Experiment set7IT076 for Phaeobacter inhibens DSM 17395

Compare to:

marine broth with Fusidic acid sodium salt 0.0002 mg/ml

200 most detrimental genes:

  gene name fitness t score description  
PGA1_c23720 +3.7 14.9 glutathione reductase Gor compare
PGA1_c04510 +3.5 26.7 Protein of unknown function (DUF3307). compare
PGA1_c14530 +1.5 3.0 transcriptional regulator, TetR family compare
PGA1_c02850 +1.5 4.1 peptidase S49-like protein compare
PGA1_c24220 +1.5 5.4 ornithine carbamoyltransferase ArgF compare
PGA1_c23710 +1.5 6.3 putative protein HflK compare
PGA1_c36020 +1.5 2.4 putative 3'-5'-exonuclease compare
PGA1_c31780 +1.4 4.3 DNA polymerase I compare
PGA1_c35170 +1.3 3.7 DNA polymerase III subunit epsilon compare
PGA1_c24230 +1.3 8.6 acetylornithine aminotransferase ArgD compare
PGA1_c21800 +1.2 7.5 putative transporter compare
PGA1_c13580 +1.2 7.4 secretion protein, HlyD family compare
PGA1_c05420 +1.2 3.0 glucokinase (EC 2.7.1.2) (from data) compare
PGA1_c04960 +1.1 8.2 putative non-specific ribonucleoside hydrolase compare
PGA1_c08780 +1.1 3.9 hypothetical protein compare
PGA1_c04450 +1.1 9.2 glutathione import ATP-binding protein GsiA compare
PGA1_c04420 +1.1 9.1 putative glutathione transport system permease protein GsiD compare
PGA1_c09100 +1.1 7.3 putative thiamine biosynthesis oxidoreductase ThiO compare
PGA1_c02950 +1.1 7.2 RNA methyltransferase-like protein conserved
PGA1_c04440 +1.1 9.3 putative extracellular solute-binding protein compare
PGA1_c13840 +1.1 6.1 putative transcriptional regulator, AraC family compare
PGA1_c09070 +1.1 8.0 thiazole biosynthesis protein ThiG compare
PGA1_c13370 +1.1 2.1 Methionine synthase component, methyltransferase domain (EC:2.1.1.13) (from data) compare
PGA1_c11710 +1.0 6.1 transcriptional regulator, LysR family compare
PGA1_c09050 +1.0 6.8 thiamine-phosphate pyrophosphorylase ThiE compare
PGA1_c09110 +1.0 8.5 thiamine biosynthesis protein ThiC compare
PGA1_c19870 +1.0 4.6 hypothetical protein compare
PGA1_c03330 +1.0 4.9 tetratricopeptide repeat-containing protein compare
PGA1_c04430 +1.0 8.0 putative peptide permease protein compare
PGA1_c02450 +1.0 8.4 putative outer membrane efflux protein compare
PGA1_c08600 +1.0 8.1 diguanylate cyclase (GGDEF) domain-containing protein compare
PGA1_c29830 +1.0 6.8 3-isopropylmalate dehydrogenase LeuB compare
PGA1_c29780 +0.9 6.4 3-isopropylmalate dehydratase large subunit compare
PGA1_c02050 +0.9 4.1 acetylglutamate kinase ArgB compare
PGA1_c31910 +0.9 5.7 YGGT family. compare
PGA1_c33600 +0.9 2.3 hypothetical protein compare
PGA1_c23690 +0.9 6.1 protease do compare
PGA1_c02440 +0.9 8.0 putative ATP-binding/permease fusion ABC transporter compare
PGA1_c02460 +0.9 8.2 hypothetical protein compare
PGA1_c17050 +0.9 3.4 N-acetyl-gamma-glutamyl-phosphate reductase ArgC compare
PGA1_c08590 +0.9 7.1 heme NO binding domain-containing protein compare
PGA1_65p00180 +0.9 3.6 putative sugar transferase compare
PGA1_c02430 +0.9 6.4 type I secretion membrane fusion protein, HlyD family compare
PGA1_c09040 +0.9 6.5 putative adenylyltransferase ThiF compare
PGA1_c24560 +0.8 5.9 carbamoyl-phosphate synthase large chain compare
PGA1_c15200 +0.8 2.5 ATP-dependent reduction of co(II)balamin (RamA-like) (EC:2.1.1.13) (from data) compare
PGA1_c06420 +0.8 4.5 acetyltransferase domain-containing protein compare
PGA1_c34770 +0.8 5.6 Uncharacterized protein conserved in bacteria compare
