Experiment set7IT083 for Rhodospirillum rubrum S1H

Compare to:

Succinate carbon source_noKan

200 most important genes:

  gene name fitness t score description  
Rru_A3425 -5.5 -4.3 Phosphoribosylanthranilate isomerase (NCBI) compare
Rru_A1189 -5.2 -19.5 3-isopropylmalate dehydratase large subunit region (NCBI) compare
Rru_A3751 -5.1 -15.8 Argininosuccinate synthase (NCBI) compare
Rru_A1895 -5.1 -2.2 Glutamine amidotransferase of anthranilate synthase (NCBI) compare
Rru_A3428 -5.0 -17.6 Tryptophan synthase (NCBI) compare
Rru_A1191 -5.0 -10.6 3-isopropylmalate dehydrogenase (NCBI) compare
Rru_A3162 -5.0 -19.8 Prephenate dehydratase (NCBI) compare
Rru_A2772 -4.9 -3.4 ATP phosphoribosyltransferase (NCBI) compare
Rru_A0467 -4.9 -21.5 Acetolactate synthase, large subunit, biosynthetic type (NCBI) compare
Rru_A2885 -4.9 -18.3 Carbamoyl-phosphate synthase, small subunit (NCBI) compare
Rru_A1897 -4.8 -8.1 Indole-3-glycerol-phosphate synthase (NCBI) compare
Rru_A3267 -4.7 -8.8 Methionine biosynthesis MetW (NCBI) compare
Rru_A2549 -4.7 -10.1 HAD-superfamily hydrolase subfamily IIB (NCBI) compare
Rru_A2886 -4.7 -24.1 Carbamoyl-phosphate synthase, large subunit, glutamine-dependent (NCBI) compare
Rru_A1239 -4.7 -5.4 Glutamate 5-kinase, ProB-related (NCBI) compare
Rru_A3276 -4.6 -5.8 Ornithine carbamoyltransferase (NCBI) compare
Rru_A3341 -4.6 -3.1 Acetylglutamate kinase (NCBI) compare
Rru_A3266 -4.6 -15.9 Homoserine O-acetyltransferase (NCBI) compare
Rru_A0469 -4.4 -18.7 Ketol-acid reductoisomerase (NCBI) compare
Rru_A1896 -4.4 -8.4 Anthranilate phosphoribosyl transferase (NCBI) compare
Rru_A1786 -4.4 -21.2 Dihydroxy-acid dehydratase (NCBI) compare
Rru_A3264 -4.4 -6.0 Histidinol-phosphate aminotransferase (NCBI) compare
Rru_A3594 -4.3 -2.9 Histidine biosynthesis protein HisF (NCBI) compare
Rru_A1928 -4.3 -15.6 Yeast 2-isopropylmalate synthase (NCBI) compare
Rru_A1190 -4.3 -2.6 3-isopropylmalate dehydratase small subunit region (NCBI) compare
Rru_A3191 -4.2 -16.8 Dihydroorotase multifunctional complex type (NCBI) compare
Rru_A0468 -4.2 -4.1 Acetolactate synthase, small subunit (NCBI) compare
Rru_A1530 -4.0 -22.2 5,10-methylenetetrahydrofolate reductase (NCBI) compare
Rru_A1105 -3.9 -6.0 tRNA synthetase, class II (G, H, P and S) (NCBI) compare
Rru_A2936 -3.8 -10.8 Dihydroorotase multifunctional complex type (NCBI) compare
Rru_A2507 -3.6 -17.5 Orotate phosphoribosyl transferase (NCBI) compare
Rru_A0397 -3.6 -6.5 Argininosuccinate lyase (NCBI) compare
Rru_A3190 -3.6 -3.4 Aspartate carbamoyltransferase (NCBI) compare
Rru_A3214 -3.6 -16.2 O-succinylhomoserine sulfhydrylase (NCBI) compare
Rru_A3427 -3.6 -14.1 Tryptophan synthase, beta chain (NCBI) compare
Rru_A2421 -3.4 -7.2 N-acetyl-gamma-glutamyl-phosphate reductase (NCBI) compare
Rru_A2771 -3.4 -5.9 Histidinol dehydrogenase (NCBI) compare
