Experiment set7IT024 for Methanococcus maripaludis S2

200 most detrimental genes:

gene	name	fitness	t score	description
MMP_RS00185		+0.9	7.1	potassium channel protein
MMP_RS00450		+0.8	1.6	4Fe-4S binding protein
MMP_RS02290		+0.8	4.3	MBL fold metallo-hydrolase
MMP_RS02310		+0.8	1.7	RimK-like ATPgrasp N-terminal domain-containing protein
MMP_RS04145		+0.7	1.7	hypothetical protein
MMP_RS06720		+0.7	5.4	response regulator transcription factor
MMP_RS00655		+0.7	2.5	hypothetical protein
MMP_RS08265		+0.7	2.7	rubrerythrin
MMP_RS00345		+0.7	4.8	DUF2666 domain-containing protein
MMP_RS08930		+0.7	1.7	hypothetical protein
MMP_RS00395		+0.7	1.5	MGMT family protein
MMP_RS07970		+0.7	2.9	hypothetical protein
MMP_RS06315		+0.7	0.8	cobalt-precorrin-7 (C(5))-methyltransferase
MMP_RS06715		+0.6	5.1	cache domain-containing protein
MMP_RS06575		+0.6	2.6	fluoride efflux transporter CrcB
MMP_RS07815		+0.6	1.0	DUF2120 domain-containing protein
MMP_RS03965		+0.6	1.8	hypothetical protein
MMP_RS00120		+0.6	2.6	LysR family transcriptional regulator
MMP_RS08455		+0.5	3.0	multiprotein bridging factor aMBF1
MMP_RS08070		+0.5	2.8	DUF2096 domain-containing protein
MMP_RS06990		+0.5	2.8	CatB-related O-acetyltransferase
MMP_RS02110		+0.5	0.9	hypothetical protein
MMP_RS07960		+0.5	3.7	sugar phosphate isomerase/epimerase
MMP_RS01570		+0.5	1.2	hypothetical protein
MMP_RS07880		+0.5	3.0	AAA family ATPase
MMP_RS08555		+0.5	2.3	hypothetical protein
MMP_RS01675		+0.5	1.2	hypothetical protein
MMP_RS08280		+0.5	2.0	proteasome assembly chaperone family protein
MMP_RS08640		+0.5	3.5	TIM barrel protein
MMP_RS01460		+0.5	1.7	hypothetical protein
MMP_RS06015		+0.5	3.5	flavodoxin family protein
MMP_RS05695		+0.5	3.5	phospholipase D-like domain-containing protein
MMP_RS02680		+0.5	2.6	ABC transporter permease
MMP_RS00295		+0.5	1.4	gamma carbonic anhydrase family protein
MMP_RS03465		+0.5	0.8	adenine phosphoribosyltransferase
MMP_RS00430		+0.5	2.2	hypothetical protein
MMP_RS07775		+0.5	3.1	alanine dehydrogenase
MMP_RS01055		+0.5	1.5	hypothetical protein
MMP_RS08275		+0.5	2.8	hypothetical protein
MMP_RS03785		+0.5	2.2	cupin domain-containing protein
MMP_RS08775		+0.5	2.6	methanogenesis marker 9 domain-containing protein
MMP_RS07620		+0.5	1.5	energy-coupling factor ABC transporter substrate-binding protein
MMP_RS08380		+0.5	2.4	phosphatase PAP2 family protein
MMP_RS02720		+0.4	1.4	molybdate ABC transporter substrate-binding protein
MMP_RS08990		+0.4	2.3	hypothetical protein
MMP_RS03305		+0.4	2.0	winged helix-turn-helix domain-containing protein
MMP_RS05315		+0.4	1.0	hypothetical protein
MMP_RS00085		+0.4	3.2	DNA cytosine methyltransferase
MMP_RS01525		+0.4	1.1	nucleoside-diphosphate kinase
MMP_RS04740		+0.4	1.8	DUF473 domain-containing protein
