Experiment set7S434 for Methanococcus maripaludis JJ

Compare to:

McCas_formate_complete Irgasan 0.0125 mM

200 most important genes:

  gene name fitness t score description  
MMJJ_RS00525 -5.8 -1.1 Dabb family protein compare
MMJJ_RS07505 -4.9 -0.5 DNA-directed RNA polymerase subunit K compare
MMJJ_RS05590 -4.5 -1.0 homoserine dehydrogenase compare
MMJJ_RS03490 -4.5 -1.0 ribonuclease VapC compare
MMJJ_RS07960 -4.4 -1.0 quinolinate synthase NadA compare
MMJJ_RS05065 -4.2 -1.3 (4-{4-[2-(gamma-L- glutamylamino)ethyl]phenoxymethyl}furan-2-yl)methanamine synthase compare
MMJJ_RS04970 -4.2 -0.9 DUF655 domain-containing protein compare
MMJJ_RS08810 -4.1 -0.4 DUF4040 domain-containing protein compare
MMJJ_RS05380 -4.1 -0.6 hypothetical protein compare
MMJJ_RS06340 -4.0 -1.5 coenzyme-B sulfoethylthiotransferase subunit alpha compare
MMJJ_RS07360 -4.0 -0.7 TIGR00269 family protein compare
MMJJ_RS00935 -3.9 -9.9 nickel pincer cofactor biosynthesis protein LarB compare
MMJJ_RS03270 -3.9 -0.8 ribosome biogenesis/translation initiation ATPase RLI compare
MMJJ_RS02040 -3.8 -1.0 Asp-tRNA(Asn) amidotransferase subunit GatC compare
MMJJ_RS00050 -3.7 -6.9 AAA family ATPase compare
MMJJ_RS04485 -3.7 -5.2 riboflavin synthase compare
MMJJ_RS00060 -3.7 -16.0 acetyl-CoA decarbonylase/synthase complex subunit gamma compare
MMJJ_RS01880 -3.6 -1.0 RlmE family RNA methyltransferase compare
MMJJ_RS00475 -3.6 -0.8 bifunctional ornithine acetyltransferase/N-acetylglutamate synthase compare
MMJJ_RS04720 -3.6 -0.8 IMP dehydrogenase compare
MMJJ_RS00045 -3.6 -11.7 CO dehydrogenase/CO-methylating acetyl-CoA synthase complex subunit beta compare
MMJJ_RS00055 -3.5 -6.5 CO dehydrogenase/acetyl-CoA synthase subunit delta compare
MMJJ_RS00065 -3.5 -7.8 4Fe-4S dicluster domain-containing protein compare
MMJJ_RS07955 -3.5 -9.4 ThiF family adenylyltransferase compare
MMJJ_RS08500 -3.5 -4.4 L-sulfolactate dehydrogenase compare
MMJJ_RS00075 -3.5 -8.4 AAA family ATPase compare
MMJJ_RS08535 -3.5 -1.5 NOL1/NOP2/sun family putative RNA methylase compare
MMJJ_RS04975 -3.4 -0.8 glycosyltransferase family 4 protein compare
MMJJ_RS03245 -3.4 -0.5 UMP kinase compare
MMJJ_RS05575 -3.4 -1.6 2-amino-5-formylamino-6-ribosylaminopyrimidin- 4(3H)-one 5'-monophosphate deformylase compare
MMJJ_RS04150 -3.4 -1.1 DUF5379 domain-containing protein compare
MMJJ_RS03920 -3.4 -12.2 nickel pincer cofactor biosynthesis protein LarC compare
MMJJ_RS06905 -3.3 -0.7 hypothetical protein compare
MMJJ_RS09035 -3.3 -3.4 OB-fold nucleic acid binding domain-containing protein compare
MMJJ_RS00450 -3.3 -0.7 DUF126 domain-containing protein compare
MMJJ_RS07975 -3.3 -6.8 ATP-dependent sacrificial sulfur transferase LarE compare
