Experiment set8IT004 for Methanococcus maripaludis S2

Compare to:

Mc formate, casamino free, with 10mM L-Threonine

200 most detrimental genes:

  gene name fitness t score description  
MMP_RS02230 +8.2 43.1 sodium-dependent transporter compare
MMP_RS07355 +4.5 4.6 transcription factor S compare
MMP_RS01370 +4.5 12.7 acetate--CoA ligase family protein compare
MMP_RS07115 +3.5 9.1 MBL fold metallo-hydrolase compare
MMP_RS06340 +3.3 14.6 phosphoadenosine phosphosulfate reductase family protein compare
MMP_RS03420 +3.1 2.7 acetolactate synthase small subunit compare
MMP_RS05345 +2.9 13.3 hypothetical protein compare
MMP_RS07420 +2.8 8.7 metalloregulator ArsR/SmtB family transcription factor compare
MMP_RS05435 +2.6 6.5 5'/3'-nucleotidase SurE compare
MMP_RS07415 +2.4 7.9 molybdopterin-guanine dinucleotide biosynthesis protein MobB compare
MMP_RS05355 +2.4 1.9 hypothetical protein compare
MMP_RS06725 +2.2 10.0 hypothetical protein compare
MMP_RS03390 +2.2 7.8 malate dehydrogenase compare
MMP_RS06395 +2.1 6.7 ThiF family adenylyltransferase compare
MMP_RS05250 +2.1 3.1 NFYB/HAP3 family transcription factor subunit compare
MMP_RS08500 +2.1 5.2 pyridoxal 5'-phosphate synthase glutaminase subunit PdxT compare
MMP_RS07540 +2.0 3.3 CBS domain-containing protein compare
MMP_RS01650 +1.9 1.6 sulfurtransferase TusA family protein compare
MMP_RS01960 +1.9 1.6 hypothetical protein compare
MMP_RS00735 +1.9 3.1 5 10-methenyltetrahydromethanopterin hydrogenase compare
MMP_RS01775 +1.9 3.1 TIGR00297 family protein compare
MMP_RS07695 +1.9 6.8 DUF3236 domain-containing protein compare
MMP_RS04850 +1.9 11.7 UPF0254 family protein compare
MMP_RS06860 +1.8 2.1 4Fe-4S binding protein compare
MMP_RS01895 +1.8 8.4 flippase compare
MMP_RS03440 +1.8 2.1 MoaD/ThiS family protein compare
MMP_RS06600 +1.8 1.8 class III signal peptide-containing protein compare
MMP_RS07410 +1.7 7.1 4-demethylwyosine synthase TYW1 compare
MMP_RS04720 +1.7 2.5 DedA family protein compare
MMP_RS02470 +1.7 0.8 helix-turn-helix transcriptional regulator compare
MMP_RS01885 +1.6 4.9 Gfo/Idh/MocA family oxidoreductase compare
MMP_RS01875 +1.6 5.9 N-acetyltransferase compare
MMP_RS06570 +1.6 4.1 DUF190 domain-containing protein compare
MMP_RS06475 +1.6 5.1 FAD-dependent oxidoreductase compare
MMP_RS06575 +1.6 3.1 fluoride efflux transporter CrcB compare
MMP_RS07875 +1.5 4.0 hypothetical protein compare
MMP_RS07390 +1.5 2.0 cell division protein FtsZ compare
MMP_RS07700 +1.5 6.8 DUF1188 domain-containing protein compare
MMP_RS00725 +1.5 4.6 5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdC compare
MMP_RS08155 +1.5 4.7 hypothetical protein compare
MMP_RS08595 +1.5 1.1 flagellar protein C compare
MMP_RS03215 +1.5 6.3 MBL fold metallo-hydrolase compare
MMP_RS02875 +1.4 7.2 chorismate pyruvate-lyase family protein compare
MMP_RS01880 +1.4 4.1 DegT/DnrJ/EryC1/StrS family aminotransferase compare
MMP_RS01905 +1.4 7.0 glycosyltransferase compare
MMP_RS08775 +1.4 5.6 methanogenesis marker 9 domain-containing protein compare
MMP_RS01900 +1.4 7.4 hypothetical protein compare
MMP_RS06525 +1.3 1.3 YciI family protein compare
