Experiment set8IT010 for Pseudomonas fluorescens FW300-N2E2

Compare to:

L-Proline nitrogen source

200 most important genes:

  gene name fitness t score description  
Pf6N2E2_3248 -7.1 -4.9 Probable transmembrane protein compare
Pf6N2E2_4353 -6.6 -4.6 Hydrogen peroxide-inducible genes activator compare
Pf6N2E2_3783 -6.1 -4.2 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
Pf6N2E2_71 -6.1 -5.9 Phosphoribosylanthranilate isomerase (EC 5.3.1.24) compare
Pf6N2E2_64 -6.1 -4.2 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) compare
Pf6N2E2_4597 -6.1 -7.2 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_4825 -6.0 -5.9 Anthranilate phosphoribosyltransferase (EC 2.4.2.18) compare
Pf6N2E2_3630 -5.9 -5.8 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_5177 -5.9 -9.0 Ketol-acid reductoisomerase (EC 1.1.1.86) compare
Pf6N2E2_5175 -5.8 -9.7 Acetolactate synthase large subunit (EC 2.2.1.6) compare
Pf6N2E2_5176 -5.7 -5.6 Acetolactate synthase small subunit (EC 2.2.1.6) compare
Pf6N2E2_3253 -5.6 -5.5 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
Pf6N2E2_77 -5.6 -6.6 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) compare
Pf6N2E2_3060 -5.5 -4.2 Outer membrane protein H precursor compare
Pf6N2E2_3782 -5.5 -3.8 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) compare
Pf6N2E2_4826 -5.4 -7.5 Indole-3-glycerol phosphate synthase (EC 4.1.1.48) compare
Pf6N2E2_50 -5.4 -9.0 Biosynthetic Aromatic amino acid aminotransferase alpha (EC 2.6.1.57) @ Aromatic-amino-acid aminotransferase (EC 2.6.1.57) compare
Pf6N2E2_4047 -5.4 -3.7 Tryptophan synthase alpha chain (EC 4.2.1.20) compare
Pf6N2E2_5006 -5.3 -8.1 Muramoyltetrapeptide carboxypeptidase (EC 3.4.17.13) compare
Pf6N2E2_4048 -5.2 -8.0 Tryptophan synthase beta chain (EC 4.2.1.20) compare
Pf6N2E2_3842 -5.1 -6.1 Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) compare
Pf6N2E2_3839 -5.1 -3.5 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
Pf6N2E2_2073 -4.9 -5.9 Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2) compare
Pf6N2E2_4596 -4.9 -11.5 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_66 -4.9 -11.9 3-isopropylmalate dehydrogenase (EC 1.1.1.85) compare
Pf6N2E2_3940 -4.9 -13.0 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_4564 -4.9 -10.8 Dihydroxy-acid dehydratase (EC 4.2.1.9) compare
Pf6N2E2_3666 -4.8 -5.7 InaA protein compare
Pf6N2E2_1186 -4.8 -7.2 Permease of the drug/metabolite transporter (DMT) superfamily compare
Pf6N2E2_3251 -4.7 -10.9 histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) compare
Pf6N2E2_5014 -4.6 -2.1 Apolipoprotein N-acyltransferase (EC 2.3.1.-) / Copper homeostasis protein CutE compare
Pf6N2E2_4759 -4.5 -17.6 Biotin synthase (EC 2.8.1.6) compare
Pf6N2E2_1189 -4.4 -7.7 Thioredoxin reductase (EC 1.8.1.9) compare
Pf6N2E2_3685 -4.3 -14.8 Transcriptional repressor of PutA and PutP / Proline dehydrogenase (EC 1.5.99.8) (Proline oxidase) / Delta-1-pyrroline-5-carboxylate dehydrogenase (EC 1.5.1.12) compare
Pf6N2E2_3252 -4.2 -10.5 Histidinol dehydrogenase (EC 1.1.1.23) compare
Pf6N2E2_2218 -4.2 -4.1 ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92) compare
Pf6N2E2_3826 -4.1 -6.9 Nitrogen regulation protein NR(I) compare
Pf6N2E2_760 -4.1 -15.4 Na+/H+ antiporter NhaB compare
