Experiment set7S446 for Methanococcus maripaludis JJ

Compare to:

McCas_formate_complete Nitrofurantoin 0.025 mM

200 most important genes:

  gene name fitness t score description  
MMJJ_RS04875 -4.9 -0.5 tRNA-Lys compare
MMJJ_RS07505 -4.9 -0.5 DNA-directed RNA polymerase subunit K compare
MMJJ_RS01810 -4.6 -0.9 methyl coenzyme M reductase system, component A2 compare
MMJJ_RS00525 -4.4 -1.2 Dabb family protein compare
MMJJ_RS04970 -4.3 -1.0 DUF655 domain-containing protein compare
MMJJ_RS01815 -4.3 -2.1 DUF134 domain-containing protein compare
MMJJ_RS04475 -4.2 -1.4 3,4-dihydroxy-2-butanone-4-phosphate synthase compare
MMJJ_RS05380 -4.2 -0.7 hypothetical protein compare
MMJJ_RS06200 -4.1 -1.0 phosphoglycerate dehydrogenase compare
MMJJ_RS08130 -4.1 -0.4 translation initiation factor IF-2 subunit gamma compare
MMJJ_RS02040 -4.0 -1.1 Asp-tRNA(Asn) amidotransferase subunit GatC compare
MMJJ_RS08535 -4.0 -1.3 NOL1/NOP2/sun family putative RNA methylase compare
MMJJ_RS04485 -3.9 -5.0 riboflavin synthase compare
MMJJ_RS01880 -3.8 -1.1 RlmE family RNA methyltransferase compare
MMJJ_RS05590 -3.7 -1.2 homoserine dehydrogenase compare
MMJJ_RS06180 -3.6 -1.1 tryptophan--tRNA ligase compare
MMJJ_RS04975 -3.6 -0.9 glycosyltransferase family 4 protein compare
MMJJ_RS07415 -3.6 -1.0 polyprenyl diphosphate synthase compare
MMJJ_RS06905 -3.5 -0.8 hypothetical protein compare
MMJJ_RS03240 -3.5 -1.3 histone family protein compare
MMJJ_RS07585 -3.5 -8.6 DHH family phosphoesterase compare
MMJJ_RS06665 -3.5 -4.7 DUF3236 domain-containing protein compare
MMJJ_RS09175 -3.4 -0.5 anthranilate synthase component I compare
MMJJ_RS00370 -3.4 -0.7 asparagine synthase (glutamine-hydrolyzing) compare
MMJJ_RS03115 -3.4 -3.2 sulfopyruvate decarboxylase subunit alpha compare
MMJJ_RS06875 -3.4 -0.8 hypothetical protein compare
MMJJ_RS00065 -3.4 -8.0 4Fe-4S dicluster domain-containing protein compare
MMJJ_RS03360 -3.4 -0.5 hypothetical protein compare
MMJJ_RS00935 -3.4 -9.9 nickel pincer cofactor biosynthesis protein LarB compare
MMJJ_RS03865 -3.4 -0.6 phosphoribosyl-AMP cyclohydrolase compare
MMJJ_RS07970 -3.3 -0.6 O-phospho-L-seryl-tRNA:Cys-tRNA synthase compare
MMJJ_RS01405 -3.3 -0.5 proline--tRNA ligase compare
MMJJ_RS07975 -3.3 -7.2 ATP-dependent sacrificial sulfur transferase LarE compare
MMJJ_RS03920 -3.2 -11.6 nickel pincer cofactor biosynthesis protein LarC compare
MMJJ_RS03965 -3.2 -0.6 DNA-directed RNA polymerase subunit L compare
MMJJ_RS06930 -3.2 -0.9 type II methionyl aminopeptidase compare
MMJJ_RS08935 -3.2 -0.5 TIGR00288 family NYN domain-containing protein compare
MMJJ_RS00210 -3.2 -0.8 DUF530 family protein compare
MMJJ_RS04755 -3.2 -9.5 5,10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdB compare
