Experiment set7IT041 for Klebsiella michiganensis M5al

Compare to:

LB with Nickel (II) chloride hexahydrate 1.5 mM

200 most important genes:

  gene name fitness t score description  
BWI76_RS11255 -5.1 -3.5 putrescine/spermidine ABC transporter ATP-binding protein compare
BWI76_RS05015 -4.7 -4.0 transcriptional regulator compare
BWI76_RS11240 -4.5 -6.3 spermidine/putrescine ABC transporter substrate-binding protein PotD compare
BWI76_RS01210 -4.5 -3.9 tyrosine recombinase XerC compare
BWI76_RS01115 -4.4 -5.1 dTDP-4-amino-4,6-dideoxygalactose transaminase compare
BWI76_RS01800 -4.1 -6.5 glucose-6-phosphate isomerase compare
BWI76_RS23240 -4.1 -4.8 exonuclease V subunit gamma compare
BWI76_RS00140 -4.0 -1.6 phosphate transport system regulator PhoU compare
BWI76_RS16975 -4.0 -6.0 cysteine desufuration protein SufE compare
BWI76_RS11245 -3.9 -9.8 spermidine/putrescine ABC transporter permease PotC compare
BWI76_RS26245 -3.8 -4.8 transcriptional regulator compare
BWI76_RS23230 -3.8 -2.6 exodeoxyribonuclease V subunit beta compare
BWI76_RS16980 -3.7 -5.2 bifunctional cysteine desulfurase/selenocysteine lyase compare
BWI76_RS21010 -3.7 -5.7 Negative regulator of nickel and cobalt uptake (YfgG) (from data) compare
BWI76_RS16990 -3.6 -4.6 ABC transporter ATP-binding protein compare
BWI76_RS22805 -3.6 -12.8 GTP diphosphokinase compare
BWI76_RS00875 -3.6 -8.6 DNA-binding transcriptional regulator FabR compare
BWI76_RS26460 -3.5 -4.2 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE compare
BWI76_RS06675 -3.5 -9.0 nickel/cobalt efflux protein RcnA conserved
BWI76_RS23330 -3.4 -5.5 transcriptional regulator GalR compare
BWI76_RS08605 -3.4 -4.4 phosphoglyceromutase compare
BWI76_RS11275 -3.3 -10.1 sensor protein PhoQ compare
BWI76_RS08730 -3.2 -4.9 histidine utilization repressor compare
BWI76_RS11260 -3.1 -2.5 hypothetical protein compare
BWI76_RS01125 -3.1 -5.9 4-alpha-L-fucosyltransferase compare
BWI76_RS16995 -3.1 -7.9 Fe-S cluster assembly protein SufB compare
BWI76_RS06930 -3.1 -7.4 iron export ABC transporter permease subunit FetB conserved
BWI76_RS26175 -3.1 -5.4 DeoR/GlpR family transcriptional regulator compare
BWI76_RS12090 -3.1 -4.5 HNH endonuclease compare
BWI76_RS01110 -3.0 -6.0 TDP-fucosamine acetyltransferase compare
BWI76_RS26570 -2.9 -4.3 anion permease compare
BWI76_RS09660 -2.8 -2.9 DNA translocase FtsK compare
BWI76_RS19010 -2.8 -3.8 polysaccharide pyruvyl transferase yvff compare
BWI76_RS26455 -2.8 -3.5 4-amino-4-deoxy-L-arabinose-phospho-UDP flippase compare
BWI76_RS26075 -2.8 -3.7 DNA adenine methylase compare
BWI76_RS14915 -2.8 -3.9 hypothetical protein compare
BWI76_RS08525 -2.7 -5.4 colicin transporter compare
BWI76_RS05200 -2.6 -4.0 bifunctional uridylyltransferase/uridylyl-removing protein compare
BWI76_RS26620 -2.6 -1.8 Fe-S biogenesis protein NfuA compare
BWI76_RS06925 -2.6 -9.7 iron ABC transporter ATP-binding protein FetA compare
BWI76_RS20380 -2.6 -2.1 tRNA pseudouridine(38-40) synthase TruA compare
BWI76_RS21165 -2.5 -2.4 Fe-S cluster assembly transcriptional regulator IscR compare
BWI76_RS05205 -2.5 -7.1 type I methionyl aminopeptidase conserved
BWI76_RS16490 -2.3 -3.0 glutaredoxin compare
BWI76_RS04305 -2.3 -1.6 molecular chaperone DnaJ compare
BWI76_RS24900 -2.3 -2.7 DeoR family transcriptional regulator compare
