Experiment set7S424 for Methanococcus maripaludis JJ

Compare to:

McCas_formate_complete Polymyxin B sulfate 0.05 mM

200 most important genes:

  gene name fitness t score description  
MMJJ_RS04485 -5.0 -6.9 riboflavin synthase compare
MMJJ_RS08575 -4.8 -2.4 hypothetical protein compare
MMJJ_RS04150 -4.8 -1.4 DUF5379 domain-containing protein compare
MMJJ_RS04970 -4.8 -1.3 DUF655 domain-containing protein compare
MMJJ_RS08810 -4.4 -0.6 DUF4040 domain-containing protein compare
MMJJ_RS00480 -4.3 -13.7 flippase compare
MMJJ_RS05380 -4.2 -0.8 hypothetical protein compare
MMJJ_RS00450 -4.2 -1.1 DUF126 domain-containing protein compare
MMJJ_RS03225 -4.1 -1.3 4Fe-4S binding protein compare
MMJJ_RS04790 -4.1 -1.6 biotin--[acetyl-CoA-carboxylase] ligase compare
MMJJ_RS03995 -4.0 -5.4 PHP domain-containing protein compare
MMJJ_RS05575 -4.0 -2.3 2-amino-5-formylamino-6-ribosylaminopyrimidin- 4(3H)-one 5'-monophosphate deformylase compare
MMJJ_RS06905 -3.9 -1.0 hypothetical protein compare
MMJJ_RS03865 -3.9 -0.9 phosphoribosyl-AMP cyclohydrolase compare
MMJJ_RS00210 -3.9 -1.1 DUF530 family protein compare
MMJJ_RS00040 -3.9 -8.2 CO dehydrogenase/acetyl-CoA synthase complex subunit epsilon compare
MMJJ_RS01830 -3.9 -1.5 tRNA(Ile)(2)-agmatinylcytidine synthase compare
MMJJ_RS08020 -3.9 -8.6 nucleotidyltransferase domain-containing protein compare
MMJJ_RS06875 -3.8 -1.1 hypothetical protein compare
MMJJ_RS05360 -3.8 -4.8 nickel-responsive transcriptional regulator NikR compare
MMJJ_RS06915 -3.8 -13.3 helix-turn-helix domain-containing protein compare
MMJJ_RS00055 -3.8 -8.7 CO dehydrogenase/acetyl-CoA synthase subunit delta compare
MMJJ_RS03155 -3.8 -10.5 hypothetical protein compare
MMJJ_RS09085 -3.7 -13.3 minichromosome maintenance protein MCM compare
MMJJ_RS04575 -3.7 -10.7 DUF116 domain-containing protein compare
MMJJ_RS07655 -3.7 -13.9 hypothetical protein compare
MMJJ_RS08660 -3.7 -1.5 acetylornithine transaminase compare
MMJJ_RS07350 -3.7 -1.4 4Fe-4S binding protein compare
MMJJ_RS05065 -3.7 -2.3 (4-{4-[2-(gamma-L- glutamylamino)ethyl]phenoxymethyl}furan-2-yl)methanamine synthase compare
MMJJ_RS00270 -3.7 -1.9 adenosylcobinamide-GDP ribazoletransferase compare
MMJJ_RS06930 -3.6 -1.2 type II methionyl aminopeptidase compare
MMJJ_RS09375 -3.6 -0.8 hypothetical protein compare
MMJJ_RS08320 -3.6 -1.1 CDP-diacylglycerol--serine O-phosphatidyltransferase compare
MMJJ_RS00475 -3.6 -1.6 bifunctional ornithine acetyltransferase/N-acetylglutamate synthase compare
MMJJ_RS00195 -3.6 -1.5 precorrin-3B C(17)-methyltransferase compare
MMJJ_RS08795 -3.6 -1.3 phosphoglucosamine mutase compare
MMJJ_RS08500 -3.5 -5.8 L-sulfolactate dehydrogenase compare
MMJJ_RS04200 -3.5 -1.9 triphosphoribosyl-dephospho-CoA synthase compare
