Experiment set7IT084 for Rhodospirillum rubrum S1H

Compare to:

Succinate carbon source_noKan

200 most important genes:

  gene name fitness t score description  
Rru_A3425 -7.4 -8.7 Phosphoribosylanthranilate isomerase (NCBI) compare
Rru_A1239 -6.8 -6.6 Glutamate 5-kinase, ProB-related (NCBI) compare
Rru_A1189 -6.5 -15.1 3-isopropylmalate dehydratase large subunit region (NCBI) compare
Rru_A3751 -6.2 -14.5 Argininosuccinate synthase (NCBI) compare
Rru_A1928 -5.7 -15.7 Yeast 2-isopropylmalate synthase (NCBI) compare
Rru_A3162 -5.5 -19.7 Prephenate dehydratase (NCBI) compare
Rru_A1897 -5.5 -8.4 Indole-3-glycerol-phosphate synthase (NCBI) compare
Rru_A3428 -5.4 -18.0 Tryptophan synthase (NCBI) compare
Rru_A0397 -5.4 -9.3 Argininosuccinate lyase (NCBI) compare
Rru_A1105 -5.2 -3.6 tRNA synthetase, class II (G, H, P and S) (NCBI) compare
Rru_A2885 -5.2 -21.9 Carbamoyl-phosphate synthase, small subunit (NCBI) compare
Rru_A0467 -5.2 -20.5 Acetolactate synthase, large subunit, biosynthetic type (NCBI) compare
Rru_A1896 -5.1 -11.3 Anthranilate phosphoribosyl transferase (NCBI) compare
Rru_A0394 -5.0 -6.0 Amino-acid N-acetyltransferase (NCBI) compare
Rru_A2886 -5.0 -24.6 Carbamoyl-phosphate synthase, large subunit, glutamine-dependent (NCBI) compare
Rru_A2772 -4.9 -3.4 ATP phosphoribosyltransferase (NCBI) compare
Rru_A0469 -4.8 -17.5 Ketol-acid reductoisomerase (NCBI) compare
Rru_A1786 -4.8 -23.4 Dihydroxy-acid dehydratase (NCBI) compare
Rru_A0468 -4.8 -6.3 Acetolactate synthase, small subunit (NCBI) compare
Rru_A3276 -4.7 -5.5 Ornithine carbamoyltransferase (NCBI) compare
Rru_A3266 -4.7 -11.5 Homoserine O-acetyltransferase (NCBI) compare
Rru_A3267 -4.7 -8.3 Methionine biosynthesis MetW (NCBI) compare
Rru_A3341 -4.6 -3.2 Acetylglutamate kinase (NCBI) compare
Rru_A1530 -4.5 -19.9 5,10-methylenetetrahydrofolate reductase (NCBI) compare
Rru_A3264 -4.5 -5.4 Histidinol-phosphate aminotransferase (NCBI) compare
Rru_A1191 -4.5 -12.5 3-isopropylmalate dehydrogenase (NCBI) compare
Rru_A2549 -4.4 -9.0 HAD-superfamily hydrolase subfamily IIB (NCBI) compare
Rru_A3594 -4.4 -2.9 Histidine biosynthesis protein HisF (NCBI) compare
Rru_A1190 -4.3 -2.6 3-isopropylmalate dehydratase small subunit region (NCBI) compare
Rru_A3191 -3.8 -17.1 Dihydroorotase multifunctional complex type (NCBI) compare
Rru_A3427 -3.7 -14.5 Tryptophan synthase, beta chain (NCBI) compare
Rru_A3277 -3.7 -8.2 Acetylornithine and succinylornithine aminotransferase (NCBI) compare
Rru_A3214 -3.7 -14.7 O-succinylhomoserine sulfhydrylase (NCBI) compare
Rru_A1895 -3.6 -2.2 Glutamine amidotransferase of anthranilate synthase (NCBI) compare
Rru_A3596 -3.6 -5.9 Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit (NCBI) compare
Rru_A0514 -3.6 -10.3 Dihydroorotate dehydrogenase 2 (NCBI) compare
