Experiment set7IT021 for Klebsiella michiganensis M5al

Compare to:

LB with Fusidic acid sodium salt 0.5 mg/ml

200 most detrimental genes:

  gene name fitness t score description  
BWI76_RS27680 +3.7 4.5 TetR family transcriptional regulator compare
BWI76_RS00140 +1.7 3.0 phosphate transport system regulator PhoU compare
BWI76_RS16360 +1.6 3.5 electron transport complex subunit RsxB compare
BWI76_RS04050 +1.5 1.8 hydroxamate siderophore iron reductase FhuF compare
BWI76_RS16920 +1.5 4.1 3-(2,3-dihydroxyphenyl)propionate dioxygenase compare
BWI76_RS00180 +1.4 4.1 F0F1 ATP synthase subunit epsilon compare
BWI76_RS07465 +1.3 12.4 TetR family transcriptional regulator compare
BWI76_RS10835 +1.3 2.3 hypothetical protein compare
BWI76_RS06635 +1.2 1.3 methylated-DNA--protein-cysteine methyltransferase compare
BWI76_RS09730 +1.1 1.6 pyruvate formate lyase 1-activating protein compare
BWI76_RS07865 +1.1 3.9 methylthioribulose 1-phosphate dehydratase compare
BWI76_RS12495 +1.1 3.0 2-Cys peroxiredoxin compare
BWI76_RS18755 +1.0 1.6 adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase compare
BWI76_RS04525 +1.0 2.8 4-hydroxythreonine-4-phosphate dehydrogenase PdxA compare
BWI76_RS24885 +1.0 1.4 PTS galactitol transporter subunit IIB compare
BWI76_RS24070 +0.9 3.0 16S rRNA (uracil(1498)-N(3))-methyltransferase compare
BWI76_RS26890 +0.9 1.2 hypothetical protein compare
BWI76_RS10305 +0.9 6.0 transposase compare
BWI76_RS00480 +0.9 2.5 hypothetical protein compare
BWI76_RS20930 +0.9 2.7 arsenate reductase (glutaredoxin) compare
BWI76_RS10060 +0.9 2.0 acylphosphatase compare
BWI76_RS24945 +0.9 1.7 glutamine amidotransferase compare
BWI76_RS24485 +0.9 2.2 bifunctional dihydroneopterin aldolase/7,8-dihydroneopterin epimerase compare
BWI76_RS16375 +0.8 1.7 electron transport complex subunit G compare
BWI76_RS09560 +0.8 1.6 DoxX family membrane protein compare
BWI76_RS06680 +0.8 1.4 hypothetical protein compare
BWI76_RS11440 +0.8 1.2 hypothetical protein compare
BWI76_RS21685 +0.8 1.4 hypothetical protein compare
BWI76_RS11820 +0.8 1.4 short-chain dehydrogenase/reductase SDR compare
BWI76_RS16030 +0.8 1.1 malonate decarboxylase acyl carrier protein compare
BWI76_RS16815 +0.8 2.5 periplasmic binding protein compare
BWI76_RS10500 +0.7 2.0 flavoprotein monooxygenase compare
BWI76_RS10295 +0.7 1.8 short chain dehydrogenase/reductase family oxidoreductase compare
BWI76_RS11580 +0.7 1.7 L-asparaginase 1 compare
BWI76_RS00240 +0.7 1.5 FMN-binding protein MioC compare
BWI76_RS14415 +0.7 1.6 transcriptional regulator, TetR family protein compare
BWI76_RS14625 +0.7 1.3 protein TolA compare
BWI76_RS21340 +0.7 1.8 SoxR reducing system protein RseC compare
BWI76_RS23015 +0.7 1.6 cobalt transporter ATP-binding subunit compare
BWI76_RS09760 +0.7 2.4 3-phosphoshikimate 1-carboxyvinyltransferase compare
BWI76_RS22095 +0.7 2.8 multidrug export protein EmrA compare
BWI76_RS26065 +0.7 1.8 phosphoglycolate phosphatase compare
BWI76_RS18195 +0.7 3.4 tRNA 5-methoxyuridine(34)/uridine 5-oxyacetic acid(34) synthase CmoB compare
BWI76_RS10910 +0.7 2.5 hypothetical protein compare
BWI76_RS20750 +0.7 1.2 carboxysome structural protein EutK compare
