Experiment set7IT053 for Methanococcus maripaludis S2

200 most important genes:

gene	name	fitness	t score	description
MMP_RS06355		-5.4	-4.4	molybdenum cofactor biosynthesis protein MoaE
MMP_RS01175		-4.8	-8.3	triphosphoribosyl-dephospho-CoA synthase
MMP_RS06350		-4.7	-10.9	HesA/MoeB/ThiF family protein
MMP_RS03315		-4.5	-3.0	ferrous iron transport protein A
MMP_RS03015		-4.5	-16.6	GTP 3' 8-cyclase MoaA
MMP_RS06685		-4.4	-19.8	formate dehydrogenase H subunit alpha selenocysteine-containing
MMP_RS06680		-4.3	-21.2	Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain
MMP_RS01020		-4.3	-2.0	3 4-dihydroxy-2-butanone-4-phosphate synthase
MMP_RS06700		-4.2	-17.8	hypothetical protein
MMP_RS05515		-4.1	-10.6	cyclic pyranopterin monophosphate synthase MoaC
MMP_RS07635		-3.7	-10.1	MogA/MoaB family molybdenum cofactor biosynthesis protein
MMP_RS04890		-3.5	-1.4	adenylyltransferase/cytidyltransferase family protein
MMP_RS06345		-3.4	-14.8	formate dehydrogenase accessory sulfurtransferase FdhD
MMP_RS01005		-3.3	-2.2	riboflavin synthase
MMP_RS02010		-3.3	-14.7	PHP domain-containing protein
MMP_RS00040		-3.2	-6.0	TIGR03576 family pyridoxal phosphate-dependent enzyme
MMP_RS06715		-3.1	-20.3	cache domain-containing protein
MMP_RS08720		-2.9	-3.5	4Fe-4S binding protein
MMP_RS08820		-2.8	-8.4	hypothetical protein
MMP_RS00300		-2.8	-1.3	6 7-dimethyl-8-ribityllumazine synthase
MMP_RS01385		-2.8	-1.3	imidazole glycerol phosphate synthase subunit HisH
MMP_RS04585		-2.8	-12.9	AIR synthase related protein
MMP_RS04605		-2.7	-7.3	cobalt ECF transporter T component CbiQ
MMP_RS08635		-2.7	-4.0	UbiA family prenyltransferase
MMP_RS02195		-2.7	-6.0	tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase
MMP_RS01795		-2.7	-2.8	methanogenesis marker 6 protein
MMP_RS07445		-2.6	-8.2	helix-turn-helix domain-containing protein
MMP_RS01265		-2.6	-3.4	hypothetical protein
MMP_RS03435		-2.6	-2.7	ketol-acid reductoisomerase
MMP_RS04900		-2.5	-19.7	hypothetical protein
MMP_RS06105		-2.5	-8.5	hydrogenase maturation peptidase HycI
MMP_RS06720		-2.5	-10.4	response regulator transcription factor
MMP_RS08745		-2.5	-11.5	CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase
MMP_RS07545		-2.5	-1.9	HTH domain-containing protein
MMP_RS01500		-2.5	-3.3	CBS domain-containing protein
MMP_RS03475		-2.5	-1.4	hypothetical protein
MMP_RS08715		-2.4	-2.8	formylmethanofuran dehydrogenase subunit B
MMP_RS07525		-2.4	-10.1	4Fe-4S binding protein
MMP_RS08645		-2.4	-9.6	UPF0179 family protein
MMP_RS06705		-2.4	-8.8	formate/nitrite transporter family protein
MMP_RS03600		-2.4	-4.0	triose-phosphate isomerase
MMP_RS01610		-2.3	-6.4	hypothetical protein
MMP_RS04685		-2.3	-6.2	DUF126 domain-containing protein
MMP_RS01980		-2.3	-14.6	trimeric intracellular cation channel family protein
MMP_RS03640		-2.3	-7.8	archaeal proteasome endopeptidase complex subunit beta
MMP_RS02900		-2.3	-1.0	imidazoleglycerol-phosphate dehydratase HisB
