Experiment set8H40 for Pseudomonas stutzeri RCH2

Compare to:

RCH2 defined media with methylglyoxal 0.01 vol%

200 most important genes:

  gene name fitness t score description  
Psest_2071 -7.8 -7.7 hydroxyacylglutathione hydrolase conserved
Psest_3648 -7.1 -4.9 anthranilate phosphoribosyltransferase compare
Psest_3650 -6.9 -9.5 anthranilate synthase component I, non-proteobacterial lineages compare
Psest_2584 -6.9 -4.8 Phosphoribosylanthranilate isomerase compare
Psest_3120 -6.9 -8.2 lactoylglutathione lyase conserved
Psest_3866 -6.8 -15.8 threonine ammonia-lyase, biosynthetic, long form compare
Psest_3647 -6.7 -8.0 Indole-3-glycerol phosphate synthase compare
Psest_0952 -6.6 -4.6 Uncharacterized conserved protein compare
Psest_0152 -6.6 -7.8 Imidazoleglycerol-phosphate dehydratase compare
Psest_0153 -6.4 -13.0 imidazole glycerol phosphate synthase, glutamine amidotransferase subunit compare
Psest_0279 -6.3 -8.5 methionine biosynthesis protein MetW compare
Psest_0155 -6.3 -7.5 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
Psest_3384 -6.1 -8.4 glutamate 5-kinase compare
Psest_0508 -5.8 -8.0 gamma-glutamyl phosphate reductase compare
Psest_3864 -5.8 -15.5 Histidinol-phosphatase (EC:3.1.3.15) (from data) compare
Psest_0325 -5.7 -17.3 Putative threonine efflux protein compare
Psest_3298 -5.7 -12.8 histidinol dehydrogenase compare
Psest_2590 -5.7 -2.1 3-isopropylmalate dehydratase, small subunit compare
Psest_3226 -5.7 -2.1 Predicted membrane protein compare
Psest_0296 -5.6 -7.7 glutathione synthetase, prokaryotic compare
Psest_2578 -5.6 -16.5 O-succinylhomoserine sulfhydrylase compare
Psest_2034 -5.6 -13.5 ATPase related to the helicase subunit of the Holliday junction resolvase conserved
Psest_2591 -5.5 -5.4 3-isopropylmalate dehydratase, large subunit compare
Psest_3299 -5.4 -15.7 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
Psest_0280 -5.4 -19.7 homoserine O-acetyltransferase compare
Psest_0062 -5.2 -11.7 tryptophan synthase, alpha subunit compare
Psest_1452 -5.2 -8.7 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase compare
Psest_1772 -5.2 -5.0 Aspartate/tyrosine/aromatic aminotransferase compare
Psest_2088 -5.2 -4.0 Uncharacterized protein conserved in bacteria compare
Psest_0954 -5.0 -10.1 Fe-S oxidoreductase compare
Psest_3944 -4.9 -3.4 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
Psest_0537 -4.9 -3.4 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase compare
Psest_0326 -4.9 -14.7 Taurine catabolism dioxygenase TauD, TfdA family. compare
Psest_3303 -4.8 -8.0 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) compare
Psest_0063 -4.7 -8.5 tryptophan synthase, beta subunit compare
Psest_1295 -4.7 -6.5 Aspartate/tyrosine/aromatic aminotransferase compare
Psest_0953 -4.7 -11.6 iron-sulfur cluster-binding protein compare
Psest_3304 -4.7 -6.4 ABC-type transport system involved in resistance to organic solvents, auxiliary component compare
Psest_0170 -4.6 -9.9 5,10-methenyltetrahydrofolate synthetase compare
Psest_3307 -4.6 -10.6 ABC-type transport system involved in resistance to organic solvents, ATPase component compare
Psest_2579 -4.3 -3.0 amidophosphoribosyltransferase compare
Psest_3649 -4.3 -13.3 glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase compare
Psest_2589 -4.3 -12.3 3-isopropylmalate dehydrogenase compare
Psest_1496 -4.3 -2.8 Holliday junction DNA helicase, RuvA subunit compare
Psest_1473 -4.3 -9.0 phosphoribosylglycinamide formyltransferase, formyltetrahydrofolate-dependent compare