MMP_RS07820 +1.3 3.6 UPF0104 family protein compare
MMP_RS00315 +1.3 4.6 Nif3-like dinuclear metal center hexameric protein compare
MMP_RS01955 +1.3 2.8 hypothetical protein compare
MMP_RS00660 +1.3 6.4 alkaline phosphatase family protein compare
MMP_RS02310 +1.2 1.8 RimK-like ATPgrasp N-terminal domain-containing protein compare
MMP_RS02870 +1.2 5.0 hypothetical protein compare
MMP_RS01540 +1.2 3.0 DUF504 domain-containing protein compare
MMP_RS03245 +1.2 2.6 DNA repair and recombination protein RadB compare
MMP_RS08440 +1.2 2.6 cell division protein SepF compare
MMP_RS04090 +1.2 1.4 hypothetical protein compare
MMP_RS02675 +1.1 1.5 hypothetical protein compare
MMP_RS00730 +1.1 2.2 5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdB compare
MMP_RS01525 +1.1 1.8 nucleoside-diphosphate kinase compare
MMP_RS09025 +1.1 1.2 hypothetical protein compare
MMP_RS03110 +1.1 3.4 glycosyltransferase family 2 protein compare
MMP_RS01925 +1.1 4.2 DUF1616 domain-containing protein compare
MMP_RS03150 +1.1 4.8 phosphoglycerate mutase compare
MMP_RS06940 +1.1 2.5 polyprenyl diphosphate synthase compare
MMP_RS02905 +1.0 2.1 2-thiouracil desulfurase family protein compare
MMP_RS07835 +1.0 3.5 TldD/PmbA family protein compare
MMP_RS02145 +1.0 3.4 winged helix-turn-helix transcriptional regulator compare
MMP_RS07680 +1.0 2.2 DUF366 family protein compare
MMP_RS08600 +1.0 2.3 flagellar protein D compare
MMP_RS04520 +1.0 2.6 nucleoside deaminase compare
MMP_RS01475 +1.0 5.3 phosphosulfolactate synthase compare
MMP_RS00655 +1.0 2.2 hypothetical protein compare
MMP_RS04695 +1.0 3.6 selenide water dikinase SelD compare
MMP_RS01910 +1.0 3.7 UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing) compare
MMP_RS06745 +1.0 1.8 DUF2119 domain-containing protein compare
MMP_RS01030 +1.0 2.1 MTAP family purine nucleoside phosphorylase compare
MMP_RS06855 +0.9 5.4 hypothetical protein compare
MMP_RS04785 +0.9 4.7 hypothetical protein compare
MMP_RS07125 +0.9 2.3 coenzyme F420-reducing hydrogenase FrhD protein compare
MMP_RS05850 +0.9 2.7 Ldh family oxidoreductase compare
MMP_RS01420 +0.9 1.6 hypothetical protein compare
MMP_RS02785 +0.9 2.4 MarR family transcriptional regulator compare
MMP_RS01950 +0.9 3.9 hypothetical protein compare
MMP_RS00185 +0.9 4.6 potassium channel protein compare
MMP_RS08070 +0.9 2.1 DUF2096 domain-containing protein compare
MMP_RS07120 +0.9 3.7 coenzyme F420 hydrogenase subunit alpha compare
MMP_RS03100 +0.9 1.4 hypothetical protein compare
MMP_RS03400 +0.9 1.1 archease compare
MMP_RS00955 +0.8 3.9 coenzyme gamma-F420-2:alpha-L-glutamate ligase compare
MMP_RS00770 +0.8 2.8 hypothetical protein compare
MMP_RS06460 +0.8 1.7 pyrimidine dimer DNA glycosylase/endonuclease V compare
MMP_RS00395 +0.8 1.1 MGMT family protein compare
MMP_RS03790 +0.8 3.2 hypothetical protein compare
MMP_RS01865 +0.8 1.1 GPR1/FUN34/YaaH family transporter compare
MMP_RS06435 +0.8 2.2 CBS domain-containing protein compare
MMP_RS00675 +0.8 0.7 nitroreductase family protein compare
MMP_RS01975 +0.8 4.0 hypothetical protein compare
MMP_RS01935 +0.8 3.3 DUF58 domain-containing protein compare
MMP_RS03395 +0.8 2.3 hypothetical protein compare
