Experiment set8IT001 for Methanococcus maripaludis S2

Compare to:

Mc formate, casamino free, with 10mM L-Histidine

200 most important genes:

  gene name fitness t score description  
MMP_RS03315 -5.4 -2.6 ferrous iron transport protein A compare
MMP_RS06355 -4.5 -5.7 molybdenum cofactor biosynthesis protein MoaE compare
MMP_RS01545 -4.5 -2.2 CBS domain-containing protein compare
MMP_RS01175 -4.1 -6.5 triphosphoribosyl-dephospho-CoA synthase compare
MMP_RS05500 -4.0 -16.8 2-isopropylmalate synthase compare
MMP_RS06685 -3.8 -16.8 formate dehydrogenase H subunit alpha selenocysteine-containing compare
MMP_RS06680 -3.8 -21.8 Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain compare
MMP_RS05515 -3.8 -10.9 cyclic pyranopterin monophosphate synthase MoaC compare
MMP_RS03015 -3.7 -14.0 GTP 3' 8-cyclase MoaA compare
MMP_RS07345 -3.6 -8.8 glycine synthesis protein GlyXL (from data) compare
MMP_RS06350 -3.6 -10.8 HesA/MoeB/ThiF family protein compare
MMP_RS06715 -3.5 -20.4 cache domain-containing protein compare
MMP_RS04710 -3.4 -3.6 hypothetical protein compare
MMP_RS06700 -3.3 -17.7 hypothetical protein compare
MMP_RS07635 -3.3 -11.5 MogA/MoaB family molybdenum cofactor biosynthesis protein compare
MMP_RS06720 -3.3 -11.3 response regulator transcription factor compare
MMP_RS07365 -3.3 -17.2 2-phosphoglycerate kinase compare
MMP_RS03640 -3.2 -6.6 archaeal proteasome endopeptidase complex subunit beta compare
MMP_RS06345 -3.2 -17.2 formate dehydrogenase accessory sulfurtransferase FdhD compare
MMP_RS01500 -3.2 -5.6 CBS domain-containing protein compare
MMP_RS01700 -3.2 -1.3 dihydroxy-acid dehydratase compare
MMP_RS08165 -3.2 -5.2 phosphoglycerate dehydrogenase compare
MMP_RS08790 -3.1 -5.3 translation initiation factor IF-2 subunit alpha compare
MMP_RS04900 -3.0 -23.8 hypothetical protein compare
MMP_RS03435 -2.9 -2.5 ketol-acid reductoisomerase compare
MMP_RS06975 -2.8 -4.4 sulfide-dependent adenosine diphosphate thiazole synthase compare
MMP_RS01455 -2.7 -9.4 nickel pincer cofactor biosynthesis protein LarC compare
MMP_RS06730 -2.6 -3.6 phosphopantothenate/pantothenate synthetase compare
MMP_RS06705 -2.5 -8.8 formate/nitrite transporter family protein compare
MMP_RS05265 -2.5 -3.9 2-isopropylmalate synthase compare
MMP_RS07845 -2.5 -5.1 LL-diaminopimelate aminotransferase compare
MMP_RS08715 -2.5 -3.0 formylmethanofuran dehydrogenase subunit B compare
MMP_RS06175 -2.5 -11.0 winged helix-turn-helix transcriptional regulator compare
MMP_RS04215 -2.5 -9.3 nickel pincer cofactor biosynthesis protein LarB compare
MMP_RS06375 -2.5 -6.9 ATP-dependent sacrificial sulfur transferase LarE compare
MMP_RS07730 -2.5 -3.1 pyruvate synthase subunit beta compare
MMP_RS07185 -2.4 -16.2 pyridoxal phosphate-dependent aminotransferase compare
MMP_RS00695 -2.4 -2.0 biotin--[acetyl-CoA-carboxylase] ligase compare
MMP_RS06270 -2.3 -6.8 TIGR00300 family protein compare
MMP_RS07525 -2.3 -12.8 4Fe-4S binding protein compare
MMP_RS00040 -2.3 -5.4 TIGR03576 family pyridoxal phosphate-dependent enzyme compare
MMP_RS06340 -2.3 -9.5 phosphoadenosine phosphosulfate reductase family protein compare
MMP_RS05875 -2.2 -7.7 hydroxyethylthiazole kinase compare
MMP_RS05920 -2.2 -1.2 50S ribosomal protein L37e compare
MMP_RS07445 -2.2 -7.0 helix-turn-helix domain-containing protein compare
