Experiment set8IT003 for Methanococcus maripaludis S2

Compare to:

Mc formate, casamino free, with 10mM L-Histidine

200 most important genes:

  gene name fitness t score description  
MMP_RS03315 -5.4 -2.7 ferrous iron transport protein A compare
MMP_RS06975 -4.9 -3.9 sulfide-dependent adenosine diphosphate thiazole synthase compare
MMP_RS06355 -4.9 -6.4 molybdenum cofactor biosynthesis protein MoaE compare
MMP_RS01175 -4.8 -7.2 triphosphoribosyl-dephospho-CoA synthase compare
MMP_RS06680 -4.1 -18.3 Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain compare
MMP_RS05500 -4.1 -14.8 2-isopropylmalate synthase compare
MMP_RS07345 -4.0 -9.9 glycine synthesis protein GlyXL (from data) compare
MMP_RS05515 -4.0 -10.7 cyclic pyranopterin monophosphate synthase MoaC compare
MMP_RS03450 -4.0 -5.1 glycine synthesis protein GlyXS (from data) compare
MMP_RS06350 -4.0 -11.8 HesA/MoeB/ThiF family protein compare
MMP_RS06685 -3.9 -17.2 formate dehydrogenase H subunit alpha selenocysteine-containing compare
MMP_RS03640 -3.8 -6.1 archaeal proteasome endopeptidase complex subunit beta compare
MMP_RS03015 -3.7 -17.3 GTP 3' 8-cyclase MoaA compare
MMP_RS06730 -3.5 -3.6 phosphopantothenate/pantothenate synthetase compare
MMP_RS07735 -3.5 -1.4 2-ketoisovalerate ferredoxin oxidoreductase subunit alpha compare
MMP_RS07365 -3.4 -18.2 2-phosphoglycerate kinase compare
MMP_RS06345 -3.3 -13.6 formate dehydrogenase accessory sulfurtransferase FdhD compare
MMP_RS06715 -3.3 -19.5 cache domain-containing protein compare
MMP_RS06700 -3.2 -16.8 hypothetical protein compare
MMP_RS05265 -3.2 -4.7 2-isopropylmalate synthase compare
MMP_RS06720 -3.1 -13.9 response regulator transcription factor compare
MMP_RS01500 -3.1 -6.2 CBS domain-containing protein compare
MMP_RS01545 -3.0 -2.4 CBS domain-containing protein compare
MMP_RS07730 -3.0 -3.5 pyruvate synthase subunit beta compare
MMP_RS08720 -2.9 -3.5 4Fe-4S binding protein compare
MMP_RS04900 -2.8 -22.1 hypothetical protein compare
MMP_RS06175 -2.8 -10.6 winged helix-turn-helix transcriptional regulator compare
MMP_RS07845 -2.8 -2.1 LL-diaminopimelate aminotransferase compare
MMP_RS07635 -2.8 -8.9 MogA/MoaB family molybdenum cofactor biosynthesis protein compare
MMP_RS03960 -2.8 -2.5 hypothetical protein compare
MMP_RS08165 -2.7 -4.5 phosphoglycerate dehydrogenase compare
MMP_RS07185 -2.6 -17.1 pyridoxal phosphate-dependent aminotransferase compare
MMP_RS00040 -2.6 -6.1 TIGR03576 family pyridoxal phosphate-dependent enzyme compare
MMP_RS06705 -2.6 -9.0 formate/nitrite transporter family protein compare
MMP_RS07005 -2.5 -1.2 4Fe-4S binding protein compare
MMP_RS07605 -2.3 -6.5 diadenylate cyclase compare
MMP_RS05875 -2.3 -7.1 hydroxyethylthiazole kinase compare
MMP_RS03445 -2.3 -2.0 methanogenesis marker 17 protein compare
MMP_RS01190 -2.2 -13.1 cadmium-translocating P-type ATPase compare
MMP_RS04890 -2.2 -1.5 adenylyltransferase/cytidyltransferase family protein compare
MMP_RS03435 -2.2 -2.3 ketol-acid reductoisomerase compare
MMP_RS02145 -2.2 -11.0 winged helix-turn-helix transcriptional regulator compare
MMP_RS02280 -2.2 -1.8 DUF211 domain-containing protein compare
MMP_RS06105 -2.2 -12.6 hydrogenase maturation peptidase HycI compare
MMP_RS01380 -2.2 -5.2 PHP domain-containing protein compare
MMP_RS07525 -2.1 -8.7 4Fe-4S binding protein compare