Rru_A0394 -3.2 -5.7 Amino-acid N-acetyltransferase (NCBI) compare
Rru_A3165 -3.2 -5.2 Histidinol-phosphate phosphatase, putative, inositol monophosphatase (NCBI) compare
Rru_A3277 -3.1 -5.9 Acetylornithine and succinylornithine aminotransferase (NCBI) compare
Rru_A0514 -3.0 -7.5 Dihydroorotate dehydrogenase 2 (NCBI) compare
Rru_A1084 -3.0 -6.3 5-formyltetrahydrofolate cyclo-ligase (NCBI) compare
Rru_A3596 -3.0 -6.2 Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit (NCBI) compare
Rru_A3424 -2.6 -3.2 Orotidine-5'-phosphate decarboxylase (NCBI) compare
Rru_A1051 -2.4 -2.7 Phosphoribosylaminoimidazole carboxylase, ATPase subunit (NCBI) compare
Rru_B0050 -2.3 -2.7 dTDP-glucose 4,6-dehydratase (NCBI) compare
Rru_A1827 -2.3 -6.6 Glycine hydroxymethyltransferase (NCBI) compare
Rru_A1432 -2.3 -12.6 Nicotinate-nucleotide pyrophosphorylase (NCBI) compare
Rru_A1620 -2.1 -2.9 hypothetical protein (NCBI) compare
Rru_A0058 -2.1 -3.0 Dihydrokaempferol 4-reductase (NCBI) compare
Rru_A0963 -2.0 -5.7 MifU-like protein, Fe-S cluster formation (NCBI) compare
Rru_A3380 -1.9 -1.8 hypothetical protein (NCBI) compare
Rru_A2167 -1.8 -4.6 Phosphoribosylformylglycinamidine cyclo-ligase (NCBI) compare
Rru_A1434 -1.8 -11.8 Quinolinate synthetase A (NCBI) compare
Rru_A0454 -1.7 -3.4 Leucyl aminopeptidase (NCBI) compare
Rru_A2847 -1.7 -3.3 Transcriptional regulators, TraR/DksA family (NCBI) compare
Rru_A1865 -1.7 -7.6 Dihydrodipicolinate synthase subfamily (NCBI) compare
Rru_A0265 -1.5 -4.3 Electron-transferring-flavoproteindehydrogenase (NCBI) compare
Rru_A1529 -1.5 -5.3 Transcriptional Regulator, ArsR family (NCBI) compare
Rru_A3642 -1.5 -2.6 Negative regulator of class I heat shock protein (NCBI) compare
Rru_A1841 -1.4 -1.6 Flavin reductase-like, FMN-binding (NCBI) compare
Rru_A0574 -1.4 -2.5 Carboxylyase-related protein (NCBI) compare
Rru_A0073 -1.3 -5.8 ribosomal subunit interface protein, putative (NCBI) compare
Rru_A0010 -1.3 -3.5 Sigma-54 (RpoN) (NCBI) compare
Rru_A1435 -1.3 -4.0 Two Component, Sigma54 Specific, Transcriptional Regulator, Fis family (NCBI) compare
Rru_A1854 -1.3 -4.6 Pyridoxal phosphate biosynthetic protein PdxJ (NCBI) compare
Rru_A0432 -1.3 -2.5 4-hydroxythreonine-4-phosphate dehydrogenase (NCBI) compare
Rru_A2370 -1.2 -2.1 GCN5-related N-acetyltransferase (NCBI) compare
Rru_A1436 -1.1 -4.0 Histidine Kinase (NCBI) compare
Rru_A1437 -1.1 -4.7 Sodium:dicarboxylate symporter (NCBI) compare
Rru_A2411 -1.1 -5.9 Aminotransferase, class I and II (NCBI) compare
Rru_A3801 -1.1 -1.9 Enoyl-CoA hydratase/isomerase (NCBI) compare
Rru_A3202 -1.1 -5.0 DNA topoisomerase (NCBI) compare
Rru_A3571 -1.1 -4.5 Glycerol-3-phosphate dehydrogenase (NAD(P)+) (NCBI) compare
Rru_A1208 -1.1 -4.3 AFG1-like ATPase (NCBI) compare
Rru_A3773 -1.1 -2.3 CBS domain protein (NCBI) compare