MMP_RS03450 -2.2 -4.4 glycine synthesis protein GlyXS (from data) compare
MMP_RS06105 -2.2 -7.8 hydrogenase maturation peptidase HycI compare
MMP_RS06840 -2.1 -1.9 DNA-directed RNA polymerase subunit N compare
MMP_RS03025 -2.1 -6.9 molybdenum cofactor guanylyltransferase compare
MMP_RS04605 -2.0 -7.6 cobalt ECF transporter T component CbiQ compare
MMP_RS02345 -2.0 -4.9 GTP-dependent dephospho-CoA kinase family protein compare
MMP_RS06400 -2.0 -3.2 4Fe-4S binding protein compare
MMP_RS07735 -2.0 -1.6 2-ketoisovalerate ferredoxin oxidoreductase subunit alpha compare
MMP_RS04870 -1.9 -7.5 TIGR02253 family HAD-type hydrolase compare
MMP_RS08745 -1.9 -9.7 CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase compare
MMP_RS00685 -1.9 -6.8 2-phospho-L-lactate guanylyltransferase compare
MMP_RS03035 -1.9 -5.2 4-hydroxy-tetrahydrodipicolinate synthase compare
MMP_RS01365 -1.9 -6.9 archaeal proteasome endopeptidase complex subunit alpha compare
MMP_RS07380 -1.9 -4.0 transcription elongation factor Spt5 compare
MMP_RS05765 -1.9 -7.1 M42 family metallopeptidase compare
MMP_RS01380 -1.8 -7.1 PHP domain-containing protein compare
MMP_RS06295 -1.8 -8.5 methanogenesis marker 14 protein compare
MMP_RS00455 -1.8 -10.3 orotate phosphoribosyltransferase-like protein compare
MMP_RS03960 -1.7 -2.0 hypothetical protein compare
MMP_RS05930 -1.7 -3.4 3-isopropylmalate dehydratase large subunit compare
MMP_RS00295 -1.7 -3.7 gamma carbonic anhydrase family protein compare
MMP_RS01190 -1.7 -7.6 cadmium-translocating P-type ATPase compare
MMP_RS01195 -1.7 -2.2 metalloregulator ArsR/SmtB family transcription factor compare
MMP_RS02010 -1.7 -7.3 PHP domain-containing protein compare
MMP_RS06120 -1.7 -3.6 UPF0147 family protein compare
MMP_RS07605 -1.6 -5.5 diadenylate cyclase compare
MMP_RS05540 -1.6 -3.9 hypothetical protein compare
MMP_RS01610 -1.6 -3.8 hypothetical protein compare
MMP_RS08720 -1.6 -2.7 4Fe-4S binding protein compare
MMP_RS00300 -1.5 -1.2 6 7-dimethyl-8-ribityllumazine synthase compare
MMP_RS08460 -1.5 -2.8 proteasome-activating nucleotidase compare
MMP_RS04890 -1.5 -1.3 adenylyltransferase/cytidyltransferase family protein compare
MMP_RS02240 -1.5 -4.7 methanogenesis marker 7 protein compare
MMP_RS01220 -1.5 -8.7 hypothetical protein compare
MMP_RS05430 -1.4 -5.0 TIGR00288 family NYN domain-containing protein compare
MMP_RS09055 -1.4 -1.8 CAP domain-containing protein compare
MMP_RS02355 -1.4 -3.1 30S ribosomal protein S27ae compare
MMP_RS02145 -1.4 -8.3 winged helix-turn-helix transcriptional regulator compare
MMP_RS08435 -1.4 -3.0 Era-like GTP-binding protein compare
MMP_RS08300 -1.4 -1.5 metal-sulfur cluster assembly factor compare
MMP_RS03110 -1.4 -4.7 glycosyltransferase family 2 protein compare
MMP_RS06230 -1.4 -3.1 helix-turn-helix domain-containing protein compare
MMP_RS06020 -1.3 -5.0 archaeoflavoprotein AfpA compare
MMP_RS03445 -1.3 -1.5 methanogenesis marker 17 protein compare
MMP_RS08320 -1.3 -4.9 molybdopterin molybdotransferase MoeA compare
MMP_RS00720 -1.3 -7.6 metal-dependent hydrolase compare
MMP_RS05925 -1.3 -3.4 small nuclear ribonucleoprotein compare
MMP_RS00290 -1.3 -6.7 hypothetical protein compare
MMP_RS01325 -1.2 -2.9 dihydroneopterin aldolase family protein compare
MMP_RS07860 -1.2 -1.4 hypothetical protein compare