Pf6N2E2_3841 -4.0 -6.7 Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) compare
Pf6N2E2_3938 -4.0 -17.1 Threonine dehydratase biosynthetic (EC 4.3.1.19) compare
Pf6N2E2_1187 -4.0 -11.3 Probable nikkomycin biosynthesis protein, carboxylase compare
Pf6N2E2_3932 -3.9 -4.5 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) compare
Pf6N2E2_3610 -3.9 -5.1 ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) compare
Pf6N2E2_3264 -3.8 -3.9 Uncharacterized protein YrbK clustered with lipopolysaccharide transporters compare
Pf6N2E2_4187 -3.7 -4.4 Lipid A biosynthesis lauroyl acyltransferase (EC 2.3.1.-) compare
Pf6N2E2_4075 -3.7 -4.4 Phosphate ABC transporter, periplasmic phosphate-binding protein PstS (TC 3.A.1.7.1) compare
Pf6N2E2_1190 -3.6 -8.5 Glutamine-dependent 2-keto-4-methylthiobutyrate transaminase compare
Pf6N2E2_2897 -3.5 -12.5 Glucokinase (EC 2.7.1.2) compare
Pf6N2E2_5156 -3.5 -3.4 Two-component sensor CbrB: intrcellular carbon:nitrogen balance compare
Pf6N2E2_1191 -3.4 -11.1 Thiaminase II (EC 3.5.99.2) compare
Pf6N2E2_4072 -3.4 -5.6 Phosphate transport ATP-binding protein PstB (TC 3.A.1.7.1) compare
Pf6N2E2_2885 -3.3 -7.9 Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) compare
Pf6N2E2_2588 -3.3 -5.1 Anti-sigma F factor antagonist (spoIIAA-2); Anti-sigma B factor antagonist RsbV compare
Pf6N2E2_2574 -3.3 -3.1 Flagellar synthesis regulator FleN compare
Pf6N2E2_2074 -3.3 -2.0 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) compare
Pf6N2E2_2465 -3.2 -7.2 Cys regulon transcriptional activator CysB compare
Pf6N2E2_6058 -3.2 -8.0 FIG139976: hypothetical protein compare
Pf6N2E2_4279 -3.2 -14.0 Pyruvate carboxyl transferase subunit B (EC 6.4.1.1) compare
Pf6N2E2_302 -3.2 -7.5 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) compare
Pf6N2E2_4372 -3.0 -6.7 FIG00460773: hypothetical protein compare
Pf6N2E2_3170 -3.0 -7.6 2-isopropylmalate synthase (EC 2.3.3.13) compare
Pf6N2E2_5780 -3.0 -11.7 Periplasmic protease compare
Pf6N2E2_1188 -3.0 -6.6 Alpha-ketoglutarate-dependent taurine dioxygenase (EC 1.14.11.17) compare
Pf6N2E2_5950 -2.9 -6.0 Phosphate:acyl-ACP acyltransferase PlsX compare
Pf6N2E2_2261 -2.9 -7.7 VacJ-like lipoprotein precursor compare
Pf6N2E2_2258 -2.9 -11.7 Transaldolase (EC 2.2.1.2) compare
Pf6N2E2_5219 -2.8 -10.3 FIG140336: TPR domain protein compare
Pf6N2E2_4638 -2.8 -4.2 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) compare
Pf6N2E2_2706 -2.7 -3.6 Allophanate hydrolase 2 subunit 2 (EC 3.5.1.54) compare
Pf6N2E2_3257 -2.7 -4.4 Uncharacterized ABC transporter, auxiliary component YrbC compare
Pf6N2E2_3684 -2.7 -12.7 Proline/sodium symporter PutP (TC 2.A.21.2.1) @ Propionate/sodium symporter conserved
Pf6N2E2_3825 -2.7 -5.3 Nitrogen regulation protein NtrB (EC 2.7.13.3) compare
Pf6N2E2_658 -2.7 -10.7 sensor histidine kinase compare
Pf6N2E2_5845 -2.6 -7.8 Nucleoside ABC transporter, periplasmic nucleoside-binding protein compare
Pf6N2E2_5183 -2.6 -14.8 Paraquat-inducible protein B compare
Pf6N2E2_2217 -2.6 -6.0 ATP-dependent Clp protease ATP-binding subunit ClpX compare
Pf6N2E2_5316 -2.6 -3.0 Periplasmic thiol:disulfide oxidoreductase DsbB, required for DsbA reoxidation compare
Pf6N2E2_5527 -2.6 -2.8 Cold shock protein CspC compare
