Experiment set7IT091 for Rhodospirillum rubrum S1H

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Succinate carbon source

200 most important genes:

  gene name fitness t score description  
Rru_A3594 -7.0 -6.8 Histidine biosynthesis protein HisF (NCBI) compare
Rru_A3276 -6.4 -5.3 Ornithine carbamoyltransferase (NCBI) compare
Rru_A1897 -6.2 -9.5 Indole-3-glycerol-phosphate synthase (NCBI) compare
Rru_A0394 -6.0 -5.8 Amino-acid N-acetyltransferase (NCBI) compare
Rru_A2885 -5.8 -21.7 Carbamoyl-phosphate synthase, small subunit (NCBI) compare
Rru_A3267 -5.7 -11.3 Methionine biosynthesis MetW (NCBI) compare
Rru_A3428 -5.7 -21.6 Tryptophan synthase (NCBI) compare
Rru_A1189 -5.6 -17.5 3-isopropylmalate dehydratase large subunit region (NCBI) compare
Rru_A3162 -5.6 -20.3 Prephenate dehydratase (NCBI) compare
Rru_A3751 -5.6 -16.0 Argininosuccinate synthase (NCBI) compare
Rru_A0468 -5.3 -7.0 Acetolactate synthase, small subunit (NCBI) compare
Rru_A2772 -5.3 -5.1 ATP phosphoribosyltransferase (NCBI) compare
Rru_A1105 -5.1 -9.3 tRNA synthetase, class II (G, H, P and S) (NCBI) compare
Rru_A2886 -5.1 -26.3 Carbamoyl-phosphate synthase, large subunit, glutamine-dependent (NCBI) compare
Rru_A2421 -5.1 -10.8 N-acetyl-gamma-glutamyl-phosphate reductase (NCBI) compare
Rru_A1239 -5.0 -8.4 Glutamate 5-kinase, ProB-related (NCBI) compare
Rru_A0469 -5.0 -17.3 Ketol-acid reductoisomerase (NCBI) compare
Rru_A0467 -5.0 -17.0 Acetolactate synthase, large subunit, biosynthetic type (NCBI) compare
Rru_A3425 -4.9 -4.7 Phosphoribosylanthranilate isomerase (NCBI) compare
Rru_A3266 -4.9 -15.8 Homoserine O-acetyltransferase (NCBI) compare
Rru_A1530 -4.9 -28.3 5,10-methylenetetrahydrofolate reductase (NCBI) compare
Rru_A1191 -4.9 -12.1 3-isopropylmalate dehydrogenase (NCBI) compare
Rru_A2549 -4.9 -11.5 HAD-superfamily hydrolase subfamily IIB (NCBI) compare
Rru_A3277 -4.8 -6.6 Acetylornithine and succinylornithine aminotransferase (NCBI) compare
Rru_A1928 -4.8 -19.4 Yeast 2-isopropylmalate synthase (NCBI) compare
Rru_A0432 -4.8 -6.5 4-hydroxythreonine-4-phosphate dehydrogenase (NCBI) compare
Rru_A1786 -4.7 -19.5 Dihydroxy-acid dehydratase (NCBI) compare
Rru_A1896 -4.7 -12.2 Anthranilate phosphoribosyl transferase (NCBI) compare
Rru_A3191 -4.5 -16.9 Dihydroorotase multifunctional complex type (NCBI) compare
Rru_A1190 -4.4 -2.7 3-isopropylmalate dehydratase small subunit region (NCBI) compare
Rru_A3264 -4.4 -12.1 Histidinol-phosphate aminotransferase (NCBI) compare
Rru_A3214 -4.4 -17.1 O-succinylhomoserine sulfhydrylase (NCBI) compare
Rru_A2936 -4.4 -13.2 Dihydroorotase multifunctional complex type (NCBI) compare
Rru_A3424 -4.2 -7.5 Orotidine-5'-phosphate decarboxylase (NCBI) compare
Rru_A3165 -4.0 -7.9 Histidinol-phosphate phosphatase, putative, inositol monophosphatase (NCBI) compare
