Experiment set7IT051 for Phaeobacter inhibens DSM 17395

Compare to:

marine broth with D-Cycloserine 0.0625 mg/ml

200 most detrimental genes:

  gene name fitness t score description  
PGA1_c08600 +1.3 10.7 diguanylate cyclase (GGDEF) domain-containing protein compare
PGA1_c11710 +1.2 7.0 transcriptional regulator, LysR family compare
PGA1_c34880 +1.2 10.3 putative response regulator compare
PGA1_c33190 +1.1 6.5 putative anti-sigma-B factor antagonist compare
PGA1_c02050 +1.1 4.4 acetylglutamate kinase ArgB compare
PGA1_c24220 +1.1 4.2 ornithine carbamoyltransferase ArgF compare
PGA1_c08590 +1.0 7.4 heme NO binding domain-containing protein compare
PGA1_c34890 +1.0 8.0 putative histidine-containing phosphotransfer protein compare
PGA1_c24230 +1.0 6.9 acetylornithine aminotransferase ArgD compare
PGA1_262p00980 +1.0 6.9 transcriptional regulator, LysR family compare
PGA1_c17050 +0.9 3.6 N-acetyl-gamma-glutamyl-phosphate reductase ArgC compare
PGA1_65p00180 +0.9 3.3 putative sugar transferase compare
PGA1_c14800 +0.9 1.7 nitrogen regulation protein NtrY compare
PGA1_c06420 +0.9 3.0 acetyltransferase domain-containing protein compare
PGA1_c19200 +0.8 2.8 Predicted Fe-S protein compare
PGA1_c03880 +0.8 7.4 putative transcriptional activator protein RaiR compare
PGA1_c12390 +0.8 1.7 putative protein SoxS compare
PGA1_c19140 +0.8 3.3 sarcosine oxidase-like protein compare
PGA1_c07710 +0.8 1.7 putative sulfopyruvate decarboxylase subunit alpha compare
PGA1_c04670 +0.8 4.5 putative metal ion uptake regulator compare
PGA1_c15020 +0.7 3.8 D-beta-hydroxybutyrate dehydrogenase BdhA compare
PGA1_c20320 +0.7 2.3 Protein-disulfide isomerase compare
PGA1_262p01250 +0.7 1.8 transcriptional regulator, crp family compare
PGA1_c16450 +0.7 1.7 Phytoene/squalene synthetase compare
PGA1_c17680 +0.7 1.8 hypothetical protein compare
PGA1_c31880 +0.7 6.5 signal transduction histidine kinase compare
PGA1_c20140 +0.7 3.9 putative arginine-tRNA-protein transferase compare
PGA1_78p00060 +0.7 2.1 Uncharacterized protein conserved in bacteria compare
PGA1_c29620 +0.7 3.3 putative CDP-diacylglycerol--serine O-phosphatidyltransferase compare
PGA1_c02430 +0.7 4.8 type I secretion membrane fusion protein, HlyD family compare
PGA1_78p00140 +0.7 1.2 Sugar phosphate isomerases/epimerases compare
PGA1_c02440 +0.7 5.6 putative ATP-binding/permease fusion ABC transporter compare
PGA1_c02520 +0.7 5.5 copper-transporting P-type ATPase ActP compare
PGA1_65p00450 +0.6 2.6 UDP-glucose 6-dehydrogenase Ugd compare
PGA1_c23690 +0.6 4.6 protease do compare
PGA1_c14190 +0.6 4.0 putative transcriptional regulator, AraC family compare
PGA1_c03180 +0.6 2.1 hypothetical protein compare
PGA1_c31930 +0.6 5.0 putative transporter, MFS family compare
PGA1_c02460 +0.6 5.3 hypothetical protein compare
PGA1_c12550 +0.6 2.2 hypothetical protein compare
PGA1_262p00900 +0.6 1.2 ABC transporter, ATP-binding protein compare
PGA1_c06000 +0.6 2.3 chorismate mutase-like protein compare
PGA1_c02450 +0.6 4.9 putative outer membrane efflux protein compare
PGA1_c11410 +0.6 2.9 putative integral membrane protein compare
PGA1_c34400 +0.6 3.5 aminotransferase class-III compare
PGA1_c13510 +0.6 1.1 hypothetical protein compare
PGA1_c14500 +0.6 4.7 transcriptional regulator, GntR family compare
PGA1_262p02230 +0.6 1.1 zinc uptake regulation protein zur-like protein compare