Pf6N2E2_5181 -2.5 -13.2 Paraquat-inducible protein A compare
Pf6N2E2_5676 -2.5 -4.5 Aspartokinase (EC 2.7.2.4) compare
Pf6N2E2_5579 -2.5 -6.5 Ornithine carbamoyltransferase (EC 2.1.3.3) compare
Pf6N2E2_3300 -2.5 -4.4 Predicted D-glucarate or D-galactorate regulator, GntR family compare
Pf6N2E2_4464 -2.5 -3.3 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases / CDP-6-deoxy-delta-3,4-glucoseen reductase-like compare
Pf6N2E2_2068 -2.4 -10.3 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13) compare
Pf6N2E2_5339 -2.4 -8.5 ubiquinol cytochrome C oxidoreductase, cytochrome C1 subunit compare
Pf6N2E2_63 -2.4 -3.7 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) compare
Pf6N2E2_2186 -2.4 -7.3 Isovaleryl-CoA dehydrogenase (EC 1.3.8.4) compare
Pf6N2E2_3258 -2.4 -5.4 Uncharacterized ABC transporter, periplasmic component YrbD compare
Pf6N2E2_3835 -2.4 -2.8 Carboxyl-terminal protease (EC 3.4.21.102) compare
Pf6N2E2_3534 -2.3 -3.1 Cobalamin biosynthesis protein CobG compare
Pf6N2E2_3261 -2.3 -5.4 hypothetical protein compare
Pf6N2E2_3786 -2.3 -4.1 Twin-arginine translocation protein TatC compare
Pf6N2E2_3072 -2.3 -10.6 [Protein-PII] uridylyltransferase (EC 2.7.7.59) compare
Pf6N2E2_4204 -2.3 -2.2 rRNA small subunit 7-methylguanosine (m7G) methyltransferase GidB compare
Pf6N2E2_5728 -2.3 -3.5 Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) compare
Pf6N2E2_4159 -2.3 -4.9 Cytochrome c4 compare
Pf6N2E2_4276 -2.3 -6.5 Phosphogluconate repressor HexR, RpiR family compare
Pf6N2E2_3667 -2.2 -2.1 Heptose kinase WapQ, eukaryotic type compare
Pf6N2E2_4352 -2.2 -3.2 ATP-dependent DNA helicase RecG (EC 3.6.1.-) compare
Pf6N2E2_3984 -2.1 -10.8 T1SS associated transglutaminase-like cysteine proteinase LapP compare
Pf6N2E2_2274 -2.1 -7.1 Soluble pyridine nucleotide transhydrogenase (EC 1.6.1.1) compare
Pf6N2E2_5846 -2.1 -10.7 Nucleoside ABC transporter, periplasmic nucleoside-binding protein compare
Pf6N2E2_4797 -2.1 -2.9 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase (EC 2.7.6.3) compare
Pf6N2E2_3554 -2.1 -8.9 GCN5-related N-acetyltransferase compare
Pf6N2E2_5337 -2.1 -6.2 Ubiquinol-cytochrome C reductase iron-sulfur subunit (EC 1.10.2.2) compare
Pf6N2E2_2896 -2.0 -4.9 DNA-binding response regulator GltR, controls specific porins for the entry of glucose compare
Pf6N2E2_4611 -2.0 -3.5 Ferric siderophore transport system, periplasmic binding protein TonB compare
Pf6N2E2_3260 -2.0 -5.0 Uncharacterized ABC transporter, ATP-binding protein YrbF compare
Pf6N2E2_3753 -2.0 -14.2 DamX, an inner membrane protein involved in bile resistance compare
Pf6N2E2_2888 -2.0 -9.7 Glucose-selective porin OprB compare
Pf6N2E2_3665 -2.0 -1.5 serine/threonine protein kinase compare
Pf6N2E2_3282 -2.0 -2.5 FIG005080: Possible exported protein compare
Pf6N2E2_75 -2.0 -5.4 Colicin V production protein compare
Pf6N2E2_2707 -1.9 -4.7 Allophanate hydrolase 2 subunit 1 (EC 3.5.1.54) compare
Pf6N2E2_4764 -1.9 -6.7 Dethiobiotin synthetase (EC 6.3.3.3) compare
Pf6N2E2_70 -1.9 -5.0 tRNA pseudouridine synthase A (EC 4.2.1.70) compare
Pf6N2E2_4071 -1.9 -4.0 Phosphate transport system regulatory protein PhoU compare
Pf6N2E2_5182 -1.9 -6.6 Paraquat-inducible protein A compare
Pf6N2E2_4009 -1.9 -8.7 GGDEF domain protein compare
