Experiment set7IT056 for Marinobacter adhaerens HP15

Compare to:

marine broth with Polymyxin B sulfate 0.0004 mg/ml

200 most detrimental genes:

  gene name fitness t score description  
HP15_1655 +3.9 8.8 transcriptional regulator, TetR family compare
HP15_1805 +3.3 23.0 hydroxyacylglutathione hydrolase compare
HP15_210 +2.9 20.4 phospholipase A(1) compare
HP15_3003 +2.3 13.0 protein-export protein SecB compare
HP15_211 +2.2 5.1 conserved hypothetical protein, membrane compare
HP15_256 +2.1 15.7 serine protease compare
HP15_3324 +1.7 6.5 endonuclease/exonuclease/phosphatase compare
HP15_3819 +1.6 4.6 transcriptional regulator, DeoR, predicted compare
HP15_255 +1.4 6.5 conserved hypothetical protein compare
HP15_746 +1.4 10.4 two component transcriptional regulator, winged helix family compare
HP15_541 +1.3 6.2 peptide chain release factor 3 compare
HP15_3390 +1.3 8.6 thioesterase superfamily protein compare
HP15_600 +1.3 7.1 GGDEF domain protein compare
HP15_3184 +1.2 9.8 two-component system sensor protein compare
HP15_799 +1.2 1.6 undecaprenyl pyrophosphate phosphatase-like protein compare
HP15_212 +1.2 2.0 hypothetical protein compare
HP15_2615 +1.2 8.9 two component transcriptional regulator, winged helix family compare
HP15_1530 +1.2 3.5 RNA-binding S4 domain protein compare
HP15_1794 +1.1 1.8 secreted protein compare
HP15_747 +1.1 4.5 integral membrane sensor signal transduction histidine kinase compare
HP15_3634 +1.1 1.9 hypothetical protein compare
HP15_2509 +1.0 2.5 hypothetical protein compare
HP15_2326 +1.0 7.2 flagellar MS-ring protein compare
HP15_599 +1.0 6.9 membrane protein containing Diguanylate cyclase, predicted domains compare
HP15_3628 +1.0 1.1 hypothetical protein compare
HP15_3030 +0.9 4.2 histidine/lysine/arginine/ornithine transporter subunit compare
HP15_p187g52 +0.9 4.1 hypothetical protein compare
HP15_3556 +0.9 3.2 conserved hypothetical protein, secreted compare
HP15_2858 +0.9 3.1 hypothetical protein compare
HP15_1492 +0.9 1.5 conserved hypothetical protein compare
HP15_3032 +0.9 5.7 amino acid ABC transporter, inner membrane subunit compare
HP15_3033 +0.9 5.9 amino acid ABC transporter, inner membrane subunit compare
HP15_2981 +0.9 4.4 3-oxoacyl-(acyl-carrier-protein) synthase I compare
HP15_2982 +0.9 2.2 protein containing Helix-turn-helix, AraC domain compare
HP15_1244 +0.9 1.9 protein containing DUF1289 compare
HP15_2232 +0.9 3.9 conserved hypothetical protein, membrane compare
HP15_3031 +0.9 3.7 L-arginine ABC transporter, periplasmic substrate-binding component ArtJ/HisJ/ArtI/AotJ/ArgT (from data) compare
HP15_829 +0.9 3.0 D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase compare
HP15_3185 +0.9 5.9 conserved hypothetical protein containing DUF1745 compare
HP15_2964 +0.9 1.3 hypothetical protein compare
HP15_1553 +0.8 2.2 transcription negative regulator compare
HP15_2844 +0.8 1.7 hypothetical protein compare
HP15_1900 +0.8 2.9 dTDP-4-dehydrorhamnose 3,5-epimerase compare
HP15_524 +0.8 4.8 signal transduction histidine kinase, nitrogen specific, NtrB compare
HP15_2327 +0.8 5.6 flagellar hook-basal body complex protein FliE compare
HP15_1358 +0.8 3.2 formyltetrahydrofolate deformylase compare
HP15_3813 +0.8 4.1 conserved hypothetical protein compare
HP15_p187g24 +0.8 1.7 conserved hypothetical protein compare
