Experiment set7IT019 for Pseudomonas fluorescens FW300-N2E2

Compare to:

LB with sodium fluoride 15 mM

200 most detrimental genes:

  gene name fitness t score description  
Pf6N2E2_4803 +2.2 5.3 Bis(5'-nucleosyl)-tetraphosphatase, symmetrical (EC 3.6.1.41) compare
Pf6N2E2_3843 +2.2 20.7 MFS permease conserved
Pf6N2E2_2510 +1.9 7.5 Lipid carrier : UDP-N-acetylgalactosaminyltransferase (EC 2.4.1.-) / Alpha-1,3-N-acetylgalactosamine transferase PglA (EC 2.4.1.-); Putative glycosyltransferase compare
Pf6N2E2_2513 +1.8 6.1 UDP-glucose dehydrogenase (EC 1.1.1.22) compare
Pf6N2E2_3659 +1.8 9.7 Protein fixF compare
Pf6N2E2_3661 +1.8 10.3 hypothetical protein compare
Pf6N2E2_3791 +1.8 12.8 Glucans biosynthesis glucosyltransferase H (EC 2.4.1.-) compare
Pf6N2E2_3658 +1.8 11.6 Lipid A core - O-antigen ligase and related enzymes compare
Pf6N2E2_3941 +1.7 4.8 Adenosine (5')-pentaphospho-(5'')-adenosine pyrophosphohydrolase (EC 3.6.1.-) compare
Pf6N2E2_2755 +1.7 2.5 Sigma factor RpoE negative regulatory protein RseA compare
Pf6N2E2_3792 +1.7 9.9 Glucans biosynthesis protein G precursor compare
Pf6N2E2_2508 +1.6 5.7 hypothetical protein compare
Pf6N2E2_2507 +1.6 10.2 Undecaprenyl-phosphate N-acetylglucosaminyl 1-phosphate transferase (EC 2.7.8.-) compare
Pf6N2E2_5150 +1.6 7.8 Glucose-6-phosphate isomerase (EC 5.3.1.9) compare
Pf6N2E2_3655 +1.6 13.2 Hypothetical protein FIG015671 in large core OS assembly cluster compare
Pf6N2E2_445 +1.5 8.5 UTP--glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) compare
Pf6N2E2_3096 +1.2 2.4 Periplasmic protein TonB, links inner and outer membranes compare
Pf6N2E2_5986 +1.2 3.8 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
Pf6N2E2_3663 +1.2 7.4 Glycosyl transferase compare
Pf6N2E2_1656 +1.2 2.4 hypothetical protein compare
Pf6N2E2_5014 +1.2 2.8 Apolipoprotein N-acyltransferase (EC 2.3.1.-) / Copper homeostasis protein CutE compare
Pf6N2E2_5771 +1.1 6.9 FKBP-type peptidyl-prolyl cis-trans isomerase FklB (EC 5.2.1.8) compare
Pf6N2E2_2597 +1.1 9.0 Flagellar regulatory protein FleQ compare
Pf6N2E2_3834 +1.1 5.4 Lipoprotein NlpD compare
Pf6N2E2_5345 +1.1 6.7 LppC putative lipoprotein compare
Pf6N2E2_4614 +1.1 3.8 twitching motility protein PilH compare
Pf6N2E2_5133 +1.1 3.3 FIG00953980: hypothetical protein compare
Pf6N2E2_1984 +1.0 3.1 probable exported protein STY4558 compare
Pf6N2E2_241 +1.0 1.7 hypothetical protein compare
Pf6N2E2_2506 +1.0 8.3 nucleotide sugar epimerase/dehydratase WbpM compare
Pf6N2E2_5730 +1.0 3.0 FIG00954480: hypothetical protein compare
Pf6N2E2_1683 +1.0 2.3 Fe2+-dicitrate sensor, membrane component compare
Pf6N2E2_3328 +1.0 2.2 transcriptional regulator compare
Pf6N2E2_2509 +1.0 2.5 UDP-glucose 4-epimerase (EC 5.1.3.2) compare
Pf6N2E2_4454 +0.9 4.6 Exopolyphosphatase (EC 3.6.1.11) compare
Pf6N2E2_3656 +0.9 5.3 Probable transcription regulator Mig-14 compare
Pf6N2E2_4585 +0.9 7.5 Cell division protein FtsX compare
Pf6N2E2_3875 +0.9 2.1 FIG00953324: hypothetical protein compare
