Experiment set8IT018 for Methanococcus maripaludis S2

Compare to:

Mc formate, casamino free, with 10mM L-Proline

200 most important genes:

  gene name fitness t score description  
MMP_RS07345 -4.6 -9.9 glycine synthesis protein GlyXL (from data) compare
MMP_RS05550 -4.0 -0.7 cation:proton antiporter compare
MMP_RS01175 -4.0 -5.6 triphosphoribosyl-dephospho-CoA synthase compare
MMP_RS06350 -3.9 -8.0 HesA/MoeB/ThiF family protein compare
MMP_RS06355 -3.6 -2.9 molybdenum cofactor biosynthesis protein MoaE compare
MMP_RS03015 -3.5 -11.1 GTP 3' 8-cyclase MoaA compare
MMP_RS06680 -3.4 -18.6 Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain compare
MMP_RS01195 -3.3 -1.5 metalloregulator ArsR/SmtB family transcription factor compare
MMP_RS06685 -3.3 -16.3 formate dehydrogenase H subunit alpha selenocysteine-containing compare
MMP_RS01545 -3.1 -1.3 CBS domain-containing protein compare
MMP_RS06700 -3.1 -14.2 hypothetical protein compare
MMP_RS05515 -3.1 -7.5 cyclic pyranopterin monophosphate synthase MoaC compare
MMP_RS06345 -3.0 -14.2 formate dehydrogenase accessory sulfurtransferase FdhD compare
MMP_RS06720 -3.0 -9.3 response regulator transcription factor compare
MMP_RS04605 -3.0 -6.6 cobalt ECF transporter T component CbiQ compare
MMP_RS01085 -2.9 -2.1 hypothetical protein compare
MMP_RS06715 -2.9 -17.7 cache domain-containing protein compare
MMP_RS07635 -2.9 -9.9 MogA/MoaB family molybdenum cofactor biosynthesis protein compare
MMP_RS06840 -2.9 -1.1 DNA-directed RNA polymerase subunit N compare
MMP_RS04900 -2.8 -21.4 hypothetical protein compare
MMP_RS05875 -2.8 -6.7 hydroxyethylthiazole kinase compare
MMP_RS05500 -2.8 -9.6 2-isopropylmalate synthase compare
MMP_RS01385 -2.7 -0.6 imidazole glycerol phosphate synthase subunit HisH compare
MMP_RS06705 -2.7 -7.2 formate/nitrite transporter family protein compare
MMP_RS03450 -2.7 -2.5 glycine synthesis protein GlyXS (from data) compare
MMP_RS01500 -2.7 -3.2 CBS domain-containing protein compare
MMP_RS07730 -2.6 -2.0 pyruvate synthase subunit beta compare
MMP_RS03435 -2.6 -2.1 ketol-acid reductoisomerase compare
MMP_RS08165 -2.6 -3.0 phosphoglycerate dehydrogenase compare
MMP_RS07365 -2.6 -13.9 2-phosphoglycerate kinase compare
MMP_RS08940 -2.5 -1.2 MetS family NSS transporter small subunit compare
MMP_RS01005 -2.5 -1.6 riboflavin synthase compare
MMP_RS00040 -2.5 -7.4 TIGR03576 family pyridoxal phosphate-dependent enzyme compare
MMP_RS09055 -2.4 -1.3 CAP domain-containing protein compare
MMP_RS08745 -2.4 -6.7 CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase compare
MMP_RS05930 -2.4 -2.9 3-isopropylmalate dehydratase large subunit compare
MMP_RS07630 -2.3 -1.5 ATP-binding cassette domain-containing protein compare
MMP_RS02010 -2.3 -9.7 PHP domain-containing protein compare
MMP_RS07735 -2.3 -0.9 2-ketoisovalerate ferredoxin oxidoreductase subunit alpha compare
MMP_RS07445 -2.3 -7.0 helix-turn-helix domain-containing protein compare
MMP_RS04620 -2.3 -10.9 cobalt transporter CbiM compare
MMP_RS01985 -2.3 -5.2 F420-dependent methylenetetrahydromethanopterin dehydrogenase compare
MMP_RS07845 -2.2 -2.2 LL-diaminopimelate aminotransferase compare
MMP_RS03035 -2.2 -4.0 4-hydroxy-tetrahydrodipicolinate synthase compare
MMP_RS01755 -2.2 -1.6 DUF2097 domain-containing protein compare