PGA1_c31580 +0.8 4.0 putative HTH-type transcriptional regulator, TetR family conserved
PGA1_c31270 +0.8 7.3 putative glycosyltransferase / polysaccharide deacetylase compare
PGA1_c11400 +0.8 3.9 ferric uptake regulation protein Fur compare
PGA1_c34890 +0.8 6.2 putative histidine-containing phosphotransfer protein compare
PGA1_c06670 +0.8 3.1 carbamoyl-phosphate synthase small chain compare
PGA1_c14540 +0.7 2.8 putative polyphosphate kinase 2 compare
PGA1_c09030 +0.7 5.1 phosphomethylpyrimidine kinase ThiD compare
PGA1_c02020 +0.7 2.3 Predicted metal-binding protein compare
PGA1_c23700 +0.7 2.6 protein HflC compare
PGA1_c33190 +0.7 3.6 putative anti-sigma-B factor antagonist compare
PGA1_262p00660 +0.7 1.9 Predicted periplasmic protein compare
PGA1_c34880 +0.7 6.1 putative response regulator compare
PGA1_c31260 +0.7 6.6 Protein of unknown function (DUF3131). compare
PGA1_c29790 +0.7 3.8 3-isopropylmalate dehydratase small subunit compare
PGA1_c31230 +0.7 1.3 hypothetical protein compare
PGA1_c09090 +0.7 2.5 thiamine biosynthesis protein ThiS compare
PGA1_c34150 +0.7 1.5 exodeoxyribonuclease VII, small subunit compare
PGA1_c15260 +0.7 2.1 protein recA (recombinase A) compare
PGA1_c09290 +0.7 3.4 WGR domain. compare
PGA1_c13340 +0.7 2.9 Accessory protein for co(II)balamin reduction (DUF1638) (EC:2.1.1.13) (from data) compare
PGA1_c35370 +0.7 4.9 sensor histidine kinase RegB compare
PGA1_c18820 +0.6 3.2 Uncharacterized secreted protein compare
PGA1_c30470 +0.6 2.9 mandelate racemase / muconate lactonizing enzyme compare
PGA1_c18480 +0.6 5.8 hypothetical protein compare
PGA1_c06020 +0.6 3.1 thioesterase domain-containing protein compare
PGA1_c26850 +0.6 2.2 Predicted metal-binding protein compare
PGA1_c19200 +0.6 1.4 Predicted Fe-S protein compare
PGA1_c23770 +0.6 4.6 L-serine dehydratase TdcG compare
PGA1_c26630 +0.6 2.8 deoxyuridine 5'-triphosphate nucleotidohydrolase Dut compare
PGA1_c15040 +0.6 3.4 Uncharacterized conserved protein compare
PGA1_c35260 +0.6 1.9 ATP-dependent protease HslV compare
PGA1_262p01490 +0.6 1.6 putative sarcosine oxidase, gamma subunit compare
PGA1_c25130 +0.6 2.5 Methylase involved in ubiquinone/menaquinone biosynthesis compare
PGA1_c15750 +0.6 3.3 phosphate import ATP-binding protein PstB compare
PGA1_c10730 +0.6 1.5 ribose-5-phosphate isomerase B compare
PGA1_c18490 +0.6 5.1 Predicted ATPase compare
PGA1_c13750 +0.6 3.4 phosphopantetheine binding protein compare
PGA1_c17350 +0.6 3.5 3-hydroxyisobutyryl-CoA hydrolase (EC 3.1.2.4) (from data) compare
PGA1_c11810 +0.6 1.5 hypothetical protein compare
PGA1_c29620 +0.6 1.7 putative CDP-diacylglycerol--serine O-phosphatidyltransferase compare
PGA1_c01080 +0.5 2.3 Uncharacterized conserved protein compare
PGA1_c03080 +0.5 2.9 molybdenum cofactor biosynthesis protein B compare
PGA1_c01830 +0.5 2.4 Uncharacterized conserved small protein compare
PGA1_c11070 +0.5 2.0 exodeoxyribonuclease III compare
PGA1_c09180 +0.5 2.2 Protein of unknown function (DUF2478). compare
PGA1_c32710 +0.5 1.8 Protein of unknown function (DUF3775). compare
PGA1_c15280 +0.5 2.3 Uncharacterized conserved protein compare
PGA1_c09580 +0.5 1.2 antibiotic biosynthesis monooxygenase-like protein compare
PGA1_c06170 +0.5 2.3 hypothetical protein compare
PGA1_c12550 +0.5 1.8 hypothetical protein compare
PGA1_262p01290 +0.5 2.7 transcriptional regulator, AraC family compare
PGA1_c34450 +0.5 3.5 putrescine transport system permease protein PotI compare