BWI76_RS04530 -2.3 -3.5 peptidylprolyl isomerase SurA compare
BWI76_RS19040 -2.3 -7.5 hypothetical protein compare
BWI76_RS06540 -2.2 -3.7 DNA-binding protein HU-beta compare
BWI76_RS19850 -2.2 -2.6 tRNA-Pro compare
BWI76_RS09970 -2.2 -6.0 porin OmpA compare
BWI76_RS17720 -2.1 -1.7 muramoyltetrapeptide carboxypeptidase compare
BWI76_RS06245 -2.1 -3.5 proline-specific permease ProY compare
BWI76_RS05005 -2.1 -3.4 polynucleotide adenylyltransferase compare
BWI76_RS01120 -2.1 -5.7 O-antigen translocase compare
BWI76_RS19050 -2.1 -10.5 NAD(P)-dependent oxidoreductase compare
BWI76_RS26425 -2.1 -9.3 zinc/cadmium/mercury/lead-transporting ATPase compare
BWI76_RS06525 -2.1 -6.7 ATP-dependent Clp protease proteolytic subunit compare
BWI76_RS27225 -2.0 -2.4 rhodanese-like domain-containing protein compare
BWI76_RS00600 -2.0 -5.3 LacI family transcriptional regulator compare
BWI76_RS08385 -2.0 -2.3 citrate (Si)-synthase compare
BWI76_RS20995 -1.9 -3.9 RNA degradosome polyphosphate kinase compare
BWI76_RS07725 -1.9 -1.5 iron-enterobactin transporter permease compare
BWI76_RS18950 -1.9 -5.8 imidazole glycerol phosphate synthase cyclase subunit compare
BWI76_RS06530 -1.9 -5.4 ATP-dependent Clp protease ATP-binding subunit ClpX compare
BWI76_RS20640 -1.9 -6.3 cysteine synthase A compare
BWI76_RS27275 -1.9 -6.4 hypothetical protein compare
BWI76_RS00225 -1.9 -6.9 16S rRNA methyltransferase G conserved
BWI76_RS20375 -1.8 -1.9 membrane protein compare
BWI76_RS25280 -1.8 -2.4 RNase adaptor protein RapZ compare
BWI76_RS26610 -1.8 -9.7 oligopeptidase A conserved
BWI76_RS18555 -1.8 -6.9 MATE family multidrug exporter compare
BWI76_RS25700 -1.8 -7.3 heavy metal-responsive transcriptional regulator compare
BWI76_RS19055 -1.8 -8.2 dTDP-4-dehydrorhamnose 3,5-epimerase compare
BWI76_RS08205 -1.7 -4.8 DNA-binding transcriptional dual regulator NagC compare
BWI76_RS15225 -1.7 -6.7 DeoR family transcriptional regulator compare
BWI76_RS25300 -1.7 -2.6 hybrid sensor histidine kinase/response regulator compare
BWI76_RS05120 -1.7 -8.3 bifunctional glycosyl transferase/transpeptidase compare
BWI76_RS00240 -1.7 -3.0 FMN-binding protein MioC compare
BWI76_RS27820 -1.7 -2.0 ilvB operon leader peptide IvbL compare
BWI76_RS20915 -1.7 -6.0 peroxiredoxin compare
BWI76_RS27450 -1.7 -3.6 ferredoxin--NADP(+) reductase compare
BWI76_RS19370 -1.7 -5.3 fructose-bisphosphate aldolase compare
BWI76_RS24100 -1.7 -2.8 YggS family pyridoxal phosphate enzyme compare
BWI76_RS18930 -1.6 -3.7 histidinol-phosphate transaminase compare
BWI76_RS01095 -1.6 -2.4 UDP-N-acetyl-D-mannosamine dehydrogenase compare
BWI76_RS08530 -1.6 -2.3 protein TolA compare
BWI76_RS15955 -1.6 -3.4 transcriptional regulator compare
BWI76_RS08520 -1.5 -3.3 colicin transporter TolQ compare
BWI76_RS22050 -1.5 -4.4 class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI compare
BWI76_RS21070 -1.5 -2.4 outer membrane protein assembly factor BamB compare
BWI76_RS25160 -1.5 -2.2 transcription elongation factor GreA compare
BWI76_RS17000 -1.5 -2.0 Fe-S cluster assembly scaffold SufA compare
BWI76_RS19035 -1.5 -6.3 dTDP-rhamnosyl transferase compare
BWI76_RS11010 -1.5 -4.2 30S ribosomal protein S5 alanine N-acetyltransferase compare
BWI76_RS26730 -1.5 -5.0 inner membrane protein YhjD compare
BWI76_RS11250 -1.5 -2.3 spermidine/putrescine ABC transporter permease PotB compare