MMP_RS02240		-2.2	-6.4	methanogenesis marker 7 protein
MMP_RS04780		-2.2	-5.6	ribonuclease P
MMP_RS06295		-2.2	-9.5	methanogenesis marker 14 protein
MMP_RS00115		-2.2	-14.1	radical SAM protein
MMP_RS04500		-2.2	-14.8	adenosylmethionine--8-amino-7-oxononanoate transaminase
MMP_RS00895		-2.2	-4.7	hypothetical protein
MMP_RS00685		-2.2	-6.8	2-phospho-L-lactate guanylyltransferase
MMP_RS08790		-2.2	-3.1	translation initiation factor IF-2 subunit alpha
MMP_RS08100		-2.2	-9.3	8-amino-7-oxononanoate synthase
MMP_RS03025		-2.2	-8.3	molybdenum cofactor guanylyltransferase
MMP_RS01220		-2.1	-10.3	hypothetical protein
MMP_RS07845		-2.1	-3.5	LL-diaminopimelate aminotransferase
MMP_RS02355		-2.1	-5.4	30S ribosomal protein S27ae
MMP_RS08095		-2.1	-7.6	dethiobiotin synthase
MMP_RS01755		-2.0	-2.6	DUF2097 domain-containing protein
MMP_RS09020		-2.0	-2.6	hypothetical protein
MMP_RS06285		-2.0	-5.1	precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT
MMP_RS01985		-2.0	-8.9	F420-dependent methylenetetrahydromethanopterin dehydrogenase
MMP_RS03960		-2.0	-1.7	hypothetical protein
MMP_RS04775		-2.0	-4.0	adenosylhomocysteinase
MMP_RS08105		-2.0	-9.3	6-carboxyhexanoate--CoA ligase
MMP_RS06020		-1.9	-7.4	archaeoflavoprotein AfpA
MMP_RS04620		-1.9	-12.6	cobalt transporter CbiM
MMP_RS07630		-1.9	-1.9	ATP-binding cassette domain-containing protein
MMP_RS06975		-1.9	-2.6	sulfide-dependent adenosine diphosphate thiazole synthase
MMP_RS06475		-1.8	-6.6	FAD-dependent oxidoreductase
MMP_RS04615		-1.8	-3.9	PDGLE domain-containing protein
MMP_RS06270		-1.8	-6.7	TIGR00300 family protein
MMP_RS08435		-1.7	-3.3	Era-like GTP-binding protein
MMP_RS06230		-1.7	-2.9	helix-turn-helix domain-containing protein
MMP_RS04710		-1.7	-2.7	hypothetical protein
MMP_RS07730		-1.7	-2.3	pyruvate synthase subunit beta
MMP_RS08460		-1.7	-2.7	proteasome-activating nucleotidase
MMP_RS02800		-1.7	-7.0	nucleotidyltransferase domain-containing protein
MMP_RS05765		-1.7	-7.5	M42 family metallopeptidase
MMP_RS01225		-1.7	-6.6	DUF5379 domain-containing protein
MMP_RS07645		-1.7	-5.7	aldehyde dehydrogenase family protein
MMP_RS01800		-1.6	-3.3	TIGR00303 family protein
MMP_RS07685		-1.6	-7.5	TIGR01212 family radical SAM protein
MMP_RS08300		-1.6	-1.7	metal-sulfur cluster assembly factor
MMP_RS05540		-1.6	-4.0	hypothetical protein
MMP_RS07600		-1.6	-4.0	Ni-sirohydrochlorin a c-diamide synthase
MMP_RS06370		-1.6	-5.4	biotin synthase BioB
MMP_RS07765		-1.6	-7.3	sodium:alanine symporter family protein
MMP_RS00620		-1.6	-7.2	4Fe-4S binding protein
MMP_RS02280		-1.6	-1.4	DUF211 domain-containing protein
MMP_RS07575		-1.6	-3.2	RNA ligase partner protein
MMP_RS04870		-1.6	-5.6	TIGR02253 family HAD-type hydrolase
MMP_RS01380		-1.6	-6.1	PHP domain-containing protein
MMP_RS03400		-1.5	-3.3	archease
MMP_RS02235		-1.5	-9.6	CBS domain-containing protein
MMP_RS03035		-1.5	-4.0	4-hydroxy-tetrahydrodipicolinate synthase