Psest_2712 -4.2 -7.6 Surface lipoprotein compare
Psest_0687 -4.1 -8.3 ATP phosphoribosyltransferase, regulatory subunit compare
Psest_3305 -4.1 -10.3 ABC-type transport system involved in resistance to organic solvents, periplasmic component compare
Psest_2329 -4.0 -17.6 Transcriptional regulator compare
Psest_3306 -4.0 -8.0 conserved hypothetical integral membrane protein compare
Psest_3943 -3.9 -3.8 Phosphoribosyl-AMP cyclohydrolase compare
Psest_3998 -3.9 -3.8 glutamate--cysteine ligase compare
Psest_1037 -3.7 -4.7 acetolactate synthase, small subunit compare
Psest_0313 -3.7 -4.4 5,10-methylenetetrahydrofolate reductase, prokaryotic form compare
Psest_1509 -3.7 -13.0 quinolinate synthetase complex, A subunit compare
Psest_0411 -3.6 -14.0 biotin synthetase compare
Psest_0266 -3.5 -10.3 thiamine biosynthesis protein ThiS compare
Psest_2872 -3.4 -2.4 protein RecA compare
Psest_1013 -3.4 -2.4 phosphoribosylamine--glycine ligase compare
Psest_3159 -3.2 -7.8 phosphoribosylformylglycinamidine synthase, single chain form compare
Psest_0306 -3.2 -18.0 adenosylmethionine-8-amino-7-oxononanoate transaminase compare
Psest_3129 -3.2 -3.0 tyrosine recombinase XerD compare
Psest_0466 -3.1 -4.8 Lipopolysaccharide kinase (Kdo/WaaP) family. compare
Psest_1115 -3.1 -4.4 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 compare
Psest_0498 -3.1 -2.7 ribosome small subunit-dependent GTPase A compare
Psest_1474 -3.0 -2.1 phosphoribosylaminoimidazole synthetase compare
Psest_0267 -3.0 -12.9 Uncharacterized enzyme of thiazole biosynthesis compare
Psest_3810 -3.0 -2.0 orotate phosphoribosyltransferase compare
Psest_0718 -2.9 -6.0 nicotinate-nucleotide pyrophosphorylase compare
Psest_3818 -2.9 -8.5 endoribonuclease L-PSP, putative compare
Psest_3297 -2.8 -13.7 histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) compare
Psest_4098 -2.8 -5.6 Superfamily I DNA and RNA helicases compare
Psest_0489 -2.7 -2.6 phosphoserine phosphatase SerB compare
Psest_3767 -2.7 -4.9 tyrosine recombinase XerC compare
Psest_0193 -2.7 -2.0 conserved hypothetical protein compare
Psest_3721 -2.6 -8.3 Malic enzyme compare
Psest_1724 -2.5 -5.1 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) compare
Psest_0477 -2.4 -13.4 thiamine biosynthesis protein ThiC compare
Psest_1505 -2.3 -3.6 Organic radical activating enzymes compare
Psest_2651 -2.3 -5.4 DNA topoisomerase I, bacterial compare
Psest_0415 -2.3 -6.8 dethiobiotin synthase compare
Psest_3573 -2.3 -6.6 dTDP-4-dehydrorhamnose reductase compare
Psest_4219 -2.3 -3.5 DNA polymerase I compare
Psest_0414 -2.2 -6.0 biotin biosynthesis protein BioC compare
Psest_3766 -2.0 -2.5 Uncharacterized protein conserved in bacteria compare
Psest_2324 -2.0 -14.2 hypothetical protein compare
Psest_1242 -2.0 -3.4 tRNA-guanine transglycosylase, queuosine-34-forming compare
Psest_2714 -2.0 -2.8 7-cyano-7-deazaguanine reductase compare
Psest_1012 -2.0 -5.2 Signal transduction histidine kinase compare
Psest_0412 -2.0 -9.8 8-amino-7-oxononanoate synthase compare
Psest_0951 -2.0 -10.7 FAD/FMN-containing dehydrogenases compare
Psest_0393 -1.9 -6.5 Methylase of chemotaxis methyl-accepting proteins compare
Psest_3092 -1.9 -1.8 ribonuclease III, bacterial compare
Psest_2104 -1.9 -3.2 IscR-regulated protein YhgI compare
Psest_4363 -1.8 -9.1 ATPases involved in chromosome partitioning compare
Psest_2946 -1.8 -4.2 septum site-determining protein MinD compare
Psest_2857 -1.8 -9.9 Rad3-related DNA helicases conserved
Psest_2325 -1.8 -10.9 alpha-L-glutamate ligase-related protein compare
