Experiment set7S411 for Methanococcus maripaludis JJ

Compare to:

McCas_formate_complete Spiramycin 0.1 mM

200 most important genes:

  gene name fitness t score description  
MMJJ_RS01865 -5.3 -4.6 peptidyl-tRNA hydrolase Pth2 compare
MMJJ_RS04875 -5.0 -0.8 tRNA-Lys compare
MMJJ_RS04970 -4.8 -1.4 DUF655 domain-containing protein compare
MMJJ_RS03270 -4.6 -1.4 ribosome biogenesis/translation initiation ATPase RLI compare
MMJJ_RS04485 -4.5 -7.3 riboflavin synthase compare
MMJJ_RS07960 -4.5 -2.1 quinolinate synthase NadA compare
MMJJ_RS00475 -4.4 -1.3 bifunctional ornithine acetyltransferase/N-acetylglutamate synthase compare
MMJJ_RS00450 -4.2 -1.2 DUF126 domain-containing protein compare
MMJJ_RS05590 -4.1 -1.7 homoserine dehydrogenase compare
MMJJ_RS00370 -4.1 -1.2 asparagine synthase (glutamine-hydrolyzing) compare
MMJJ_RS06905 -4.0 -1.2 hypothetical protein compare
MMJJ_RS03295 -4.0 -11.7 PHP domain-containing protein compare
MMJJ_RS03865 -3.9 -1.0 phosphoribosyl-AMP cyclohydrolase compare
MMJJ_RS07430 -3.9 -2.4 ribonuclease VapC compare
MMJJ_RS00210 -3.9 -1.3 DUF530 family protein compare
MMJJ_RS08535 -3.8 -2.7 NOL1/NOP2/sun family putative RNA methylase compare
MMJJ_RS01810 -3.8 -1.4 methyl coenzyme M reductase system, component A2 compare
MMJJ_RS07950 -3.7 -1.5 4Fe-4S binding protein compare
MMJJ_RS00040 -3.7 -8.2 CO dehydrogenase/acetyl-CoA synthase complex subunit epsilon compare
MMJJ_RS03095 -3.7 -1.4 bifunctional N(6)-L-threonylcarbamoyladenine synthase/serine/threonine protein kinase compare
MMJJ_RS06930 -3.7 -1.4 type II methionyl aminopeptidase compare
MMJJ_RS09375 -3.7 -1.0 hypothetical protein compare
MMJJ_RS04995 -3.7 -4.1 Tfx family DNA-binding protein compare
MMJJ_RS00270 -3.6 -2.1 adenosylcobinamide-GDP ribazoletransferase compare
MMJJ_RS05720 -3.6 -1.4 glutamine--fructose-6-phosphate transaminase (isomerizing) compare
MMJJ_RS00215 -3.6 -1.3 CCA tRNA nucleotidyltransferase compare
MMJJ_RS07380 -3.6 -7.4 sulfide-dependent adenosine diphosphate thiazole synthase compare
MMJJ_RS00050 -3.5 -8.9 AAA family ATPase compare
MMJJ_RS06250 -3.5 -1.4 nicotinamide-nucleotide adenylyltransferase compare
MMJJ_RS07035 -3.5 -1.2 glycosyl transferase compare
MMJJ_RS08135 -3.5 -4.5 30S ribosomal protein S6e compare
MMJJ_RS04050 -3.4 -0.9 dihydroneopterin aldolase family protein compare
MMJJ_RS02935 -3.4 -1.9 DNA-directed RNA polymerase subunit E'' compare
MMJJ_RS06225 -3.4 -1.2 adenosylmethionine decarboxylase compare
MMJJ_RS05575 -3.4 -2.6 2-amino-5-formylamino-6-ribosylaminopyrimidin- 4(3H)-one 5'-monophosphate deformylase compare
MMJJ_RS06600 -3.4 -1.6 DUF555 domain-containing protein compare
MMJJ_RS06180 -3.4 -2.2 tryptophan--tRNA ligase compare
MMJJ_RS00125 -3.4 -1.3 KEOPS complex subunit Cgi121 compare