MMJJ_RS06600 -3.3 -0.8 DUF555 domain-containing protein compare
MMJJ_RS00035 -3.2 -11.5 CO dehydrogenase/acetyl-CoA synthase complex subunit alpha compare
MMJJ_RS01405 -3.2 -0.5 proline--tRNA ligase compare
MMJJ_RS03865 -3.2 -0.6 phosphoribosyl-AMP cyclohydrolase compare
MMJJ_RS04595 -3.1 -2.5 hypothetical protein compare
MMJJ_RS07190 -3.1 -1.2 RtcB family protein compare
MMJJ_RS03965 -3.0 -0.6 DNA-directed RNA polymerase subunit L compare
MMJJ_RS04750 -3.0 -6.0 5,10-methenyltetrahydromethanopterin hydrogenase compare
MMJJ_RS00040 -3.0 -6.3 CO dehydrogenase/acetyl-CoA synthase complex subunit epsilon compare
MMJJ_RS01810 -3.0 -0.8 methyl coenzyme M reductase system, component A2 compare
MMJJ_RS04870 -3.0 -0.9 tRNA-Asp compare
MMJJ_RS00285 -3.0 -11.7 UPF0254 family protein compare
MMJJ_RS00080 -3.0 -11.1 DUF166 domain-containing protein compare
MMJJ_RS03185 -3.0 -0.8 alanine--tRNA ligase compare
MMJJ_RS07950 -3.0 -0.8 4Fe-4S binding protein compare
MMJJ_RS00560 -2.9 -0.9 homoisocitrate dehydrogenase compare
MMJJ_RS05995 -2.9 -0.7 ATP-binding cassette domain-containing protein compare
MMJJ_RS01865 -2.9 -3.0 peptidyl-tRNA hydrolase Pth2 compare
MMJJ_RS03115 -2.9 -3.0 sulfopyruvate decarboxylase subunit alpha compare
MMJJ_RS04760 -2.9 -11.9 5,10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdC compare
MMJJ_RS08190 -2.8 -1.7 hypothetical protein compare
MMJJ_RS05280 -2.8 -0.4 hypothetical protein compare
MMJJ_RS06875 -2.8 -1.1 hypothetical protein compare
MMJJ_RS04200 -2.8 -1.2 triphosphoribosyl-dephospho-CoA synthase compare
MMJJ_RS05935 -2.7 -0.7 Era-like GTP-binding protein compare
MMJJ_RS08575 -2.7 -1.8 hypothetical protein compare
MMJJ_RS00215 -2.7 -0.7 CCA tRNA nucleotidyltransferase compare
MMJJ_RS06220 -2.7 -3.0 polyamine aminopropyltransferase compare
MMJJ_RS04050 -2.7 -0.5 dihydroneopterin aldolase family protein compare
MMJJ_RS08625 -2.7 -3.0 magnesium/cobalt transporter CorA compare
MMJJ_RS02045 -2.7 -1.0 molybdenum cofactor guanylyltransferase compare
MMJJ_RS04800 -2.7 -2.1 2-phospho-L-lactate guanylyltransferase compare
MMJJ_RS08010 -2.7 -5.1 phosphoadenosine phosphosulfate reductase family protein compare
MMJJ_RS08020 -2.6 -7.0 nucleotidyltransferase domain-containing protein compare
MMJJ_RS05195 -2.6 -3.0 hypothetical protein compare
MMJJ_RS05535 -2.6 -8.1 hypothetical protein compare
MMJJ_RS00270 -2.6 -1.1 adenosylcobinamide-GDP ribazoletransferase compare
MMJJ_RS08660 -2.6 -1.2 acetylornithine transaminase compare
MMJJ_RS02035 -2.6 -2.9 4-hydroxy-tetrahydrodipicolinate synthase compare
MMJJ_RS04755 -2.6 -7.0 5,10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdB compare
MMJJ_RS09175 -2.6 -0.5 anthranilate synthase component I compare
MMJJ_RS00570 -2.6 -0.7 ribonuclease P compare