Psest_3883 -1.8 -6.9 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain compare
Psest_0536 -1.8 -3.8 thiamine-phosphate pyrophosphorylase compare
Psest_0413 -1.7 -5.8 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) compare
Psest_1277 -1.7 -10.7 2-isopropylmalate synthase, yeast type compare
Psest_0445 -1.7 -11.5 PAS domain S-box/diguanylate cyclase (GGDEF) domain compare
Psest_3862 -1.7 -10.9 phosphoenolpyruvate-protein phosphotransferase compare
Psest_1296 -1.7 -9.4 excinuclease ABC, B subunit conserved
Psest_2323 -1.6 -10.7 Uncharacterized protein conserved in archaea compare
Psest_1511 -1.6 -2.9 Predicted redox protein, regulator of disulfide bond formation compare
Psest_3123 -1.6 -3.3 dihydroorotase, homodimeric type compare
Psest_1486 -1.6 -5.1 hypothetical protein compare
Psest_0212 -1.6 -1.5 exodeoxyribonuclease V, gamma subunit compare
Psest_2333 -1.6 -1.5 Protein of unknown function (DUF3359). compare
Psest_2862 -1.5 -8.8 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 compare
Psest_0442 -1.5 -5.0 ATPases of the AAA+ class compare
Psest_0281 -1.5 -5.5 Dynamin family. compare
Psest_1679 -1.5 -1.6 ribonuclease, Rne/Rng family compare
Psest_0004 -1.5 -9.8 recF protein conserved
Psest_1686 -1.5 -3.9 fatty acid/phospholipid synthesis protein PlsX compare
Psest_3576 -1.5 -11.9 excinuclease ABC, A subunit conserved
Psest_1947 -1.5 -1.4 dihydroorotate dehydrogenase, subfamily 2 compare
Psest_0837 -1.4 -3.7 Putative lipid carrier protein compare
Psest_0691 -1.4 -8.5 ribonuclease R compare
Psest_1506 -1.4 -4.8 queuosine biosynthesis protein QueC compare
Psest_0955 -1.4 -3.6 D,L-lactate:H+ symporter (from data) compare
Psest_1292 -1.4 -7.4 monothiol glutaredoxin, Grx4 family compare
Psest_2090 -1.4 -2.8 Protein of unknown function (DUF2970). compare
Psest_3519 -1.3 -2.8 Uncharacterized conserved protein compare
Psest_1813 -1.3 -9.1 pseudaminic acid biosynthesis-associated protein PseG compare
Psest_3884 -1.3 -1.1 Signal transduction histidine kinase compare
Psest_3419 -1.3 -7.4 Predicted transcriptional regulators compare
Psest_0137 -1.3 -7.3 amine acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family compare
Psest_2327 -1.3 -5.4 phosphoserine phosphatase/homoserine phosphotransferase bifunctional protein compare
Psest_2545 -1.3 -4.2 recombination protein RecR compare
Psest_3732 -1.2 -6.3 polyphosphate kinase 1 compare
Psest_0136 -1.2 -10.1 amine acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family compare
Psest_3904 -1.2 -1.1 hypothetical protein compare
Psest_2331 -1.2 -6.2 phospho-2-dehydro-3-deoxyheptonate aldolase compare
Psest_3464 -1.2 -6.6 Signal transduction histidine kinase compare
Psest_3988 -1.2 -5.6 phosphoenolpyruvate carboxykinase (ATP) compare
Psest_0309 -1.2 -1.7 RND family efflux transporter, MFP subunit compare
Psest_4085 -1.2 -8.2 Biotin carboxylase compare
Psest_3178 -1.2 -4.3 formyltetrahydrofolate deformylase compare
Psest_3536 -1.2 -1.5 hypothetical protein compare
Psest_2067 -1.2 -1.5 ABC-type oligopeptide transport system, periplasmic component compare
Psest_1366 -1.1 -1.3 hypothetical protein compare
Psest_0138 -1.1 -7.5 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain compare
Psest_1132 -1.1 -3.6 mutator mutT protein compare
Psest_4191 -1.1 -2.2 Transcriptional regulator compare
Psest_3990 -1.1 -6.2 PAP2 superfamily. compare
Psest_1163 -1.1 -3.3 diguanylate cyclase (GGDEF) domain compare
Psest_3878 -1.1 -2.7 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain compare