MMJJ_RS08625 -3.3 -5.1 magnesium/cobalt transporter CorA compare
MMJJ_RS02045 -3.3 -1.7 molybdenum cofactor guanylyltransferase compare
MMJJ_RS03200 -3.3 -1.1 uroporphyrinogen-III synthase compare
MMJJ_RS00060 -3.3 -15.0 acetyl-CoA decarbonylase/synthase complex subunit gamma compare
MMJJ_RS05070 -3.2 -1.1 DNA primase catalytic subunit PriS compare
MMJJ_RS03230 -3.2 -2.6 NAD(P)/FAD-dependent oxidoreductase compare
MMJJ_RS08020 -3.2 -8.6 nucleotidyltransferase domain-containing protein compare
MMJJ_RS00570 -3.2 -1.1 ribonuclease P compare
MMJJ_RS06220 -3.2 -4.3 polyamine aminopropyltransferase compare
MMJJ_RS00600 -3.2 -1.6 hydroxymethylbilane synthase compare
MMJJ_RS03785 -3.2 -1.3 hypothetical protein compare
MMJJ_RS08620 -3.2 -3.0 DUF373 family protein compare
MMJJ_RS06725 -3.2 -10.2 MogA/MoaB family molybdenum cofactor biosynthesis protein compare
MMJJ_RS08500 -3.2 -5.3 L-sulfolactate dehydrogenase compare
MMJJ_RS05155 -3.2 -4.1 5-amino-6-(D-ribitylamino)uracil--L-tyrosine 4-hydroxyphenyl transferase CofH compare
MMJJ_RS03190 -3.2 -1.4 phosphopyruvate hydratase compare
MMJJ_RS08795 -3.2 -1.8 phosphoglucosamine mutase compare
MMJJ_RS06875 -3.2 -1.4 hypothetical protein compare
MMJJ_RS00045 -3.2 -14.8 CO dehydrogenase/CO-methylating acetyl-CoA synthase complex subunit beta compare
MMJJ_RS00035 -3.1 -15.5 CO dehydrogenase/acetyl-CoA synthase complex subunit alpha compare
MMJJ_RS05420 -3.1 -3.1 DNA-directed DNA polymerase II small subunit compare
MMJJ_RS09120 -3.1 -1.4 aspartate kinase compare
MMJJ_RS09130 -3.1 -0.9 NFYB/HAP3 family transcription factor subunit compare
MMJJ_RS06915 -3.1 -11.9 helix-turn-helix domain-containing protein compare
MMJJ_RS05535 -3.1 -11.2 hypothetical protein compare
MMJJ_RS05360 -3.1 -4.6 nickel-responsive transcriptional regulator NikR compare
MMJJ_RS06860 -3.1 -1.8 hypothetical protein compare
MMJJ_RS00055 -3.1 -8.0 CO dehydrogenase/acetyl-CoA synthase subunit delta compare
MMJJ_RS03055 -3.0 -1.4 hypothetical protein compare
MMJJ_RS07410 -3.0 -2.0 methanogenesis marker protein Mmp4/MtxX compare
MMJJ_RS07715 -3.0 -2.7 UbiD family decarboxylase compare
MMJJ_RS04200 -3.0 -3.1 triphosphoribosyl-dephospho-CoA synthase compare
MMJJ_RS05225 -3.0 -0.6 Gar1/Naf1 family protein compare
MMJJ_RS04800 -3.0 -3.5 2-phospho-L-lactate guanylyltransferase compare
MMJJ_RS09035 -3.0 -5.0 OB-fold nucleic acid binding domain-containing protein compare
MMJJ_RS02055 -3.0 -9.3 GTP 3',8-cyclase MoaA compare
MMJJ_RS06255 -3.0 -5.6 tRNA uridine(34) 5-carboxymethylaminomethyl modification radical SAM/GNAT enzyme Elp3 compare
MMJJ_RS07470 -3.0 -0.9 50S ribosome-binding GTPase compare
MMJJ_RS08320 -2.9 -1.7 CDP-diacylglycerol--serine O-phosphatidyltransferase compare