MMJJ_RS00355 -2.6 -1.0 ribonuclease P protein component 4 compare
MMJJ_RS05070 -2.6 -0.6 DNA primase catalytic subunit PriS compare
MMJJ_RS06915 -2.6 -9.8 helix-turn-helix domain-containing protein compare
MMJJ_RS04730 -2.5 -0.7 tyrosine decarboxylase MfnA compare
MMJJ_RS03200 -2.5 -0.6 uroporphyrinogen-III synthase compare
MMJJ_RS00125 -2.5 -0.7 KEOPS complex subunit Cgi121 compare
MMJJ_RS00360 -2.5 -0.7 adenosylhomocysteinase compare
MMJJ_RS02200 -2.5 -4.3 chorismate pyruvate-lyase family protein compare
MMJJ_RS00070 -2.5 -1.6 CooT family nickel-binding protein compare
MMJJ_RS04565 -2.5 -0.7 sirohydrochlorin nickelochelatase compare
MMJJ_RS03225 -2.5 -1.1 4Fe-4S binding protein compare
MMJJ_RS06860 -2.5 -1.0 hypothetical protein compare
MMJJ_RS00205 -2.5 -1.7 adenosylcobinamide-phosphate synthase CbiB compare
MMJJ_RS04790 -2.4 -1.1 biotin--[acetyl-CoA-carboxylase] ligase compare
MMJJ_RS08080 -2.4 -6.1 TIGR00300 family protein compare
MMJJ_RS03615 -2.4 -0.7 cobalt-precorrin-8 methylmutase compare
MMJJ_RS03190 -2.4 -0.7 phosphopyruvate hydratase compare
MMJJ_RS07945 -2.4 -0.7 4Fe-4S binding protein compare
MMJJ_RS03785 -2.4 -0.7 hypothetical protein compare
MMJJ_RS01830 -2.4 -1.3 tRNA(Ile)(2)-agmatinylcytidine synthase compare
MMJJ_RS00210 -2.4 -0.8 DUF530 family protein compare
MMJJ_RS00430 -2.4 -0.8 ribonuclease Z compare
MMJJ_RS06660 -2.4 -4.8 DUF1188 domain-containing protein compare
MMJJ_RS03430 -2.4 -3.0 winged helix-turn-helix domain-containing protein compare
MMJJ_RS06695 -2.3 -0.9 amidohydrolase compare
MMJJ_RS06255 -2.3 -3.4 tRNA uridine(34) 5-carboxymethylaminomethyl modification radical SAM/GNAT enzyme Elp3 compare
MMJJ_RS03895 -2.3 -0.7 hydrogenase expression/formation protein HypE compare
MMJJ_RS07410 -2.3 -1.1 methanogenesis marker protein Mmp4/MtxX compare
MMJJ_RS07585 -2.3 -5.3 DHH family phosphoesterase compare
MMJJ_RS05770 -2.3 -1.0 flagellar protein D compare
MMJJ_RS01925 -2.3 -4.9 fibrillarin-like rRNA/tRNA 2'-O-methyltransferase compare
MMJJ_RS07720 -2.3 -0.5 UPF0058 family protein compare
MMJJ_RS02090 -2.2 -1.7 tyramine--L-glutamate ligase compare
MMJJ_RS06565 -2.2 -4.3 segregation/condensation protein A compare
MMJJ_RS06835 -2.2 -8.5 4Fe-4S binding protein compare
MMJJ_RS05360 -2.2 -3.1 nickel-responsive transcriptional regulator NikR compare
MMJJ_RS03875 -2.2 -1.2 CBS domain-containing protein compare
MMJJ_RS01785 -2.2 -0.6 50S ribosomal protein L14e compare
MMJJ_RS06910 -2.2 -0.6 energy-converting NiFe hydrogenase A subunit EhaA compare
MMJJ_RS05445 -2.2 -0.5 2-oxoacid:acceptor oxidoreductase subunit alpha compare
MMJJ_RS08430 -2.2 -2.9 small nuclear ribonucleoprotein compare
MMJJ_RS05190 -2.2 -3.7 gamma carbonic anhydrase family protein compare