MMP_RS06500		+0.4	2.7	ATP-binding protein
MMP_RS04165		+0.4	2.1	TetR/AcrR family transcriptional regulator
MMP_RS01630		+0.4	2.7	N-glycosylase/DNA lyase
MMP_RS07885		+0.4	2.0	tripartite tricarboxylate transporter permease
MMP_RS06735		+0.4	2.0	class I SAM-dependent rRNA methyltransferase
MMP_RS04735		+0.4	1.7	tautomerase family protein
MMP_RS03065		+0.4	1.2	AzlC family ABC transporter permease
MMP_RS02815		+0.4	1.4	hypothetical protein
MMP_RS00155		+0.4	2.6	heavy metal-binding domain-containing protein
MMP_RS03895		+0.4	1.6	hypothetical protein
MMP_RS08760		+0.4	1.5	hypothetical protein
MMP_RS06325		+0.4	0.8	hypothetical protein
MMP_RS02315		+0.4	2.3	RimK family alpha-L-glutamate ligase
MMP_RS08400		+0.4	1.4	MJ0307 family thioredoxin
MMP_RS08130		+0.4	3.0	IGHMBP2 family helicase
MMP_RS06570		+0.4	1.4	DUF190 domain-containing protein
MMP_RS02385		+0.4	1.9	ATP-binding protein
MMP_RS08665		+0.4	3.0	hypothetical protein
MMP_RS05715		+0.4	2.2	hypothetical protein
MMP_RS00335		+0.4	1.8	5-amino-6-(D-ribitylamino)uracil--L-tyrosine 4-hydroxyphenyl transferase CofH
MMP_RS09035		+0.4	1.7	hypothetical protein
MMP_RS06965		+0.4	1.6	TIGR04014 family B12-binding domain/radical SAM domain-containing protein
MMP_RS00940		+0.4	1.9	daunorubicin resistance protein DrrA family ABC transporter ATP-binding protein
MMP_RS00290		+0.4	2.0	hypothetical protein
MMP_RS01130		+0.4	2.2	flavoprotein
MMP_RS09060		+0.4	2.6	hypothetical protein
MMP_RS08075		+0.4	2.5	DUF749 domain-containing protein
MMP_RS08620		+0.4	1.8	flagellar accessory protein FlaH
MMP_RS05975		+0.4	0.8	hypothetical protein
MMP_RS01620		+0.4	2.0	hypothetical protein
MMP_RS08390		+0.4	1.3	DUF5400 domain-containing protein
MMP_RS08480		+0.4	2.3	molybdate ABC transporter substrate-binding protein
MMP_RS02915		+0.4	1.9	amino acid ABC transporter permease
MMP_RS08285		+0.3	1.9	serine/threonine protein kinase
MMP_RS07770		+0.3	1.5	alanine racemase
MMP_RS04790		+0.3	2.3	4-hydroxy-tetrahydrodipicolinate reductase
MMP_RS00400		+0.3	1.2	tributyrin esterase
MMP_RS04100		+0.3	1.5	hypothetical protein
MMP_RS07125		+0.3	1.1	coenzyme F420-reducing hydrogenase FrhD protein
MMP_RS06225		+0.3	1.4	DNA double-strand break repair nuclease NurA
MMP_RS06930		+0.3	2.1	MBL fold metallo-hydrolase
MMP_RS08410		+0.3	1.6	DUF169 domain-containing protein
MMP_RS08850		+0.3	2.6	hypothetical protein
MMP_RS02770		+0.3	1.3	hypothetical protein
MMP_RS04205		+0.3	1.6	carboxymuconolactone decarboxylase family protein
MMP_RS06655		+0.3	2.3	glycoside hydrolase family 15 protein
MMP_RS07925		+0.3	1.3	haloacid dehalogenase
MMP_RS09065		+0.3	2.4	hypothetical protein
MMP_RS08485		+0.3	2.1	tungstate ABC transporter substrate-binding protein WtpA
MMP_RS08250		+0.3	2.1	pyruvate kinase
