Experiment set7IT040 for Pseudomonas fluorescens FW300-N2E2

Compare to:

LB with Zinc chloride 0.0000015625 M

200 most important genes:

  gene name fitness t score description  
Pf6N2E2_2129 -6.6 -3.8 Predicted dye-decolorizing peroxidase (DyP), YfeX-like subgroup compare
Pf6N2E2_4353 -6.1 -5.5 Hydrogen peroxide-inducible genes activator compare
Pf6N2E2_5069 -5.3 -5.1 putative Cytochrome bd2, subunit II compare
Pf6N2E2_5609 -5.2 -5.1 DNA-binding response regulator ColR compare
Pf6N2E2_3264 -5.1 -2.6 Uncharacterized protein YrbK clustered with lipopolysaccharide transporters compare
Pf6N2E2_2526 -5.0 -6.8 Similar to phosphoglycolate phosphatase, clustered with ubiquinone biosynthesis SAM-dependent O-methyltransferase compare
Pf6N2E2_3947 -4.9 -2.2 Cd(II)/Pb(II)-responsive transcriptional regulator compare
Pf6N2E2_5027 -4.9 -12.6 AMP nucleosidase (EC 3.2.2.4) compare
Pf6N2E2_5014 -4.8 -1.3 Apolipoprotein N-acyltransferase (EC 2.3.1.-) / Copper homeostasis protein CutE compare
Pf6N2E2_5068 -4.8 -11.6 putative Cytochrome bd2, subunit I compare
Pf6N2E2_4809 -4.7 -16.6 COG3178: Predicted phosphotransferase related to Ser/Thr protein kinases compare
Pf6N2E2_4071 -4.7 -4.4 Phosphate transport system regulatory protein PhoU compare
Pf6N2E2_3948 -4.5 -12.3 Lead, cadmium, zinc and mercury transporting ATPase (EC 3.6.3.3) (EC 3.6.3.5); Copper-translocating P-type ATPase (EC 3.6.3.4) compare
Pf6N2E2_4773 -4.5 -1.2 Coenzyme PQQ synthesis protein D compare
Pf6N2E2_5430 -4.4 -8.4 Transglycosylase, Slt family compare
Pf6N2E2_5841 -4.2 -1.1 GlcG protein compare
Pf6N2E2_5328 -4.2 -4.7 FIG00958649: hypothetical protein compare
Pf6N2E2_2675 -4.0 -1.0 ATP-dependent RNA helicase SrmB compare
Pf6N2E2_4743 -4.0 -1.0 hypothetical protein compare
Pf6N2E2_4352 -4.0 -2.7 ATP-dependent DNA helicase RecG (EC 3.6.1.-) compare
Pf6N2E2_3829 -4.0 -5.3 Protein export cytoplasm chaperone protein (SecB, maintains protein to be exported in unfolded state) compare
Pf6N2E2_2281 -3.9 -2.2 Beta N-acetyl-glucosaminidase (EC 3.2.1.52) compare
Pf6N2E2_3261 -3.9 -3.8 hypothetical protein compare
Pf6N2E2_622 -3.9 -4.3 BatA (Bacteroides aerotolerance operon) compare
Pf6N2E2_724 -3.8 -1.4 Nitric oxide -responding transcriptional regulator Dnr (Crp/Fnr family) compare
Pf6N2E2_2487 -3.7 -1.0 FIG00956090: hypothetical protein compare
Pf6N2E2_3270 -3.7 -2.6 Hypothetical ATP-binding protein UPF0042, contains P-loop compare
Pf6N2E2_2402 -3.7 -2.2 hypothetical protein compare
Pf6N2E2_620 -3.7 -7.8 BatD compare
Pf6N2E2_2971 -3.6 -16.4 AmpG permease compare
Pf6N2E2_2285 -3.6 -1.3 FIG00954079: hypothetical protein compare
Pf6N2E2_625 -3.5 -5.9 MoxR-like ATPase in aerotolerance operon compare
Pf6N2E2_1502 -3.5 -1.7 Two-component system regulatory protein compare
Pf6N2E2_2420 -3.5 -2.5 hypothetical protein compare
Pf6N2E2_1288 -3.5 -2.0 Protein containing transglutaminase-like domain, putative cysteine protease compare
Pf6N2E2_3607 -3.4 -9.1 3'-to-5' exoribonuclease RNase R compare
Pf6N2E2_3665 -3.4 -0.9 serine/threonine protein kinase compare
Pf6N2E2_4810 -3.4 -5.2 Glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) compare
