Experiment set7IT025 for Pseudomonas fluorescens FW300-N2E2

Compare to:

LB with Lomefloxacin hydrochloride 0.0002 mM

200 most important genes:

  gene name fitness t score description  
Pf6N2E2_3840 -5.0 -9.0 FIG00956267: hypothetical protein conserved
Pf6N2E2_4416 -4.8 -3.3 Tyrosine recombinase XerC compare
Pf6N2E2_3842 -4.6 -6.3 Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) compare
Pf6N2E2_3168 -4.5 -9.6 Exodeoxyribonuclease VII large subunit (EC 3.1.11.6) conserved
Pf6N2E2_464 -4.4 -3.6 Sensory histidine kinase QseC compare
Pf6N2E2_3460 -4.2 -2.9 Exodeoxyribonuclease V beta chain (EC 3.1.11.5) compare
Pf6N2E2_4362 -4.0 -5.3 DNA-directed RNA polymerase omega subunit (EC 2.7.7.6) compare
Pf6N2E2_4075 -3.9 -7.9 Phosphate ABC transporter, periplasmic phosphate-binding protein PstS (TC 3.A.1.7.1) compare
Pf6N2E2_2825 -3.7 -3.6 RND efflux system, outer membrane lipoprotein CmeC compare
Pf6N2E2_5219 -3.6 -10.5 FIG140336: TPR domain protein compare
Pf6N2E2_4273 -3.5 -10.3 ATP-dependent DNA helicase UvrD/PcrA compare
Pf6N2E2_5527 -3.4 -2.3 Cold shock protein CspC compare
Pf6N2E2_463 -3.4 -7.2 Transcriptional regulatory protein RstA compare
Pf6N2E2_2217 -3.3 -5.4 ATP-dependent Clp protease ATP-binding subunit ClpX compare
Pf6N2E2_3841 -3.2 -6.5 Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) compare
Pf6N2E2_4352 -3.2 -5.2 ATP-dependent DNA helicase RecG (EC 3.6.1.-) compare
Pf6N2E2_5845 -3.1 -8.3 Nucleoside ABC transporter, periplasmic nucleoside-binding protein compare
Pf6N2E2_2823 -3.1 -4.8 Multidrug efflux RND membrane fusion protein MexC compare
Pf6N2E2_2992 -3.1 -7.0 Regulatory protein RecX compare
Pf6N2E2_6057 -3.0 -4.2 FIG002781: Alpha-L-glutamate ligase family protein compare
Pf6N2E2_2973 -3.0 -6.8 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
Pf6N2E2_3264 -3.0 -3.1 Uncharacterized protein YrbK clustered with lipopolysaccharide transporters compare
Pf6N2E2_4072 -2.8 -7.1 Phosphate transport ATP-binding protein PstB (TC 3.A.1.7.1) compare
Pf6N2E2_2824 -2.8 -7.2 RND efflux system, inner membrane transporter CmeB compare
Pf6N2E2_6058 -2.8 -7.2 FIG139976: hypothetical protein compare
Pf6N2E2_2699 -2.7 -9.6 Fe(2+)/alpha-ketoglutarate-dependent dioxygenase LpxO conserved
Pf6N2E2_4162 -2.7 -5.0 DNA polymerase I (EC 2.7.7.7) compare
Pf6N2E2_3261 -2.6 -4.9 hypothetical protein compare
Pf6N2E2_3607 -2.5 -9.2 3'-to-5' exoribonuclease RNase R compare
Pf6N2E2_5006 -2.5 -10.6 Muramoyltetrapeptide carboxypeptidase (EC 3.4.17.13) compare
Pf6N2E2_4187 -2.5 -6.0 Lipid A biosynthesis lauroyl acyltransferase (EC 2.3.1.-) compare
Pf6N2E2_3039 -2.5 -9.2 Protein-L-isoaspartate O-methyltransferase (EC 2.1.1.77) compare
Pf6N2E2_5171 -2.4 -15.5 Multimodular transpeptidase-transglycosylase (EC 2.4.1.129) (EC 3.4.-.-) compare
Pf6N2E2_3060 -2.4 -2.2 Outer membrane protein H precursor compare
Pf6N2E2_3370 -2.4 -10.3 DNA repair protein RecN conserved
Pf6N2E2_5076 -2.4 -7.3 DNA repair protein RadA conserved
Pf6N2E2_3257 -2.4 -4.5 Uncharacterized ABC transporter, auxiliary component YrbC compare
