Experiment set8H34 for Pseudomonas stutzeri RCH2

Compare to:

RCH2 defined media with Polymyxin B sulfate 0.0001 mg/ml

200 most important genes:

  gene name fitness t score description  
Psest_0954 -7.3 -10.0 Fe-S oxidoreductase compare
Psest_0155 -6.8 -4.7 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
Psest_3647 -6.3 -8.7 Indole-3-glycerol phosphate synthase compare
Psest_0153 -6.2 -15.1 imidazole glycerol phosphate synthase, glutamine amidotransferase subunit compare
Psest_3864 -6.2 -16.5 Histidinol-phosphatase (EC:3.1.3.15) (from data) compare
Psest_0152 -6.0 -7.5 Imidazoleglycerol-phosphate dehydratase compare
Psest_0279 -5.9 -9.1 methionine biosynthesis protein MetW compare
Psest_1473 -5.8 -8.9 phosphoribosylglycinamide formyltransferase, formyltetrahydrofolate-dependent compare
Psest_2584 -5.8 -8.3 Phosphoribosylanthranilate isomerase compare
Psest_3866 -5.8 -20.7 threonine ammonia-lyase, biosynthetic, long form compare
Psest_2590 -5.7 -1.6 3-isopropylmalate dehydratase, small subunit compare
Psest_3226 -5.6 -1.6 Predicted membrane protein compare
Psest_0411 -5.6 -12.5 biotin synthetase compare
Psest_0952 -5.6 -5.2 Uncharacterized conserved protein compare
Psest_0062 -5.5 -11.8 tryptophan synthase, alpha subunit compare
Psest_3648 -5.5 -11.2 anthranilate phosphoribosyltransferase compare
Psest_3650 -5.4 -16.8 anthranilate synthase component I, non-proteobacterial lineages compare
Psest_0687 -5.3 -12.4 ATP phosphoribosyltransferase, regulatory subunit compare
Psest_0170 -5.3 -10.8 5,10-methenyltetrahydrofolate synthetase compare
Psest_2578 -5.2 -17.6 O-succinylhomoserine sulfhydrylase compare
Psest_3298 -5.1 -13.6 histidinol dehydrogenase compare
Psest_3306 -5.1 -6.1 conserved hypothetical integral membrane protein compare
Psest_3384 -5.0 -12.2 glutamate 5-kinase compare
Psest_0508 -5.0 -10.2 gamma-glutamyl phosphate reductase compare
Psest_3299 -5.0 -17.3 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
Psest_0280 -5.0 -17.3 homoserine O-acetyltransferase compare
Psest_3818 -4.8 -10.3 endoribonuclease L-PSP, putative compare
Psest_0953 -4.7 -14.1 iron-sulfur cluster-binding protein compare
Psest_3721 -4.5 -10.0 Malic enzyme compare
Psest_0063 -4.5 -9.5 tryptophan synthase, beta subunit compare
Psest_0306 -4.5 -21.3 adenosylmethionine-8-amino-7-oxononanoate transaminase compare
Psest_0325 -4.4 -15.2 Putative threonine efflux protein compare
Psest_2579 -4.3 -3.0 amidophosphoribosyltransferase compare
Psest_1295 -4.3 -7.7 Aspartate/tyrosine/aromatic aminotransferase compare
Psest_0413 -4.3 -9.4 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) compare
Psest_3297 -4.3 -12.0 histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) compare
Psest_2088 -4.2 -3.5 Uncharacterized protein conserved in bacteria compare
Psest_3305 -4.2 -10.4 ABC-type transport system involved in resistance to organic solvents, periplasmic component compare
Psest_2589 -4.2 -12.3 3-isopropylmalate dehydrogenase compare
Psest_0415 -4.1 -6.3 dethiobiotin synthase compare
Psest_3307 -4.1 -10.8 ABC-type transport system involved in resistance to organic solvents, ATPase component compare
Psest_0412 -4.0 -13.5 8-amino-7-oxononanoate synthase compare
Psest_4086 -4.0 -15.3 Transcriptional regulator compare
Psest_2329 -3.9 -21.4 Transcriptional regulator compare
Psest_1452 -3.9 -13.8 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase compare
Psest_2333 -3.9 -1.5 Protein of unknown function (DUF3359). compare
Psest_0326 -3.9 -12.1 Taurine catabolism dioxygenase TauD, TfdA family. compare
Psest_0951 -3.8 -11.9 FAD/FMN-containing dehydrogenases compare
