Experiment set8IT016 for Pseudomonas fluorescens FW300-N2E2

Compare to:

D-Alanine nitrogen source

200 most important genes:

  gene name fitness t score description  
Pf6N2E2_4826 -6.9 -4.7 Indole-3-glycerol phosphate synthase (EC 4.1.1.48) compare
Pf6N2E2_4597 -6.7 -4.6 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_71 -6.6 -4.6 Phosphoribosylanthranilate isomerase (EC 5.3.1.24) compare
Pf6N2E2_3630 -6.5 -4.5 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_3248 -6.5 -6.3 Probable transmembrane protein compare
Pf6N2E2_3783 -6.4 -4.4 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
Pf6N2E2_3842 -6.4 -4.4 Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) compare
Pf6N2E2_4825 -6.0 -7.2 Anthranilate phosphoribosyltransferase (EC 2.4.2.18) compare
Pf6N2E2_5006 -6.0 -5.9 Muramoyltetrapeptide carboxypeptidase (EC 3.4.17.13) compare
Pf6N2E2_3782 -5.7 -4.0 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) compare
Pf6N2E2_3253 -5.7 -5.6 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
Pf6N2E2_3751 -5.7 -13.3 Glutamate synthase [NADPH] small chain (EC 1.4.1.13) compare
Pf6N2E2_5175 -5.7 -13.2 Acetolactate synthase large subunit (EC 2.2.1.6) compare
Pf6N2E2_4279 -5.6 -13.0 Pyruvate carboxyl transferase subunit B (EC 6.4.1.1) compare
Pf6N2E2_4047 -5.5 -5.3 Tryptophan synthase alpha chain (EC 4.2.1.20) compare
Pf6N2E2_4596 -5.4 -10.9 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_64 -5.2 -4.9 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) compare
Pf6N2E2_77 -5.2 -6.1 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) compare
Pf6N2E2_3752 -5.1 -23.4 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) compare
Pf6N2E2_50 -5.1 -10.3 Biosynthetic Aromatic amino acid aminotransferase alpha (EC 2.6.1.57) @ Aromatic-amino-acid aminotransferase (EC 2.6.1.57) compare
Pf6N2E2_2073 -5.1 -6.0 Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2) compare
Pf6N2E2_3940 -5.0 -13.3 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_3839 -5.0 -4.8 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
Pf6N2E2_5176 -4.9 -12.2 Acetolactate synthase small subunit (EC 2.2.1.6) compare
Pf6N2E2_4759 -4.9 -18.3 Biotin synthase (EC 2.8.1.6) compare
Pf6N2E2_5177 -4.8 -12.6 Ketol-acid reductoisomerase (EC 1.1.1.86) compare
Pf6N2E2_4564 -4.8 -9.7 Dihydroxy-acid dehydratase (EC 4.2.1.9) compare
Pf6N2E2_2885 -4.7 -5.6 Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) compare
Pf6N2E2_3610 -4.7 -6.3 ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) compare
Pf6N2E2_4278 -4.7 -14.9 Pyruvate carboxyl transferase subunit A (EC 6.4.1.1) compare
Pf6N2E2_4048 -4.4 -7.3 Tryptophan synthase beta chain (EC 4.2.1.20) compare
Pf6N2E2_3932 -4.2 -5.4 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) compare
Pf6N2E2_5156 -4.0 -2.8 Two-component sensor CbrB: intrcellular carbon:nitrogen balance compare
Pf6N2E2_2258 -4.0 -14.6 Transaldolase (EC 2.2.1.2) compare
Pf6N2E2_4638 -4.0 -2.8 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) compare
Pf6N2E2_4743 -4.0 -1.8 hypothetical protein compare
Pf6N2E2_3252 -4.0 -7.7 Histidinol dehydrogenase (EC 1.1.1.23) compare
Pf6N2E2_66 -3.9 -8.2 3-isopropylmalate dehydrogenase (EC 1.1.1.85) compare