MMJJ_RS03875 -2.9 -2.2 CBS domain-containing protein compare
MMJJ_RS05595 -2.9 -2.0 hypothetical protein compare
MMJJ_RS06835 -2.9 -10.1 4Fe-4S binding protein compare
MMJJ_RS06760 -2.9 -2.3 Ni-sirohydrochlorin a,c-diamide synthase compare
MMJJ_RS04975 -2.8 -1.5 glycosyltransferase family 4 protein compare
MMJJ_RS06390 -2.8 -0.9 NADPH-dependent F420 reductase compare
MMJJ_RS05415 -2.8 -0.9 hypothetical protein compare
MMJJ_RS01350 -2.8 -5.7 sodium:proton antiporter compare
MMJJ_RS02090 -2.8 -3.0 tyramine--L-glutamate ligase compare
MMJJ_RS07505 -2.8 -0.7 DNA-directed RNA polymerase subunit K compare
MMJJ_RS03245 -2.8 -0.8 UMP kinase compare
MMJJ_RS08035 -2.8 -6.2 cobalt-precorrin-7 (C(5))-methyltransferase compare
MMJJ_RS07000 -2.8 -0.8 TrkH family potassium uptake protein compare
MMJJ_RS07190 -2.8 -3.1 RtcB family protein compare
MMJJ_RS03170 -2.8 -5.8 DUF5612 domain-containing protein compare
MMJJ_RS02200 -2.8 -7.1 chorismate pyruvate-lyase family protein compare
MMJJ_RS06695 -2.8 -1.7 amidohydrolase compare
MMJJ_RS06755 -2.7 -11.3 diadenylate cyclase compare
MMJJ_RS09175 -2.7 -0.8 anthranilate synthase component I compare
MMJJ_RS07245 -2.7 -3.4 amidohydrolase family protein compare
MMJJ_RS07785 -2.7 -1.1 fumarate reductase subunit A compare
MMJJ_RS07665 -2.7 -16.0 formate dehydrogenase subunit alpha compare
MMJJ_RS09085 -2.7 -11.2 minichromosome maintenance protein MCM compare
MMJJ_RS07995 -2.7 -4.3 molybdenum cofactor biosynthesis protein MoaE compare
MMJJ_RS04790 -2.6 -2.2 biotin--[acetyl-CoA-carboxylase] ligase compare
MMJJ_RS08080 -2.6 -6.7 TIGR00300 family protein compare
MMJJ_RS00275 -2.6 -1.2 coenzyme F420-0:L-glutamate ligase compare
MMJJ_RS04475 -2.6 -2.3 3,4-dihydroxy-2-butanone-4-phosphate synthase compare
MMJJ_RS03615 -2.6 -1.4 cobalt-precorrin-8 methylmutase compare
MMJJ_RS03670 -2.6 -1.4 precorrin-2 C(20)-methyltransferase compare
MMJJ_RS08005 -2.6 -12.2 formate dehydrogenase accessory sulfurtransferase FdhD compare
MMJJ_RS08000 -2.6 -6.8 HesA/MoeB/ThiF family protein compare
MMJJ_RS02920 -2.5 -1.1 30S ribosomal protein S27ae compare
MMJJ_RS00080 -2.5 -10.4 DUF166 domain-containing protein compare
MMJJ_RS08855 -2.5 -2.9 cyclic pyranopterin monophosphate synthase MoaC compare
MMJJ_RS04760 -2.5 -13.2 5,10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdC compare
MMJJ_RS05560 -2.5 -3.1 30S ribosomal protein S27e compare
MMJJ_RS03840 -2.5 -1.4 DHH family phosphoesterase compare
MMJJ_RS02275 -2.5 -3.3 nucleotidyltransferase domain-containing protein compare
MMJJ_RS03765 -2.5 -5.0 hypothetical protein compare
MMJJ_RS07670 -2.5 -12.5 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C-terminal domain compare
MMJJ_RS03125 -2.5 -1.7 GMC oxidoreductase compare