Rru_A2936 -3.5 -7.9 Dihydroorotase multifunctional complex type (NCBI) compare
Rru_A2421 -3.5 -6.2 N-acetyl-gamma-glutamyl-phosphate reductase (NCBI) compare
Rru_A3190 -3.4 -3.3 Aspartate carbamoyltransferase (NCBI) compare
Rru_A2507 -3.4 -17.3 Orotate phosphoribosyl transferase (NCBI) compare
Rru_A3380 -3.4 -3.8 hypothetical protein (NCBI) compare
Rru_A3165 -3.2 -5.2 Histidinol-phosphate phosphatase, putative, inositol monophosphatase (NCBI) compare
Rru_A3424 -2.7 -2.6 Orotidine-5'-phosphate decarboxylase (NCBI) compare
Rru_A2771 -2.7 -4.0 Histidinol dehydrogenase (NCBI) compare
Rru_A1827 -2.5 -6.5 Glycine hydroxymethyltransferase (NCBI) compare
Rru_A1432 -2.4 -12.2 Nicotinate-nucleotide pyrophosphorylase (NCBI) compare
Rru_A1620 -2.4 -4.2 hypothetical protein (NCBI) compare
Rru_A1084 -2.2 -5.4 5-formyltetrahydrofolate cyclo-ligase (NCBI) compare
Rru_A0265 -2.2 -5.2 Electron-transferring-flavoproteindehydrogenase (NCBI) compare
Rru_A0963 -2.2 -7.3 MifU-like protein, Fe-S cluster formation (NCBI) compare
Rru_A1434 -2.1 -15.5 Quinolinate synthetase A (NCBI) compare
Rru_A3801 -2.1 -3.8 Enoyl-CoA hydratase/isomerase (NCBI) compare
Rru_A2167 -2.1 -3.9 Phosphoribosylformylglycinamidine cyclo-ligase (NCBI) compare
Rru_A1051 -2.0 -2.3 Phosphoribosylaminoimidazole carboxylase, ATPase subunit (NCBI) compare
Rru_A0432 -2.0 -5.7 4-hydroxythreonine-4-phosphate dehydrogenase (NCBI) compare
Rru_A1865 -1.7 -9.1 Dihydrodipicolinate synthase subfamily (NCBI) compare
Rru_A1841 -1.6 -1.8 Flavin reductase-like, FMN-binding (NCBI) compare
Rru_A0683 -1.6 -1.0 3-deoxy-7-phosphoheptulonate synthase (NCBI) compare
Rru_A1854 -1.6 -4.9 Pyridoxal phosphate biosynthetic protein PdxJ (NCBI) compare
Rru_A1529 -1.6 -5.5 Transcriptional Regulator, ArsR family (NCBI) compare
Rru_A1085 -1.6 -5.2 Metallophosphoesterase (NCBI) compare
Rru_A0010 -1.5 -4.4 Sigma-54 (RpoN) (NCBI) compare
Rru_A2847 -1.5 -3.1 Transcriptional regulators, TraR/DksA family (NCBI) compare
Rru_A3642 -1.4 -2.1 Negative regulator of class I heat shock protein (NCBI) compare
Rru_A3571 -1.4 -4.8 Glycerol-3-phosphate dehydrogenase (NAD(P)+) (NCBI) compare
Rru_A3704 -1.4 -3.4 Periplasmic solute binding protein (NCBI) compare
Rru_B0050 -1.3 -1.9 dTDP-glucose 4,6-dehydratase (NCBI) compare
Rru_A1437 -1.3 -5.1 Sodium:dicarboxylate symporter (NCBI) compare
Rru_A1436 -1.3 -4.2 Histidine Kinase (NCBI) compare
Rru_A2411 -1.2 -6.9 Aminotransferase, class I and II (NCBI) compare
Rru_A0404 -1.2 -9.9 Amidophosphoribosyl transferase (NCBI) compare
Rru_A1775 -1.2 -1.9 chromosome segregation and condensation protein ScpA (NCBI) compare
Rru_A1849 -1.2 -2.1 Recombination protein O, RecO (NCBI) compare
Rru_A2574 -1.2 -1.8 Transcriptional Regulator, BadM/Rrf2 family (NCBI) compare
Rru_A2994 -1.2 -2.5 hypothetical protein (NCBI) compare
Rru_A0399 -1.2 -3.5 Phosphoesterase, PA-phosphatase related (NCBI) compare
