Experiment set7IT019 for Pseudomonas fluorescens FW300-N2E2

Compare to:

LB with sodium fluoride 15 mM

200 most important genes:

  gene name fitness t score description  
Pf6N2E2_300 -5.4 -5.2 CrcB protein conserved
Pf6N2E2_773 -4.7 -9.4 Undecaprenyl-diphosphatase (EC 3.6.1.27) compare
Pf6N2E2_4352 -2.2 -4.3 ATP-dependent DNA helicase RecG (EC 3.6.1.-) compare
Pf6N2E2_4072 -2.0 -5.8 Phosphate transport ATP-binding protein PstB (TC 3.A.1.7.1) compare
Pf6N2E2_178 -2.0 -1.8 Phenylalanyl-tRNA synthetase beta chain (EC 6.1.1.20) compare
Pf6N2E2_2217 -1.8 -5.3 ATP-dependent Clp protease ATP-binding subunit ClpX compare
Pf6N2E2_2003 -1.6 -2.4 hypothetical protein compare
Pf6N2E2_2756 -1.6 -6.5 RNA polymerase sigma-H factor AlgT compare
Pf6N2E2_4369 -1.4 -2.3 Exodeoxyribonuclease III (EC 3.1.11.2) compare
Pf6N2E2_5406 -1.4 -3.2 FIG00958224: hypothetical protein compare
Pf6N2E2_3612 -1.4 -3.1 HflK protein compare
Pf6N2E2_4077 -1.4 -1.8 cytosolic long-chain acyl-CoA thioester hydrolase family protein compare
Pf6N2E2_3062 -1.3 -4.6 Membrane-associated zinc metalloprotease compare
Pf6N2E2_2675 -1.2 -1.4 ATP-dependent RNA helicase SrmB compare
Pf6N2E2_309 -1.2 -2.0 FIG00957702: hypothetical protein compare
Pf6N2E2_4372 -1.2 -3.8 FIG00460773: hypothetical protein compare
Pf6N2E2_2218 -1.2 -4.0 ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92) compare
Pf6N2E2_4638 -1.2 -2.8 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) compare
Pf6N2E2_1083 -1.2 -1.6 hypothetical protein compare
Pf6N2E2_2080 -1.2 -1.6 hypothetical protein compare
Pf6N2E2_5455 -1.1 -3.3 hypothetical protein compare
Pf6N2E2_2018 -1.1 -2.6 hypothetical protein compare
Pf6N2E2_4092 -1.1 -2.6 FIG00954395: hypothetical protein compare
Pf6N2E2_2438 -1.0 -2.1 hypothetical protein compare
Pf6N2E2_3351 -1.0 -3.7 tRNA pseudouridine synthase B (EC 4.2.1.70) compare
Pf6N2E2_3248 -1.0 -3.6 Probable transmembrane protein compare
Pf6N2E2_4416 -1.0 -2.1 Tyrosine recombinase XerC compare
Pf6N2E2_4075 -1.0 -3.0 Phosphate ABC transporter, periplasmic phosphate-binding protein PstS (TC 3.A.1.7.1) compare
Pf6N2E2_4074 -1.0 -7.4 Phosphate transport system permease protein PstC (TC 3.A.1.7.1) compare
Pf6N2E2_623 -1.0 -1.1 FIG00954674: hypothetical protein compare
Pf6N2E2_5255 -1.0 -6.7 Outer membrane stress sensor protease DegS compare
Pf6N2E2_1490 -1.0 -1.9 hypothetical protein compare
Pf6N2E2_4743 -0.9 -1.1 hypothetical protein compare
Pf6N2E2_3611 -0.9 -1.3 HflC protein compare
Pf6N2E2_2264 -0.9 -2.7 NADPH dependent preQ0 reductase (EC 1.7.1.13) compare
Pf6N2E2_1545 -0.9 -2.8 N-carbamoylputrescine amidase (EC 3.5.1.53) compare
Pf6N2E2_476 -0.9 -2.7 Permease of the drug/metabolite transporter (DMT) superfamily compare
Pf6N2E2_3876 -0.9 -3.6 Agmatine deiminase (EC 3.5.3.12) compare
Pf6N2E2_1596 -0.9 -1.5 Periplasmic nitrate reductase component NapD compare