MMP_RS00140 +0.8 2.1 DUF192 domain-containing protein compare
MMP_RS04685 +0.8 1.2 DUF126 domain-containing protein compare
MMP_RS08685 +0.8 3.4 hypothetical protein compare
MMP_RS05640 +0.8 2.0 UTP--glucose-1-phosphate uridylyltransferase GalU compare
MMP_RS02930 +0.8 1.3 class I SAM-dependent methyltransferase compare
MMP_RS06130 +0.8 2.0 peptidylprolyl isomerase compare
MMP_RS06980 +0.8 2.4 tRNA 2-thiocytidine biosynthesis TtcA family protein compare
MMP_RS05535 +0.8 1.5 hypothetical protein compare
MMP_RS04195 +0.8 0.6 flavodoxin compare
MMP_RS08890 +0.8 3.9 glycosyltransferase family 4 protein compare
MMP_RS01930 +0.8 4.1 hypothetical protein compare
MMP_RS00050 +0.8 3.6 AarF/UbiB family protein compare
MMP_RS01095 +0.8 2.1 iron ABC transporter permease compare
MMP_RS02440 +0.7 2.2 hypothetical protein compare
MMP_RS07095 +0.7 1.7 PspC domain-containing protein compare
MMP_RS08310 +0.7 1.2 TMEM165/GDT1 family protein compare
MMP_RS03140 +0.7 2.9 hypothetical protein compare
MMP_RS06440 +0.7 2.0 CBS domain-containing protein compare
MMP_RS03145 +0.7 3.1 fibrillarin-like rRNA/tRNA 2'-O-methyltransferase compare
MMP_RS07755 +0.7 0.6 DUF555 domain-containing protein compare
MMP_RS04475 +0.7 2.0 nitrogen fixation compare
MMP_RS01970 +0.7 3.2 TIGR04279 domain-containing protein compare
MMP_RS06320 +0.7 2.2 hypothetical protein compare
MMP_RS07890 +0.7 1.2 OB-fold nucleic acid binding domain-containing protein compare
MMP_RS01945 +0.7 2.3 DUF4350 domain-containing protein compare
MMP_RS06155 +0.7 1.5 DUF4186 domain-containing protein compare
MMP_RS03900 +0.7 2.6 minichromosome maintenance protein MCM compare
MMP_RS03890 +0.7 3.1 DUF2540 domain-containing protein compare
MMP_RS03910 +0.7 1.3 hypothetical protein compare
MMP_RS00450 +0.7 0.9 4Fe-4S binding protein compare
MMP_RS01940 +0.6 1.0 MoxR family ATPase compare
MMP_RS08470 +0.6 2.5 ATP-binding cassette domain-containing protein compare
MMP_RS06540 +0.6 1.3 3-methyl-2-oxobutanoate dehydrogenase subunit VorB compare
MMP_RS01915 +0.6 3.4 DUF354 domain-containing protein compare
MMP_RS08555 +0.6 1.8 hypothetical protein compare
MMP_RS05525 +0.6 2.3 calcium/sodium antiporter compare
MMP_RS02595 +0.6 0.7 putative zinc-binding protein compare
MMP_RS03405 +0.6 2.5 RNA 3'-terminal phosphate cyclase compare
MMP_RS01240 +0.6 0.5 7-cyano-7-deazaguanine synthase QueC compare
MMP_RS05955 +0.6 1.0 CoB--CoM heterodisulfide reductase subunit C compare
MMP_RS07150 +0.6 1.8 MTH895/ArsE family thioredoxin-like protein compare
MMP_RS05665 +0.6 2.2 phosphate ABC transporter permease subunit PstC compare
MMP_RS01415 +0.6 1.3 DUF2067 domain-containing protein compare
MMP_RS02085 +0.6 2.7 inosine/xanthosine triphosphatase compare
MMP_RS08660 +0.6 1.2 DHH family phosphoesterase compare
MMP_RS07570 +0.6 2.0 nucleotidyltransferase family protein compare
MMP_RS02265 +0.6 1.7 nitroreductase family protein compare
MMP_RS08215 +0.6 1.1 DUF483 domain-containing protein compare
MMP_RS08785 +0.6 0.5 RNA-protein complex protein Nop10 compare
MMP_RS02475 +0.6 0.7 hypothetical protein compare
MMP_RS05900 +0.6 1.8 tetratricopeptide repeat protein compare