MMJJ_RS03095 -3.2 -0.9 bifunctional N(6)-L-threonylcarbamoyladenine synthase/serine/threonine protein kinase compare
MMJJ_RS08625 -3.2 -1.8 magnesium/cobalt transporter CorA compare
MMJJ_RS04760 -3.1 -12.6 5,10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdC compare
MMJJ_RS05420 -3.1 -1.9 DNA-directed DNA polymerase II small subunit compare
MMJJ_RS05720 -3.1 -0.9 glutamine--fructose-6-phosphate transaminase (isomerizing) compare
MMJJ_RS08430 -3.1 -4.4 small nuclear ribonucleoprotein compare
MMJJ_RS08660 -3.0 -1.0 acetylornithine transaminase compare
MMJJ_RS07035 -3.0 -0.7 glycosyl transferase compare
MMJJ_RS05575 -3.0 -1.7 2-amino-5-formylamino-6-ribosylaminopyrimidin- 4(3H)-one 5'-monophosphate deformylase compare
MMJJ_RS05770 -3.0 -1.2 flagellar protein D compare
MMJJ_RS06660 -2.9 -5.4 DUF1188 domain-containing protein compare
MMJJ_RS03230 -2.9 -1.4 NAD(P)/FAD-dependent oxidoreductase compare
MMJJ_RS05280 -2.9 -0.4 hypothetical protein compare
MMJJ_RS05360 -2.8 -3.6 nickel-responsive transcriptional regulator NikR compare
MMJJ_RS07715 -2.8 -1.8 UbiD family decarboxylase compare
MMJJ_RS00035 -2.8 -13.3 CO dehydrogenase/acetyl-CoA synthase complex subunit alpha compare
MMJJ_RS04720 -2.8 -1.0 IMP dehydrogenase compare
MMJJ_RS00430 -2.8 -1.0 ribonuclease Z compare
MMJJ_RS04770 -2.8 -1.4 formate-dependent phosphoribosylglycinamide formyltransferase compare
MMJJ_RS06365 -2.8 -15.4 methyl coenzyme M reductase-arginine methyltransferase Mmp10 compare
MMJJ_RS00355 -2.8 -1.4 ribonuclease P protein component 4 compare
MMJJ_RS00055 -2.8 -7.3 CO dehydrogenase/acetyl-CoA synthase subunit delta compare
MMJJ_RS04750 -2.8 -6.2 5,10-methenyltetrahydromethanopterin hydrogenase compare
MMJJ_RS03065 -2.8 -10.1 CBS domain-containing protein compare
MMJJ_RS04800 -2.8 -2.2 2-phospho-L-lactate guanylyltransferase compare
MMJJ_RS00285 -2.7 -10.1 UPF0254 family protein compare
MMJJ_RS08335 -2.7 -0.6 ABC transporter ATP-binding protein compare
MMJJ_RS05535 -2.7 -7.7 hypothetical protein compare
MMJJ_RS00040 -2.7 -5.8 CO dehydrogenase/acetyl-CoA synthase complex subunit epsilon compare
MMJJ_RS04565 -2.7 -0.8 sirohydrochlorin nickelochelatase compare
MMJJ_RS00060 -2.7 -13.7 acetyl-CoA decarbonylase/synthase complex subunit gamma compare
MMJJ_RS03190 -2.6 -0.8 phosphopyruvate hydratase compare
MMJJ_RS06250 -2.6 -1.0 nicotinamide-nucleotide adenylyltransferase compare
MMJJ_RS04790 -2.6 -1.2 biotin--[acetyl-CoA-carboxylase] ligase compare
MMJJ_RS03875 -2.6 -1.4 CBS domain-containing protein compare
MMJJ_RS00050 -2.6 -6.5 AAA family ATPase compare
MMJJ_RS05065 -2.6 -1.8 (4-{4-[2-(gamma-L- glutamylamino)ethyl]phenoxymethyl}furan-2-yl)methanamine synthase compare
MMJJ_RS07945 -2.5 -0.7 4Fe-4S binding protein compare
