Experiment set8IT006 for Methanococcus maripaludis S2

Compare to:

Mc formate, casamino free, with 10mM L-Threonine

200 most detrimental genes:

  gene name fitness t score description  
MMP_RS02230 +7.9 41.4 sodium-dependent transporter compare
MMP_RS01370 +4.7 14.1 acetate--CoA ligase family protein compare
MMP_RS05345 +3.6 14.4 hypothetical protein compare
MMP_RS07355 +3.4 3.5 transcription factor S compare
MMP_RS03420 +3.4 3.4 acetolactate synthase small subunit compare
MMP_RS06340 +3.3 17.9 phosphoadenosine phosphosulfate reductase family protein compare
MMP_RS07115 +3.3 9.9 MBL fold metallo-hydrolase compare
MMP_RS07420 +2.7 10.5 metalloregulator ArsR/SmtB family transcription factor compare
MMP_RS01650 +2.6 2.5 sulfurtransferase TusA family protein compare
MMP_RS06600 +2.5 1.3 class III signal peptide-containing protein compare
MMP_RS03390 +2.4 9.1 malate dehydrogenase compare
MMP_RS07415 +2.4 6.7 molybdopterin-guanine dinucleotide biosynthesis protein MobB compare
MMP_RS06725 +2.4 11.5 hypothetical protein compare
MMP_RS05435 +2.2 7.3 5'/3'-nucleotidase SurE compare
MMP_RS01775 +2.1 3.7 TIGR00297 family protein compare
MMP_RS01955 +2.1 3.9 hypothetical protein compare
MMP_RS06395 +2.0 7.2 ThiF family adenylyltransferase compare
MMP_RS04850 +1.9 12.3 UPF0254 family protein compare
MMP_RS08440 +1.8 5.3 cell division protein SepF compare
MMP_RS06575 +1.8 8.3 fluoride efflux transporter CrcB compare
MMP_RS07540 +1.8 5.1 CBS domain-containing protein compare
MMP_RS05640 +1.8 4.5 UTP--glucose-1-phosphate uridylyltransferase GalU compare
MMP_RS08500 +1.8 4.5 pyridoxal 5'-phosphate synthase glutaminase subunit PdxT compare
MMP_RS07390 +1.8 2.5 cell division protein FtsZ compare
MMP_RS05355 +1.8 1.4 hypothetical protein compare
MMP_RS07695 +1.7 7.8 DUF3236 domain-containing protein compare
MMP_RS07075 +1.7 2.2 phosphomannomutase/phosphoglucomutase compare
MMP_RS02875 +1.7 10.0 chorismate pyruvate-lyase family protein compare
MMP_RS02870 +1.7 9.3 hypothetical protein compare
MMP_RS03215 +1.6 6.8 MBL fold metallo-hydrolase compare
MMP_RS05250 +1.6 2.8 NFYB/HAP3 family transcription factor subunit compare
MMP_RS02495 +1.6 2.5 hypothetical protein compare
MMP_RS01895 +1.6 7.2 flippase compare
MMP_RS01960 +1.5 1.0 hypothetical protein compare
MMP_RS06325 +1.5 2.0 hypothetical protein compare
MMP_RS06475 +1.5 5.7 FAD-dependent oxidoreductase compare
MMP_RS00735 +1.5 4.3 5 10-methenyltetrahydromethanopterin hydrogenase compare
MMP_RS03340 +1.5 1.1 ABC transporter ATP-binding protein compare
MMP_RS07410 +1.4 5.8 4-demethylwyosine synthase TYW1 compare
MMP_RS07700 +1.4 6.3 DUF1188 domain-containing protein compare
MMP_RS03440 +1.4 1.7 MoaD/ThiS family protein compare
MMP_RS08155 +1.4 3.8 hypothetical protein compare
MMP_RS02675 +1.3 2.1 hypothetical protein compare
MMP_RS06570 +1.3 3.4 DUF190 domain-containing protein compare
MMP_RS01900 +1.3 6.8 hypothetical protein compare
MMP_RS01880 +1.3 4.3 DegT/DnrJ/EryC1/StrS family aminotransferase compare
MMP_RS06310 +1.2 3.5 NAD(P)/FAD-dependent oxidoreductase compare
MMP_RS08930 +1.2 1.6 hypothetical protein compare