Rru_A0514 -3.8 -10.3 Dihydroorotate dehydrogenase 2 (NCBI) compare
Rru_A1895 -3.8 -2.3 Glutamine amidotransferase of anthranilate synthase (NCBI) compare
Rru_A2507 -3.7 -18.6 Orotate phosphoribosyl transferase (NCBI) compare
Rru_A3427 -3.7 -13.9 Tryptophan synthase, beta chain (NCBI) compare
Rru_A0397 -3.2 -4.6 Argininosuccinate lyase (NCBI) compare
Rru_A3596 -3.1 -7.8 Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit (NCBI) compare
Rru_A1432 -2.8 -12.6 Nicotinate-nucleotide pyrophosphorylase (NCBI) compare
Rru_A3341 -2.7 -1.8 Acetylglutamate kinase (NCBI) compare
Rru_A1827 -2.7 -10.5 Glycine hydroxymethyltransferase (NCBI) compare
Rru_A3190 -2.6 -2.9 Aspartate carbamoyltransferase (NCBI) compare
Rru_A1434 -2.5 -13.9 Quinolinate synthetase A (NCBI) compare
Rru_A2771 -2.5 -3.7 Histidinol dehydrogenase (NCBI) compare
Rru_A1865 -2.4 -10.1 Dihydrodipicolinate synthase subfamily (NCBI) compare
Rru_A3380 -2.3 -2.2 hypothetical protein (NCBI) compare
Rru_A1620 -2.2 -3.2 hypothetical protein (NCBI) compare
Rru_A1021 -2.1 -2.5 Sigma 32 (RpoH) (NCBI) compare
Rru_A0963 -2.0 -5.4 MifU-like protein, Fe-S cluster formation (NCBI) compare
Rru_A1854 -1.9 -3.8 Pyridoxal phosphate biosynthetic protein PdxJ (NCBI) compare
Rru_A1051 -1.8 -2.5 Phosphoribosylaminoimidazole carboxylase, ATPase subunit (NCBI) compare
Rru_A1437 -1.8 -8.4 Sodium:dicarboxylate symporter (NCBI) compare
Rru_A2847 -1.8 -3.1 Transcriptional regulators, TraR/DksA family (NCBI) compare
Rru_A1890 -1.7 -2.5 hypothetical protein (NCBI) compare
Rru_A0752 -1.6 -2.9 hypothetical protein (NCBI) compare
Rru_A2935 -1.6 -6.8 PAS/PAC Sensor Hybrid Histidine Kinase (NCBI) compare
Rru_A1767 -1.6 -1.9 peptidase M23B (NCBI) compare
Rru_A1286 -1.5 -0.6 hypothetical protein (NCBI) compare
Rru_A3801 -1.5 -3.1 Enoyl-CoA hydratase/isomerase (NCBI) compare
Rru_A1433 -1.5 -6.2 L-aspartate oxidase (NCBI) compare
Rru_A1841 -1.5 -1.7 Flavin reductase-like, FMN-binding (NCBI) compare
Rru_A1529 -1.4 -5.1 Transcriptional Regulator, ArsR family (NCBI) compare
Rru_A1179 -1.4 -2.5 Transcriptional Regulator, DeoR family (NCBI) compare
Rru_A0574 -1.4 -2.7 Carboxylyase-related protein (NCBI) compare
Rru_A2887 -1.3 -2.7 GreA/GreB family elongation factor (NCBI) compare
Rru_A0683 -1.3 -0.7 3-deoxy-7-phosphoheptulonate synthase (NCBI) compare
Rru_A1436 -1.3 -5.4 Histidine Kinase (NCBI) compare
Rru_A3527 -1.3 -5.1 Protein of unknown function YGGT (NCBI) compare
Rru_A1435 -1.3 -4.8 Two Component, Sigma54 Specific, Transcriptional Regulator, Fis family (NCBI) compare
Rru_A0010 -1.2 -4.8 Sigma-54 (RpoN) (NCBI) compare
Rru_A2363 -1.2 -7.7 Endonuclease/exonuclease/phosphatase (NCBI) compare
Rru_A0206 -1.2 -2.6 Cobalt chelatase, pCobS small subunit (NCBI) compare
Rru_A2411 -1.1 -7.1 Aminotransferase, class I and II (NCBI) compare
Rru_A2100 -1.1 -7.0 Protein of unknown function DUF81 (NCBI) compare