PGA1_c02900 +0.5 1.4 putative molybdopterin-converting factor subunit 1 compare
PGA1_262p01420 +0.5 1.6 Protein of unknown function (DUF3726). compare
PGA1_c32660 +0.5 2.1 WGR domain. compare
PGA1_262p00610 +0.5 0.8 metallophosphoesterase compare
PGA1_262p01165 +0.5 1.5 hypothetical protein compare
PGA1_262p00250 +0.5 1.1 ferritin-like protein compare
PGA1_c16360 +0.5 1.2 putative transriptional regulator, AsnC family compare
PGA1_78p00540 +0.5 1.4 hypothetical protein compare
PGA1_262p00950 +0.5 2.1 thioesterase superfamily protein TdaD compare
PGA1_c15920 +0.5 2.0 putative branched-chain amino acid transport ATP-binding protein compare
PGA1_c15770 +0.5 2.6 putative phosphate transport system permease protein PstC compare
PGA1_c17950 +0.5 3.0 Cytochrome B561 compare
PGA1_c09900 +0.5 3.1 malate synthase GlcB compare
PGA1_c10090 +0.5 2.6 YeeE/YedE family (DUF395). compare
PGA1_c22370 +0.4 2.4 hypothetical protein compare
PGA1_c29320 +0.4 2.2 putative endoribonuclease L-PSP compare
PGA1_c29000 +0.4 2.2 inner membrane lipoprotein compare
PGA1_78p00160 +0.4 1.1 putative sugar-binding periplasmic protein compare
PGA1_c12070 +0.4 1.1 hypothetical protein compare
PGA1_c08550 +0.4 1.6 Protein of unknown function (DUF3572). compare
PGA1_c17810 +0.4 1.8 putative gene transfer agent protein compare
PGA1_c17280 +0.4 2.4 cystathionine beta-synthase-like protein compare
PGA1_c04310 +0.4 0.9 Protein of unknown function (DUF1045). compare
PGA1_c13530 +0.4 2.0 hypothetical protein compare
PGA1_c11120 +0.4 2.4 putative deoxyguanosinetriphosphate triphosphohydrolase compare
PGA1_c13110 +0.4 1.7 putative nitrilotriacetate monooxygenase component B compare
PGA1_c19100 +0.4 1.3 hypothetical protein compare
PGA1_c13350 +0.4 1.3 Methionine synthase component, B12 binding and B12-binding cap domains (EC:2.1.1.13) (from data) compare
PGA1_65p00430 +0.4 2.0 putative glycosyl transferase compare
PGA1_c31880 +0.4 3.8 signal transduction histidine kinase compare
PGA1_c35920 +0.4 1.1 thiamine kinase ThiK-like protein compare
PGA1_c09470 +0.4 2.6 putative ATP-binding protein compare
PGA1_262p00710 +0.4 1.2 serine/threonine-protein kinase RsbT-like protein compare
PGA1_c29560 +0.4 2.3 hypothetical protein compare
PGA1_c14800 +0.4 1.6 nitrogen regulation protein NtrY compare
PGA1_c13620 +0.4 2.1 hypothetical protein compare
PGA1_c19780 +0.4 1.8 clan AA aspartic protease, TIGR02281 family compare
PGA1_c16460 +0.4 2.2 2-isopropylmalate synthase/homocitrate synthase-like protein compare
PGA1_c16780 +0.4 1.9 Uncharacterized conserved protein compare
PGA1_c05650 +0.4 1.0 tRNA pseudouridine synthase A compare
PGA1_c23210 +0.4 1.4 hypothetical protein compare
PGA1_c10910 +0.4 2.3 dihydroorotase PyrC compare
PGA1_c20340 +0.4 1.2 Uncharacterized protein conserved in bacteria compare
PGA1_c25260 +0.4 2.1 PA14 domain. compare
PGA1_262p01820 +0.4 1.8 Protein of unknown function (DUF3726). compare
PGA1_c05400 +0.4 2.6 putative glycosyl transferase, family 2 compare
PGA1_c16920 +0.4 1.4 molybdenum cofactor biosynthesis protein C compare
PGA1_c33040 +0.4 2.4 aldehyde dehydrogenase compare
PGA1_c34440 +0.4 2.3 putrescine transport system permease protein PotH compare
PGA1_262p00730 +0.4 1.3 putative signal transduction histidine kinase compare
PGA1_262p00450 +0.4 1.3 glucose transporter, ATPase component (from data) compare
PGA1_c08890 +0.4 1.9 putative capsule polysaccharide export outer membrane protein compare
