Experiment set8IT003 for Pseudomonas fluorescens FW300-N2E2

Compare to:

L-Lysine nitrogen source

200 most important genes:

  gene name fitness t score description  
Pf6N2E2_3248 -6.7 -4.6 Probable transmembrane protein compare
Pf6N2E2_4597 -6.1 -4.2 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_4826 -5.9 -5.7 Indole-3-glycerol phosphate synthase (EC 4.1.1.48) compare
Pf6N2E2_4825 -5.9 -4.0 Anthranilate phosphoribosyltransferase (EC 2.4.2.18) compare
Pf6N2E2_3783 -5.8 -4.0 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
Pf6N2E2_64 -5.7 -3.9 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) compare
Pf6N2E2_77 -5.6 -3.8 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) compare
Pf6N2E2_3610 -5.5 -5.3 ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) compare
Pf6N2E2_5175 -5.4 -9.0 Acetolactate synthase large subunit (EC 2.2.1.6) compare
Pf6N2E2_4596 -5.2 -7.1 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_71 -5.2 -6.2 Phosphoribosylanthranilate isomerase (EC 5.3.1.24) compare
Pf6N2E2_5006 -5.2 -6.1 Muramoyltetrapeptide carboxypeptidase (EC 3.4.17.13) compare
Pf6N2E2_3782 -5.1 -3.5 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) compare
Pf6N2E2_5177 -5.1 -9.8 Ketol-acid reductoisomerase (EC 1.1.1.86) compare
Pf6N2E2_4279 -5.1 -10.4 Pyruvate carboxyl transferase subunit B (EC 6.4.1.1) compare
Pf6N2E2_5176 -5.0 -7.7 Acetolactate synthase small subunit (EC 2.2.1.6) compare
Pf6N2E2_4077 -5.0 -3.4 cytosolic long-chain acyl-CoA thioester hydrolase family protein compare
Pf6N2E2_3253 -5.0 -5.9 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
Pf6N2E2_3630 -4.9 -6.7 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_3751 -4.9 -11.7 Glutamate synthase [NADPH] small chain (EC 1.4.1.13) compare
Pf6N2E2_2507 -4.9 -6.6 Undecaprenyl-phosphate N-acetylglucosaminyl 1-phosphate transferase (EC 2.7.8.-) compare
Pf6N2E2_5150 -4.7 -4.6 Glucose-6-phosphate isomerase (EC 5.3.1.9) compare
Pf6N2E2_4047 -4.6 -5.5 Tryptophan synthase alpha chain (EC 4.2.1.20) compare
Pf6N2E2_4564 -4.6 -10.7 Dihydroxy-acid dehydratase (EC 4.2.1.9) compare
Pf6N2E2_4278 -4.6 -11.1 Pyruvate carboxyl transferase subunit A (EC 6.4.1.1) compare
Pf6N2E2_4048 -4.5 -8.1 Tryptophan synthase beta chain (EC 4.2.1.20) compare
Pf6N2E2_3842 -4.5 -5.3 Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) compare
Pf6N2E2_3752 -4.4 -19.4 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) compare
Pf6N2E2_3839 -4.4 -4.2 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
Pf6N2E2_3252 -4.4 -8.8 Histidinol dehydrogenase (EC 1.1.1.23) compare
Pf6N2E2_3938 -4.4 -15.1 Threonine dehydratase biosynthetic (EC 4.3.1.19) compare
Pf6N2E2_5014 -4.4 -2.0 Apolipoprotein N-acyltransferase (EC 2.3.1.-) / Copper homeostasis protein CutE compare
Pf6N2E2_4778 -4.3 -15.7 Lysine 2-monooxygenase (EC 1.13.12.2) (from data) conserved
Pf6N2E2_4762 -4.3 -4.1 Biotin synthesis protein BioH compare
Pf6N2E2_2897 -4.2 -10.5 Glucokinase (EC 2.7.1.2) compare
Pf6N2E2_3940 -4.2 -11.5 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_2863 -4.2 -8.0 Gluconate permease compare
Pf6N2E2_4764 -4.2 -7.0 Dethiobiotin synthetase (EC 6.3.3.3) compare