Pf6N2E2_3782 -3.4 -4.3 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) compare
Pf6N2E2_4187 -3.4 -4.0 Lipid A biosynthesis lauroyl acyltransferase (EC 2.3.1.-) compare
Pf6N2E2_4416 -3.3 -3.2 Tyrosine recombinase XerC compare
Pf6N2E2_122 -3.3 -1.6 Tyrosine-protein kinase Wzc (EC 2.7.10.2) compare
Pf6N2E2_4838 -3.3 -9.1 Anhydro-N-acetylmuramic acid kinase (EC 2.7.1.-) compare
Pf6N2E2_3077 -3.3 -3.0 FIG138056: a glutathione-dependent thiol reductase compare
Pf6N2E2_5150 -3.3 -5.8 Glucose-6-phosphate isomerase (EC 5.3.1.9) compare
Pf6N2E2_5733 -3.2 -4.7 NLP/P60 family protein compare
Pf6N2E2_2384 -3.2 -4.8 CmpX compare
Pf6N2E2_4077 -3.2 -1.9 cytosolic long-chain acyl-CoA thioester hydrolase family protein compare
Pf6N2E2_3876 -3.2 -5.4 Agmatine deiminase (EC 3.5.3.12) compare
Pf6N2E2_3612 -3.2 -2.2 HflK protein compare
Pf6N2E2_3179 -3.2 -2.1 FIG021952: putative membrane protein compare
Pf6N2E2_3252 -3.1 -7.8 Histidinol dehydrogenase (EC 1.1.1.23) compare
Pf6N2E2_2927 -3.1 -2.2 Putative signal peptide protein compare
Pf6N2E2_624 -3.1 -5.7 hypothetical protein PA3071 compare
Pf6N2E2_2219 -3.1 -1.8 Cell division trigger factor (EC 5.2.1.8) compare
Pf6N2E2_5406 -3.1 -2.7 FIG00958224: hypothetical protein compare
Pf6N2E2_2181 -3.1 -1.8 Arginine N-succinyltransferase (EC 2.3.1.109) compare
Pf6N2E2_623 -3.1 -1.1 FIG00954674: hypothetical protein compare
Pf6N2E2_1896 -3.1 -2.5 hypothetical protein compare
Pf6N2E2_5723 -3.1 -11.5 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) compare
Pf6N2E2_4204 -3.0 -1.5 rRNA small subunit 7-methylguanosine (m7G) methyltransferase GidB compare
Pf6N2E2_4612 -3.0 -5.3 Glutathione synthetase (EC 6.3.2.3) compare
Pf6N2E2_3344 -3.0 -4.2 N-acetylmuramoyl-L-alanine amidase (EC 3.5.1.28) AmpD compare
Pf6N2E2_3941 -3.0 -3.2 Adenosine (5')-pentaphospho-(5'')-adenosine pyrophosphohydrolase (EC 3.6.1.-) compare
Pf6N2E2_3908 -2.9 -6.3 Glutamate--cysteine ligase (EC 6.3.2.2) compare
Pf6N2E2_3842 -2.9 -3.6 Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) compare
Pf6N2E2_5178 -2.9 -1.9 CDP-diacylglycerol--serine O-phosphatidyltransferase (EC 2.7.8.8) compare
Pf6N2E2_3702 -2.9 -2.4 FIG00953907: hypothetical protein compare
Pf6N2E2_178 -2.9 -1.0 Phenylalanyl-tRNA synthetase beta chain (EC 6.1.1.20) compare
Pf6N2E2_4584 -2.9 -2.4 Cell division transporter, ATP-binding protein FtsE (TC 3.A.5.1.1) compare
Pf6N2E2_5155 -2.8 -3.4 Poly(A) polymerase (EC 2.7.7.19) compare
Pf6N2E2_43 -2.8 -5.9 Histidine permease YuiF compare
Pf6N2E2_5103 -2.8 -1.0 Glutamate 5-kinase (EC 2.7.2.11) / RNA-binding C-terminal domain PUA compare
Pf6N2E2_4691 -2.8 -1.4 hypothetical protein compare
Pf6N2E2_2258 -2.8 -8.5 Transaldolase (EC 2.2.1.2) compare
Pf6N2E2_3487 -2.7 -7.1 Lead, cadmium, zinc and mercury transporting ATPase (EC 3.6.3.3) (EC 3.6.3.5); Copper-translocating P-type ATPase (EC 3.6.3.4) compare
Pf6N2E2_3192 -2.7 -3.7 tRNA:Cm32/Um32 methyltransferase compare
Pf6N2E2_234 -2.7 -3.0 FIG00454312: hypothetical protein compare
Pf6N2E2_2264 -2.7 -4.5 NADPH dependent preQ0 reductase (EC 1.7.1.13) compare