Pf6N2E2_5972 +0.9 3.0 hypothetical protein compare
Pf6N2E2_3664 +0.9 5.7 Carbamoyltransferase in large core OS assembly cluster compare
Pf6N2E2_3761 +0.9 8.1 Multimodular transpeptidase-transglycosylase (EC 2.4.1.129) (EC 3.4.-.-) compare
Pf6N2E2_5520 +0.9 4.9 Sensory box histidine kinase compare
Pf6N2E2_434 +0.9 1.8 hypothetical protein compare
Pf6N2E2_3635 +0.9 2.0 FIG00953138: hypothetical protein compare
Pf6N2E2_3844 +0.9 2.2 hypothetical protein compare
Pf6N2E2_3969 +0.9 2.2 Membrane-fusion protein compare
Pf6N2E2_4615 +0.9 2.3 type IV pili signal transduction protein PilI compare
Pf6N2E2_2827 +0.9 1.1 hypothetical protein compare
Pf6N2E2_4973 +0.9 2.6 Inner membrane protein compare
Pf6N2E2_1834 +0.9 2.4 Enoyl-CoA hydratase (EC 4.2.1.17) compare
Pf6N2E2_5794 +0.9 2.5 Ribosomal large subunit pseudouridine synthase A (EC 4.2.1.70) compare
Pf6N2E2_802 +0.8 5.7 Threonine dehydratase biosynthetic (EC 4.3.1.19) compare
Pf6N2E2_4943 +0.8 2.1 PspA/IM30 family protein compare
Pf6N2E2_5160 +0.8 2.1 C4-type zinc finger protein, DksA/TraR family compare
Pf6N2E2_4541 +0.8 1.6 hypothetical protein compare
Pf6N2E2_4579 +0.8 2.0 Ribosomal RNA small subunit methyltransferase D (EC 2.1.1.-) compare
Pf6N2E2_2754 +0.8 4.0 Sigma factor RpoE negative regulatory protein RseB precursor compare
Pf6N2E2_5869 +0.8 2.4 Helicase subunit of the DNA excision repair complex compare
Pf6N2E2_4365 +0.8 5.3 Ribonuclease PH (EC 2.7.7.56) compare
Pf6N2E2_1009 +0.8 1.7 Inositol transport system permease protein compare
Pf6N2E2_1092 +0.8 2.6 Probable vanillate O-demethylase oxygenase subunit oxidoreductase protein (EC 1.14.13.-) compare
Pf6N2E2_3835 +0.8 3.8 Carboxyl-terminal protease (EC 3.4.21.102) compare
Pf6N2E2_1743 +0.8 2.7 Putrescine transport ATP-binding protein PotA (TC 3.A.1.11.1) compare
Pf6N2E2_2582 +0.8 3.1 Flagellar motor switch protein FliN compare
Pf6N2E2_4543 +0.8 3.3 hypothetical protein compare
Pf6N2E2_6058 +0.8 4.3 FIG139976: hypothetical protein compare
Pf6N2E2_3040 +0.8 3.8 5-nucleotidase SurE (EC 3.1.3.5) compare
Pf6N2E2_1288 +0.8 2.1 Protein containing transglutaminase-like domain, putative cysteine protease compare
Pf6N2E2_3516 +0.8 2.4 Probable transmembrane protein compare
Pf6N2E2_2753 +0.8 2.1 HtrA protease/chaperone protein compare
Pf6N2E2_4162 +0.8 1.9 DNA polymerase I (EC 2.7.7.7) compare
Pf6N2E2_1103 +0.7 2.4 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase (EC 4.1.2.n4) compare
Pf6N2E2_2752 +0.7 4.6 Exported zinc metalloprotease YfgC precursor compare
Pf6N2E2_2124 +0.7 1.7 Mg(2+) transport ATPase protein C compare
Pf6N2E2_4678 +0.7 0.9 hypothetical protein compare
Pf6N2E2_3338 +0.7 1.1 1-phosphofructokinase (EC 2.7.1.56) compare
Pf6N2E2_5219 +0.7 5.3 FIG140336: TPR domain protein compare
Pf6N2E2_804 +0.7 4.0 Fructokinase (EC 2.7.1.4) compare
Pf6N2E2_961 +0.7 2.3 FIG00954712: hypothetical protein compare
Pf6N2E2_953 +0.7 1.2 FIG00958851: hypothetical protein compare
Pf6N2E2_919 +0.7 1.6 FIG00954373: hypothetical protein compare
Pf6N2E2_6164 +0.7 1.1 tRNA-Val-TAC compare