MMJJ_RS00045 -2.5 -9.8 CO dehydrogenase/CO-methylating acetyl-CoA synthase complex subunit beta compare
MMJJ_RS04995 -2.5 -3.0 Tfx family DNA-binding protein compare
MMJJ_RS01875 -2.5 -3.4 global nitrogen regulator NrpR compare
MMJJ_RS06215 -2.5 -2.2 agmatinase compare
MMJJ_RS06155 -2.5 -1.8 phosphatidylglycerophosphatase A compare
MMJJ_RS03810 -2.5 -0.9 AIR synthase-related protein compare
MMJJ_RS02200 -2.5 -5.2 chorismate pyruvate-lyase family protein compare
MMJJ_RS09095 -2.5 -5.3 MMPL family transporter compare
MMJJ_RS00395 -2.5 -3.6 DUF473 domain-containing protein compare
MMJJ_RS08095 -2.5 -1.0 cobyric acid synthase CobQ compare
MMJJ_RS02035 -2.5 -3.8 4-hydroxy-tetrahydrodipicolinate synthase compare
MMJJ_RS09135 -2.5 -4.8 archaeosine biosynthesis radical SAM protein RaSEA compare
MMJJ_RS00215 -2.4 -0.9 CCA tRNA nucleotidyltransferase compare
MMJJ_RS06760 -2.4 -1.7 Ni-sirohydrochlorin a,c-diamide synthase compare
MMJJ_RS08585 -2.4 -5.6 M42 family metallopeptidase compare
MMJJ_RS00275 -2.4 -0.6 coenzyme F420-0:L-glutamate ligase compare
MMJJ_RS02045 -2.4 -1.1 molybdenum cofactor guanylyltransferase compare
MMJJ_RS01820 -2.4 -2.2 MJ1244 family protein compare
MMJJ_RS08080 -2.4 -6.2 TIGR00300 family protein compare
MMJJ_RS08870 -2.4 -0.5 2-isopropylmalate synthase compare
MMJJ_RS07720 -2.4 -0.5 UPF0058 family protein compare
MMJJ_RS01750 -2.4 -0.6 ferrous iron transport protein A compare
MMJJ_RS09130 -2.4 -0.5 NFYB/HAP3 family transcription factor subunit compare
MMJJ_RS05930 -2.4 -0.6 cell division protein SepF compare
MMJJ_RS06390 -2.4 -0.5 NADPH-dependent F420 reductase compare
MMJJ_RS05445 -2.4 -0.5 2-oxoacid:acceptor oxidoreductase subunit alpha compare
MMJJ_RS08020 -2.4 -5.8 nucleotidyltransferase domain-containing protein compare
MMJJ_RS07190 -2.4 -2.1 RtcB family protein compare
MMJJ_RS02935 -2.4 -1.3 DNA-directed RNA polymerase subunit E'' compare
MMJJ_RS06225 -2.4 -0.8 adenosylmethionine decarboxylase compare
MMJJ_RS05070 -2.3 -0.8 DNA primase catalytic subunit PriS compare
MMJJ_RS01830 -2.3 -1.7 tRNA(Ile)(2)-agmatinylcytidine synthase compare
MMJJ_RS00080 -2.3 -9.7 DUF166 domain-containing protein compare
MMJJ_RS05415 -2.3 -0.6 hypothetical protein compare
MMJJ_RS03185 -2.3 -0.9 alanine--tRNA ligase compare
MMJJ_RS04615 -2.3 -2.0 methanogenesis marker 3 protein compare
MMJJ_RS01960 -2.3 -3.6 glycosyltransferase family 2 protein compare
MMJJ_RS00785 -2.3 -1.4 hypothetical protein compare
MMJJ_RS08170 -2.3 -1.0 diaminopimelate decarboxylase compare
MMJJ_RS03635 -2.3 -1.2 methionine--tRNA ligase compare
MMJJ_RS07000 -2.3 -0.5 TrkH family potassium uptake protein compare
MMJJ_RS04685 -2.3 -3.5 carbamoyltransferase HypF compare
