Experiment set7IT093 for Rhodospirillum rubrum S1H

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Succinate carbon source

200 most important genes:

  gene name fitness t score description  
Rru_A1897 -5.7 -9.6 Indole-3-glycerol-phosphate synthase (NCBI) compare
Rru_A3594 -5.7 -6.8 Histidine biosynthesis protein HisF (NCBI) compare
Rru_A3751 -5.6 -15.4 Argininosuccinate synthase (NCBI) compare
Rru_A1189 -5.6 -17.4 3-isopropylmalate dehydratase large subunit region (NCBI) compare
Rru_A3162 -5.5 -19.8 Prephenate dehydratase (NCBI) compare
Rru_A0394 -5.3 -6.3 Amino-acid N-acetyltransferase (NCBI) compare
Rru_A1928 -5.3 -17.4 Yeast 2-isopropylmalate synthase (NCBI) compare
Rru_A3267 -5.3 -12.5 Methionine biosynthesis MetW (NCBI) compare
Rru_A2885 -5.2 -22.2 Carbamoyl-phosphate synthase, small subunit (NCBI) compare
Rru_A3428 -5.2 -14.7 Tryptophan synthase (NCBI) compare
Rru_A2886 -5.2 -25.6 Carbamoyl-phosphate synthase, large subunit, glutamine-dependent (NCBI) compare
Rru_A0468 -5.1 -7.2 Acetolactate synthase, small subunit (NCBI) compare
Rru_A0467 -4.9 -15.3 Acetolactate synthase, large subunit, biosynthetic type (NCBI) compare
Rru_A3266 -4.9 -14.7 Homoserine O-acetyltransferase (NCBI) compare
Rru_A3277 -4.8 -9.5 Acetylornithine and succinylornithine aminotransferase (NCBI) compare
Rru_A1191 -4.8 -11.5 3-isopropylmalate dehydrogenase (NCBI) compare
Rru_A3425 -4.8 -6.5 Phosphoribosylanthranilate isomerase (NCBI) compare
Rru_A1530 -4.7 -23.0 5,10-methylenetetrahydrofolate reductase (NCBI) compare
Rru_A1786 -4.6 -24.6 Dihydroxy-acid dehydratase (NCBI) compare
Rru_A1105 -4.6 -7.8 tRNA synthetase, class II (G, H, P and S) (NCBI) compare
Rru_A2421 -4.5 -8.8 N-acetyl-gamma-glutamyl-phosphate reductase (NCBI) compare
Rru_A2772 -4.5 -5.3 ATP phosphoribosyltransferase (NCBI) compare
Rru_A0469 -4.4 -17.2 Ketol-acid reductoisomerase (NCBI) compare
Rru_A3165 -4.4 -7.3 Histidinol-phosphate phosphatase, putative, inositol monophosphatase (NCBI) compare
Rru_A3424 -4.4 -6.7 Orotidine-5'-phosphate decarboxylase (NCBI) compare
Rru_A1896 -4.4 -11.9 Anthranilate phosphoribosyl transferase (NCBI) compare
Rru_A1190 -4.3 -2.7 3-isopropylmalate dehydratase small subunit region (NCBI) compare
Rru_A1239 -4.2 -5.9 Glutamate 5-kinase, ProB-related (NCBI) compare
Rru_A2549 -4.2 -9.0 HAD-superfamily hydrolase subfamily IIB (NCBI) compare
Rru_A3264 -4.1 -11.1 Histidinol-phosphate aminotransferase (NCBI) compare
Rru_A0514 -4.0 -11.1 Dihydroorotate dehydrogenase 2 (NCBI) compare
Rru_A3214 -3.9 -16.6 O-succinylhomoserine sulfhydrylase (NCBI) compare
Rru_A3190 -3.7 -2.5 Aspartate carbamoyltransferase (NCBI) compare
Rru_A3276 -3.7 -3.1 Ornithine carbamoyltransferase (NCBI) compare
Rru_A1895 -3.7 -2.2 Glutamine amidotransferase of anthranilate synthase (NCBI) compare