MMP_RS08745 -2.1 -9.1 CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase compare
MMP_RS02240 -2.1 -5.5 methanogenesis marker 7 protein compare
MMP_RS03035 -2.1 -4.8 4-hydroxy-tetrahydrodipicolinate synthase compare
MMP_RS08790 -2.1 -4.5 translation initiation factor IF-2 subunit alpha compare
MMP_RS05930 -2.1 -4.4 3-isopropylmalate dehydratase large subunit compare
MMP_RS07445 -2.0 -7.2 helix-turn-helix domain-containing protein compare
MMP_RS06630 -2.0 -1.8 UPF0058 family protein compare
MMP_RS06295 -2.0 -9.5 methanogenesis marker 14 protein compare
MMP_RS00750 -1.9 -3.8 fumarate hydratase compare
MMP_RS05765 -1.9 -8.4 M42 family metallopeptidase compare
MMP_RS03025 -1.9 -6.8 molybdenum cofactor guanylyltransferase compare
MMP_RS04605 -1.8 -6.9 cobalt ECF transporter T component CbiQ compare
MMP_RS04870 -1.8 -7.4 TIGR02253 family HAD-type hydrolase compare
MMP_RS03110 -1.8 -7.9 glycosyltransferase family 2 protein compare
MMP_RS01325 -1.8 -3.3 dihydroneopterin aldolase family protein compare
MMP_RS01610 -1.8 -3.8 hypothetical protein compare
MMP_RS06340 -1.8 -8.9 phosphoadenosine phosphosulfate reductase family protein compare
MMP_RS07380 -1.8 -3.0 transcription elongation factor Spt5 compare
MMP_RS01755 -1.7 -2.7 DUF2097 domain-containing protein compare
MMP_RS08300 -1.7 -1.8 metal-sulfur cluster assembly factor compare
MMP_RS00290 -1.7 -9.0 hypothetical protein compare
MMP_RS02340 -1.7 -2.0 DNA-directed RNA polymerase subunit E'' compare
MMP_RS05430 -1.6 -6.1 TIGR00288 family NYN domain-containing protein compare
MMP_RS08435 -1.6 -2.7 Era-like GTP-binding protein compare
MMP_RS07600 -1.6 -3.9 Ni-sirohydrochlorin a c-diamide synthase compare
MMP_RS02010 -1.6 -8.8 PHP domain-containing protein compare
MMP_RS08460 -1.6 -4.8 proteasome-activating nucleotidase compare
MMP_RS08715 -1.6 -2.1 formylmethanofuran dehydrogenase subunit B compare
MMP_RS07575 -1.6 -5.5 RNA ligase partner protein compare
MMP_RS00455 -1.6 -9.4 orotate phosphoribosyltransferase-like protein compare
MMP_RS08320 -1.6 -6.3 molybdopterin molybdotransferase MoeA compare
MMP_RS08650 -1.5 -4.5 glutamine--fructose-6-phosphate transaminase (isomerizing) compare
MMP_RS01220 -1.5 -6.2 hypothetical protein compare
MMP_RS00685 -1.5 -4.9 2-phospho-L-lactate guanylyltransferase compare
MMP_RS01020 -1.5 -1.8 3 4-dihydroxy-2-butanone-4-phosphate synthase compare
MMP_RS05540 -1.5 -3.9 hypothetical protein compare
MMP_RS00515 -1.5 -1.3 DUF655 domain-containing protein compare
MMP_RS07545 -1.5 -2.2 HTH domain-containing protein compare
MMP_RS01005 -1.5 -2.3 riboflavin synthase compare
MMP_RS00695 -1.5 -1.9 biotin--[acetyl-CoA-carboxylase] ligase compare
MMP_RS01265 -1.4 -1.7 hypothetical protein compare
MMP_RS06400 -1.4 -2.7 4Fe-4S binding protein compare
MMP_RS07710 -1.4 -6.8 cell division protein FtsZ compare
MMP_RS01365 -1.4 -5.6 archaeal proteasome endopeptidase complex subunit alpha compare
MMP_RS00295 -1.4 -2.5 gamma carbonic anhydrase family protein compare
MMP_RS07630 -1.4 -2.4 ATP-binding cassette domain-containing protein compare
MMP_RS01445 -1.4 -6.5 hypothetical protein compare
MMP_RS00130 -1.3 -1.8 nickel-responsive transcriptional regulator NikR compare
MMP_RS04710 -1.3 -2.7 hypothetical protein compare
MMP_RS01745 -1.3 -4.8 AMP phosphorylase compare
MMP_RS01225 -1.3 -4.2 DUF5379 domain-containing protein compare
