Experiment set7IT038 for Methanococcus maripaludis S2

Compare to:

control, 1x iron with casamino acids and vitamins, formate media

200 most important genes:

  gene name fitness t score description  
MMP_RS06355 -5.1 -4.9 molybdenum cofactor biosynthesis protein MoaE compare
MMP_RS01020 -4.9 -1.9 3 4-dihydroxy-2-butanone-4-phosphate synthase compare
MMP_RS01175 -4.8 -6.6 triphosphoribosyl-dephospho-CoA synthase compare
MMP_RS06680 -4.7 -18.1 Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain compare
MMP_RS06350 -4.6 -13.2 HesA/MoeB/ThiF family protein compare
MMP_RS08300 -4.6 -2.1 metal-sulfur cluster assembly factor compare
MMP_RS06685 -4.4 -18.5 formate dehydrogenase H subunit alpha selenocysteine-containing compare
MMP_RS06700 -4.4 -25.3 hypothetical protein compare
MMP_RS05515 -4.3 -12.1 cyclic pyranopterin monophosphate synthase MoaC compare
MMP_RS03315 -4.2 -2.5 ferrous iron transport protein A compare
MMP_RS03015 -4.2 -15.8 GTP 3' 8-cyclase MoaA compare
MMP_RS07635 -4.0 -14.0 MogA/MoaB family molybdenum cofactor biosynthesis protein compare
MMP_RS06345 -3.8 -13.0 formate dehydrogenase accessory sulfurtransferase FdhD compare
MMP_RS02195 -3.7 -6.0 tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase compare
MMP_RS01005 -3.7 -2.8 riboflavin synthase compare
MMP_RS08635 -3.6 -4.1 UbiA family prenyltransferase compare
MMP_RS08820 -3.6 -10.5 hypothetical protein compare
MMP_RS08720 -3.6 -4.0 4Fe-4S binding protein compare
MMP_RS07005 -3.3 -1.2 4Fe-4S binding protein compare
MMP_RS04900 -3.2 -21.3 hypothetical protein compare
MMP_RS02010 -3.2 -15.9 PHP domain-containing protein compare
MMP_RS08435 -3.2 -4.1 Era-like GTP-binding protein compare
MMP_RS06295 -3.2 -11.2 methanogenesis marker 14 protein compare
MMP_RS00695 -3.2 -1.6 biotin--[acetyl-CoA-carboxylase] ligase compare
MMP_RS01500 -3.1 -4.3 CBS domain-containing protein compare
MMP_RS06715 -3.1 -19.7 cache domain-containing protein compare
MMP_RS01755 -3.1 -2.4 DUF2097 domain-containing protein compare
MMP_RS04605 -3.1 -8.5 cobalt ECF transporter T component CbiQ compare
MMP_RS07445 -3.0 -6.4 helix-turn-helix domain-containing protein compare
MMP_RS02900 -3.0 -1.1 imidazoleglycerol-phosphate dehydratase HisB compare
MMP_RS00515 -2.9 -1.5 DUF655 domain-containing protein compare
MMP_RS08790 -2.9 -3.6 translation initiation factor IF-2 subunit alpha compare
MMP_RS06720 -2.9 -12.5 response regulator transcription factor compare
MMP_RS02280 -2.8 -1.7 DUF211 domain-containing protein compare
MMP_RS06400 -2.8 -2.8 4Fe-4S binding protein compare
MMP_RS07525 -2.8 -9.1 4Fe-4S binding protein compare
MMP_RS01610 -2.7 -7.1 hypothetical protein compare
MMP_RS06895 -2.7 -2.7 selenocysteine-specific translation elongation factor compare
MMP_RS00040 -2.7 -5.7 TIGR03576 family pyridoxal phosphate-dependent enzyme compare
MMP_RS03600 -2.6 -4.2 triose-phosphate isomerase compare
MMP_RS00115 -2.6 -16.0 radical SAM protein compare
MMP_RS07630 -2.6 -2.9 ATP-binding cassette domain-containing protein compare
MMP_RS08715 -2.6 -2.7 formylmethanofuran dehydrogenase subunit B compare
MMP_RS04585 -2.5 -10.0 AIR synthase related protein compare
MMP_RS01265 -2.5 -3.6 hypothetical protein compare
MMP_RS03400 -2.5 -3.0 archease compare
MMP_RS07755 -2.5 -2.4 DUF555 domain-containing protein compare