Pf6N2E2_3826 -3.8 -8.0 Nitrogen regulation protein NR(I) compare
Pf6N2E2_3251 -3.8 -13.1 histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) compare
Pf6N2E2_4187 -3.8 -5.1 Lipid A biosynthesis lauroyl acyltransferase (EC 2.3.1.-) compare
Pf6N2E2_4390 -3.8 -11.1 Leucine-responsive regulatory protein, regulator for leucine (or lrp) regulon and high-affinity branched-chain amino acid transport system conserved
Pf6N2E2_4391 -3.7 -8.3 D-amino acid dehydrogenase small subunit (EC 1.4.99.1) compare
Pf6N2E2_4277 -3.6 -9.4 LysR family transcriptional regulator PA5437 compare
Pf6N2E2_5544 -3.5 -11.3 TPR repeat containing exported protein; Putative periplasmic protein contains a protein prenylyltransferase domain compare
Pf6N2E2_302 -3.4 -6.8 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) compare
Pf6N2E2_4764 -3.4 -9.3 Dethiobiotin synthetase (EC 6.3.3.3) compare
Pf6N2E2_2074 -3.4 -2.1 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) compare
Pf6N2E2_3841 -3.2 -4.7 Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) compare
Pf6N2E2_4761 -3.2 -12.2 8-amino-7-oxononanoate synthase (EC 2.3.1.47) compare
Pf6N2E2_4206 -3.2 -3.0 Chromosome (plasmid) partitioning protein ParB compare
Pf6N2E2_4763 -3.2 -11.2 Biotin synthesis protein BioC compare
Pf6N2E2_4631 -3.2 -9.7 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62) compare
Pf6N2E2_4762 -3.2 -2.6 Biotin synthesis protein BioH compare
Pf6N2E2_3825 -3.1 -5.0 Nitrogen regulation protein NtrB (EC 2.7.13.3) compare
Pf6N2E2_5527 -3.0 -3.4 Cold shock protein CspC compare
Pf6N2E2_5316 -2.9 -3.3 Periplasmic thiol:disulfide oxidoreductase DsbB, required for DsbA reoxidation compare
Pf6N2E2_3170 -2.9 -7.1 2-isopropylmalate synthase (EC 2.3.3.13) compare
Pf6N2E2_2513 -2.8 -5.5 UDP-glucose dehydrogenase (EC 1.1.1.22) compare
Pf6N2E2_2465 -2.8 -5.3 Cys regulon transcriptional activator CysB compare
Pf6N2E2_3941 -2.8 -3.7 Adenosine (5')-pentaphospho-(5'')-adenosine pyrophosphohydrolase (EC 3.6.1.-) compare
Pf6N2E2_5150 -2.7 -7.5 Glucose-6-phosphate isomerase (EC 5.3.1.9) compare
Pf6N2E2_2897 -2.7 -12.8 Glucokinase (EC 2.7.1.2) compare
Pf6N2E2_5728 -2.6 -6.2 Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) compare
Pf6N2E2_5579 -2.5 -7.3 Ornithine carbamoyltransferase (EC 2.1.3.3) compare
Pf6N2E2_5258 -2.5 -9.3 Sulfate adenylyltransferase subunit 1 (EC 2.7.7.4) / Adenylylsulfate kinase (EC 2.7.1.25) compare
Pf6N2E2_2899 -2.5 -6.3 NAD-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12) compare
Pf6N2E2_63 -2.4 -3.6 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) compare
Pf6N2E2_3938 -2.3 -14.3 Threonine dehydratase biosynthetic (EC 4.3.1.19) compare
Pf6N2E2_5190 -2.3 -12.6 Carbonic anhydrase (EC 4.2.1.1) compare
Pf6N2E2_5950 -2.3 -5.8 Phosphate:acyl-ACP acyltransferase PlsX compare
Pf6N2E2_3984 -2.2 -10.7 T1SS associated transglutaminase-like cysteine proteinase LapP compare
Pf6N2E2_51 -2.2 -7.2 hypothetical protein compare
Pf6N2E2_2864 -2.2 -3.4 Gluconokinase (EC 2.7.1.12) compare
Pf6N2E2_4009 -2.2 -10.9 GGDEF domain protein compare
Pf6N2E2_5014 -2.2 -2.0 Apolipoprotein N-acyltransferase (EC 2.3.1.-) / Copper homeostasis protein CutE compare