MMP_RS04615 -2.2 -3.2 PDGLE domain-containing protein compare
MMP_RS03640 -2.2 -4.7 archaeal proteasome endopeptidase complex subunit beta compare
MMP_RS09020 -2.2 -1.8 hypothetical protein compare
MMP_RS07525 -2.2 -8.9 4Fe-4S binding protein compare
MMP_RS05425 -2.1 -4.9 monovalent cation/H+ antiporter complex subunit F compare
MMP_RS05765 -2.1 -7.1 M42 family metallopeptidase compare
MMP_RS06175 -2.0 -6.2 winged helix-turn-helix transcriptional regulator compare
MMP_RS01020 -2.0 -1.2 3 4-dihydroxy-2-butanone-4-phosphate synthase compare
MMP_RS03025 -2.0 -6.2 molybdenum cofactor guanylyltransferase compare
MMP_RS05085 -2.0 -7.8 AAA family ATPase compare
MMP_RS06105 -2.0 -7.1 hydrogenase maturation peptidase HycI compare
MMP_RS07185 -1.9 -12.1 pyridoxal phosphate-dependent aminotransferase compare
MMP_RS07555 -1.9 -0.8 monovalent cation/H+ antiporter subunit E compare
MMP_RS05095 -1.9 -5.3 CO dehydrogenase/acetyl-CoA synthase complex subunit epsilon compare
MMP_RS03315 -1.9 -1.2 ferrous iron transport protein A compare
MMP_RS08720 -1.9 -1.8 4Fe-4S binding protein compare
MMP_RS07575 -1.9 -3.7 RNA ligase partner protein compare
MMP_RS05090 -1.9 -8.1 CO dehydrogenase/CO-methylating acetyl-CoA synthase complex subunit beta compare
MMP_RS01380 -1.9 -4.5 PHP domain-containing protein compare
MMP_RS05060 -1.8 -8.2 AAA family ATPase compare
MMP_RS01440 -1.8 -4.5 NAAT family transporter compare
MMP_RS06925 -1.8 -2.7 ribonuclease VapC4 compare
MMP_RS05080 -1.8 -10.2 acetyl-CoA decarbonylase/synthase complex subunit delta compare
MMP_RS00685 -1.8 -3.8 2-phospho-L-lactate guanylyltransferase compare
MMP_RS00305 -1.8 -2.1 phosphoribosyl-ATP diphosphatase compare
MMP_RS02355 -1.8 -2.7 30S ribosomal protein S27ae compare
MMP_RS05055 -1.8 -11.4 DUF166 domain-containing protein compare
MMP_RS08635 -1.7 -1.8 UbiA family prenyltransferase compare
MMP_RS00695 -1.7 -1.1 biotin--[acetyl-CoA-carboxylase] ligase compare
MMP_RS04870 -1.7 -5.4 TIGR02253 family HAD-type hydrolase compare
MMP_RS04125 -1.7 -3.0 TetR/AcrR family transcriptional regulator compare
MMP_RS05100 -1.7 -11.1 CO dehydrogenase/acetyl-CoA synthase complex subunit alpha compare
MMP_RS06295 -1.7 -6.5 methanogenesis marker 14 protein compare
MMP_RS08330 -1.6 -5.8 NADH-quinone oxidoreductase subunit H compare
MMP_RS02800 -1.6 -3.9 nucleotidyltransferase domain-containing protein compare
MMP_RS05540 -1.6 -2.4 hypothetical protein compare
MMP_RS05075 -1.6 -10.2 acetyl-CoA decarbonylase/synthase complex subunit gamma compare
MMP_RS08615 -1.6 -1.3 flagellar protein G compare
MMP_RS00620 -1.6 -6.2 4Fe-4S binding protein compare
MMP_RS00295 -1.6 -2.0 gamma carbonic anhydrase family protein compare
MMP_RS08460 -1.5 -2.6 proteasome-activating nucleotidase compare
MMP_RS06200 -1.5 -5.5 M24 family metallopeptidase compare
MMP_RS02195 -1.5 -3.4 tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase compare
MMP_RS05070 -1.5 -6.9 4Fe-4S dicluster domain-containing protein compare
MMP_RS03445 -1.5 -0.9 methanogenesis marker 17 protein compare
MMP_RS01220 -1.5 -5.9 hypothetical protein compare
MMP_RS00300 -1.4 -0.7 6 7-dimethyl-8-ribityllumazine synthase compare
MMP_RS03550 -1.4 -1.6 DUF2124 domain-containing protein compare
MMP_RS07005 -1.4 -0.5 4Fe-4S binding protein compare
MMP_RS01610 -1.4 -2.3 hypothetical protein compare