BWI76_RS27305 -1.5 -6.9 glycosyl transferase compare
BWI76_RS27290 -1.5 -5.4 hypothetical protein compare
BWI76_RS00715 -1.5 -3.4 two-component sensor histidine kinase compare
BWI76_RS06185 -1.5 -5.2 shikimate kinase II compare
BWI76_RS02505 -1.5 -6.2 tRNA epoxyqueuosine(34) reductase QueG compare
BWI76_RS13590 -1.4 -2.5 hypothetical protein compare
BWI76_RS18985 -1.4 -9.3 LPS O-antigen ABC transporter ATP-binding protein compare
BWI76_RS20490 -1.4 -2.3 hypothetical protein compare
BWI76_RS15810 -1.4 -5.6 hypothetical protein compare
BWI76_RS01900 -1.4 -3.2 tRNA-dihydrouridine synthase A compare
BWI76_RS20785 -1.4 -1.5 ethanolamine utilization protein EutJ compare
BWI76_RS18420 -1.4 -7.3 DNA (cytosine-5-)-methyltransferase compare
BWI76_RS02580 -1.4 -1.2 23S rRNA (guanosine(2251)-2'-O)-methyltransferase compare
BWI76_RS15990 -1.4 -6.2 serine protease compare
BWI76_RS15825 -1.4 -1.0 hypothetical protein compare
BWI76_RS24075 -1.4 -1.8 glutathione synthase compare
BWI76_RS01890 -1.4 -3.7 transcriptional regulator Zur compare
BWI76_RS18990 -1.3 -9.3 ABC transporter permease compare
BWI76_RS26665 -1.3 -2.9 DNA-binding response regulator compare
BWI76_RS21450 -1.3 -2.4 23S rRNA pseudouridine(1911/1915/1917) synthase compare
BWI76_RS09760 -1.3 -4.8 3-phosphoshikimate 1-carboxyvinyltransferase compare
BWI76_RS15215 -1.3 -1.2 N-acetyltransferase compare
BWI76_RS27280 -1.3 -4.8 polymerase compare
BWI76_RS24380 -1.3 -4.2 esterase YqiA compare
BWI76_RS24400 -1.3 -5.8 outer membrane channel protein TolC compare
BWI76_RS20910 -1.3 -4.3 glycine cleavage system transcriptional repressor compare
BWI76_RS21685 -1.3 -1.3 hypothetical protein compare
BWI76_RS11155 -1.3 -2.9 penicillin-binding protein activator LpoB compare
BWI76_RS18935 -1.3 -3.4 bifunctional imidazole glycerol-phosphate dehydratase/histidinol phosphatase compare
BWI76_RS25070 -1.3 -1.7 hypothetical protein compare
BWI76_RS07475 -1.3 -1.3 DNA-binding transcriptional regulator RamA compare
BWI76_RS18385 -1.3 -1.5 hypothetical protein compare
BWI76_RS09890 -1.3 -6.0 aminopeptidase N conserved
BWI76_RS01135 -1.3 -4.0 lipopolysaccharide N-acetylmannosaminouronosyltransferase compare
BWI76_RS20330 -1.3 -3.5 histidine/lysine/arginine/ornithine ABC transporter permease HisQ compare
BWI76_RS01585 -1.3 -3.7 transcriptional regulator compare
BWI76_RS18000 -1.2 -3.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF compare
BWI76_RS21505 -1.2 -1.3 hypothetical protein compare
BWI76_RS24850 -1.2 -5.1 DeoR family transcriptional regulator compare
BWI76_RS11940 -1.2 -3.8 aconitate hydratase 1 compare
BWI76_RS15760 -1.2 -1.7 hypothetical protein compare
BWI76_RS21000 -1.2 -4.2 exopolyphosphatase compare
BWI76_RS20335 -1.2 -2.4 zinc transporter compare
BWI76_RS22060 -1.2 -7.3 ribonucleotide-diphosphate reductase subunit beta compare
BWI76_RS22055 -1.2 -6.7 ribonucleotide-diphosphate reductase compare
BWI76_RS15840 -1.2 -3.8 prophage protein compare
BWI76_RS07740 -1.2 -1.8 Fe2+-enterobactin ABC transporter substrate-binding protein compare
BWI76_RS06545 -1.2 -3.1 peptidylprolyl isomerase compare
BWI76_RS18925 -1.2 -3.6 histidinol dehydrogenase compare
BWI76_RS01630 -1.2 -1.3 16S ribosomal RNA compare
BWI76_RS01330 -1.2 -3.7 twin-arginine translocase subunit TatC compare
BWI76_RS09450 -1.1 -1.5 30S ribosomal protein S6--L-glutamate ligase compare
