Experiment set8IT014 for Klebsiella michiganensis M5al

Compare to:

D-Glucose 20 mM carbon source

200 most important genes:

  gene name fitness t score description  
BWI76_RS02995 -8.3 -8.1 aspartate carbamoyltransferase compare
BWI76_RS11965 -7.9 -5.4 orotidine-5'-phosphate decarboxylase compare
BWI76_RS00805 -7.6 -4.7 5,10-methylenetetrahydrofolate reductase compare
BWI76_RS04675 -7.4 -8.3 3-isopropylmalate dehydrogenase compare
BWI76_RS23360 -7.1 -4.9 diaminopimelate decarboxylase compare
BWI76_RS09645 -7.1 -2.8 thioredoxin-disulfide reductase compare
BWI76_RS07070 -7.1 -6.9 5-(carboxyamino)imidazole ribonucleotide mutase compare
BWI76_RS05015 -7.0 -4.8 transcriptional regulator compare
BWI76_RS21475 -6.8 -7.2 bifunctional chorismate mutase/prephenate dehydrogenase compare
BWI76_RS04670 -6.7 -12.6 3-isopropylmalate dehydratase large subunit compare
BWI76_RS04470 -6.6 -11.4 carbamoyl phosphate synthase large subunit compare
BWI76_RS26085 -6.5 -4.3 3-dehydroquinate synthase compare
BWI76_RS18930 -6.4 -4.2 histidinol-phosphate transaminase compare
BWI76_RS05840 -6.4 -6.5 glutamate 5-kinase compare
BWI76_RS18920 -6.3 -4.8 ATP phosphoribosyltransferase compare
BWI76_RS20350 -6.2 -7.3 amidophosphoribosyltransferase compare
BWI76_RS21265 -6.0 -14.0 phosphoribosylformylglycinamidine synthase compare
BWI76_RS00990 -6.0 -9.9 ketol-acid reductoisomerase compare
BWI76_RS25115 -5.9 -11.0 argininosuccinate synthase compare
BWI76_RS10990 -5.9 -5.6 dihydroorotase compare
BWI76_RS20895 -5.9 -7.0 phosphoribosylaminoimidazolesuccinocarboxamide synthase compare
BWI76_RS09755 -5.8 -11.2 phosphoserine transaminase compare
BWI76_RS04465 -5.8 -7.9 carbamoyl-phosphate synthase small subunit compare
BWI76_RS18935 -5.7 -7.6 bifunctional imidazole glycerol-phosphate dehydratase/histidinol phosphatase compare
BWI76_RS00850 -5.7 -8.5 acetylglutamate kinase compare
BWI76_RS18940 -5.7 -6.0 imidazole glycerol phosphate synthase subunit HisH compare
BWI76_RS08385 -5.7 -6.2 citrate (Si)-synthase compare
BWI76_RS04255 -5.7 -11.5 threonine synthase compare
BWI76_RS00855 -5.7 -9.5 argininosuccinate lyase compare
BWI76_RS11850 -5.6 -11.0 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase compare
BWI76_RS00980 -5.6 -13.5 PLP-dependent threonine dehydratase compare
BWI76_RS04245 -5.6 -15.0 bifunctional aspartate kinase/homoserine dehydrogenase I compare
BWI76_RS04665 -5.5 -22.4 3-isopropylmalate dehydratase small subunit compare
BWI76_RS27385 -5.5 -9.2 orotate phosphoribosyltransferase compare
BWI76_RS00965 -5.4 -2.1 acetolactate synthase 2 small subunit compare
BWI76_RS04685 -5.4 -15.3 putative leucine operon leader peptide compare
BWI76_RS24400 -5.4 -9.7 outer membrane channel protein TolC compare
BWI76_RS04160 -5.4 -6.7 phosphoserine phosphatase compare
BWI76_RS23920 -5.4 -8.1 D-3-phosphoglycerate dehydrogenase compare
BWI76_RS04250 -5.3 -10.1 homoserine kinase compare
BWI76_RS09910 -5.3 -16.8 dihydroorotate dehydrogenase (quinone) compare
BWI76_RS26570 -5.3 -5.2 anion permease compare
BWI76_RS01615 -5.3 -11.9 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase compare
BWI76_RS11840 -5.3 -6.9 tryptophan synthase subunit alpha compare
BWI76_RS00785 -5.3 -8.0 cystathionine gamma-synthase compare
BWI76_RS01800 -5.3 -7.2 glucose-6-phosphate isomerase compare