Pf6N2E2_3179 +0.7 1.1 FIG021952: putative membrane protein compare
Pf6N2E2_2247 +0.7 2.4 Transcriptional regulator, AraC family compare
Pf6N2E2_5312 +0.7 1.6 FIG00964214: hypothetical protein compare
Pf6N2E2_4120 +0.7 5.4 Trk system potassium uptake protein TrkA compare
Pf6N2E2_3617 +0.7 3.4 N-acetylmuramoyl-L-alanine amidase (EC 3.5.1.28) compare
Pf6N2E2_136 +0.7 2.7 Glycolate dehydrogenase (EC 1.1.99.14), FAD-binding subunit GlcE compare
Pf6N2E2_1329 +0.7 3.0 Phenylacetaldehyde dehydrogenase (EC 1.2.1.39) compare
Pf6N2E2_4570 +0.7 2.5 Cation/multidrug efflux pump compare
Pf6N2E2_2984 +0.7 1.5 LysR family transcriptional regulator PA3398 compare
Pf6N2E2_2592 +0.7 3.8 Flagellar motor switch protein FliG compare
Pf6N2E2_648 +0.7 1.5 General secretion pathway protein K compare
Pf6N2E2_4556 +0.7 3.4 FIG00953078: hypothetical protein compare
Pf6N2E2_3720 +0.7 2.6 FIG027190: Putative transmembrane protein compare
Pf6N2E2_1391 +0.6 1.8 DNA-binding response regulator, LuxR family compare
Pf6N2E2_1821 +0.6 0.6 Leucine-responsive regulatory protein, regulator for leucine (or lrp) regulon and high-affinity branched-chain amino acid transport system compare
Pf6N2E2_2561 +0.6 2.0 FIG00955434: hypothetical protein compare
Pf6N2E2_1815 +0.6 2.8 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases compare
Pf6N2E2_180 +0.6 1.8 Transcriptional regulator, MerR family compare
Pf6N2E2_2474 +0.6 4.4 ErfK/YbiS/YcfS/YnhG family protein compare
Pf6N2E2_3039 +0.6 2.9 Protein-L-isoaspartate O-methyltransferase (EC 2.1.1.77) compare
Pf6N2E2_689 +0.6 1.3 FIG00956189: hypothetical protein compare
Pf6N2E2_2824 +0.6 4.7 RND efflux system, inner membrane transporter CmeB compare
Pf6N2E2_3557 +0.6 1.8 Chaperone-modulator protein CbpM compare
Pf6N2E2_698 +0.6 1.9 Heme d1 biosynthesis protein NirH compare
Pf6N2E2_971 +0.6 1.9 hypothetical protein compare
Pf6N2E2_2903 +0.6 2.2 Heme oxygenase HemO, associated with heme uptake compare
Pf6N2E2_2585 +0.6 3.9 Flagellar hook-length control protein FliK compare
Pf6N2E2_2634 +0.6 4.1 Potassium uptake protein TrkH compare
Pf6N2E2_4827 +0.6 2.0 Lipoate-protein ligase A compare
Pf6N2E2_3475 +0.6 1.5 hypothetical protein compare
Pf6N2E2_2625 +0.6 2.9 Flagellar P-ring protein FlgI compare
Pf6N2E2_2788 +0.6 1.6 Transcriptional regulator, AsnC family compare
Pf6N2E2_1032 +0.6 1.0 Alkanesulfonates ABC transporter ATP-binding protein / Sulfonate ABC transporter, ATP-binding subunit SsuB compare
Pf6N2E2_2413 +0.6 1.4 FIG074102: hypothetical protein compare
Pf6N2E2_1959 +0.6 2.2 D-sorbitol dehydrogenase (EC 1.1.1.14) (from data) compare
Pf6N2E2_5494 +0.6 2.1 Pyruvate kinase (EC 2.7.1.40) compare
Pf6N2E2_1667 +0.6 1.7 Fumarylacetoacetate hydrolase family protein compare
Pf6N2E2_1031 +0.6 2.1 Alkanesulfonates transport system permease protein compare
Pf6N2E2_1339 +0.6 1.1 Acetylornithine deacetylase (EC 3.5.1.16) compare
Pf6N2E2_3825 +0.6 2.2 Nitrogen regulation protein NtrB (EC 2.7.13.3) compare
Pf6N2E2_5190 +0.6 3.9 Carbonic anhydrase (EC 4.2.1.1) compare