Pf6N2E2_469 -0.9 -1.2 lipoprotein, putative compare
Pf6N2E2_4531 -0.9 -1.4 hypothetical protein compare
Pf6N2E2_5178 -0.9 -1.6 CDP-diacylglycerol--serine O-phosphatidyltransferase (EC 2.7.8.8) compare
Pf6N2E2_3134 -0.8 -1.0 hypothetical protein compare
Pf6N2E2_3763 -0.8 -1.7 hypothetical protein compare
Pf6N2E2_4706 -0.8 -1.8 Electron transfer flavoprotein, beta subunit compare
Pf6N2E2_1705 -0.8 -1.4 Branched-chain amino acid transport ATP-binding protein LivG (TC 3.A.1.4.1) compare
Pf6N2E2_2064 -0.8 -1.9 Cobalt-precorrin-3b C17-methyltransferase compare
Pf6N2E2_3947 -0.8 -1.2 Cd(II)/Pb(II)-responsive transcriptional regulator compare
Pf6N2E2_4364 -0.8 -2.5 Protein YicC compare
Pf6N2E2_1340 -0.8 -1.3 major pilin protein fimA compare
Pf6N2E2_5262 -0.8 -1.7 FKBP-type peptidyl-prolyl cis-trans isomerase SlyD (EC 5.2.1.8) compare
Pf6N2E2_3074 -0.8 -1.4 FIG00960973: hypothetical protein compare
Pf6N2E2_5496 -0.8 -2.5 FIG00953991: hypothetical protein compare
Pf6N2E2_1089 -0.8 -1.9 Delta 1-piperideine-2-carboxylate reductase (EC 1.5.1.21) / Delta 1-pyrroline-2-carboxylate reductase (EC 1.5.1.1) compare
Pf6N2E2_423 -0.8 -1.6 Putative phosphatase YfbT compare
Pf6N2E2_5741 -0.8 -3.8 L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81) compare
Pf6N2E2_1987 -0.8 -1.3 hypothetical protein compare
Pf6N2E2_3638 -0.8 -2.2 hypothetical protein compare
Pf6N2E2_5571 -0.8 -1.6 hypothetical protein compare
Pf6N2E2_5740 -0.8 -2.7 Adenosylcobinamide-phosphate synthase (EC 6.3.1.10) compare
Pf6N2E2_2693 -0.7 -1.2 3-oxoacyl-[acyl-carrier-protein] synthase, KASIII (EC 2.3.1.180) compare
Pf6N2E2_620 -0.7 -4.3 BatD compare
Pf6N2E2_3477 -0.7 -1.7 2-Oxobutyrate oxidase, putative compare
Pf6N2E2_3529 -0.7 -1.7 Toxin A compare
Pf6N2E2_4762 -0.7 -2.2 Biotin synthesis protein BioH compare
Pf6N2E2_5261 -0.7 -0.9 FIG00956983: hypothetical protein compare
Pf6N2E2_5830 -0.7 -1.7 FIG00960829: hypothetical protein compare
Pf6N2E2_4272 -0.7 -2.3 putative membrane protein compare
Pf6N2E2_138 -0.7 -2.4 Alpha/beta hydrolase fold (EC 3.8.1.5) compare
Pf6N2E2_5898 -0.7 -2.1 Integral membrane protein compare
Pf6N2E2_1248 -0.7 -1.5 MutT/nudix family protein compare
Pf6N2E2_1504 -0.7 -2.2 putative 2-pyrone-4,6-dicarboxylic acid hydrolase compare
Pf6N2E2_579 -0.7 -0.8 FIG00962753: hypothetical protein compare
Pf6N2E2_3282 -0.7 -1.7 FIG005080: Possible exported protein compare
Pf6N2E2_3406 -0.7 -2.3 putative ABC transporter ATP-binding protein compare
Pf6N2E2_1323 -0.7 -2.2 3-oxoacyl-[acyl-carrier protein] reductase (EC 1.1.1.100) compare
Pf6N2E2_4160 -0.7 -1.0 Cytochrome c5 compare
Pf6N2E2_3738 -0.7 -2.3 General secretion pathway protein L compare
Pf6N2E2_2320 -0.7 -2.1 Heavy-metal-associated domain (N-terminus) and membrane-bounded cytochrome biogenesis cycZ-like domain, possible membrane copper tolerance protein compare