Pf6N2E2_3826 -4.2 -5.7 Nitrogen regulation protein NR(I) compare
Pf6N2E2_66 -4.1 -11.1 3-isopropylmalate dehydrogenase (EC 1.1.1.85) compare
Pf6N2E2_3841 -4.0 -4.8 Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) compare
Pf6N2E2_302 -4.0 -7.1 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) compare
Pf6N2E2_4777 -3.9 -10.1 5-aminopentanamidase (EC 3.5.1.30) (from data) conserved
Pf6N2E2_2073 -3.9 -7.0 Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2) compare
Pf6N2E2_4759 -3.9 -15.6 Biotin synthase (EC 2.8.1.6) compare
Pf6N2E2_5160 -3.8 -2.5 C4-type zinc finger protein, DksA/TraR family compare
Pf6N2E2_4779 -3.7 -6.4 Transcriptional regulator, AsnC family conserved
Pf6N2E2_2753 -3.6 -2.5 HtrA protease/chaperone protein compare
Pf6N2E2_1424 -3.6 -2.3 transcriptional regulator, TetR family compare
Pf6N2E2_5156 -3.5 -2.4 Two-component sensor CbrB: intrcellular carbon:nitrogen balance compare
Pf6N2E2_4761 -3.4 -10.1 8-amino-7-oxononanoate synthase (EC 2.3.1.47) compare
Pf6N2E2_5723 -3.3 -12.8 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) compare
Pf6N2E2_658 -3.3 -11.0 sensor histidine kinase compare
Pf6N2E2_4763 -3.3 -10.9 Biotin synthesis protein BioC compare
Pf6N2E2_4631 -3.3 -10.8 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62) compare
Pf6N2E2_4372 -3.3 -5.4 FIG00460773: hypothetical protein compare
Pf6N2E2_2510 -3.3 -6.1 Lipid carrier : UDP-N-acetylgalactosaminyltransferase (EC 2.4.1.-) / Alpha-1,3-N-acetylgalactosamine transferase PglA (EC 2.4.1.-); Putative glycosyltransferase compare
Pf6N2E2_3941 -3.2 -3.8 Adenosine (5')-pentaphospho-(5'')-adenosine pyrophosphohydrolase (EC 3.6.1.-) compare
Pf6N2E2_2885 -3.2 -6.4 Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) compare
Pf6N2E2_2258 -3.1 -11.2 Transaldolase (EC 2.2.1.2) compare
Pf6N2E2_3825 -3.0 -5.0 Nitrogen regulation protein NtrB (EC 2.7.13.3) compare
Pf6N2E2_2074 -3.0 -1.9 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) compare
Pf6N2E2_3932 -2.9 -3.7 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) compare
Pf6N2E2_3908 -2.9 -5.2 Glutamate--cysteine ligase (EC 6.3.2.2) compare
Pf6N2E2_5579 -2.9 -8.5 Ornithine carbamoyltransferase (EC 2.1.3.3) compare
Pf6N2E2_4277 -2.9 -8.8 LysR family transcriptional regulator PA5437 compare
Pf6N2E2_2508 -2.8 -4.8 hypothetical protein compare
Pf6N2E2_3661 -2.8 -5.7 hypothetical protein compare
Pf6N2E2_50 -2.8 -7.9 Biosynthetic Aromatic amino acid aminotransferase alpha (EC 2.6.1.57) @ Aromatic-amino-acid aminotransferase (EC 2.6.1.57) compare
Pf6N2E2_2218 -2.7 -5.6 ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92) compare
Pf6N2E2_2465 -2.7 -6.9 Cys regulon transcriptional activator CysB compare
Pf6N2E2_4638 -2.7 -3.2 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) compare
Pf6N2E2_3170 -2.7 -6.7 2-isopropylmalate synthase (EC 2.3.3.13) compare
Pf6N2E2_3346 -2.6 -6.2 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) compare
Pf6N2E2_3663 -2.6 -7.5 Glycosyl transferase compare
Pf6N2E2_5553 -2.6 -6.1 Quinolinate synthetase (EC 2.5.1.72) compare
Pf6N2E2_2217 -2.5 -5.3 ATP-dependent Clp protease ATP-binding subunit ClpX compare