MMP_RS06015 +0.6 1.4 flavodoxin family protein compare
MMP_RS09050 +0.6 2.0 CAP domain-containing protein compare
MMP_RS06325 +0.6 0.6 hypothetical protein compare
MMP_RS06445 +0.6 1.4 DUF89 domain-containing protein compare
MMP_RS07955 +0.6 1.6 FumA C-terminus/TtdB family hydratase beta subunit compare
MMP_RS07650 +0.6 2.2 TldD/PmbA family protein compare
MMP_RS00145 +0.5 1.8 ATP-dependent Clp protease proteolytic subunit compare
MMP_RS01620 +0.5 1.4 hypothetical protein compare
MMP_RS03430 +0.5 2.4 bile acid:sodium symporter family protein compare
MMP_RS03670 +0.5 1.6 DUF1890 domain-containing protein compare
MMP_RS01685 +0.5 1.1 indolepyruvate oxidoreductase subunit beta compare
MMP_RS02290 +0.5 1.3 MBL fold metallo-hydrolase compare
MMP_RS07155 +0.5 2.0 MFS transporter compare
MMP_RS00825 +0.5 1.8 fumarylacetoacetate hydrolase family protein compare
MMP_RS00850 +0.5 1.1 TIGR01177 family methyltransferase compare
MMP_RS08090 +0.5 1.3 hypothetical protein compare
MMP_RS08940 +0.5 0.4 MetS family NSS transporter small subunit compare
MMP_RS03750 +0.5 1.0 ACT domain-containing protein compare
MMP_RS05800 +0.5 1.6 B12-binding domain-containing radical SAM protein compare
MMP_RS00865 +0.5 1.4 SLC13 family permease compare
MMP_RS00625 +0.5 1.9 hypothetical protein compare
MMP_RS01460 +0.5 1.0 hypothetical protein compare
MMP_RS07075 +0.5 1.3 phosphomannomutase/phosphoglucomutase compare
MMP_RS05990 +0.5 1.2 DsrE family protein compare
MMP_RS05790 +0.5 0.9 HDIG domain-containing protein compare
MMP_RS00100 +0.5 2.7 tRNA pseudouridine(13) synthase TruD compare
MMP_RS01570 +0.5 0.6 hypothetical protein compare
MMP_RS07350 +0.5 0.6 preprotein translocase subunit Sec61beta compare
MMP_RS00975 +0.5 2.0 HD domain-containing protein compare
MMP_RS05820 +0.5 1.3 RNA-binding transcriptional accessory protein compare
MMP_RS09035 +0.5 0.8 hypothetical protein compare
MMP_RS09065 +0.5 2.5 hypothetical protein compare
MMP_RS05580 +0.5 2.7 glycosyltransferase compare
MMP_RS06465 +0.5 2.1 NERD domain-containing protein compare
MMP_RS02190 +0.5 0.9 sulfopyruvate decarboxylase subunit alpha compare
MMP_RS04275 +0.5 1.4 hydrogenase iron-sulfur subunit compare
MMP_RS06225 +0.5 1.2 DNA double-strand break repair nuclease NurA compare
MMP_RS04825 +0.5 2.1 protein-glutamate O-methyltransferase CheR compare
MMP_RS04270 +0.5 1.8 coenzyme F420 hydrogenase subunit alpha compare
MMP_RS06310 +0.5 1.0 NAD(P)/FAD-dependent oxidoreductase compare
MMP_RS01180 +0.5 0.7 XTP/dITP diphosphatase compare
MMP_RS00940 +0.5 1.8 daunorubicin resistance protein DrrA family ABC transporter ATP-binding protein compare
MMP_RS04435 +0.5 2.6 pyridoxamine 5'-phosphate oxidase family protein compare
MMP_RS02910 +0.5 1.2 ABC transporter substrate-binding protein compare
MMP_RS07855 +0.4 1.5 class I SAM-dependent methyltransferase compare
MMP_RS01065 +0.4 1.8 alpha/beta hydrolase compare
MMP_RS06555 +0.4 1.0 cupin domain-containing protein compare
MMP_RS01785 +0.4 1.3 hypothetical protein compare


Specific Phenotypes

For 4 genes in this experiment

For nutrient t1 L-Threonine in Methanococcus maripaludis S2

For nutrient t1 L-Threonine across organisms