Pf6N2E2_1584 -0.7 -2.1 Transcriptional regulator, MarR family / Acetyltransferase (GNAT) compare
Pf6N2E2_5846 -0.7 -5.1 Nucleoside ABC transporter, periplasmic nucleoside-binding protein compare
Pf6N2E2_5510 -0.7 -2.1 FIG00955324: hypothetical protein compare
Pf6N2E2_987 -0.7 -1.5 hypothetical protein compare
Pf6N2E2_5679 -0.7 -2.9 hypothetical protein compare
Pf6N2E2_160 -0.7 -1.9 hypothetical protein compare
Pf6N2E2_4971 -0.7 -4.1 Transcriptional regulator compare
Pf6N2E2_2487 -0.7 -0.8 FIG00956090: hypothetical protein compare
Pf6N2E2_1805 -0.7 -2.3 Multidrug resistance protein B compare
Pf6N2E2_1173 -0.7 -1.7 hypothetical protein compare
Pf6N2E2_3198 -0.7 -1.3 tRNA-guanine transglycosylase (EC 2.4.2.29) compare
Pf6N2E2_3727 -0.7 -0.9 3-hydroxydecanoyl-[ACP] dehydratase (EC 4.2.1.60) compare
Pf6N2E2_2074 -0.7 -1.3 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) compare
Pf6N2E2_3790 -0.7 -2.4 hypothetical protein compare
Pf6N2E2_3607 -0.7 -3.5 3'-to-5' exoribonuclease RNase R compare
Pf6N2E2_1043 -0.7 -2.4 Transcriptional regulator, IclR family compare
Pf6N2E2_1774 -0.6 -1.1 DNA-binding response regulator, LuxR family, near polyamine transporter compare
Pf6N2E2_3261 -0.6 -1.9 hypothetical protein compare
Pf6N2E2_2477 -0.6 -1.5 ABC transporter ATP-binding protein YvcR compare
Pf6N2E2_4427 -0.6 -1.2 FIG00954215: hypothetical protein compare
Pf6N2E2_1056 -0.6 -2.6 Quinone oxidoreductase (EC 1.6.5.5) compare
Pf6N2E2_4562 -0.6 -2.2 L-cystine uptake protein TcyP compare
Pf6N2E2_4453 -0.6 -5.4 Polyphosphate kinase (EC 2.7.4.1) compare
Pf6N2E2_5746 -0.6 -1.7 Cobalamin synthase compare
Pf6N2E2_3240 -0.6 -1.0 Methylated-DNA--protein-cysteine methyltransferase (EC 2.1.1.63) compare
Pf6N2E2_2706 -0.6 -2.0 Allophanate hydrolase 2 subunit 2 (EC 3.5.1.54) compare
Pf6N2E2_81 -0.6 -2.1 hypothetical protein compare
Pf6N2E2_6093 -0.6 -1.9 hypothetical protein compare
Pf6N2E2_1512 -0.6 -2.4 Thiamin biosynthesis lipoprotein ApbE compare
Pf6N2E2_2396 -0.6 -2.5 Sensor histidine kinase compare
Pf6N2E2_687 -0.6 -1.4 4-oxalocrotonate tautomerase (EC 5.3.2.-) compare
Pf6N2E2_63 -0.6 -2.6 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) compare
Pf6N2E2_2038 -0.6 -2.8 Transcriptional regulator, TetR family compare
Pf6N2E2_622 -0.6 -2.3 BatA (Bacteroides aerotolerance operon) compare
Pf6N2E2_350 -0.6 -1.5 Gfa-like protein compare
Pf6N2E2_5841 -0.6 -0.9 GlcG protein compare
Pf6N2E2_5605 -0.6 -2.0 FxsA protein compare
Pf6N2E2_3015 -0.6 -2.3 hypothetical protein compare
Pf6N2E2_5103 -0.6 -1.0 Glutamate 5-kinase (EC 2.7.2.11) / RNA-binding C-terminal domain PUA compare
Pf6N2E2_1933 -0.6 -2.4 TcuR: regulates tcuABC genes used in utilization of tricarballylate compare
Pf6N2E2_2940 -0.6 -2.7 OmpA family protein compare
Pf6N2E2_865 -0.6 -1.3 Fumarylacetoacetate hydrolase family protein compare
