Experiment set7IT088 for Methanococcus maripaludis S2

Compare to:

H2 N-free with 10mM L-Histidine

200 most detrimental genes:

  gene name fitness t score description  
MMP_RS00395 +1.1 2.3 MGMT family protein compare
MMP_RS04145 +0.8 2.0 hypothetical protein compare
MMP_RS03965 +0.8 2.5 hypothetical protein compare
MMP_RS02290 +0.8 4.6 MBL fold metallo-hydrolase compare
MMP_RS00185 +0.8 6.0 potassium channel protein compare
MMP_RS03895 +0.7 2.9 hypothetical protein compare
MMP_RS01100 +0.7 1.4 ABC transporter ATP-binding protein compare
MMP_RS08485 +0.7 3.3 tungstate ABC transporter substrate-binding protein WtpA compare
MMP_RS08370 +0.7 0.6 cation:proton antiporter subunit C compare
MMP_RS07805 +0.7 3.4 ABC transporter permease compare
MMP_RS00295 +0.6 1.4 gamma carbonic anhydrase family protein compare
MMP_RS08760 +0.6 2.3 hypothetical protein compare
MMP_RS01145 +0.6 3.7 ABC transporter ATP-binding protein compare
MMP_RS00655 +0.6 1.9 hypothetical protein compare
MMP_RS07800 +0.6 3.8 ATP-binding cassette domain-containing protein compare
MMP_RS06345 +0.6 3.9 formate dehydrogenase accessory sulfurtransferase FdhD compare
MMP_RS02900 +0.6 0.5 imidazoleglycerol-phosphate dehydratase HisB compare
MMP_RS00290 +0.6 2.7 hypothetical protein compare
MMP_RS07425 +0.6 2.2 GTP-binding protein compare
MMP_RS05365 +0.6 2.0 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH compare
MMP_RS01675 +0.6 1.3 hypothetical protein compare
MMP_RS04885 +0.6 4.2 sulfite exporter TauE/SafE family protein compare
MMP_RS02475 +0.5 1.8 hypothetical protein compare
MMP_RS08930 +0.5 1.1 hypothetical protein compare
MMP_RS06500 +0.5 2.9 ATP-binding protein compare
MMP_RS03785 +0.5 2.4 cupin domain-containing protein compare
MMP_RS00130 +0.5 0.9 nickel-responsive transcriptional regulator NikR compare
MMP_RS08640 +0.5 3.6 TIM barrel protein compare
MMP_RS03300 +0.5 0.5 TOBE domain-containing protein compare
MMP_RS08670 +0.5 2.5 metallophosphoesterase compare
MMP_RS01135 +0.5 3.4 molybdate ABC transporter substrate-binding protein compare
MMP_RS06910 +0.5 2.6 RlmF-related methyltransferase compare
MMP_RS06770 +0.5 3.2 DHH family phosphoesterase compare
MMP_RS05970 +0.5 1.5 class II SORL domain-containing protein compare
MMP_RS01270 +0.5 3.2 prepilin peptidase compare
MMP_RS08600 +0.5 1.4 flagellar protein D compare
MMP_RS00855 +0.5 2.6 DUF367 family protein compare
MMP_RS07620 +0.4 1.9 energy-coupling factor ABC transporter substrate-binding protein compare
MMP_RS02985 +0.4 1.3 hypothetical protein compare
MMP_RS06440 +0.4 2.5 CBS domain-containing protein compare
MMP_RS01630 +0.4 2.8 N-glycosylase/DNA lyase compare
MMP_RS00660 +0.4 3.2 alkaline phosphatase family protein compare
MMP_RS03560 +0.4 3.4 Na+/H+ antiporter NhaC family protein compare
MMP_RS06720 +0.4 3.0 response regulator transcription factor compare
MMP_RS08665 +0.4 3.2 hypothetical protein compare
MMP_RS01620 +0.4 1.8 hypothetical protein compare
MMP_RS01280 +0.4 3.0 DUF515 domain-containing protein compare
MMP_RS07615 +0.4 1.8 energy-coupling factor ABC transporter permease compare
MMP_RS06715 +0.4 3.1 cache domain-containing protein compare
