Experiment set7IT039 for Methanococcus maripaludis S2

Compare to:

control, 1x iron with casamino acids and vitamins, formate media

200 most important genes:

  gene name fitness t score description  
MMP_RS01175 -4.3 -7.5 triphosphoribosyl-dephospho-CoA synthase compare
MMP_RS01020 -3.9 -2.5 3 4-dihydroxy-2-butanone-4-phosphate synthase compare
MMP_RS06350 -3.9 -17.3 HesA/MoeB/ThiF family protein compare
MMP_RS06355 -3.9 -7.1 molybdenum cofactor biosynthesis protein MoaE compare
MMP_RS06680 -3.8 -18.9 Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain compare
MMP_RS03015 -3.8 -16.1 GTP 3' 8-cyclase MoaA compare
MMP_RS05515 -3.7 -15.4 cyclic pyranopterin monophosphate synthase MoaC compare
MMP_RS06700 -3.7 -22.6 hypothetical protein compare
MMP_RS06685 -3.7 -16.8 formate dehydrogenase H subunit alpha selenocysteine-containing compare
MMP_RS03315 -3.5 -3.6 ferrous iron transport protein A compare
MMP_RS06345 -3.4 -18.7 formate dehydrogenase accessory sulfurtransferase FdhD compare
MMP_RS07005 -3.4 -1.5 4Fe-4S binding protein compare
MMP_RS07635 -3.3 -11.3 MogA/MoaB family molybdenum cofactor biosynthesis protein compare
MMP_RS02010 -3.1 -13.3 PHP domain-containing protein compare
MMP_RS01005 -3.1 -3.3 riboflavin synthase compare
MMP_RS08820 -3.0 -8.4 hypothetical protein compare
MMP_RS02900 -3.0 -1.3 imidazoleglycerol-phosphate dehydratase HisB compare
MMP_RS00040 -3.0 -7.6 TIGR03576 family pyridoxal phosphate-dependent enzyme compare
MMP_RS06715 -2.9 -20.0 cache domain-containing protein compare
MMP_RS03600 -2.8 -4.9 triose-phosphate isomerase compare
MMP_RS07380 -2.8 -4.4 transcription elongation factor Spt5 compare
MMP_RS01500 -2.8 -5.8 CBS domain-containing protein compare
MMP_RS06720 -2.8 -10.7 response regulator transcription factor compare
MMP_RS08715 -2.7 -3.5 formylmethanofuran dehydrogenase subunit B compare
MMP_RS07445 -2.7 -7.3 helix-turn-helix domain-containing protein compare
MMP_RS08635 -2.6 -4.7 UbiA family prenyltransferase compare
MMP_RS01545 -2.6 -2.4 CBS domain-containing protein compare
MMP_RS07525 -2.5 -10.8 4Fe-4S binding protein compare
MMP_RS04585 -2.5 -11.7 AIR synthase related protein compare
MMP_RS04710 -2.5 -3.6 hypothetical protein compare
MMP_RS00895 -2.5 -6.3 hypothetical protein compare
MMP_RS00115 -2.5 -15.2 radical SAM protein compare
MMP_RS01755 -2.4 -3.4 DUF2097 domain-containing protein compare
MMP_RS06895 -2.4 -4.3 selenocysteine-specific translation elongation factor compare
MMP_RS01610 -2.4 -5.1 hypothetical protein compare
MMP_RS04900 -2.4 -20.6 hypothetical protein compare
MMP_RS06705 -2.4 -9.2 formate/nitrite transporter family protein compare
MMP_RS08645 -2.3 -9.9 UPF0179 family protein compare
MMP_RS03435 -2.3 -3.3 ketol-acid reductoisomerase compare
MMP_RS08745 -2.2 -8.8 CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase compare
MMP_RS02280 -2.2 -1.9 DUF211 domain-containing protein compare
MMP_RS01985 -2.1 -10.8 F420-dependent methylenetetrahydromethanopterin dehydrogenase compare
MMP_RS02240 -2.1 -5.8 methanogenesis marker 7 protein compare
MMP_RS01980 -2.1 -14.1 trimeric intracellular cation channel family protein compare
MMP_RS06105 -2.1 -9.3 hydrogenase maturation peptidase HycI compare
MMP_RS06295 -2.0 -8.9 methanogenesis marker 14 protein compare
MMP_RS06730 -2.0 -3.6 phosphopantothenate/pantothenate synthetase compare