Rru_A3191 -3.6 -15.3 Dihydroorotase multifunctional complex type (NCBI) compare
Rru_A3427 -3.6 -14.9 Tryptophan synthase, beta chain (NCBI) compare
Rru_A2507 -3.6 -15.0 Orotate phosphoribosyl transferase (NCBI) compare
Rru_A2936 -3.5 -16.2 Dihydroorotase multifunctional complex type (NCBI) compare
Rru_A0397 -3.5 -4.7 Argininosuccinate lyase (NCBI) compare
Rru_A0432 -3.1 -4.2 4-hydroxythreonine-4-phosphate dehydrogenase (NCBI) compare
Rru_A1827 -3.0 -10.8 Glycine hydroxymethyltransferase (NCBI) compare
Rru_A3596 -3.0 -7.5 Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit (NCBI) compare
Rru_A1432 -2.7 -11.7 Nicotinate-nucleotide pyrophosphorylase (NCBI) compare
Rru_A3341 -2.5 -1.7 Acetylglutamate kinase (NCBI) compare
Rru_A2847 -2.5 -3.1 Transcriptional regulators, TraR/DksA family (NCBI) compare
Rru_A1434 -2.4 -14.5 Quinolinate synthetase A (NCBI) compare
Rru_A2771 -2.3 -2.8 Histidinol dehydrogenase (NCBI) compare
Rru_A1865 -2.2 -8.3 Dihydrodipicolinate synthase subfamily (NCBI) compare
Rru_A1620 -2.0 -2.5 hypothetical protein (NCBI) compare
Rru_A2887 -2.0 -3.8 GreA/GreB family elongation factor (NCBI) compare
Rru_A0574 -2.0 -3.8 Carboxylyase-related protein (NCBI) compare
Rru_A1051 -1.9 -2.6 Phosphoribosylaminoimidazole carboxylase, ATPase subunit (NCBI) compare
Rru_A1854 -1.9 -4.8 Pyridoxal phosphate biosynthetic protein PdxJ (NCBI) compare
Rru_A0963 -1.9 -4.0 MifU-like protein, Fe-S cluster formation (NCBI) compare
Rru_A1021 -1.8 -2.7 Sigma 32 (RpoH) (NCBI) compare
Rru_A0010 -1.7 -5.5 Sigma-54 (RpoN) (NCBI) compare
Rru_A2935 -1.7 -7.2 PAS/PAC Sensor Hybrid Histidine Kinase (NCBI) compare
Rru_A1437 -1.7 -8.1 Sodium:dicarboxylate symporter (NCBI) compare
Rru_A1433 -1.6 -4.5 L-aspartate oxidase (NCBI) compare
Rru_A1890 -1.6 -2.5 hypothetical protein (NCBI) compare
Rru_A0155 -1.6 -2.3 Transcriptional Regulator, TetR family (NCBI) compare
Rru_A1435 -1.5 -6.7 Two Component, Sigma54 Specific, Transcriptional Regulator, Fis family (NCBI) compare
Rru_A3380 -1.5 -1.4 hypothetical protein (NCBI) compare
Rru_A1286 -1.5 -0.6 hypothetical protein (NCBI) compare
Rru_A3801 -1.4 -4.5 Enoyl-CoA hydratase/isomerase (NCBI) compare
Rru_A1529 -1.3 -4.9 Transcriptional Regulator, ArsR family (NCBI) compare
Rru_A0683 -1.3 -0.7 3-deoxy-7-phosphoheptulonate synthase (NCBI) compare
Rru_A2411 -1.3 -8.6 Aminotransferase, class I and II (NCBI) compare
Rru_A1775 -1.3 -2.1 chromosome segregation and condensation protein ScpA (NCBI) compare
Rru_A3010 -1.3 -5.7 Transcriptional Regulator, DeoR family (NCBI) compare
Rru_A0663 -1.2 -1.4 Cold-shock DNA-binding domain protein (NCBI) compare
Rru_A2163 -1.2 -1.3 conserved hypothetical protein RP631 (NCBI) compare
Rru_A2363 -1.1 -6.9 Endonuclease/exonuclease/phosphatase (NCBI) compare
Rru_A2100 -1.1 -5.9 Protein of unknown function DUF81 (NCBI) compare
Rru_A0484 -1.1 -3.3 hypothetical protein (NCBI) compare
