Experiment set8IT001 for Pseudomonas fluorescens FW300-N2E2

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L-Arginine nitrogen source

200 most important genes:

  gene name fitness t score description  
Pf6N2E2_4597 -6.1 -4.2 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_4764 -5.8 -4.0 Dethiobiotin synthetase (EC 6.3.3.3) compare
Pf6N2E2_4825 -5.8 -4.0 Anthranilate phosphoribosyltransferase (EC 2.4.2.18) compare
Pf6N2E2_4826 -5.8 -5.6 Indole-3-glycerol phosphate synthase (EC 4.1.1.48) compare
Pf6N2E2_71 -5.8 -4.0 Phosphoribosylanthranilate isomerase (EC 5.3.1.24) compare
Pf6N2E2_3783 -5.8 -4.0 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
Pf6N2E2_3842 -5.8 -4.0 Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) compare
Pf6N2E2_5006 -5.5 -3.8 Muramoyltetrapeptide carboxypeptidase (EC 3.4.17.13) compare
Pf6N2E2_5175 -5.5 -5.4 Acetolactate synthase large subunit (EC 2.2.1.6) compare
Pf6N2E2_3630 -5.5 -5.3 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_64 -5.4 -3.7 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) compare
Pf6N2E2_77 -5.3 -3.6 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) compare
Pf6N2E2_3932 -5.1 -7.2 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) compare
Pf6N2E2_4596 -5.1 -8.5 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_2897 -5.1 -7.7 Glucokinase (EC 2.7.1.2) compare
Pf6N2E2_5176 -5.0 -6.0 Acetolactate synthase small subunit (EC 2.2.1.6) compare
Pf6N2E2_5669 -5.0 -4.8 Succinylarginine dihydrolase (EC 3.5.3.23) compare
Pf6N2E2_4759 -4.9 -12.6 Biotin synthase (EC 2.8.1.6) compare
Pf6N2E2_3253 -4.8 -5.7 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
Pf6N2E2_4762 -4.8 -4.5 Biotin synthesis protein BioH compare
Pf6N2E2_4564 -4.8 -11.1 Dihydroxy-acid dehydratase (EC 4.2.1.9) compare
Pf6N2E2_4047 -4.8 -4.6 Tryptophan synthase alpha chain (EC 4.2.1.20) compare
Pf6N2E2_3839 -4.7 -3.3 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
Pf6N2E2_66 -4.6 -8.9 3-isopropylmalate dehydrogenase (EC 1.1.1.85) compare
Pf6N2E2_50 -4.6 -7.7 Biosynthetic Aromatic amino acid aminotransferase alpha (EC 2.6.1.57) @ Aromatic-amino-acid aminotransferase (EC 2.6.1.57) compare
Pf6N2E2_3610 -4.6 -5.5 ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) compare
Pf6N2E2_4048 -4.5 -8.1 Tryptophan synthase beta chain (EC 4.2.1.20) compare
Pf6N2E2_2863 -4.5 -6.9 Gluconate permease compare
Pf6N2E2_3940 -4.5 -11.2 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_5177 -4.5 -11.6 Ketol-acid reductoisomerase (EC 1.1.1.86) compare
Pf6N2E2_2073 -4.5 -3.1 Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2) compare
Pf6N2E2_5014 -4.4 -2.1 Apolipoprotein N-acyltransferase (EC 2.3.1.-) / Copper homeostasis protein CutE compare
Pf6N2E2_3252 -4.4 -7.9 Histidinol dehydrogenase (EC 1.1.1.23) compare
Pf6N2E2_3782 -4.4 -4.3 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) compare
Pf6N2E2_2507 -4.4 -6.6 Undecaprenyl-phosphate N-acetylglucosaminyl 1-phosphate transferase (EC 2.7.8.-) compare
Pf6N2E2_4761 -4.3 -10.4 8-amino-7-oxononanoate synthase (EC 2.3.1.47) compare
Pf6N2E2_2465 -4.3 -6.5 Cys regulon transcriptional activator CysB compare
