Experiment set8IT016 for Methanococcus maripaludis S2

Compare to:

Mc formate, casamino free, with 10mM L-Proline

200 most detrimental genes:

  gene name fitness t score description  
MMP_RS02230 +3.1 18.1 sodium-dependent transporter compare
MMP_RS01370 +3.0 16.2 acetate--CoA ligase family protein compare
MMP_RS07115 +1.6 7.5 MBL fold metallo-hydrolase compare
MMP_RS07125 +1.6 5.9 coenzyme F420-reducing hydrogenase FrhD protein compare
MMP_RS03300 +1.5 1.3 TOBE domain-containing protein compare
MMP_RS03215 +1.3 6.9 MBL fold metallo-hydrolase compare
MMP_RS06600 +1.3 2.4 class III signal peptide-containing protein compare
MMP_RS05970 +1.2 5.9 class II SORL domain-containing protein compare
MMP_RS05640 +1.2 6.1 UTP--glucose-1-phosphate uridylyltransferase GalU compare
MMP_RS03385 +1.1 1.4 cation diffusion facilitator family transporter compare
MMP_RS01100 +1.1 1.8 ABC transporter ATP-binding protein compare
MMP_RS05355 +1.1 1.0 hypothetical protein compare
MMP_RS06575 +1.0 2.2 fluoride efflux transporter CrcB compare
MMP_RS06570 +1.0 4.1 DUF190 domain-containing protein compare
MMP_RS08930 +1.0 1.7 hypothetical protein compare
MMP_RS06395 +1.0 3.8 ThiF family adenylyltransferase compare
MMP_RS07890 +1.0 2.2 OB-fold nucleic acid binding domain-containing protein compare
MMP_RS01055 +1.0 3.4 hypothetical protein compare
MMP_RS07130 +1.0 4.4 coenzyme F420 hydrogenase subunit gamma compare
MMP_RS02470 +0.9 1.7 helix-turn-helix transcriptional regulator compare
MMP_RS02490 +0.9 3.6 hypothetical protein compare
MMP_RS06525 +0.9 1.1 YciI family protein compare
MMP_RS00125 +0.9 1.3 DUF2798 domain-containing protein compare
MMP_RS07820 +0.9 3.8 UPF0104 family protein compare
MMP_RS08090 +0.9 4.0 hypothetical protein compare
MMP_RS05435 +0.9 2.9 5'/3'-nucleotidase SurE compare
MMP_RS09025 +0.8 1.1 hypothetical protein compare
MMP_RS00325 +0.8 1.5 RNA-binding protein compare
MMP_RS07815 +0.8 1.2 DUF2120 domain-containing protein compare
MMP_RS03615 +0.8 6.4 4Fe-4S binding protein compare
MMP_RS00395 +0.8 1.3 MGMT family protein compare
MMP_RS08775 +0.8 3.8 methanogenesis marker 9 domain-containing protein compare
MMP_RS03840 +0.8 3.3 hypothetical protein compare
MMP_RS06670 +0.8 2.7 glucose-6-phosphate isomerase compare
MMP_RS06965 +0.8 3.2 TIGR04014 family B12-binding domain/radical SAM domain-containing protein compare
MMP_RS05525 +0.8 3.5 calcium/sodium antiporter compare
MMP_RS02605 +0.8 0.8 MotA/TolQ/ExbB proton channel family protein compare
MMP_RS07840 +0.8 2.1 ribonuclease III compare
MMP_RS06745 +0.7 2.6 DUF2119 domain-containing protein compare
MMP_RS02390 +0.7 2.7 NifB/NifX family molybdenum-iron cluster-binding protein compare
MMP_RS07120 +0.7 3.4 coenzyme F420 hydrogenase subunit alpha compare
MMP_RS02415 +0.7 1.9 site-specific integrase compare
MMP_RS01775 +0.7 1.3 TIGR00297 family protein compare
MMP_RS08705 +0.7 4.1 sulfopyruvate decarboxylase subunit beta compare
MMP_RS06585 +0.7 1.2 DMT family protein compare
MMP_RS08500 +0.7 2.4 pyridoxal 5'-phosphate synthase glutaminase subunit PdxT compare
MMP_RS06610 +0.7 2.0 DUF2334 domain-containing protein compare
MMP_RS01620 +0.7 2.0 hypothetical protein compare