Rru_A1849 -1.1 -1.6 Recombination protein O, RecO (NCBI) compare
Rru_A3533 -1.0 -7.2 hypothetical protein (NCBI) compare
Rru_A3800 -1.0 -3.5 hypothetical protein (NCBI) compare
Rru_A1208 -1.0 -4.6 AFG1-like ATPase (NCBI) compare
Rru_A2370 -1.0 -1.6 GCN5-related N-acetyltransferase (NCBI) compare
Rru_A0058 -1.0 -1.1 Dihydrokaempferol 4-reductase (NCBI) compare
Rru_A3748 -0.9 -3.1 hypothetical protein (NCBI) compare
Rru_A1179 -0.9 -1.8 Transcriptional Regulator, DeoR family (NCBI) compare
Rru_A3089 -0.9 -4.6 hypothetical protein (NCBI) compare
Rru_A1436 -0.9 -4.0 Histidine Kinase (NCBI) compare
Rru_A0752 -0.9 -2.2 hypothetical protein (NCBI) compare
Rru_A1692 -0.9 -4.8 S-adenosylmethionine decarboxylase related (NCBI) compare
Rru_A3743 -0.9 -1.3 hypothetical protein (NCBI) compare
Rru_A1366 -0.9 -6.5 Transcriptional Regulator, DeoR family (NCBI) compare
Rru_A3642 -0.8 -1.0 Negative regulator of class I heat shock protein (NCBI) compare
Rru_A1691 -0.8 -5.5 Spermine synthase (NCBI) compare
Rru_A1767 -0.8 -1.2 peptidase M23B (NCBI) compare
Rru_A3599 -0.8 -2.3 20S proteasome, A and B subunits (NCBI) compare
Rru_A3139 -0.8 -3.8 Transcriptional Regulator, GntR family (NCBI) compare
Rru_A2201 -0.8 -2.3 Peptidase S1C, Do (NCBI) compare
Rru_A0100 -0.8 -1.0 hypothetical protein (NCBI) compare
Rru_A3548 -0.8 -6.3 Magnesium-protoporphyrin IX monomethyl ester anaerobic oxidative cyclase (NCBI) compare
Rru_A1837 -0.8 -2.9 Porphobilinogen synthase (NCBI) compare
Rru_A3399 -0.8 -2.6 Transcriptional Regulator, BadM/Rrf2 family (NCBI) compare
Rru_A2244 -0.8 -6.8 Glycogen/starch/alpha-glucan phosphorylase (NCBI) compare
Rru_A3527 -0.8 -3.1 Protein of unknown function YGGT (NCBI) compare
Rru_A0181 -0.7 -2.8 hypothetical protein (NCBI) compare
Rru_A3202 -0.7 -2.5 DNA topoisomerase (NCBI) compare
Rru_A1593 -0.7 -4.2 Peptidase M50, putative membrane-associated zinc metallopeptidase (NCBI) compare
Rru_A1015 -0.7 -2.2 Binding-protein-dependent transport systems inner membrane component (NCBI) compare
Rru_A3186 -0.7 -2.1 hypothetical protein (NCBI) compare
Rru_A2167 -0.7 -1.9 Phosphoribosylformylglycinamidine cyclo-ligase (NCBI) compare
Rru_A1402 -0.7 -1.7 CheW protein (NCBI) compare
Rru_A2539 -0.7 -1.6 hypothetical protein (NCBI) compare
Rru_A2008 -0.7 -4.9 Thiamine biosynthesis protein ThiC (NCBI) compare
Rru_A3571 -0.7 -4.2 Glycerol-3-phosphate dehydrogenase (NAD(P)+) (NCBI) compare
Rru_A2770 -0.7 -1.4 Uncharacterized conserved protein UCP032146 (NCBI) compare
Rru_A1084 -0.7 -2.6 5-formyltetrahydrofolate cyclo-ligase (NCBI) compare
Rru_A1164 -0.6 -1.0 Peptidase M52, hydrogenase expression/formation protein (NCBI) compare
Rru_A1308 -0.6 -5.2 Acyl-CoA dehydrogenase (NCBI) compare
Rru_A0515 -0.6 -1.6 HAD-superfamily subfamily IIA hydrolase (NCBI) compare
Rru_A1841 -0.6 -0.9 Flavin reductase-like, FMN-binding (NCBI) compare
