Experiment set7IT068 for Klebsiella michiganensis M5al

Compare to:

LB with Fusidic acid sodium salt 0.5 mg/ml

200 most detrimental genes:

  gene name fitness t score description  
BWI76_RS27680 +4.1 3.4 TetR family transcriptional regulator compare
BWI76_RS07465 +1.5 11.3 TetR family transcriptional regulator compare
BWI76_RS24885 +1.1 1.7 PTS galactitol transporter subunit IIB compare
BWI76_RS10745 +1.1 2.1 hypothetical protein compare
BWI76_RS16355 +1.1 3.1 electron transport complex subunit A compare
BWI76_RS12070 +1.0 2.0 hypothetical protein compare
BWI76_RS10835 +1.0 1.8 hypothetical protein compare
BWI76_RS18240 +1.0 2.7 L-arabinose ABC transporter permease AraH compare
BWI76_RS06635 +1.0 1.3 methylated-DNA--protein-cysteine methyltransferase compare
BWI76_RS01135 +1.0 3.3 lipopolysaccharide N-acetylmannosaminouronosyltransferase compare
BWI76_RS01115 +0.9 1.7 dTDP-4-amino-4,6-dideoxygalactose transaminase compare
BWI76_RS20230 +0.9 2.3 hypothetical protein compare
BWI76_RS07470 +0.9 2.7 MBL fold metallo-hydrolase compare
BWI76_RS10305 +0.9 5.8 transposase compare
BWI76_RS00180 +0.9 1.8 F0F1 ATP synthase subunit epsilon compare
BWI76_RS14435 +0.9 1.6 glutamine ABC transporter ATP-binding protein compare
BWI76_RS07865 +0.9 2.5 methylthioribulose 1-phosphate dehydratase compare
BWI76_RS18755 +0.8 1.4 adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase compare
BWI76_RS16360 +0.8 1.7 electron transport complex subunit RsxB compare
BWI76_RS16935 +0.8 1.6 shikimate dehydrogenase compare
BWI76_RS21345 +0.8 3.2 sigma-E factor regulatory protein RseB compare
BWI76_RS02725 +0.8 1.3 HxlR family transcriptional regulator compare
BWI76_RS14980 +0.8 1.8 hypothetical protein compare
BWI76_RS14110 +0.8 2.4 C-lysozyme inhibitor compare
BWI76_RS09760 +0.8 2.5 3-phosphoshikimate 1-carboxyvinyltransferase compare
BWI76_RS18605 +0.8 1.4 oxidoreductase molybdopterin-binding protein compare
BWI76_RS14065 +0.8 1.7 hypothetical protein compare
BWI76_RS21140 +0.8 1.8 molecular chaperone HscA compare
BWI76_RS19900 +0.7 2.8 FAD:protein FMN transferase compare
BWI76_RS00140 +0.7 1.1 phosphate transport system regulator PhoU compare
BWI76_RS13160 +0.7 2.2 azoreductase compare
BWI76_RS12790 +0.7 1.1 lactate dehydrogenase compare
BWI76_RS14320 +0.7 1.6 hypothetical protein compare
BWI76_RS00480 +0.7 2.5 hypothetical protein compare
BWI76_RS15290 +0.7 1.6 transcriptional regulator compare
BWI76_RS11815 +0.7 1.6 hypothetical protein compare
BWI76_RS24575 +0.7 1.6 hypothetical protein compare
BWI76_RS11820 +0.7 1.3 short-chain dehydrogenase/reductase SDR compare
BWI76_RS05570 +0.7 1.2 hypothetical protein compare
BWI76_RS05525 +0.7 2.1 glycerophosphodiester phosphodiesterase compare
BWI76_RS05515 +0.7 1.7 NADH:ubiquinone reductase (Na(+)-transporting) subunit F compare
BWI76_RS24070 +0.6 2.5 16S rRNA (uracil(1498)-N(3))-methyltransferase compare
BWI76_RS21340 +0.6 1.6 SoxR reducing system protein RseC compare
BWI76_RS17645 +0.6 1.7 hypothetical protein compare
BWI76_RS00720 +0.6 2.0 DNA-binding response regulator compare
BWI76_RS13050 +0.6 1.8 transcriptional regulator compare
BWI76_RS20750 +0.6 1.2 carboxysome structural protein EutK compare
BWI76_RS03295 +0.6 1.1 transposase compare
