Experiment set7IT054 for Methanococcus maripaludis S2

Compare to:

Iron excess (5x) , formate media

200 most important genes:

  gene name fitness t score description  
MMP_RS06355 -5.4 -5.2 molybdenum cofactor biosynthesis protein MoaE compare
MMP_RS01005 -5.1 -2.1 riboflavin synthase compare
MMP_RS01020 -4.5 -2.2 3 4-dihydroxy-2-butanone-4-phosphate synthase compare
MMP_RS03015 -4.4 -20.6 GTP 3' 8-cyclase MoaA compare
MMP_RS05515 -4.3 -13.3 cyclic pyranopterin monophosphate synthase MoaC compare
MMP_RS06680 -4.1 -22.2 Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain compare
MMP_RS06350 -4.1 -9.4 HesA/MoeB/ThiF family protein compare
MMP_RS06700 -4.1 -20.7 hypothetical protein compare
MMP_RS01175 -3.9 -10.7 triphosphoribosyl-dephospho-CoA synthase compare
MMP_RS07635 -3.8 -11.4 MogA/MoaB family molybdenum cofactor biosynthesis protein compare
MMP_RS06685 -3.8 -17.3 formate dehydrogenase H subunit alpha selenocysteine-containing compare
MMP_RS04890 -3.6 -1.4 adenylyltransferase/cytidyltransferase family protein compare
MMP_RS01385 -3.5 -1.4 imidazole glycerol phosphate synthase subunit HisH compare
MMP_RS06345 -3.4 -14.5 formate dehydrogenase accessory sulfurtransferase FdhD compare
MMP_RS01755 -3.3 -2.9 DUF2097 domain-containing protein compare
MMP_RS03315 -3.3 -2.2 ferrous iron transport protein A compare
MMP_RS02010 -3.2 -14.1 PHP domain-containing protein compare
MMP_RS08720 -3.2 -3.1 4Fe-4S binding protein compare
MMP_RS06715 -3.1 -19.3 cache domain-containing protein compare
MMP_RS01500 -3.0 -5.7 CBS domain-containing protein compare
MMP_RS00040 -2.9 -5.6 TIGR03576 family pyridoxal phosphate-dependent enzyme compare
MMP_RS08820 -2.9 -10.2 hypothetical protein compare
MMP_RS07845 -2.8 -4.6 LL-diaminopimelate aminotransferase compare
MMP_RS04585 -2.8 -12.8 AIR synthase related protein compare
MMP_RS04605 -2.7 -10.4 cobalt ECF transporter T component CbiQ compare
MMP_RS04780 -2.7 -5.1 ribonuclease P compare
MMP_RS06720 -2.7 -9.2 response regulator transcription factor compare
MMP_RS01545 -2.7 -2.3 CBS domain-containing protein compare
MMP_RS00305 -2.6 -3.6 phosphoribosyl-ATP diphosphatase compare
MMP_RS07445 -2.6 -8.1 helix-turn-helix domain-containing protein compare
MMP_RS04900 -2.5 -19.8 hypothetical protein compare
MMP_RS06105 -2.4 -9.3 hydrogenase maturation peptidase HycI compare
MMP_RS06895 -2.4 -3.5 selenocysteine-specific translation elongation factor compare
MMP_RS06705 -2.4 -10.0 formate/nitrite transporter family protein compare
MMP_RS06285 -2.4 -5.4 precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT compare
MMP_RS07525 -2.4 -10.6 4Fe-4S binding protein compare
MMP_RS03475 -2.3 -1.5 hypothetical protein compare
MMP_RS03600 -2.3 -4.1 triose-phosphate isomerase compare
MMP_RS08745 -2.3 -10.6 CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase compare
MMP_RS06295 -2.3 -9.9 methanogenesis marker 14 protein compare
MMP_RS00895 -2.2 -5.5 hypothetical protein compare
MMP_RS01980 -2.2 -14.1 trimeric intracellular cation channel family protein compare
MMP_RS06730 -2.2 -3.9 phosphopantothenate/pantothenate synthetase compare
MMP_RS08300 -2.1 -2.1 metal-sulfur cluster assembly factor compare
MMP_RS03025 -2.1 -6.6 molybdenum cofactor guanylyltransferase compare
MMP_RS08460 -2.1 -4.7 proteasome-activating nucleotidase compare