MMP_RS03840 +0.4 1.8 hypothetical protein compare
MMP_RS08555 +0.4 1.5 hypothetical protein compare
MMP_RS00950 +0.4 1.8 site-2 protease family protein compare
MMP_RS06540 +0.4 1.0 3-methyl-2-oxobutanoate dehydrogenase subunit VorB compare
MMP_RS06760 +0.4 1.5 hypothetical protein compare
MMP_RS08990 +0.4 1.8 hypothetical protein compare
MMP_RS01635 +0.4 2.1 thiamine pyrophosphate-dependent enzyme compare
MMP_RS08280 +0.4 1.4 proteasome assembly chaperone family protein compare
MMP_RS05695 +0.4 2.5 phospholipase D-like domain-containing protein compare
MMP_RS02385 +0.4 2.4 ATP-binding protein compare
MMP_RS01155 +0.4 1.7 XRE family transcriptional regulator compare
MMP_RS00665 +0.4 1.8 hypothetical protein compare
MMP_RS04520 +0.4 1.3 nucleoside deaminase compare
MMP_RS00335 +0.4 1.3 5-amino-6-(D-ribitylamino)uracil--L-tyrosine 4-hydroxyphenyl transferase CofH compare
MMP_RS01460 +0.4 1.0 hypothetical protein compare
MMP_RS05155 +0.4 1.9 hypothetical protein compare
MMP_RS01055 +0.4 1.1 hypothetical protein compare
MMP_RS01125 +0.4 1.9 thioredoxin family protein compare
MMP_RS00305 +0.4 0.7 phosphoribosyl-ATP diphosphatase compare
MMP_RS02915 +0.4 2.2 amino acid ABC transporter permease compare
MMP_RS08855 +0.3 2.1 hypothetical protein compare
MMP_RS00155 +0.3 1.5 heavy metal-binding domain-containing protein compare
MMP_RS00385 +0.3 2.2 P-II family nitrogen regulator compare
MMP_RS09030 +0.3 1.9 hypothetical protein compare
MMP_RS01210 +0.3 2.1 sodium:solute symporter compare
MMP_RS00345 +0.3 2.2 DUF2666 domain-containing protein compare
MMP_RS08365 +0.3 1.5 energy conserving hydrogenase EhbF compare
MMP_RS01435 +0.3 1.8 DMT family transporter compare
MMP_RS02740 +0.3 1.2 hypothetical protein compare
MMP_RS05675 +0.3 1.1 phosphate ABC transporter ATP-binding protein PstB compare
MMP_RS07915 +0.3 1.8 DUF4870 domain-containing protein compare
MMP_RS00940 +0.3 1.8 daunorubicin resistance protein DrrA family ABC transporter ATP-binding protein compare
MMP_RS06575 +0.3 1.2 fluoride efflux transporter CrcB compare
MMP_RS01140 +0.3 1.7 molybdate ABC transporter permease subunit compare
MMP_RS00700 +0.3 1.8 OB-fold nucleic acid binding domain-containing protein compare
MMP_RS06150 +0.3 1.8 hypothetical protein compare
MMP_RS04165 +0.3 1.9 TetR/AcrR family transcriptional regulator compare
MMP_RS01685 +0.3 1.2 indolepyruvate oxidoreductase subunit beta compare
MMP_RS04945 +0.3 1.7 hypothetical protein compare
MMP_RS08605 +0.3 1.6 flagellar protein E compare
MMP_RS07770 +0.3 1.5 alanine racemase compare
MMP_RS03150 +0.3 2.0 phosphoglycerate mutase compare
MMP_RS03555 +0.3 1.6 transcriptional regulator compare
MMP_RS03340 +0.3 0.3 ABC transporter ATP-binding protein compare
MMP_RS01640 +0.3 2.0 2-oxoacid:acceptor oxidoreductase subunit alpha compare
MMP_RS00650 +0.3 2.1 ABC transporter ATP-binding protein compare
MMP_RS05355 +0.3 0.4 hypothetical protein compare
MMP_RS08580 +0.3 0.7 flagellin compare
MMP_RS00085 +0.3 2.1 DNA cytosine methyltransferase compare
MMP_RS06605 +0.3 2.0 DUF5814 domain-containing protein compare
MMP_RS04610 +0.3 0.9 Dabb family protein compare