Rru_A1208 -1.1 -4.9 AFG1-like ATPase (NCBI) compare
Rru_A1019 -1.1 -3.2 FAD dependent oxidoreductase (NCBI) compare
Rru_A3533 -1.1 -8.1 hypothetical protein (NCBI) compare
Rru_A0574 -1.1 -3.1 Carboxylyase-related protein (NCBI) compare
Rru_A3010 -1.1 -6.0 Transcriptional Regulator, DeoR family (NCBI) compare
Rru_A1433 -1.1 -3.1 L-aspartate oxidase (NCBI) compare
Rru_A2100 -1.1 -7.0 Protein of unknown function DUF81 (NCBI) compare
Rru_A3202 -1.1 -5.5 DNA topoisomerase (NCBI) compare
Rru_A0596 -1.0 -2.5 Fructose-bisphosphate aldolase, class II, Calvin cycle subtype (NCBI) compare
Rru_A0118 -1.0 -1.6 type II secretion system protein E (NCBI) compare
Rru_A2370 -1.0 -1.5 GCN5-related N-acetyltransferase (NCBI) compare
Rru_A3748 -1.0 -3.9 hypothetical protein (NCBI) compare
Rru_A1552 -1.0 -1.6 Peptidase S16, ATP-dependent protease La (NCBI) compare
Rru_A0454 -1.0 -2.3 Leucyl aminopeptidase (NCBI) compare
Rru_A1435 -1.0 -2.6 Two Component, Sigma54 Specific, Transcriptional Regulator, Fis family (NCBI) compare
Rru_A0073 -1.0 -3.7 ribosomal subunit interface protein, putative (NCBI) compare
Rru_A1179 -1.0 -1.8 Transcriptional Regulator, DeoR family (NCBI) compare
Rru_A0746 -1.0 -2.1 hypothetical protein (NCBI) compare
Rru_A0643 -1.0 -4.7 Protein of unknown function DUF152 (NCBI) compare
Rru_A0006 -1.0 -3.7 Plasmid maintenance system antidote protein (NCBI) compare
Rru_A1669 -1.0 -2.7 Transcriptional Regulator, MerR family (NCBI) compare
Rru_A2244 -0.9 -7.5 Glycogen/starch/alpha-glucan phosphorylase (NCBI) compare
Rru_A0700 -0.9 -1.1 Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain (NCBI) compare
Rru_A2547 -0.9 -7.1 N-formylglutamate amidohydrolase (NCBI) compare
Rru_A1308 -0.9 -7.4 Acyl-CoA dehydrogenase (NCBI) compare
Rru_A1309 -0.9 -4.8 acetoacetyl-CoA reductase (NCBI) compare
Rru_A1527 -0.9 -5.7 ABC transporter component (NCBI) compare
Rru_A2800 -0.9 -2.3 hypothetical protein (NCBI) compare
Rru_A2085 -0.9 -2.2 Nitrogen regulatory protein P-II (GlnB, GlnK) (NCBI) compare
Rru_A3782 -0.9 -3.2 Ribosome-binding factor A (NCBI) compare
Rru_A3378 -0.8 -3.4 hypothetical protein (NCBI) compare
Rru_A3739 -0.8 -3.0 hypothetical protein (NCBI) compare
Rru_A3329 -0.8 -2.6 hypothetical protein (NCBI) compare
Rru_A2770 -0.8 -1.9 Uncharacterized conserved protein UCP032146 (NCBI) compare
Rru_A1047 -0.8 -5.2 6-phosphofructokinase (NCBI) compare
Rru_A0398 -0.8 -3.3 Thiol-disulfide isomerase and thioredoxins-like (NCBI) compare
Rru_A3743 -0.8 -1.0 hypothetical protein (NCBI) compare
Rru_A2182 -0.8 -2.3 NAD(P)(+) transhydrogenase (AB-specific) (NCBI) compare
Rru_A0696 -0.8 -1.6 RNA methyltransferase TrmH, group 1 (NCBI) compare
Rru_A2907 -0.7 -1.1 Anti-Sigma-factor antagonist (STAS) domain protein (NCBI) compare
Rru_A1537 -0.7 -1.5 hypothetical protein (NCBI) compare