MMP_RS00660 +1.2 5.1 alkaline phosphatase family protein compare
MMP_RS01910 +1.2 5.5 UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing) compare
MMP_RS04265 +1.2 2.2 coenzyme F420-reducing hydrogenase FrhD protein compare
MMP_RS07835 +1.2 2.9 TldD/PmbA family protein compare
MMP_RS01875 +1.2 4.8 N-acetyltransferase compare
MMP_RS05535 +1.2 2.3 hypothetical protein compare
MMP_RS01950 +1.2 4.8 hypothetical protein compare
MMP_RS03150 +1.2 4.7 phosphoglycerate mutase compare
MMP_RS08595 +1.2 1.3 flagellar protein C compare
MMP_RS00770 +1.2 2.4 hypothetical protein compare
MMP_RS01905 +1.2 6.5 glycosyltransferase compare
MMP_RS02490 +1.2 1.0 hypothetical protein compare
MMP_RS03385 +1.1 1.2 cation diffusion facilitator family transporter compare
MMP_RS07875 +1.1 3.6 hypothetical protein compare
MMP_RS01475 +1.1 4.2 phosphosulfolactate synthase compare
MMP_RS00725 +1.1 2.6 5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdC compare
MMP_RS04695 +1.1 4.0 selenide water dikinase SelD compare
MMP_RS00315 +1.1 2.6 Nif3-like dinuclear metal center hexameric protein compare
MMP_RS01945 +1.1 4.1 DUF4350 domain-containing protein compare
MMP_RS02010 +1.1 4.4 PHP domain-containing protein compare
MMP_RS03110 +1.1 2.9 glycosyltransferase family 2 protein compare
MMP_RS04785 +1.1 5.8 hypothetical protein compare
MMP_RS08310 +1.1 1.9 TMEM165/GDT1 family protein compare
MMP_RS07125 +1.1 2.5 coenzyme F420-reducing hydrogenase FrhD protein compare
MMP_RS01055 +1.1 3.2 hypothetical protein compare
MMP_RS06130 +1.1 2.9 peptidylprolyl isomerase compare
MMP_RS08300 +1.0 0.8 metal-sulfur cluster assembly factor compare
MMP_RS08070 +1.0 2.0 DUF2096 domain-containing protein compare
MMP_RS02790 +1.0 1.0 class III signal peptide-containing protein compare
MMP_RS07680 +1.0 2.5 DUF366 family protein compare
MMP_RS00125 +1.0 1.3 DUF2798 domain-containing protein compare
MMP_RS06435 +1.0 4.3 CBS domain-containing protein compare
MMP_RS03670 +1.0 2.5 DUF1890 domain-containing protein compare
MMP_RS08600 +1.0 1.6 flagellar protein D compare
MMP_RS00955 +1.0 5.2 coenzyme gamma-F420-2:alpha-L-glutamate ligase compare
MMP_RS01250 +1.0 2.6 tRNA (guanine(26)-N(2))-dimethyltransferase compare
MMP_RS00945 +1.0 1.0 PadR family transcriptional regulator compare
MMP_RS08590 +0.9 2.4 flagellin compare
MMP_RS05975 +0.9 1.1 hypothetical protein compare
MMP_RS00730 +0.9 2.1 5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdB compare
MMP_RS04090 +0.9 2.5 hypothetical protein compare
MMP_RS01540 +0.9 2.3 DUF504 domain-containing protein compare
MMP_RS07890 +0.9 2.0 OB-fold nucleic acid binding domain-containing protein compare
MMP_RS01885 +0.9 3.6 Gfo/Idh/MocA family oxidoreductase compare
MMP_RS08215 +0.9 2.1 DUF483 domain-containing protein compare
MMP_RS06670 +0.9 2.1 glucose-6-phosphate isomerase compare
MMP_RS05845 +0.9 1.2 tRNA-intron lyase compare
MMP_RS04520 +0.9 2.0 nucleoside deaminase compare
MMP_RS08315 +0.9 1.2 S-methyl-5-thioribose-1-phosphate isomerase compare
MMP_RS08890 +0.9 4.7 glycosyltransferase family 4 protein compare