Pf6N2E2_4928 -0.6 -0.7 Permeases of the major facilitator superfamily compare
Pf6N2E2_5720 -0.6 -4.0 BarA sensory histidine kinase (= VarS = GacS) compare
Pf6N2E2_624 -0.6 -2.9 hypothetical protein PA3071 compare
Pf6N2E2_3695 -0.6 -2.3 Helix-turn-helix motif compare
Pf6N2E2_5593 -0.6 -1.6 Leucyl-tRNA synthetase compare
Pf6N2E2_5722 -0.6 -2.4 23S rRNA (Uracil-5-) -methyltransferase RumA (EC 2.1.1.-) ## LSU rRNA m(5)U1939 compare
Pf6N2E2_2106 -0.6 -1.4 hypothetical protein compare
Pf6N2E2_1113 -0.6 -1.7 Transcriptional regulator, TetR family compare
Pf6N2E2_4480 -0.6 -4.4 Xaa-Pro aminopeptidase (EC 3.4.11.9) compare
Pf6N2E2_1720 -0.6 -1.9 hypothetical protein compare
Pf6N2E2_1812 -0.6 -1.7 peptide ABC transporter, ATP-binding protein compare
Pf6N2E2_4721 -0.6 -1.8 Sarcosine oxidase gamma subunit (EC 1.5.3.1) compare
Pf6N2E2_3106 -0.6 -2.2 hypothetical protein compare
Pf6N2E2_2750 -0.6 -3.3 Putative permease PerM (= YfgO) compare
Pf6N2E2_1792 -0.6 -1.5 Hydroxypyruvate isomerase (EC 5.3.1.22) compare
Pf6N2E2_5961 -0.6 -3.1 Transcriptional regulator, TetR family compare
Pf6N2E2_525 -0.6 -2.6 C4-type zinc finger protein, DksA/TraR family compare
Pf6N2E2_1753 -0.6 -2.3 FIG00643128: hypothetical protein compare
Pf6N2E2_5990 -0.6 -1.4 Translation initiation factor 2 (IF-2; GTPase) compare
Pf6N2E2_3603 -0.6 -3.2 FIG003573: hypothetical protein compare
Pf6N2E2_734 -0.6 -1.8 Molybdenum cofactor biosynthesis protein MoaA compare
Pf6N2E2_4071 -0.6 -1.9 Phosphate transport system regulatory protein PhoU compare
Pf6N2E2_127 -0.6 -1.3 AttE component of AttEFGH ABC transport system compare
Pf6N2E2_5738 -0.6 -3.5 Cobyrinic acid A,C-diamide synthase compare
Pf6N2E2_4916 -0.6 -1.7 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) compare
Pf6N2E2_5555 -0.6 -0.9 Cold shock protein CspA compare
Pf6N2E2_2544 -0.6 -3.1 Deblocking aminopeptidase (EC 3.4.11.-) @ Cyanophycinase 2 (EC 3.4.15.6) compare
Pf6N2E2_5331 -0.6 -2.8 ATPase, AFG1 family compare
Pf6N2E2_712 -0.5 -2.2 hypothetical protein compare
Pf6N2E2_4751 -0.5 -1.9 response regulator compare
Pf6N2E2_5386 -0.5 -2.7 Alginate biosynthesis protein Alg44 compare
Pf6N2E2_5242 -0.5 -1.2 Malate:quinone oxidoreductase (EC 1.1.5.4) compare
Pf6N2E2_2870 -0.5 -2.1 Ribonuclease BN (EC 3.1.-.-) compare
Pf6N2E2_1966 -0.5 -1.1 SAM-dependent methyltransferases compare
Pf6N2E2_4975 -0.5 -2.3 Histone acetyltransferase HPA2 and related acetyltransferases compare
Pf6N2E2_5088 -0.5 -1.2 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
Pf6N2E2_1803 -0.5 -1.7 Polysaccharide deacetylase compare
Pf6N2E2_2285 -0.5 -1.0 FIG00954079: hypothetical protein compare
Pf6N2E2_2934 -0.5 -1.5 lipoprotein, putative compare
Pf6N2E2_3260 -0.5 -2.4 Uncharacterized ABC transporter, ATP-binding protein YrbF compare
Pf6N2E2_613 -0.5 -0.9 lipoprotein, putative compare
Pf6N2E2_5243 -0.5 -0.9 hypothetical protein compare