PGA1_c15100 +0.6 2.9 tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ compare
PGA1_262p00910 +0.6 2.2 putative cation transort protein compare
PGA1_c10910 +0.6 3.8 dihydroorotase PyrC compare
PGA1_c02030 +0.6 1.7 phosphoglycerate mutase-like protein compare
PGA1_c25130 +0.5 2.6 Methylase involved in ubiquinone/menaquinone biosynthesis compare
PGA1_c07920 +0.5 3.6 signal transduction histidine kinase compare
PGA1_c15590 +0.5 4.7 putative transcriptional activator protein compare
PGA1_c20530 +0.5 2.7 putative transcriptional regulator compare
PGA1_c17800 +0.5 1.2 putative gene transfer agent head-tail adaptor compare
PGA1_c18520 +0.5 2.0 Uncharacterized protein conserved in bacteria compare
PGA1_c05840 +0.5 0.9 Uncharacterized conserved small protein compare
PGA1_c34410 +0.5 3.6 HTH-type transcriptional regulator, GntR family compare
PGA1_c14640 +0.5 2.2 hypothetical protein compare
PGA1_c21650 +0.5 1.8 Uncharacterized protein conserved in bacteria compare
PGA1_c06670 +0.5 1.5 carbamoyl-phosphate synthase small chain compare
PGA1_262p00450 +0.5 1.8 glucose transporter, ATPase component (from data) compare
PGA1_c15330 +0.5 2.1 hypothetical protein compare
PGA1_c28980 +0.5 2.9 glyoxalase/bleomycin resistance protein/dioxygenase domain-containing protein compare
PGA1_c17160 +0.5 1.8 Stress-induced morphogen (activity unknown) compare
PGA1_c27060 +0.5 1.9 putative signal transduction histidine kinase compare
PGA1_c13620 +0.4 1.9 hypothetical protein compare
PGA1_c36270 +0.4 1.0 hypothetical protein compare
PGA1_c11390 +0.4 1.5 putative ATP-dependent RNA helicase RhlE compare
PGA1_c07510 +0.4 3.6 DNA/RNA helicase-like protein compare
PGA1_c29060 +0.4 0.9 HTH-type transcriptional regulator PecS compare
PGA1_c32030 +0.4 2.9 glycerol kinase GlpK compare
PGA1_c34650 +0.4 1.0 UPF0090 protein YhbC compare
PGA1_c26950 +0.4 1.7 putative exopolysaccharide synthesis protein ExoD compare
PGA1_262p00660 +0.4 1.3 Predicted periplasmic protein compare
PGA1_262p00870 +0.4 2.1 ABC transporter, extracellular solute-binding protein compare
PGA1_262p01540 +0.4 1.0 putative enoyl-CoA hydratase / isomerase compare
PGA1_c10030 +0.4 2.8 NAD(P) transhydrogenase subunit alpha compare
PGA1_c15040 +0.4 2.5 Uncharacterized conserved protein compare
PGA1_c12030 +0.4 2.2 3-ketoacyl-CoA thiolase FadA compare
PGA1_c03770 +0.4 2.0 hypothetical protein compare
PGA1_c34990 +0.4 3.2 NADP-dependent malic enzyme compare
PGA1_c20690 +0.4 2.9 C4-dicarboxylate transport transcriptional regulatory protein DctD compare
PGA1_c06630 +0.4 1.7 hypothetical protein compare
PGA1_c10040 +0.4 2.9 NAD(P) transhydrogenase subunit beta compare
PGA1_c17170 +0.4 1.4 hypothetical protein compare
PGA1_c03290 +0.4 1.8 transcription elongation factor GreA compare
PGA1_c27110 +0.4 2.2 Protein of unknown function (DUF1328). compare
PGA1_c31180 +0.4 2.1 Uncharacterized protein conserved in bacteria compare
PGA1_262p00330 +0.4 2.2 oligopeptide ABC transporter, ATP binding protein compare
PGA1_65p00150 +0.4 1.5 Protein of unknown function (DUF2886). compare
PGA1_c04940 +0.4 2.4 Lipid A 3-O-deacylase (PagL). compare
PGA1_c12150 +0.4 2.9 dihydroorotate dehydrogenase PyrD compare
PGA1_c12440 +0.4 1.1 sulphur oxidation protein SoxZ compare
PGA1_78p00150 +0.4 1.1 putative HTH-type transcriptional regulator compare
PGA1_262p00770 +0.4 0.8 putative lytic murein transglycosylase compare