MMP_RS01795 -1.3 -1.9 methanogenesis marker 6 protein compare
MMP_RS02165 -1.3 -6.8 tRNA-dihydrouridine synthase compare
MMP_RS00720 -1.3 -6.3 metal-dependent hydrolase compare
MMP_RS05845 -1.2 -2.5 tRNA-intron lyase compare
MMP_RS00060 -1.2 -2.0 3-dehydroquinate synthase II compare
MMP_RS01240 -1.2 -1.9 7-cyano-7-deazaguanine synthase QueC compare
MMP_RS05280 -1.2 -6.2 COG1361 S-layer family protein compare
MMP_RS06285 -1.2 -3.4 precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT compare
MMP_RS03600 -1.2 -2.4 triose-phosphate isomerase compare
MMP_RS06925 -1.2 -2.4 ribonuclease VapC4 compare
MMP_RS05285 -1.2 -6.0 MMPL family transporter compare
MMP_RS01925 -1.2 -8.0 DUF1616 domain-containing protein compare
MMP_RS04620 -1.2 -6.9 cobalt transporter CbiM compare
MMP_RS02345 -1.2 -4.0 GTP-dependent dephospho-CoA kinase family protein compare
MMP_RS07200 -1.2 -6.4 [5-(aminomethyl)furan-3-yl]methyl phosphate kinase compare
MMP_RS06215 -1.1 -2.7 30S ribosomal protein S6e compare
MMP_RS03145 -1.1 -5.7 fibrillarin-like rRNA/tRNA 2'-O-methyltransferase compare
MMP_RS06020 -1.1 -4.8 archaeoflavoprotein AfpA compare
MMP_RS08240 -1.1 -7.2 methanogenesis marker 16 metalloprotein compare
MMP_RS08195 -1.1 -6.7 hypothetical protein compare
MMP_RS04615 -1.1 -4.2 PDGLE domain-containing protein compare
MMP_RS01985 -1.1 -3.0 F420-dependent methylenetetrahydromethanopterin dehydrogenase compare
MMP_RS03305 -1.1 -4.6 winged helix-turn-helix domain-containing protein compare
MMP_RS04780 -1.1 -3.3 ribonuclease P compare
MMP_RS01720 -1.1 -1.6 replication factor C large subunit compare
MMP_RS03580 -1.1 -3.8 signal recognition particle-docking protein FtsY compare
MMP_RS03140 -1.1 -7.3 hypothetical protein compare
MMP_RS01800 -1.1 -2.7 TIGR00303 family protein compare
MMP_RS06625 -1.1 -2.6 DNA primase compare
MMP_RS02235 -1.1 -6.2 CBS domain-containing protein compare
MMP_RS01900 -1.1 -8.6 hypothetical protein compare
MMP_RS07705 -1.1 -6.6 transcriptional regulator compare
MMP_RS01955 -1.1 -3.6 hypothetical protein compare
MMP_RS02175 -1.0 -1.1 DUF1611 domain-containing protein compare
MMP_RS02355 -1.0 -2.8 30S ribosomal protein S27ae compare
MMP_RS03485 -1.0 -3.6 TIGR00267 family protein compare
MMP_RS01195 -1.0 -1.6 metalloregulator ArsR/SmtB family transcription factor compare
MMP_RS01905 -1.0 -8.0 glycosyltransferase compare
MMP_RS01890 -1.0 -4.2 nucleotide sugar dehydrogenase compare
MMP_RS07075 -1.0 -3.9 phosphomannomutase/phosphoglucomutase compare
MMP_RS02800 -1.0 -3.4 nucleotidyltransferase domain-containing protein compare
MMP_RS07410 -1.0 -6.6 4-demethylwyosine synthase TYW1 compare
MMP_RS05920 -1.0 -0.7 50S ribosomal protein L37e compare
MMP_RS06270 -1.0 -5.3 TIGR00300 family protein compare
MMP_RS04695 -1.0 -4.6 selenide water dikinase SelD compare
MMP_RS00620 -0.9 -5.0 4Fe-4S binding protein compare
MMP_RS05505 -0.9 -5.8 class IV adenylate cyclase compare
MMP_RS03250 -0.9 -2.0 MJ1244 family protein compare
MMP_RS01830 -0.9 -1.6 tRNA-Val compare
MMP_RS07960 -0.9 -4.9 sugar phosphate isomerase/epimerase compare
MMP_RS05095 -0.9 -4.8 CO dehydrogenase/acetyl-CoA synthase complex subunit epsilon compare
MMP_RS06230 -0.9 -1.5 helix-turn-helix domain-containing protein compare
MMP_RS04955 -0.9 -3.5 DNA topoisomerase I compare
MMP_RS08210 -0.9 -1.3 phosphatidylglycerophosphatase A compare