Pf6N2E2_63 -2.5 -4.1 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) compare
Pf6N2E2_5316 -2.5 -2.9 Periplasmic thiol:disulfide oxidoreductase DsbB, required for DsbA reoxidation compare
Pf6N2E2_3611 -2.5 -2.2 HflC protein compare
Pf6N2E2_3072 -2.5 -10.9 [Protein-PII] uridylyltransferase (EC 2.7.7.59) compare
Pf6N2E2_4009 -2.4 -10.4 GGDEF domain protein compare
Pf6N2E2_3869 -2.4 -9.8 Branched-chain amino acid transport protein AzlC compare
Pf6N2E2_3659 -2.3 -4.4 Protein fixF compare
Pf6N2E2_4013 -2.2 -9.9 5-aminovalerate transaminase (EC 2.6.1.48) (from data) conserved
Pf6N2E2_1056 -2.2 -1.3 Quinone oxidoreductase (EC 1.6.5.5) compare
Pf6N2E2_942 -2.2 -2.9 Mll6465 protein compare
Pf6N2E2_2274 -2.2 -6.3 Soluble pyridine nucleotide transhydrogenase (EC 1.6.1.1) compare
Pf6N2E2_2117 -2.2 -12.6 1,4-alpha-glucan (glycogen) branching enzyme, GH-13-type (EC 2.4.1.18) compare
Pf6N2E2_2752 -2.2 -8.7 Exported zinc metalloprotease YfgC precursor compare
Pf6N2E2_2506 -2.2 -12.6 nucleotide sugar epimerase/dehydratase WbpM compare
Pf6N2E2_2864 -2.1 -1.9 Gluconokinase (EC 2.7.1.12) compare
Pf6N2E2_4987 -2.1 -1.7 MaoC-like domain protein compare
Pf6N2E2_2962 -2.1 -2.9 ABC transporter for L-Lysine, ATPase component (from data) compare
Pf6N2E2_4453 -2.1 -12.9 Polyphosphate kinase (EC 2.7.4.1) compare
Pf6N2E2_4517 -2.1 -5.1 Putrescine transport system permease protein PotI (TC 3.A.1.11.2) compare
Pf6N2E2_5153 -2.1 -6.5 3-methyl-2-oxobutanoate hydroxymethyltransferase (EC 2.1.2.11) compare
Pf6N2E2_2959 -2.1 -8.1 ABC transporter for L-Lysine, permease component 1 (from data) conserved
Pf6N2E2_1932 -2.0 -6.1 Transcriptional regulator, IclR family compare
Pf6N2E2_4187 -2.0 -4.3 Lipid A biosynthesis lauroyl acyltransferase (EC 2.3.1.-) compare
Pf6N2E2_5242 -2.0 -2.3 Malate:quinone oxidoreductase (EC 1.1.5.4) compare
Pf6N2E2_2958 -1.9 -8.1 ABC transporter for L-Lysine, periplasmic substrate-binding component (from data) conserved
Pf6N2E2_3251 -1.9 -8.4 histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) compare
Pf6N2E2_1186 -1.9 -6.0 Permease of the drug/metabolite transporter (DMT) superfamily compare
Pf6N2E2_4611 -1.9 -4.3 Ferric siderophore transport system, periplasmic binding protein TonB compare
Pf6N2E2_4516 -1.8 -9.5 Putrescine transport system permease protein PotH (TC 3.A.1.11.2) compare
Pf6N2E2_3984 -1.8 -9.6 T1SS associated transglutaminase-like cysteine proteinase LapP compare
Pf6N2E2_3658 -1.8 -6.7 Lipid A core - O-antigen ligase and related enzymes compare
Pf6N2E2_2588 -1.8 -3.7 Anti-sigma F factor antagonist (spoIIAA-2); Anti-sigma B factor antagonist RsbV compare
Pf6N2E2_2586 -1.7 -2.2 Hpt domain protein compare
Pf6N2E2_3282 -1.7 -1.9 FIG005080: Possible exported protein compare
Pf6N2E2_2706 -1.7 -2.5 Allophanate hydrolase 2 subunit 2 (EC 3.5.1.54) compare
Pf6N2E2_3240 -1.7 -1.8 Methylated-DNA--protein-cysteine methyltransferase (EC 2.1.1.63) compare
Pf6N2E2_6057 -1.6 -2.7 FIG002781: Alpha-L-glutamate ligase family protein compare
Pf6N2E2_3132 -1.6 -3.4 FIG00954548: hypothetical protein compare
Pf6N2E2_4160 -1.6 -1.7 Cytochrome c5 compare
Pf6N2E2_350 -1.6 -2.4 Gfa-like protein compare
Pf6N2E2_4071 -1.6 -3.6 Phosphate transport system regulatory protein PhoU compare