BWI76_RS11860 -5.2 -7.3 anthranilate synthase component I compare
BWI76_RS04240 -5.2 -2.2 thr operon leader peptide compare
BWI76_RS07065 -5.1 -6.3 5-(carboxyamino)imidazole ribonucleotide synthase compare
BWI76_RS09760 -5.1 -4.8 3-phosphoshikimate 1-carboxyvinyltransferase compare
BWI76_RS20355 -5.1 -2.5 colicin V production protein compare
BWI76_RS00975 -5.1 -7.8 dihydroxy-acid dehydratase compare
BWI76_RS18955 -5.1 -4.3 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase compare
BWI76_RS03010 -5.1 -6.6 ornithine carbamoyltransferase compare
BWI76_RS11855 -5.0 -7.6 bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase compare
BWI76_RS05835 -5.0 -5.5 gamma-glutamyl-phosphate reductase compare
BWI76_RS01655 -5.0 -6.1 homoserine O-succinyltransferase compare
BWI76_RS11845 -4.9 -3.8 tryptophan synthase subunit beta compare
BWI76_RS05200 -4.8 -3.3 bifunctional uridylyltransferase/uridylyl-removing protein compare
BWI76_RS23365 -4.8 -9.8 LysR family transcriptional regulator compare
BWI76_RS00835 -4.8 -14.5 phosphoenolpyruvate carboxylase compare
BWI76_RS15115 -4.7 -6.5 MFS transporter compare
BWI76_RS04645 -4.7 -6.0 3-dehydroquinase compare
BWI76_RS18950 -4.7 -6.7 imidazole glycerol phosphate synthase cyclase subunit compare
BWI76_RS22765 -4.7 -16.5 sulfite reductase subunit alpha compare
BWI76_RS23220 -4.7 -7.9 amino-acid N-acetyltransferase compare
BWI76_RS00400 -4.6 -3.1 glutamine synthetase compare
BWI76_RS22760 -4.6 -10.0 sulfite reductase subunit beta compare
BWI76_RS18925 -4.5 -5.2 histidinol dehydrogenase compare
BWI76_RS24285 -4.5 -5.9 cystathionine beta-lyase compare
BWI76_RS20965 -4.4 -5.5 phosphoribosylformylglycinamidine cyclo-ligase compare
BWI76_RS01200 -4.4 -4.1 diaminopimelate epimerase compare
BWI76_RS23240 -4.3 -3.0 exonuclease V subunit gamma compare
BWI76_RS04680 -4.3 -12.6 2-isopropylmalate synthase compare
BWI76_RS20435 -4.3 -2.3 chorismate synthase compare
BWI76_RS00180 -4.2 -2.3 F0F1 ATP synthase subunit epsilon compare
BWI76_RS23265 -4.1 -5.0 hypothetical protein compare
BWI76_RS20650 -4.1 -2.8 phosphoenolpyruvate--protein phosphotransferase compare
BWI76_RS02735 -4.1 -7.4 3'(2'),5'-bisphosphate nucleotidase CysQ compare
BWI76_RS00845 -4.1 -10.6 N-acetyl-gamma-glutamyl-phosphate reductase compare
BWI76_RS01610 -4.1 -6.1 phosphoribosylamine--glycine ligase compare
BWI76_RS22755 -3.9 -7.7 phosphoadenosine phosphosulfate reductase compare
BWI76_RS00985 -3.9 -6.0 transcriptional regulator IlvY compare
BWI76_RS09660 -3.8 -2.6 DNA translocase FtsK compare
BWI76_RS13920 -3.8 -8.1 magnesium-translocating P-type ATPase compare
BWI76_RS23230 -3.7 -2.6 exodeoxyribonuclease V subunit beta compare
BWI76_RS25645 -3.5 -7.4 shikimate dehydrogenase compare
BWI76_RS25320 -3.4 -7.8 glutamate synthase compare
BWI76_RS02410 -3.3 -3.2 EF-P beta-lysylation protein EpmB compare
BWI76_RS23480 -3.3 -14.4 EAL domain-containing protein compare
BWI76_RS25315 -3.3 -11.3 glutamate synthase large subunit compare
BWI76_RS17975 -3.2 -5.0 tail-specific protease compare
BWI76_RS04510 -3.2 -3.2 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) compare
BWI76_RS26055 -3.1 -8.4 siroheme synthase compare
BWI76_RS15225 -3.0 -3.2 DeoR family transcriptional regulator compare
BWI76_RS21465 -3.0 -4.0 bifunctional chorismate mutase/prephenate dehydratase compare
BWI76_RS08580 -2.9 -3.4 quinolinate synthetase compare
