Experiment set7IT055 for Klebsiella michiganensis M5al

Compare to:

LB with Sodium nitrite 20 mM

200 most detrimental genes:

  gene name fitness t score description  
BWI76_RS18605 +1.4 2.1 oxidoreductase molybdopterin-binding protein compare
BWI76_RS05075 +1.1 1.6 type II secretion system protein GspG compare
BWI76_RS10500 +1.1 1.4 flavoprotein monooxygenase compare
BWI76_RS14320 +1.0 2.2 hypothetical protein compare
BWI76_RS06015 +1.0 1.5 hypothetical protein compare
BWI76_RS20925 +1.0 4.6 peptidase M48 compare
BWI76_RS03105 +1.0 1.6 myo-inosose-2 dehydratase compare
BWI76_RS21675 +1.0 2.2 hypothetical protein compare
BWI76_RS09455 +1.0 3.4 YbjN domain-containing protein compare
BWI76_RS20360 +1.0 1.5 cell division protein DedD compare
BWI76_RS21690 +0.9 1.5 hypothetical protein compare
BWI76_RS09195 +0.9 1.5 N-acetyltransferase compare
BWI76_RS11515 +0.9 1.0 peptide-methionine (R)-S-oxide reductase compare
BWI76_RS01070 +0.9 3.8 thiol reductase thioredoxin compare
BWI76_RS27235 +0.9 5.4 murein hydrolase activator EnvC compare
BWI76_RS01540 +0.9 2.0 thiamine biosynthesis protein ThiS compare
BWI76_RS14415 +0.9 1.6 transcriptional regulator, TetR family protein compare
BWI76_RS11260 +0.9 2.0 hypothetical protein compare
BWI76_RS04770 +0.9 3.4 D-alanine--D-alanine ligase compare
BWI76_RS12330 +0.8 2.9 hypothetical protein compare
BWI76_RS02180 +0.8 1.6 hypothetical protein compare
BWI76_RS04605 +0.8 1.6 thiamine ABC transporter ATP-binding protein compare
BWI76_RS12670 +0.8 2.1 DNA polymerase V subunit UmuD compare
BWI76_RS16895 +0.8 1.4 3-(3-hydroxy-phenyl)propionate transporter MhpT compare
BWI76_RS01775 +0.8 1.5 hypothetical protein compare
BWI76_RS12170 +0.8 2.5 hypothetical protein compare
BWI76_RS17645 +0.8 1.7 hypothetical protein compare
BWI76_RS02725 +0.8 1.0 HxlR family transcriptional regulator compare
BWI76_RS16150 +0.8 1.2 IclR family transcriptional regulator compare
BWI76_RS11255 +0.8 1.4 putrescine/spermidine ABC transporter ATP-binding protein compare
BWI76_RS19375 +0.7 2.3 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase compare
BWI76_RS12265 +0.7 2.8 hypothetical protein compare
BWI76_RS17470 +0.7 2.5 MerR family transcriptional regulator compare
BWI76_RS20965 +0.7 3.6 phosphoribosylformylglycinamidine cyclo-ligase compare
BWI76_RS16645 +0.7 2.1 DeoR family transcriptional regulator compare
BWI76_RS21130 +0.7 1.7 Fe-S assembly protein IscX compare
BWI76_RS11900 +0.7 1.1 cob(I)yrinic acid a,c-diamide adenosyltransferase compare
BWI76_RS18740 +0.7 3.0 HPP family protein compare
BWI76_RS08350 +0.7 1.6 carboxylase compare
BWI76_RS24615 +0.7 3.2 siderophore-interacting protein compare
BWI76_RS12520 +0.7 1.6 hypothetical protein compare
BWI76_RS25935 +0.7 1.4 glutathione-regulated potassium-efflux system ancillary protein KefG compare
BWI76_RS26390 +0.7 2.1 cell division protein FtsX compare
BWI76_RS21580 +0.7 1.4 SsrA-binding protein compare
BWI76_RS16205 +0.7 3.0 NAD(P) transhydrogenase subunit alpha compare
BWI76_RS18580 +0.7 0.6 hypothetical protein compare
BWI76_RS03515 +0.7 3.6 hypothetical protein compare
BWI76_RS23020 +0.7 1.3 cobalamin biosynthesis protein CbiQ compare