HP15_2993 +0.8 6.5 conjugative transfer protein compare
HP15_293 +0.8 2.1 DNA polymerase I compare
HP15_2528 +0.8 2.0 hypothetical protein compare
HP15_3691 +0.8 5.3 phospholipid/glycerol acyltransferase compare
HP15_2638 +0.8 1.0 hypothetical protein compare
HP15_1626 +0.8 1.1 conserved hypothetical protein compare
HP15_1350 +0.8 2.6 ATP-binding component of a transport system compare
HP15_2321 +0.7 1.0 anti-sigma-factor antagonist compare
HP15_3737 +0.7 5.2 phospholipase D/transphosphatidylase compare
HP15_2969 +0.7 2.4 transcriptional regulator, MerR family compare
HP15_550 +0.7 3.2 phosphoheptose isomerase compare
HP15_950 +0.7 1.7 RNA polymerase, sigma-24 subunit, ECF subfamily compare
HP15_4030 +0.7 0.9 chloroplast-type ferredoxin compare
HP15_3104 +0.7 2.7 hypothetical protein compare
HP15_2305 +0.7 6.2 flagellar biosynthesis protein A compare
HP15_679 +0.7 1.7 conserved hypothetical protein compare
HP15_44 +0.7 3.0 DitK protein compare
HP15_2006 +0.7 3.0 hypothetical protein compare
HP15_16 +0.7 1.2 glyoxalase/bleomycin resistance protein/dioxygenase-like protein compare
HP15_3567 +0.7 1.1 conserved hypothetical protein compare
HP15_418 +0.7 2.0 conserved hypothetical protein compare
HP15_2973 +0.7 2.0 flavoprotein wrbA compare
HP15_3361 +0.7 2.3 peptidase S11, D-alanyl-D-alanine carboxypeptidase 1 compare
HP15_1695 +0.7 1.5 protein containing zinc finger, DksA/TraR C4-type domain compare
HP15_2325 +0.7 3.9 flagellar motor switch protein G compare
HP15_2183 +0.7 5.0 DNA-binding ATP-dependent protease La compare
HP15_523 +0.7 4.7 two component, sigma54 specific, transcriptional regulator, Fis family compare
HP15_1394 +0.7 2.4 thioesterase superfamily protein compare
HP15_1975 +0.7 1.0 conserved hypothetical protein compare
HP15_3060 +0.6 3.5 conserved hypothetical protein, secreted compare
HP15_1707 +0.6 1.4 short-chain dehydrogenase/reductase SDR compare
HP15_2641 +0.6 2.5 conserved hypothetical protein compare
HP15_2316 +0.6 2.7 flagellar basal body-associated protein FliL compare
HP15_1005 +0.6 2.0 acyl-CoA dehydrogenase domain protein compare
HP15_3369 +0.6 1.1 glutathione S-transferase-like protein compare
HP15_3559 +0.6 4.1 endonuclease compare
HP15_1928 +0.6 2.0 2-methylcitrate dehydratase PrpD compare
HP15_1696 +0.6 1.9 transcriptional regulator, MerR family compare
HP15_4130 +0.6 1.4 molybdopterin-guanine dinucleotide biosynthesis protein A compare
HP15_1895 +0.6 1.9 secreted protein containing PEP-CTERM bacterial domain compare
HP15_2757 +0.6 2.8 conserved hypothetical protein compare
HP15_1961 +0.6 1.7 hypothetical protein compare
HP15_71 +0.6 1.8 hypothetical protein compare
HP15_1057 +0.6 2.3 transcriptional regulator, AraC family compare
HP15_3544 +0.6 2.7 transcriptional regulator, GntR family compare
HP15_781 +0.6 2.9 GTP-binding protein LepA compare
HP15_2448 +0.6 2.3 protein belonging to uncharacterized protein family UPF0307 compare
HP15_784 +0.6 0.6 ribonuclease 3 compare
HP15_594 +0.6 2.1 peptidoglycan-binding domain 1 protein-like protein compare
HP15_3815 +0.6 1.7 organic radical activating enzyme compare
HP15_2362 +0.6 2.6 protein containing Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding domain compare
HP15_2416 +0.6 1.4 zinc-binding protein compare
HP15_2167 +0.6 2.4 transcriptional repressor for the dissimilation of sn-glycerol 3-phosphate, DeoR family protein compare