MMP_RS02195 -2.0 -5.3 tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase compare
MMP_RS03960 -2.0 -2.1 hypothetical protein compare
MMP_RS01265 -2.0 -3.1 hypothetical protein compare
MMP_RS04605 -2.0 -8.8 cobalt ECF transporter T component CbiQ compare
MMP_RS05540 -2.0 -3.4 hypothetical protein compare
MMP_RS08460 -2.0 -3.8 proteasome-activating nucleotidase compare
MMP_RS06975 -2.0 -3.8 sulfide-dependent adenosine diphosphate thiazole synthase compare
MMP_RS08720 -2.0 -3.2 4Fe-4S binding protein compare
MMP_RS01800 -2.0 -7.0 TIGR00303 family protein compare
MMP_RS05430 -1.9 -5.1 TIGR00288 family NYN domain-containing protein compare
MMP_RS08300 -1.9 -2.0 metal-sulfur cluster assembly factor compare
MMP_RS07630 -1.9 -3.0 ATP-binding cassette domain-containing protein compare
MMP_RS02355 -1.9 -4.7 30S ribosomal protein S27ae compare
MMP_RS03025 -1.9 -6.3 molybdenum cofactor guanylyltransferase compare
MMP_RS04780 -1.9 -3.9 ribonuclease P compare
MMP_RS06475 -1.9 -8.2 FAD-dependent oxidoreductase compare
MMP_RS01380 -1.9 -6.4 PHP domain-containing protein compare
MMP_RS02345 -1.9 -6.3 GTP-dependent dephospho-CoA kinase family protein compare
MMP_RS04500 -1.8 -12.7 adenosylmethionine--8-amino-7-oxononanoate transaminase compare
MMP_RS07845 -1.8 -3.1 LL-diaminopimelate aminotransferase compare
MMP_RS00305 -1.8 -2.8 phosphoribosyl-ATP diphosphatase compare
MMP_RS06120 -1.8 -3.7 UPF0147 family protein compare
MMP_RS06230 -1.8 -3.6 helix-turn-helix domain-containing protein compare
MMP_RS08790 -1.8 -3.4 translation initiation factor IF-2 subunit alpha compare
MMP_RS03640 -1.8 -5.0 archaeal proteasome endopeptidase complex subunit beta compare
MMP_RS04685 -1.8 -5.2 DUF126 domain-containing protein compare
MMP_RS06175 -1.7 -8.3 winged helix-turn-helix transcriptional regulator compare
MMP_RS01220 -1.7 -11.0 hypothetical protein compare
MMP_RS02800 -1.7 -8.9 nucleotidyltransferase domain-containing protein compare
MMP_RS07545 -1.7 -2.2 HTH domain-containing protein compare
MMP_RS04615 -1.7 -7.0 PDGLE domain-containing protein compare
MMP_RS04620 -1.7 -11.1 cobalt transporter CbiM compare
MMP_RS02165 -1.7 -6.8 tRNA-dihydrouridine synthase compare
MMP_RS05765 -1.7 -7.2 M42 family metallopeptidase compare
MMP_RS05845 -1.7 -3.4 tRNA-intron lyase compare
MMP_RS06370 -1.7 -6.4 biotin synthase BioB compare
MMP_RS08100 -1.6 -8.7 8-amino-7-oxononanoate synthase compare
MMP_RS04870 -1.6 -6.7 TIGR02253 family HAD-type hydrolase compare
MMP_RS08435 -1.6 -3.9 Era-like GTP-binding protein compare
MMP_RS06285 -1.6 -3.7 precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT compare
MMP_RS07765 -1.6 -8.2 sodium:alanine symporter family protein compare
MMP_RS01960 -1.6 -2.0 hypothetical protein compare
MMP_RS08095 -1.6 -9.0 dethiobiotin synthase compare
MMP_RS04775 -1.6 -4.4 adenosylhomocysteinase compare
MMP_RS06020 -1.6 -4.1 archaeoflavoprotein AfpA compare
MMP_RS07685 -1.6 -7.3 TIGR01212 family radical SAM protein compare
MMP_RS00620 -1.6 -7.8 4Fe-4S binding protein compare
MMP_RS06625 -1.5 -3.8 DNA primase compare
MMP_RS07365 -1.5 -11.4 2-phosphoglycerate kinase compare
MMP_RS03580 -1.5 -4.3 signal recognition particle-docking protein FtsY compare
MMP_RS07575 -1.5 -5.7 RNA ligase partner protein compare
MMP_RS08105 -1.5 -8.5 6-carboxyhexanoate--CoA ligase compare