MMP_RS04500 -2.5 -17.4 adenosylmethionine--8-amino-7-oxononanoate transaminase compare
MMP_RS06105 -2.4 -8.8 hydrogenase maturation peptidase HycI compare
MMP_RS08095 -2.4 -11.8 dethiobiotin synthase compare
MMP_RS02345 -2.4 -5.1 GTP-dependent dephospho-CoA kinase family protein compare
MMP_RS01220 -2.4 -11.4 hypothetical protein compare
MMP_RS06370 -2.4 -8.1 biotin synthase BioB compare
MMP_RS08745 -2.4 -9.2 CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase compare
MMP_RS07380 -2.3 -4.0 transcription elongation factor Spt5 compare
MMP_RS00895 -2.3 -5.2 hypothetical protein compare
MMP_RS01225 -2.3 -7.9 DUF5379 domain-containing protein compare
MMP_RS01980 -2.2 -13.3 trimeric intracellular cation channel family protein compare
MMP_RS04775 -2.2 -5.9 adenosylhomocysteinase compare
MMP_RS03025 -2.2 -7.4 molybdenum cofactor guanylyltransferase compare
MMP_RS02240 -2.2 -6.5 methanogenesis marker 7 protein compare
MMP_RS06285 -2.2 -4.9 precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT compare
MMP_RS08105 -2.2 -9.3 6-carboxyhexanoate--CoA ligase compare
MMP_RS01545 -2.2 -1.9 CBS domain-containing protein compare
MMP_RS06270 -2.2 -7.7 TIGR00300 family protein compare
MMP_RS07845 -2.2 -3.2 LL-diaminopimelate aminotransferase compare
MMP_RS04620 -2.1 -11.3 cobalt transporter CbiM compare
MMP_RS01380 -2.1 -7.8 PHP domain-containing protein compare
MMP_RS08645 -2.1 -9.3 UPF0179 family protein compare
MMP_RS04870 -2.1 -8.9 TIGR02253 family HAD-type hydrolase compare
MMP_RS08100 -2.1 -7.5 8-amino-7-oxononanoate synthase compare
MMP_RS04615 -2.0 -7.5 PDGLE domain-containing protein compare
MMP_RS07735 -2.0 -1.8 2-ketoisovalerate ferredoxin oxidoreductase subunit alpha compare
MMP_RS06625 -2.0 -3.5 DNA primase compare
MMP_RS01250 -2.0 -6.2 tRNA (guanine(26)-N(2))-dimethyltransferase compare
MMP_RS03640 -2.0 -4.6 archaeal proteasome endopeptidase complex subunit beta compare
MMP_RS01985 -1.9 -7.4 F420-dependent methylenetetrahydromethanopterin dehydrogenase compare
MMP_RS04780 -1.9 -3.9 ribonuclease P compare
MMP_RS06705 -1.9 -6.8 formate/nitrite transporter family protein compare
MMP_RS00300 -1.9 -1.1 6 7-dimethyl-8-ribityllumazine synthase compare
MMP_RS05540 -1.8 -3.3 hypothetical protein compare
MMP_RS05765 -1.8 -6.8 M42 family metallopeptidase compare
MMP_RS06730 -1.8 -2.0 phosphopantothenate/pantothenate synthetase compare
MMP_RS07600 -1.8 -3.7 Ni-sirohydrochlorin a c-diamide synthase compare
MMP_RS06120 -1.8 -2.6 UPF0147 family protein compare
MMP_RS02235 -1.8 -9.4 CBS domain-containing protein compare
MMP_RS00685 -1.8 -4.5 2-phospho-L-lactate guanylyltransferase compare
MMP_RS05245 -1.8 -9.3 archaeosine biosynthesis radical SAM protein RaSEA compare
MMP_RS06020 -1.8 -5.9 archaeoflavoprotein AfpA compare
MMP_RS08460 -1.8 -3.7 proteasome-activating nucleotidase compare
MMP_RS07575 -1.8 -6.6 RNA ligase partner protein compare
MMP_RS03580 -1.8 -3.8 signal recognition particle-docking protein FtsY compare
MMP_RS02190 -1.8 -5.6 sulfopyruvate decarboxylase subunit alpha compare
MMP_RS07685 -1.8 -7.9 TIGR01212 family radical SAM protein compare
MMP_RS07645 -1.8 -9.1 aldehyde dehydrogenase family protein compare
MMP_RS00305 -1.7 -2.7 phosphoribosyl-ATP diphosphatase compare
MMP_RS09020 -1.7 -2.4 hypothetical protein compare
MMP_RS00620 -1.7 -8.5 4Fe-4S binding protein compare