Pf6N2E2_3941 -4.3 -2.9 Adenosine (5')-pentaphospho-(5'')-adenosine pyrophosphohydrolase (EC 3.6.1.-) compare
Pf6N2E2_5153 -4.2 -6.9 3-methyl-2-oxobutanoate hydroxymethyltransferase (EC 2.1.2.11) compare
Pf6N2E2_2258 -4.2 -9.7 Transaldolase (EC 2.2.1.2) compare
Pf6N2E2_4631 -4.2 -11.3 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62) compare
Pf6N2E2_3349 -4.0 -2.8 Polyribonucleotide nucleotidyltransferase (EC 2.7.7.8) compare
Pf6N2E2_5553 -4.0 -7.6 Quinolinate synthetase (EC 2.5.1.72) compare
Pf6N2E2_5663 -4.0 -4.7 L-Arginine ABC transporter, ATPase component (from data) compare
Pf6N2E2_2885 -3.9 -4.7 Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) compare
Pf6N2E2_5661 -3.9 -5.2 L-Arginine ABC transporter, permease protein AotQ (from data) conserved
Pf6N2E2_3346 -3.8 -6.5 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) compare
Pf6N2E2_4763 -3.8 -11.4 Biotin synthesis protein BioC compare
Pf6N2E2_3251 -3.8 -10.6 histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) compare
Pf6N2E2_5668 -3.8 -5.7 Succinylglutamic semialdehyde dehydrogenase (EC 1.2.1.71) compare
Pf6N2E2_5665 -3.8 -10.8 Succinylornithine transaminase (EC 2.6.1.81) compare
Pf6N2E2_3841 -3.8 -5.7 Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) compare
Pf6N2E2_5664 -3.7 -6.2 Arginine pathway regulatory protein ArgR, repressor of arg regulon compare
Pf6N2E2_5671 -3.7 -3.6 Succinylglutamate desuccinylase (EC 3.5.1.96) compare
Pf6N2E2_2510 -3.7 -5.0 Lipid carrier : UDP-N-acetylgalactosaminyltransferase (EC 2.4.1.-) / Alpha-1,3-N-acetylgalactosamine transferase PglA (EC 2.4.1.-); Putative glycosyltransferase compare
Pf6N2E2_5257 -3.6 -11.3 Sulfate adenylyltransferase subunit 2 (EC 2.7.7.4) compare
Pf6N2E2_4279 -3.6 -11.8 Pyruvate carboxyl transferase subunit B (EC 6.4.1.1) compare
Pf6N2E2_2753 -3.5 -2.4 HtrA protease/chaperone protein compare
Pf6N2E2_5660 -3.4 -6.1 L-Arginine ABC transporter, periplasmic substrate-binding component (from data) conserved
Pf6N2E2_5156 -3.4 -2.4 Two-component sensor CbrB: intrcellular carbon:nitrogen balance compare
Pf6N2E2_302 -3.4 -6.8 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) compare
Pf6N2E2_3248 -3.4 -5.6 Probable transmembrane protein compare
Pf6N2E2_1400 -3.4 -10.3 Sensory box histidine kinase/response regulator compare
Pf6N2E2_3170 -3.3 -9.2 2-isopropylmalate synthase (EC 2.3.3.13) compare
Pf6N2E2_3908 -3.3 -3.2 Glutamate--cysteine ligase (EC 6.3.2.2) compare
Pf6N2E2_5728 -3.1 -5.1 Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) compare
Pf6N2E2_3661 -2.9 -5.6 hypothetical protein compare
Pf6N2E2_3198 -2.9 -2.0 tRNA-guanine transglycosylase (EC 2.4.2.29) compare
Pf6N2E2_2514 -2.9 -5.1 regulator of length of O-antigen component of lipopolysaccharide chains compare
Pf6N2E2_2473 -2.8 -1.9 Major outer membrane lipoprotein I compare
Pf6N2E2_2074 -2.8 -1.8 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) compare
Pf6N2E2_1932 -2.7 -6.0 Transcriptional regulator, IclR family compare
Pf6N2E2_3460 -2.7 -1.8 Exodeoxyribonuclease V beta chain (EC 3.1.11.5) compare
Pf6N2E2_63 -2.7 -4.5 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) compare