Pf6N2E2_1315 -2.7 -1.3 5-carboxymethyl-2-oxo-hex-3- ene-1,7-dioate decarboxylase (EC 4.1.1.68) compare
Pf6N2E2_2755 -2.7 -1.3 Sigma factor RpoE negative regulatory protein RseA compare
Pf6N2E2_5241 -2.7 -1.7 Aminopeptidase N compare
Pf6N2E2_1352 -2.6 -2.3 Cation transport ATPase compare
Pf6N2E2_3611 -2.6 -1.1 HflC protein compare
Pf6N2E2_621 -2.6 -6.3 TPR domain protein in aerotolerance operon compare
Pf6N2E2_3763 -2.5 -2.0 hypothetical protein compare
Pf6N2E2_55 -2.5 -2.2 Probable hydrolase compare
Pf6N2E2_819 -2.5 -2.8 Response regulator compare
Pf6N2E2_3610 -2.5 -3.8 ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) compare
Pf6N2E2_755 -2.5 -7.8 UPF0141 membrane protein YijP possibly required for phosphoethanolamine modification of lipopolysaccharide compare
Pf6N2E2_1747 -2.5 -2.6 3-oxoacyl-[acyl-carrier protein] reductase (EC 1.1.1.100) compare
Pf6N2E2_5242 -2.5 -2.1 Malate:quinone oxidoreductase (EC 1.1.5.4) compare
Pf6N2E2_5544 -2.4 -7.3 TPR repeat containing exported protein; Putative periplasmic protein contains a protein prenylyltransferase domain compare
Pf6N2E2_586 -2.4 -7.4 Membrane-bound lytic murein transglycosylase D precursor (EC 3.2.1.-) compare
Pf6N2E2_2127 -2.4 -4.7 Transcriptional regulator, GntR family domain / Aspartate aminotransferase (EC 2.6.1.1) compare
Pf6N2E2_2480 -2.4 -1.2 FIG00957636: hypothetical protein compare
Pf6N2E2_3095 -2.4 -0.9 hypothetical protein compare
Pf6N2E2_5943 -2.4 -1.7 hypothetical protein compare
Pf6N2E2_2278 -2.4 -11.1 Transcription-repair coupling factor compare
Pf6N2E2_5785 -2.4 -2.0 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_3373 -2.4 -1.6 Outer membrane lipoprotein SmpA, a component of the essential YaeT outer-membrane protein assembly complex compare
Pf6N2E2_2218 -2.3 -4.1 ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92) compare
Pf6N2E2_4889 -2.3 -4.5 Putative transport protein compare
Pf6N2E2_6059 -2.3 -2.2 FIG008443: hypothetical protein compare
Pf6N2E2_5956 -2.3 -4.3 FIG004453: protein YceG like compare
Pf6N2E2_4918 -2.3 -1.4 Ribonucleotide reductase transcriptional regulator NrdR compare
Pf6N2E2_5499 -2.3 -0.8 hypothetical protein compare
Pf6N2E2_4599 -2.2 -2.6 Integral membrane protein YggT, involved in response to extracytoplasmic stress (osmotic shock) compare
Pf6N2E2_5342 -2.2 -2.4 21 kDa hemolysin precursor compare
Pf6N2E2_5316 -2.2 -1.9 Periplasmic thiol:disulfide oxidoreductase DsbB, required for DsbA reoxidation compare
Pf6N2E2_4153 -2.2 -1.4 Sensory box histidine kinase compare
Pf6N2E2_3384 -2.2 -3.6 Predicted L-lactate dehydrogenase, hypothetical protein subunit YkgG compare
Pf6N2E2_2373 -2.2 -2.0 Type III secretion thermoregulatory protein (LcrF,VirF,transcription regulation of virulence plasmid) compare
Pf6N2E2_5156 -2.2 -2.9 Two-component sensor CbrB: intrcellular carbon:nitrogen balance compare
Pf6N2E2_5632 -2.2 -4.4 Aromatic amino acid transport protein AroP compare
Pf6N2E2_2189 -2.2 -5.5 Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4) compare
Pf6N2E2_3100 -2.2 -2.7 FIG00953063: hypothetical protein compare