Rru_A0224 -1.1 -1.3 Protein of unknown function DUF160 (NCBI) compare
Rru_A1208 -1.0 -5.2 AFG1-like ATPase (NCBI) compare
Rru_A2085 -1.0 -2.6 Nitrogen regulatory protein P-II (GlnB, GlnK) (NCBI) compare
Rru_A3800 -1.0 -3.7 hypothetical protein (NCBI) compare
Rru_A2201 -1.0 -3.0 Peptidase S1C, Do (NCBI) compare
Rru_A3398 -1.0 -1.4 Transcriptional Regulator, XRE family (NCBI) compare
Rru_A1837 -1.0 -4.2 Porphobilinogen synthase (NCBI) compare
Rru_A1086 -0.9 -3.4 hypothetical protein (RefSeq) compare
Rru_A0665 -0.9 -2.5 Response regulator receiver domain protein (CheY) (NCBI) compare
Rru_A3533 -0.9 -6.8 hypothetical protein (NCBI) compare
Rru_A2167 -0.9 -2.9 Phosphoribosylformylglycinamidine cyclo-ligase (NCBI) compare
Rru_A2303 -0.9 -2.1 Deoxyribose-phosphate aldolase (NCBI) compare
Rru_A1691 -0.9 -5.8 Spermine synthase (NCBI) compare
Rru_A0454 -0.9 -1.1 Leucyl aminopeptidase (NCBI) compare
Rru_A1692 -0.9 -6.3 S-adenosylmethionine decarboxylase related (NCBI) compare
Rru_A2952 -0.8 -2.9 Methyltransferase small (NCBI) compare
Rru_A1348 -0.8 -2.0 Protein of unknown function DUF81 (NCBI) compare
Rru_A1366 -0.8 -6.0 Transcriptional Regulator, DeoR family (NCBI) compare
Rru_A3571 -0.8 -4.4 Glycerol-3-phosphate dehydrogenase (NAD(P)+) (NCBI) compare
Rru_A2163 -0.8 -0.9 conserved hypothetical protein RP631 (NCBI) compare
Rru_A1788 -0.8 -1.7 Response regulator receiver domain protein (CheY) (NCBI) compare
Rru_A1084 -0.8 -3.7 5-formyltetrahydrofolate cyclo-ligase (NCBI) compare
Rru_A3548 -0.8 -5.5 Magnesium-protoporphyrin IX monomethyl ester anaerobic oxidative cyclase (NCBI) compare
Rru_A3378 -0.8 -4.1 hypothetical protein (NCBI) compare
Rru_A3743 -0.8 -1.2 hypothetical protein (NCBI) compare
Rru_A3010 -0.8 -3.8 Transcriptional Regulator, DeoR family (NCBI) compare
Rru_A1678 -0.8 -1.9 Nitrogen Metabolism Transcriptional Regulator, NtrC, Fis Family (NCBI) compare
Rru_A0023 -0.8 -2.0 hypothetical protein (NCBI) compare
Rru_A0484 -0.8 -2.7 hypothetical protein (NCBI) compare
Rru_A3614 -0.7 -2.9 Maf-like protein (NCBI) compare
Rru_A2115 -0.7 -4.8 Phosphoglucomutase/phosphomannomutase (NCBI) compare
Rru_A0661 -0.7 -3.2 Hly-III related proteins (NCBI) compare
Rru_A1648 -0.7 -1.1 Helix-turn-helix protein, CopG (NCBI) compare
Rru_A3502 -0.7 -0.8 hypothetical protein (NCBI) compare
Rru_A1308 -0.7 -5.8 Acyl-CoA dehydrogenase (NCBI) compare
Rru_B0028 -0.7 -1.9 ABC transporter related (NCBI) compare
Rru_A1776 -0.7 -2.9 Peptidase M50 (NCBI) compare
Rru_A0006 -0.7 -3.4 Plasmid maintenance system antidote protein (NCBI) compare
Rru_A2865 -0.7 -3.4 Peptidase M24 (NCBI) compare
Rru_A1771 -0.7 -1.2 Sec-independent periplasmic protein translocase (NCBI) compare
Rru_A2816 -0.7 -1.1 Transcriptional Regulator, TetR family (NCBI) compare
Rru_A2547 -0.7 -5.4 N-formylglutamate amidohydrolase (NCBI) compare