Pf6N2E2_2513 -2.7 -4.1 UDP-glucose dehydrogenase (EC 1.1.1.22) compare
Pf6N2E2_1381 -2.7 -6.9 Aldehyde dehydrogenase (EC 1.2.1.3) compare
Pf6N2E2_2899 -2.6 -5.2 NAD-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12) compare
Pf6N2E2_3659 -2.6 -5.1 Protein fixF compare
Pf6N2E2_2893 -2.6 -7.0 hypothetical protein compare
Pf6N2E2_2752 -2.5 -8.4 Exported zinc metalloprotease YfgC precursor compare
Pf6N2E2_3664 -2.5 -9.6 Carbamoyltransferase in large core OS assembly cluster compare
Pf6N2E2_1402 -2.5 -5.1 hypothetical protein compare
Pf6N2E2_3095 -2.5 -1.6 hypothetical protein compare
Pf6N2E2_2890 -2.5 -8.5 Glucose ABC transport system, inner membrane component 2 compare
Pf6N2E2_2706 -2.5 -3.0 Allophanate hydrolase 2 subunit 2 (EC 3.5.1.54) compare
Pf6N2E2_2506 -2.5 -12.6 nucleotide sugar epimerase/dehydratase WbpM compare
Pf6N2E2_2864 -2.5 -2.2 Gluconokinase (EC 2.7.1.12) compare
Pf6N2E2_5950 -2.4 -4.6 Phosphate:acyl-ACP acyltransferase PlsX compare
Pf6N2E2_4638 -2.4 -3.6 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) compare
Pf6N2E2_5160 -2.4 -2.5 C4-type zinc finger protein, DksA/TraR family compare
Pf6N2E2_2889 -2.4 -8.7 Glucose ABC transporter, ATP-binding subunit (EC 3.6.3.-) compare
Pf6N2E2_5258 -2.4 -6.9 Sulfate adenylyltransferase subunit 1 (EC 2.7.7.4) / Adenylylsulfate kinase (EC 2.7.1.25) compare
Pf6N2E2_4556 -2.3 -4.9 FIG00953078: hypothetical protein compare
Pf6N2E2_5662 -2.3 -8.9 L-Arginine ABC transporter, permease protein AotM (from data) conserved
Pf6N2E2_4153 -2.3 -2.2 Sensory box histidine kinase compare
Pf6N2E2_5676 -2.3 -3.0 Aspartokinase (EC 2.7.2.4) compare
Pf6N2E2_5666 -2.3 -9.3 Arginine N-succinyltransferase, alpha subunit (EC 2.3.1.109) compare
Pf6N2E2_4206 -2.3 -1.4 Chromosome (plasmid) partitioning protein ParB compare
Pf6N2E2_3984 -2.2 -9.7 T1SS associated transglutaminase-like cysteine proteinase LapP compare
Pf6N2E2_4372 -2.2 -5.4 FIG00460773: hypothetical protein compare
Pf6N2E2_2758 -2.2 -12.3 L-aspartate oxidase (EC 1.4.3.16) compare
Pf6N2E2_3663 -2.2 -6.9 Glycosyl transferase compare
Pf6N2E2_4974 -2.2 -7.4 DedA protein compare
Pf6N2E2_2420 -2.2 -3.5 hypothetical protein compare
Pf6N2E2_3752 -2.2 -14.2 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) compare
Pf6N2E2_2508 -2.1 -3.8 hypothetical protein compare
Pf6N2E2_4278 -2.1 -7.9 Pyruvate carboxyl transferase subunit A (EC 6.4.1.1) compare
Pf6N2E2_3658 -2.1 -7.2 Lipid A core - O-antigen ligase and related enzymes compare
Pf6N2E2_4453 -2.0 -13.7 Polyphosphate kinase (EC 2.7.4.1) compare
Pf6N2E2_4025 -2.0 -2.1 hypothetical protein compare
Pf6N2E2_2892 -2.0 -9.6 Glucose ABC transport system, periplasmic sugar-binding protein compare
Pf6N2E2_1401 -2.0 -4.7 FIG00955631: hypothetical protein compare
Pf6N2E2_5667 -1.9 -5.8 Arginine N-succinyltransferase (EC 2.3.1.109) compare
Pf6N2E2_5527 -1.9 -2.3 Cold shock protein CspC compare
Pf6N2E2_4797 -1.9 -1.6 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase (EC 2.7.6.3) compare
Pf6N2E2_3340 -1.9 -10.5 Fructose repressor FruR, LacI family compare
Pf6N2E2_4009 -1.9 -7.8 GGDEF domain protein compare
Pf6N2E2_4509 -1.9 -6.7 Gamma-glutamyl-putrescine synthetase (EC 6.3.1.11) (from data) conserved