Pf6N2E2_288 -2.4 -3.1 Isocitrate dehydrogenase [NADP] (EC 1.1.1.42); Monomeric isocitrate dehydrogenase [NADP] (EC 1.1.1.42) compare
Pf6N2E2_2218 -2.2 -5.4 ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92) compare
Pf6N2E2_4418 -2.2 -1.8 Diaminopimelate epimerase (EC 5.1.1.7) compare
Pf6N2E2_1660 -2.2 -3.8 RND efflux system, membrane fusion protein CmeA compare
Pf6N2E2_5846 -2.2 -10.7 Nucleoside ABC transporter, periplasmic nucleoside-binding protein conserved
Pf6N2E2_1661 -2.2 -7.5 RND efflux system, inner membrane transporter CmeB conserved
Pf6N2E2_3835 -2.1 -3.8 Carboxyl-terminal protease (EC 3.4.21.102) compare
Pf6N2E2_5346 -2.1 -4.3 rRNA small subunit methyltransferase I compare
Pf6N2E2_5103 -2.1 -2.0 Glutamate 5-kinase (EC 2.7.2.11) / RNA-binding C-terminal domain PUA compare
Pf6N2E2_2080 -2.0 -1.9 hypothetical protein compare
Pf6N2E2_5183 -2.0 -12.2 Paraquat-inducible protein B compare
Pf6N2E2_6059 -2.0 -3.6 FIG008443: hypothetical protein compare
Pf6N2E2_3856 -2.0 -7.4 Lysine-arginine-ornithine-binding periplasmic protein precursor (TC 3.A.1.3.1) conserved
Pf6N2E2_5987 -1.9 -6.3 OmpA family protein compare
Pf6N2E2_5181 -1.9 -9.6 Paraquat-inducible protein A compare
Pf6N2E2_1116 -1.9 -2.5 Inosine-5'-monophosphate dehydrogenase (EC 1.1.1.205) compare
Pf6N2E2_5534 -1.9 -4.7 FIG000859: hypothetical protein YebC compare
Pf6N2E2_4453 -1.9 -14.1 Polyphosphate kinase (EC 2.7.4.1) compare
Pf6N2E2_4074 -1.8 -9.0 Phosphate transport system permease protein PstC (TC 3.A.1.7.1) compare
Pf6N2E2_2967 -1.8 -2.5 Cold shock protein CspA compare
Pf6N2E2_2261 -1.7 -5.7 VacJ-like lipoprotein precursor compare
Pf6N2E2_2473 -1.7 -1.4 Major outer membrane lipoprotein I compare
Pf6N2E2_5704 -1.7 -5.7 Transcriptional regulatory protein PhoP compare
Pf6N2E2_3260 -1.7 -5.9 Uncharacterized ABC transporter, ATP-binding protein YrbF compare
Pf6N2E2_3270 -1.7 -4.5 Hypothetical ATP-binding protein UPF0042, contains P-loop compare
Pf6N2E2_5780 -1.7 -8.6 Periplasmic protease compare
Pf6N2E2_2940 -1.7 -6.4 OmpA family protein compare
Pf6N2E2_5727 -1.6 -4.8 FIG00955360: hypothetical protein compare
Pf6N2E2_160 -1.6 -3.2 hypothetical protein compare
Pf6N2E2_3258 -1.6 -5.0 Uncharacterized ABC transporter, periplasmic component YrbD compare
Pf6N2E2_241 -1.5 -1.2 hypothetical protein compare
Pf6N2E2_2942 -1.5 -8.1 ATP-dependent helicase DinG/Rad3 conserved
Pf6N2E2_3612 -1.5 -2.9 HflK protein compare
Pf6N2E2_4218 -1.5 -8.3 hypothetical protein compare
Pf6N2E2_3493 -1.5 -3.8 3-oxoacyl-[acyl-carrier protein] reductase (EC 1.1.1.100) compare
Pf6N2E2_3095 -1.5 -1.5 hypothetical protein compare
Pf6N2E2_3568 -1.5 -3.0 Unsaturated fatty acid biosythesis repressor FabR, TetR family compare
Pf6N2E2_3100 -1.5 -4.0 FIG00953063: hypothetical protein compare
Pf6N2E2_4417 -1.5 -3.1 Protein of unknown function DUF484 compare
Pf6N2E2_2488 -1.5 -2.1 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
Pf6N2E2_3504 -1.5 -8.0 Biosynthetic arginine decarboxylase (EC 4.1.1.19) compare
Pf6N2E2_248 -1.4 -6.2 hypothetical protein compare
Pf6N2E2_2472 -1.4 -3.6 hypothetical protein compare