Rru_A1136 -0.6 -4.5 Periplasmic binding protein (NCBI) compare
Rru_A1669 -0.6 -2.2 Transcriptional Regulator, MerR family (NCBI) compare
Rru_A1536 -0.6 -3.4 UvrD/REP helicase (NCBI) compare
Rru_A1047 -0.6 -4.1 6-phosphofructokinase (NCBI) compare
Rru_A1677 -0.6 -2.2 Signal transduction histidine kinase, nitrogen specific, NtrB (NCBI) compare
Rru_A3599 -0.6 -2.2 20S proteasome, A and B subunits (NCBI) compare
Rru_A2244 -0.6 -5.3 Glycogen/starch/alpha-glucan phosphorylase (NCBI) compare
Rru_A2346 -0.6 -1.2 hypothetical protein (NCBI) compare
Rru_A1549 -0.6 -3.0 Trigger factor (NCBI) compare
Rru_A1545 -0.6 -2.4 Putative diguanylate cyclase (GGDEF domain) (NCBI) compare
Rru_A1593 -0.6 -3.7 Peptidase M50, putative membrane-associated zinc metallopeptidase (NCBI) compare
Rru_A3268 -0.6 -1.8 hypothetical protein (NCBI) compare
Rru_A3642 -0.6 -1.3 Negative regulator of class I heat shock protein (NCBI) compare
Rru_A3393 -0.6 -2.6 Penicillin-binding protein 1A (NCBI) compare
Rru_A0181 -0.6 -2.9 hypothetical protein (NCBI) compare
Rru_A3386 -0.6 -2.4 BioY protein (NCBI) compare
Rru_A3089 -0.6 -2.6 hypothetical protein (NCBI) compare
Rru_A3693 -0.6 -1.6 Protein of unknown function UPF0011 (NCBI) compare
Rru_A3322 -0.6 -2.1 Transcriptional Regulator, Crp/Fnr family (NCBI) compare
Rru_A1768 -0.6 -2.0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (NCBI) compare
Rru_A3338 -0.5 -1.2 Protein of unknown function DUF37 (NCBI) compare
Rru_A3399 -0.5 -2.5 Transcriptional Regulator, BadM/Rrf2 family (NCBI) compare
Rru_A2994 -0.5 -2.1 hypothetical protein (NCBI) compare
Rru_A1015 -0.5 -1.7 Binding-protein-dependent transport systems inner membrane component (NCBI) compare
Rru_A1444 -0.5 -3.8 Ribonucleoside-diphosphate reductase (NCBI) compare
Rru_A0412 -0.5 -1.3 hypothetical protein (NCBI) compare
Rru_A0643 -0.5 -3.5 Protein of unknown function DUF152 (NCBI) compare
Rru_A0207 -0.5 -1.6 Cobalt chelatase, CobT subunit (NCBI) compare
Rru_A3704 -0.5 -0.8 Periplasmic solute binding protein (NCBI) compare
Rru_A2530 -0.5 -2.9 hypothetical protein (NCBI) compare
Rru_A1126 -0.5 -1.2 ISBm1, transposase orfA (NCBI) compare
Rru_A3202 -0.5 -2.5 DNA topoisomerase (NCBI) compare
Rru_A2284 -0.5 -2.3 Dinitrogenase iron-molybdenum cofactor biosynthesis (NCBI) compare
Rru_A1900 -0.5 -0.9 Transcriptional Regulator, AsnC family (NCBI) compare
Rru_A3139 -0.5 -2.9 Transcriptional Regulator, GntR family (NCBI) compare
Rru_A0046 -0.5 -3.4 Protein of unknown function DUF523 (NCBI) compare
Rru_A1164 -0.5 -0.5 Peptidase M52, hydrogenase expression/formation protein (NCBI) compare
Rru_A2874 -0.5 -2.2 FAD dependent oxidoreductase (NCBI) compare
Rru_A0746 -0.5 -1.3 hypothetical protein (NCBI) compare
Rru_A1894 -0.5 -1.9 heavy metal translocating P-type ATPase (NCBI) compare
Rru_A0908 -0.5 -1.0 microcompartments protein (NCBI) compare