Psest_1031 -1.1 -6.4 Uncharacterized protein conserved in bacteria compare
Psest_3317 -1.1 -4.7 Phosphotransferase System HPr (HPr) Family compare
Psest_3931 -1.1 -4.5 Signal transduction histidine kinase, nitrogen specific compare
Psest_0133 -1.1 -1.8 type VI secretion protein, VC_A0107 family compare
Psest_3565 -1.0 -1.0 hypothetical protein compare
Psest_2810 -1.0 -4.7 5'/3'-nucleotidase SurE compare
Psest_4396 -1.0 -6.1 Site-specific recombinases, DNA invertase Pin homologs compare
Psest_3720 -1.0 -8.6 penicillin-binding protein, 1A family compare
Psest_2379 -1.0 -7.7 PAS domain S-box compare
Psest_0182 -1.0 -4.3 glycine cleavage system H protein compare
Psest_0515 -1.0 -2.3 rare lipoprotein A compare
Psest_0327 -1.0 -4.4 Transcriptional regulator compare
Psest_2259 -1.0 -7.0 excinuclease ABC, C subunit conserved
Psest_4345 -1.0 -6.3 Bacteriophytochrome (light-regulated signal transduction histidine kinase) compare
Psest_1663 -1.0 -1.8 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes compare
Psest_1704 -1.0 -1.3 Dehydrogenases (flavoproteins) compare
Psest_2680 -0.9 -4.5 transcriptional regulator, BolA protein family compare
Psest_0708 -0.9 -1.6 outer membrane assembly lipoprotein YfiO compare
Psest_3090 -0.9 -5.3 DNA repair protein RecO compare
Psest_0139 -0.9 -3.4 ABC-type histidine transport system, ATPase component compare
Psest_0359 -0.9 -2.2 Transcriptional regulators compare
Psest_3664 -0.9 -1.2 Predicted phosphotransferase related to Ser/Thr protein kinases compare
Psest_2605 -0.9 -1.2 transcriptional activator RfaH compare
Psest_4070 -0.9 -5.6 PAS domain S-box compare
Psest_2864 -0.9 -4.1 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain compare
Psest_3710 -0.9 -6.8 glutamate synthase small subunit family protein, proteobacterial compare
Psest_2863 -0.9 -4.3 Transcriptional regulator compare
Psest_0457 -0.9 -2.3 Lipopolysaccharide kinase (Kdo/WaaP) family. compare
Psest_0744 -0.9 -0.8 Uncharacterized conserved protein compare
Psest_2896 -0.9 -2.1 hypothetical protein compare
Psest_2581 -0.9 -1.8 Uncharacterized protein conserved in bacteria compare
Psest_4201 -0.9 -1.4 general secretion pathway protein F compare
Psest_1870 -0.9 -1.4 Transcriptional regulators compare
Psest_0285 -0.8 -5.5 pilus retraction protein PilT compare
Psest_4086 -0.8 -5.1 Transcriptional regulator compare
Psest_0533 -0.8 -4.0 Sel1 repeat. compare
Psest_4084 -0.8 -6.5 oxaloacetate decarboxylase alpha subunit compare
Psest_1640 -0.8 -6.4 (p)ppGpp synthetase, RelA/SpoT family compare
Psest_0013 -0.8 -5.2 Lauroyl/myristoyl acyltransferase compare
Psest_2424 -0.8 -1.6 K+ transport systems, NAD-binding component compare
Psest_1249 -0.8 -4.1 serine O-acetyltransferase compare
Psest_0120 -0.8 -3.7 hypothetical protein compare
Psest_3391 -0.8 -1.6 Uncharacterized protein conserved in bacteria compare
Psest_2334 -0.8 -6.5 Uncharacterized protein conserved in bacteria compare
Psest_3777 -0.8 -2.1 diguanylate cyclase (GGDEF) domain compare
Psest_0297 -0.8 -2.5 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain compare
Psest_2630 -0.8 -1.8 hypothetical protein compare
Psest_3645 -0.8 -5.7 Predicted redox protein, regulator of disulfide bond formation compare
Psest_3711 -0.8 -6.3 Glutamate synthase domain 2 compare
Psest_2719 -0.8 -1.7 acetylornithine and succinylornithine aminotransferases/succinylornithine transaminase family compare


Specific Phenotypes

For 7 genes in this experiment

For stress methylglyoxal in Pseudomonas stutzeri RCH2

For stress methylglyoxal across organisms