MMP_RS06285 -1.2 -3.7 precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT compare
MMP_RS01265 -1.2 -2.3 hypothetical protein compare
MMP_RS04620 -1.2 -6.7 cobalt transporter CbiM compare
MMP_RS01745 -1.2 -4.6 AMP phosphorylase compare
MMP_RS01445 -1.2 -8.4 hypothetical protein compare
MMP_RS08635 -1.2 -2.1 UbiA family prenyltransferase compare
MMP_RS01225 -1.2 -4.9 DUF5379 domain-containing protein compare
MMP_RS02165 -1.2 -5.1 tRNA-dihydrouridine synthase compare
MMP_RS02235 -1.1 -6.3 CBS domain-containing protein compare
MMP_RS02195 -1.1 -3.7 tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase compare
MMP_RS04615 -1.1 -4.2 PDGLE domain-containing protein compare
MMP_RS07710 -1.1 -5.9 cell division protein FtsZ compare
MMP_RS06895 -1.1 -1.5 selenocysteine-specific translation elongation factor compare
MMP_RS04780 -1.1 -2.6 ribonuclease P compare
MMP_RS03145 -1.1 -4.0 fibrillarin-like rRNA/tRNA 2'-O-methyltransferase compare
MMP_RS00750 -1.1 -1.9 fumarate hydratase compare
MMP_RS05285 -1.0 -6.3 MMPL family transporter compare
MMP_RS03600 -1.0 -2.5 triose-phosphate isomerase compare
MMP_RS05550 -1.0 -0.7 cation:proton antiporter compare
MMP_RS07575 -1.0 -5.7 RNA ligase partner protein compare
MMP_RS07200 -1.0 -4.4 [5-(aminomethyl)furan-3-yl]methyl phosphate kinase compare
MMP_RS02280 -1.0 -1.1 DUF211 domain-containing protein compare
MMP_RS02340 -1.0 -1.8 DNA-directed RNA polymerase subunit E'' compare
MMP_RS08650 -1.0 -2.7 glutamine--fructose-6-phosphate transaminase (isomerizing) compare
MMP_RS00620 -1.0 -5.5 4Fe-4S binding protein compare
MMP_RS06630 -1.0 -0.9 UPF0058 family protein compare
MMP_RS06625 -1.0 -2.5 DNA primase compare
MMP_RS05280 -1.0 -5.8 COG1361 S-layer family protein compare
MMP_RS05845 -0.9 -2.0 tRNA-intron lyase compare
MMP_RS07705 -0.9 -5.4 transcriptional regulator compare
MMP_RS07090 -0.9 -5.1 tRNA (adenine-N1)-methyltransferase compare
MMP_RS01755 -0.9 -1.7 DUF2097 domain-containing protein compare
MMP_RS03250 -0.9 -1.7 MJ1244 family protein compare
MMP_RS03555 -0.9 -5.5 transcriptional regulator compare
MMP_RS04090 -0.9 -2.6 hypothetical protein compare
MMP_RS07580 -0.9 -3.1 DUF356 domain-containing protein compare
MMP_RS06925 -0.9 -1.7 ribonuclease VapC4 compare
MMP_RS03305 -0.9 -4.0 winged helix-turn-helix domain-containing protein compare
MMP_RS01925 -0.9 -5.7 DUF1616 domain-containing protein compare
MMP_RS05505 -0.9 -5.7 class IV adenylate cyclase compare
MMP_RS01830 -0.9 -1.5 tRNA-Val compare
MMP_RS07535 -0.9 -4.5 4Fe-4S binding protein compare
MMP_RS00555 -0.9 -4.9 MFS transporter compare
MMP_RS06130 -0.9 -2.5 peptidylprolyl isomerase compare
MMP_RS07955 -0.8 -3.5 FumA C-terminus/TtdB family hydratase beta subunit compare
MMP_RS01005 -0.8 -1.4 riboflavin synthase compare
MMP_RS01240 -0.8 -1.0 7-cyano-7-deazaguanine synthase QueC compare
MMP_RS01720 -0.8 -1.1 replication factor C large subunit compare
MMP_RS08195 -0.8 -5.9 hypothetical protein compare
MMP_RS07545 -0.8 -1.2 HTH domain-containing protein compare
MMP_RS09020 -0.8 -1.2 hypothetical protein compare
MMP_RS04695 -0.8 -4.7 selenide water dikinase SelD compare
MMP_RS07410 -0.8 -5.9 4-demethylwyosine synthase TYW1 compare
MMP_RS01900 -0.8 -6.7 hypothetical protein compare
MMP_RS05425 -0.8 -3.2 monovalent cation/H+ antiporter complex subunit F compare