Rru_A2865 -0.7 -3.7 Peptidase M24 (NCBI) compare
Rru_A2901 -0.7 -1.5 Histidine triad (HIT) protein (NCBI) compare
Rru_A1137 -0.7 -5.6 transport system permease protein (NCBI) compare
Rru_A1382 -0.7 -2.1 Butyrate-acetoacetate CoA-transferase (NCBI) compare
Rru_A2760 -0.7 -0.3 hypothetical protein (NCBI) compare
Rru_A3783 -0.7 -5.3 tRNA pseudouridine synthase B (NCBI) compare
Rru_A3393 -0.7 -3.3 Penicillin-binding protein 1A (NCBI) compare
Rru_A0908 -0.7 -0.9 microcompartments protein (NCBI) compare
Rru_A0412 -0.7 -1.8 hypothetical protein (NCBI) compare
Rru_A3548 -0.7 -5.4 Magnesium-protoporphyrin IX monomethyl ester anaerobic oxidative cyclase (NCBI) compare
Rru_A2115 -0.7 -4.3 Phosphoglucomutase/phosphomannomutase (NCBI) compare
Rru_A0645 -0.7 -1.1 Ribose-phosphate pyrophosphokinase (NCBI) compare
Rru_A1074 -0.7 -1.3 MotA/TolQ/ExbB proton channel family protein (NCBI) compare
Rru_A2530 -0.7 -3.9 hypothetical protein (NCBI) compare
Rru_A1884 -0.7 -1.6 Periplasmic Sensor Signal Transduction Histidine Kinase (NCBI) compare
Rru_A3054 -0.7 -1.4 Ribonuclease H (NCBI) compare
Rru_A1136 -0.6 -4.7 Periplasmic binding protein (NCBI) compare
Rru_A1218 -0.6 -1.2 phage shock protein A, PspA (NCBI) compare
Rru_A3322 -0.6 -2.7 Transcriptional Regulator, Crp/Fnr family (NCBI) compare
Rru_A0644 -0.6 -2.4 hypothetical protein (NCBI) compare
Rru_A3547 -0.6 -2.5 hypothetical protein (NCBI) compare
Rru_A3766 -0.6 -2.8 Transcriptional Regulator, MucR family (NCBI) compare
Rru_A1048 -0.6 -2.0 Protein of unknown function DUF465 (NCBI) compare
Rru_A2181 -0.6 -4.7 NAD(P) transhydrogenase, beta subunit (NCBI) compare
Rru_A0296 -0.6 -3.4 hypothetical protein (NCBI) compare
Rru_A1950 -0.6 -0.7 Transcriptional regulator, ModE family (NCBI) compare
Rru_A2163 -0.6 -1.1 conserved hypothetical protein RP631 (NCBI) compare
Rru_A3398 -0.6 -1.3 Transcriptional Regulator, XRE family (NCBI) compare
Rru_A3773 -0.6 -1.6 CBS domain protein (NCBI) compare
Rru_A1955 -0.6 -1.2 Phosphoribosyltransferase (NCBI) compare
Rru_A2469 -0.6 -1.6 FeoA (NCBI) compare
Rru_A1761 -0.6 -1.0 GCN5-related N-acetyltransferase (NCBI) compare
Rru_B0025 -0.6 -2.2 hypothetical protein (NCBI) compare
Rru_A0537 -0.6 -1.6 Protein of unknown function DUF955 (NCBI) compare
Rru_A2140 -0.6 -3.1 Transcriptional Regulator, XRE family (NCBI) compare
Rru_A3255 -0.5 -2.2 Protein of unknown function DUF214 (NCBI) compare
Rru_A3172 -0.5 -1.5 Lysine exporter protein (LYSE/YGGA) (NCBI) compare
Rru_A0770 -0.5 -4.3 Peptidase M23B (NCBI) compare
Rru_A3275 -0.5 -1.8 Hsp33 protein (NCBI) compare
Rru_A3502 -0.5 -0.6 hypothetical protein (NCBI) compare
Rru_A1593 -0.5 -3.2 Peptidase M50, putative membrane-associated zinc metallopeptidase (NCBI) compare
Rru_A1607 -0.5 -4.3 4-alpha-glucanotransferase (NCBI) compare
Rru_A3139 -0.5 -2.4 Transcriptional Regulator, GntR family (NCBI) compare