Pf6N2E2_3213 -0.5 -2.5 DNA-binding response regulator, AraC family compare
Pf6N2E2_4152 -0.5 -3.1 alginate biosynthesis transcriptional regulatory protein AlgB compare
Pf6N2E2_2296 -0.5 -1.6 FIG00954767: hypothetical protein compare
Pf6N2E2_3725 -0.5 -1.4 FIG085779: Lipoprotein compare
Pf6N2E2_4300 -0.5 -2.0 Uncharacterized protein similar to VCA0109 compare
Pf6N2E2_2467 -0.5 -1.0 5'-nucleotidase (EC 3.1.3.5) compare
Pf6N2E2_2447 -0.5 -3.5 Probable protease htpX homolog (EC 3.4.24.-) compare
Pf6N2E2_1917 -0.5 -1.1 hypothetical protein compare
Pf6N2E2_2962 -0.5 -1.9 ABC transporter for L-Lysine, ATPase component (from data) compare
Pf6N2E2_2071 -0.5 -1.6 hypothetical protein compare
Pf6N2E2_2103 -0.5 -1.8 hypothetical protein compare
Pf6N2E2_49 -0.5 -2.1 FIG00967200: hypothetical protein compare
Pf6N2E2_841 -0.5 -1.5 hypothetical protein compare
Pf6N2E2_2357 -0.5 -1.4 Invasion protein iagA compare
Pf6N2E2_2309 -0.5 -1.3 hypothetical protein compare
Pf6N2E2_1283 -0.5 -1.5 Ferric siderophore transport system, periplasmic binding protein TonB compare
Pf6N2E2_6047 -0.5 -1.1 hypothetical protein compare
Pf6N2E2_5492 -0.5 -2.6 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases compare
Pf6N2E2_5300 -0.5 -4.1 Transcriptional regulator, GntR family domain / Aspartate aminotransferase (EC 2.6.1.1) compare
Pf6N2E2_6022 -0.5 -0.9 StbE replicon stabilization toxin compare
Pf6N2E2_4733 -0.5 -0.9 hypothetical protein compare
Pf6N2E2_3504 -0.5 -3.2 Biosynthetic arginine decarboxylase (EC 4.1.1.19) compare
Pf6N2E2_1617 -0.5 -0.7 COG2199: FOG: GGDEF domain compare
Pf6N2E2_4246 -0.5 -2.4 SAM-dependent methyltransferases compare
Pf6N2E2_2277 -0.5 -1.2 NADPH-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.13) compare
Pf6N2E2_1027 -0.5 -1.4 Cysteine dioxygenase (EC 1.13.11.20) compare
Pf6N2E2_2121 -0.5 -1.3 hypothetical protein compare
Pf6N2E2_2765 -0.5 -2.0 Tricarboxylate transport transcriptional regulator TctD compare
Pf6N2E2_4999 -0.5 -2.6 Membrane-bound lytic murein transglycosylase B precursor (EC 3.2.1.-) compare
Pf6N2E2_2367 -0.5 -1.0 hypothetical protein compare
Pf6N2E2_4204 -0.5 -0.7 rRNA small subunit 7-methylguanosine (m7G) methyltransferase GidB compare
Pf6N2E2_2088 -0.5 -0.5 SOS-response repressor and protease LexA (EC 3.4.21.88) compare
Pf6N2E2_4989 -0.5 -2.0 LrgA-associated membrane protein LrgB compare
Pf6N2E2_5766 -0.5 -1.0 Quaternary ammonium compound-resistance protein SugE compare
Pf6N2E2_621 -0.5 -2.4 TPR domain protein in aerotolerance operon compare
Pf6N2E2_2065 -0.5 -1.5 Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133) compare
Pf6N2E2_799 -0.5 -0.8 hypothetical protein compare


Specific Phenotypes

For 2 genes in this experiment

For stress sodium fluoride in Pseudomonas fluorescens FW300-N2E2

For stress sodium fluoride across organisms