MMJJ_RS00580 -3.5 -0.8 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase subunit CofG compare
MMJJ_RS00060 -3.5 -15.3 acetyl-CoA decarbonylase/synthase complex subunit gamma compare
MMJJ_RS01355 -3.5 -1.5 UDP-N-acetyl-D-mannosamine dehydrogenase compare
MMJJ_RS03230 -3.5 -2.0 NAD(P)/FAD-dependent oxidoreductase compare
MMJJ_RS03490 -3.5 -1.5 ribonuclease VapC compare
MMJJ_RS06725 -3.5 -9.5 MogA/MoaB family molybdenum cofactor biosynthesis protein compare
MMJJ_RS05535 -3.5 -10.8 hypothetical protein compare
MMJJ_RS00075 -3.5 -10.6 AAA family ATPase compare
MMJJ_RS02200 -3.5 -4.7 chorismate pyruvate-lyase family protein compare
MMJJ_RS08935 -3.4 -0.6 TIGR00288 family NYN domain-containing protein compare
MMJJ_RS04475 -3.4 -2.6 3,4-dihydroxy-2-butanone-4-phosphate synthase compare
MMJJ_RS00370 -3.4 -1.3 asparagine synthase (glutamine-hydrolyzing) compare
MMJJ_RS00045 -3.4 -12.7 CO dehydrogenase/CO-methylating acetyl-CoA synthase complex subunit beta compare
MMJJ_RS06940 -3.4 -9.1 metalloregulator ArsR/SmtB family transcription factor compare
MMJJ_RS08060 -3.4 -8.6 DNA repair and recombination protein RadA compare
MMJJ_RS08710 -3.3 -10.1 UTP--glucose-1-phosphate uridylyltransferase GalU compare
MMJJ_RS04975 -3.3 -1.4 glycosyltransferase family 4 protein compare
MMJJ_RS07410 -3.3 -1.4 methanogenesis marker protein Mmp4/MtxX compare
MMJJ_RS06225 -3.3 -1.0 adenosylmethionine decarboxylase compare
MMJJ_RS07590 -3.3 -12.3 flap endonuclease-1 compare
MMJJ_RS08535 -3.3 -2.3 NOL1/NOP2/sun family putative RNA methylase compare
MMJJ_RS00570 -3.3 -1.0 ribonuclease P compare
MMJJ_RS08840 -3.3 -2.6 calcium/sodium antiporter compare
MMJJ_RS06180 -3.3 -1.7 tryptophan--tRNA ligase compare
MMJJ_RS01810 -3.3 -1.2 methyl coenzyme M reductase system, component A2 compare
MMJJ_RS05070 -3.2 -1.0 DNA primase catalytic subunit PriS compare
MMJJ_RS08430 -3.2 -4.4 small nuclear ribonucleoprotein compare
MMJJ_RS03190 -3.2 -1.2 phosphopyruvate hydratase compare
MMJJ_RS03615 -3.2 -1.1 cobalt-precorrin-8 methylmutase compare
MMJJ_RS00035 -3.2 -14.7 CO dehydrogenase/acetyl-CoA synthase complex subunit alpha compare
MMJJ_RS00065 -3.2 -9.9 4Fe-4S dicluster domain-containing protein compare
MMJJ_RS07945 -3.1 -1.1 4Fe-4S binding protein compare
MMJJ_RS03205 -3.1 -7.1 metallophosphoesterase compare
MMJJ_RS00050 -3.1 -7.9 AAA family ATPase compare
MMJJ_RS01750 -3.1 -1.0 ferrous iron transport protein A compare
MMJJ_RS05720 -3.1 -1.5 glutamine--fructose-6-phosphate transaminase (isomerizing) compare
MMJJ_RS09130 -3.0 -0.8 NFYB/HAP3 family transcription factor subunit compare
MMJJ_RS06375 -3.0 -2.4 UbiX family flavin prenyltransferase compare
MMJJ_RS03815 -3.0 -0.8 nascent polypeptide-associated complex protein compare
MMJJ_RS08080 -3.0 -7.6 TIGR00300 family protein compare