BWI76_RS01775 +0.7 1.4 hypothetical protein compare
BWI76_RS05970 +0.7 2.6 hypothetical protein compare
BWI76_RS13515 +0.7 2.1 amino acid permease compare
BWI76_RS21345 +0.7 2.1 sigma-E factor regulatory protein RseB compare
BWI76_RS11285 +0.7 1.5 transcriptional regulator compare
BWI76_RS24575 +0.6 1.4 hypothetical protein compare
BWI76_RS06935 +0.6 3.0 co-chaperone YbbN compare
BWI76_RS16425 +0.6 1.1 hypothetical protein compare
BWI76_RS13320 +0.6 2.4 putative LpxA-like enzyme compare
BWI76_RS12235 +0.6 0.6 hypothetical protein compare
BWI76_RS05525 +0.6 1.7 glycerophosphodiester phosphodiesterase compare
BWI76_RS13955 +0.6 1.2 hypothetical protein compare
BWI76_RS14050 +0.6 1.9 AP endonuclease, family 2 compare
BWI76_RS04095 +0.6 2.4 dUMP phosphatase compare
BWI76_RS07500 +0.6 2.0 RND transporter MFP subunit compare
BWI76_RS20375 +0.6 1.3 membrane protein compare
BWI76_RS04060 +0.6 1.2 hypothetical protein compare
BWI76_RS08615 +0.6 2.5 galactokinase compare
BWI76_RS17890 +0.6 1.4 PTS mannose transporter subunit EIIAB compare
BWI76_RS13820 +0.6 1.1 hypothetical protein compare
BWI76_RS17375 +0.6 1.5 nitrate ABC transporter, permease protein compare
BWI76_RS12675 +0.6 2.8 putative UV protection and mutation protein compare
BWI76_RS01205 +0.6 1.9 DUF484 family protein compare
BWI76_RS06785 +0.6 2.5 DNA-binding transcriptional repressor AcrR compare
BWI76_RS14935 +0.6 1.0 NIPSNAP family containing protein compare
BWI76_RS13785 +0.6 1.4 ABC transporter permease compare
BWI76_RS04145 +0.6 2.6 purine-nucleoside phosphorylase compare
BWI76_RS09455 +0.6 2.1 YbjN domain-containing protein compare
BWI76_RS09540 +0.6 2.1 hypothetical protein compare
BWI76_RS19700 +0.6 1.6 deoxyribonuclease IV compare
BWI76_RS14320 +0.6 1.3 hypothetical protein compare
BWI76_RS11235 +0.6 1.0 hypothetical protein compare
BWI76_RS10035 +0.6 1.3 hypothetical protein compare
BWI76_RS20435 +0.6 1.3 chorismate synthase compare
BWI76_RS25245 +0.6 2.3 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase compare
BWI76_RS07470 +0.6 1.2 MBL fold metallo-hydrolase compare
BWI76_RS11040 +0.6 2.2 ribonuclease E compare
BWI76_RS19360 +0.6 1.5 glucose dehydrogenase compare
BWI76_RS01540 +0.6 1.5 thiamine biosynthesis protein ThiS compare
BWI76_RS11735 +0.6 1.9 PTS N,N'-diacetylchitobiose transporter subunit IIA compare
BWI76_RS08330 +0.6 1.2 hypothetical protein compare
BWI76_RS14040 +0.6 1.2 thiaminase compare
BWI76_RS09515 +0.6 1.2 arginine ABC transporter substrate-binding protein compare
BWI76_RS01135 +0.6 3.0 lipopolysaccharide N-acetylmannosaminouronosyltransferase compare
BWI76_RS04165 +0.6 2.1 DNA repair protein RadA compare
BWI76_RS03025 +0.6 1.8 N-acetyltransferase compare
BWI76_RS26235 +0.6 2.0 gluconate transporter compare
BWI76_RS20000 +0.6 1.1 competence/damage-inducible protein A compare
BWI76_RS04655 +0.6 1.8 shikimate dehydrogenase compare
BWI76_RS02730 +0.6 3.0 2',3'-cyclic-nucleotide 2'-phosphodiesterase compare
BWI76_RS13135 +0.6 1.9 3-oxoadipyl-CoA thiolase compare
BWI76_RS03040 +0.6 1.7 leucyl aminopeptidase compare
BWI76_RS19900 +0.5 2.5 FAD:protein FMN transferase compare
BWI76_RS21165 +0.5 1.4 Fe-S cluster assembly transcriptional regulator IscR compare