BWI76_RS20995 -2.8 -9.5 RNA degradosome polyphosphate kinase compare
BWI76_RS06525 -2.8 -5.5 ATP-dependent Clp protease proteolytic subunit compare
BWI76_RS02530 -2.6 -2.9 tRNA dimethylallyltransferase compare
BWI76_RS00345 -2.6 -4.7 protein disulfide oxidoreductase DsbA compare
BWI76_RS06775 -2.5 -12.2 multidrug efflux RND transporter permease subunit compare
BWI76_RS00390 -2.5 -4.8 two-component system sensor histidine kinase NtrB compare
BWI76_RS27390 -2.5 -2.8 ribonuclease PH compare
BWI76_RS09655 -2.4 -5.8 leucine-responsive regulatory protein compare
BWI76_RS26000 -2.4 -7.7 aspartate aminotransferase family protein compare
BWI76_RS16425 -2.4 -3.7 hypothetical protein compare
BWI76_RS23915 -2.4 -2.7 5-formyltetrahydrofolate cyclo-ligase compare
BWI76_RS22690 -2.3 -2.3 adenylyl-sulfate kinase compare
BWI76_RS25065 -2.3 -3.0 polyribonucleotide nucleotidyltransferase compare
BWI76_RS00960 -2.3 -4.5 acetolactate synthase 2 catalytic subunit compare
BWI76_RS01350 -2.2 -1.7 NAD(P)H-flavin reductase compare
BWI76_RS20640 -2.2 -6.1 cysteine synthase A compare
BWI76_RS06530 -2.2 -7.2 ATP-dependent Clp protease ATP-binding subunit ClpX compare
BWI76_RS04530 -2.2 -3.3 peptidylprolyl isomerase SurA compare
BWI76_RS05260 -2.1 -2.3 chaperone compare
BWI76_RS05120 -2.1 -8.2 bifunctional glycosyl transferase/transpeptidase compare
BWI76_RS06780 -2.1 -4.9 MexE family multidrug efflux RND transporter periplasmic adaptor subunit compare
BWI76_RS06765 -2.0 -1.9 transcriptional regulator compare
BWI76_RS26200 -2.0 -8.5 starch synthase compare
BWI76_RS25285 -2.0 -1.9 HPr family phosphocarrier protein compare
BWI76_RS01210 -2.0 -1.8 tyrosine recombinase XerC compare
BWI76_RS27430 -2.0 -1.7 (p)ppGpp synthetase compare
BWI76_RS22805 -1.9 -8.8 GTP diphosphokinase compare
BWI76_RS00385 -1.9 -7.7 nitrogen assimilation regulatory protein compare
BWI76_RS20440 -1.9 -1.7 50S ribosomal protein L3 N(5)-glutamine methyltransferase compare
BWI76_RS15840 -1.8 -2.8 prophage protein compare
BWI76_RS27440 -1.8 -2.9 DNA helicase RecG compare
BWI76_RS13915 -1.8 -3.8 magnesium transport protein MgtC compare
BWI76_RS08525 -1.7 -3.2 colicin transporter compare
BWI76_RS08530 -1.6 -3.6 protein TolA compare
BWI76_RS17720 -1.6 -1.2 muramoyltetrapeptide carboxypeptidase compare
BWI76_RS15110 -1.6 -8.7 putative excinuclease ABC subunit A compare
BWI76_RS18715 -1.6 -6.1 hypothetical protein compare
BWI76_RS25335 -1.6 -3.0 stringent starvation protein A compare
BWI76_RS20380 -1.5 -1.6 tRNA pseudouridine(38-40) synthase TruA compare
BWI76_RS06770 -1.5 -7.9 Hha toxicity attenuator compare
BWI76_RS27310 -1.5 -8.2 glycosyltransferase compare
BWI76_RS04705 -1.5 -6.3 DNA-binding transcriptional regulator FruR compare
BWI76_RS05450 -1.5 -2.2 ribonuclease HI compare
BWI76_RS04845 -1.5 -8.4 nicotinate-nucleotide pyrophosphorylase compare
BWI76_RS17980 -1.5 -2.4 RNA chaperone ProQ compare
BWI76_RS26460 -1.5 -4.3 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE compare
BWI76_RS16955 -1.4 -1.7 hypothetical protein compare
BWI76_RS01275 -1.4 -4.4 LysR family transcriptional regulator compare
BWI76_RS26455 -1.4 -2.8 4-amino-4-deoxy-L-arabinose-phospho-UDP flippase compare
BWI76_RS25425 -1.4 -2.1 arginine repressor compare
BWI76_RS23270 -1.4 -7.5 phosphoenolpyruvate--protein phosphotransferase PtsP compare