Pf6N2E2_4174 -1.4 -9.3 Methionine ABC transporter substrate-binding protein compare
Pf6N2E2_5182 -1.4 -6.2 Paraquat-inducible protein A compare
Pf6N2E2_5156 -1.4 -2.8 Two-component sensor CbrB: intrcellular carbon:nitrogen balance compare
Pf6N2E2_623 -1.4 -1.2 FIG00954674: hypothetical protein compare
Pf6N2E2_5316 -1.3 -2.4 Periplasmic thiol:disulfide oxidoreductase DsbB, required for DsbA reoxidation compare
Pf6N2E2_2018 -1.3 -2.3 hypothetical protein compare
Pf6N2E2_1783 -1.3 -2.7 Chemotaxis regulator - transmits chemoreceptor signals to flagelllar motor components CheY compare
Pf6N2E2_3373 -1.3 -3.7 Outer membrane lipoprotein SmpA, a component of the essential YaeT outer-membrane protein assembly complex compare
Pf6N2E2_158 -1.3 -7.4 Endonuclease I precursor (EC 3.1.21.1) conserved
Pf6N2E2_5430 -1.2 -7.2 Transglycosylase, Slt family compare
Pf6N2E2_3947 -1.2 -2.6 Cd(II)/Pb(II)-responsive transcriptional regulator compare
Pf6N2E2_4607 -1.2 -3.2 Uracil phosphoribosyltransferase (EC 2.4.2.9) / Pyrimidine operon regulatory protein PyrR compare
Pf6N2E2_5406 -1.2 -1.6 FIG00958224: hypothetical protein compare
Pf6N2E2_4025 -1.2 -1.6 hypothetical protein compare
Pf6N2E2_342 -1.2 -1.5 DNA-binding response regulator compare
Pf6N2E2_4545 -1.1 -2.1 hypothetical protein compare
Pf6N2E2_2471 -1.1 -6.2 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) compare
Pf6N2E2_88 -1.1 -1.6 hypothetical protein compare
Pf6N2E2_3833 -1.1 -3.9 hypothetical protein compare
Pf6N2E2_4206 -1.1 -1.6 Chromosome (plasmid) partitioning protein ParB compare
Pf6N2E2_5414 -1.1 -6.7 Nucleoid-associated protein compare
Pf6N2E2_5640 -1.1 -1.6 FIG00955597: hypothetical protein compare
Pf6N2E2_3132 -1.0 -3.1 FIG00954548: hypothetical protein compare
Pf6N2E2_2381 -1.0 -3.3 Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) compare
Pf6N2E2_2887 -1.0 -3.2 Aldose 1-epimerase compare
Pf6N2E2_4632 -1.0 -7.9 Amine oxidase [flavin-containing] (EC 1.4.3.4) compare
Pf6N2E2_1972 -1.0 -1.6 FIG004780: hypothetical protein in PFGI-1-like cluster compare
Pf6N2E2_5155 -1.0 -2.1 Poly(A) polymerase (EC 2.7.7.19) compare
Pf6N2E2_2523 -1.0 -5.7 Methylthioribose-1-phosphate isomerase (EC 5.3.1.23) compare
Pf6N2E2_1694 -1.0 -1.2 FMN reductase (EC 1.5.1.29) compare
Pf6N2E2_5252 -1.0 -2.3 FIG00956396: hypothetical protein compare
Pf6N2E2_2469 -1.0 -3.0 hypothetical protein compare
Pf6N2E2_4153 -1.0 -1.4 Sensory box histidine kinase compare
Pf6N2E2_4353 -1.0 -3.6 Hydrogen peroxide-inducible genes activator compare
Pf6N2E2_3062 -1.0 -2.3 Membrane-associated zinc metalloprotease compare
Pf6N2E2_2474 -1.0 -5.8 ErfK/YbiS/YcfS/YnhG family protein compare
Pf6N2E2_613 -1.0 -1.3 lipoprotein, putative compare
Pf6N2E2_2106 -0.9 -1.8 hypothetical protein compare
Pf6N2E2_4372 -0.9 -3.3 FIG00460773: hypothetical protein compare
Pf6N2E2_1803 -0.9 -2.9 Polysaccharide deacetylase compare
Pf6N2E2_1162 -0.9 -1.4 Transmembrane amino acid efflux protein compare
Pf6N2E2_4155 -0.9 -5.3 N-acetylmuramoyl-L-alanine amidase (EC 3.5.1.28) compare
Pf6N2E2_28 -0.9 -1.4 4-carboxymuconolactone decarboxylase domain/alkylhydroperoxidase AhpD family core domain protein compare