BWI76_RS22955 +0.6 1.6 transcriptional regulator GcvA compare
BWI76_RS01540 +0.6 1.8 thiamine biosynthesis protein ThiS compare
BWI76_RS20940 +0.6 1.9 uracil/xanthine transporter compare
BWI76_RS06465 +0.6 1.4 IclR family transcriptional regulator compare
BWI76_RS06595 +0.6 1.7 hypothetical protein compare
BWI76_RS08970 +0.6 2.0 glutamine ABC transporter permease GlnP compare
BWI76_RS07350 +0.6 1.5 alcohol dehydrogenase compare
BWI76_RS23895 +0.6 0.8 Xaa-Pro aminopeptidase compare
BWI76_RS02695 +0.6 2.1 peptidyl-prolyl cis-trans isomerase compare
BWI76_RS18770 +0.6 0.9 DNA gyrase inhibitor compare
BWI76_RS16645 +0.6 1.6 DeoR family transcriptional regulator compare
BWI76_RS15350 +0.6 1.3 hypothetical protein compare
BWI76_RS09625 +0.6 1.4 hypothetical protein compare
BWI76_RS16655 +0.6 1.2 CatA-like O-acetyltransferase compare
BWI76_RS07760 +0.6 2.2 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase compare
BWI76_RS01110 +0.6 2.0 TDP-fucosamine acetyltransferase compare
BWI76_RS01095 +0.6 1.8 UDP-N-acetyl-D-mannosamine dehydrogenase compare
BWI76_RS22470 +0.6 2.0 transporter permease compare
BWI76_RS24770 +0.6 1.9 hypothetical protein compare
BWI76_RS20900 +0.6 1.6 outer membrane protein assembly factor BamC compare
BWI76_RS18230 +0.6 1.5 trehalose-6-phosphate synthase compare
BWI76_RS05510 +0.6 2.0 NADH:ubiquinone reductase (Na(+)-transporting) subunit E compare
BWI76_RS23005 +0.6 2.2 bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase compare
BWI76_RS11675 +0.6 1.6 arginine N-succinyltransferase compare
BWI76_RS18125 +0.6 1.6 murein DD-endopeptidase MepM compare
BWI76_RS05075 +0.6 0.9 type II secretion system protein GspG compare
BWI76_RS20245 +0.6 2.4 transketolase subunit B compare
BWI76_RS14930 +0.6 2.0 hypothetical protein compare
BWI76_RS12170 +0.6 1.7 hypothetical protein compare
BWI76_RS08260 +0.6 1.8 LysR family transcriptional regulator compare
BWI76_RS19890 +0.6 1.0 alpha-ketoglutarate-dependent dioxygenase AlkB compare
BWI76_RS06815 +0.5 2.2 adenine phosphoribosyltransferase compare
BWI76_RS06335 +0.5 1.4 nucleoside-specific channel-forming protein Tsx compare
BWI76_RS12940 +0.5 2.0 AraC family transcriptional regulator compare
BWI76_RS10365 +0.5 1.7 class IV aminotransferase compare
BWI76_RS22260 +0.5 2.4 anaerobic nitric oxide reductase flavorubredoxin compare
BWI76_RS10740 +0.5 1.6 NAD(P)H:quinone oxidoreductase compare
BWI76_RS02445 +0.5 2.5 fumarate reductase subunit C compare
BWI76_RS16445 +0.5 1.5 auxiliary transporter membrane fusion protein compare
BWI76_RS10650 +0.5 1.5 PTS fructose-like transporter subunit EIIB compare
BWI76_RS02440 +0.5 2.1 fumarate reductase subunit D compare
BWI76_RS17370 +0.5 1.5 nitrate transporter NasD compare
BWI76_RS01775 +0.5 1.1 hypothetical protein compare
BWI76_RS15845 +0.5 0.8 hypothetical protein compare
BWI76_RS12985 +0.5 1.4 transcriptional regulator compare
BWI76_RS15120 +0.5 2.0 hypothetical protein compare
BWI76_RS18580 +0.5 0.7 hypothetical protein compare
BWI76_RS04060 +0.5 1.0 hypothetical protein compare
BWI76_RS26665 +0.5 1.4 DNA-binding response regulator compare
BWI76_RS14775 +0.5 0.9 creatinine amidohydrolase compare
BWI76_RS27865 +0.5 1.7 hypothetical protein compare