MMJJ_RS00075 -2.5 -9.0 AAA family ATPase compare
MMJJ_RS05380 -2.4 -1.0 hypothetical protein compare
MMJJ_RS00205 -2.4 -3.6 adenosylcobinamide-phosphate synthase CbiB compare
MMJJ_RS02035 -2.4 -3.6 4-hydroxy-tetrahydrodipicolinate synthase compare
MMJJ_RS04145 -2.4 -6.9 glutamate-1-semialdehyde 2,1-aminomutase compare
MMJJ_RS03810 -2.4 -1.9 AIR synthase-related protein compare
MMJJ_RS05190 -2.4 -4.4 gamma carbonic anhydrase family protein compare
MMJJ_RS03150 -2.4 -3.7 2-phospho-L-lactate transferase compare
MMJJ_RS00065 -2.4 -6.7 4Fe-4S dicluster domain-containing protein compare
MMJJ_RS08330 -2.4 -1.0 SufD family Fe-S cluster assembly protein compare
MMJJ_RS05135 -2.3 -0.9 50S ribosomal protein L18Ae compare
MMJJ_RS04650 -2.3 -3.8 nitrogenase iron protein compare
MMJJ_RS04150 -2.3 -1.5 DUF5379 domain-containing protein compare
MMJJ_RS06910 -2.3 -1.5 energy-converting NiFe hydrogenase A subunit EhaA compare
MMJJ_RS03110 -2.3 -2.1 tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))- methylthiotransferase compare
MMJJ_RS00285 -2.3 -10.7 UPF0254 family protein compare
MMJJ_RS08010 -2.3 -5.0 phosphoadenosine phosphosulfate reductase family protein compare
MMJJ_RS01355 -2.3 -2.1 UDP-N-acetyl-D-mannosamine dehydrogenase compare
MMJJ_RS07720 -2.3 -1.0 UPF0058 family protein compare
MMJJ_RS05260 -2.3 -2.5 ATP-grasp domain-containing protein compare
MMJJ_RS08430 -2.3 -4.4 small nuclear ribonucleoprotein compare
MMJJ_RS00355 -2.3 -2.3 ribonuclease P protein component 4 compare
MMJJ_RS00550 -2.3 -5.5 AIR synthase-related protein compare
MMJJ_RS05835 -2.3 -13.6 bis-aminopropyl spermidine synthase family protein conserved
MMJJ_RS03160 -2.3 -11.4 winged helix-turn-helix transcriptional regulator compare
MMJJ_RS06215 -2.2 -3.3 agmatinase compare
MMJJ_RS01935 -2.2 -1.5 O-phosphoseryl-tRNA(Sec) selenium transferase compare
MMJJ_RS00195 -2.2 -2.3 precorrin-3B C(17)-methyltransferase compare
MMJJ_RS04010 -2.2 -4.4 archaeal proteasome endopeptidase complex subunit alpha compare
MMJJ_RS07955 -2.2 -8.5 ThiF family adenylyltransferase compare
MMJJ_RS09190 -2.2 -0.8 tryptophan synthase subunit beta compare
MMJJ_RS06040 -2.2 -1.4 NADH-quinone oxidoreductase subunit H compare
MMJJ_RS01875 -2.2 -5.0 global nitrogen regulator NrpR compare
MMJJ_RS01600 -2.2 -0.9 radical SAM protein compare
MMJJ_RS09055 -2.2 -7.6 NFACT family protein compare
MMJJ_RS08155 -2.2 -2.1 cobalt-precorrin-5B (C(1))-methyltransferase CbiD compare
MMJJ_RS04700 -2.2 -3.6 deoxyhypusine synthase compare
MMJJ_RS04750 -2.2 -8.9 5,10-methenyltetrahydromethanopterin hydrogenase compare
MMJJ_RS04155 -2.2 -2.6 hypothetical protein compare
MMJJ_RS01870 -2.2 -0.7 methanogenesis marker 15 protein compare
MMJJ_RS06700 -2.1 -3.1 L-seryl-tRNA(Sec) kinase compare