Pf6N2E2_3027 -1.6 -1.4 Baseplate assembly protein V compare
Pf6N2E2_2960 -1.6 -9.5 ABC transporter for L-Lysine, permease component 2 (from data) conserved
Pf6N2E2_5728 -1.6 -4.0 Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) compare
Pf6N2E2_2527 -1.5 -4.5 Oxidoreductase, short chain dehydrogenase/reductase family compare
Pf6N2E2_4072 -1.5 -4.0 Phosphate transport ATP-binding protein PstB (TC 3.A.1.7.1) compare
Pf6N2E2_3255 -1.5 -3.3 YrbA protein compare
Pf6N2E2_2367 -1.5 -2.2 hypothetical protein compare
Pf6N2E2_4059 -1.5 -1.4 DNA-binding protein HU-alpha compare
Pf6N2E2_2605 -1.5 -4.4 3-oxoacyl-[acyl-carrier-protein] synthase, KASIII (EC 2.3.1.180) compare
Pf6N2E2_2317 -1.5 -4.7 Putative analog of CcoH, COG3198 compare
Pf6N2E2_2473 -1.5 -1.4 Major outer membrane lipoprotein I compare
Pf6N2E2_2402 -1.5 -2.5 hypothetical protein compare
Pf6N2E2_4276 -1.5 -3.4 Phosphogluconate repressor HexR, RpiR family compare
Pf6N2E2_178 -1.5 -1.6 Phenylalanyl-tRNA synthetase beta chain (EC 6.1.1.20) compare
Pf6N2E2_613 -1.5 -1.7 lipoprotein, putative compare
Pf6N2E2_614 -1.4 -6.5 3-carboxymuconate cyclase compare
Pf6N2E2_2899 -1.4 -3.9 NAD-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12) compare
Pf6N2E2_5722 -1.4 -3.9 23S rRNA (Uracil-5-) -methyltransferase RumA (EC 2.1.1.-) ## LSU rRNA m(5)U1939 compare
Pf6N2E2_1173 -1.4 -1.9 hypothetical protein compare
Pf6N2E2_5339 -1.4 -5.6 ubiquinol cytochrome C oxidoreductase, cytochrome C1 subunit compare
Pf6N2E2_4513 -1.4 -7.5 Putrescine ABC transporter putrescine-binding protein PotF (TC 3.A.1.11.2) conserved
Pf6N2E2_4614 -1.4 -3.2 twitching motility protein PilH compare
Pf6N2E2_204 -1.3 -1.7 hypothetical protein compare
Pf6N2E2_3868 -1.3 -5.3 Transcriptional regulator, LysR family compare
Pf6N2E2_4515 -1.3 -8.0 Putrescine transport ATP-binding protein PotG (TC 3.A.1.11.2) compare
Pf6N2E2_865 -1.3 -1.3 Fumarylacetoacetate hydrolase family protein compare
Pf6N2E2_4612 -1.3 -4.3 Glutathione synthetase (EC 6.3.2.3) compare
Pf6N2E2_3725 -1.3 -2.5 FIG085779: Lipoprotein compare
Pf6N2E2_3349 -1.3 -2.2 Polyribonucleotide nucleotidyltransferase (EC 2.7.7.8) compare
Pf6N2E2_4773 -1.3 -1.2 Coenzyme PQQ synthesis protein D compare
Pf6N2E2_4075 -1.3 -3.5 Phosphate ABC transporter, periplasmic phosphate-binding protein PstS (TC 3.A.1.7.1) compare
Pf6N2E2_3770 -1.2 -2.0 ATP-dependent hsl protease ATP-binding subunit HslU compare
Pf6N2E2_3698 -1.2 -2.7 Nicotinamidase family protein YcaC compare
Pf6N2E2_1381 -1.2 -5.3 Aldehyde dehydrogenase (EC 1.2.1.3) compare
Pf6N2E2_5442 -1.2 -8.1 Glucose dehydrogenase, PQQ-dependent (EC 1.1.5.2) compare
Pf6N2E2_2124 -1.2 -2.1 Mg(2+) transport ATPase protein C compare
Pf6N2E2_1317 -1.2 -3.7 P-hydroxyphenylacetate hydroxylase C2:oxygenase component compare
Pf6N2E2_1400 -1.2 -7.1 Sensory box histidine kinase/response regulator compare
Pf6N2E2_4498 -1.2 -8.4 Outer membrane porin, OprD family compare
Pf6N2E2_1720 -1.2 -2.4 hypothetical protein compare
Pf6N2E2_5536 -1.2 -1.4 Holliday junction DNA helicase RuvA compare
Pf6N2E2_1673 -1.2 -2.3 Transcriptional regulator, TetR family compare