MMP_RS02165		-1.5	-6.0	tRNA-dihydrouridine synthase
MMP_RS07380		-1.5	-2.4	transcription elongation factor Spt5
MMP_RS01250		-1.5	-6.1	tRNA (guanine(26)-N(2))-dimethyltransferase
MMP_RS00110		-1.4	-3.6	hypothetical protein
MMP_RS06730		-1.4	-2.5	phosphopantothenate/pantothenate synthetase
MMP_RS01545		-1.4	-1.5	CBS domain-containing protein
MMP_RS05430		-1.4	-4.8	TIGR00288 family NYN domain-containing protein
MMP_RS00695		-1.4	-1.3	biotin--[acetyl-CoA-carboxylase] ligase
MMP_RS05555		-1.4	-1.7	DUF4040 domain-containing protein
MMP_RS01085		-1.4	-2.8	hypothetical protein
MMP_RS06895		-1.4	-2.8	selenocysteine-specific translation elongation factor
MMP_RS08940		-1.4	-1.9	MetS family NSS transporter small subunit
MMP_RS05510		-1.4	-5.1	Rrf2 family transcriptional regulator
MMP_RS05245		-1.4	-7.6	archaeosine biosynthesis radical SAM protein RaSEA
MMP_RS08210		-1.4	-1.5	phosphatidylglycerophosphatase A
MMP_RS06930		-1.4	-7.4	MBL fold metallo-hydrolase
MMP_RS06175		-1.4	-5.6	winged helix-turn-helix transcriptional regulator
MMP_RS00060		-1.3	-1.8	3-dehydroquinate synthase II
MMP_RS06200		-1.3	-8.9	M24 family metallopeptidase
MMP_RS01725		-1.3	-4.2	class I SAM-dependent methyltransferase family protein
MMP_RS06625		-1.3	-2.1	DNA primase
MMP_RS01325		-1.3	-2.6	dihydroneopterin aldolase family protein
MMP_RS07365		-1.3	-9.1	2-phosphoglycerate kinase
MMP_RS02190		-1.3	-4.4	sulfopyruvate decarboxylase subunit alpha
MMP_RS01365		-1.3	-3.7	archaeal proteasome endopeptidase complex subunit alpha
MMP_RS03580		-1.3	-4.7	signal recognition particle-docking protein FtsY
MMP_RS03205		-1.2	-2.2	peptidyl-tRNA hydrolase Pth2
MMP_RS02345		-1.2	-3.1	GTP-dependent dephospho-CoA kinase family protein
MMP_RS00305		-1.2	-1.6	phosphoribosyl-ATP diphosphatase
MMP_RS07195		-1.2	-6.0	M20 family metallo-hydrolase
MMP_RS00130		-1.2	-1.7	nickel-responsive transcriptional regulator NikR
MMP_RS06120		-1.2	-2.1	UPF0147 family protein
MMP_RS07200		-1.2	-4.9	[5-(aminomethyl)furan-3-yl]methyl phosphate kinase
MMP_RS05875		-1.2	-3.6	hydroxyethylthiazole kinase
MMP_RS00915		-1.1	-4.2	DUF116 domain-containing protein
MMP_RS06885		-1.1	-2.1	50S ribosome-binding GTPase
MMP_RS03485		-1.1	-4.0	TIGR00267 family protein
MMP_RS00295		-1.1	-2.2	gamma carbonic anhydrase family protein
MMP_RS08320		-1.1	-4.6	molybdopterin molybdotransferase MoeA
MMP_RS06925		-1.0	-2.5	ribonuclease VapC4
MMP_RS05845		-1.0	-2.0	tRNA-intron lyase
MMP_RS05815		-1.0	-1.9	NOL1/NOP2/sun family putative RNA methylase
MMP_RS08690		-1.0	-6.3	RNA-guided pseudouridylation complex pseudouridine synthase subunit Cbf5
MMP_RS05545		-1.0	-3.6	pyridoxal phosphate-dependent aminotransferase
MMP_RS07535		-1.0	-7.0	4Fe-4S binding protein
MMP_RS07605		-1.0	-3.3	diadenylate cyclase
MMP_RS06400		-1.0	-1.9	4Fe-4S binding protein
MMP_RS02930		-1.0	-3.6	class I SAM-dependent methyltransferase
MMP_RS08200		-1.0	-8.1	archaeosine synthase subunit alpha