MMP_RS06485 -1.4 -1.0 zinc ribbon domain-containing protein compare
MMP_RS05065 -1.4 -4.3 CooT family nickel-binding protein compare
MMP_RS04090 -1.4 -2.6 hypothetical protein compare
MMP_RS06625 -1.3 -1.8 DNA primase compare
MMP_RS05555 -1.3 -1.1 DUF4040 domain-containing protein compare
MMP_RS06975 -1.3 -1.9 sulfide-dependent adenosine diphosphate thiazole synthase compare
MMP_RS03080 -1.3 -1.9 universal stress protein compare
MMP_RS08715 -1.3 -1.6 formylmethanofuran dehydrogenase subunit B compare
MMP_RS08790 -1.3 -1.4 translation initiation factor IF-2 subunit alpha compare
MMP_RS03600 -1.3 -1.7 triose-phosphate isomerase compare
MMP_RS01795 -1.3 -1.3 methanogenesis marker 6 protein compare
MMP_RS08300 -1.3 -0.8 metal-sulfur cluster assembly factor compare
MMP_RS04255 -1.3 -3.4 coenzyme F420 hydrogenase subunit beta compare
MMP_RS07710 -1.3 -4.8 cell division protein FtsZ compare
MMP_RS01075 -1.2 -1.2 hypothetical protein compare
MMP_RS01265 -1.2 -1.6 hypothetical protein compare
MMP_RS02340 -1.2 -1.0 DNA-directed RNA polymerase subunit E'' compare
MMP_RS03305 -1.2 -4.0 winged helix-turn-helix domain-containing protein compare
MMP_RS07380 -1.2 -1.6 transcription elongation factor Spt5 compare
MMP_RS01365 -1.2 -2.6 archaeal proteasome endopeptidase complex subunit alpha compare
MMP_RS00535 -1.2 -1.9 TIGR00375 family protein compare
MMP_RS04875 -1.2 -2.8 energy-converting hydrogenase B subunit P compare
MMP_RS01830 -1.2 -1.3 tRNA-Val compare
MMP_RS06400 -1.2 -1.3 4Fe-4S binding protein compare
MMP_RS07705 -1.1 -3.7 transcriptional regulator compare
MMP_RS05440 -1.1 -5.4 winged helix-turn-helix transcriptional regulator compare
MMP_RS00290 -1.1 -4.6 hypothetical protein compare
MMP_RS02885 -1.1 -6.7 molybdopterin biosynthesis protein compare
MMP_RS00555 -1.1 -3.6 MFS transporter compare
MMP_RS04780 -1.1 -2.5 ribonuclease P compare
MMP_RS02235 -1.1 -3.5 CBS domain-containing protein compare
MMP_RS01240 -1.1 -1.2 7-cyano-7-deazaguanine synthase QueC compare
MMP_RS05265 -1.1 -1.5 2-isopropylmalate synthase compare
MMP_RS01445 -1.1 -3.4 hypothetical protein compare
MMP_RS08320 -1.1 -4.4 molybdopterin molybdotransferase MoeA compare
MMP_RS01790 -1.1 -2.6 restriction endonuclease compare
MMP_RS07720 -1.1 -5.0 4Fe-4S binding protein compare
MMP_RS02280 -1.1 -0.7 DUF211 domain-containing protein compare
MMP_RS03485 -1.1 -3.0 TIGR00267 family protein compare
MMP_RS04890 -1.1 -0.6 adenylyltransferase/cytidyltransferase family protein compare
MMP_RS00130 -1.0 -0.8 nickel-responsive transcriptional regulator NikR compare
MMP_RS08645 -1.0 -3.9 UPF0179 family protein compare
MMP_RS04410 -1.0 -1.4 hypothetical protein compare
MMP_RS07415 -1.0 -2.5 molybdopterin-guanine dinucleotide biosynthesis protein MobB compare
MMP_RS06340 -1.0 -4.1 phosphoadenosine phosphosulfate reductase family protein compare
MMP_RS03145 -1.0 -3.8 fibrillarin-like rRNA/tRNA 2'-O-methyltransferase compare
MMP_RS08820 -1.0 -3.7 hypothetical protein compare
MMP_RS05850 -1.0 -2.1 Ldh family oxidoreductase compare
MMP_RS01325 -1.0 -1.4 dihydroneopterin aldolase family protein compare
MMP_RS05505 -1.0 -4.7 class IV adenylate cyclase compare
MMP_RS02610 -0.9 -2.5 DUF2162 domain-containing protein compare
MMP_RS05865 -0.9 -1.0 hypothetical protein compare
MMP_RS03960 -0.9 -0.8 hypothetical protein compare