Pf6N2E2_4416 -1.9 -3.4 Tyrosine recombinase XerC compare
Pf6N2E2_3198 -1.8 -2.3 tRNA-guanine transglycosylase (EC 2.4.2.29) compare
Pf6N2E2_3762 -1.8 -6.9 NADP-dependent malic enzyme (EC 1.1.1.40) compare
Pf6N2E2_1652 -1.8 -3.2 Transcriptional regulator, TetR family compare
Pf6N2E2_5257 -1.8 -7.5 Sulfate adenylyltransferase subunit 2 (EC 2.7.7.4) compare
Pf6N2E2_4278 -1.8 -7.7 Pyruvate carboxyl transferase subunit A (EC 6.4.1.1) compare
Pf6N2E2_5739 -1.8 -2.3 Cobalamin biosynthesis protein BluB @ 5,6-dimethylbenzimidazole synthase, flavin destructase family compare
Pf6N2E2_5743 -1.8 -5.6 Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62) compare
Pf6N2E2_613 -1.8 -2.0 lipoprotein, putative compare
Pf6N2E2_4803 -1.8 -1.2 Bis(5'-nucleosyl)-tetraphosphatase, symmetrical (EC 3.6.1.41) compare
Pf6N2E2_3460 -1.7 -1.8 Exodeoxyribonuclease V beta chain (EC 3.1.11.5) compare
Pf6N2E2_863 -1.7 -6.5 Transcriptional regulator, IclR family compare
Pf6N2E2_5738 -1.7 -7.5 Cobyrinic acid A,C-diamide synthase compare
Pf6N2E2_2586 -1.7 -2.4 Hpt domain protein compare
Pf6N2E2_2527 -1.7 -5.6 Oxidoreductase, short chain dehydrogenase/reductase family compare
Pf6N2E2_2892 -1.7 -9.8 Glucose ABC transport system, periplasmic sugar-binding protein compare
Pf6N2E2_3516 -1.7 -3.3 Probable transmembrane protein compare
Pf6N2E2_3537 -1.7 -5.3 Cobalt-precorrin-6x reductase (EC 1.3.1.54) compare
Pf6N2E2_2823 -1.7 -5.0 Multidrug efflux RND membrane fusion protein MexC compare
Pf6N2E2_2065 -1.7 -4.3 Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133) compare
Pf6N2E2_5258 -1.7 -7.8 Sulfate adenylyltransferase subunit 1 (EC 2.7.7.4) / Adenylylsulfate kinase (EC 2.7.1.25) compare
Pf6N2E2_3533 -1.7 -4.0 Cobalt-precorrin-8x methylmutase (EC 5.4.1.2) compare
Pf6N2E2_4174 -1.6 -9.3 Methionine ABC transporter substrate-binding protein compare
Pf6N2E2_4763 -1.6 -8.7 Biotin synthesis protein BioC compare
Pf6N2E2_3531 -1.6 -6.6 Cobalamin biosynthesis protein CbiG / Cobalt-precorrin-3b C17-methyltransferase compare
Pf6N2E2_2895 -1.6 -8.3 Integral membrane sensor signal transduction histidine kinase (EC 2.7.13.3), glucose catabolism cluster compare
Pf6N2E2_5742 -1.6 -7.2 Cobyric acid synthase (EC 6.3.5.10) compare
Pf6N2E2_3074 -1.6 -2.0 FIG00960973: hypothetical protein compare
Pf6N2E2_3323 -1.6 -4.7 hypothetical protein compare
Pf6N2E2_5746 -1.6 -2.8 Cobalamin synthase compare
Pf6N2E2_178 -1.6 -1.8 Phenylalanyl-tRNA synthetase beta chain (EC 6.1.1.20) compare
Pf6N2E2_5740 -1.6 -5.2 Adenosylcobinamide-phosphate synthase (EC 6.3.1.10) compare
Pf6N2E2_4074 -1.6 -6.6 Phosphate transport system permease protein PstC (TC 3.A.1.7.1) compare
Pf6N2E2_2891 -1.6 -9.3 Glucose ABC transport system, inner membrane component 1 compare
Pf6N2E2_3535 -1.6 -5.7 Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-) / Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-) compare
Pf6N2E2_5524 -1.5 -7.9 Outer membrane porin, OprD family compare
Pf6N2E2_2064 -1.5 -3.9 Cobalt-precorrin-3b C17-methyltransferase compare
Pf6N2E2_2825 -1.5 -4.0 RND efflux system, outer membrane lipoprotein CmeC compare
Pf6N2E2_5338 -1.5 -6.6 Ubiquinol--cytochrome c reductase, cytochrome B subunit (EC 1.10.2.2) compare
Pf6N2E2_5745 -1.5 -5.2 Alpha-ribazole-5'-phosphate phosphatase (EC 3.1.3.73) compare
