Experiment set7IT052 for Phaeobacter inhibens DSM 17395

Compare to:

marine broth with Doxycycline hyclate 0.002 mg/ml

200 most detrimental genes:

  gene name fitness t score description  
PGA1_c23720 +3.6 10.6 glutathione reductase Gor compare
PGA1_c04510 +1.9 14.3 Protein of unknown function (DUF3307). compare
PGA1_c17050 +1.3 3.8 N-acetyl-gamma-glutamyl-phosphate reductase ArgC compare
PGA1_c04420 +1.3 10.8 putative glutathione transport system permease protein GsiD compare
PGA1_c02050 +1.3 5.3 acetylglutamate kinase ArgB compare
PGA1_c06670 +1.2 5.4 carbamoyl-phosphate synthase small chain compare
PGA1_c06420 +1.2 5.1 acetyltransferase domain-containing protein compare
PGA1_c11710 +1.2 7.8 transcriptional regulator, LysR family compare
PGA1_c24560 +1.2 8.0 carbamoyl-phosphate synthase large chain compare
PGA1_c08600 +1.2 9.2 diguanylate cyclase (GGDEF) domain-containing protein compare
PGA1_c04450 +1.1 9.8 glutathione import ATP-binding protein GsiA compare
PGA1_c08590 +1.1 7.6 heme NO binding domain-containing protein compare
PGA1_c04440 +1.1 9.9 putative extracellular solute-binding protein compare
PGA1_65p00070 +1.1 3.4 putative regulatory protein, LuxR family compare
PGA1_c04430 +1.1 9.1 putative peptide permease protein compare
PGA1_c33190 +1.1 6.8 putative anti-sigma-B factor antagonist compare
PGA1_c24230 +1.0 6.6 acetylornithine aminotransferase ArgD compare
PGA1_c34890 +0.9 7.1 putative histidine-containing phosphotransfer protein compare
PGA1_c34880 +0.9 7.7 putative response regulator compare
PGA1_c07710 +0.9 2.8 putative sulfopyruvate decarboxylase subunit alpha compare
PGA1_78p00340 +0.8 1.8 Uncharacterized protein, possibly involved in utilization of glycolate and propanediol compare
PGA1_c31270 +0.8 7.8 putative glycosyltransferase / polysaccharide deacetylase compare
PGA1_78p00270 +0.8 2.5 lipoyl synthase LipA compare
PGA1_c23690 +0.8 5.4 protease do compare
PGA1_c31780 +0.8 2.6 DNA polymerase I compare
PGA1_c24220 +0.8 2.8 ornithine carbamoyltransferase ArgF compare
PGA1_c31260 +0.8 7.6 Protein of unknown function (DUF3131). compare
PGA1_c35770 +0.8 1.3 putative flagella basal body P-ring formation protein FlgA compare
PGA1_c30310 +0.8 3.7 Uncharacterized protein conserved in bacteria compare
PGA1_65p00030 +0.8 2.9 putative type I secretion system ATPase compare
PGA1_c20280 +0.8 2.4 penicillin-binding protein 1A MrcA compare
PGA1_c02460 +0.8 6.7 hypothetical protein compare
PGA1_c13430 +0.7 4.1 C4-dicarboxylate transport sensor protein DctB compare
PGA1_c35170 +0.7 1.1 DNA polymerase III subunit epsilon compare
PGA1_c11400 +0.7 4.0 ferric uptake regulation protein Fur compare
PGA1_c35920 +0.7 2.3 thiamine kinase ThiK-like protein compare
PGA1_c02430 +0.7 5.5 type I secretion membrane fusion protein, HlyD family compare
PGA1_c02440 +0.7 5.8 putative ATP-binding/permease fusion ABC transporter compare
PGA1_c33600 +0.7 1.3 hypothetical protein compare
PGA1_c15380 +0.7 1.6 Uncharacterized conserved protein compare
PGA1_262p01110 +0.7 3.1 hypothetical protein compare
PGA1_c13530 +0.7 3.2 hypothetical protein compare
PGA1_c10730 +0.6 2.6 ribose-5-phosphate isomerase B compare
PGA1_c02450 +0.6 5.3 putative outer membrane efflux protein compare
PGA1_c18490 +0.6 5.7 Predicted ATPase compare
PGA1_c21900 +0.6 1.6 Uncharacterized conserved small protein compare