MMP_RS00685 -1.5 -5.4 2-phospho-L-lactate guanylyltransferase compare
MMP_RS03205 -1.5 -1.9 peptidyl-tRNA hydrolase Pth2 compare
MMP_RS08210 -1.5 -2.6 phosphatidylglycerophosphatase A compare
MMP_RS05510 -1.5 -4.7 Rrf2 family transcriptional regulator compare
MMP_RS05245 -1.5 -8.3 archaeosine biosynthesis radical SAM protein RaSEA compare
MMP_RS03035 -1.4 -3.8 4-hydroxy-tetrahydrodipicolinate synthase compare
MMP_RS01365 -1.4 -5.1 archaeal proteasome endopeptidase complex subunit alpha compare
MMP_RS07645 -1.4 -8.2 aldehyde dehydrogenase family protein compare
MMP_RS07605 -1.4 -5.4 diadenylate cyclase compare
MMP_RS00110 -1.4 -3.9 hypothetical protein compare
MMP_RS06400 -1.4 -1.7 4Fe-4S binding protein compare
MMP_RS01250 -1.4 -6.1 tRNA (guanine(26)-N(2))-dimethyltransferase compare
MMP_RS01840 -1.3 -6.4 TIGR00289 family protein compare
MMP_RS06200 -1.3 -7.8 M24 family metallopeptidase compare
MMP_RS03400 -1.3 -3.6 archease compare
MMP_RS06270 -1.3 -5.5 TIGR00300 family protein compare
MMP_RS09020 -1.3 -2.3 hypothetical protein compare
MMP_RS00300 -1.3 -1.0 6 7-dimethyl-8-ribityllumazine synthase compare
MMP_RS02235 -1.3 -7.8 CBS domain-containing protein compare
MMP_RS07730 -1.3 -2.0 pyruvate synthase subunit beta compare
MMP_RS07385 -1.3 -2.8 protein translocase SEC61 complex subunit gamma compare
MMP_RS06840 -1.3 -1.5 DNA-directed RNA polymerase subunit N compare
MMP_RS00915 -1.2 -6.0 DUF116 domain-containing protein compare
MMP_RS06930 -1.2 -8.3 MBL fold metallo-hydrolase compare
MMP_RS07200 -1.2 -5.2 [5-(aminomethyl)furan-3-yl]methyl phosphate kinase compare
MMP_RS08200 -1.2 -10.0 archaeosine synthase subunit alpha compare
MMP_RS07710 -1.2 -6.8 cell division protein FtsZ compare
MMP_RS07600 -1.2 -2.9 Ni-sirohydrochlorin a c-diamide synthase compare
MMP_RS04890 -1.2 -1.1 adenylyltransferase/cytidyltransferase family protein compare
MMP_RS01225 -1.2 -5.5 DUF5379 domain-containing protein compare
MMP_RS06885 -1.1 -2.7 50S ribosome-binding GTPase compare
MMP_RS05875 -1.1 -3.6 hydroxyethylthiazole kinase compare
MMP_RS02190 -1.1 -4.1 sulfopyruvate decarboxylase subunit alpha compare
MMP_RS01195 -1.1 -1.8 metalloregulator ArsR/SmtB family transcription factor compare
MMP_RS06855 -1.1 -8.8 hypothetical protein compare
MMP_RS07735 -1.1 -1.1 2-ketoisovalerate ferredoxin oxidoreductase subunit alpha compare
MMP_RS03475 -1.1 -1.1 hypothetical protein compare
MMP_RS00810 -1.1 -7.6 topoisomerase DNA-binding C4 zinc finger domain-containing protein compare
MMP_RS08690 -1.1 -6.4 RNA-guided pseudouridylation complex pseudouridine synthase subunit Cbf5 compare
MMP_RS06865 -1.1 -1.2 HypC/HybG/HupF family hydrogenase formation chaperone compare
MMP_RS08725 -1.1 -1.4 Ni/Fe hydrogenase subunit alpha compare
MMP_RS01085 -1.1 -2.7 hypothetical protein compare
MMP_RS06670 -1.1 -5.8 glucose-6-phosphate isomerase compare
MMP_RS07435 -1.1 -2.7 GMP synthase subunit A compare
MMP_RS06630 -1.0 -1.2 UPF0058 family protein compare
MMP_RS08615 -1.0 -2.9 flagellar protein G compare
MMP_RS05550 -1.0 -1.0 cation:proton antiporter compare
MMP_RS07775 -1.0 -4.7 alanine dehydrogenase compare
MMP_RS01725 -1.0 -3.5 class I SAM-dependent methyltransferase family protein compare
MMP_RS07425 -1.0 -4.3 GTP-binding protein compare
MMP_RS03095 -1.0 -4.2 diphthine synthase compare