Pf6N2E2_754 -2.2 -1.1 Histone acetyltransferase HPA2 and related acetyltransferases compare
Pf6N2E2_4372 -2.1 -4.5 FIG00460773: hypothetical protein compare
Pf6N2E2_4145 -2.1 -2.1 ABC-type transport system involved in resistance to organic solvents, periplasmic component USSDB6C compare
Pf6N2E2_648 -2.1 -1.2 General secretion pathway protein K compare
Pf6N2E2_441 -2.1 -2.0 FIG00958773: hypothetical protein compare
Pf6N2E2_3074 -2.1 -1.3 FIG00960973: hypothetical protein compare
Pf6N2E2_4397 -2.1 -2.0 Xanthine phosphoribosyltransferase (EC 2.4.2.22) compare
Pf6N2E2_4762 -2.1 -1.7 Biotin synthesis protein BioH compare
Pf6N2E2_3062 -2.1 -3.9 Membrane-associated zinc metalloprotease compare
Pf6N2E2_1545 -2.1 -4.1 N-carbamoylputrescine amidase (EC 3.5.1.53) compare
Pf6N2E2_3351 -2.1 -4.2 tRNA pseudouridine synthase B (EC 4.2.1.70) compare
Pf6N2E2_2371 -2.1 -1.5 Type III secretion outermembrane contact sensing protein (YopN,Yop4b,LcrE) compare
Pf6N2E2_5781 -2.1 -6.3 Oxidoreductase, zinc-binding compare
Pf6N2E2_5610 -2.1 -4.1 two-component system sensor protein compare
Pf6N2E2_4072 -2.1 -4.7 Phosphate transport ATP-binding protein PstB (TC 3.A.1.7.1) compare
Pf6N2E2_2247 -2.1 -2.5 Transcriptional regulator, AraC family compare
Pf6N2E2_5172 -2.0 -2.8 FOG: TPR repeat compare
Pf6N2E2_2674 -2.0 -0.9 FIG00953856: hypothetical protein compare
Pf6N2E2_3303 -2.0 -3.1 Sensor histidine kinase PrrB (RegB) (EC 2.7.3.-) compare
Pf6N2E2_2519 -2.0 -0.9 Biosynthetic Aromatic amino acid aminotransferase beta (EC 2.6.1.57) compare
Pf6N2E2_1404 -2.0 -2.0 Nitrous oxide reductase maturation transmembrane protein NosY compare
Pf6N2E2_4499 -2.0 -1.5 protein of unknown function DUF86 compare
Pf6N2E2_482 -2.0 -1.5 Transcriptional regulator BkdR of isoleucine and valine catabolism operon compare
Pf6N2E2_5972 -2.0 -2.0 hypothetical protein compare
Pf6N2E2_3617 -2.0 -3.4 N-acetylmuramoyl-L-alanine amidase (EC 3.5.1.28) compare
Pf6N2E2_6058 -2.0 -3.3 FIG139976: hypothetical protein compare
Pf6N2E2_1797 -2.0 -1.8 Transcriptional regulator compare
Pf6N2E2_3738 -1.9 -2.3 General secretion pathway protein L compare
Pf6N2E2_4148 -1.9 -5.1 Glutamate-aspartate carrier protein compare
Pf6N2E2_919 -1.9 -1.4 FIG00954373: hypothetical protein compare
Pf6N2E2_3460 -1.9 -1.3 Exodeoxyribonuclease V beta chain (EC 3.1.11.5) compare
Pf6N2E2_3830 -1.9 -3.2 Glutaredoxin 3 (Grx3) compare
Pf6N2E2_1972 -1.9 -1.3 FIG004780: hypothetical protein in PFGI-1-like cluster compare
Pf6N2E2_304 -1.9 -2.3 Anthranilate phosphoribosyltransferase like (EC 2.4.2.18) compare
Pf6N2E2_3841 -1.8 -3.7 Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) compare
Pf6N2E2_4641 -1.8 -4.0 cytosolic long-chain acyl-CoA thioester hydrolase family protein compare
Pf6N2E2_1803 -1.8 -3.0 Polysaccharide deacetylase compare
Pf6N2E2_5705 -1.8 -1.7 Sensor protein PhoQ (EC 2.7.13.3) compare
Pf6N2E2_4062 -1.8 -2.1 hypothetical protein compare
Pf6N2E2_1966 -1.8 -2.0 SAM-dependent methyltransferases compare
Pf6N2E2_2549 -1.8 -1.1 hypothetical protein compare
Pf6N2E2_5545 -1.8 -2.6 Queuosine Biosynthesis QueE Radical SAM compare
Pf6N2E2_156 -1.8 -1.4 Carbon storage regulator compare