MMP_RS06855 +0.9 4.8 hypothetical protein compare
MMP_RS05140 +0.8 1.4 helix-turn-helix transcriptional regulator compare
MMP_RS08415 +0.8 2.5 radical SAM protein compare
MMP_RS02310 +0.8 1.2 RimK-like ATPgrasp N-terminal domain-containing protein compare
MMP_RS05695 +0.8 2.8 phospholipase D-like domain-containing protein compare
MMP_RS01930 +0.8 4.7 hypothetical protein compare
MMP_RS02290 +0.8 2.9 MBL fold metallo-hydrolase compare
MMP_RS01925 +0.8 3.1 DUF1616 domain-containing protein compare
MMP_RS00825 +0.8 2.0 fumarylacetoacetate hydrolase family protein compare
MMP_RS04730 +0.8 2.6 flavodoxin family protein compare
MMP_RS06860 +0.8 1.3 4Fe-4S binding protein compare
MMP_RS07385 +0.8 1.3 protein translocase SEC61 complex subunit gamma compare
MMP_RS03395 +0.8 2.4 hypothetical protein compare
MMP_RS06320 +0.8 3.3 hypothetical protein compare
MMP_RS01415 +0.8 1.5 DUF2067 domain-containing protein compare
MMP_RS03585 +0.8 2.2 Hsp20/alpha crystallin family protein compare
MMP_RS07650 +0.8 3.9 TldD/PmbA family protein compare
MMP_RS05825 +0.8 1.5 peptidyl-prolyl cis-trans isomerase compare
MMP_RS02145 +0.7 2.6 winged helix-turn-helix transcriptional regulator compare
MMP_RS00705 +0.7 1.6 hypothetical protein compare
MMP_RS08660 +0.7 1.8 DHH family phosphoesterase compare
MMP_RS01160 +0.7 2.5 DMT family transporter compare
MMP_RS03140 +0.7 3.7 hypothetical protein compare
MMP_RS02960 +0.7 3.9 class I SAM-dependent methyltransferase family protein compare
MMP_RS00625 +0.7 2.9 hypothetical protein compare
MMP_RS00185 +0.7 3.5 potassium channel protein compare
MMP_RS00430 +0.7 1.5 hypothetical protein compare
MMP_RS00975 +0.7 3.1 HD domain-containing protein compare
MMP_RS01935 +0.7 3.2 DUF58 domain-containing protein compare
MMP_RS04720 +0.7 1.2 DedA family protein compare
MMP_RS01920 +0.7 4.0 glycosyltransferase family 2 protein compare
MMP_RS04145 +0.7 0.9 hypothetical protein compare
MMP_RS08235 +0.7 2.1 hypothetical protein compare
MMP_RS03320 +0.7 1.2 metal-dependent transcriptional regulator compare
MMP_RS04790 +0.7 3.1 4-hydroxy-tetrahydrodipicolinate reductase compare
MMP_RS06765 +0.7 1.5 flap endonuclease-1 compare
MMP_RS01685 +0.7 1.6 indolepyruvate oxidoreductase subunit beta compare
MMP_RS05850 +0.6 2.0 Ldh family oxidoreductase compare
MMP_RS03400 +0.6 1.0 archease compare
MMP_RS05525 +0.6 2.3 calcium/sodium antiporter compare
MMP_RS00100 +0.6 3.1 tRNA pseudouridine(13) synthase TruD compare
MMP_RS07925 +0.6 1.2 haloacid dehalogenase compare
MMP_RS06335 +0.6 1.5 HAD family hydrolase compare
MMP_RS06000 +0.6 1.9 divalent-cation tolerance protein CutA compare
MMP_RS08665 +0.6 3.2 hypothetical protein compare
MMP_RS02475 +0.6 0.7 hypothetical protein compare
MMP_RS01975 +0.6 3.5 hypothetical protein compare
MMP_RS02130 +0.6 1.7 zinc metalloprotease HtpX compare
MMP_RS05980 +0.6 2.9 ferritin compare
MMP_RS02890 +0.6 1.9 TIGR00296 family protein compare
MMP_RS01915 +0.6 3.2 DUF354 domain-containing protein compare
MMP_RS04020 +0.6 1.3 hypothetical protein compare
MMP_RS05470 +0.6 3.3 DUF523 and DUF1722 domain-containing protein compare