Rru_A1814 -0.5 -1.8 Carbon monoxide dehydrogenase subunit G (NCBI) compare
Rru_A1112 -0.5 -0.5 hypothetical protein (NCBI) compare
Rru_A2326 -0.5 -2.6 Response regulator receiver domain protein (CheY) (NCBI) compare
Rru_A3377 -0.5 -1.6 Alpha/beta hydrolase fold (NCBI) compare
Rru_A3621 -0.5 -2.2 Methylated-DNA-(protein)-cysteine S-methyltransferase (NCBI) compare
Rru_A2958 -0.5 -2.2 no description compare
Rru_A0387 -0.4 -2.4 Antibiotic biosynthesis monooxygenase (NCBI) compare
Rru_A3783 -0.4 -3.4 tRNA pseudouridine synthase B (NCBI) compare
Rru_A2805 -0.4 -1.6 Protein of unknown function DUF214 (NCBI) compare
Rru_A0515 -0.4 -1.2 HAD-superfamily subfamily IIA hydrolase (NCBI) compare
Rru_A3349 -0.4 -1.6 transcription activator, effector binding (NCBI) compare
Rru_A2857 -0.4 -2.9 Flagellar FlbT (NCBI) compare
Rru_A2770 -0.4 -0.8 Uncharacterized conserved protein UCP032146 (NCBI) compare
Rru_A2140 -0.4 -2.4 Transcriptional Regulator, XRE family (NCBI) compare
Rru_A0406 -0.4 -2.2 DNA repair protein RadA (NCBI) compare
Rru_A1698 -0.4 -3.1 Cation efflux protein (NCBI) compare
Rru_A1445 -0.4 -3.2 Ribonucleoside-diphosphate reductase (NCBI) compare
Rru_A3640 -0.4 -0.7 Ham1-like protein (NCBI) compare
Rru_A2800 -0.4 -2.8 hypothetical protein (NCBI) compare
Rru_A0770 -0.4 -3.6 Peptidase M23B (NCBI) compare
Rru_A0424 -0.4 -0.8 hypothetical protein (NCBI) compare
Rru_A2580 -0.4 -2.0 hypothetical protein (NCBI) compare
Rru_A3660 -0.4 -1.7 tRNA and rRNA cytosine-C5-methylase (NCBI) compare
Rru_A1402 -0.4 -1.8 CheW protein (NCBI) compare
Rru_A0404 -0.4 -3.7 Amidophosphoribosyl transferase (NCBI) compare
Rru_A1955 -0.4 -1.3 Phosphoribosyltransferase (NCBI) compare
Rru_A1518 -0.4 -0.8 hypothetical protein (NCBI) compare
Rru_A1898 -0.4 -1.3 SOS-response transcriptional repressor, LexA (NCBI) compare
Rru_A1018 -0.4 -2.7 extracellular solute-binding protein, family 1 (NCBI) compare
Rru_A1194 -0.4 -1.6 Protein of unknown function DUF134 (NCBI) compare
Rru_A3168 -0.4 -3.1 Binding-protein-dependent transport systems inner membrane component (NCBI) compare
Rru_A1137 -0.4 -3.2 transport system permease protein (NCBI) compare
Rru_A1085 -0.4 -2.2 Metallophosphoesterase (NCBI) compare
Rru_A1855 -0.4 -2.4 hypothetical protein (NCBI) compare
Rru_A3766 -0.4 -2.4 Transcriptional Regulator, MucR family (NCBI) compare
Rru_A2410 -0.4 -1.5 Homoserine dehydrogenase (NCBI) compare
Rru_A1309 -0.4 -2.2 acetoacetyl-CoA reductase (NCBI) compare
Rru_A3218 -0.4 -1.4 hypothetical protein (NCBI) compare
Rru_A1255 -0.4 -2.5 Transcriptional Regulator, GntR family (NCBI) compare
Rru_A3748 -0.4 -1.6 hypothetical protein (NCBI) compare


Specific Phenotypes

None in this experiment

For Rhodospirillum rubrum S1H in carbon source experiments

For carbon source Sodium succinate dibasic hexahydrate across organisms