Rru_A3349 -0.6 -2.2 transcription activator, effector binding (NCBI) compare
Rru_A1018 -0.6 -3.8 extracellular solute-binding protein, family 1 (NCBI) compare
Rru_A0159 -0.6 -1.3 Exodeoxyribonuclease VII (NCBI) compare
Rru_A3378 -0.6 -3.3 hypothetical protein (NCBI) compare
Rru_A0006 -0.6 -1.8 Plasmid maintenance system antidote protein (NCBI) compare
Rru_A3362 -0.6 -2.7 Uroporphyrin-III C-methyltransferase-like (NCBI) compare
Rru_A2530 -0.6 -3.6 hypothetical protein (NCBI) compare
Rru_A2865 -0.6 -3.4 Peptidase M24 (NCBI) compare
Rru_A1677 -0.6 -2.0 Signal transduction histidine kinase, nitrogen specific, NtrB (NCBI) compare
Rru_A0770 -0.6 -4.1 Peptidase M23B (NCBI) compare
Rru_A2866 -0.6 -3.5 Ribosomal protein L11 methyltransferase (NCBI) compare
Rru_A2713 -0.6 -1.2 hypothetical protein (NCBI) compare
Rru_A0412 -0.6 -1.4 hypothetical protein (NCBI) compare
Rru_A0393 -0.6 -3.5 NUDIX hydrolase (NCBI) compare
Rru_A3614 -0.6 -1.7 Maf-like protein (NCBI) compare
Rru_A0148 -0.6 -2.5 GTP-binding protein TypA (NCBI) compare
Rru_A0207 -0.6 -2.3 Cobalt chelatase, CobT subunit (NCBI) compare
Rru_A3386 -0.6 -2.0 BioY protein (NCBI) compare
Rru_A0665 -0.6 -1.4 Response regulator receiver domain protein (CheY) (NCBI) compare
Rru_A3621 -0.5 -2.0 Methylated-DNA-(protein)-cysteine S-methyltransferase (NCBI) compare
Rru_A1549 -0.5 -2.7 Trigger factor (NCBI) compare
Rru_A1309 -0.5 -3.3 acetoacetyl-CoA reductase (NCBI) compare
Rru_A2037 -0.5 -2.7 hypothetical protein (NCBI) compare
Rru_A1200 -0.5 -2.6 Citrate lyase (NCBI) compare
Rru_A2115 -0.5 -3.5 Phosphoglucomutase/phosphomannomutase (NCBI) compare
Rru_A1348 -0.5 -1.4 Protein of unknown function DUF81 (NCBI) compare
Rru_A2907 -0.5 -0.8 Anti-Sigma-factor antagonist (STAS) domain protein (NCBI) compare
Rru_A3532 -0.5 -3.5 UspA (NCBI) compare
Rru_A1898 -0.5 -3.1 SOS-response transcriptional repressor, LexA (NCBI) compare
Rru_A1047 -0.5 -3.3 6-phosphofructokinase (NCBI) compare
Rru_A2182 -0.5 -2.3 NAD(P)(+) transhydrogenase (AB-specific) (NCBI) compare
Rru_A0637 -0.5 -1.4 hypothetical protein (NCBI) compare
Rru_A3455 -0.5 -2.0 Binding-protein-dependent transport systems inner membrane component (NCBI) compare
Rru_A2242 -0.5 -2.1 Glutathione-dependent formaldehyde-activating, GFA (NCBI) compare
Rru_A1136 -0.5 -4.0 Periplasmic binding protein (NCBI) compare
Rru_A2000 -0.5 -2.1 hypothetical protein (NCBI) compare
Rru_A1855 -0.5 -2.7 hypothetical protein (NCBI) compare
Rru_A1112 -0.5 -0.5 hypothetical protein (NCBI) compare
Rru_A1761 -0.5 -0.6 GCN5-related N-acetyltransferase (NCBI) compare
Rru_A2377 -0.5 -1.6 Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain (NCBI) compare
Rru_A3627 -0.5 -2.6 Cobyrinic acid a,c-diamide synthase (NCBI) compare
Rru_A1669 -0.5 -1.9 Transcriptional Regulator, MerR family (NCBI) compare