Rru_A2100 -1.1 -6.4 Protein of unknown function DUF81 (NCBI) compare
Rru_A1433 -1.1 -5.1 L-aspartate oxidase (NCBI) compare
Rru_A3533 -1.1 -7.6 hypothetical protein (NCBI) compare
Rru_A0225 -1.1 -3.8 Metal dependent phosphohydrolase, HD region (NCBI) compare
Rru_A2951 -1.1 -2.3 hypothetical protein (NCBI) compare
Rru_A2085 -1.1 -1.9 Nitrogen regulatory protein P-II (GlnB, GlnK) (NCBI) compare
Rru_A3748 -1.0 -3.9 hypothetical protein (NCBI) compare
Rru_A1138 -1.0 -4.4 ABC transporter component (NCBI) compare
Rru_A1308 -1.0 -7.5 Acyl-CoA dehydrogenase (NCBI) compare
Rru_A3010 -1.0 -4.9 Transcriptional Regulator, DeoR family (NCBI) compare
Rru_A1669 -1.0 -2.9 Transcriptional Regulator, MerR family (NCBI) compare
Rru_A0348 -1.0 -2.4 CRISPR-associated protein, Cas2 (NCBI) compare
Rru_A1537 -1.0 -1.8 hypothetical protein (NCBI) compare
Rru_A0644 -1.0 -3.0 hypothetical protein (NCBI) compare
Rru_A0404 -0.9 -7.8 Amidophosphoribosyl transferase (NCBI) compare
Rru_A0484 -0.9 -3.0 hypothetical protein (NCBI) compare
Rru_A2547 -0.9 -7.3 N-formylglutamate amidohydrolase (NCBI) compare
Rru_A1775 -0.9 -1.5 chromosome segregation and condensation protein ScpA (NCBI) compare
Rru_A3378 -0.9 -3.9 hypothetical protein (NCBI) compare
Rru_A1137 -0.9 -7.4 transport system permease protein (NCBI) compare
Rru_A2994 -0.9 -3.3 hypothetical protein (NCBI) compare
Rru_A0412 -0.9 -2.3 hypothetical protein (NCBI) compare
Rru_A0637 -0.9 -2.1 hypothetical protein (NCBI) compare
Rru_A1019 -0.9 -3.1 FAD dependent oxidoreductase (NCBI) compare
Rru_A2865 -0.9 -4.7 Peptidase M24 (NCBI) compare
Rru_A0908 -0.9 -1.2 microcompartments protein (NCBI) compare
Rru_A0006 -0.9 -2.7 Plasmid maintenance system antidote protein (NCBI) compare
Rru_A1309 -0.9 -4.9 acetoacetyl-CoA reductase (NCBI) compare
Rru_A2887 -0.9 -2.3 GreA/GreB family elongation factor (NCBI) compare
Rru_A0398 -0.9 -3.8 Thiol-disulfide isomerase and thioredoxins-like (NCBI) compare
Rru_A0155 -0.9 -1.9 Transcriptional Regulator, TetR family (NCBI) compare
Rru_A1136 -0.9 -6.8 Periplasmic binding protein (NCBI) compare
Rru_A1788 -0.9 -1.3 Response regulator receiver domain protein (CheY) (NCBI) compare
Rru_A0596 -0.8 -2.0 Fructose-bisphosphate aldolase, class II, Calvin cycle subtype (NCBI) compare
Rru_A3393 -0.8 -3.2 Penicillin-binding protein 1A (NCBI) compare
Rru_A1527 -0.8 -3.9 ABC transporter component (NCBI) compare
Rru_A1048 -0.8 -2.9 Protein of unknown function DUF465 (NCBI) compare
Rru_A3275 -0.8 -2.6 Hsp33 protein (NCBI) compare
Rru_A2574 -0.8 -1.3 Transcriptional Regulator, BadM/Rrf2 family (NCBI) compare
Rru_A3782 -0.8 -5.2 Ribosome-binding factor A (NCBI) compare
Rru_A0683 -0.8 -0.6 3-deoxy-7-phosphoheptulonate synthase (NCBI) compare
Rru_A1085 -0.8 -2.2 Metallophosphoesterase (NCBI) compare