MMP_RS00795 +0.6 1.9 formate dehydrogenase H subunit alpha selenocysteine-containing compare
MMP_RS04475 +0.6 1.5 nitrogen fixation compare
MMP_RS05175 +0.6 1.9 hypothetical protein compare
MMP_RS04690 +0.6 1.8 class III signal peptide-containing protein compare
MMP_RS02595 +0.6 0.6 putative zinc-binding protein compare
MMP_RS08775 +0.5 2.0 methanogenesis marker 9 domain-containing protein compare
MMP_RS05420 +0.5 1.6 DUF61 family protein compare
MMP_RS00450 +0.5 0.8 4Fe-4S binding protein compare
MMP_RS01990 +0.5 1.8 hypothetical protein compare
MMP_RS01030 +0.5 1.2 MTAP family purine nucleoside phosphorylase compare
MMP_RS08630 +0.5 1.6 archaellar assembly protein FlaJ compare
MMP_RS05820 +0.5 1.8 RNA-binding transcriptional accessory protein compare
MMP_RS00630 +0.5 1.6 ECF transporter S component compare
MMP_RS03965 +0.5 1.0 hypothetical protein compare
MMP_RS03430 +0.5 2.3 bile acid:sodium symporter family protein compare
MMP_RS03145 +0.5 1.3 fibrillarin-like rRNA/tRNA 2'-O-methyltransferase compare
MMP_RS06585 +0.5 0.7 DMT family protein compare
MMP_RS04275 +0.5 2.1 hydrogenase iron-sulfur subunit compare
MMP_RS05450 +0.5 2.0 CoB--CoM heterodisulfide reductase subunit C compare
MMP_RS07820 +0.5 1.9 UPF0104 family protein compare
MMP_RS06215 +0.5 0.9 30S ribosomal protein S6e compare
MMP_RS05560 +0.5 1.6 deoxyuridine 5'-triphosphate nucleotidohydrolase compare
MMP_RS01860 +0.5 2.3 hypothetical protein compare
MMP_RS01180 +0.5 0.4 XTP/dITP diphosphatase compare
MMP_RS01865 +0.5 0.6 GPR1/FUN34/YaaH family transporter compare
MMP_RS03790 +0.5 1.9 hypothetical protein compare
MMP_RS04120 +0.5 2.2 hypothetical protein compare
MMP_RS05275 +0.5 2.2 AI-2E family transporter compare
MMP_RS01805 +0.5 1.3 NUDIX hydrolase compare
MMP_RS01435 +0.5 1.8 DMT family transporter compare
MMP_RS00150 +0.5 1.3 AAA family ATPase compare
MMP_RS06735 +0.5 1.6 class I SAM-dependent rRNA methyltransferase compare
MMP_RS08705 +0.5 1.8 sulfopyruvate decarboxylase subunit beta compare
MMP_RS06630 +0.5 0.4 UPF0058 family protein compare
MMP_RS08915 +0.5 1.1 2 5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase compare
MMP_RS06490 +0.5 1.4 hypothetical protein compare
MMP_RS02020 +0.5 0.9 gamma-glutamylcyclotransferase compare
MMP_RS04425 +0.5 3.3 APC family permease compare
MMP_RS06445 +0.5 0.8 DUF89 domain-containing protein compare
MMP_RS01450 +0.5 1.9 tRNA pseudouridine(38-40) synthase TruA compare
MMP_RS00115 +0.5 2.3 radical SAM protein compare
MMP_RS00120 +0.5 1.1 LysR family transcriptional regulator compare
MMP_RS02895 +0.5 1.8 DHH family phosphoesterase compare
MMP_RS02930 +0.5 0.8 class I SAM-dependent methyltransferase compare
MMP_RS07840 +0.5 0.9 ribonuclease III compare
MMP_RS04985 +0.5 1.5 DUF2180 family protein compare
MMP_RS05900 +0.5 1.6 tetratricopeptide repeat protein compare
MMP_RS04840 +0.5 1.8 response regulator compare
MMP_RS01095 +0.4 1.3 iron ABC transporter permease compare


Specific Phenotypes

For 3 genes in this experiment

For nutrient t1 L-Threonine in Methanococcus maripaludis S2

For nutrient t1 L-Threonine across organisms