MMJJ_RS00475 -2.2 -1.1 bifunctional ornithine acetyltransferase/N-acetylglutamate synthase compare
MMJJ_RS03785 -2.2 -0.9 hypothetical protein compare
MMJJ_RS03660 -2.2 -0.7 DUF447 family protein compare
MMJJ_RS00075 -2.2 -6.6 AAA family ATPase compare
MMJJ_RS05935 -2.2 -0.7 Era-like GTP-binding protein compare
MMJJ_RS06915 -2.2 -7.0 helix-turn-helix domain-containing protein compare
MMJJ_RS00270 -2.2 -1.3 adenosylcobinamide-GDP ribazoletransferase compare
MMJJ_RS07245 -2.1 -2.1 amidohydrolase family protein compare
MMJJ_RS06150 -2.1 -2.1 DUF483 domain-containing protein compare
MMJJ_RS06695 -2.1 -1.1 amidohydrolase compare
MMJJ_RS08340 -2.1 -2.1 archaeoflavoprotein AfpA compare
MMJJ_RS05995 -2.1 -0.8 ATP-binding cassette domain-containing protein compare
MMJJ_RS03585 -2.1 -0.3 methanogenesis marker 6 protein compare
MMJJ_RS03710 -2.1 -3.9 DUF2111 domain-containing protein compare
MMJJ_RS03270 -2.1 -0.8 ribosome biogenesis/translation initiation ATPase RLI compare
MMJJ_RS06255 -2.1 -3.7 tRNA uridine(34) 5-carboxymethylaminomethyl modification radical SAM/GNAT enzyme Elp3 compare
MMJJ_RS08840 -2.1 -1.8 calcium/sodium antiporter compare
MMJJ_RS07955 -2.1 -6.3 ThiF family adenylyltransferase compare
MMJJ_RS05765 -2.1 -0.5 flagellar protein E compare
MMJJ_RS05490 -2.0 -0.6 imidazole glycerol phosphate synthase subunit HisF compare
MMJJ_RS06380 -2.0 -1.2 signal recognition particle protein Srp54 compare
MMJJ_RS03150 -2.0 -2.2 2-phospho-L-lactate transferase compare
MMJJ_RS03125 -2.0 -0.7 GMC oxidoreductase compare
MMJJ_RS09035 -2.0 -2.6 OB-fold nucleic acid binding domain-containing protein compare
MMJJ_RS02855 -2.0 -5.0 DEAD/DEAH box helicase compare
MMJJ_RS07410 -2.0 -1.5 methanogenesis marker protein Mmp4/MtxX compare
MMJJ_RS06625 -2.0 -0.4 pyruvate synthase subunit PorB compare
MMJJ_RS00580 -2.0 -0.5 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase subunit CofG compare
MMJJ_RS04180 -2.0 -1.2 metalloregulator ArsR/SmtB family transcription factor compare
MMJJ_RS05190 -2.0 -3.0 gamma carbonic anhydrase family protein compare
MMJJ_RS00125 -2.0 -1.0 KEOPS complex subunit Cgi121 compare
MMJJ_RS06910 -2.0 -0.7 energy-converting NiFe hydrogenase A subunit EhaA compare
MMJJ_RS05560 -2.0 -2.4 30S ribosomal protein S27e compare
MMJJ_RS04050 -1.9 -0.5 dihydroneopterin aldolase family protein compare
MMJJ_RS07005 -1.9 -2.6 transcription factor S compare
MMJJ_RS01935 -1.9 -0.7 O-phosphoseryl-tRNA(Sec) selenium transferase compare
MMJJ_RS01350 -1.9 -3.2 sodium:proton antiporter compare
MMJJ_RS03815 -1.9 -0.6 nascent polypeptide-associated complex protein compare
MMJJ_RS06175 -1.9 -0.6 DUF1743 domain-containing protein compare
MMJJ_RS04520 -1.9 -1.6 coenzyme F430 synthase compare
MMJJ_RS04200 -1.9 -2.1 triphosphoribosyl-dephospho-CoA synthase compare