BWI76_RS08780 +0.5 2.2 ABC transporter compare
BWI76_RS16030 +0.5 1.5 malonate decarboxylase acyl carrier protein compare
BWI76_RS13240 +0.5 1.0 hypothetical protein compare
BWI76_RS05550 +0.5 2.3 fermentation/respiration switch protein compare
BWI76_RS15315 +0.5 1.5 DNA-binding protein compare
BWI76_RS16225 +0.5 3.2 arginine:ornithine antiporter compare
BWI76_RS08730 +0.5 1.8 histidine utilization repressor compare
BWI76_RS10910 +0.5 1.4 hypothetical protein compare
BWI76_RS13500 +0.5 2.2 TonB-dependent receptor compare
BWI76_RS12155 +0.5 2.0 hypothetical protein compare
BWI76_RS16760 +0.5 1.6 lipase compare
BWI76_RS15950 +0.5 1.4 dethiobiotin synthase compare
BWI76_RS12710 +0.5 2.0 tRNA 2-thiocytidine(32) synthetase TtcA compare
BWI76_RS16170 +0.5 2.1 amidohydrolase compare
BWI76_RS06060 +0.5 2.6 DNA-binding response regulator compare
BWI76_RS22375 +0.5 1.5 pectin acetylesterase compare
BWI76_RS10770 +0.5 1.7 pyrimidine utilization protein C compare
BWI76_RS26750 +0.5 1.9 PfkB domain-containing protein compare
BWI76_RS15340 +0.5 2.5 urea ABC transporter substrate-binding protein compare
BWI76_RS19345 +0.5 2.4 D-arabinitol 4-dehydrogenase compare
BWI76_RS01090 +0.5 2.5 UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing) compare
BWI76_RS15775 +0.5 1.6 replication protein compare
BWI76_RS08215 +0.5 1.1 glucosamine-6-phosphate deaminase compare
BWI76_RS12105 +0.5 2.0 hypothetical protein compare
BWI76_RS00745 +0.5 3.2 1,4-dihydroxy-2-naphthoate polyprenyltransferase compare
BWI76_RS06470 +0.5 1.3 hypothetical protein compare
BWI76_RS09420 +0.5 1.3 hypothetical protein compare
BWI76_RS24955 +0.5 1.2 hypothetical protein compare
BWI76_RS24790 +0.5 3.1 LysR family transcriptional regulator compare
BWI76_RS02630 +0.5 1.3 PTS ascorbate transporter subunit IIA compare
BWI76_RS14155 +0.5 1.8 transketolase compare
BWI76_RS14755 +0.5 1.2 SIS domain-containing protein compare
BWI76_RS06740 +0.5 1.2 50S ribosomal protein L36 compare
BWI76_RS16525 +0.5 1.0 cyclopropane-fatty-acyl-phospholipid synthase compare
BWI76_RS04145 +0.5 0.6 purine-nucleoside phosphorylase compare
BWI76_RS22410 +0.5 1.4 PTS lactose/cellobiose transporter subunit IIA compare
BWI76_RS07095 +0.5 1.7 ribosome-associated protein compare
BWI76_RS11700 +0.5 0.8 hypothetical protein compare
BWI76_RS18940 +0.4 1.2 imidazole glycerol phosphate synthase subunit HisH compare
BWI76_RS01080 +0.4 2.8 undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase compare
BWI76_RS21130 +0.4 1.2 Fe-S assembly protein IscX compare
BWI76_RS04805 +0.4 1.4 8-oxo-dGTP diphosphatase compare
BWI76_RS18410 +0.4 1.5 drug/metabolite exporter YedA compare
BWI76_RS03815 +0.4 1.8 hypothetical protein compare
BWI76_RS05950 +0.4 1.1 polar amino acid ABC transporter inner membrane subunit compare
BWI76_RS19835 +0.4 1.8 nucleoid-associated protein YejK compare
BWI76_RS13405 +0.4 2.6 spermidine/putrescine ABC transporter substrate-binding protein compare
BWI76_RS11190 +0.4 1.2 putative TetR/AcrR family transcriptional regulatory protein compare
BWI76_RS18550 +0.4 1.0 tRNA-Asn compare
BWI76_RS25600 +0.4 0.6 tRNA-Thr compare
BWI76_RS16520 +0.4 2.0 Bcr/CflA family multidrug efflux MFS transporter compare