MMP_RS00235		+0.3	2.0	HDIG domain-containing protein
MMP_RS08175		+0.3	1.5	7-cyano-7-deazaguanine synthase
MMP_RS02935		+0.3	1.6	A24 family peptidase
MMP_RS07890		+0.3	1.0	OB-fold nucleic acid binding domain-containing protein
MMP_RS01125		+0.3	1.7	thioredoxin family protein
MMP_RS00660		+0.3	2.2	alkaline phosphatase family protein
MMP_RS02790		+0.3	0.5	class III signal peptide-containing protein
MMP_RS08845		+0.3	1.5	archaellum operon transcriptional activator EarA family protein
MMP_RS00795		+0.3	1.6	formate dehydrogenase H subunit alpha selenocysteine-containing
MMP_RS00380		+0.3	1.3	P-II family nitrogen regulator
MMP_RS02695		+0.3	1.9	formylmethanofuran dehydrogenase subunit A
MMP_RS06140		+0.3	1.4	radical SAM protein
MMP_RS03330		+0.3	2.1	rubrerythrin family protein
MMP_RS02475		+0.3	1.0	hypothetical protein
MMP_RS07915		+0.3	1.0	DUF4870 domain-containing protein
MMP_RS00385		+0.3	1.8	P-II family nitrogen regulator
MMP_RS05235		+0.3	1.7	exodeoxyribonuclease III
MMP_RS08670		+0.3	1.2	metallophosphoesterase
MMP_RS08580		+0.3	0.5	flagellin
MMP_RS08325		+0.3	1.8	hypothetical protein
MMP_RS00975		+0.3	2.0	HD domain-containing protein
MMP_RS00625		+0.3	1.4	hypothetical protein
MMP_RS08700		+0.3	1.5	hypothetical protein
MMP_RS07900		+0.3	0.9	YeeE/YedE family protein
MMP_RS08975		+0.3	1.7	hypothetical protein
MMP_RS00390		+0.3	1.6	ammonium transporter
MMP_RS02410		+0.3	1.0	ABC transporter substrate-binding protein
MMP_RS05270		+0.3	2.0	PEGA domain-containing protein
MMP_RS01580		+0.3	1.8	PQQ-binding-like beta-propeller repeat protein
MMP_RS06520		+0.3	2.0	DUF1786 domain-containing protein
MMP_RS08160		+0.3	1.5	EamA family transporter
MMP_RS01060		+0.3	2.0	calcium/sodium antiporter
MMP_RS01145		+0.3	1.8	ABC transporter ATP-binding protein
MMP_RS02375		+0.3	1.9	hypothetical protein
MMP_RS07805		+0.3	1.5	ABC transporter permease
MMP_RS00545		+0.3	1.3	XRE family transcriptional regulator
MMP_RS08405		+0.3	1.6	MFS transporter
MMP_RS08625		+0.3	1.5	type II/IV secretion system ATPase subunit
MMP_RS09030		+0.3	1.1	hypothetical protein
MMP_RS08310		+0.3	0.7	TMEM165/GDT1 family protein
MMP_RS00375		+0.3	1.7	ammonium transporter
MMP_RS04195		+0.3	0.7	flavodoxin
MMP_RS02705		+0.2	1.4	formylmethanofuran dehydrogenase subunit B
MMP_RS05675		+0.2	1.0	phosphate ABC transporter ATP-binding protein PstB
MMP_RS08610		+0.2	1.7	flagellar protein F
MMP_RS03885		+0.2	1.4	tyrosine-type recombinase/integrase
MMP_RS00945		+0.2	0.4	PadR family transcriptional regulator
MMP_RS00280		+0.2	1.5	DUF2118 domain-containing protein
MMP_RS01980		+0.2	1.8	trimeric intracellular cation channel family protein
MMP_RS05970		+0.2	0.7	class II SORL domain-containing protein
MMP_RS01985		+0.2	1.3	F420-dependent methylenetetrahydromethanopterin dehydrogenase