MMJJ_RS06220 -1.9 -2.8 polyamine aminopropyltransferase compare
MMJJ_RS08795 -1.9 -1.0 phosphoglucosamine mutase compare
MMJJ_RS00600 -1.9 -1.1 hydroxymethylbilane synthase compare
MMJJ_RS03200 -1.9 -0.6 uroporphyrinogen-III synthase compare
MMJJ_RS00030 -1.9 -7.2 thymidylate synthase compare
MMJJ_RS08010 -1.9 -3.5 phosphoadenosine phosphosulfate reductase family protein compare
MMJJ_RS05610 -1.9 -1.5 CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol synthase compare
MMJJ_RS04730 -1.9 -0.8 tyrosine decarboxylase MfnA compare
MMJJ_RS02090 -1.9 -1.8 tyramine--L-glutamate ligase compare
MMJJ_RS07275 -1.9 -0.6 formate--phosphoribosylaminoimidazolecarboxamide ligase compare
MMJJ_RS07370 -1.9 -3.1 tRNA 4-thiouridine(8) synthase ThiI compare
MMJJ_RS01285 -1.8 -2.8 CopG family ribbon-helix-helix protein compare
MMJJ_RS07725 -1.8 -2.9 DNA primase DnaG compare
MMJJ_RS03820 -1.8 -0.7 hydrogenase formation protein HypD compare
MMJJ_RS08500 -1.8 -3.2 L-sulfolactate dehydrogenase compare
MMJJ_RS01690 -1.8 -0.6 methanogenesis marker 12 protein compare
MMJJ_RS07950 -1.8 -1.0 4Fe-4S binding protein compare
MMJJ_RS01360 -1.8 -0.5 UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing) compare
MMJJ_RS06485 -1.8 -0.9 phosphoglycerate kinase compare
MMJJ_RS07630 -1.8 -7.2 hypothetical protein compare
MMJJ_RS01200 -1.8 -0.8 PRC-barrel domain-containing protein compare
MMJJ_RS06755 -1.8 -6.0 diadenylate cyclase compare
MMJJ_RS06835 -1.8 -7.0 4Fe-4S binding protein compare
MMJJ_RS06855 -1.7 -0.3 DUF2104 domain-containing protein compare
MMJJ_RS09390 -1.7 -1.8 hypothetical protein compare
MMJJ_RS06030 -1.7 -2.1 4Fe-4S binding protein compare
MMJJ_RS07155 -1.7 -5.3 [5-(aminomethyl)furan-3-yl]methyl phosphate kinase compare
MMJJ_RS08950 -1.7 -3.3 DUF22 domain-containing protein compare
MMJJ_RS01940 -1.7 -4.9 hypothetical protein compare
MMJJ_RS03895 -1.7 -0.8 hydrogenase expression/formation protein HypE compare
MMJJ_RS04655 -1.7 -3.3 FAD-dependent oxidoreductase compare
MMJJ_RS08060 -1.7 -3.9 DNA repair and recombination protein RadA compare
MMJJ_RS01415 -1.7 -0.6 beta-CASP ribonuclease aCPSF1 compare
MMJJ_RS08320 -1.7 -0.9 CDP-diacylglycerol--serine O-phosphatidyltransferase compare
MMJJ_RS03160 -1.7 -6.1 winged helix-turn-helix transcriptional regulator compare
MMJJ_RS07360 -1.7 -0.6 TIGR00269 family protein compare
MMJJ_RS09030 -1.6 -7.3 hypothetical protein compare
MMJJ_RS00265 -1.6 -2.8 TIGR02253 family HAD-type hydrolase compare
MMJJ_RS03245 -1.6 -0.5 UMP kinase compare
MMJJ_RS09085 -1.6 -5.6 minichromosome maintenance protein MCM compare


Specific Phenotypes

None in this experiment

For Methanococcus maripaludis JJ in stress experiments

For stress Nitrofurantoin across organisms