BWI76_RS26665 +0.7 1.5 DNA-binding response regulator compare
BWI76_RS25485 +0.7 1.3 septum formation protein Maf compare
BWI76_RS16020 +0.7 3.1 malonate decarboxylase subunit alpha compare
BWI76_RS03595 +0.7 0.7 ethanolamine utilization protein EutM compare
BWI76_RS15205 +0.7 1.9 succinate-semialdehyde dehydrogenase compare
BWI76_RS14505 +0.7 1.8 salicylate synthase Irp9 compare
BWI76_RS10910 +0.7 1.4 hypothetical protein compare
BWI76_RS10365 +0.7 2.5 class IV aminotransferase compare
BWI76_RS17935 +0.6 1.0 DUF2627 domain-containing protein compare
BWI76_RS07995 +0.6 1.4 twin-arginine translocase subunit TatA compare
BWI76_RS11770 +0.6 1.2 hypothetical protein compare
BWI76_RS14935 +0.6 0.8 NIPSNAP family containing protein compare
BWI76_RS23970 +0.6 2.1 mechanosensitive ion channel protein MscS compare
BWI76_RS04805 +0.6 1.7 8-oxo-dGTP diphosphatase compare
BWI76_RS05645 +0.6 2.1 fructuronate reductase compare
BWI76_RS11525 +0.6 1.3 HNH endonuclease compare
BWI76_RS22070 +0.6 2.7 proline/betaine ABC transporter permease ProW compare
BWI76_RS12245 +0.6 2.8 hypothetical protein compare
BWI76_RS06505 +0.6 1.8 hypothetical protein compare
BWI76_RS11060 +0.6 0.9 septum formation inhibitor Maf compare
BWI76_RS21715 +0.6 1.5 transcriptional regulator compare
BWI76_RS01520 +0.6 3.4 PTS sugar transporter subunit IIB compare
BWI76_RS21375 +0.6 0.9 autonomous glycyl radical cofactor GrcA compare
BWI76_RS18905 +0.6 1.6 putrescine/spermidine ABC transporter compare
BWI76_RS13175 +0.6 1.6 NodT family RND efflux system outer membrane lipoprotein compare
BWI76_RS07640 +0.6 1.1 short chain dehydrogenase compare
BWI76_RS19360 +0.6 2.0 glucose dehydrogenase compare
BWI76_RS25430 +0.6 3.4 membrane protein compare
BWI76_RS02245 +0.6 2.7 hypothetical protein compare
BWI76_RS00565 +0.6 1.6 branched-chain amino acid transport compare
BWI76_RS23320 +0.6 1.0 hypothetical protein compare
BWI76_RS09440 +0.6 0.9 hypothetical protein compare
BWI76_RS06110 +0.6 2.8 hypothetical protein compare
BWI76_RS02775 +0.6 1.9 outer membrane protein assembly factor compare
BWI76_RS16200 +0.6 1.5 NAD(P) transhydrogenase subunit beta compare
BWI76_RS24335 +0.6 1.9 two-component system response regulator QseB compare
BWI76_RS15800 +0.6 1.5 transcriptional regulator compare
BWI76_RS01545 +0.6 1.4 thiamine biosynthesis protein ThiS compare
BWI76_RS12180 +0.6 2.7 membrane protein compare
BWI76_RS13560 +0.6 0.8 amino acid ABC transporter substrate-binding subunit compare
BWI76_RS16910 +0.6 1.4 2-keto-4-pentenoate hydratase compare
BWI76_RS12680 +0.6 1.2 oxidoreductase compare
BWI76_RS23050 +0.6 1.2 cobalt-precorrin-3B C(17)-methyltransferase compare
BWI76_RS06770 +0.6 3.4 Hha toxicity attenuator compare
BWI76_RS15895 +0.6 3.6 starvation-sensing protein RspA compare
BWI76_RS16535 +0.6 3.3 MATE family efflux transporter compare
BWI76_RS14780 +0.6 1.0 phosphotriesterase compare
BWI76_RS10730 +0.6 0.9 bifunctional glucose-1-phosphatase/inositol phosphatase compare
BWI76_RS26120 +0.6 2.2 hypothetical protein compare
BWI76_RS13155 +0.6 1.2 hypothetical protein compare
BWI76_RS06870 +0.6 1.6 aminoacyl-tRNA deacylase compare
BWI76_RS20730 +0.5 1.0 hypothetical protein compare
