase compare
BWI76_RS23265 -2.4 -4.9 hypothetical protein compare
BWI76_RS01530 -2.3 -4.0 2-iminoacetate synthase ThiH compare
BWI76_RS02530 -2.3 -2.7 tRNA dimethylallyltransferase compare
BWI76_RS20440 -2.2 -1.2 50S ribosomal protein L3 N(5)-glutamine methyltransferase compare
BWI76_RS15850 -2.2 -1.6 DUF1317 domain-containing protein compare
BWI76_RS06535 -2.1 -4.0 endopeptidase La compare
BWI76_RS04845 -2.1 -7.0 nicotinate-nucleotide pyrophosphorylase compare
BWI76_RS24850 -2.1 -6.9 DeoR family transcriptional regulator compare
BWI76_RS20995 -2.1 -5.3 RNA degradosome polyphosphate kinase compare
BWI76_RS00345 -2.1 -3.0 protein disulfide oxidoreductase DsbA compare
BWI76_RS19380 -2.0 -2.6 hydroxyethylthiazole kinase compare
BWI76_RS04705 -2.0 -5.0 DNA-binding transcriptional regulator FruR compare
BWI76_RS06530 -2.0 -5.4 ATP-dependent Clp protease ATP-binding subunit ClpX compare
BWI76_RS16965 -2.0 -2.4 murein lipoprotein compare
BWI76_RS21480 -1.9 -2.5 phospho-2-dehydro-3-deoxyheptonate aldolase compare
BWI76_RS27310 -1.9 -6.6 glycosyltransferase compare
BWI76_RS26470 -1.9 -7.4 4-deoxy-4-formamido-L-arabinose- phosphoundecaprenol deformylase compare
BWI76_RS25960 -1.9 -4.4 NUDIX hydrolase compare
BWI76_RS01545 -1.8 -2.9 thiamine biosynthesis protein ThiS compare
BWI76_RS00025 -1.8 -1.3 hypothetical protein compare
BWI76_RS25070 -1.8 -2.1 hypothetical protein compare
BWI76_RS19375 -1.8 -2.4 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase compare
BWI76_RS05235 -1.8 -1.8 hypothetical protein compare
BWI76_RS15110 -1.8 -9.4 putative excinuclease ABC subunit A compare
BWI76_RS22700 -1.7 -4.7 sulfate adenylyltransferase subunit 2 compare
BWI76_RS01350 -1.7 -1.5 NAD(P)H-flavin reductase compare
BWI76_RS09635 -1.7 -2.5 amino acid ABC transporter ATP-binding protein compare
BWI76_RS25300 -1.6 -2.5 hybrid sensor histidine kinase/response regulator compare
BWI76_RS08520 -1.6 -1.7 colicin transporter TolQ compare
BWI76_RS01185 -1.6 -2.4 adenylate cyclase compare
BWI76_RS22695 -1.6 -3.5 sulfate adenylyltransferase compare
BWI76_RS11900 -1.6 -1.6 cob(I)yrinic acid a,c-diamide adenosyltransferase compare
BWI76_RS13915 -1.5 -2.9 magnesium transport protein MgtC compare
BWI76_RS15840 -1.5 -2.1 prophage protein compare
BWI76_RS21360 -1.5 -5.2 L-aspartate oxidase compare
BWI76_RS00390 -1.5 -3.3 two-component system sensor histidine kinase NtrB compare
BWI76_RS26075 -1.5 -2.4 DNA adenine methylase compare
BWI76_RS04715 -1.5 -1.8 division/cell wall cluster transcriptional repressor MraZ compare
BWI76_RS19600 -1.5 -5.6 hypothetical protein compare
BWI76_RS20900 -1.5 -1.9 outer membrane protein assembly factor BamC compare
BWI76_RS24025 -1.5 -5.6 agmatinase compare
BWI76_RS21140 -1.5 -2.7 molecular chaperone HscA compare
BWI76_RS17370 -1.4 -2.4 nitrate transporter NasD compare
BWI76_RS25600 -1.4 -1.2 tRNA-Thr compare
BWI76_RS21310 -1.4 -1.2 DNA repair protein RecO compare
BWI76_RS25425 -1.4 -1.3 arginine repressor compare
BWI76_RS26395 -1.4 -2.5 cell division protein FtsE compare
BWI76_RS09650 -1.3 -5.6 hypothetical protein compare
BWI76_RS00355 -1.3 -2.2 DNA polymerase I compare
BWI76_RS00970 -1.3 -1.5 branched chain amino acid aminotransferase compare
BWI76_RS05120 -1.2 -7.9 bifunctional glycosyl transferase/transpeptidase compare
BWI76_RS13820 -1.2 -2.2 hypothetical protein compare
BWI76_RS27290 -1.2 -5.8 hypothetical protein compare
BWI76_RS25870 -1.2 -1.9 elongation factor Tu compare
BWI76_RS21580 -1.2 -1.5 SsrA-binding protein compare
BWI76_RS25505 -1.2 -4.5 RNase E specificity factor CsrD compare
BWI76_RS18165 -1.2 -1.8 NUDIX pyrophosphatase compare
BWI76_RS23885 -1.2 -1.7 2-octaprenylphenol hydroxylase compare
BWI76_RS27820 -1.2 -1.3 ilvB operon leader peptide IvbL compare
BWI76_RS25280 -1.2 -2.1 RNase adaptor protein RapZ compare
BWI76_RS09870 -1.2 -6.5 aromatic amino acid aminotransferase compare
BWI76_RS00875 -1.2 -3.4 DNA-binding transcriptional regulator FabR compare
BWI76_RS06770 -1.2 -5.8 Hha toxicity attenuator compare
BWI76_RS01205 -1.2 -2.1 DUF484 family protein compare
BWI76_RS20380 -1.1 -1.3 tRNA pseudouridine(38-40) synthase TruA compare
BWI76_RS13595 -1.1 -2.4 transcriptional regulator compare
BWI76_RS06185 -1.1 -5.5 shikimate kinase II compare
BWI76_RS26390 -1.1 -2.5 cell division protein FtsX compare
BWI76_RS03595 -1.1 -1.6 ethanolamine utilization protein EutM compare
BWI76_RS01925 -1.1 -5.6 aromatic amino acid aminotransferase compare
BWI76_RS20970 -1.1 -1.5 phosphoribosylglycinamide formyltransferase compare
BWI76_RS24075 -1.1 -3.2 glutathione synthase compare
BWI76_RS11040 -1.1 -2.6 ribonuclease E compare
BWI76_RS09730 -1.1 -1.5 pyruvate formate lyase 1-activating protein compare
BWI76_RS05260 -1.1 -1.5 chaperone compare
BWI76_RS22450 -1.0 -2.7 selenoprotein W-related protein compare
BWI76_RS21450 -1.0 -2.9 23S rRNA pseudouridine(1911/1915/1917) synthase compare
BWI76_RS07985 -1.0 -1.1 fluoride ion transporter CrcB compare
BWI76_RS09960 -1.0 -0.9 Lon protease compare


Specific Phenotypes

For 3 genes in this experiment

For carbon source D-Glucose in Klebsiella michiganensis M5al

For carbon source D-Glucose across organisms