MMJJ_RS00355 -3.0 -1.7 ribonuclease P protein component 4 compare
MMJJ_RS08625 -3.0 -5.3 magnesium/cobalt transporter CorA compare
MMJJ_RS07415 -3.0 -1.5 polyprenyl diphosphate synthase compare
MMJJ_RS01765 -3.0 -7.5 winged helix-turn-helix domain-containing protein compare
MMJJ_RS06175 -3.0 -0.9 DUF1743 domain-containing protein compare
MMJJ_RS06860 -3.0 -1.5 hypothetical protein compare
MMJJ_RS03810 -3.0 -1.3 AIR synthase-related protein compare
MMJJ_RS07245 -3.0 -2.7 amidohydrolase family protein compare
MMJJ_RS07670 -2.9 -13.2 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C-terminal domain compare
MMJJ_RS04760 -2.9 -12.4 5,10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdC compare
MMJJ_RS00125 -2.9 -1.4 KEOPS complex subunit Cgi121 compare
MMJJ_RS07345 -2.9 -5.8 homocysteine biosynthesis protein compare
MMJJ_RS02040 -2.9 -1.3 Asp-tRNA(Asn) amidotransferase subunit GatC compare
MMJJ_RS05710 -2.9 -3.1 single-stranded-DNA-specific exonuclease RecJ compare
MMJJ_RS07720 -2.9 -0.8 UPF0058 family protein compare
MMJJ_RS07470 -2.9 -0.8 50S ribosome-binding GTPase compare
MMJJ_RS00425 -2.9 -2.8 hypothetical protein compare
MMJJ_RS07960 -2.9 -1.8 quinolinate synthase NadA compare
MMJJ_RS03875 -2.9 -1.9 CBS domain-containing protein compare
MMJJ_RS09055 -2.9 -7.2 NFACT family protein compare
MMJJ_RS03060 -2.8 -1.0 methanogenesis marker 7 protein compare
MMJJ_RS09300 -2.8 -1.5 hypothetical protein compare
MMJJ_RS07155 -2.8 -7.1 [5-(aminomethyl)furan-3-yl]methyl phosphate kinase compare
MMJJ_RS07380 -2.8 -5.5 sulfide-dependent adenosine diphosphate thiazole synthase compare
MMJJ_RS01415 -2.8 -0.9 beta-CASP ribonuclease aCPSF1 compare
MMJJ_RS05995 -2.8 -1.1 ATP-binding cassette domain-containing protein compare
MMJJ_RS06910 -2.8 -0.9 energy-converting NiFe hydrogenase A subunit EhaA compare
MMJJ_RS07585 -2.8 -7.4 DHH family phosphoesterase compare
MMJJ_RS04700 -2.8 -3.0 deoxyhypusine synthase compare
MMJJ_RS09175 -2.8 -0.7 anthranilate synthase component I compare
MMJJ_RS07190 -2.8 -2.7 RtcB family protein compare
MMJJ_RS05415 -2.8 -0.8 hypothetical protein compare
MMJJ_RS06255 -2.8 -4.9 tRNA uridine(34) 5-carboxymethylaminomethyl modification radical SAM/GNAT enzyme Elp3 compare
MMJJ_RS01200 -2.8 -1.1 PRC-barrel domain-containing protein compare
MMJJ_RS05770 -2.8 -1.4 flagellar protein D compare
MMJJ_RS03115 -2.8 -4.2 sulfopyruvate decarboxylase subunit alpha compare
MMJJ_RS08005 -2.8 -11.8 formate dehydrogenase accessory sulfurtransferase FdhD compare
MMJJ_RS04995 -2.8 -4.0 Tfx family DNA-binding protein compare
MMJJ_RS03895 -2.7 -1.3 hydrogenase expression/formation protein HypE compare
MMJJ_RS03150 -2.7 -3.0 2-phospho-L-lactate transferase compare
MMJJ_RS03310 -2.7 -1.6 hypothetical protein compare
MMJJ_RS02935 -2.7 -1.9 DNA-directed RNA polymerase subunit E'' compare