MMP_RS07620 +0.7 1.8 energy-coupling factor ABC transporter substrate-binding protein compare
MMP_RS02915 +0.7 3.2 amino acid ABC transporter permease compare
MMP_RS03965 +0.7 1.5 hypothetical protein compare
MMP_RS04050 +0.7 2.0 hypothetical protein compare
MMP_RS01460 +0.7 1.9 hypothetical protein compare
MMP_RS00660 +0.7 3.2 alkaline phosphatase family protein compare
MMP_RS08340 +0.6 2.0 4Fe-4S binding protein compare
MMP_RS00635 +0.6 2.5 energy-coupling factor transporter transmembrane protein EcfT compare
MMP_RS07895 +0.6 1.6 cytochrome c compare
MMP_RS02675 +0.6 2.1 hypothetical protein compare
MMP_RS07540 +0.6 1.4 CBS domain-containing protein compare
MMP_RS00880 +0.6 1.8 ribosome assembly RNA-binding protein YhbY compare
MMP_RS06335 +0.6 2.3 HAD family hydrolase compare
MMP_RS02100 +0.6 2.5 metallophosphoesterase compare
MMP_RS01095 +0.6 2.6 iron ABC transporter permease compare
MMP_RS01865 +0.6 0.9 GPR1/FUN34/YaaH family transporter compare
MMP_RS00910 +0.6 2.3 2-phosphosulfolactate phosphatase compare
MMP_RS05110 +0.6 2.5 16S ribosomal RNA methyltransferase A compare
MMP_RS00185 +0.6 3.3 potassium channel protein compare
MMP_RS00520 +0.6 0.7 RNA polymerase Rpb4 family protein compare
MMP_RS03390 +0.6 2.2 malate dehydrogenase compare
MMP_RS07695 +0.6 2.4 DUF3236 domain-containing protein compare
MMP_RS08555 +0.6 1.5 hypothetical protein compare
MMP_RS06500 +0.6 2.9 ATP-binding protein compare
MMP_RS04595 +0.5 2.9 hypothetical protein compare
MMP_RS05535 +0.5 1.4 hypothetical protein compare
MMP_RS00675 +0.5 0.5 nitroreductase family protein compare
MMP_RS03245 +0.5 1.7 DNA repair and recombination protein RadB compare
MMP_RS03440 +0.5 0.7 MoaD/ThiS family protein compare
MMP_RS08620 +0.5 2.3 flagellar accessory protein FlaH compare
MMP_RS07770 +0.5 1.7 alanine racemase compare
MMP_RS07355 +0.5 0.5 transcription factor S compare
MMP_RS00825 +0.5 1.8 fumarylacetoacetate hydrolase family protein compare
MMP_RS05470 +0.5 3.0 DUF523 and DUF1722 domain-containing protein compare
MMP_RS08275 +0.5 2.2 hypothetical protein compare
MMP_RS00335 +0.5 1.6 5-amino-6-(D-ribitylamino)uracil--L-tyrosine 4-hydroxyphenyl transferase CofH compare
MMP_RS04520 +0.5 0.9 nucleoside deaminase compare
MMP_RS05140 +0.5 1.5 helix-turn-helix transcriptional regulator compare
MMP_RS06440 +0.5 2.2 CBS domain-containing protein compare
MMP_RS06765 +0.5 2.5 flap endonuclease-1 compare
MMP_RS03280 +0.5 2.3 pyridoxamine 5'-phosphate oxidase family protein compare
MMP_RS07915 +0.5 1.4 DUF4870 domain-containing protein compare
MMP_RS04145 +0.5 0.8 hypothetical protein compare
MMP_RS07700 +0.5 3.0 DUF1188 domain-containing protein compare
MMP_RS04740 +0.5 2.3 DUF473 domain-containing protein compare
MMP_RS03320 +0.5 1.1 metal-dependent transcriptional regulator compare
MMP_RS03010 +0.5 2.8 cupin domain-containing protein compare
MMP_RS03065 +0.5 1.4 AzlC family ABC transporter permease compare
MMP_RS06910 +0.5 2.2 RlmF-related methyltransferase compare
MMP_RS04850 +0.5 3.6 UPF0254 family protein compare
MMP_RS01895 +0.5 3.9 flippase compare
MMP_RS06550 +0.5 2.3 AMP-binding protein compare