Pf6N2E2_5257 -2.1 -9.1 Sulfate adenylyltransferase subunit 2 (EC 2.7.7.4) compare
Pf6N2E2_2753 -2.1 -3.9 HtrA protease/chaperone protein compare
Pf6N2E2_4204 -2.1 -2.4 rRNA small subunit 7-methylguanosine (m7G) methyltransferase GidB compare
Pf6N2E2_5676 -2.1 -6.4 Aspartokinase (EC 2.7.2.4) compare
Pf6N2E2_1718 -2.1 -5.0 Anthranilate synthase, amidotransferase component (EC 4.1.3.27) compare
Pf6N2E2_2510 -2.0 -4.3 Lipid carrier : UDP-N-acetylgalactosaminyltransferase (EC 2.4.1.-) / Alpha-1,3-N-acetylgalactosamine transferase PglA (EC 2.4.1.-); Putative glycosyltransferase compare
Pf6N2E2_5001 -2.0 -2.3 D-alanyl-D-alanine carboxypeptidase (EC 3.4.16.4) compare
Pf6N2E2_5816 -2.0 -2.4 Smr domain protein compare
Pf6N2E2_4797 -2.0 -3.2 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase (EC 2.7.6.3) compare
Pf6N2E2_5103 -2.0 -1.2 Glutamate 5-kinase (EC 2.7.2.11) / RNA-binding C-terminal domain PUA compare
Pf6N2E2_4352 -1.9 -3.5 ATP-dependent DNA helicase RecG (EC 3.6.1.-) compare
Pf6N2E2_3942 -1.9 -9.7 FIG001592: Phosphocarrier protein kinase/phosphorylase, nitrogen regulation associated compare
Pf6N2E2_4276 -1.9 -6.6 Phosphogluconate repressor HexR, RpiR family compare
Pf6N2E2_2218 -1.9 -5.2 ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92) compare
Pf6N2E2_4416 -1.8 -3.4 Tyrosine recombinase XerC compare
Pf6N2E2_1886 -1.7 -1.5 hypothetical protein compare
Pf6N2E2_3060 -1.7 -4.3 Outer membrane protein H precursor compare
Pf6N2E2_5666 -1.7 -8.3 Arginine N-succinyltransferase, alpha subunit (EC 2.3.1.109) compare
Pf6N2E2_3908 -1.7 -6.3 Glutamate--cysteine ligase (EC 6.3.2.2) compare
Pf6N2E2_4372 -1.6 -5.0 FIG00460773: hypothetical protein compare
Pf6N2E2_4987 -1.6 -1.8 MaoC-like domain protein compare
Pf6N2E2_2059 -1.6 -3.1 ChlI component of cobalt chelatase involved in B12 biosynthesis compare
Pf6N2E2_3072 -1.6 -8.5 [Protein-PII] uridylyltransferase (EC 2.7.7.59) compare
Pf6N2E2_2261 -1.6 -7.0 VacJ-like lipoprotein precursor compare
Pf6N2E2_2586 -1.6 -2.1 Hpt domain protein compare
Pf6N2E2_70 -1.5 -3.9 tRNA pseudouridine synthase A (EC 4.2.1.70) compare
Pf6N2E2_3258 -1.5 -4.6 Uncharacterized ABC transporter, periplasmic component YrbD compare
Pf6N2E2_5667 -1.5 -6.4 Arginine N-succinyltransferase (EC 2.3.1.109) compare
Pf6N2E2_2473 -1.5 -1.7 Major outer membrane lipoprotein I compare
Pf6N2E2_3820 -1.5 -2.2 hypothetical protein compare
Pf6N2E2_4072 -1.4 -5.0 Phosphate transport ATP-binding protein PstB (TC 3.A.1.7.1) compare
Pf6N2E2_2574 -1.4 -2.2 Flagellar synthesis regulator FleN compare
Pf6N2E2_658 -1.4 -7.8 sensor histidine kinase compare
Pf6N2E2_3349 -1.4 -3.7 Polyribonucleotide nucleotidyltransferase (EC 2.7.7.8) compare
Pf6N2E2_3300 -1.4 -3.7 Predicted D-glucarate or D-galactorate regulator, GntR family compare
Pf6N2E2_5739 -1.4 -2.2 Cobalamin biosynthesis protein BluB @ 5,6-dimethylbenzimidazole synthase, flavin destructase family compare
Pf6N2E2_3198 -1.4 -2.1 tRNA-guanine transglycosylase (EC 2.4.2.29) compare
Pf6N2E2_2217 -1.4 -4.6 ATP-dependent Clp protease ATP-binding subunit ClpX compare
Pf6N2E2_4453 -1.3 -10.5 Polyphosphate kinase (EC 2.7.4.1) compare
Pf6N2E2_2186 -1.3 -4.9 Isovaleryl-CoA dehydrogenase (EC 1.3.8.4) compare