Pf6N2E2_5605 -1.8 -1.9 FxsA protein compare
Pf6N2E2_737 -1.8 -1.0 Ribonucleotide reductase of class III (anaerobic), activating protein (EC 1.97.1.4) compare
Pf6N2E2_5928 -1.8 -4.8 ABC-type multidrug transport system, permease component compare
Pf6N2E2_4188 -1.7 -1.8 DNA-3-methyladenine glycosylase (EC 3.2.2.20) compare
Pf6N2E2_904 -1.7 -2.5 hypothetical protein compare
Pf6N2E2_3744 -1.7 -1.6 General secretion pathway protein F compare
Pf6N2E2_5259 -1.7 -4.1 FIG018329: 1-acyl-sn-glycerol-3-phosphate acyltransferase compare
Pf6N2E2_5086 -1.7 -0.8 hypothetical protein compare
Pf6N2E2_4162 -1.7 -2.3 DNA polymerase I (EC 2.7.7.7) compare
Pf6N2E2_3477 -1.7 -1.1 2-Oxobutyrate oxidase, putative compare
Pf6N2E2_529 -1.7 -3.0 FIG00954439: hypothetical protein compare
Pf6N2E2_2201 -1.7 -3.2 Transmembrane regulator protein PrtR compare
Pf6N2E2_2312 -1.7 -1.1 Cytochrome c oxidase subunit CcoQ (EC 1.9.3.1) compare
Pf6N2E2_2139 -1.7 -2.3 Paraquat-inducible protein A compare
Pf6N2E2_5536 -1.7 -1.4 Holliday junction DNA helicase RuvA compare
Pf6N2E2_2317 -1.7 -3.3 Putative analog of CcoH, COG3198 compare
Pf6N2E2_4585 -1.6 -7.8 Cell division protein FtsX compare
Pf6N2E2_927 -1.6 -2.1 (AJ250023) putative polyketide synthase compare
Pf6N2E2_6060 -1.6 -2.2 Propionate catabolism operon transcriptional regulator of GntR family [predicted] compare
Pf6N2E2_3008 -1.6 -2.8 FIG00954242: hypothetical protein compare
Pf6N2E2_40 -1.6 -3.1 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
Pf6N2E2_4477 -1.6 -3.1 Z-ring-associated protein ZapA compare
Pf6N2E2_6130 -1.6 -2.0 5S RNA compare
Pf6N2E2_4974 -1.6 -3.5 DedA protein compare
Pf6N2E2_1203 -1.6 -2.6 Isoquinoline 1-oxidoreductase alpha subunit (EC 1.3.99.16) compare
Pf6N2E2_4678 -1.6 -0.6 hypothetical protein compare
Pf6N2E2_2617 -1.6 -3.1 dTDP-4-dehydrorhamnose 3,5-epimerase (EC 5.1.3.13) compare
Pf6N2E2_4369 -1.6 -1.9 Exodeoxyribonuclease III (EC 3.1.11.2) compare
Pf6N2E2_2344 -1.6 -6.3 D-alanyl-D-alanine carboxypeptidase (EC 3.4.16.4) compare
Pf6N2E2_248 -1.6 -4.8 hypothetical protein compare
Pf6N2E2_1044 -1.6 -2.4 hypothetical protein compare
Pf6N2E2_4168 -1.6 -4.3 Zinc ABC transporter, inner membrane permease protein ZnuB compare
Pf6N2E2_6063 -1.6 -5.2 2-methylcitrate dehydratase FeS dependent (EC 4.2.1.79) compare
Pf6N2E2_2324 -1.6 -1.8 Adenine phosphoribosyltransferase (EC 2.4.2.7) compare
Pf6N2E2_1821 -1.6 -1.0 Leucine-responsive regulatory protein, regulator for leucine (or lrp) regulon and high-affinity branched-chain amino acid transport system compare
Pf6N2E2_2572 -1.6 -1.6 Chemotaxis regulator - transmits chemoreceptor signals to flagelllar motor components CheY compare
Pf6N2E2_6036 -1.6 -2.8 hypothetical protein compare
Pf6N2E2_5927 -1.6 -2.8 ABC-type multidrug transport system, ATPase component compare
Pf6N2E2_6035 -1.5 -1.0 alpha/beta hydrolase fold compare
Pf6N2E2_2397 -1.5 -2.0 Two-component system response regulator QseB compare


Specific Phenotypes

For 6 genes in this experiment

For stress Zinc chloride in Pseudomonas fluorescens FW300-N2E2

For stress Zinc chloride across organisms