MMJJ_RS06835 -2.7 -9.1 4Fe-4S binding protein compare
MMJJ_RS06250 -2.7 -1.3 nicotinamide-nucleotide adenylyltransferase compare
MMJJ_RS03930 -2.7 -9.4 hypothetical protein compare
MMJJ_RS02045 -2.7 -1.6 molybdenum cofactor guanylyltransferase compare
MMJJ_RS05610 -2.7 -1.9 CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol synthase compare
MMJJ_RS06390 -2.7 -0.7 NADPH-dependent F420 reductase compare
MMJJ_RS00415 -2.7 -7.1 DedA family protein compare
MMJJ_RS07665 -2.7 -15.9 formate dehydrogenase subunit alpha compare
MMJJ_RS03095 -2.7 -1.4 bifunctional N(6)-L-threonylcarbamoyladenine synthase/serine/threonine protein kinase compare
MMJJ_RS03920 -2.6 -12.7 nickel pincer cofactor biosynthesis protein LarC compare
MMJJ_RS01875 -2.6 -4.7 global nitrogen regulator NrpR compare
MMJJ_RS05765 -2.6 -0.7 flagellar protein E compare
MMJJ_RS03580 -2.6 -1.0 TIGR00303 family protein compare
MMJJ_RS00935 -2.6 -10.1 nickel pincer cofactor biosynthesis protein LarB compare
MMJJ_RS03125 -2.6 -1.1 GMC oxidoreductase compare
MMJJ_RS07280 -2.6 -6.5 phosphomannomutase/phosphoglucomutase compare
MMJJ_RS04800 -2.6 -3.5 2-phospho-L-lactate guanylyltransferase compare
MMJJ_RS04565 -2.6 -2.0 sirohydrochlorin nickelochelatase compare
MMJJ_RS08830 -2.6 -3.0 hypothetical protein compare
MMJJ_RS03785 -2.6 -1.3 hypothetical protein compare
MMJJ_RS02275 -2.6 -3.1 nucleotidyltransferase domain-containing protein compare
MMJJ_RS00215 -2.5 -1.4 CCA tRNA nucleotidyltransferase compare
MMJJ_RS01360 -2.5 -0.8 UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing) compare
MMJJ_RS04755 -2.5 -8.7 5,10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdB compare
MMJJ_RS04655 -2.5 -5.1 FAD-dependent oxidoreductase compare
MMJJ_RS06240 -2.5 -0.8 dihydropteroate synthase-like protein compare
MMJJ_RS03840 -2.5 -1.2 DHH family phosphoesterase compare
MMJJ_RS05155 -2.5 -3.4 5-amino-6-(D-ribitylamino)uracil--L-tyrosine 4-hydroxyphenyl transferase CofH compare
MMJJ_RS01865 -2.5 -2.9 peptidyl-tRNA hydrolase Pth2 compare
MMJJ_RS08825 -2.4 -4.7 hypothetical protein compare
MMJJ_RS02090 -2.4 -2.7 tyramine--L-glutamate ligase compare
MMJJ_RS06695 -2.4 -1.4 amidohydrolase compare
MMJJ_RS05935 -2.4 -1.0 Era-like GTP-binding protein compare
MMJJ_RS08010 -2.4 -5.6 phosphoadenosine phosphosulfate reductase family protein compare
MMJJ_RS00600 -2.4 -1.7 hydroxymethylbilane synthase compare
MMJJ_RS06700 -2.4 -2.7 L-seryl-tRNA(Sec) kinase compare
MMJJ_RS03820 -2.4 -1.1 hydrogenase formation protein HypD compare
MMJJ_RS04050 -2.4 -0.8 dihydroneopterin aldolase family protein compare
MMJJ_RS04730 -2.4 -1.2 tyrosine decarboxylase MfnA compare
MMJJ_RS04965 -2.4 -3.0 RNA polymerase Rpb4 family protein compare
MMJJ_RS06755 -2.4 -9.9 diadenylate cyclase compare