Rru_A0341 -0.7 -2.2 hypothetical protein (NCBI) compare
Rru_A2530 -0.7 -4.6 hypothetical protein (NCBI) compare
Rru_A3783 -0.7 -6.0 tRNA pseudouridine synthase B (NCBI) compare
Rru_A2760 -0.7 -0.3 hypothetical protein (NCBI) compare
Rru_A3599 -0.7 -1.4 20S proteasome, A and B subunits (NCBI) compare
Rru_A3254 -0.7 -2.2 ABC transporter component (NCBI) compare
Rru_A0686 -0.7 -0.7 Transcriptional Regulator, LysR family (NCBI) compare
Rru_A2939 -0.7 -2.1 hypothetical protein (NCBI) compare
Rru_A2798 -0.6 -1.5 hypothetical protein (NCBI) compare
Rru_A2800 -0.6 -2.4 hypothetical protein (NCBI) compare
Rru_A2729 -0.6 -2.1 hypothetical protein (NCBI) compare
Rru_A3268 -0.6 -2.5 hypothetical protein (NCBI) compare
Rru_A2244 -0.6 -5.3 Glycogen/starch/alpha-glucan phosphorylase (NCBI) compare
Rru_A2656 -0.6 -1.7 ATP12 ATPase (NCBI) compare
Rru_A1814 -0.6 -2.5 Carbon monoxide dehydrogenase subunit G (NCBI) compare
Rru_A2268 -0.6 -1.4 Nitrogen fixation protein NifW (NCBI) compare
Rru_A3677 -0.6 -2.3 Tripartite ATP-independent periplasmic transporter, DctQ component (NCBI) compare
Rru_A1047 -0.6 -4.2 6-phosphofructokinase (NCBI) compare
Rru_A1593 -0.6 -3.8 Peptidase M50, putative membrane-associated zinc metallopeptidase (NCBI) compare
Rru_A3627 -0.6 -3.1 Cobyrinic acid a,c-diamide synthase (NCBI) compare
Rru_A0537 -0.6 -2.3 Protein of unknown function DUF955 (NCBI) compare
Rru_B0025 -0.6 -2.7 hypothetical protein (NCBI) compare
Rru_A0876 -0.6 -0.9 hypothetical protein (NCBI) compare
Rru_A3800 -0.6 -1.5 hypothetical protein (NCBI) compare
Rru_A2181 -0.6 -4.8 NAD(P) transhydrogenase, beta subunit (NCBI) compare
Rru_A3548 -0.6 -4.7 Magnesium-protoporphyrin IX monomethyl ester anaerobic oxidative cyclase (NCBI) compare
Rru_A1891 -0.6 -4.8 Anthranilate synthase component I (NCBI) compare
Rru_A1607 -0.6 -4.6 4-alpha-glucanotransferase (NCBI) compare
Rru_A2478 -0.6 -4.1 ArgK protein (NCBI) compare
Rru_A3502 -0.6 -0.7 hypothetical protein (NCBI) compare
Rru_A1454 -0.6 -1.3 Phage Tail Collar (NCBI) compare
Rru_A3766 -0.6 -3.1 Transcriptional Regulator, MucR family (NCBI) compare
Rru_A0643 -0.6 -3.1 Protein of unknown function DUF152 (NCBI) compare
Rru_A0777 -0.6 -2.1 D-lactate dehydrogenase (cytochrome) (NCBI) compare
Rru_A3369 -0.6 -1.2 hypothetical protein (NCBI) compare
Rru_A0657 -0.6 -1.9 Lysine exporter protein (LYSE/YGGA) (NCBI) compare
Rru_A0296 -0.5 -2.7 hypothetical protein (NCBI) compare
Rru_A0448 -0.5 -3.5 Protein of unknown function DUF52 (NCBI) compare
Rru_A0647 -0.5 -1.2 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit (NCBI) compare
Rru_A0801 -0.5 -1.9 Binding-protein-dependent transport systems inner membrane component (NCBI) compare
Rru_A3261 -0.5 -1.6 hypothetical protein (NCBI) compare
Rru_A1256 -0.5 -1.3 hypothetical protein (NCBI) compare