BWI76_RS20435 -1.1 -1.4 chorismate synthase compare
BWI76_RS08535 -1.1 -1.8 translocation protein TolB compare
BWI76_RS03105 -1.1 -1.1 myo-inosose-2 dehydratase compare
BWI76_RS12450 -1.1 -1.5 phage shock protein PspA compare
BWI76_RS13980 -1.1 -1.3 hypothetical protein compare
BWI76_RS25505 -1.1 -4.5 RNase E specificity factor CsrD compare
BWI76_RS00305 -1.1 -5.6 GntR family transcriptional regulator compare
BWI76_RS03660 -1.1 -2.7 hypothetical protein compare
BWI76_RS02765 -1.1 -4.7 membrane protein compare
BWI76_RS20720 -1.1 -1.1 hypothetical protein compare
BWI76_RS15000 -1.1 -3.0 amino acid ABC transporter ATP-binding protein compare
BWI76_RS15830 -1.1 -2.0 hypothetical protein compare
BWI76_RS01090 -1.1 -3.2 UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing) compare
BWI76_RS00440 -1.1 -1.4 CopG family transcriptional regulator compare
BWI76_RS21980 -1.1 -1.7 hypothetical protein compare
BWI76_RS02180 -1.0 -1.3 hypothetical protein compare
BWI76_RS18905 -1.0 -2.6 putrescine/spermidine ABC transporter compare
BWI76_RS08585 -1.0 -1.1 nicotinamide riboside transporter PnuC compare
BWI76_RS26130 -1.0 -3.6 ADP compounds hydrolase NudE compare
BWI76_RS09655 -1.0 -2.5 leucine-responsive regulatory protein compare
BWI76_RS09030 -1.0 -4.0 transpeptidase compare
BWI76_RS27460 -1.0 -4.1 hypothetical protein compare
BWI76_RS27915 -1.0 -1.6 YceK/YidQ family lipoprotein compare
BWI76_RS09755 -1.0 -3.5 phosphoserine transaminase compare
BWI76_RS11700 -1.0 -1.1 hypothetical protein compare
BWI76_RS25065 -1.0 -1.9 polyribonucleotide nucleotidyltransferase compare
BWI76_RS22120 -1.0 -3.4 glutamate--cysteine ligase compare
BWI76_RS16120 -1.0 -1.6 4-carboxymuconolactone decarboxylase compare
BWI76_RS07605 -1.0 -2.4 N-acetyltransferase GCN5 compare
BWI76_RS08215 -1.0 -2.8 glucosamine-6-phosphate deaminase compare
BWI76_RS17190 -1.0 -2.7 TonB system transport protein TonB compare
BWI76_RS26645 -1.0 -5.9 ferrous iron transporter B compare
BWI76_RS15435 -1.0 -1.2 hypothetical protein compare
BWI76_RS00885 -0.9 -2.9 tRNA (uridine(54)-C5)-methyltransferase TrmA compare
BWI76_RS16955 -0.9 -1.0 hypothetical protein compare
BWI76_RS04090 -0.9 -2.2 ribosomal-protein-alanine N-acetyltransferase RimI compare
BWI76_RS15360 -0.9 -2.4 hypothetical protein compare
BWI76_RS15850 -0.9 -1.1 DUF1317 domain-containing protein compare
BWI76_RS05175 -0.9 -7.4 dGTPase compare
BWI76_RS12855 -0.9 -1.7 enamine deaminase RidA compare
BWI76_RS00415 -0.9 -2.5 glucose-1-phosphatase compare
BWI76_RS02530 -0.9 -1.0 tRNA dimethylallyltransferase compare
BWI76_RS04240 -0.9 -1.7 thr operon leader peptide compare
BWI76_RS06800 -0.9 -1.1 DUF2496 domain-containing protein compare
BWI76_RS01105 -0.9 -1.7 glucose-1-phosphate thymidylyltransferase compare
BWI76_RS02325 -0.9 -4.6 anaerobic C4-dicarboxylate transporter compare
BWI76_RS26440 -0.9 -1.1 hypothetical protein compare
BWI76_RS19330 -0.9 -0.9 HAD family hydrolase compare
BWI76_RS12790 -0.9 -0.8 lactate dehydrogenase compare
BWI76_RS08430 -0.9 -3.3 succinate--CoA ligase subunit alpha compare
BWI76_RS11820 -0.9 -0.9 short-chain dehydrogenase/reductase SDR compare


Specific Phenotypes

For 29 genes in this experiment

For stress Nickel (II) chloride hexahydrate in Klebsiella michiganensis M5al

For stress Nickel (II) chloride hexahydrate across organisms