MMP_RS00700 +0.5 1.7 OB-fold nucleic acid binding domain-containing protein compare
MMP_RS08130 +0.5 2.8 IGHMBP2 family helicase compare
MMP_RS01980 +0.5 2.6 trimeric intracellular cation channel family protein compare
MMP_RS02835 +0.5 1.2 CGGC domain-containing protein compare
MMP_RS01060 +0.5 2.4 calcium/sodium antiporter compare
MMP_RS00940 +0.5 2.7 daunorubicin resistance protein DrrA family ABC transporter ATP-binding protein compare
MMP_RS02305 +0.5 2.2 DUF378 domain-containing protein compare
MMP_RS00915 +0.5 1.4 DUF116 domain-containing protein compare
MMP_RS00955 +0.5 2.5 coenzyme gamma-F420-2:alpha-L-glutamate ligase compare
MMP_RS08470 +0.5 2.0 ATP-binding cassette domain-containing protein compare
MMP_RS06535 +0.4 1.8 2-oxoacid:acceptor oxidoreductase family protein compare
MMP_RS01130 +0.4 2.0 flavoprotein compare
MMP_RS00630 +0.4 2.4 ECF transporter S component compare
MMP_RS06900 +0.4 1.0 coenzyme F420-reducing hydrogenase FrhD protein compare
MMP_RS04475 +0.4 1.9 nitrogen fixation compare
MMP_RS00100 +0.4 2.5 tRNA pseudouridine(13) synthase TruD compare
MMP_RS02475 +0.4 0.9 hypothetical protein compare
MMP_RS06905 +0.4 1.0 hypothetical protein compare
MMP_RS06290 +0.4 1.7 DNA repair and recombination protein RadA compare
MMP_RS08440 +0.4 0.9 cell division protein SepF compare
MMP_RS03520 +0.4 0.8 YwbE family protein compare
MMP_RS02645 +0.4 2.2 ArsR family transcriptional regulator compare
MMP_RS08360 +0.4 1.6 hypothetical protein compare
MMP_RS02745 +0.4 1.2 hypothetical protein compare
MMP_RS06520 +0.4 1.4 DUF1786 domain-containing protein compare
MMP_RS08835 +0.4 1.6 H(2)-dependent methylenetetrahydromethanopterin dehydrogenase-related protein compare
MMP_RS00565 +0.4 1.8 CBS domain-containing protein compare
MMP_RS07180 +0.4 2.0 DEAD/DEAH box helicase compare
MMP_RS01805 +0.4 1.1 NUDIX hydrolase compare
MMP_RS00960 +0.4 1.3 iron export ABC transporter permease subunit FetB compare
MMP_RS02965 +0.4 2.1 carboxymuconolactone decarboxylase family protein compare
MMP_RS08890 +0.4 3.2 glycosyltransferase family 4 protein compare
MMP_RS02440 +0.4 1.7 hypothetical protein compare
MMP_RS01940 +0.4 1.7 MoxR family ATPase compare
MMP_RS00800 +0.4 2.1 Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain compare
MMP_RS02595 +0.4 0.5 putative zinc-binding protein compare
MMP_RS05920 +0.4 0.2 50S ribosomal protein L37e compare
MMP_RS08755 +0.4 2.7 sodium:solute symporter family protein compare
MMP_RS01950 +0.4 2.6 hypothetical protein compare
MMP_RS06055 +0.4 1.2 peroxiredoxin compare
MMP_RS00085 +0.4 2.3 DNA cytosine methyltransferase compare
MMP_RS01640 +0.4 2.0 2-oxoacid:acceptor oxidoreductase subunit alpha compare
MMP_RS03785 +0.4 0.9 cupin domain-containing protein compare
MMP_RS01210 +0.4 2.0 sodium:solute symporter compare
MMP_RS05825 +0.4 1.2 peptidyl-prolyl cis-trans isomerase compare
MMP_RS05720 +0.4 1.6 signal recognition particle subunit SRP19/SEC65 family protein compare
MMP_RS06095 +0.4 1.6 ABC transporter ATP-binding protein compare
MMP_RS06365 +0.4 0.9 hypothetical protein compare
MMP_RS05980 +0.4 1.8 ferritin compare
MMP_RS04675 +0.4 1.9 selenouridine synthase SelU-like subunit compare