MMP_RS08645 -2.1 -10.1 UPF0179 family protein compare
MMP_RS00695 -2.1 -1.8 biotin--[acetyl-CoA-carboxylase] ligase compare
MMP_RS00115 -2.1 -13.5 radical SAM protein compare
MMP_RS04500 -2.1 -14.5 adenosylmethionine--8-amino-7-oxononanoate transaminase compare
MMP_RS08105 -2.1 -7.4 6-carboxyhexanoate--CoA ligase compare
MMP_RS01220 -2.1 -10.7 hypothetical protein compare
MMP_RS00685 -2.1 -5.3 2-phospho-L-lactate guanylyltransferase compare
MMP_RS04620 -2.1 -12.9 cobalt transporter CbiM compare
MMP_RS07630 -2.0 -3.1 ATP-binding cassette domain-containing protein compare
MMP_RS08210 -2.0 -4.2 phosphatidylglycerophosphatase A compare
MMP_RS02195 -2.0 -4.5 tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase compare
MMP_RS06400 -2.0 -2.2 4Fe-4S binding protein compare
MMP_RS01265 -2.0 -2.4 hypothetical protein compare
MMP_RS02280 -2.0 -1.7 DUF211 domain-containing protein compare
MMP_RS01985 -2.0 -7.9 F420-dependent methylenetetrahydromethanopterin dehydrogenase compare
MMP_RS00300 -2.0 -1.3 6 7-dimethyl-8-ribityllumazine synthase compare
MMP_RS08095 -2.0 -9.5 dethiobiotin synthase compare
MMP_RS08715 -2.0 -2.6 formylmethanofuran dehydrogenase subunit B compare
MMP_RS03205 -1.9 -2.3 peptidyl-tRNA hydrolase Pth2 compare
MMP_RS08100 -1.9 -7.8 8-amino-7-oxononanoate synthase compare
MMP_RS02240 -1.9 -4.9 methanogenesis marker 7 protein compare
MMP_RS04615 -1.9 -4.4 PDGLE domain-containing protein compare
MMP_RS07600 -1.9 -5.1 Ni-sirohydrochlorin a c-diamide synthase compare
MMP_RS08435 -1.8 -2.4 Era-like GTP-binding protein compare
MMP_RS02800 -1.8 -6.3 nucleotidyltransferase domain-containing protein compare
MMP_RS08635 -1.8 -3.0 UbiA family prenyltransferase compare
MMP_RS07005 -1.8 -1.1 4Fe-4S binding protein compare
MMP_RS06475 -1.8 -5.0 FAD-dependent oxidoreductase compare
MMP_RS02355 -1.8 -4.6 30S ribosomal protein S27ae compare
MMP_RS07755 -1.8 -2.4 DUF555 domain-containing protein compare
MMP_RS01250 -1.7 -6.8 tRNA (guanine(26)-N(2))-dimethyltransferase compare
MMP_RS02190 -1.7 -5.3 sulfopyruvate decarboxylase subunit alpha compare
MMP_RS04870 -1.7 -7.5 TIGR02253 family HAD-type hydrolase compare
MMP_RS04775 -1.7 -3.6 adenosylhomocysteinase compare
MMP_RS02340 -1.7 -3.1 DNA-directed RNA polymerase subunit E'' compare
MMP_RS03640 -1.7 -4.4 archaeal proteasome endopeptidase complex subunit beta compare
MMP_RS06370 -1.7 -5.2 biotin synthase BioB compare
MMP_RS00515 -1.6 -1.4 DUF655 domain-containing protein compare
MMP_RS01610 -1.6 -4.4 hypothetical protein compare
MMP_RS00110 -1.6 -4.5 hypothetical protein compare
MMP_RS08790 -1.6 -3.9 translation initiation factor IF-2 subunit alpha compare
MMP_RS05765 -1.6 -6.2 M42 family metallopeptidase compare
MMP_RS06885 -1.6 -3.5 50S ribosome-binding GTPase compare
MMP_RS04685 -1.6 -3.7 DUF126 domain-containing protein compare
MMP_RS01380 -1.6 -4.3 PHP domain-containing protein compare
MMP_RS05540 -1.6 -3.8 hypothetical protein compare
MMP_RS02165 -1.6 -7.1 tRNA-dihydrouridine synthase compare
MMP_RS05430 -1.5 -5.1 TIGR00288 family NYN domain-containing protein compare
MMP_RS01725 -1.5 -4.9 class I SAM-dependent methyltransferase family protein compare
MMP_RS00130 -1.5 -2.1 nickel-responsive transcriptional regulator NikR compare
MMP_RS01800 -1.5 -4.4 TIGR00303 family protein compare