PGA1_c29290 +0.4 1.9 putative pterin 4 alpha carbinolamine dehydratase compare
PGA1_c03770 +0.4 1.5 hypothetical protein compare
PGA1_c14190 +0.4 2.5 putative transcriptional regulator, AraC family compare
PGA1_c26890 +0.4 1.7 putative endoribonuclease compare
PGA1_c31960 +0.4 2.5 conserved hypothetical integral membrane protein compare
PGA1_c28460 +0.4 2.6 putative metallopeptidase, family M24 compare
PGA1_c06120 +0.4 2.6 Flp pilus assembly protein, ATPase CpaE compare
PGA1_c32670 +0.4 1.8 putative phosphoglycerate mutase family protein compare
PGA1_262p00320 +0.4 1.6 ABC transporter, inner membrane component compare
PGA1_c04500 +0.4 2.8 transcriptional regulator, AsnC family compare
PGA1_c24410 +0.4 1.6 hypothetical protein compare
PGA1_c27040 +0.4 2.1 Predicted permease compare
PGA1_c05070 +0.4 2.3 putative pyridoxal-phosphate-dependent aminotransferase compare
PGA1_c19640 +0.3 1.8 transcriptional regulator, containing response regulator domain compare
PGA1_65p00350 +0.3 2.3 hemolysin-like protein compare
PGA1_c27900 +0.3 1.6 ligand-binding UTRA domain-containing protein compare
PGA1_c26480 +0.3 1.7 Protein involved in catabolism of external DNA compare
PGA1_c07620 +0.3 2.9 Type IV pilus biogenesis. compare
PGA1_c24820 +0.3 1.7 phenazine biosynthesis protein compare
PGA1_c20530 +0.3 1.5 putative transcriptional regulator compare
PGA1_c25960 +0.3 1.8 putative biopolymer transport protein compare
PGA1_c05300 +0.3 2.2 putative glycosyl transferase compare
PGA1_c33170 +0.3 1.4 putative sensor protein compare
PGA1_78p00250 +0.3 0.8 putative HTH-type transcriptional regulator compare
PGA1_c04110 +0.3 2.2 putative fatty acid oxidation complex subunit alpha compare
PGA1_c05530 +0.3 1.7 putative allantoin catabolism protein compare
PGA1_c06940 +0.3 2.8 putative adenosylcobalamin(B12)-dependent ribonucleotide reductases compare
PGA1_c35240 +0.3 2.4 ATP-dependent hsl protease ATP-binding subunit HslU compare
PGA1_c34430 +0.3 2.4 putrescine transport ATP-binding protein PotG compare
PGA1_c28910 +0.3 1.8 carboxymuconolactone decarboxylase-like protein compare
PGA1_c17990 +0.3 1.8 D-malate dehydrogenase compare
PGA1_c11830 +0.3 1.3 hypothetical protein compare
PGA1_65p00240 +0.3 0.7 dTDP-glucose 4,6-dehydratase RffG compare
PGA1_c25990 +0.3 0.6 hypothetical protein compare
PGA1_c07510 +0.3 2.6 DNA/RNA helicase-like protein compare
PGA1_c11490 +0.3 2.2 pyrimidine-specific ribonucleoside hydrolase RihA compare
PGA1_262p00060 +0.3 1.0 putative glycosyl transferase compare
PGA1_c13860 +0.3 1.5 transcriptional regulator, GntR family compare
PGA1_c17590 +0.3 1.9 hypothetical protein compare
PGA1_c24800 +0.3 1.0 putative bifunctional SAT/APS kinase compare
PGA1_c29740 +0.3 1.2 hypothetical protein compare
PGA1_c19090 +0.3 1.1 Protein required for attachment to host cells compare
PGA1_c33070 +0.3 1.4 Glycosyl transferase family 11. compare
PGA1_c18850 +0.3 1.3 Antibiotic biosynthesis monooxygenase. compare
PGA1_262p00600 +0.3 1.8 Bacterial putative lipoprotein (DUF940). compare
PGA1_262p01680 +0.3 1.3 hypothetical protein compare
PGA1_c18660 +0.3 1.6 hypothetical protein compare
PGA1_c12160 +0.3 1.3 Uncharacterized protein conserved in bacteria compare


Specific Phenotypes

For 6 genes in this experiment

For stress Fusidic acid sodium salt in Phaeobacter inhibens DSM 17395

For stress Fusidic acid sodium salt across organisms