MMJJ_RS03620 -2.1 -2.1 DUF2097 domain-containing protein compare
MMJJ_RS01410 -2.1 -4.9 archaeal proteasome endopeptidase complex subunit beta compare
MMJJ_RS08060 -2.1 -5.8 DNA repair and recombination protein RadA compare
MMJJ_RS07945 -2.1 -1.4 4Fe-4S binding protein compare
MMJJ_RS04640 -2.1 -12.3 TIGR01177 family methyltransferase compare
MMJJ_RS02855 -2.1 -6.2 DEAD/DEAH box helicase compare
MMJJ_RS05810 -2.1 -4.1 precorrin-4 C(11)-methyltransferase compare
MMJJ_RS07155 -2.1 -6.6 [5-(aminomethyl)furan-3-yl]methyl phosphate kinase compare
MMJJ_RS06240 -2.1 -1.0 dihydropteroate synthase-like protein compare
MMJJ_RS07275 -2.1 -1.3 formate--phosphoribosylaminoimidazolecarboxamide ligase compare
MMJJ_RS05995 -2.1 -1.3 ATP-binding cassette domain-containing protein compare
MMJJ_RS01360 -2.1 -1.0 UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing) compare
MMJJ_RS04755 -2.0 -8.4 5,10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdB compare
MMJJ_RS05655 -2.0 -4.7 HisA/HisF family protein compare
MMJJ_RS01820 -2.0 -2.6 MJ1244 family protein compare
MMJJ_RS00560 -2.0 -1.8 homoisocitrate dehydrogenase compare
MMJJ_RS03965 -2.0 -1.0 DNA-directed RNA polymerase subunit L compare
MMJJ_RS01415 -2.0 -1.2 beta-CASP ribonuclease aCPSF1 compare
MMJJ_RS03225 -2.0 -2.1 4Fe-4S binding protein compare
MMJJ_RS05440 -2.0 -9.5 serine/threonine protein kinase compare
MMJJ_RS05280 -2.0 -0.6 hypothetical protein compare
MMJJ_RS04985 -2.0 -1.5 glutamyl-tRNA reductase compare
MMJJ_RS06375 -1.9 -2.1 UbiX family flavin prenyltransferase compare
MMJJ_RS05445 -1.9 -0.8 2-oxoacid:acceptor oxidoreductase subunit alpha compare
MMJJ_RS03185 -1.9 -1.2 alanine--tRNA ligase compare
MMJJ_RS03655 -1.9 -3.0 replication factor C large subunit compare
MMJJ_RS07725 -1.9 -3.7 DNA primase DnaG compare
MMJJ_RS03995 -1.9 -4.1 PHP domain-containing protein compare
MMJJ_RS07350 -1.9 -1.8 4Fe-4S binding protein compare
MMJJ_RS06660 -1.9 -4.9 DUF1188 domain-containing protein compare
MMJJ_RS01750 -1.9 -1.1 ferrous iron transport protein A compare
MMJJ_RS08840 -1.8 -2.6 calcium/sodium antiporter compare
MMJJ_RS00425 -1.8 -2.5 hypothetical protein compare
MMJJ_RS07980 -1.8 -7.2 biotin synthase BioB compare
MMJJ_RS07975 -1.8 -6.3 ATP-dependent sacrificial sulfur transferase LarE compare
MMJJ_RS04615 -1.8 -3.0 methanogenesis marker 3 protein compare
MMJJ_RS03820 -1.8 -1.6 hydrogenase formation protein HypD compare
MMJJ_RS04525 -1.8 -2.1 hypothetical protein compare
MMJJ_RS07875 -1.8 -1.2 FAD-dependent oxidoreductase compare
MMJJ_RS07840 -1.8 -2.0 Glu-tRNA(Gln) amidotransferase subunit GatD compare


Specific Phenotypes

For 4 genes in this experiment

For stress Spiramycin in Methanococcus maripaludis JJ

For stress Spiramycin across organisms