MMP_RS04520		+0.2	0.8	nucleoside deaminase
MMP_RS02425		+0.2	1.4	hypothetical protein
MMP_RS06280		+0.2	1.3	alpha-glucan family phosphorylase
MMP_RS09055		+0.2	0.3	CAP domain-containing protein
MMP_RS02215		+0.2	1.8	ECF transporter S component
MMP_RS04610		+0.2	0.6	Dabb family protein
MMP_RS00950		+0.2	1.1	site-2 protease family protein
MMP_RS07550		+0.2	1.6	L-serine ammonia-lyase iron-sulfur-dependent subunit alpha
MMP_RS06660		+0.2	1.3	glycosyltransferase family 4 protein
MMP_RS03220		+0.2	0.8	RNA 2' 3'-cyclic phosphodiesterase
MMP_RS05140		+0.2	0.7	helix-turn-helix transcriptional regulator
MMP_RS06910		+0.2	1.1	RlmF-related methyltransferase
MMP_RS05895		+0.2	1.8	metallophosphoesterase
MMP_RS08085		+0.2	1.4	hypothetical protein
MMP_RS08370		+0.2	0.2	cation:proton antiporter subunit C
MMP_RS03555		+0.2	1.2	transcriptional regulator
MMP_RS01120		+0.2	1.3	permease
MMP_RS06490		+0.2	1.1	hypothetical protein
MMP_RS07715		+0.2	1.6	YfcE family phosphodiesterase
MMP_RS09050		+0.2	0.7	CAP domain-containing protein
MMP_RS01105		+0.2	1.0	hypothetical protein
MMP_RS08770		+0.2	1.2	hypothetical protein
MMP_RS01485		+0.2	1.3	right-handed parallel beta-helix repeat-containing protein
MMP_RS02000		+0.2	1.0	radical SAM protein
MMP_RS07590		+0.2	1.6	hypothetical protein
MMP_RS03740		+0.2	0.8	indolepyruvate oxidoreductase subunit beta
MMP_RS03350		+0.2	0.9	winged helix-turn-helix domain-containing protein
MMP_RS06485		+0.2	0.3	zinc ribbon domain-containing protein
MMP_RS06555		+0.2	0.8	cupin domain-containing protein
MMP_RS08315		+0.2	0.8	S-methyl-5-thioribose-1-phosphate isomerase
MMP_RS08490		+0.2	1.8	hypothetical protein
MMP_RS03630		+0.2	1.6	hypothetical protein
MMP_RS05095		+0.2	1.3	CO dehydrogenase/acetyl-CoA synthase complex subunit epsilon
MMP_RS01870		+0.2	1.3	acyl-CoA dehydratase activase
MMP_RS04530		+0.2	1.5	ABC transporter permease
MMP_RS02510		+0.2	1.5	site-specific integrase
MMP_RS03320		+0.2	0.7	metal-dependent transcriptional regulator
MMP_RS03280		+0.2	1.4	pyridoxamine 5'-phosphate oxidase family protein
MMP_RS00540		+0.2	0.9	PLP-dependent aminotransferase family protein
MMP_RS01200		+0.2	0.7	hypothetical protein
MMP_RS07765		+0.2	1.4	sodium:alanine symporter family protein
MMP_RS04965		+0.2	1.2	thioredoxin family protein
MMP_RS01110		+0.2	0.9	FmdE family protein
MMP_RS00855		+0.2	1.0	DUF367 family protein
MMP_RS04785		+0.2	1.7	hypothetical protein
MMP_RS05700		+0.2	1.3	TfuA-related McrA-glycine thioamidation protein
MMP_RS06080		+0.2	1.5	radical SAM protein
MMP_RS08260		+0.2	1.3	DUF99 family protein
MMP_RS08205		+0.2	1.4	stage II sporulation protein M

Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in iron experiments

For iron Iron (II) chloride tetrahydrate across organisms