Pf6N2E2_2285 -1.2 -1.2 FIG00954079: hypothetical protein compare
Pf6N2E2_3786 -1.2 -3.4 Twin-arginine translocation protein TatC compare
Pf6N2E2_3835 -1.1 -2.4 Carboxyl-terminal protease (EC 3.4.21.102) compare
Pf6N2E2_5405 -1.1 -3.6 ABC transporter for D-Alanine, ATPase component (from data) compare
Pf6N2E2_4824 -1.1 -2.4 Anthranilate synthase, amidotransferase component (EC 4.1.3.27) @ Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85) compare
Pf6N2E2_5258 -1.1 -4.0 Sulfate adenylyltransferase subunit 1 (EC 2.7.7.4) / Adenylylsulfate kinase (EC 2.7.1.25) compare
Pf6N2E2_2312 -1.1 -0.9 Cytochrome c oxidase subunit CcoQ (EC 1.9.3.1) compare
Pf6N2E2_5746 -1.1 -2.6 Cobalamin synthase compare
Pf6N2E2_2890 -1.1 -4.3 Glucose ABC transport system, inner membrane component 2 compare
Pf6N2E2_16 -1.1 -1.6 hypothetical protein compare
Pf6N2E2_5705 -1.1 -1.9 Sensor protein PhoQ (EC 2.7.13.3) compare
Pf6N2E2_3534 -1.1 -2.2 Cobalamin biosynthesis protein CobG compare
Pf6N2E2_37 -1.1 -2.6 6-carboxytetrahydropterin synthase (EC 4.1.2.50) @ Queuosine biosynthesis QueD, PTPS-I compare
Pf6N2E2_4351 -1.1 -6.0 Predicted signal transduction protein compare
Pf6N2E2_88 -1.1 -1.4 hypothetical protein compare
Pf6N2E2_5499 -1.1 -1.2 hypothetical protein compare
Pf6N2E2_2320 -1.1 -2.2 Heavy-metal-associated domain (N-terminus) and membrane-bounded cytochrome biogenesis cycZ-like domain, possible membrane copper tolerance protein compare
Pf6N2E2_3738 -1.1 -1.7 General secretion pathway protein L compare
Pf6N2E2_2758 -1.1 -7.7 L-aspartate oxidase (EC 1.4.3.16) compare
Pf6N2E2_2018 -1.1 -2.4 hypothetical protein compare
Pf6N2E2_5527 -1.1 -1.6 Cold shock protein CspC compare
Pf6N2E2_3521 -1.1 -5.7 Sensor histidine kinase/response regulator compare
Pf6N2E2_5257 -1.1 -5.3 Sulfate adenylyltransferase subunit 2 (EC 2.7.7.4) compare
Pf6N2E2_3807 -1.0 -2.5 Histidine utilization repressor compare
Pf6N2E2_4014 -1.0 -4.5 Succinate-semialdehyde dehydrogenase [NAD(P)+] (EC 1.2.1.16) compare
Pf6N2E2_1223 -1.0 -2.4 Amino acid transporters compare
Pf6N2E2_3270 -1.0 -2.4 Hypothetical ATP-binding protein UPF0042, contains P-loop compare
Pf6N2E2_3221 -1.0 -1.7 FIG00352444: hypothetical protein compare
Pf6N2E2_5950 -1.0 -3.0 Phosphate:acyl-ACP acyltransferase PlsX compare
Pf6N2E2_3480 -1.0 -1.5 Transcriptional regulator, ArsR family compare
Pf6N2E2_3667 -1.0 -0.8 Heptose kinase WapQ, eukaryotic type compare
Pf6N2E2_4678 -1.0 -0.8 hypothetical protein compare
Pf6N2E2_5593 -1.0 -3.5 Leucyl-tRNA synthetase compare
Pf6N2E2_4556 -1.0 -1.9 FIG00953078: hypothetical protein compare
Pf6N2E2_5346 -1.0 -2.3 rRNA small subunit methyltransferase I compare
Pf6N2E2_5338 -1.0 -4.5 Ubiquinol--cytochrome c reductase, cytochrome B subunit (EC 1.10.2.2) compare
Pf6N2E2_5843 -1.0 -1.0 hypothetical protein compare
Pf6N2E2_2186 -1.0 -3.2 Isovaleryl-CoA dehydrogenase (EC 1.3.8.4) compare
Pf6N2E2_1187 -1.0 -3.7 Probable nikkomycin biosynthesis protein, carboxylase compare
Pf6N2E2_3171 -1.0 -1.1 hypothetical protein compare


Specific Phenotypes

For 11 genes in this experiment

For nitrogen source L-Lysine in Pseudomonas fluorescens FW300-N2E2

For nitrogen source L-Lysine across organisms