Pf6N2E2_5014 -0.9 -1.3 Apolipoprotein N-acyltransferase (EC 2.3.1.-) / Copper homeostasis protein CutE compare
Pf6N2E2_712 -0.9 -2.0 hypothetical protein compare
Pf6N2E2_5720 -0.9 -6.4 BarA sensory histidine kinase (= VarS = GacS) compare
Pf6N2E2_2752 -0.9 -4.6 Exported zinc metalloprotease YfgC precursor compare
Pf6N2E2_4276 -0.9 -3.6 Phosphogluconate repressor HexR, RpiR family compare
Pf6N2E2_5536 -0.9 -1.3 Holliday junction DNA helicase RuvA compare
Pf6N2E2_5531 -0.9 -2.2 hypothetical protein compare
Pf6N2E2_1148 -0.9 -2.5 Butyryl-CoA dehydrogenase (EC 1.3.99.2) compare
Pf6N2E2_1028 -0.9 -2.5 Transcriptional regulator, LysR family compare
Pf6N2E2_2755 -0.9 -1.3 Sigma factor RpoE negative regulatory protein RseA compare
Pf6N2E2_537 -0.9 -3.9 Na(+) H(+) antiporter subunit C compare
Pf6N2E2_5668 -0.9 -2.6 Succinylglutamic semialdehyde dehydrogenase (EC 1.2.1.71) compare
Pf6N2E2_672 -0.9 -1.4 ABC-type polar amino acid transport system, ATPase component compare
Pf6N2E2_5759 -0.9 -4.3 DNA recombination protein RmuC compare
Pf6N2E2_4305 -0.8 -1.3 FIG00959590: hypothetical protein compare
Pf6N2E2_21 -0.8 -3.0 Sigma-70 factor FpvI (ECF subfamily), controling pyoverdin biosynthesis compare
Pf6N2E2_1441 -0.8 -1.5 Uncharacterized oxidoreductase ydgJ (EC 1.-.-.-) compare
Pf6N2E2_5402 -0.8 -5.2 ABC transporter for D-Alanine, periplasmic substrate-binding component (from data) compare
Pf6N2E2_5615 -0.8 -4.6 Probable Co/Zn/Cd efflux system membrane fusion protein compare
Pf6N2E2_5669 -0.8 -4.1 Succinylarginine dihydrolase (EC 3.5.3.23) compare
Pf6N2E2_5506 -0.8 -4.9 Exodeoxyribonuclease I (EC 3.1.11.1) compare
Pf6N2E2_2088 -0.8 -0.9 SOS-response repressor and protease LexA (EC 3.4.21.88) compare
Pf6N2E2_3040 -0.8 -3.0 5-nucleotidase SurE (EC 3.1.3.5) compare
Pf6N2E2_2438 -0.8 -1.5 hypothetical protein compare
Pf6N2E2_156 -0.8 -1.4 Carbon storage regulator compare
Pf6N2E2_2313 -0.8 -2.2 Cytochrome c oxidase subunit CcoP (EC 1.9.3.1) compare
Pf6N2E2_2468 -0.8 -3.2 2-dehydropantoate 2-reductase (EC 1.1.1.169) compare
Pf6N2E2_2754 -0.8 -2.9 Sigma factor RpoE negative regulatory protein RseB precursor compare
Pf6N2E2_3885 -0.8 -1.6 3'(2'),5'-bisphosphate nucleotidase (EC 3.1.3.7) compare
Pf6N2E2_1014 -0.8 -1.7 Nitrate/nitrite transporter compare
Pf6N2E2_5614 -0.8 -6.5 RND multidrug efflux transporter; Acriflavin resistance protein compare
Pf6N2E2_2772 -0.8 -3.8 Uracil-DNA glycosylase, family 1 compare
Pf6N2E2_2067 -0.8 -6.3 cis/trans isomerase compare
Pf6N2E2_4609 -0.8 -2.7 UPF0301 protein YqgE compare
Pf6N2E2_3094 -0.8 -3.9 SAM-dependent methyltransferase (EC 2.1.1.-) compare
Pf6N2E2_2022 -0.8 -3.2 BarA-associated response regulator UvrY (= GacA = SirA) compare
Pf6N2E2_4579 -0.8 -2.1 Ribosomal RNA small subunit methyltransferase D (EC 2.1.1.-) compare
Pf6N2E2_6047 -0.8 -1.4 hypothetical protein compare
Pf6N2E2_4661 -0.8 -1.8 KluA regulatory protein compare
Pf6N2E2_4071 -0.7 -1.9 Phosphate transport system regulatory protein PhoU compare