MMP_RS06570 +0.3 1.0 DUF190 domain-containing protein compare
MMP_RS03390 +0.3 1.7 malate dehydrogenase compare
MMP_RS08265 +0.3 1.1 rubrerythrin compare
MMP_RS05110 +0.3 2.0 16S ribosomal RNA methyltransferase A compare
MMP_RS00990 +0.3 0.8 hypothetical protein compare
MMP_RS01115 +0.3 1.4 molybdopterin molybdotransferase MoeA compare
MMP_RS01130 +0.3 1.8 flavoprotein compare
MMP_RS06140 +0.3 1.5 radical SAM protein compare
MMP_RS07580 +0.3 1.0 DUF356 domain-containing protein compare
MMP_RS07840 +0.3 1.1 ribonuclease III compare
MMP_RS01275 +0.3 1.1 class III signal peptide-containing protein compare
MMP_RS03215 +0.3 1.9 MBL fold metallo-hydrolase compare
MMP_RS06925 +0.3 0.8 ribonuclease VapC4 compare
MMP_RS02770 +0.3 1.3 hypothetical protein compare
MMP_RS08455 +0.3 1.1 multiprotein bridging factor aMBF1 compare
MMP_RS03740 +0.3 1.2 indolepyruvate oxidoreductase subunit beta compare
MMP_RS07970 +0.3 0.9 hypothetical protein compare
MMP_RS07645 +0.3 1.2 aldehyde dehydrogenase family protein compare
MMP_RS00240 +0.3 1.9 type II secretion system F family protein compare
MMP_RS00570 +0.3 0.6 protein-L-isoaspartate O-methyltransferase compare
MMP_RS05140 +0.3 0.7 helix-turn-helix transcriptional regulator compare
MMP_RS05795 +0.3 1.6 redox-regulated ATPase YchF compare
MMP_RS01060 +0.3 1.7 calcium/sodium antiporter compare
MMP_RS06050 +0.3 1.5 ZIP family metal transporter compare
MMP_RS01985 +0.2 1.1 F420-dependent methylenetetrahydromethanopterin dehydrogenase compare
MMP_RS08070 +0.2 1.0 DUF2096 domain-containing protein compare
MMP_RS02375 +0.2 1.6 hypothetical protein compare
MMP_RS02305 +0.2 1.8 DUF378 domain-containing protein compare
MMP_RS00400 +0.2 1.1 tributyrin esterase compare
MMP_RS03220 +0.2 0.9 RNA 2' 3'-cyclic phosphodiesterase compare
MMP_RS01805 +0.2 0.6 NUDIX hydrolase compare
MMP_RS03065 +0.2 0.8 AzlC family ABC transporter permease compare
MMP_RS06185 +0.2 1.1 thermonuclease family protein compare
MMP_RS05820 +0.2 1.5 RNA-binding transcriptional accessory protein compare
MMP_RS06685 +0.2 1.6 formate dehydrogenase H subunit alpha selenocysteine-containing compare
MMP_RS08285 +0.2 1.3 serine/threonine protein kinase compare
MMP_RS05525 +0.2 1.1 calcium/sodium antiporter compare
MMP_RS02310 +0.2 0.5 RimK-like ATPgrasp N-terminal domain-containing protein compare
MMP_RS03490 +0.2 0.5 DUF2115 domain-containing protein compare
MMP_RS06190 +0.2 1.5 tRNA (N6-threonylcarbamoyladenosine(37)-N6)-methyltransferase TrmO compare
MMP_RS04530 +0.2 1.3 ABC transporter permease compare
MMP_RS05720 +0.2 0.9 signal recognition particle subunit SRP19/SEC65 family protein compare
MMP_RS00800 +0.2 1.4 Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain compare
MMP_RS03760 +0.2 1.4 hypothetical protein compare
MMP_RS06675 +0.2 1.3 ADP-specific phosphofructokinase compare
MMP_RS08405 +0.2 1.4 MFS transporter compare
MMP_RS01310 +0.2 1.7 hypothetical protein compare
MMP_RS00380 +0.2 1.1 P-II family nitrogen regulator compare
MMP_RS05715 +0.2 1.1 hypothetical protein compare
MMP_RS01550 +0.2 1.4 DUF1624 domain-containing protein compare
MMP_RS00960 +0.2 0.7 iron export ABC transporter permease subunit FetB compare