BWI76_RS16470 +0.5 0.9 transcriptional repressor NemR compare
BWI76_RS21165 +0.5 1.2 Fe-S cluster assembly transcriptional regulator IscR compare
BWI76_RS05525 +0.5 2.1 glycerophosphodiester phosphodiesterase compare
BWI76_RS12790 +0.5 0.7 lactate dehydrogenase compare
BWI76_RS17375 +0.5 1.3 nitrate ABC transporter, permease protein compare
BWI76_RS05425 +0.5 1.5 EEP domain-containing protein compare
BWI76_RS27605 +0.5 1.5 hypothetical protein compare
BWI76_RS11465 +0.5 1.5 hypothetical protein compare
BWI76_RS16015 +0.5 2.1 pheromone autoinducer 2 transporter compare
BWI76_RS05350 +0.5 2.9 Rcs stress response system protein RcsF compare
BWI76_RS24155 +0.5 2.4 A/G-specific adenine glycosylase compare
BWI76_RS10875 +0.5 0.9 quercetin 2,3-dioxygenase compare
BWI76_RS20050 +0.5 0.9 hypothetical protein compare
BWI76_RS12215 +0.5 1.8 HNH endonuclease compare
BWI76_RS16685 +0.5 2.1 peptide ABC transporter permease compare
BWI76_RS13025 +0.5 1.6 histidine phosphatase family protein compare
BWI76_RS15435 +0.5 0.8 hypothetical protein compare
BWI76_RS07095 +0.5 2.3 ribosome-associated protein compare
BWI76_RS05885 +0.5 1.0 anion permease compare
BWI76_RS13090 +0.5 1.1 phenylacetate-CoA oxygenase subunit PaaA compare
BWI76_RS07865 +0.5 0.9 methylthioribulose 1-phosphate dehydratase compare
BWI76_RS04060 +0.5 0.9 hypothetical protein compare
BWI76_RS24210 +0.5 2.3 cystathionine gamma-lyase compare
BWI76_RS06325 +0.5 1.5 hypothetical protein compare
BWI76_RS12300 +0.5 3.5 hypothetical protein compare
BWI76_RS02695 +0.5 1.8 peptidyl-prolyl cis-trans isomerase compare
BWI76_RS18305 +0.5 1.6 dihydrodipicolinate synthase family protein compare
BWI76_RS12125 +0.5 1.0 hypothetical protein compare
BWI76_RS26290 +0.5 1.3 glycerol-3-phosphate ABC transporter ATP-binding protein compare
BWI76_RS09680 +0.5 1.3 dimethyl sulfoxide reductase subunit A compare
BWI76_RS16850 +0.5 3.0 ABC transporter periplasmic substrate-binding protein compare
BWI76_RS12255 +0.5 3.3 hypothetical protein compare
BWI76_RS13320 +0.5 1.6 putative LpxA-like enzyme compare
BWI76_RS15050 +0.5 1.0 sugar transporter compare
BWI76_RS09420 +0.5 1.1 hypothetical protein compare
BWI76_RS12235 +0.5 0.7 hypothetical protein compare
BWI76_RS27510 +0.5 1.9 aquaporin compare
BWI76_RS22260 +0.5 2.3 anaerobic nitric oxide reductase flavorubredoxin compare
BWI76_RS10685 +0.5 2.6 LysR family transcriptional regulator compare
BWI76_RS21395 +0.5 1.4 DTW domain-containing protein compare
BWI76_RS16840 +0.5 2.0 ABC transporter compare
BWI76_RS21920 +0.5 1.7 amino acid ABC transporter substrate-binding protein compare
BWI76_RS01325 +0.5 0.7 twin-arginine translocase subunit TatB compare
BWI76_RS08675 +0.5 2.3 GntR family transcriptional regulator compare
BWI76_RS12095 +0.5 2.2 hypothetical protein compare
BWI76_RS19575 +0.5 1.6 maleylacetoacetate isomerase compare
BWI76_RS01580 +0.5 0.8 hypothetical protein compare
BWI76_RS16230 +0.5 1.0 dihydromonapterin reductase compare
BWI76_RS16575 +0.5 1.9 cytochrome ubiquinol oxidase subunit I compare
BWI76_RS13415 +0.5 1.0 spermidine/putrescine ABC transporter permease compare
BWI76_RS25295 +0.5 0.7 glutamine amidotransferase compare
BWI76_RS05970 +0.5 1.6 hypothetical protein compare