MMP_RS05850 -0.9 -3.8 Ldh family oxidoreductase compare
MMP_RS07535 -0.9 -4.9 4Fe-4S binding protein compare
MMP_RS01440 -0.9 -4.7 NAAT family transporter compare
MMP_RS07860 -0.8 -1.1 hypothetical protein compare
MMP_RS07090 -0.8 -5.6 tRNA (adenine-N1)-methyltransferase compare
MMP_RS02135 -0.8 -2.5 DUF5612 domain-containing protein compare
MMP_RS03700 -0.8 -4.8 sodium:proton antiporter compare
MMP_RS01915 -0.8 -7.0 DUF354 domain-containing protein compare
MMP_RS05555 -0.8 -0.9 DUF4040 domain-containing protein compare
MMP_RS01700 -0.8 -0.7 dihydroxy-acid dehydratase compare
MMP_RS03555 -0.8 -4.0 transcriptional regulator compare
MMP_RS07350 -0.8 -1.7 preprotein translocase subunit Sec61beta compare
MMP_RS00555 -0.8 -4.9 MFS transporter compare
MMP_RS02930 -0.8 -2.4 class I SAM-dependent methyltransferase compare
MMP_RS04215 -0.8 -3.4 nickel pincer cofactor biosynthesis protein LarB compare
MMP_RS06120 -0.8 -1.9 UPF0147 family protein compare
MMP_RS02885 -0.8 -5.7 molybdopterin biosynthesis protein compare
MMP_RS08635 -0.8 -1.5 UbiA family prenyltransferase compare
MMP_RS05055 -0.8 -5.9 DUF166 domain-containing protein compare
MMP_RS05510 -0.8 -2.7 Rrf2 family transcriptional regulator compare
MMP_RS05925 -0.7 -3.1 small nuclear ribonucleoprotein compare
MMP_RS07580 -0.7 -2.9 DUF356 domain-containing protein compare
MMP_RS01180 -0.7 -1.0 XTP/dITP diphosphatase compare
MMP_RS05085 -0.7 -4.2 AAA family ATPase compare
MMP_RS05250 -0.7 -1.3 NFYB/HAP3 family transcription factor subunit compare
MMP_RS07955 -0.7 -2.8 FumA C-terminus/TtdB family hydratase beta subunit compare
MMP_RS06930 -0.7 -5.1 MBL fold metallo-hydrolase compare
MMP_RS06895 -0.7 -1.3 selenocysteine-specific translation elongation factor compare
MMP_RS04885 -0.7 -4.8 sulfite exporter TauE/SafE family protein compare
MMP_RS05090 -0.7 -3.3 CO dehydrogenase/CO-methylating acetyl-CoA synthase complex subunit beta compare
MMP_RS01575 -0.7 -4.0 aldolase compare
MMP_RS04090 -0.7 -1.5 hypothetical protein compare
MMP_RS05070 -0.7 -3.8 4Fe-4S dicluster domain-containing protein compare
MMP_RS01960 -0.7 -0.8 hypothetical protein compare
MMP_RS02195 -0.7 -2.1 tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase compare
MMP_RS05065 -0.6 -2.1 CooT family nickel-binding protein compare
MMP_RS06865 -0.6 -1.1 HypC/HybG/HupF family hydrogenase formation chaperone compare
MMP_RS02780 -0.6 -4.4 hypothetical protein compare
MMP_RS01970 -0.6 -5.4 TIGR04279 domain-containing protein compare
MMP_RS05075 -0.6 -5.1 acetyl-CoA decarbonylase/synthase complex subunit gamma compare
MMP_RS06310 -0.6 -3.0 NAD(P)/FAD-dependent oxidoreductase compare
MMP_RS01920 -0.6 -5.4 glycosyltransferase family 2 protein compare
MMP_RS01875 -0.6 -4.5 N-acetyltransferase compare
MMP_RS08415 -0.6 -2.4 radical SAM protein compare
MMP_RS05080 -0.6 -4.3 acetyl-CoA decarbonylase/synthase complex subunit delta compare
MMP_RS01600 -0.6 -1.2 50S ribosomal protein L15e compare
MMP_RS06200 -0.6 -3.9 M24 family metallopeptidase compare
MMP_RS00300 -0.6 -0.6 6 7-dimethyl-8-ribityllumazine synthase compare
MMP_RS06170 -0.6 -4.7 ABC transporter ATP-binding protein compare


Specific Phenotypes

For 1 genes in this experiment

For nutrient t1 L-Histidine in Methanococcus maripaludis S2

For nutrient t1 L-Histidine across organisms