Rru_A1845 -0.5 -2.4 Arginyltransferase (NCBI) compare
Rru_A0180 -0.5 -1.2 hypothetical protein (NCBI) compare
Rru_A1310 -0.5 -2.4 Acetyl-CoA C-acyltransferase (NCBI) compare
Rru_A2115 -0.5 -3.5 Phosphoglucomutase/phosphomannomutase (NCBI) compare
Rru_A3255 -0.5 -1.9 Protein of unknown function DUF214 (NCBI) compare
Rru_A1834 -0.5 -3.0 Enoyl-CoA hydratase/isomerase (NCBI) compare
Rru_A3271 -0.5 -3.3 glutathione S-transferase family protein (NCBI) compare
Rru_A1218 -0.5 -1.1 phage shock protein A, PspA (NCBI) compare
Rru_A3547 -0.5 -2.0 hypothetical protein (NCBI) compare
Rru_A2609 -0.5 -0.7 hypothetical protein (NCBI) compare
Rru_A2224 -0.5 -0.9 Transcriptional Regulator, MarR family (NCBI) compare
Rru_A0159 -0.5 -1.5 Exodeoxyribonuclease VII (NCBI) compare
Rru_A0661 -0.5 -1.9 Hly-III related proteins (NCBI) compare
Rru_A1692 -0.5 -2.9 S-adenosylmethionine decarboxylase related (NCBI) compare
Rru_A3139 -0.5 -2.6 Transcriptional Regulator, GntR family (NCBI) compare
Rru_A1691 -0.5 -2.9 Spermine synthase (NCBI) compare
Rru_A2163 -0.5 -1.0 conserved hypothetical protein RP631 (NCBI) compare
Rru_A1678 -0.5 -1.5 Nitrogen Metabolism Transcriptional Regulator, NtrC, Fis Family (NCBI) compare
Rru_A2410 -0.5 -1.7 Homoserine dehydrogenase (NCBI) compare
Rru_A3208 -0.5 -2.8 Protein of unknown function DUF29 (NCBI) compare
Rru_A1060 -0.5 -1.8 Transcriptional Regulator, LysR family (NCBI) compare
Rru_A0424 -0.5 -1.2 hypothetical protein (NCBI) compare
Rru_A1916 -0.5 -1.7 Ferredoxin (NCBI) compare
Rru_A2510 -0.5 -0.5 hypothetical protein (NCBI) compare
Rru_A1014 -0.5 -2.2 hypothetical protein (NCBI) compare
Rru_A1973 -0.5 -2.6 Transcriptional Regulator, LacI family (NCBI) compare
Rru_A1870 -0.5 -1.8 CinA-like (NCBI) compare
Rru_A2383 -0.4 -2.1 ABC transporter component (NCBI) compare
Rru_A2562 -0.4 -2.5 CheW protein (NCBI) compare
Rru_A2512 -0.4 -2.1 3-oxoacyl-(acyl-carrier-protein) reductase (NCBI) compare
Rru_A1444 -0.4 -3.4 Ribonucleoside-diphosphate reductase (NCBI) compare
Rru_A0496 -0.4 -1.5 Cyclic nucleotide-binding domain (cNMP-BD) protein (NCBI) compare
Rru_A0534 -0.4 -2.2 hypothetical protein (NCBI) compare
Rru_A2246 -0.4 -3.8 Glucose-1-phosphate adenylyltransferase (NCBI) compare
Rru_A2137 -0.4 -2.3 Protein of unknown function DUF847 (NCBI) compare
Rru_A1768 -0.4 -1.2 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (NCBI) compare
Rru_A3019 -0.4 -0.8 hypothetical protein (NCBI) compare
Rru_A0679 -0.4 -2.3 Transcriptional Regulator, TetR family (NCBI) compare
Rru_A2429 -0.4 -1.2 Plasmid maintenance system killer (NCBI) compare
Rru_A1007 -0.4 -1.9 Nitrogenase-associated protein (NCBI) compare


Specific Phenotypes

None in this experiment

For Rhodospirillum rubrum S1H in carbon source experiments

For carbon source Sodium succinate dibasic hexahydrate across organisms