Rru_A1884 -0.5 -1.3 Periplasmic Sensor Signal Transduction Histidine Kinase (NCBI) compare
Rru_A1545 -0.5 -1.7 Putative diguanylate cyclase (GGDEF domain) (NCBI) compare
Rru_A0091 -0.5 -1.0 PilT protein-like (NCBI) compare
Rru_A0872 -0.5 -1.2 hypothetical protein (NCBI) compare
Rru_A3393 -0.5 -2.2 Penicillin-binding protein 1A (NCBI) compare
Rru_A3255 -0.5 -2.0 Protein of unknown function DUF214 (NCBI) compare
Rru_A2055 -0.5 -1.4 Peptidase S49 (NCBI) compare
Rru_A1708 -0.5 -1.9 hypothetical protein (NCBI) compare
Rru_A0483 -0.5 -0.8 hypothetical protein (NCBI) compare
Rru_A1167 -0.5 -0.7 putative hydrogenase expression/formation protein HupK (NCBI) compare
Rru_A3338 -0.5 -1.0 Protein of unknown function DUF37 (NCBI) compare
Rru_A1439 -0.5 -1.6 Putative FecR (NCBI) compare
Rru_A3528 -0.5 -1.0 hypothetical protein (NCBI) compare
Rru_A3169 -0.5 -3.1 ABC transporter component (NCBI) compare
Rru_A3218 -0.4 -1.1 hypothetical protein (NCBI) compare
Rru_A3371 -0.4 -1.9 Zinc-containing alcohol dehydrogenase superfamily (NCBI) compare
Rru_A1525 -0.4 -1.5 Nucleoside diphosphate pyrophosphatase (NCBI) compare
Rru_A1777 -0.4 -2.1 Beta-N-acetylhexosaminidase (NCBI) compare
Rru_A3468 -0.4 -2.0 Transcriptional Regulator, AsnC family (NCBI) compare
Rru_A0046 -0.4 -3.2 Protein of unknown function DUF523 (NCBI) compare
Rru_A1678 -0.4 -1.1 Nitrogen Metabolism Transcriptional Regulator, NtrC, Fis Family (NCBI) compare
Rru_A2547 -0.4 -3.5 N-formylglutamate amidohydrolase (NCBI) compare
Rru_A0537 -0.4 -1.8 Protein of unknown function DUF955 (NCBI) compare
Rru_A2800 -0.4 -1.8 hypothetical protein (NCBI) compare
Rru_A1445 -0.4 -3.3 Ribonucleoside-diphosphate reductase (NCBI) compare
Rru_B0007 -0.4 -1.7 Glycosyl transferase, group 1 (NCBI) compare
Rru_A0846 -0.4 -0.9 hypothetical protein (NCBI) compare
Rru_A3019 -0.4 -0.8 hypothetical protein (NCBI) compare
Rru_A3600 -0.4 -3.0 Heat shock protein HslU (NCBI) compare
Rru_A2813 -0.4 -1.9 Molybdopterin cofactor biosynthesis MoaC region (NCBI) compare
Rru_A3739 -0.4 -1.4 hypothetical protein (NCBI) compare
Rru_A2463 -0.4 -2.3 N-formylglutamate amidohydrolase (NCBI) compare
Rru_A2952 -0.4 -1.6 Methyltransferase small (NCBI) compare
Rru_A0643 -0.4 -2.9 Protein of unknown function DUF152 (NCBI) compare
Rru_A3222 -0.4 -1.1 transport system permease protein (NCBI) compare
Rru_A3208 -0.4 -2.3 Protein of unknown function DUF29 (NCBI) compare
Rru_A0224 -0.4 -0.6 Protein of unknown function DUF160 (NCBI) compare
Rru_A0404 -0.4 -3.4 Amidophosphoribosyl transferase (NCBI) compare
Rru_A0652 -0.4 -1.1 Pseudouridine synthase, Rsu (NCBI) compare
Rru_A2565 -0.4 -1.6 no description compare


Specific Phenotypes

None in this experiment

For Rhodospirillum rubrum S1H in carbon source experiments

For carbon source Sodium succinate dibasic hexahydrate across organisms