Psest_3303 -3.8 -7.8 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) compare
Psest_0955 -3.7 -6.7 D,L-lactate:H+ symporter (from data) compare
Psest_3998 -3.7 -4.4 glutamate--cysteine ligase compare
Psest_0718 -3.7 -7.0 nicotinate-nucleotide pyrophosphorylase compare
Psest_1772 -3.6 -6.7 Aspartate/tyrosine/aromatic aminotransferase compare
Psest_3944 -3.6 -2.7 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
Psest_1724 -3.5 -5.4 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) compare
Psest_0313 -3.5 -4.8 5,10-methylenetetrahydrofolate reductase, prokaryotic form compare
Psest_2104 -3.5 -2.4 IscR-regulated protein YhgI compare
Psest_2591 -3.5 -4.4 3-isopropylmalate dehydratase, large subunit compare
Psest_0267 -3.5 -15.7 Uncharacterized enzyme of thiazole biosynthesis compare
Psest_0993 -3.5 -12.8 Glucose-6-phosphate isomerase compare
Psest_1509 -3.4 -12.3 quinolinate synthetase complex, A subunit compare
Psest_0414 -3.4 -6.7 biotin biosynthesis protein BioC compare
Psest_2712 -3.4 -6.9 Surface lipoprotein compare
Psest_1813 -3.4 -12.1 pseudaminic acid biosynthesis-associated protein PseG compare
Psest_4085 -3.4 -19.2 Biotin carboxylase compare
Psest_0445 -3.4 -17.3 PAS domain S-box/diguanylate cyclase (GGDEF) domain compare
Psest_1814 -3.3 -19.6 pseudaminic acid biosynthesis N-acetyl transferase compare
Psest_0466 -3.2 -4.6 Lipopolysaccharide kinase (Kdo/WaaP) family. compare
Psest_2232 -3.2 -16.1 UTP-glucose-1-phosphate uridylyltransferase compare
Psest_4084 -3.2 -19.0 oxaloacetate decarboxylase alpha subunit compare
Psest_0477 -3.2 -17.3 thiamine biosynthesis protein ThiC compare
Psest_2090 -3.2 -3.6 Protein of unknown function (DUF2970). compare
Psest_4298 -3.1 -1.2 Response regulator containing a CheY-like receiver domain and a GGDEF domain compare
Psest_0266 -3.1 -8.8 thiamine biosynthesis protein ThiS compare
Psest_3304 -3.0 -5.9 ABC-type transport system involved in resistance to organic solvents, auxiliary component compare
Psest_0536 -3.0 -6.0 thiamine-phosphate pyrophosphorylase compare
Psest_3649 -3.0 -11.2 glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase compare
Psest_2862 -2.9 -12.5 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 compare
Psest_1012 -2.9 -5.4 Signal transduction histidine kinase compare
Psest_3810 -2.8 -1.9 orotate phosphoribosyltransferase compare
Psest_3322 -2.8 -19.1 TIGR02099 family protein compare
Psest_1115 -2.8 -4.2 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 compare
Psest_1496 -2.8 -1.7 Holliday junction DNA helicase, RuvA subunit compare
Psest_0489 -2.7 -2.6 phosphoserine phosphatase SerB compare
Psest_0498 -2.7 -2.2 ribosome small subunit-dependent GTPase A compare
Psest_1474 -2.7 -2.6 phosphoribosylaminoimidazole synthetase compare
Psest_1679 -2.6 -2.1 ribonuclease, Rne/Rng family compare
Psest_1013 -2.6 -3.9 phosphoribosylamine--glycine ligase compare
Psest_0281 -2.5 -7.3 Dynamin family. compare
Psest_1292 -2.5 -9.8 monothiol glutaredoxin, Grx4 family compare
Psest_3943 -2.3 -3.9 Phosphoribosyl-AMP cyclohydrolase compare
Psest_2945 -2.3 -2.1 septum site-determining protein MinC compare
Psest_0193 -2.3 -1.5 conserved hypothetical protein compare
Psest_1037 -2.2 -3.0 acetolactate synthase, small subunit compare
Psest_0725 -2.2 -2.2 Negative regulator of beta-lactamase expression compare
Psest_1031 -2.2 -10.6 Uncharacterized protein conserved in bacteria compare
Psest_1809 -2.2 -13.4 Membrane protein involved in the export of O-antigen and teichoic acid compare
Psest_1111 -2.2 -5.2 Flp pilus assembly protein TadD, contains TPR repeats compare