Pf6N2E2_5520 -1.3 -4.9 Sensory box histidine kinase compare
Pf6N2E2_3260 -1.3 -4.7 Uncharacterized ABC transporter, ATP-binding protein YrbF compare
Pf6N2E2_1545 -1.3 -4.0 N-carbamoylputrescine amidase (EC 3.5.1.53) compare
Pf6N2E2_1694 -1.3 -1.6 FMN reductase (EC 1.5.1.29) compare
Pf6N2E2_623 -1.3 -1.9 FIG00954674: hypothetical protein compare
Pf6N2E2_5613 -1.3 -2.4 FIG00953674: hypothetical protein compare
Pf6N2E2_2827 -1.3 -1.8 hypothetical protein compare
Pf6N2E2_5745 -1.3 -6.0 Alpha-ribazole-5'-phosphate phosphatase (EC 3.1.3.73) compare
Pf6N2E2_2072 -1.2 -2.7 hypothetical protein compare
Pf6N2E2_2487 -1.2 -1.2 FIG00956090: hypothetical protein compare
Pf6N2E2_4479 -1.2 -1.8 FIG001590: Putative conserved exported protein precursor compare
Pf6N2E2_5337 -1.2 -5.0 Ubiquinol-cytochrome C reductase iron-sulfur subunit (EC 1.10.2.2) compare
Pf6N2E2_4205 -1.2 -3.0 Chromosome (plasmid) partitioning protein ParA compare
Pf6N2E2_2065 -1.2 -3.1 Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133) compare
Pf6N2E2_2674 -1.2 -1.3 FIG00953856: hypothetical protein compare
Pf6N2E2_5338 -1.2 -7.1 Ubiquinol--cytochrome c reductase, cytochrome B subunit (EC 1.10.2.2) compare
Pf6N2E2_6099 -1.2 -1.7 tRNA-Glu-TTC compare
Pf6N2E2_1182 -1.1 -4.0 Transcriptional regulator, LysR family compare
Pf6N2E2_3534 -1.1 -2.5 Cobalamin biosynthesis protein CobG compare
Pf6N2E2_3199 -1.1 -5.4 S-adenosylmethionine:tRNA ribosyltransferase-isomerase (EC 5.-.-.-) compare
Pf6N2E2_2320 -1.1 -2.9 Heavy-metal-associated domain (N-terminus) and membrane-bounded cytochrome biogenesis cycZ-like domain, possible membrane copper tolerance protein compare
Pf6N2E2_3039 -1.1 -4.8 Protein-L-isoaspartate O-methyltransferase (EC 2.1.1.77) compare
Pf6N2E2_1717 -1.1 -7.0 Anthranilate synthase, aminase component (EC 4.1.3.27) compare
Pf6N2E2_1932 -1.1 -5.0 Transcriptional regulator, IclR family compare
Pf6N2E2_3351 -1.1 -4.1 tRNA pseudouridine synthase B (EC 4.2.1.70) compare
Pf6N2E2_5723 -1.1 -7.4 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) compare
Pf6N2E2_2034 -1.1 -3.6 Methyltransferase compare
Pf6N2E2_469 -1.1 -2.7 lipoprotein, putative compare
Pf6N2E2_659 -1.1 -2.6 Transcriptional regulatory protein ompR compare
Pf6N2E2_613 -1.1 -1.6 lipoprotein, putative compare
Pf6N2E2_3786 -1.1 -3.0 Twin-arginine translocation protein TatC compare
Pf6N2E2_5843 -1.1 -1.3 hypothetical protein compare
Pf6N2E2_2313 -1.1 -3.2 Cytochrome c oxidase subunit CcoP (EC 1.9.3.1) compare
Pf6N2E2_16 -1.1 -1.8 hypothetical protein compare
Pf6N2E2_5679 -1.0 -2.7 hypothetical protein compare
Pf6N2E2_1606 -1.0 -4.0 Carboxynorspermidine decarboxylase, putative (EC 4.1.1.-) compare
Pf6N2E2_5242 -1.0 -2.0 Malate:quinone oxidoreductase (EC 1.1.5.4) compare
Pf6N2E2_6045 -1.0 -1.6 hypothetical protein compare
Pf6N2E2_4417 -1.0 -3.4 Protein of unknown function DUF484 compare
Pf6N2E2_5155 -1.0 -2.4 Poly(A) polymerase (EC 2.7.7.19) compare
Pf6N2E2_5546 -1.0 -5.4 Queuosine Biosynthesis QueC ATPase compare
Pf6N2E2_58 -1.0 -2.7 tRNA-dihydrouridine synthase C (EC 1.-.-.-) compare
Pf6N2E2_5705 -1.0 -1.5 Sensor protein PhoQ (EC 2.7.13.3) compare
Pf6N2E2_3537 -1.0 -3.2 Cobalt-precorrin-6x reductase (EC 1.3.1.54) compare