PGA1_c18380 +0.6 1.1 Phage Head-Tail Attachment. compare
PGA1_c04200 +0.6 2.9 phosphate uptake ABC transporter permease protein PhoE compare
PGA1_c16210 +0.6 2.4 iron-sulfur cluster binding domain-containing protein compare
PGA1_c18480 +0.6 5.5 hypothetical protein compare
PGA1_c19200 +0.6 1.7 Predicted Fe-S protein compare
PGA1_c35370 +0.6 4.5 sensor histidine kinase RegB compare
PGA1_c19870 +0.6 2.1 hypothetical protein compare
PGA1_c14800 +0.6 1.3 nitrogen regulation protein NtrY compare
PGA1_c15750 +0.6 1.8 phosphate import ATP-binding protein PstB compare
PGA1_78p00210 +0.6 1.1 putative oxidoreductase compare
PGA1_c03330 +0.6 2.3 tetratricopeptide repeat-containing protein compare
PGA1_c14190 +0.5 3.7 putative transcriptional regulator, AraC family compare
PGA1_c17030 +0.5 1.8 peptidoglycan binding domain-containing protein compare
PGA1_c02700 +0.5 3.7 putative HTH-type transcriptional regulator compare
PGA1_c02390 +0.5 2.2 transcriptional regulator, MerR family compare
PGA1_65p00150 +0.5 1.4 Protein of unknown function (DUF2886). compare
PGA1_262p01250 +0.5 1.3 transcriptional regulator, crp family compare
PGA1_c12390 +0.5 2.1 putative protein SoxS compare
PGA1_262p00130 +0.5 2.6 hypothetical protein compare
PGA1_262p01000 +0.5 2.3 dipeptide transport ATP-binding protein DppF compare
PGA1_c09580 +0.5 2.2 antibiotic biosynthesis monooxygenase-like protein compare
PGA1_262p01490 +0.5 1.5 putative sarcosine oxidase, gamma subunit compare
PGA1_c07950 +0.5 1.0 hypothetical protein compare
PGA1_c36020 +0.5 1.5 putative 3'-5'-exonuclease compare
PGA1_c10060 +0.5 1.3 putative transcriptional regulator, MerR family compare
PGA1_c05390 +0.5 2.5 glycosyl transferase compare
PGA1_65p00310 +0.5 1.8 GDP-mannose 4,6-dehydratase Gmd compare
PGA1_262p00450 +0.5 1.2 glucose transporter, ATPase component (from data) compare
PGA1_c14530 +0.5 1.3 transcriptional regulator, TetR family compare
PGA1_262p00570 +0.5 1.8 hypothetical protein compare
PGA1_c08780 +0.5 1.5 hypothetical protein compare
PGA1_c34590 +0.5 2.9 putative peptidylprolyl isomerase compare
PGA1_c15040 +0.5 2.7 Uncharacterized conserved protein compare
PGA1_c04900 +0.5 2.0 peptidyl-tRNA hydrolase Pth compare
PGA1_c31880 +0.5 4.4 signal transduction histidine kinase compare
PGA1_c18340 +0.5 1.9 putative baseplate assembly protein W compare
PGA1_c06980 +0.5 1.0 hypothetical protein compare
PGA1_c29780 +0.5 3.1 3-isopropylmalate dehydratase large subunit compare
PGA1_c05250 +0.5 3.0 2-keto-3-deoxy-galactonokinase compare
PGA1_c10870 +0.5 2.5 conserved hypothetical integral membrane protein compare
PGA1_262p01390 +0.5 0.9 hypothetical protein compare
PGA1_c01260 +0.5 0.8 putative cobalamin adenosyltransferase compare
PGA1_c12570 +0.5 2.2 ABC-type transport system involved in resistance to organic solvents, periplasmic component compare
PGA1_c29360 +0.5 2.2 VacJ-like lipoprotein compare
PGA1_c10860 +0.5 3.6 putative ABC transporter, ATP binding protein compare
PGA1_262p01670 +0.5 2.5 putative transcriptional regulator, LysR family compare
PGA1_c29620 +0.5 1.8 putative CDP-diacylglycerol--serine O-phosphatidyltransferase compare
PGA1_c20590 +0.5 1.3 hypothetical protein compare
PGA1_c09290 +0.4 1.9 WGR domain. compare
PGA1_262p00920 +0.4 1.5 Membrane proteins related to metalloendopeptidases compare
PGA1_65p00270 +0.4 1.8 Hemolysin-type calcium-binding repeat (2 copies). compare