BWI76_RS14280 +0.5 1.8 hypothetical protein compare
BWI76_RS15030 +0.5 0.9 ABC transporter compare
BWI76_RS06015 +0.5 0.9 hypothetical protein compare
BWI76_RS12620 +0.5 2.1 2-nitropropane dioxygenase compare
BWI76_RS11520 +0.5 0.9 hypothetical protein compare
BWI76_RS24965 +0.5 2.5 SCP2 domain-containing protein compare
BWI76_RS11675 +0.5 1.8 arginine N-succinyltransferase compare
BWI76_RS14410 +0.5 1.7 hypothetical protein compare
BWI76_RS07540 +0.5 1.8 dipeptide ABC transporter ATP-binding protein DppD compare
BWI76_RS13240 +0.5 1.0 hypothetical protein compare
BWI76_RS18780 +0.5 1.5 D-alanyl-D-alanine carboxypeptidase compare
BWI76_RS00715 +0.5 1.6 two-component sensor histidine kinase compare
BWI76_RS13025 +0.5 1.3 histidine phosphatase family protein compare
BWI76_RS16195 +0.5 0.9 hypothetical protein compare
BWI76_RS23320 +0.5 1.0 hypothetical protein compare
BWI76_RS09755 +0.5 3.2 phosphoserine transaminase compare
BWI76_RS16935 +0.5 0.9 shikimate dehydrogenase compare
BWI76_RS21565 +0.5 0.8 outer membrane protein assembly factor BamE compare
BWI76_RS11985 +0.5 2.1 hypothetical protein compare
BWI76_RS01090 +0.5 2.5 UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing) compare
BWI76_RS23895 +0.5 0.8 Xaa-Pro aminopeptidase compare
BWI76_RS12445 +0.5 1.6 phage shock protein operon transcriptional activator compare
BWI76_RS19240 +0.5 1.2 ABC transporter substrate-binding protein compare
BWI76_RS02710 +0.5 2.9 EamA family transporter compare
BWI76_RS24500 +0.5 1.6 urease subunit gamma compare
BWI76_RS17945 +0.5 0.5 hypothetical protein compare
BWI76_RS13445 +0.5 0.9 alpha/beta hydrolase compare
BWI76_RS05425 +0.5 2.1 EEP domain-containing protein compare
BWI76_RS13260 +0.5 2.6 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase compare
BWI76_RS07460 +0.5 1.7 hypothetical protein compare
BWI76_RS18410 +0.5 1.4 drug/metabolite exporter YedA compare
BWI76_RS27950 +0.5 2.0 transcriptional regulator compare
BWI76_RS05335 +0.5 1.3 copper homeostasis/adhesion lipoprotein NlpE compare
BWI76_RS26290 +0.5 2.0 glycerol-3-phosphate ABC transporter ATP-binding protein compare
BWI76_RS01380 +0.5 1.1 YigZ family protein compare
BWI76_RS05550 +0.5 2.8 fermentation/respiration switch protein compare
BWI76_RS02610 +0.5 2.2 transcriptional regulator compare
BWI76_RS13070 +0.5 2.1 hypothetical protein compare
BWI76_RS21570 +0.5 1.1 RnfH family protein compare
BWI76_RS23360 +0.5 1.8 diaminopimelate decarboxylase compare
BWI76_RS15120 +0.5 1.5 hypothetical protein compare
BWI76_RS05235 +0.5 0.8 hypothetical protein compare
BWI76_RS19050 +0.5 3.4 NAD(P)-dependent oxidoreductase compare
BWI76_RS08820 +0.5 2.1 molybdenum cofactor biosynthesis protein compare
BWI76_RS07200 +0.5 2.3 MFS transporter compare
BWI76_RS23755 +0.5 2.6 transcriptional regulator compare
BWI76_RS19920 +0.5 3.0 hybrid sensor histidine kinase/response regulator compare
BWI76_RS05010 +0.5 1.0 tRNA glutamyl-Q synthetase compare
BWI76_RS15285 +0.5 1.6 stress protection protein MarC compare
BWI76_RS10725 +0.5 0.8 hypothetical protein compare
BWI76_RS18355 +0.5 2.7 amino acid ABC transporter permease compare
BWI76_RS16655 +0.5 1.6 CatA-like O-acetyltransferase compare