MMJJ_RS02035 -2.4 -4.7 4-hydroxy-tetrahydrodipicolinate synthase compare
MMJJ_RS07975 -2.4 -6.2 ATP-dependent sacrificial sulfur transferase LarE compare
MMJJ_RS07005 -2.3 -2.5 transcription factor S compare
MMJJ_RS05780 -2.3 -1.7 flagellin compare
MMJJ_RS08715 -2.3 -5.8 NAD-dependent epimerase/dehydratase family protein compare
MMJJ_RS04615 -2.3 -2.9 methanogenesis marker 3 protein compare
MMJJ_RS06485 -2.3 -1.2 phosphoglycerate kinase compare
MMJJ_RS08330 -2.3 -0.9 SufD family Fe-S cluster assembly protein compare
MMJJ_RS07275 -2.3 -0.9 formate--phosphoribosylaminoimidazolecarboxamide ligase compare
MMJJ_RS06660 -2.3 -5.6 DUF1188 domain-containing protein compare
MMJJ_RS06380 -2.3 -1.7 signal recognition particle protein Srp54 compare
MMJJ_RS08490 -2.3 -2.3 rubrerythrin family protein compare
MMJJ_RS07950 -2.3 -1.5 4Fe-4S binding protein compare
MMJJ_RS06625 -2.3 -0.6 pyruvate synthase subunit PorB compare
MMJJ_RS07970 -2.3 -1.2 O-phospho-L-seryl-tRNA:Cys-tRNA synthase compare
MMJJ_RS07485 -2.2 -3.8 DedA family protein compare
MMJJ_RS05190 -2.2 -4.2 gamma carbonic anhydrase family protein compare
MMJJ_RS01600 -2.2 -0.8 radical SAM protein compare
MMJJ_RS04505 -2.2 -5.0 CDC48 family AAA ATPase compare
MMJJ_RS03620 -2.2 -2.3 DUF2097 domain-containing protein compare
MMJJ_RS01870 -2.2 -0.6 methanogenesis marker 15 protein compare
MMJJ_RS03110 -2.2 -2.0 tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))- methylthiotransferase compare
MMJJ_RS01935 -2.2 -1.3 O-phosphoseryl-tRNA(Sec) selenium transferase compare
MMJJ_RS06855 -2.2 -0.5 DUF2104 domain-containing protein compare
MMJJ_RS00080 -2.2 -8.6 DUF166 domain-containing protein compare
MMJJ_RS00645 -2.1 -8.3 adenosylmethionine--8-amino-7-oxononanoate transaminase compare
MMJJ_RS04685 -2.1 -4.8 carbamoyltransferase HypF compare
MMJJ_RS06750 -2.1 -0.9 homoaconitase large subunit compare
MMJJ_RS05445 -2.1 -0.8 2-oxoacid:acceptor oxidoreductase subunit alpha compare
MMJJ_RS07680 -2.1 -6.7 glucose-6-phosphate isomerase compare
MMJJ_RS01690 -2.1 -1.2 methanogenesis marker 12 protein compare
MMJJ_RS06155 -2.1 -2.9 phosphatidylglycerophosphatase A compare
MMJJ_RS06805 -2.1 -1.1 monovalent cation/H+ antiporter subunit E compare
MMJJ_RS08035 -2.1 -4.2 cobalt-precorrin-7 (C(5))-methyltransferase compare
MMJJ_RS07955 -2.1 -6.8 ThiF family adenylyltransferase compare
MMJJ_RS04155 -2.1 -2.7 hypothetical protein compare
MMJJ_RS04750 -2.0 -5.0 5,10-methenyltetrahydromethanopterin hydrogenase compare
MMJJ_RS00275 -2.0 -0.8 coenzyme F420-0:L-glutamate ligase compare
MMJJ_RS05810 -2.0 -3.4 precorrin-4 C(11)-methyltransferase compare


Specific Phenotypes

For 4 genes in this experiment

For stress Polymyxin B sulfate in Methanococcus maripaludis JJ

For stress Polymyxin B sulfate across organisms