MMJJ_RS04655 -2.2 -3.0 FAD-dependent oxidoreductase compare
MMJJ_RS00345 -2.2 -5.6 4-hydroxy-tetrahydrodipicolinate reductase compare
MMJJ_RS05930 -2.1 -0.5 cell division protein SepF compare
MMJJ_RS06180 -2.1 -1.2 tryptophan--tRNA ligase compare
MMJJ_RS05415 -2.1 -0.5 hypothetical protein compare
MMJJ_RS07035 -2.1 -0.9 glycosyl transferase compare
MMJJ_RS08795 -2.1 -1.0 phosphoglucosamine mutase compare
MMJJ_RS07370 -2.1 -2.9 tRNA 4-thiouridine(8) synthase ThiI compare
MMJJ_RS03150 -2.1 -1.7 2-phospho-L-lactate transferase compare
MMJJ_RS04700 -2.1 -2.4 deoxyhypusine synthase compare
MMJJ_RS08585 -2.1 -3.5 M42 family metallopeptidase compare
MMJJ_RS08095 -2.1 -1.4 cobyric acid synthase CobQ compare
MMJJ_RS08840 -2.1 -1.6 calcium/sodium antiporter compare
MMJJ_RS06260 -2.1 -3.3 6-carboxyhexanoate--CoA ligase compare
MMJJ_RS04965 -2.1 -1.7 RNA polymerase Rpb4 family protein compare
MMJJ_RS03110 -2.1 -1.2 tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))- methylthiotransferase compare
MMJJ_RS00550 -2.0 -4.5 AIR synthase-related protein compare
MMJJ_RS01590 -2.0 -0.9 adenine phosphoribosyltransferase compare
MMJJ_RS03230 -2.0 -1.6 NAD(P)/FAD-dependent oxidoreductase compare
MMJJ_RS09375 -2.0 -0.5 hypothetical protein compare
MMJJ_RS06725 -2.0 -6.6 MogA/MoaB family molybdenum cofactor biosynthesis protein compare
MMJJ_RS08340 -2.0 -2.3 archaeoflavoprotein AfpA compare
MMJJ_RS04475 -2.0 -1.5 3,4-dihydroxy-2-butanone-4-phosphate synthase compare
MMJJ_RS01355 -1.9 -1.3 UDP-N-acetyl-D-mannosamine dehydrogenase compare
MMJJ_RS08335 -1.9 -0.6 ABC transporter ATP-binding protein compare
MMJJ_RS08130 -1.9 -0.3 translation initiation factor IF-2 subunit gamma compare
MMJJ_RS00645 -1.9 -6.0 adenosylmethionine--8-amino-7-oxononanoate transaminase compare
MMJJ_RS07380 -1.9 -4.2 sulfide-dependent adenosine diphosphate thiazole synthase compare
MMJJ_RS01930 -1.9 -4.2 Pre-mRNA processing ribonucleoprotein compare
MMJJ_RS06250 -1.9 -0.9 nicotinamide-nucleotide adenylyltransferase compare
MMJJ_RS07155 -1.9 -5.3 [5-(aminomethyl)furan-3-yl]methyl phosphate kinase compare
MMJJ_RS05490 -1.9 -0.6 imidazole glycerol phosphate synthase subunit HisF compare
MMJJ_RS06930 -1.9 -0.8 type II methionyl aminopeptidase compare
MMJJ_RS01345 -1.8 -1.8 (5-formylfuran-3-yl)methyl phosphate synthase compare
MMJJ_RS05135 -1.8 -0.6 50S ribosomal protein L18Ae compare
MMJJ_RS01500 -1.8 -3.4 transcriptional regulator compare
MMJJ_RS07715 -1.8 -1.2 UbiD family decarboxylase compare
MMJJ_RS04875 -1.8 -0.4 tRNA-Lys compare
MMJJ_RS06270 -1.8 -4.2 dethiobiotin synthase compare
MMJJ_RS05720 -1.8 -1.0 glutamine--fructose-6-phosphate transaminase (isomerizing) compare