Rru_A2478 -0.5 -3.4 ArgK protein (NCBI) compare
Rru_A1327 -0.5 -2.2 hypothetical protein (NCBI) compare
Rru_A1691 -0.5 -3.0 Spermine synthase (NCBI) compare
Rru_A1063 -0.5 -0.9 putative transcription regulator protein (NCBI) compare
Rru_A2057 -0.5 -0.8 Molybdopterin-guanine dinucleotide biosynthesis MobB region (NCBI) compare
Rru_A2141 -0.5 -2.6 Protein of unknown function DUF6, transmembrane (NCBI) compare
Rru_A0096 -0.5 -1.6 Secretion protein HlyD (NCBI) compare
Rru_A0712 -0.5 -1.0 Transcriptional Regulator, XRE family (NCBI) compare
Rru_A3528 -0.5 -2.1 hypothetical protein (NCBI) compare
Rru_A1536 -0.5 -2.3 UvrD/REP helicase (NCBI) compare
Rru_A3752 -0.5 -1.9 Protein of unknown function DUF302 (NCBI) compare
Rru_A0998 -0.5 -2.1 NifT/FixU (NCBI) compare
Rru_A1086 -0.5 -1.8 hypothetical protein (RefSeq) compare
Rru_A3627 -0.5 -2.7 Cobyrinic acid a,c-diamide synthase (NCBI) compare
Rru_A2729 -0.5 -1.7 hypothetical protein (NCBI) compare
Rru_A1890 -0.5 -1.8 hypothetical protein (NCBI) compare
Rru_A2887 -0.5 -1.0 GreA/GreB family elongation factor (NCBI) compare
Rru_A0605 -0.5 -1.9 hypothetical protein (NCBI) compare
Rru_A2866 -0.5 -3.0 Ribosomal protein L11 methyltransferase (NCBI) compare
Rru_A1891 -0.5 -4.0 Anthranilate synthase component I (NCBI) compare
Rru_A2723 -0.5 -1.2 Rubrerythrin (NCBI) compare
Rru_A1164 -0.5 -0.9 Peptidase M52, hydrogenase expression/formation protein (NCBI) compare
Rru_A3467 -0.5 -2.4 Amidinotransferase (NCBI) compare
Rru_A2986 -0.5 -2.9 Fumarate reductase/succinate dehydrogenase flavoprotein-like (NCBI) compare
Rru_A2703 -0.5 -2.6 RNA methyltransferase TrmH, group 3 (NCBI) compare
Rru_A3614 -0.5 -1.6 Maf-like protein (NCBI) compare
Rru_A3558 -0.5 -1.3 Protein of unknown function UPF0005 (NCBI) compare
Rru_A0323 -0.5 -2.1 4Fe-4S ferredoxin, iron-sulfur binding (NCBI) compare
Rru_A0341 -0.5 -0.9 hypothetical protein (NCBI) compare
Rru_A3676 -0.5 -3.2 TRAP dicarboxylate transporter, DctM subunit (NCBI) compare
Rru_A0389 -0.5 -1.1 Antibiotic biosynthesis monooxygenase (NCBI) compare
Rru_A2939 -0.5 -1.6 hypothetical protein (NCBI) compare
Rru_A3532 -0.5 -2.6 UspA (NCBI) compare
Rru_A1380 -0.5 -0.8 Acetyl-CoA C-acetyltransferase (NCBI) compare
Rru_B0032 -0.5 -1.8 hypothetical protein (NCBI) compare
Rru_A1138 -0.5 -1.7 ABC transporter component (NCBI) compare
Rru_A3677 -0.5 -1.4 Tripartite ATP-independent periplasmic transporter, DctQ component (NCBI) compare
Rru_A2183 -0.5 -3.0 NAD(P)(+) transhydrogenase (AB-specific) (NCBI) compare
Rru_A3749 -0.5 -2.0 hypothetical protein (NCBI) compare
Rru_A1411 -0.5 -2.5 Protein of unknown function DUF162 (NCBI) compare


Specific Phenotypes

None in this experiment

For Rhodospirillum rubrum S1H in carbon source experiments

For carbon source Sodium succinate dibasic hexahydrate across organisms