BWI76_RS26685 +0.5 2.8 glutathione-disulfide reductase compare
BWI76_RS21810 +0.5 0.7 universal stress protein compare
BWI76_RS05075 +0.5 0.7 type II secretion system protein GspG compare
BWI76_RS09595 +0.5 3.2 macrolide transporter subunit MacA compare
BWI76_RS14615 +0.5 0.8 hypothetical protein compare
BWI76_RS15960 +0.5 1.4 LysR family transcriptional regulator compare
BWI76_RS24080 +0.5 1.0 DUF179 domain-containing protein compare
BWI76_RS00505 +0.5 2.3 PTS system, sorbose-specific IIB component compare
BWI76_RS16880 +0.5 2.5 GlpE family protein compare
BWI76_RS15930 +0.5 1.0 dimethylsulfoxide reductase, chain B compare
BWI76_RS02740 +0.5 1.9 putative transcriptional regulator compare
BWI76_RS27915 +0.5 1.3 YceK/YidQ family lipoprotein compare
BWI76_RS20995 +0.4 2.2 RNA degradosome polyphosphate kinase compare
BWI76_RS24740 +0.4 2.4 GntR family transcriptional regulator compare
BWI76_RS00745 +0.4 2.1 1,4-dihydroxy-2-naphthoate polyprenyltransferase compare
BWI76_RS27255 +0.4 2.5 2-amino-3-ketobutyrate coenzyme A ligase (EC 2.3.1.29) (from data) compare
BWI76_RS01815 +0.4 2.5 phosphate-starvation-inducible protein PsiE compare
BWI76_RS09670 +0.4 1.8 recombination factor protein RarA compare
BWI76_RS15915 +0.4 2.6 YnfC family lipoprotein compare
BWI76_RS16025 +0.4 0.9 triphosphoribosyl-dephospho-CoA synthase compare
BWI76_RS13045 +0.4 1.9 hypothetical protein compare
BWI76_RS26980 +0.4 1.4 cold-shock protein compare
BWI76_RS13170 +0.4 1.3 methyltransferase compare
BWI76_RS17920 +0.4 1.6 23S rRNA (guanine(745)-N(1))-methyltransferase compare
BWI76_RS26015 +0.4 1.4 DUF2559 domain-containing protein compare
BWI76_RS21290 +0.4 2.0 DNA-binding transcriptional regulator compare
BWI76_RS08770 +0.4 1.6 malonyl-ACP O-methyltransferase BioC compare
BWI76_RS24035 +0.4 2.0 hypothetical protein compare
BWI76_RS12170 +0.4 1.6 hypothetical protein compare
BWI76_RS14075 +0.4 0.8 TetR family transcriptional regulator compare
BWI76_RS27550 +0.4 1.4 hypothetical protein compare
BWI76_RS26370 +0.4 2.7 aromatic amino acid transporter compare
BWI76_RS14805 +0.4 0.7 hypothetical protein compare
BWI76_RS11915 +0.4 2.4 protease SohB compare
BWI76_RS05680 +0.4 1.9 LacI family transcriptional regulator compare
BWI76_RS11490 +0.4 2.2 MltA-interacting protein MipA compare
BWI76_RS21390 +0.4 1.7 thiol disulfide reductase thioredoxin compare
BWI76_RS14330 +0.4 1.7 IS3 family transposase compare
BWI76_RS26410 +0.4 0.4 membrane protein compare
BWI76_RS10745 +0.4 0.6 hypothetical protein compare
BWI76_RS21040 +0.4 1.6 peptidase M4 compare
BWI76_RS10700 +0.4 1.3 XRE family transcriptional regulator compare
BWI76_RS14145 +0.4 1.9 dihydrolipoyl dehydrogenase compare
BWI76_RS16235 +0.4 1.8 membrane protein compare
BWI76_RS22410 +0.4 1.4 PTS lactose/cellobiose transporter subunit IIA compare
BWI76_RS01835 +0.4 1.5 chemotaxis protein CheW compare
BWI76_RS15305 +0.4 1.0 O-acetylserine/cysteine exporter compare
BWI76_RS25645 +0.4 2.0 shikimate dehydrogenase compare
BWI76_RS19470 +0.4 1.1 DNA-binding response regulator compare


Specific Phenotypes

None in this experiment

For Klebsiella michiganensis M5al in stress experiments

For stress Fusidic acid sodium salt across organisms