MMP_RS05875 -1.7 -6.3 hydroxyethylthiazole kinase compare
MMP_RS03035 -1.7 -3.5 4-hydroxy-tetrahydrodipicolinate synthase compare
MMP_RS06475 -1.7 -4.5 FAD-dependent oxidoreductase compare
MMP_RS07605 -1.6 -5.8 diadenylate cyclase compare
MMP_RS07765 -1.6 -6.8 sodium:alanine symporter family protein compare
MMP_RS02800 -1.6 -7.9 nucleotidyltransferase domain-containing protein compare
MMP_RS07365 -1.6 -11.1 2-phosphoglycerate kinase compare
MMP_RS04890 -1.6 -1.2 adenylyltransferase/cytidyltransferase family protein compare
MMP_RS02355 -1.6 -4.7 30S ribosomal protein S27ae compare
MMP_RS05250 -1.6 -2.6 NFYB/HAP3 family transcription factor subunit compare
MMP_RS05555 -1.6 -2.5 DUF4040 domain-containing protein compare
MMP_RS04685 -1.6 -3.1 DUF126 domain-containing protein compare
MMP_RS02165 -1.6 -7.3 tRNA-dihydrouridine synthase compare
MMP_RS06885 -1.6 -2.5 50S ribosome-binding GTPase compare
MMP_RS03445 -1.5 -1.4 methanogenesis marker 17 protein compare
MMP_RS05430 -1.5 -5.0 TIGR00288 family NYN domain-containing protein compare
MMP_RS05265 -1.5 -3.2 2-isopropylmalate synthase compare
MMP_RS03205 -1.5 -2.5 peptidyl-tRNA hydrolase Pth2 compare
MMP_RS06200 -1.5 -9.0 M24 family metallopeptidase compare
MMP_RS06930 -1.5 -7.6 MBL fold metallo-hydrolase compare
MMP_RS06175 -1.5 -7.2 winged helix-turn-helix transcriptional regulator compare
MMP_RS02340 -1.4 -2.5 DNA-directed RNA polymerase subunit E'' compare
MMP_RS07580 -1.4 -3.0 DUF356 domain-containing protein compare
MMP_RS06925 -1.4 -3.3 ribonuclease VapC4 compare
MMP_RS01365 -1.4 -3.6 archaeal proteasome endopeptidase complex subunit alpha compare
MMP_RS07195 -1.4 -7.1 M20 family metallo-hydrolase compare
MMP_RS01800 -1.4 -4.1 TIGR00303 family protein compare
MMP_RS01700 -1.4 -1.0 dihydroxy-acid dehydratase compare
MMP_RS02135 -1.4 -3.7 DUF5612 domain-containing protein compare
MMP_RS08785 -1.4 -1.3 RNA-protein complex protein Nop10 compare
MMP_RS08210 -1.4 -2.9 phosphatidylglycerophosphatase A compare
MMP_RS03095 -1.3 -5.1 diphthine synthase compare
MMP_RS01840 -1.3 -8.5 TIGR00289 family protein compare
MMP_RS05545 -1.3 -5.7 pyridoxal phosphate-dependent aminotransferase compare
MMP_RS07390 -1.3 -2.2 cell division protein FtsZ compare
MMP_RS06855 -1.3 -9.1 hypothetical protein compare
MMP_RS05510 -1.3 -4.3 Rrf2 family transcriptional regulator compare
MMP_RS01795 -1.3 -2.4 methanogenesis marker 6 protein compare
MMP_RS05815 -1.3 -1.4 NOL1/NOP2/sun family putative RNA methylase compare
MMP_RS01335 -1.3 -2.3 prefoldin subunit beta compare
MMP_RS01385 -1.3 -0.9 imidazole glycerol phosphate synthase subunit HisH compare
MMP_RS01720 -1.3 -1.4 replication factor C large subunit compare
MMP_RS00320 -1.3 -2.1 class I SAM-dependent methyltransferase compare
MMP_RS07200 -1.2 -5.7 [5-(aminomethyl)furan-3-yl]methyl phosphate kinase compare
MMP_RS02875 -1.2 -7.0 chorismate pyruvate-lyase family protein compare
MMP_RS07385 -1.2 -1.8 protein translocase SEC61 complex subunit gamma compare
MMP_RS02145 -1.2 -5.1 winged helix-turn-helix transcriptional regulator compare
MMP_RS08200 -1.2 -9.6 archaeosine synthase subunit alpha compare
MMP_RS06230 -1.2 -2.2 helix-turn-helix domain-containing protein compare
MMP_RS05930 -1.2 -3.1 3-isopropylmalate dehydratase large subunit compare
MMP_RS01725 -1.2 -3.0 class I SAM-dependent methyltransferase family protein compare