MMP_RS00520 -1.5 -2.8 RNA polymerase Rpb4 family protein compare
MMP_RS07545 -1.5 -1.3 HTH domain-containing protein compare
MMP_RS05845 -1.4 -2.8 tRNA-intron lyase compare
MMP_RS06270 -1.4 -6.6 TIGR00300 family protein compare
MMP_RS07645 -1.4 -5.9 aldehyde dehydrogenase family protein compare
MMP_RS07685 -1.4 -5.5 TIGR01212 family radical SAM protein compare
MMP_RS06020 -1.4 -4.5 archaeoflavoprotein AfpA compare
MMP_RS06930 -1.4 -8.8 MBL fold metallo-hydrolase compare
MMP_RS07765 -1.4 -7.5 sodium:alanine symporter family protein compare
MMP_RS06175 -1.4 -6.0 winged helix-turn-helix transcriptional regulator compare
MMP_RS00620 -1.4 -7.6 4Fe-4S binding protein compare
MMP_RS07575 -1.4 -3.4 RNA ligase partner protein compare
MMP_RS07365 -1.4 -9.5 2-phosphoglycerate kinase compare
MMP_RS08940 -1.3 -2.1 MetS family NSS transporter small subunit compare
MMP_RS05245 -1.3 -7.8 archaeosine biosynthesis radical SAM protein RaSEA compare
MMP_RS02235 -1.3 -8.2 CBS domain-containing protein compare
MMP_RS06230 -1.3 -3.5 helix-turn-helix domain-containing protein compare
MMP_RS01795 -1.3 -2.7 methanogenesis marker 6 protein compare
MMP_RS08320 -1.3 -5.6 molybdopterin molybdotransferase MoeA compare
MMP_RS03035 -1.3 -3.2 4-hydroxy-tetrahydrodipicolinate synthase compare
MMP_RS01365 -1.3 -4.1 archaeal proteasome endopeptidase complex subunit alpha compare
MMP_RS03080 -1.3 -1.9 universal stress protein compare
MMP_RS05510 -1.3 -4.6 Rrf2 family transcriptional regulator compare
MMP_RS07380 -1.2 -2.3 transcription elongation factor Spt5 compare
MMP_RS03960 -1.2 -1.4 hypothetical protein compare
MMP_RS07735 -1.2 -1.5 2-ketoisovalerate ferredoxin oxidoreductase subunit alpha compare
MMP_RS01225 -1.2 -5.5 DUF5379 domain-containing protein compare
MMP_RS05875 -1.2 -4.7 hydroxyethylthiazole kinase compare
MMP_RS03580 -1.2 -3.5 signal recognition particle-docking protein FtsY compare
MMP_RS06630 -1.2 -1.2 UPF0058 family protein compare
MMP_RS05815 -1.2 -1.9 NOL1/NOP2/sun family putative RNA methylase compare
MMP_RS00295 -1.2 -1.9 gamma carbonic anhydrase family protein compare
MMP_RS00915 -1.2 -5.5 DUF116 domain-containing protein compare
MMP_RS06975 -1.2 -2.9 sulfide-dependent adenosine diphosphate thiazole synthase compare
MMP_RS06200 -1.2 -6.5 M24 family metallopeptidase compare
MMP_RS06215 -1.1 -2.7 30S ribosomal protein S6e compare
MMP_RS00555 -1.1 -5.3 MFS transporter compare
MMP_RS03400 -1.1 -3.0 archease compare
MMP_RS04710 -1.1 -2.4 hypothetical protein compare
MMP_RS08690 -1.1 -6.2 RNA-guided pseudouridylation complex pseudouridine synthase subunit Cbf5 compare
MMP_RS03435 -1.1 -1.2 ketol-acid reductoisomerase compare
MMP_RS06625 -1.1 -1.8 DNA primase compare
MMP_RS05250 -1.1 -1.9 NFYB/HAP3 family transcription factor subunit compare
MMP_RS05555 -1.1 -2.1 DUF4040 domain-containing protein compare
MMP_RS01195 -1.1 -1.6 metalloregulator ArsR/SmtB family transcription factor compare
MMP_RS01075 -1.1 -2.2 hypothetical protein compare
MMP_RS07775 -1.0 -4.0 alanine dehydrogenase compare
MMP_RS03095 -1.0 -4.6 diphthine synthase compare
MMP_RS07425 -1.0 -4.3 GTP-binding protein compare
MMP_RS06120 -1.0 -2.0 UPF0147 family protein compare
MMP_RS09020 -1.0 -1.5 hypothetical protein compare
MMP_RS02345 -1.0 -2.6 GTP-dependent dephospho-CoA kinase family protein compare
MMP_RS07195 -1.0 -5.8 M20 family metallo-hydrolase compare