MMJJ_RS05155 -1.8 -2.1 5-amino-6-(D-ribitylamino)uracil--L-tyrosine 4-hydroxyphenyl transferase CofH compare
MMJJ_RS00370 -1.8 -0.8 asparagine synthase (glutamine-hydrolyzing) compare
MMJJ_RS07345 -1.8 -3.9 homocysteine biosynthesis protein compare
MMJJ_RS00275 -1.8 -0.6 coenzyme F420-0:L-glutamate ligase compare
MMJJ_RS06485 -1.8 -0.7 phosphoglycerate kinase compare
MMJJ_RS03170 -1.8 -3.3 DUF5612 domain-containing protein compare
MMJJ_RS07245 -1.7 -1.8 amidohydrolase family protein compare
MMJJ_RS03765 -1.7 -2.8 hypothetical protein compare
MMJJ_RS03095 -1.7 -0.9 bifunctional N(6)-L-threonylcarbamoyladenine synthase/serine/threonine protein kinase compare
MMJJ_RS02935 -1.7 -1.3 DNA-directed RNA polymerase subunit E'' compare
MMJJ_RS05170 -1.7 -4.7 Nif3-like dinuclear metal center hexameric protein compare
MMJJ_RS06375 -1.7 -1.4 UbiX family flavin prenyltransferase compare
MMJJ_RS03840 -1.7 -0.7 DHH family phosphoesterase compare
MMJJ_RS05655 -1.7 -3.7 HisA/HisF family protein compare
MMJJ_RS06175 -1.7 -0.6 DUF1743 domain-containing protein compare
MMJJ_RS06825 -1.7 -6.0 4Fe-4S binding protein compare
MMJJ_RS09295 -1.7 -0.3 hypothetical protein compare
MMJJ_RS02125 -1.7 -2.0 hypothetical protein compare
MMJJ_RS08345 -1.7 -5.8 flavodoxin family protein compare
MMJJ_RS06225 -1.7 -0.6 adenosylmethionine decarboxylase compare
MMJJ_RS06625 -1.7 -0.4 pyruvate synthase subunit PorB compare
MMJJ_RS00480 -1.7 -5.5 flippase compare
MMJJ_RS07705 -1.6 -0.7 GTP-binding protein EngB compare
MMJJ_RS01200 -1.6 -0.7 PRC-barrel domain-containing protein compare
MMJJ_RS00385 -1.6 -5.9 TIGR00454 family protein compare
MMJJ_RS06635 -1.6 -6.9 4Fe-4S binding protein compare
MMJJ_RS03820 -1.6 -0.6 hydrogenase formation protein HypD compare
MMJJ_RS08935 -1.6 -0.5 TIGR00288 family NYN domain-containing protein compare
MMJJ_RS05765 -1.6 -0.5 flagellar protein E compare
MMJJ_RS04995 -1.6 -2.1 Tfx family DNA-binding protein compare
MMJJ_RS05560 -1.6 -1.3 30S ribosomal protein S27e compare
MMJJ_RS01765 -1.6 -3.6 winged helix-turn-helix domain-containing protein compare
MMJJ_RS08320 -1.6 -0.8 CDP-diacylglycerol--serine O-phosphatidyltransferase compare
MMJJ_RS08490 -1.6 -1.6 rubrerythrin family protein compare
MMJJ_RS08025 -1.6 -2.0 hypothetical protein compare
MMJJ_RS01750 -1.6 -0.6 ferrous iron transport protein A compare
MMJJ_RS01350 -1.6 -2.9 sodium:proton antiporter compare
MMJJ_RS08155 -1.6 -1.0 cobalt-precorrin-5B (C(1))-methyltransferase CbiD compare
MMJJ_RS08330 -1.6 -0.5 SufD family Fe-S cluster assembly protein compare
MMJJ_RS00195 -1.5 -1.4 precorrin-3B C(17)-methyltransferase compare


Specific Phenotypes

None in this experiment

For Methanococcus maripaludis JJ in stress experiments

For stress Irgasan across organisms