MMP_RS08690 -1.2 -7.2 RNA-guided pseudouridylation complex pseudouridine synthase subunit Cbf5 compare
MMP_RS06340 -1.2 -5.8 phosphoadenosine phosphosulfate reductase family protein compare
MMP_RS00810 -1.1 -5.4 topoisomerase DNA-binding C4 zinc finger domain-containing protein compare
MMP_RS06630 -1.1 -1.0 UPF0058 family protein compare
MMP_RS00130 -1.1 -1.6 nickel-responsive transcriptional regulator NikR compare
MMP_RS08940 -1.1 -1.7 MetS family NSS transporter small subunit compare
MMP_RS07425 -1.1 -6.7 GTP-binding protein compare
MMP_RS03485 -1.1 -3.6 TIGR00267 family protein compare
MMP_RS01960 -1.1 -0.8 hypothetical protein compare
MMP_RS00110 -1.1 -3.3 hypothetical protein compare
MMP_RS05345 -1.1 -4.8 hypothetical protein compare
MMP_RS08615 -1.1 -1.8 flagellar protein G compare
MMP_RS08650 -1.1 -3.0 glutamine--fructose-6-phosphate transaminase (isomerizing) compare
MMP_RS00295 -1.1 -1.4 gamma carbonic anhydrase family protein compare
MMP_RS01325 -1.0 -1.9 dihydroneopterin aldolase family protein compare
MMP_RS08165 -1.0 -1.6 phosphoglycerate dehydrogenase compare
MMP_RS07535 -1.0 -5.2 4Fe-4S binding protein compare
MMP_RS04090 -1.0 -2.3 hypothetical protein compare
MMP_RS03700 -1.0 -5.3 sodium:proton antiporter compare
MMP_RS07710 -1.0 -4.5 cell division protein FtsZ compare
MMP_RS06865 -1.0 -1.4 HypC/HybG/HupF family hydrogenase formation chaperone compare
MMP_RS00915 -1.0 -4.1 DUF116 domain-containing protein compare
MMP_RS07750 -1.0 -3.3 DUF357 domain-containing protein compare
MMP_RS00050 -1.0 -5.3 AarF/UbiB family protein compare
MMP_RS06975 -1.0 -2.2 sulfide-dependent adenosine diphosphate thiazole synthase compare
MMP_RS01085 -1.0 -2.1 hypothetical protein compare
MMP_RS03590 -1.0 -3.1 METTL5 family protein compare
MMP_RS04695 -1.0 -4.0 selenide water dikinase SelD compare
MMP_RS03250 -0.9 -3.7 MJ1244 family protein compare
MMP_RS00555 -0.9 -3.6 MFS transporter compare
MMP_RS06215 -0.9 -2.5 30S ribosomal protein S6e compare
MMP_RS03210 -0.9 -7.0 tRNA guanosine(15) transglycosylase TgtA compare
MMP_RS03435 -0.9 -1.1 ketol-acid reductoisomerase compare
MMP_RS09055 -0.9 -1.1 CAP domain-containing protein compare
MMP_RS07545 -0.9 -1.2 HTH domain-containing protein compare
MMP_RS01890 -0.9 -3.0 nucleotide sugar dehydrogenase compare
MMP_RS05845 -0.9 -1.7 tRNA-intron lyase compare
MMP_RS02245 -0.9 -2.5 hypothetical protein compare
MMP_RS01830 -0.9 -1.2 tRNA-Val compare
MMP_RS01745 -0.9 -3.6 AMP phosphorylase compare
MMP_RS04710 -0.9 -1.5 hypothetical protein compare
MMP_RS06035 -0.9 -6.0 glycosyltransferase family 2 protein compare
MMP_RS07555 -0.8 -0.6 monovalent cation/H+ antiporter subunit E compare
MMP_RS07730 -0.8 -1.7 pyruvate synthase subunit beta compare
MMP_RS03520 -0.8 -1.4 YwbE family protein compare
MMP_RS01885 -0.8 -4.6 Gfo/Idh/MocA family oxidoreductase compare
MMP_RS06840 -0.8 -0.9 DNA-directed RNA polymerase subunit N compare
MMP_RS02790 -0.8 -1.2 class III signal peptide-containing protein compare
MMP_RS05285 -0.8 -3.2 MMPL family transporter compare
MMP_RS03140 -0.8 -6.1 hypothetical protein compare
MMP_RS07090 -0.8 -4.1 tRNA (adenine-N1)-methyltransferase compare


Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in iron experiments

For iron Iron (II) chloride tetrahydrate across organisms