Psest_3159 -2.1 -5.7 phosphoribosylformylglycinamidine synthase, single chain form compare
Psest_0296 -2.0 -9.7 glutathione synthetase, prokaryotic compare
Psest_1812 -2.0 -11.1 pseudaminic acid CMP-transferase compare
Psest_2863 -1.9 -3.7 Transcriptional regulator compare
Psest_0537 -1.9 -2.1 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase compare
Psest_0457 -1.9 -4.3 Lipopolysaccharide kinase (Kdo/WaaP) family. compare
Psest_0461 -1.9 -6.5 Glycosyltransferase involved in LPS biosynthesis compare
Psest_3883 -1.9 -5.8 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain compare
Psest_1510 -1.9 -5.2 Putative Zn-dependent protease, contains TPR repeats compare
Psest_2327 -1.8 -8.0 phosphoserine phosphatase/homoserine phosphotransferase bifunctional protein compare
Psest_4363 -1.8 -8.4 ATPases involved in chromosome partitioning compare
Psest_3988 -1.8 -6.1 phosphoenolpyruvate carboxykinase (ATP) compare
Psest_2946 -1.8 -4.2 septum site-determining protein MinD compare
Psest_2324 -1.8 -12.9 hypothetical protein compare
Psest_3301 -1.7 -3.4 Predicted transcriptional regulator, BolA superfamily compare
Psest_2325 -1.7 -10.2 alpha-L-glutamate ligase-related protein compare
Psest_0737 -1.7 -0.9 Cu(I)-responsive transcriptional regulator compare
Psest_2872 -1.7 -1.6 protein RecA compare
Psest_3573 -1.7 -4.3 dTDP-4-dehydrorhamnose reductase compare
Psest_3123 -1.7 -3.3 dihydroorotase, homodimeric type compare
Psest_0462 -1.6 -14.8 Lipid A core - O-antigen ligase and related enzymes compare
Psest_2648 -1.6 -2.7 hypothetical protein compare
Psest_1704 -1.6 -1.9 Dehydrogenases (flavoproteins) compare
Psest_2680 -1.6 -6.5 transcriptional regulator, BolA protein family compare
Psest_2323 -1.6 -10.1 Uncharacterized protein conserved in archaea compare
Psest_3338 -1.6 -1.7 Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain compare
Psest_4310 -1.5 -1.4 ABC-type Mn2+/Zn2+ transport systems, permease components compare
Psest_1947 -1.5 -1.1 dihydroorotate dehydrogenase, subfamily 2 compare
Psest_4345 -1.5 -8.7 Bacteriophytochrome (light-regulated signal transduction histidine kinase) compare
Psest_3720 -1.5 -12.1 penicillin-binding protein, 1A family compare
Psest_0297 -1.5 -4.1 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain compare
Psest_1277 -1.5 -8.5 2-isopropylmalate synthase, yeast type compare
Psest_0285 -1.5 -7.5 pilus retraction protein PilT compare
Psest_3419 -1.4 -7.1 Predicted transcriptional regulators compare
Psest_0284 -1.4 -10.2 pyridoxal phosphate enzyme, YggS family compare
Psest_0292 -1.4 -2.6 Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase compare
Psest_1511 -1.4 -2.9 Predicted redox protein, regulator of disulfide bond formation compare
Psest_0393 -1.4 -2.8 Methylase of chemotaxis methyl-accepting proteins compare
Psest_0136 -1.4 -8.8 amine acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family compare
Psest_3288 -1.4 -9.0 type IV-A pilus assembly ATPase PilB compare
Psest_4297 -1.3 -7.7 PAS domain S-box compare
Psest_0182 -1.3 -5.5 glycine cleavage system H protein compare
Psest_3391 -1.3 -2.4 Uncharacterized protein conserved in bacteria compare
Psest_1886 -1.3 -4.2 Uncharacterized protein conserved in bacteria compare
Psest_3931 -1.3 -3.1 Signal transduction histidine kinase, nitrogen specific compare
Psest_2768 -1.3 -2.0 Kef-type K+ transport systems, predicted NAD-binding component compare
Psest_3767 -1.3 -3.4 tyrosine recombinase XerC compare
Psest_0138 -1.3 -9.0 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain compare