MMP_RS06990 +0.2 0.8 CatB-related O-acetyltransferase compare
MMP_RS07095 +0.2 1.1 PspC domain-containing protein compare
MMP_RS05435 +0.2 1.2 5'/3'-nucleotidase SurE compare
MMP_RS00120 +0.2 1.1 LysR family transcriptional regulator compare
MMP_RS00245 +0.2 1.8 type II secretion system F family protein compare
MMP_RS05235 +0.2 1.3 exodeoxyribonuclease III compare
MMP_RS06225 +0.2 1.1 DNA double-strand break repair nuclease NurA compare
MMP_RS08090 +0.2 0.9 hypothetical protein compare
MMP_RS04595 +0.2 1.1 hypothetical protein compare
MMP_RS00100 +0.2 1.4 tRNA pseudouridine(13) synthase TruD compare
MMP_RS08700 +0.2 1.2 hypothetical protein compare
MMP_RS01320 +0.2 0.9 hypothetical protein compare
MMP_RS09045 +0.2 1.5 class III signal peptide-containing protein compare
MMP_RS05785 +0.2 1.5 ATP-binding protein compare
MMP_RS00635 +0.2 0.6 energy-coupling factor transporter transmembrane protein EcfT compare
MMP_RS07625 +0.2 0.7 cobalt ECF transporter T component CbiQ compare
MMP_RS07890 +0.2 0.6 OB-fold nucleic acid binding domain-containing protein compare
MMP_RS01645 +0.2 0.7 SWIM zinc finger family protein compare
MMP_RS04995 +0.2 1.3 hypothetical protein compare
MMP_RS01120 +0.2 1.3 permease compare
MMP_RS00630 +0.2 1.2 ECF transporter S component compare
MMP_RS01855 +0.2 1.0 2-hydroxyacyl-CoA dehydratase family protein compare
MMP_RS00930 +0.2 1.0 ABC transporter permease compare
MMP_RS04960 +0.2 1.3 cytochrome c biogenesis CcdA family protein compare
MMP_RS01785 +0.2 0.9 hypothetical protein compare
MMP_RS07775 +0.2 1.0 alanine dehydrogenase compare
MMP_RS07880 +0.2 0.9 AAA family ATPase compare
MMP_RS04800 +0.2 1.0 chemotaxis protein CheW compare
MMP_RS04205 +0.2 1.3 carboxymuconolactone decarboxylase family protein compare
MMP_RS08750 +0.2 0.9 hypothetical protein compare
MMP_RS04300 +0.2 1.3 hypothetical protein compare
MMP_RS08275 +0.2 1.1 hypothetical protein compare
MMP_RS04475 +0.2 1.1 nitrogen fixation compare
MMP_RS00145 +0.2 1.1 ATP-dependent Clp protease proteolytic subunit compare
MMP_RS01660 +0.2 0.7 hypothetical protein compare
MMP_RS06305 +0.2 0.9 transporter substrate-binding domain-containing protein compare
MMP_RS02490 +0.2 0.8 hypothetical protein compare
MMP_RS03780 +0.2 1.0 4Fe-4S binding protein compare
MMP_RS03575 +0.2 1.2 ECF transporter S component compare
MMP_RS05950 +0.2 1.2 nickel-dependent hydrogenase large subunit compare
MMP_RS04100 +0.2 0.7 hypothetical protein compare
MMP_RS07590 +0.2 1.2 hypothetical protein compare
MMP_RS06965 +0.2 1.1 TIGR04014 family B12-binding domain/radical SAM domain-containing protein compare
MMP_RS01065 +0.2 1.4 alpha/beta hydrolase compare
MMP_RS02635 +0.2 1.2 class I SAM-dependent methyltransferase compare
MMP_RS08310 +0.2 0.4 TMEM165/GDT1 family protein compare
MMP_RS02450 +0.2 0.7 hypothetical protein compare
MMP_RS03160 +0.2 1.3 class III signal peptide-containing protein compare
MMP_RS08480 +0.2 0.9 molybdate ABC transporter substrate-binding protein compare


Specific Phenotypes

For 1 genes in this experiment

For nitrogen source L-Histidine in Methanococcus maripaludis S2

For nitrogen source L-Histidine across organisms