MMP_RS01890 -1.0 -4.0 nucleotide sugar dehydrogenase compare
MMP_RS05555 -1.0 -2.0 DUF4040 domain-containing protein compare
MMP_RS03485 -1.0 -4.8 TIGR00267 family protein compare
MMP_RS05815 -1.0 -1.1 NOL1/NOP2/sun family putative RNA methylase compare
MMP_RS05545 -1.0 -5.2 pyridoxal phosphate-dependent aminotransferase compare
MMP_RS08940 -1.0 -1.7 MetS family NSS transporter small subunit compare
MMP_RS07750 -1.0 -4.9 DUF357 domain-containing protein compare
MMP_RS08650 -1.0 -3.2 glutamine--fructose-6-phosphate transaminase (isomerizing) compare
MMP_RS01180 -1.0 -1.1 XTP/dITP diphosphatase compare
MMP_RS01720 -0.9 -1.5 replication factor C large subunit compare
MMP_RS02340 -0.9 -2.5 DNA-directed RNA polymerase subunit E'' compare
MMP_RS00050 -0.9 -4.4 AarF/UbiB family protein compare
MMP_RS07755 -0.9 -1.7 DUF555 domain-containing protein compare
MMP_RS02245 -0.9 -3.1 hypothetical protein compare
MMP_RS03700 -0.9 -4.7 sodium:proton antiporter compare
MMP_RS08165 -0.9 -3.2 phosphoglycerate dehydrogenase compare
MMP_RS04485 -0.9 -6.4 putative beta-lysine N-acetyltransferase compare
MMP_RS00695 -0.9 -1.2 biotin--[acetyl-CoA-carboxylase] ligase compare
MMP_RS02145 -0.8 -4.8 winged helix-turn-helix transcriptional regulator compare
MMP_RS07390 -0.8 -2.2 cell division protein FtsZ compare
MMP_RS03210 -0.8 -6.8 tRNA guanosine(15) transglycosylase TgtA compare
MMP_RS01700 -0.8 -0.9 dihydroxy-acid dehydratase compare
MMP_RS03555 -0.8 -5.0 transcriptional regulator compare
MMP_RS07345 -0.8 -4.1 glycine synthesis protein GlyXL (from data) compare
MMP_RS01830 -0.8 -1.1 tRNA-Val compare
MMP_RS00130 -0.8 -1.4 nickel-responsive transcriptional regulator NikR compare
MMP_RS00555 -0.8 -3.2 MFS transporter compare
MMP_RS07075 -0.8 -4.4 phosphomannomutase/phosphoglucomutase compare
MMP_RS01045 -0.8 -4.6 diphthamide biosynthesis enzyme Dph2 compare
MMP_RS00985 -0.8 -2.9 CDC48 family AAA ATPase compare
MMP_RS03250 -0.8 -3.5 MJ1244 family protein compare
MMP_RS03120 -0.8 -3.2 hypothetical protein compare
MMP_RS06980 -0.7 -5.4 tRNA 2-thiocytidine biosynthesis TtcA family protein compare
MMP_RS01385 -0.7 -0.7 imidazole glycerol phosphate synthase subunit HisH compare
MMP_RS03440 -0.7 -1.3 MoaD/ThiS family protein compare
MMP_RS07195 -0.7 -3.5 M20 family metallo-hydrolase compare
MMP_RS05440 -0.7 -5.1 winged helix-turn-helix transcriptional regulator compare
MMP_RS07535 -0.7 -3.8 4Fe-4S binding protein compare
MMP_RS06340 -0.7 -4.0 phosphoadenosine phosphosulfate reductase family protein compare
MMP_RS04695 -0.7 -4.4 selenide water dikinase SelD compare
MMP_RS00295 -0.7 -1.9 gamma carbonic anhydrase family protein compare
MMP_RS02605 -0.7 -1.0 MotA/TolQ/ExbB proton channel family protein compare
MMP_RS05285 -0.7 -3.1 MMPL family transporter compare
MMP_RS05280 -0.7 -3.9 COG1361 S-layer family protein compare
MMP_RS06725 -0.7 -4.9 hypothetical protein compare
MMP_RS03110 -0.7 -2.9 glycosyltransferase family 2 protein compare
MMP_RS03680 -0.7 -3.3 hypothetical protein compare
MMP_RS03590 -0.7 -2.9 METTL5 family protein compare
MMP_RS02930 -0.7 -2.6 class I SAM-dependent methyltransferase compare
MMP_RS04955 -0.6 -2.1 DNA topoisomerase I compare


Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in iron experiments

For iron Iron (II) chloride tetrahydrate across organisms