MMP_RS08725 -1.0 -1.7 Ni/Fe hydrogenase subunit alpha compare
MMP_RS02930 -1.0 -2.3 class I SAM-dependent methyltransferase compare
MMP_RS07200 -1.0 -3.6 [5-(aminomethyl)furan-3-yl]methyl phosphate kinase compare
MMP_RS06865 -0.9 -1.3 HypC/HybG/HupF family hydrogenase formation chaperone compare
MMP_RS05545 -0.9 -4.3 pyridoxal phosphate-dependent aminotransferase compare
MMP_RS06840 -0.9 -1.1 DNA-directed RNA polymerase subunit N compare
MMP_RS06925 -0.9 -2.2 ribonuclease VapC4 compare
MMP_RS06855 -0.9 -5.3 hypothetical protein compare
MMP_RS01700 -0.9 -0.9 dihydroxy-acid dehydratase compare
MMP_RS01840 -0.9 -4.9 TIGR00289 family protein compare
MMP_RS00050 -0.9 -4.0 AarF/UbiB family protein compare
MMP_RS05550 -0.9 -0.8 cation:proton antiporter compare
MMP_RS07605 -0.9 -2.4 diadenylate cyclase compare
MMP_RS08650 -0.8 -2.8 glutamine--fructose-6-phosphate transaminase (isomerizing) compare
MMP_RS03590 -0.8 -4.1 METTL5 family protein compare
MMP_RS08200 -0.8 -7.0 archaeosine synthase subunit alpha compare
MMP_RS05440 -0.8 -5.1 winged helix-turn-helix transcriptional regulator compare
MMP_RS02175 -0.8 -0.8 DUF1611 domain-containing protein compare
MMP_RS02875 -0.8 -5.5 chorismate pyruvate-lyase family protein compare
MMP_RS03700 -0.8 -4.9 sodium:proton antiporter compare
MMP_RS06340 -0.8 -3.5 phosphoadenosine phosphosulfate reductase family protein compare
MMP_RS01325 -0.8 -1.4 dihydroneopterin aldolase family protein compare
MMP_RS04955 -0.8 -2.6 DNA topoisomerase I compare
MMP_RS06940 -0.8 -2.0 polyprenyl diphosphate synthase compare
MMP_RS04695 -0.8 -4.6 selenide water dikinase SelD compare
MMP_RS00320 -0.8 -1.9 class I SAM-dependent methyltransferase compare
MMP_RS07710 -0.8 -3.5 cell division protein FtsZ compare
MMP_RS00290 -0.8 -4.6 hypothetical protein compare
MMP_RS07535 -0.8 -4.0 4Fe-4S binding protein compare
MMP_RS05425 -0.7 -3.1 monovalent cation/H+ antiporter complex subunit F compare
MMP_RS02900 -0.7 -0.5 imidazoleglycerol-phosphate dehydratase HisB compare
MMP_RS00535 -0.7 -1.4 TIGR00375 family protein compare
MMP_RS00850 -0.7 -2.7 TIGR01177 family methyltransferase compare
MMP_RS01960 -0.7 -1.0 hypothetical protein compare
MMP_RS08615 -0.7 -1.7 flagellar protein G compare
MMP_RS01180 -0.7 -0.9 XTP/dITP diphosphatase compare
MMP_RS00810 -0.7 -4.8 topoisomerase DNA-binding C4 zinc finger domain-containing protein compare
MMP_RS02885 -0.7 -5.4 molybdopterin biosynthesis protein compare
MMP_RS05345 -0.7 -2.8 hypothetical protein compare
MMP_RS09055 -0.7 -0.9 CAP domain-containing protein compare
MMP_RS03155 -0.7 -2.8 precorrin-6A reductase compare
MMP_RS00985 -0.7 -2.9 CDC48 family AAA ATPase compare
MMP_RS01045 -0.7 -3.8 diphthamide biosynthesis enzyme Dph2 compare
MMP_RS02170 -0.7 -2.8 CBS domain-containing protein compare
MMP_RS04125 -0.7 -2.2 TetR/AcrR family transcriptional regulator compare
MMP_RS08165 -0.7 -1.5 phosphoglycerate dehydrogenase compare
MMP_RS01440 -0.7 -3.4 NAAT family transporter compare
MMP_RS03210 -0.6 -4.6 tRNA guanosine(15) transglycosylase TgtA compare
MMP_RS06915 -0.6 -2.3 metallophosphoesterase compare
MMP_RS02135 -0.6 -1.3 DUF5612 domain-containing protein compare


Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in iron experiments

For iron Iron (II) chloride tetrahydrate across organisms