Pf6N2E2_5219 -1.9 -8.1 FIG140336: TPR domain protein compare
Pf6N2E2_3885 -1.9 -2.2 3'(2'),5'-bisphosphate nucleotidase (EC 3.1.3.7) compare
Pf6N2E2_5723 -1.8 -9.5 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) compare
Pf6N2E2_1056 -1.8 -1.1 Quinone oxidoreductase (EC 1.6.5.5) compare
Pf6N2E2_1281 -1.8 -3.3 ATPase involved in DNA repair compare
Pf6N2E2_5337 -1.8 -4.8 Ubiquinol-cytochrome C reductase iron-sulfur subunit (EC 1.10.2.2) compare
Pf6N2E2_2318 -1.8 -7.1 Type cbb3 cytochrome oxidase biogenesis protein CcoI; Copper-translocating P-type ATPase (EC 3.6.3.4) compare
Pf6N2E2_3938 -1.8 -9.9 Threonine dehydratase biosynthetic (EC 4.3.1.19) compare
Pf6N2E2_2013 -1.7 -1.4 hypothetical protein compare
Pf6N2E2_70 -1.7 -3.0 tRNA pseudouridine synthase A (EC 4.2.1.70) compare
Pf6N2E2_6090 -1.7 -2.1 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain compare
Pf6N2E2_4277 -1.7 -6.9 LysR family transcriptional regulator PA5437 compare
Pf6N2E2_2509 -1.7 -2.1 UDP-glucose 4-epimerase (EC 5.1.3.2) compare
Pf6N2E2_2895 -1.7 -6.8 Integral membrane sensor signal transduction histidine kinase (EC 2.7.13.3), glucose catabolism cluster compare
Pf6N2E2_2891 -1.7 -9.1 Glucose ABC transport system, inner membrane component 1 compare
Pf6N2E2_2707 -1.7 -3.8 Allophanate hydrolase 2 subunit 1 (EC 3.5.1.54) compare
Pf6N2E2_5328 -1.7 -4.5 FIG00958649: hypothetical protein compare
Pf6N2E2_2124 -1.7 -1.4 Mg(2+) transport ATPase protein C compare
Pf6N2E2_6035 -1.6 -2.5 alpha/beta hydrolase fold compare
Pf6N2E2_4205 -1.6 -3.9 Chromosome (plasmid) partitioning protein ParA compare
Pf6N2E2_1043 -1.6 -3.9 Transcriptional regulator, IclR family compare
Pf6N2E2_4993 -1.6 -1.7 Gamma-glutamyl phosphate reductase (EC 1.2.1.41) compare
Pf6N2E2_5766 -1.6 -1.0 Quaternary ammonium compound-resistance protein SugE compare
Pf6N2E2_4611 -1.6 -3.5 Ferric siderophore transport system, periplasmic binding protein TonB compare
Pf6N2E2_1293 -1.5 -1.7 COG2879, Hypothetical small protein yjiX compare
Pf6N2E2_613 -1.5 -1.5 lipoprotein, putative compare
Pf6N2E2_2962 -1.5 -1.8 ABC transporter for L-Lysine, ATPase component (from data) compare
Pf6N2E2_451 -1.5 -2.0 transcriptional regulator MvaT, P16 subunit, putative compare
Pf6N2E2_6058 -1.5 -4.7 FIG139976: hypothetical protein compare
Pf6N2E2_3477 -1.5 -1.6 2-Oxobutyrate oxidase, putative compare
Pf6N2E2_4165 -1.5 -4.1 Zinc ABC transporter, periplasmic-binding protein ZnuA compare
Pf6N2E2_3611 -1.5 -1.6 HflC protein compare
Pf6N2E2_3876 -1.4 -3.3 Agmatine deiminase (EC 3.5.3.12) compare
Pf6N2E2_2367 -1.4 -1.0 hypothetical protein compare
Pf6N2E2_1347 -1.4 -2.1 Oxidoreductase, short-chain dehydrogenase/reductase family (EC 1.1.1.-) compare
Pf6N2E2_5739 -1.4 -1.8 Cobalamin biosynthesis protein BluB @ 5,6-dimethylbenzimidazole synthase, flavin destructase family compare
Pf6N2E2_5843 -1.4 -1.4 hypothetical protein compare
Pf6N2E2_5339 -1.4 -4.5 ubiquinol cytochrome C oxidoreductase, cytochrome C1 subunit compare
Pf6N2E2_51 -1.4 -4.1 hypothetical protein compare
Pf6N2E2_5237 -1.4 -1.9 Hypoxanthine-guanine phosphoribosyltransferase (EC 2.4.2.8) compare