Pf6N2E2_3337 -0.7 -3.2 PTS system, fructose-specific IIB component (EC 2.7.1.69) / PTS system, fructose-specific IIC component (EC 2.7.1.69) compare
Pf6N2E2_3753 -0.7 -5.8 DamX, an inner membrane protein involved in bile resistance compare
Pf6N2E2_159 -0.7 -2.6 DNA damage resistance protein (from data) compare
Pf6N2E2_544 -0.7 -2.4 Short-chain dehydrogenase/reductase SDR compare
Pf6N2E2_1157 -0.7 -1.9 hypothetical protein possibly connected to lactam utilization and allophanate hydrolase compare
Pf6N2E2_4982 -0.7 -3.6 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase (EC 6.3.2.-) compare
Pf6N2E2_1169 -0.7 -1.2 TnpR protein compare
Pf6N2E2_620 -0.7 -3.3 BatD compare
Pf6N2E2_3204 -0.7 -1.7 Rho-specific inhibitor of transcription termination (YaeO) compare
Pf6N2E2_4706 -0.7 -1.2 Electron transfer flavoprotein, beta subunit compare
Pf6N2E2_3944 -0.7 -2.6 Protein of unknown function DUF81 compare
Pf6N2E2_6065 -0.7 -1.1 ABC transporter in pyoverdin gene cluster, periplasmic component compare
Pf6N2E2_4479 -0.7 -1.4 FIG001590: Putative conserved exported protein precursor compare
Pf6N2E2_5986 -0.7 -0.9 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
Pf6N2E2_5785 -0.7 -1.4 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_5433 -0.7 -2.7 FIG137478: Hypothetical protein compare
Pf6N2E2_2367 -0.7 -0.9 hypothetical protein compare
Pf6N2E2_292 -0.7 -3.6 ATP-dependent Clp protease ATP-binding subunit ClpA compare
Pf6N2E2_2467 -0.7 -1.3 5'-nucleotidase (EC 3.1.3.5) compare
Pf6N2E2_1340 -0.7 -1.2 major pilin protein fimA compare
Pf6N2E2_4146 -0.7 -0.8 Membrane lipoprotein lipid attachment site containing protein USSDB6D compare
Pf6N2E2_1545 -0.7 -2.0 N-carbamoylputrescine amidase (EC 3.5.1.53) compare
Pf6N2E2_2201 -0.7 -2.1 Transmembrane regulator protein PrtR compare
Pf6N2E2_1352 -0.7 -1.4 Cation transport ATPase compare
Pf6N2E2_2428 -0.7 -1.4 Thiol-disulfide isomerase and thioredoxins compare
Pf6N2E2_1098 -0.7 -2.1 Arginine/ornithine ABC transporter, periplasmic arginine/ornithine binding protein compare
Pf6N2E2_4147 -0.7 -3.5 Fused spore maturation proteins A and B compare
Pf6N2E2_5967 -0.7 -2.1 L-arabinose 1-dehydrogenase / D-galactose 1-dehydrogenase (EC 1.1.1.46; EC 1.1.1.48) (from data) compare
Pf6N2E2_1095 -0.7 -1.0 Opine oxidase subunit C compare
Pf6N2E2_89 -0.7 -1.1 hypothetical protein compare
Pf6N2E2_5001 -0.7 -1.0 D-alanyl-D-alanine carboxypeptidase (EC 3.4.16.4) compare
Pf6N2E2_4999 -0.7 -3.3 Membrane-bound lytic murein transglycosylase B precursor (EC 3.2.1.-) compare
Pf6N2E2_3461 -0.7 -0.5 Exodeoxyribonuclease V gamma chain (EC 3.1.11.5) compare
Pf6N2E2_5842 -0.6 -1.6 Transcriptional regulator, TetR family compare
Pf6N2E2_1091 -0.6 -1.5 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1; Vanillate O-demethylase oxidoreductase (EC 1.14.13.-) compare
Pf6N2E2_1135 -0.6 -2.5 COGs COG3558 compare
Pf6N2E2_4459 -0.6 -1.4 Transcriptional regulator, GntR family compare


Specific Phenotypes

For 29 genes in this experiment

For stress Lomefloxacin hydrochloride in Pseudomonas fluorescens FW300-N2E2

For stress Lomefloxacin hydrochloride across organisms