PGA1_c21800 +0.4 2.3 putative transporter compare
PGA1_c14540 +0.4 1.9 putative polyphosphate kinase 2 compare
PGA1_c01100 +0.4 1.5 Heat shock protein compare
PGA1_c09470 +0.4 2.6 putative ATP-binding protein compare
PGA1_c29370 +0.4 1.4 putative toluene tolerance protein, Ttg2 family compare
PGA1_c11120 +0.4 2.3 putative deoxyguanosinetriphosphate triphosphohydrolase compare
PGA1_c02030 +0.4 1.2 phosphoglycerate mutase-like protein compare
PGA1_c12990 +0.4 2.6 Peptidase propeptide and YPEB domain. compare
PGA1_c23710 +0.4 1.2 putative protein HflK compare
PGA1_c12550 +0.4 1.5 hypothetical protein compare
PGA1_262p00250 +0.4 1.6 ferritin-like protein compare
PGA1_262p00310 +0.4 1.1 glutathione transport system permease protein GsiC compare
PGA1_c14270 +0.4 1.4 hypothetical protein compare
PGA1_c19010 +0.4 1.6 Uncharacterized protein conserved in bacteria compare
PGA1_c10590 +0.4 1.0 putative ATP-dependent RNA helicase RhlE compare
PGA1_c21000 +0.4 1.8 Predicted integral membrane protein (DUF2282). compare
PGA1_c03290 +0.4 1.9 transcription elongation factor GreA compare
PGA1_c23000 +0.4 1.3 hypothetical protein compare
PGA1_c22820 +0.4 1.4 lytic transglycosylase-like protein compare
PGA1_262p00280 +0.4 1.8 putative proline racemase compare
PGA1_c09450 +0.4 1.6 DNA helicase II UvrD compare
PGA1_262p00610 +0.4 0.7 metallophosphoesterase compare
PGA1_262p00710 +0.4 0.9 serine/threonine-protein kinase RsbT-like protein compare
PGA1_262p01330 +0.4 0.8 transcriptional regulator, MarR family compare
PGA1_c05530 +0.4 1.4 putative allantoin catabolism protein compare
PGA1_262p00160 +0.4 1.8 Branched-chain amino acid transport protein (AzlD). compare
PGA1_c11410 +0.4 2.2 putative integral membrane protein compare
PGA1_c15290 +0.4 1.0 Lactoylglutathione lyase and related lyases compare
PGA1_c03170 +0.4 2.1 hypothetical protein compare
PGA1_78p00540 +0.4 0.9 hypothetical protein compare
PGA1_262p01320 +0.4 0.8 Uncharacterized protein conserved in bacteria compare
PGA1_c17740 +0.4 2.3 putative gene transfer agent protein compare
PGA1_c13700 +0.4 1.7 hypothetical protein compare
PGA1_c32110 +0.4 1.0 hypothetical protein compare
PGA1_c34650 +0.4 0.5 UPF0090 protein YhbC compare
PGA1_262p01130 +0.4 0.9 hypothetical protein compare
PGA1_c20130 +0.4 2.1 RDD family. compare
PGA1_c14640 +0.4 1.4 hypothetical protein compare
PGA1_c21010 +0.4 2.1 component of stress sensing system, with PGA1_c21020 (DUF2063) (from data) compare
PGA1_c22270 +0.4 1.5 Protein of unknown function (DUF1353). compare
PGA1_c30570 +0.4 1.2 Predicted metal-dependent hydrolase compare
PGA1_c13850 +0.4 1.9 SnoaL-like polyketide cyclase. compare
PGA1_c04600 +0.4 2.3 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) compare
PGA1_c25960 +0.4 1.8 putative biopolymer transport protein compare
PGA1_262p02370 +0.4 1.7 putative histidine transport system permease protein HisQ compare
PGA1_c17800 +0.3 1.0 putative gene transfer agent head-tail adaptor compare
PGA1_c21530 +0.3 1.3 hypothetical protein compare
PGA1_c16440 +0.3 1.6 MFS transporter compare
PGA1_c10130 +0.3 1.9 glutathione import ATP-binding protein GsiA compare
PGA1_c17700 +0.3 1.3 hypothetical protein compare
PGA1_c31760 +0.3 1.0 Uncharacterized protein conserved in bacteria compare
PGA1_c20000 +0.3 1.1 hypothetical protein compare