BWI76_RS09135 +0.5 1.2 oxidoreductase compare
BWI76_RS08380 +0.5 0.5 endonuclease VIII compare
BWI76_RS00760 +0.5 1.9 cell division protein FtsN compare
BWI76_RS12205 +0.5 2.0 hypothetical protein compare
BWI76_RS17970 +0.5 1.1 zinc metalloprotease HtpX compare
BWI76_RS11015 +0.5 0.9 hypothetical protein compare
BWI76_RS01000 +0.5 1.1 peptidyl-prolyl cis-trans isomerase compare
BWI76_RS12420 +0.5 0.7 peptide ABC transporter substrate-binding protein SapA compare
BWI76_RS09670 +0.5 1.9 recombination factor protein RarA compare
BWI76_RS23920 +0.5 2.2 D-3-phosphoglycerate dehydrogenase compare
BWI76_RS16420 +0.5 1.4 anhydro-N-acetylmuramic acid kinase compare
BWI76_RS14975 +0.5 1.7 glyoxalase-like domain protein compare
BWI76_RS23455 +0.5 0.9 Na(+)-translocating NADH-quinone reductase subunit E compare
BWI76_RS24480 +0.5 2.8 undecaprenyl-diphosphatase compare
BWI76_RS13135 +0.5 0.9 3-oxoadipyl-CoA thiolase compare
BWI76_RS15210 +0.5 0.9 LysR family transcriptional regulator compare
BWI76_RS12445 +0.5 1.1 phage shock protein operon transcriptional activator compare
BWI76_RS19525 +0.5 2.0 D-alanyl-D-alanine endopeptidase compare
BWI76_RS04815 +0.5 0.9 cell division protein ZapD compare
BWI76_RS17870 +0.5 1.6 coenzyme A pyrophosphatase compare
BWI76_RS16920 +0.5 0.5 3-(2,3-dihydroxyphenyl)propionate dioxygenase compare
BWI76_RS08245 +0.5 1.2 MFS transporter compare
BWI76_RS16240 +0.5 0.8 anti-adapter protein IraM compare
BWI76_RS07110 +0.4 1.6 DNA-binding protein compare
BWI76_RS14435 +0.4 0.7 glutamine ABC transporter ATP-binding protein compare
BWI76_RS14800 +0.4 1.1 non-heme chloroperoxidase compare
BWI76_RS13490 +0.4 1.7 pyrimidine-specific ribonucleoside hydrolase RihA compare
BWI76_RS27610 +0.4 1.1 hydroxyacid dehydrogenase compare
BWI76_RS13215 +0.4 0.8 type I glyceraldehyde-3-phosphate dehydrogenase compare
BWI76_RS16475 +0.4 2.1 alkene reductase compare
BWI76_RS08635 +0.4 2.4 molybdenum-dependent transcriptional regulator compare
BWI76_RS06510 +0.4 1.3 BolA family transcriptional regulator compare
BWI76_RS05945 +0.4 1.3 amino acid ABC transporter permease compare
BWI76_RS16055 +0.4 2.8 malonate decarboxylase subunit epsilon compare
BWI76_RS07605 +0.4 1.1 N-acetyltransferase GCN5 compare
BWI76_RS14245 +0.4 1.4 carboxymuconolactone decarboxylase family protein compare
BWI76_RS27515 +0.4 3.2 glycerol kinase compare
BWI76_RS13400 +0.4 1.2 GntR family transcriptional regulator compare
BWI76_RS13300 +0.4 1.7 carboxylesterase compare
BWI76_RS14040 +0.4 1.9 thiaminase compare
BWI76_RS27365 +0.4 1.3 hypothetical protein compare
BWI76_RS12135 +0.4 3.2 C-5 cytosine-specific DNA methylase compare
BWI76_RS11535 +0.4 1.3 putative oxidoreductase, Zn-dependent and NAD(P)-binding protein compare
BWI76_RS01620 +0.4 0.9 hypothetical protein compare
BWI76_RS23555 +0.4 1.7 type 1 major fimbrial subunit precursor compare
BWI76_RS27835 +0.4 1.2 acyltransferase compare
BWI76_RS24260 +0.4 1.5 hypothetical protein compare
BWI76_RS13515 +0.4 1.8 amino acid permease compare


Specific Phenotypes

None in this experiment

For Klebsiella michiganensis M5al in stress experiments

For stress Sodium nitrite across organisms