MMP_RS04720 +0.4 1.1 DedA family protein compare
MMP_RS07420 +0.4 2.0 metalloregulator ArsR/SmtB family transcription factor compare
MMP_RS06480 +0.4 1.3 ABC transporter substrate-binding protein compare
MMP_RS08260 +0.4 1.6 DUF99 family protein compare
MMP_RS00725 +0.4 1.0 5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdC compare
MMP_RS06435 +0.4 1.4 CBS domain-containing protein compare
MMP_RS07850 +0.4 0.7 prephenate dehydratase compare
MMP_RS06110 +0.4 0.9 ATP-dependent protease LonB compare
MMP_RS04285 +0.4 1.5 Ni/Fe hydrogenase subunit alpha compare
MMP_RS03490 +0.4 0.6 DUF2115 domain-containing protein compare
MMP_RS03765 +0.4 1.4 CopG family ribbon-helix-helix protein compare
MMP_RS08605 +0.4 1.5 flagellar protein E compare
MMP_RS07650 +0.4 2.1 TldD/PmbA family protein compare
MMP_RS03220 +0.4 1.0 RNA 2' 3'-cyclic phosphodiesterase compare
MMP_RS08660 +0.4 1.5 DHH family phosphoesterase compare
MMP_RS04945 +0.4 1.2 hypothetical protein compare
MMP_RS08670 +0.3 1.8 metallophosphoesterase compare
MMP_RS03420 +0.3 0.9 acetolactate synthase small subunit compare
MMP_RS05345 +0.3 1.8 hypothetical protein compare
MMP_RS02870 +0.3 1.3 hypothetical protein compare
MMP_RS08315 +0.3 0.8 S-methyl-5-thioribose-1-phosphate isomerase compare
MMP_RS00990 +0.3 1.5 hypothetical protein compare
MMP_RS05835 +0.3 0.3 secondary thiamine-phosphate synthase enzyme YjbQ compare
MMP_RS08160 +0.3 1.1 EamA family transporter compare
MMP_RS08265 +0.3 1.1 rubrerythrin compare
MMP_RS01880 +0.3 2.1 DegT/DnrJ/EryC1/StrS family aminotransferase compare
MMP_RS01030 +0.3 0.8 MTAP family purine nucleoside phosphorylase compare
MMP_RS04350 +0.3 1.9 2-hydroxyacyl-CoA dehydratase family protein compare
MMP_RS00795 +0.3 1.4 formate dehydrogenase H subunit alpha selenocysteine-containing compare
MMP_RS02265 +0.3 0.8 nitroreductase family protein compare
MMP_RS05635 +0.3 1.8 NAD-dependent epimerase/dehydratase family protein compare
MMP_RS07590 +0.3 1.7 hypothetical protein compare
MMP_RS04580 +0.3 1.7 hypothetical protein compare
MMP_RS01470 +0.3 1.1 ATP-binding cassette domain-containing protein compare
MMP_RS01685 +0.3 0.7 indolepyruvate oxidoreductase subunit beta compare
MMP_RS06080 +0.3 1.8 radical SAM protein compare
MMP_RS01525 +0.3 0.5 nucleoside-diphosphate kinase compare
MMP_RS00450 +0.3 0.4 4Fe-4S binding protein compare
MMP_RS03900 +0.3 1.1 minichromosome maintenance protein MCM compare
MMP_RS06560 +0.3 1.5 hypothetical protein compare
MMP_RS05700 +0.3 1.6 TfuA-related McrA-glycine thioamidation protein compare
MMP_RS08640 +0.3 1.5 TIM barrel protein compare
MMP_RS03655 +0.3 1.5 DUF1894 domain-containing protein compare
MMP_RS07075 +0.3 1.0 phosphomannomutase/phosphoglucomutase compare
MMP_RS01120 +0.3 1.1 permease compare
MMP_RS05360 +0.3 1.2 hypothetical protein compare
MMP_RS06010 +0.3 1.5 heavy metal translocating P-type ATPase compare
MMP_RS07885 +0.3 0.4 tripartite tricarboxylate transporter permease compare
MMP_RS08155 +0.3 1.3 hypothetical protein compare
MMP_RS02005 +0.3 1.2 RNA ligase compare


Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in nutrient t1 experiments

For nutrient t1 L-Proline across organisms