MMP_RS05920		-1.0	-0.4	50S ribosomal protein L37e
MMP_RS05550		-1.0	-0.8	cation:proton antiporter
MMP_RS08650		-1.0	-1.8	glutamine--fructose-6-phosphate transaminase (isomerizing)
MMP_RS00515		-1.0	-0.8	DUF655 domain-containing protein
MMP_RS02875		-1.0	-5.0	chorismate pyruvate-lyase family protein
MMP_RS03250		-1.0	-4.0	MJ1244 family protein
MMP_RS02340		-1.0	-2.0	DNA-directed RNA polymerase subunit E''
MMP_RS03700		-0.9	-5.4	sodium:proton antiporter
MMP_RS07005		-0.9	-0.7	4Fe-4S binding protein
MMP_RS03550		-0.9	-1.7	DUF2124 domain-containing protein
MMP_RS06940		-0.9	-2.4	polyprenyl diphosphate synthase
MMP_RS08165		-0.9	-1.3	phosphoglycerate dehydrogenase
MMP_RS00555		-0.9	-3.7	MFS transporter
MMP_RS00050		-0.9	-4.8	AarF/UbiB family protein
MMP_RS07710		-0.9	-4.6	cell division protein FtsZ
MMP_RS07775		-0.9	-3.6	alanine dehydrogenase
MMP_RS02245		-0.9	-2.6	hypothetical protein
MMP_RS07750		-0.9	-3.6	DUF357 domain-containing protein
MMP_RS01840		-0.9	-4.3	TIGR00289 family protein
MMP_RS04090		-0.9	-1.4	hypothetical protein
MMP_RS05250		-0.9	-1.7	NFYB/HAP3 family transcription factor subunit
MMP_RS06915		-0.9	-3.5	metallophosphoesterase
MMP_RS06865		-0.8	-1.3	HypC/HybG/HupF family hydrogenase formation chaperone
MMP_RS07390		-0.8	-1.4	cell division protein FtsZ
MMP_RS03080		-0.8	-2.1	universal stress protein
MMP_RS03095		-0.8	-3.5	diphthine synthase
MMP_RS01830		-0.8	-1.1	tRNA-Val
MMP_RS04125		-0.8	-2.5	TetR/AcrR family transcriptional regulator
MMP_RS02135		-0.8	-2.2	DUF5612 domain-containing protein
MMP_RS06340		-0.8	-4.2	phosphoadenosine phosphosulfate reductase family protein
MMP_RS08615		-0.8	-2.2	flagellar protein G
MMP_RS00290		-0.8	-4.5	hypothetical protein
MMP_RS02170		-0.8	-4.7	CBS domain-containing protein
MMP_RS02145		-0.8	-3.6	winged helix-turn-helix transcriptional regulator
MMP_RS09055		-0.8	-1.0	CAP domain-containing protein
MMP_RS01180		-0.8	-1.1	XTP/dITP diphosphatase
MMP_RS06855		-0.8	-5.6	hypothetical protein
MMP_RS01240		-0.8	-0.7	7-cyano-7-deazaguanine synthase QueC
MMP_RS07580		-0.8	-1.7	DUF356 domain-containing protein
MMP_RS06670		-0.8	-2.8	glucose-6-phosphate isomerase
MMP_RS03155		-0.8	-3.6	precorrin-6A reductase
MMP_RS03445		-0.8	-0.8	methanogenesis marker 17 protein
MMP_RS07385		-0.8	-1.0	protein translocase SEC61 complex subunit gamma
MMP_RS07435		-0.8	-1.7	GMP synthase subunit A
MMP_RS00985		-0.8	-3.4	CDC48 family AAA ATPase
MMP_RS07755		-0.7	-1.2	DUF555 domain-containing protein
MMP_RS08595		-0.7	-0.8	flagellar protein C
MMP_RS03590		-0.7	-3.4	METTL5 family protein
MMP_RS05285		-0.7	-2.8	MMPL family transporter
MMP_RS03520		-0.7	-1.5	YwbE family protein
MMP_RS07790		-0.7	-4.1	segregation/condensation protein A
MMP_RS07860		-0.7	-0.8	hypothetical protein
MMP_RS03555		-0.7	-4.1	transcriptional regulator

Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in iron experiments

For iron Iron (II) chloride tetrahydrate across organisms