Psest_1765 -1.2 -4.6 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains compare
Psest_3092 -1.2 -1.2 ribonuclease III, bacterial compare
Psest_3228 -1.2 -5.8 Zn-dependent protease with chaperone function compare
Psest_0442 -1.2 -4.3 ATPases of the AAA+ class compare
Psest_2864 -1.2 -3.7 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain compare
Psest_4191 -1.2 -2.0 Transcriptional regulator compare
Psest_2809 -1.2 -2.8 protein-L-isoaspartate(D-aspartate) O-methyltransferase compare
Psest_4396 -1.2 -6.1 Site-specific recombinases, DNA invertase Pin homologs compare
Psest_2810 -1.2 -3.5 5'/3'-nucleotidase SurE compare
Psest_1601 -1.2 -1.4 Signal transduction histidine kinase compare
Psest_4005 -1.2 -4.4 Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB compare
Psest_4124 -1.2 -3.4 hypothetical protein compare
Psest_3565 -1.2 -1.1 hypothetical protein compare
Psest_3884 -1.2 -0.8 Signal transduction histidine kinase compare
Psest_4097 -1.2 -7.5 PAS domain S-box/diguanylate cyclase (GGDEF) domain compare
Psest_1049 -1.2 -3.7 Uncharacterized paraquat-inducible protein A compare
Psest_0137 -1.2 -6.7 amine acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family compare
Psest_0722 -1.2 -6.6 Predicted ATPase compare
Psest_1527 -1.1 -8.2 Na+/proline symporter compare
Psest_3860 -1.1 -2.1 Predicted permeases compare
Psest_0120 -1.1 -3.9 hypothetical protein compare
Psest_0491 -1.1 -6.1 PAS domain S-box/diguanylate cyclase (GGDEF) domain compare
Psest_1818 -1.1 -7.6 GDP-mannose 4,6-dehydratase compare
Psest_1837 -1.1 -5.3 Endoglucanase compare
Psest_1132 -1.1 -2.9 mutator mutT protein compare
Psest_2907 -1.1 -1.2 Protein of unknown function (DUF3618). compare
Psest_2458 -1.1 -2.1 MoxR-like ATPases compare
Psest_2646 -1.1 -1.8 SOS regulatory protein LexA compare
Psest_3932 -1.0 -4.4 nitrogen regulation protein NR(I) compare
Psest_1822 -1.0 -4.7 Glycosyltransferases involved in cell wall biogenesis compare
Psest_1167 -1.0 -1.0 hypothetical protein compare
Psest_3562 -1.0 -0.9 ABC-type antimicrobial peptide transport system, ATPase component compare
Psest_0515 -1.0 -2.8 rare lipoprotein A compare
Psest_3809 -1.0 -3.3 hypothetical protein compare
Psest_3129 -1.0 -1.0 tyrosine recombinase XerD compare
Psest_0057 -1.0 -2.7 Predicted transcriptional regulators compare
Psest_1825 -1.0 -6.3 Predicted nucleoside-diphosphate sugar epimerases compare
Psest_1163 -1.0 -3.1 diguanylate cyclase (GGDEF) domain compare
Psest_1819 -1.0 -8.1 Nucleoside-diphosphate-sugar epimerases compare
Psest_3339 -1.0 -2.5 Signal transduction histidine kinase compare
Psest_1505 -0.9 -1.6 Organic radical activating enzymes compare
Psest_2177 -0.9 -2.9 Protein of unknown function (DUF1652). compare
Psest_1144 -0.9 -1.8 AmpG-related permease compare
Psest_3177 -0.9 -1.7 hypothetical protein compare
Psest_3645 -0.9 -6.1 Predicted redox protein, regulator of disulfide bond formation compare
Psest_3836 -0.9 -2.7 L-lactate permease compare
Psest_3990 -0.9 -4.5 PAP2 superfamily. compare
Psest_4391 -0.9 -6.8 ATPases involved in chromosome partitioning compare
Psest_0440 -0.9 -3.5 hypothetical protein compare
Psest_4216 -0.9 -2.8 hypothetical protein compare
Psest_3146 -0.9 -1.0 hypothetical protein compare
Psest_2580 -0.9 -3.0 Uncharacterized membrane protein, required for colicin V production compare
Psest_1817 -0.9 -3.5 hypothetical protein compare
Psest_0464 -0.9 -7.3 Mannosyltransferase OCH1 and related enzymes compare


Specific Phenotypes

For 5 genes in this experiment

For stress Polymyxin B sulfate in Pseudomonas stutzeri RCH2

For stress Polymyxin B sulfate across organisms