PGA1_c15660 +0.4 2.5 enoyl-CoA hydratase/isomerase family protein compare
PGA1_c06160 +0.4 1.7 hypothetical protein compare
PGA1_c04960 +0.4 2.8 putative non-specific ribonucleoside hydrolase compare
PGA1_c35410 +0.4 1.8 hypothetical protein compare
PGA1_78p00540 +0.4 0.9 hypothetical protein compare
PGA1_c09420 +0.4 3.4 pyruvate carboxylase Pyc compare
PGA1_c05560 +0.4 1.3 glycine cleavage system protein GcvH compare
PGA1_c16190 +0.4 1.4 hypothetical protein compare
PGA1_c10020 +0.4 1.7 Putative protein-S-isoprenylcysteine methyltransferase compare
PGA1_c31620 +0.4 2.2 Uncharacterized protein conserved in bacteria compare
PGA1_c20150 +0.4 2.4 glyoxalase-like protein compare
PGA1_c10210 +0.4 1.6 hypothetical protein compare
PGA1_c15050 +0.4 1.2 Uncharacterized enzyme involved in pigment biosynthesis compare
PGA1_c03260 +0.4 2.3 hypothetical protein compare
PGA1_262p00270 +0.4 1.0 transcriptional regulator, GntR family compare
PGA1_c09580 +0.4 1.5 antibiotic biosynthesis monooxygenase-like protein compare
PGA1_c10090 +0.4 1.9 YeeE/YedE family (DUF395). compare
PGA1_c34850 +0.4 1.4 putative NUDIX hydrolase compare
PGA1_c14270 +0.4 1.7 hypothetical protein compare
PGA1_262p00950 +0.4 1.4 thioesterase superfamily protein TdaD compare
PGA1_c17750 +0.4 2.1 putative gene transfer agent tail tape measure protein compare
PGA1_c13750 +0.4 1.4 phosphopantetheine binding protein compare
PGA1_262p00260 +0.4 1.5 hypothetical protein compare
PGA1_c28320 +0.4 2.0 ABC transporter, ATP-binding protein compare
PGA1_c31270 +0.4 3.3 putative glycosyltransferase / polysaccharide deacetylase compare
PGA1_c12420 +0.4 2.0 cytochrome c SoxX compare
PGA1_c23560 +0.4 2.0 Membrane transporters of cations and cationic drugs compare
PGA1_c05470 +0.4 0.5 hydroxyisourate hydrolase compare
PGA1_c19050 +0.4 0.8 hypothetical protein compare
PGA1_c03530 +0.3 1.5 pyridoxamine 5'-phosphate oxidase-like protein compare
PGA1_c03700 +0.3 1.3 Uncharacterized conserved small protein compare
PGA1_c28020 +0.3 2.4 fructokinase Frk compare
PGA1_c19180 +0.3 1.0 cytochrome c-type biogenesis protein CycH compare
PGA1_c33430 +0.3 2.0 glutathione S-transferase-like protein compare
PGA1_65p00280 +0.3 1.1 Protein of unknown function (DUF2793)./Domain of unknown function (DUF3476). compare
PGA1_c29120 +0.3 0.9 hypothetical protein compare
PGA1_c13640 +0.3 1.4 Phosphopantetheine attachment site. compare
PGA1_262p00610 +0.3 0.4 metallophosphoesterase compare
PGA1_c24060 +0.3 1.5 Predicted small secreted protein compare
PGA1_c22500 +0.3 1.1 hypothetical protein compare
PGA1_262p00050 +0.3 1.8 putative glycosyl transferase compare
PGA1_262p01410 +0.3 0.6 malate/L-lactate dehydrogenase-like protein compare
PGA1_262p00700 +0.3 0.6 stressosome protein rsbS-like protein compare
PGA1_78p00340 +0.3 0.7 Uncharacterized protein, possibly involved in utilization of glycolate and propanediol compare
PGA1_c08480 +0.3 1.0 NUDIX hydrolase-like protein compare
PGA1_c34710 +0.3 1.4 glutaredoxin GrxC compare
PGA1_c23730 +0.3 1.6 hypothetical protein compare
PGA1_262p00830 +0.3 1.6 hypothetical protein compare
PGA1_c11100 +0.3 1.1 Predicted membrane protein compare
PGA1_c09170 +0.3 1.8 putative biotin synthesis protein BioC compare
PGA1_c17810 +0.3 1.1 putative gene transfer agent protein compare
PGA1_c01670 +0.3 1.5 hypothetical protein compare