BWI76_RS08665 -1.4 -7.3 6-phosphogluconolactonase compare
BWI76_RS13595 -1.4 -3.3 transcriptional regulator compare
BWI76_RS21075 -1.4 -1.7 membrane protein compare
BWI76_RS18710 -1.4 -9.1 GGDEF-domain containing protein compare
BWI76_RS21350 -1.4 -2.0 anti-RNA polymerase sigma factor SigE compare
BWI76_RS09650 -1.3 -4.2 hypothetical protein compare
BWI76_RS01540 -1.3 -2.3 thiamine biosynthesis protein ThiS compare
BWI76_RS02990 -1.3 -4.2 aspartate carbamoyltransferase regulatory subunit compare
BWI76_RS11130 -1.3 -4.9 PTS glucose transporter subunit IIBC compare
BWI76_RS24025 -1.3 -5.8 agmatinase compare
BWI76_RS24900 -1.3 -1.7 DeoR family transcriptional regulator compare
BWI76_RS26395 -1.2 -2.8 cell division protein FtsE compare
BWI76_RS06395 -1.2 -3.0 tRNA 4-thiouridine(8) synthase ThiI compare
BWI76_RS26775 -1.2 -3.0 endo-1,4-D-glucanase compare
BWI76_RS04100 -1.2 -2.8 peptide chain release factor 3 compare
BWI76_RS16965 -1.2 -2.0 murein lipoprotein compare
BWI76_RS19770 -1.2 -2.4 bifunctional murein DD-endopeptidase/murein LD-carboxypeptidase compare
BWI76_RS04955 -1.2 -2.2 hypoxanthine phosphoribosyltransferase compare
BWI76_RS08120 -1.2 -3.3 cobalt transporter compare
BWI76_RS25070 -1.2 -1.7 hypothetical protein compare
BWI76_RS19870 -1.1 -2.8 malate:quinone oxidoreductase compare
BWI76_RS22700 -1.1 -5.9 sulfate adenylyltransferase subunit 2 compare
BWI76_RS12090 -1.1 -1.0 HNH endonuclease compare
BWI76_RS25160 -1.1 -1.9 transcription elongation factor GreA compare
BWI76_RS23885 -1.1 -1.6 2-octaprenylphenol hydroxylase compare
BWI76_RS01580 -1.1 -2.1 hypothetical protein compare
BWI76_RS01330 -1.1 -2.1 twin-arginine translocase subunit TatC compare
BWI76_RS15830 -1.1 -1.9 hypothetical protein compare
BWI76_RS01630 -1.1 -1.4 16S ribosomal RNA compare
BWI76_RS00335 -1.1 -1.5 hypothetical protein compare
BWI76_RS09870 -1.1 -6.6 aromatic amino acid aminotransferase compare
BWI76_RS13755 -1.1 -1.9 hypothetical protein compare
BWI76_RS17400 -1.1 -1.5 transporter compare
BWI76_RS24075 -1.0 -3.4 glutathione synthase compare
BWI76_RS25600 -1.0 -1.0 tRNA-Thr compare
BWI76_RS16195 -1.0 -1.9 hypothetical protein compare
BWI76_RS23485 -1.0 -4.9 hypothetical protein compare
BWI76_RS10835 -1.0 -1.7 hypothetical protein compare
BWI76_RS21480 -1.0 -2.1 phospho-2-dehydro-3-deoxyheptonate aldolase compare
BWI76_RS22695 -1.0 -3.2 sulfate adenylyltransferase compare
BWI76_RS19840 -1.0 -1.2 hypothetical protein compare
BWI76_RS25060 -1.0 -2.9 lipoprotein NlpI compare
BWI76_RS21580 -1.0 -0.8 SsrA-binding protein compare
BWI76_RS04525 -1.0 -2.2 4-hydroxythreonine-4-phosphate dehydrogenase PdxA compare
BWI76_RS01325 -1.0 -1.8 twin-arginine translocase subunit TatB compare
BWI76_RS00355 -1.0 -1.8 DNA polymerase I compare
BWI76_RS00970 -0.9 -2.1 branched chain amino acid aminotransferase compare
BWI76_RS26075 -0.9 -2.1 DNA adenine methylase compare
BWI76_RS16355 -0.9 -1.3 electron transport complex subunit A compare
BWI76_RS19025 -0.9 -6.5 phosphogluconate dehydrogenase (NADP(+)-dependent, decarboxylating) compare
BWI76_RS24100 -0.9 -3.2 YggS family pyridoxal phosphate enzyme compare
BWI76_RS19685 -0.9 -3.7 lysine transporter compare


Specific Phenotypes

None in this experiment

For Klebsiella michiganensis M5al in carbon source experiments

For carbon source D-Glucose across organisms