HP15_3916 +0.6 2.7 sodium-dependent transporter family protein compare
HP15_972 +0.6 1.5 hypothetical protein compare
HP15_1475 +0.6 2.8 flagellar rod assembly protein/muramidase FlgJ compare
HP15_1769 +0.6 1.7 transcriptional regulator-related protein compare
HP15_3256 +0.6 0.7 phospho-2-dehydro-3-heoxyheptonate aldolase compare
HP15_1181 +0.6 1.7 hypothetical protein compare
HP15_3038 +0.6 2.9 N-succinylarginine dihydrolase compare
HP15_3957 +0.6 2.1 endoribonuclease L-PSP family protein compare
HP15_3278 +0.6 3.5 dimethyladenosine transferase compare
HP15_2621 +0.6 1.8 branched-chain amino acid transport compare
HP15_1550 +0.6 0.9 protein/domain typically associated with flavoprotein oxygenase, DIM6/NTAB family protein compare
HP15_1606 +0.6 1.5 general secretion pathway protein I-like protein compare
HP15_800 +0.6 2.5 protein YhiQ compare
HP15_2210 +0.5 2.5 3-oxoacyl-(acyl-carrier-protein) synthase II compare
HP15_2211 +0.5 2.7 3-oxoacyl-(acyl carrier protein) synthase II compare
HP15_p42g31 +0.5 2.2 conserved hypothetical protein, secreted compare
HP15_2312 +0.5 3.8 flagellar biosynthesis protein FliP compare
HP15_3127 +0.5 1.5 methionine sulfoxide reductase B compare
HP15_2364 +0.5 1.4 nucleotide-binding protein compare
HP15_326 +0.5 3.1 polyA polymerase compare
HP15_1835 +0.5 2.7 transcriptional regulator LysR family protein compare
HP15_4096 +0.5 2.5 inner-membrane translocator compare
HP15_1774 +0.5 1.0 conserved hypothetical protein, membrane compare
HP15_1829 +0.5 1.4 tRNA pseudouridine synthase A compare
HP15_851 +0.5 1.6 integral membrane protein-like protein compare
HP15_841 +0.5 2.6 YaiI/YqxD-like protein compare
HP15_283 +0.5 2.7 methionine biosynthesis protein MetW compare
HP15_2001 +0.5 2.5 hypothetical protein compare
HP15_2227 +0.5 2.0 protein containing type IV pilus assembly PilZ domain compare
HP15_1539 +0.5 1.4 CBS domain containing protein compare
HP15_1850 +0.5 2.0 conserved hypothetical protein compare
HP15_3451 +0.5 2.3 methylglyoxal synthase compare
HP15_127 +0.5 0.8 hypothetical protein compare
HP15_574 +0.5 3.1 peptidase M23B compare
HP15_3888 +0.5 0.6 ferric siderophore transport system inner membrane protein E compare
HP15_158 +0.5 1.3 protein MerR-like protein compare
HP15_287 +0.5 0.9 pyrroline-5-carboxylate reductase compare
HP15_3615 +0.5 2.2 ribosomal RNA large subunit methyltransferase J compare
HP15_429 +0.5 3.0 GTP-binding protein TypA compare
HP15_409 +0.5 2.4 hypothetical biogenesis protein MshI-like protein compare
HP15_p187g23 +0.5 1.4 hypothetical protein compare
HP15_2206 +0.5 3.3 AraC-type DNA-binding domain-containing protein compare
HP15_3042 +0.5 2.3 acetylornithine aminotransferase (EC 2.6.1.11); succinylornithine aminotransferase (EC 2.6.1.81) (from data) compare
HP15_549 +0.5 1.8 stringent starvation protein B compare
HP15_1087 +0.5 0.8 prophage CP4-57 regulatory compare
HP15_1837 +0.5 1.9 major facilitator superfamily MFS_1 compare
HP15_p187g3 +0.5 0.8 conserved hypothetical protein, secreted compare
HP15_2330 +0.5 4.2 two component, sigma54 specific, transcriptional regulator, Fis family compare
HP15_1014 +0.5 1.4 nitrate ABC transporter, ATPase subunits C and D compare
HP15_2815 +0.5 1.6 conserved hypothetical protein, membrane compare
HP15_831 +0.5 2.7 protein containing glutaredoxin domain compare