Pf6N2E2_2318 -1.0 -5.9 Type cbb3 cytochrome oxidase biogenesis protein CcoI; Copper-translocating P-type ATPase (EC 3.6.3.4) compare
Pf6N2E2_942 -1.0 -1.6 Mll6465 protein compare
Pf6N2E2_2514 -1.0 -3.4 regulator of length of O-antigen component of lipopolysaccharide chains compare
Pf6N2E2_5665 -1.0 -4.1 Succinylornithine transaminase (EC 2.6.1.81) compare
Pf6N2E2_1490 -1.0 -2.5 hypothetical protein compare
Pf6N2E2_5073 -1.0 -2.5 Large-conductance mechanosensitive channel compare
Pf6N2E2_2068 -1.0 -5.7 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13) compare
Pf6N2E2_5339 -1.0 -4.0 ubiquinol cytochrome C oxidoreductase, cytochrome C1 subunit compare
Pf6N2E2_3040 -1.0 -4.2 5-nucleotidase SurE (EC 3.1.3.5) compare
Pf6N2E2_3257 -1.0 -2.7 Uncharacterized ABC transporter, auxiliary component YrbC compare
Pf6N2E2_2890 -0.9 -5.9 Glucose ABC transport system, inner membrane component 2 compare
Pf6N2E2_2588 -0.9 -2.9 Anti-sigma F factor antagonist (spoIIAA-2); Anti-sigma B factor antagonist RsbV compare
Pf6N2E2_5252 -0.9 -1.8 FIG00956396: hypothetical protein compare
Pf6N2E2_5741 -0.9 -3.9 L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81) compare
Pf6N2E2_1116 -0.9 -1.4 Inosine-5'-monophosphate dehydrogenase (EC 1.1.1.205) compare
Pf6N2E2_75 -0.9 -2.2 Colicin V production protein compare
Pf6N2E2_2041 -0.9 -3.2 D-beta-hydroxybutyrate dehydrogenase (EC 1.1.1.30) compare
Pf6N2E2_3271 -0.9 -1.6 Phosphocarrier protein, nitrogen regulation associated compare
Pf6N2E2_3062 -0.9 -2.5 Membrane-associated zinc metalloprotease compare
Pf6N2E2_1396 -0.9 -0.9 ABC transporter, ATP-binding protein compare
Pf6N2E2_1056 -0.9 -0.4 Quinone oxidoreductase (EC 1.6.5.5) compare
Pf6N2E2_3283 -0.9 -4.0 Cytoplasmic axial filament protein CafA and Ribonuclease G (EC 3.1.4.-) compare
Pf6N2E2_1248 -0.9 -1.7 MutT/nudix family protein compare
Pf6N2E2_3532 -0.9 -4.0 Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130) compare
Pf6N2E2_3531 -0.9 -3.1 Cobalamin biosynthesis protein CbiG / Cobalt-precorrin-3b C17-methyltransferase compare
Pf6N2E2_84 -0.9 -1.2 hypothetical protein compare
Pf6N2E2_5494 -0.9 -2.2 Pyruvate kinase (EC 2.7.1.40) compare
Pf6N2E2_2274 -0.9 -3.5 Soluble pyridine nucleotide transhydrogenase (EC 1.6.1.1) compare
Pf6N2E2_5236 -0.9 -2.3 hypothetical protein compare
Pf6N2E2_3607 -0.9 -4.6 3'-to-5' exoribonuclease RNase R compare
Pf6N2E2_652 -0.9 -2.9 General secretion pathway protein E compare
Pf6N2E2_4071 -0.9 -3.4 Phosphate transport system regulatory protein PhoU compare
Pf6N2E2_4454 -0.9 -3.7 Exopolyphosphatase (EC 3.6.1.11) compare
Pf6N2E2_5986 -0.9 -1.4 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
Pf6N2E2_2889 -0.9 -5.2 Glucose ABC transporter, ATP-binding subunit (EC 3.6.3.-) compare
Pf6N2E2_1691 -0.8 -1.9 hypothetical protein compare
Pf6N2E2_4351 -0.8 -5.4 Predicted signal transduction protein compare
Pf6N2E2_3132 -0.8 -2.8 FIG00954548: hypothetical protein compare
Pf6N2E2_2340 -0.8 -3.4 Transcriptional regulator, GntR family compare
Pf6N2E2_1656 -0.8 -2.2 hypothetical protein compare


Specific Phenotypes

For 1 genes in this experiment

For nitrogen source D-Alanine in Pseudomonas fluorescens FW300-N2E2

For nitrogen source D-Alanine across organisms