Pf6N2E2_5972 -1.4 -2.3 hypothetical protein compare
Pf6N2E2_37 -1.4 -2.0 6-carboxytetrahydropterin synthase (EC 4.1.2.50) @ Queuosine biosynthesis QueD, PTPS-I compare
Pf6N2E2_4417 -1.4 -3.8 Protein of unknown function DUF484 compare
Pf6N2E2_338 -1.4 -1.4 Transcriptional regulator, AraC family compare
Pf6N2E2_1223 -1.4 -2.7 Amino acid transporters compare
Pf6N2E2_5338 -1.3 -6.2 Ubiquinol--cytochrome c reductase, cytochrome B subunit (EC 1.10.2.2) compare
Pf6N2E2_4276 -1.3 -3.5 Phosphogluconate repressor HexR, RpiR family compare
Pf6N2E2_3835 -1.3 -3.3 Carboxyl-terminal protease (EC 3.4.21.102) compare
Pf6N2E2_2264 -1.3 -3.2 NADPH dependent preQ0 reductase (EC 1.7.1.13) compare
Pf6N2E2_2281 -1.3 -2.2 Beta N-acetyl-glucosaminidase (EC 3.2.1.52) compare
Pf6N2E2_6140 -1.3 -0.8 Large Subunit Ribosomal RNA; lsuRNA; LSU rRNA compare
Pf6N2E2_614 -1.3 -6.1 3-carboxymuconate cyclase compare
Pf6N2E2_1691 -1.3 -2.3 hypothetical protein compare
Pf6N2E2_3834 -1.3 -4.1 Lipoprotein NlpD compare
Pf6N2E2_3516 -1.3 -2.1 Probable transmembrane protein compare
Pf6N2E2_4160 -1.3 -1.5 Cytochrome c5 compare
Pf6N2E2_2518 -1.3 -1.2 Cyclohexadienyl dehydrogenase (EC 1.3.1.12)(EC 1.3.1.43) / 5-Enolpyruvylshikimate-3-phosphate synthase (EC 2.5.1.19) compare
Pf6N2E2_4416 -1.3 -2.1 Tyrosine recombinase XerC compare
Pf6N2E2_4168 -1.3 -4.9 Zinc ABC transporter, inner membrane permease protein ZnuB compare
Pf6N2E2_2186 -1.3 -3.8 Isovaleryl-CoA dehydrogenase (EC 1.3.8.4) compare
Pf6N2E2_4418 -1.2 -0.8 Diaminopimelate epimerase (EC 5.1.1.7) compare
Pf6N2E2_3613 -1.2 -5.1 GTP-binding protein HflX compare
Pf6N2E2_2708 -1.2 -3.5 Lactam utilization protein LamB compare
Pf6N2E2_2310 -1.2 -6.3 Cytochrome c oxidase subunit CcoN (EC 1.9.3.1) compare
Pf6N2E2_1441 -1.2 -1.2 Uncharacterized oxidoreductase ydgJ (EC 1.-.-.-) compare
Pf6N2E2_1354 -1.2 -2.6 FIG026291: Hypothetical periplasmic protein compare
Pf6N2E2_3870 -1.2 -2.2 hypothetical protein compare
Pf6N2E2_75 -1.2 -3.1 Colicin V production protein compare
Pf6N2E2_2896 -1.2 -2.1 DNA-binding response regulator GltR, controls specific porins for the entry of glucose compare
Pf6N2E2_1169 -1.2 -2.0 TnpR protein compare
Pf6N2E2_2795 -1.2 -2.4 putative exported protein compare
Pf6N2E2_4159 -1.2 -3.2 Cytochrome c4 compare
Pf6N2E2_3480 -1.2 -1.7 Transcriptional regulator, ArsR family compare
Pf6N2E2_5316 -1.2 -1.5 Periplasmic thiol:disulfide oxidoreductase DsbB, required for DsbA reoxidation compare
Pf6N2E2_5508 -1.2 -1.8 Formyltetrahydrofolate deformylase (EC 3.5.1.10) compare
Pf6N2E2_3589 -1.2 -2.3 Lysine decarboxylase family compare
Pf6N2E2_2317 -1.2 -3.7 Putative analog of CcoH, COG3198 compare
Pf6N2E2_5442 -1.2 -7.2 Glucose dehydrogenase, PQQ-dependent (EC 1.1.5.2) compare
Pf6N2E2_5086 -1.2 -1.2 hypothetical protein compare
Pf6N2E2_833 -1.2 -2.3 Probable Co/Zn/Cd efflux system membrane fusion protein compare
Pf6N2E2_3179 -1.2 -2.1 FIG021952: putative membrane protein compare
Pf6N2E2_2756 -1.2 -4.3 RNA polymerase sigma-H factor AlgT compare


Specific Phenotypes

For 6 genes in this experiment

For nitrogen source L-Arginine in Pseudomonas fluorescens FW300-N2E2

For nitrogen source L-Arginine across organisms