PGA1_262p00560 +0.3 1.2 uracil DNA glycosylase-like protein compare
PGA1_c24390 +0.3 1.5 Uncharacterized protein conserved in bacteria compare
PGA1_262p00420 +0.3 1.7 Transcriptional regulator/sugar kinase compare
PGA1_c33030 +0.3 1.8 hypothetical protein compare
PGA1_c05390 +0.3 1.8 glycosyl transferase compare
PGA1_262p01110 +0.3 0.9 hypothetical protein compare
PGA1_c04010 +0.3 0.9 putative universal stress protein compare
PGA1_c19630 +0.3 2.2 oxidoreductase, molybdopterin binding compare
PGA1_c14490 +0.3 0.7 Uncharacterized conserved small protein compare
PGA1_c29010 +0.3 1.8 putative helix-turn-helix protein compare
PGA1_c12370 +0.3 2.0 YeeE/YedE family (DUF395). compare
PGA1_78p00210 +0.3 0.9 putative oxidoreductase compare
PGA1_c04390 +0.3 1.8 Predicted glycosyl transferase compare
PGA1_c27660 +0.3 0.8 hypothetical protein compare
PGA1_c29400 +0.3 1.2 nitrogen regulatory protein P-II compare
PGA1_c10270 +0.3 2.2 hypothetical protein compare
PGA1_c31260 +0.3 2.8 Protein of unknown function (DUF3131). compare
PGA1_c08420 +0.3 2.0 putative 3-hydroxyacyl-CoA dehydrogenase compare
PGA1_c08850 +0.3 1.6 secondary thiamine-phosphate synthase enzyme compare
PGA1_262p00720 +0.3 1.2 serine/threonine-protein kinase RsbT-like protein compare
PGA1_c18390 +0.3 1.4 hypothetical protein compare
PGA1_c04150 +0.3 1.1 thioesterase domain-containing protein compare
PGA1_c04290 +0.3 1.5 phosphonates transport ATP-binding protein PhnL compare
PGA1_c12110 +0.3 1.6 thioesterase domain-containing protein compare
PGA1_262p01710 +0.3 1.5 putative glutathione transport system permease protein compare
PGA1_262p00310 +0.3 1.0 glutathione transport system permease protein GsiC compare
PGA1_c09970 +0.3 1.5 tryptophan 2,3-dioxygenase KynA compare
PGA1_c08230 +0.3 1.4 Predicted transcriptional regulators compare
PGA1_c22370 +0.3 1.4 hypothetical protein compare
PGA1_c31670 +0.3 1.2 AFG1-like ATPase compare
PGA1_c18660 +0.3 1.5 hypothetical protein compare
PGA1_c29000 +0.3 1.1 inner membrane lipoprotein compare
PGA1_262p01340 +0.3 1.3 hypothetical protein compare
PGA1_c04080 +0.3 2.0 phenylacetic acid degradation protein PaaA compare
PGA1_c32530 +0.3 2.1 CobW-like nucleotide-binding protein compare
PGA1_c29280 +0.3 1.5 peroxiredoxin compare
PGA1_c21490 +0.3 1.5 putative N-acetyltransferase compare
PGA1_c17780 +0.3 1.2 putative gene transfer agent major tail protein compare
PGA1_c06510 +0.3 2.3 pyruvate, phosphate dikinase PpdK compare
PGA1_c15790 +0.3 0.9 putative phosphate transporter, phosphate-binding protein compare
PGA1_c03220 +0.3 1.8 branched-chain amino acid transport protein azlC-like protein compare
PGA1_c36200 +0.3 1.5 Uncharacterized protein conserved in bacteria compare
PGA1_c29560 +0.3 1.6 hypothetical protein compare
PGA1_c33020 +0.3 1.7 peroxiredoxin compare
PGA1_262p00960 +0.3 2.8 Prephenate dehydratase. compare
PGA1_c20960 +0.3 1.7 carboxylesterase bioH-like protein compare
PGA1_262p00240 +0.3 1.1 Protein of unknown function (DUF1289). compare
PGA1_c34590 +0.3 1.9 putative peptidylprolyl isomerase compare
PGA1_c34110 +0.3 2.0 branched-chain-amino-acid aminotransferase IlvE compare
PGA1_262p01450 +0.3 1.3 putative membrane dipeptidase compare


Specific Phenotypes

For 10 genes in this experiment

For stress D-Cycloserine in Phaeobacter inhibens DSM 17395

For stress D-Cycloserine across organisms