MMP_RS07005 -0.8 -0.6 4Fe-4S binding protein compare
MMP_RS04955 -0.8 -3.1 DNA topoisomerase I compare
MMP_RS03140 -0.8 -5.4 hypothetical protein compare
MMP_RS04125 -0.8 -2.4 TetR/AcrR family transcriptional regulator compare
MMP_RS03485 -0.8 -3.7 TIGR00267 family protein compare
MMP_RS01985 -0.8 -2.1 F420-dependent methylenetetrahydromethanopterin dehydrogenase compare
MMP_RS04885 -0.8 -5.8 sulfite exporter TauE/SafE family protein compare
MMP_RS01020 -0.8 -1.1 3 4-dihydroxy-2-butanone-4-phosphate synthase compare
MMP_RS03520 -0.8 -0.9 YwbE family protein compare
MMP_RS05510 -0.7 -2.6 Rrf2 family transcriptional regulator compare
MMP_RS01955 -0.7 -1.8 hypothetical protein compare
MMP_RS07555 -0.7 -0.8 monovalent cation/H+ antiporter subunit E compare
MMP_RS07075 -0.7 -2.8 phosphomannomutase/phosphoglucomutase compare
MMP_RS01960 -0.7 -0.9 hypothetical protein compare
MMP_RS06215 -0.7 -2.7 30S ribosomal protein S6e compare
MMP_RS03080 -0.7 -2.4 universal stress protein compare
MMP_RS01665 -0.7 -3.5 DUF2111 domain-containing protein compare
MMP_RS07960 -0.7 -3.3 sugar phosphate isomerase/epimerase compare
MMP_RS06675 -0.7 -4.5 ADP-specific phosphofructokinase compare
MMP_RS00060 -0.7 -1.4 3-dehydroquinate synthase II compare
MMP_RS01800 -0.7 -3.1 TIGR00303 family protein compare
MMP_RS05250 -0.7 -1.0 NFYB/HAP3 family transcription factor subunit compare
MMP_RS06200 -0.7 -4.2 M24 family metallopeptidase compare
MMP_RS00110 -0.7 -1.8 hypothetical protein compare
MMP_RS03580 -0.7 -1.9 signal recognition particle-docking protein FtsY compare
MMP_RS07600 -0.7 -2.1 Ni-sirohydrochlorin a c-diamide synthase compare
MMP_RS02135 -0.7 -2.1 DUF5612 domain-containing protein compare
MMP_RS02780 -0.7 -4.5 hypothetical protein compare
MMP_RS02800 -0.6 -2.2 nucleotidyltransferase domain-containing protein compare
MMP_RS01890 -0.6 -2.4 nucleotide sugar dehydrogenase compare
MMP_RS08820 -0.6 -2.7 hypothetical protein compare
MMP_RS03440 -0.6 -1.0 MoaD/ThiS family protein compare
MMP_RS06930 -0.6 -4.2 MBL fold metallo-hydrolase compare
MMP_RS00535 -0.6 -1.5 TIGR00375 family protein compare
MMP_RS01575 -0.6 -2.9 aldolase compare
MMP_RS02885 -0.6 -4.5 molybdopterin biosynthesis protein compare
MMP_RS05055 -0.6 -4.8 DUF166 domain-containing protein compare
MMP_RS01905 -0.6 -5.0 glycosyltransferase compare
MMP_RS05850 -0.6 -2.2 Ldh family oxidoreductase compare
MMP_RS06885 -0.6 -1.0 50S ribosome-binding GTPase compare
MMP_RS06710 -0.6 -2.1 selenium-binding protein compare
MMP_RS02960 -0.6 -3.4 class I SAM-dependent methyltransferase family protein compare
MMP_RS08615 -0.6 -1.0 flagellar protein G compare
MMP_RS05060 -0.5 -4.1 AAA family ATPase compare
MMP_RS01795 -0.5 -0.8 methanogenesis marker 6 protein compare
MMP_RS04360 -0.5 -1.6 hypothetical protein compare
MMP_RS06865 -0.5 -1.1 HypC/HybG/HupF family hydrogenase formation chaperone compare
MMP_RS05090 -0.5 -2.8 CO dehydrogenase/CO-methylating acetyl-CoA synthase complex subunit beta compare
MMP_RS05095 -0.5 -3.4 CO dehydrogenase/acetyl-CoA synthase complex subunit epsilon compare
MMP_RS01915 -0.5 -4.4 DUF354 domain-containing protein compare


Specific Phenotypes

For 1 genes in this experiment

For nutrient t1 L-Histidine in Methanococcus maripaludis S2

For nutrient t1 L-Histidine across organisms