MMP_RS04055 -0.9 -1.1 hypothetical protein compare
MMP_RS06870 -0.9 -3.1 DedA family protein compare
MMP_RS01800 -0.9 -2.1 TIGR00303 family protein compare
MMP_RS06895 -0.9 -0.9 selenocysteine-specific translation elongation factor compare
MMP_RS06630 -0.9 -0.7 UPF0058 family protein compare
MMP_RS07535 -0.9 -4.2 4Fe-4S binding protein compare
MMP_RS00720 -0.9 -3.2 metal-dependent hydrolase compare
MMP_RS02165 -0.9 -3.0 tRNA-dihydrouridine synthase compare
MMP_RS08750 -0.9 -1.2 hypothetical protein compare
MMP_RS07605 -0.9 -2.1 diadenylate cyclase compare
MMP_RS06325 -0.9 -0.9 hypothetical protein compare
MMP_RS05925 -0.9 -2.2 small nuclear ribonucleoprotein compare
MMP_RS04585 -0.9 -5.1 AIR synthase related protein compare
MMP_RS05985 -0.8 -0.9 hypothetical protein compare
MMP_RS01720 -0.8 -1.1 replication factor C large subunit compare
MMP_RS06285 -0.8 -1.4 precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT compare
MMP_RS06865 -0.8 -1.2 HypC/HybG/HupF family hydrogenase formation chaperone compare
MMP_RS06020 -0.8 -2.5 archaeoflavoprotein AfpA compare
MMP_RS07960 -0.8 -3.8 sugar phosphate isomerase/epimerase compare
MMP_RS00455 -0.8 -3.0 orotate phosphoribosyltransferase-like protein compare
MMP_RS00655 -0.8 -1.2 hypothetical protein compare
MMP_RS00345 -0.8 -2.1 DUF2666 domain-containing protein compare
MMP_RS03140 -0.8 -3.9 hypothetical protein compare
MMP_RS02930 -0.8 -1.2 class I SAM-dependent methyltransferase compare
MMP_RS02170 -0.8 -2.4 CBS domain-containing protein compare
MMP_RS01260 -0.8 -2.4 HDIG domain-containing protein compare
MMP_RS00570 -0.8 -0.8 protein-L-isoaspartate O-methyltransferase compare
MMP_RS00060 -0.8 -1.2 3-dehydroquinate synthase II compare
MMP_RS00965 -0.8 -0.9 hypothetical protein compare
MMP_RS06215 -0.8 -1.1 30S ribosomal protein S6e compare
MMP_RS07200 -0.7 -2.9 [5-(aminomethyl)furan-3-yl]methyl phosphate kinase compare
MMP_RS01225 -0.7 -2.6 DUF5379 domain-containing protein compare
MMP_RS05845 -0.7 -0.9 tRNA-intron lyase compare
MMP_RS02240 -0.7 -2.0 methanogenesis marker 7 protein compare
MMP_RS08725 -0.7 -1.1 Ni/Fe hydrogenase subunit alpha compare
MMP_RS03475 -0.7 -0.4 hypothetical protein compare
MMP_RS03585 -0.7 -1.9 Hsp20/alpha crystallin family protein compare
MMP_RS02975 -0.7 -1.8 DUF2124 domain-containing protein compare
MMP_RS02045 -0.7 -0.9 tRNA-Met compare
MMP_RS05910 -0.7 -1.0 cell division ATPase MinD compare
MMP_RS04990 -0.7 -2.4 aquaporin family protein compare
MMP_RS02345 -0.7 -1.5 GTP-dependent dephospho-CoA kinase family protein compare
MMP_RS05250 -0.7 -0.9 NFYB/HAP3 family transcription factor subunit compare
MMP_RS01255 -0.7 -1.2 amino acid ABC transporter ATP-binding protein compare
MMP_RS05245 -0.7 -2.7 archaeosine biosynthesis radical SAM protein RaSEA compare
MMP_RS05285 -0.7 -2.7 MMPL family transporter compare
MMP_RS03465 -0.7 -0.6 adenine phosphoribosyltransferase compare
MMP_RS06730 -0.7 -0.6 phosphopantothenate/pantothenate synthetase compare
MMP_RS01140 -0.7 -1.2 molybdate ABC transporter permease subunit compare
MMP_RS03685 -0.7 -2.7 Mrp/NBP35 family ATP-binding protein compare
MMP_RS00705 -0.7 -1.2 hypothetical protein compare
MMP_RS05975 -0.7 -0.7 hypothetical protein compare


Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in nutrient t1 experiments

For nutrient t1 L-Proline across organisms