Pf6N2E2_5741 -1.5 -6.1 L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81) compare
Pf6N2E2_170 -1.5 -3.3 lipoprotein, putative compare
Pf6N2E2_2890 -1.5 -6.0 Glucose ABC transport system, inner membrane component 2 compare
Pf6N2E2_1656 -1.5 -3.6 hypothetical protein compare
Pf6N2E2_5593 -1.5 -3.7 Leucyl-tRNA synthetase compare
Pf6N2E2_2311 -1.5 -6.1 Cytochrome c oxidase subunit CcoO (EC 1.9.3.1) compare
Pf6N2E2_4097 -1.5 -8.1 FIG00953365: hypothetical protein compare
Pf6N2E2_4417 -1.5 -4.0 Protein of unknown function DUF484 compare
Pf6N2E2_3532 -1.5 -6.2 Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130) compare
Pf6N2E2_2473 -1.5 -1.6 Major outer membrane lipoprotein I compare
Pf6N2E2_4394 -1.4 -6.6 Putrescine utilization regulator compare
Pf6N2E2_2060 -1.4 -9.5 CobN component of cobalt chelatase involved in B12 biosynthesis compare
Pf6N2E2_2552 -1.4 -3.9 Cytochrome c heme lyase subunit CcmH compare
Pf6N2E2_2062 -1.4 -2.2 FIG00955561: hypothetical protein compare
Pf6N2E2_4762 -1.4 -3.7 Biotin synthesis protein BioH compare
Pf6N2E2_3778 -1.4 -3.8 FIG00954300: hypothetical protein compare
Pf6N2E2_4761 -1.4 -7.7 8-amino-7-oxononanoate synthase (EC 2.3.1.47) compare
Pf6N2E2_3192 -1.4 -3.6 tRNA:Cm32/Um32 methyltransferase compare
Pf6N2E2_3521 -1.4 -7.0 Sensor histidine kinase/response regulator compare
Pf6N2E2_3664 -1.4 -5.7 Carbamoyltransferase in large core OS assembly cluster compare
Pf6N2E2_3349 -1.4 -2.3 Polyribonucleotide nucleotidyltransferase (EC 2.7.7.8) compare
Pf6N2E2_3856 -1.4 -5.5 Lysine-arginine-ornithine-binding periplasmic protein precursor (TC 3.A.1.3.1) compare
Pf6N2E2_5841 -1.4 -1.5 GlcG protein compare
Pf6N2E2_5679 -1.4 -2.9 hypothetical protein compare
Pf6N2E2_2889 -1.4 -8.3 Glucose ABC transporter, ATP-binding subunit (EC 3.6.3.-) compare
Pf6N2E2_6045 -1.4 -1.8 hypothetical protein compare
Pf6N2E2_4453 -1.4 -10.4 Polyphosphate kinase (EC 2.7.4.1) compare
Pf6N2E2_4631 -1.3 -7.0 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62) compare
Pf6N2E2_5300 -1.3 -9.4 Transcriptional regulator, GntR family domain / Aspartate aminotransferase (EC 2.6.1.1) compare
Pf6N2E2_4277 -1.3 -6.6 LysR family transcriptional regulator PA5437 compare
Pf6N2E2_1932 -1.3 -5.1 Transcriptional regulator, IclR family compare
Pf6N2E2_2059 -1.3 -2.7 ChlI component of cobalt chelatase involved in B12 biosynthesis compare
Pf6N2E2_2340 -1.3 -3.5 Transcriptional regulator, GntR family compare
Pf6N2E2_1673 -1.3 -2.5 Transcriptional regulator, TetR family compare
Pf6N2E2_2428 -1.3 -3.5 Thiol-disulfide isomerase and thioredoxins compare
Pf6N2E2_2753 -1.3 -2.7 HtrA protease/chaperone protein compare
Pf6N2E2_3346 -1.3 -5.7 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) compare
Pf6N2E2_4351 -1.3 -7.4 Predicted signal transduction protein compare
Pf6N2E2_2264 -1.3 -3.6 NADPH dependent preQ0 reductase (EC 1.7.1.13) compare
Pf6N2E2_5402 -1.3 -6.3 ABC transporter for D-Alanine, periplasmic substrate-binding component (from data) compare
Pf6N2E2_3515 -1.3 -5.4 Probable transmembrane protein compare


Specific Phenotypes

For 11 genes in this experiment

For nitrogen source L-Proline in Pseudomonas fluorescens FW300-N2E2

For nitrogen source L-Proline across organisms