BWI76_RS08835 +0.4 2.5 molybdopterin guanine dinucleotide biosynthesis protein MoaE compare
BWI76_RS09330 +0.4 1.4 baseplate assembly protein V compare
BWI76_RS04525 +0.4 1.0 4-hydroxythreonine-4-phosphate dehydrogenase PdxA compare
BWI76_RS16990 +0.4 1.3 ABC transporter ATP-binding protein compare
BWI76_RS06745 +0.4 1.1 N-acetyltransferase GCN5 compare
BWI76_RS11860 +0.4 2.3 anthranilate synthase component I compare
BWI76_RS11020 +0.4 1.8 oxidoreductase family, NAD-binding protein compare
BWI76_RS15235 +0.4 1.1 hypothetical protein compare
BWI76_RS25485 +0.4 0.9 septum formation protein Maf compare
BWI76_RS02580 +0.4 0.8 23S rRNA (guanosine(2251)-2'-O)-methyltransferase compare
BWI76_RS09080 +0.4 1.2 molybdopterin-synthase adenylyltransferase MoeB compare
BWI76_RS04090 +0.4 2.3 ribosomal-protein-alanine N-acetyltransferase RimI compare
BWI76_RS08855 +0.4 1.9 endonuclease/exonuclease/phosphatase compare
BWI76_RS15410 +0.4 1.7 N-acetyltransferase compare
BWI76_RS06340 +0.4 0.8 hypothetical protein compare
BWI76_RS20210 +0.4 1.7 5'-deoxynucleotidase compare
BWI76_RS13320 +0.4 1.2 putative LpxA-like enzyme compare
BWI76_RS14870 +0.4 1.0 hypothetical protein compare
BWI76_RS04275 +0.4 1.6 molybdopterin adenylyltransferase compare
BWI76_RS11200 +0.4 1.6 transpeptidase compare
BWI76_RS09240 +0.4 1.4 phosphoadenosine phosphosulfate reductase compare
BWI76_RS09105 +0.4 1.9 glutathione ABC transporter permease GsiC compare
BWI76_RS21560 +0.4 2.0 DNA repair protein RecN compare
BWI76_RS20565 +0.4 0.7 hypothetical protein compare
BWI76_RS25645 +0.4 2.2 shikimate dehydrogenase compare
BWI76_RS18610 +0.4 1.9 transcriptional regulator LysR compare
BWI76_RS24265 +0.4 1.4 dienelactone hydrolase compare
BWI76_RS14890 +0.4 1.9 carbohydrate kinase compare
BWI76_RS21395 +0.4 1.4 DTW domain-containing protein compare
BWI76_RS17515 +0.4 1.7 dihydropyrimidinase compare
BWI76_RS00120 +0.4 1.7 glucosamine-6-phosphate deaminase compare
BWI76_RS16920 +0.4 1.0 3-(2,3-dihydroxyphenyl)propionate dioxygenase compare
BWI76_RS03905 +0.4 2.3 2-oxo-3-deoxygalactonate kinase compare
BWI76_RS07970 +0.4 1.2 hypothetical protein compare
BWI76_RS21660 +0.4 1.0 antirestriction protein compare
BWI76_RS12675 +0.4 1.6 putative UV protection and mutation protein compare
BWI76_RS06175 +0.4 0.9 DUF188 domain-containing protein compare
BWI76_RS17985 +0.4 1.6 hypothetical protein compare
BWI76_RS20995 +0.4 1.6 RNA degradosome polyphosphate kinase compare
BWI76_RS01120 +0.4 2.2 O-antigen translocase compare
BWI76_RS17615 +0.4 1.5 RNA pseudouridine synthase compare
BWI76_RS02745 +0.4 0.8 hypothetical protein compare
BWI76_RS02685 +0.4 2.3 opacity-associated protein compare
BWI76_RS04270 +0.4 1.4 transaldolase compare
BWI76_RS25965 +0.4 2.3 hydrolase compare
BWI76_RS16160 +0.4 1.4 LysR family transcriptional regulator compare
BWI76_RS16365 +0.4 2.7 electron transport complex subunit RsxC compare
BWI76_RS15330 +0.4 1.5 urea ABC transporter permease subunit UrtC compare
BWI76_RS26505 +0.4 1.6 nickel ABC transporter permease subunit NikB compare
BWI76_RS20530 +0.4 1.5 hypothetical protein compare


Specific Phenotypes

None in this experiment

For Klebsiella michiganensis M5al in stress experiments

For stress Fusidic acid sodium salt across organisms