PGA1_262p01300 +0.3 1.1 Cupin domain. compare
PGA1_c02970 +0.3 1.4 hypothetical protein compare
PGA1_c16780 +0.3 1.4 Uncharacterized conserved protein compare
PGA1_c12420 +0.3 1.3 cytochrome c SoxX compare
PGA1_65p00060 +0.3 1.1 putative regulatory protein, LuxR family compare
PGA1_c16010 +0.3 2.4 putative L,D-transpeptidase compare
PGA1_262p00060 +0.3 1.5 putative glycosyl transferase compare
PGA1_c31580 +0.3 1.3 putative HTH-type transcriptional regulator, TetR family compare
PGA1_c35260 +0.3 1.3 ATP-dependent protease HslV compare
PGA1_c20140 +0.3 2.0 putative arginine-tRNA-protein transferase compare
PGA1_c21640 +0.3 1.4 hypothetical protein compare
PGA1_c22180 +0.3 2.0 long-chain-fatty-acid--CoA ligase FadD compare
PGA1_c05300 +0.3 2.3 putative glycosyl transferase compare
PGA1_c26010 +0.3 1.4 transcriptional regulator, MarR family compare
PGA1_262p00240 +0.3 1.1 Protein of unknown function (DUF1289). compare
PGA1_c29540 +0.3 1.0 hypothetical protein compare
PGA1_c04010 +0.3 1.0 putative universal stress protein compare
PGA1_c15760 +0.3 1.6 putative phosphate transport system permease protein PstA compare
PGA1_c05490 +0.3 1.8 ureidoglycolate hydrolase AllA compare
PGA1_c36240 +0.3 2.2 ribosomal RNA large subunit methyltransferase N compare
PGA1_c02320 +0.3 2.5 GDP-mannose 4,6-dehydratase Gmd compare
PGA1_c00050 +0.3 1.7 putative transcriptional regulator, tetR family compare
PGA1_c13750 +0.3 1.2 phosphopantetheine binding protein compare
PGA1_78p00030 +0.3 0.6 putative multicopper oxidase compare
PGA1_c33060 +0.3 2.0 glyoxalase-like protein compare
PGA1_c07465 +0.3 2.0 putative dksA/traR C4-type zinc finger protein compare
PGA1_262p01370 +0.3 1.8 putative dioxygenase compare
PGA1_65p00420 +0.3 1.0 putative ABC type transporter compare
PGA1_c05290 +0.3 2.5 polysaccharide biosynthesis protein ExoT-like protein compare
PGA1_262p02320 +0.3 1.9 putative acetolactate synthase isozyme 1 large subunit compare
PGA1_c12700 +0.3 1.5 hypothetical protein compare
PGA1_c05410 +0.3 2.1 hypothetical protein compare
PGA1_c24410 +0.3 1.1 hypothetical protein compare
PGA1_c22670 +0.3 1.2 hypothetical protein compare
PGA1_c24140 +0.3 1.8 protein-tyrosine phosphatase compare
PGA1_c17870 +0.3 1.3 hypothetical protein compare
PGA1_c08480 +0.3 1.1 NUDIX hydrolase-like protein compare
PGA1_c33860 +0.3 1.8 tRNA-Arg compare
PGA1_c31810 +0.3 2.0 Uncharacterized protein conserved in bacteria compare
PGA1_c35330 +0.3 1.8 nucleotidyl transferase-like protein compare
PGA1_c24980 +0.3 1.6 maoC like domain-containing protein compare
PGA1_c10840 +0.3 1.8 DNA repair protein RadA compare
PGA1_c30170 +0.3 2.6 ABC transporter permease protein compare
PGA1_c09410 +0.3 0.5 hypothetical protein compare
PGA1_262p01770 +0.3 1.3 putative endoribonuclease compare
PGA1_c12030 +0.3 1.9 3-ketoacyl-CoA thiolase FadA compare
PGA1_c06940 +0.3 2.3 putative adenosylcobalamin(B12)-dependent ribonucleotide reductases compare
PGA1_c03770 +0.3 1.0 hypothetical protein compare
PGA1_78p00150 +0.3 0.7 putative HTH-type transcriptional regulator compare
PGA1_c13510 +0.3 1.0 hypothetical protein compare
PGA1_c27060 +0.3 0.9 putative signal transduction histidine kinase compare


Specific Phenotypes

For 5 genes in this experiment

For stress Doxycycline hyclate in Phaeobacter inhibens DSM 17395

For stress Doxycycline hyclate across organisms