HP15_2918 +0.5 2.8 glutamine ABC transporter, periplasmic glutamine-binding protein compare
HP15_1252 +0.5 1.3 small component of pyruvate transporter (TIGR03647) (from data) compare
HP15_3061 +0.5 2.9 conserved hypothetical protein, secreted compare
HP15_3955 +0.5 3.1 bacterial transport system permease protein compare
HP15_2838 +0.5 1.8 oxidoreductase, short chain dehydrogenase/reductase family-like protein compare
HP15_3694 +0.5 3.3 efflux transporter, RND family, MFP subunit compare
HP15_975 +0.5 0.9 hypothetical protein compare
HP15_2529 +0.5 1.5 conserved hypothetical protein compare
HP15_1468 +0.5 1.7 flagellar basal-body rod protein FlgC-like protein compare
HP15_3325 +0.5 2.0 DSBA oxidoreductase compare
HP15_3638 +0.5 2.0 antibiotic biosynthesis monooxygenase domain protein compare
HP15_1238 +0.5 2.9 transglycosylase, Slt family protein compare
HP15_2885 +0.5 1.5 secreted protein containing competence protein ComEA, helix-hairpin-helix region domain compare
HP15_2658 +0.5 2.0 nucleoside-diphosphate-sugar epimerase compare
HP15_2100 +0.5 1.7 transporting ATPase compare
HP15_2209 +0.5 2.1 4-amino-4-deoxychorismate lyase compare
HP15_1947 +0.5 0.7 hypothetical protein compare
HP15_866 +0.5 1.0 conserved hypothetical protein, membrane compare
HP15_421 +0.5 2.5 MSHA pilin protein MshD compare
HP15_3436 +0.5 0.5 hypothetical protein compare
HP15_1403 +0.5 2.3 aspartate racemase compare
HP15_204 +0.5 2.8 oligopeptide/dipeptide ABC transporter, ATPase subunit compare
HP15_2028 +0.5 0.7 protein containing alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen domain compare
HP15_1547 +0.5 1.5 response regulator receiver modulated CheW protein compare
HP15_704 +0.5 1.3 translation-associated GTPase compare
HP15_1789 +0.4 1.9 conserved hypothetical protein compare
HP15_1 +0.4 1.2 hypothetical protein compare
HP15_2314 +0.4 1.8 flagellar motor switch protein FliN-like protein compare
HP15_1446 +0.4 1.3 ribonucleotide reductase, alpha subunit compare
HP15_2585 +0.4 1.2 multiple resistance and pH regulation protein F compare
HP15_1867 +0.4 1.9 biopolymer transport protein compare
HP15_981 +0.4 0.8 conserved hypothetical protein compare
HP15_968 +0.4 1.4 hypothetical protein compare
HP15_1086 +0.4 0.7 hypothetical protein compare
HP15_3295 +0.4 3.3 zinc carboxypeptidase-related protein compare
HP15_1767 +0.4 1.8 hypothetical protein compare
HP15_2311 +0.4 2.6 flagellar biosynthetic protein FliQ compare
HP15_1528 +0.4 0.9 chromosome segregation and condensation protein ScpA compare
HP15_660 +0.4 1.4 hypothetical protein compare
HP15_3195 +0.4 1.1 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
HP15_1858 +0.4 2.1 peptidoglycan-binding domain 1 protein compare
HP15_p187g144 +0.4 1.4 hypothetical protein compare
HP15_3360 +0.4 1.8 asparaginase compare
HP15_1382 +0.4 1.6 M18-family aminopeptidase 2 compare
HP15_1080 +0.4 2.2 transcriptional Regulator, Crp/Fnr family protein compare
HP15_2131 +0.4 2.0 ATP-dependent protease HslVU (ClpYQ), ATPase subunit-like protein compare
HP15_2116 +0.4 0.8 PP-loop domain protein compare
HP15_1676 +0.4 2.2 protein containing alkylhydroperoxidase AhpD core / Carboxymuconolactone decarboxylase compare


Specific Phenotypes

For 14 genes in this experiment

For stress Polymyxin B sulfate in Marinobacter adhaerens HP15

For stress Polymyxin B sulfate across organisms