Pf6N2E2_1147 +0.6 1.5 Enoyl-CoA hydratase [valine degradation] (EC 4.2.1.17) compare
Pf6N2E2_3237 +0.6 1.5 hypothetical protein compare
Pf6N2E2_2323 +0.6 1.1 Fumarate and nitrate reduction regulatory protein compare
Pf6N2E2_5340 +0.5 2.3 Stringent starvation protein A compare
Pf6N2E2_2363 +0.5 1.8 Type III secretion inner membrane protein (YscT,HrcT,SpaR,EscT,EpaR1,homologous to flagellar export components) compare
Pf6N2E2_5843 +0.5 1.6 hypothetical protein compare
Pf6N2E2_2219 +0.5 0.9 Cell division trigger factor (EC 5.2.1.8) compare
Pf6N2E2_5001 +0.5 1.3 D-alanyl-D-alanine carboxypeptidase (EC 3.4.16.4) compare
Pf6N2E2_55 +0.5 1.2 Probable hydrolase compare
Pf6N2E2_5536 +0.5 0.8 Holliday junction DNA helicase RuvA compare
Pf6N2E2_5962 +0.5 3.6 Molybdenum cofactor biosynthesis protein MoaA compare
Pf6N2E2_2579 +0.5 3.3 Flagellar biosynthesis protein FliQ compare
Pf6N2E2_6060 +0.5 2.3 Propionate catabolism operon transcriptional regulator of GntR family [predicted] compare
Pf6N2E2_1006 +0.5 2.0 Ribose ABC transport system, periplasmic ribose-binding protein RbsB (TC 3.A.1.2.1) compare
Pf6N2E2_5505 +0.5 1.4 hypothetical protein compare
Pf6N2E2_1759 +0.5 1.4 uncharacterized domain 1 compare
Pf6N2E2_2624 +0.5 3.4 Flagellar protein FlgJ [peptidoglycan hydrolase] (EC 3.2.1.-) compare
Pf6N2E2_5697 +0.5 4.5 Flagellar hook protein FlgE compare
Pf6N2E2_4467 +0.5 1.6 hypothetical protein compare
Pf6N2E2_442 +0.5 2.0 FIG00962345: hypothetical protein compare
Pf6N2E2_4708 +0.5 1.7 hypothetical protein compare
Pf6N2E2_1425 +0.5 2.4 Putrescine ABC transporter putrescine-binding protein PotF (TC 3.A.1.11.2) compare
Pf6N2E2_3285 +0.5 2.3 Rod shape-determining protein MreD compare
Pf6N2E2_4459 +0.5 1.4 Transcriptional regulator, GntR family compare
Pf6N2E2_5768 +0.5 2.2 DNA recombination-dependent growth factor C compare
Pf6N2E2_5342 +0.5 1.6 21 kDa hemolysin precursor compare
Pf6N2E2_891 +0.5 1.8 4-oxalocrotonate tautomerase compare
Pf6N2E2_1438 +0.5 2.0 Methyltransferase (EC 2.1.1.-) compare
Pf6N2E2_6085 +0.5 1.3 Aha1 domain superfamily compare
Pf6N2E2_2422 +0.5 3.3 Molybdopterin biosynthesis protein MoeA compare
Pf6N2E2_6007 +0.5 1.8 Glutathione S-transferase (EC 2.5.1.18) compare
Pf6N2E2_959 +0.5 2.1 putative membrane protein compare
Pf6N2E2_318 +0.5 1.3 Gluconolactonase (EC 3.1.1.17) compare
Pf6N2E2_2823 +0.5 2.0 Multidrug efflux RND membrane fusion protein MexC compare
Pf6N2E2_4478 +0.5 3.0 FIG019278: hypothetical protein compare
Pf6N2E2_1665 +0.5 1.3 hypothetical protein compare
Pf6N2E2_1726 +0.5 2.5 3-methylmercaptopropionyl-CoA ligase (DmdB) compare
Pf6N2E2_5245 +0.5 3.2 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
Pf6N2E2_6087 +0.5 1.3 Short-chain dehydrogenase/reductase SDR compare
Pf6N2E2_1294 +0.5 0.9 Carbon starvation protein A compare
Pf6N2E2_5077 +0.5 2.3 hypothetical protein compare
Pf6N2E2_5712 +0.5 2.1 DNA-3-methyladenine glycosylase (EC 3.2.2.20) compare
Pf6N2E2_2405 +0.5 2.4 Hypothetical protein PvdY @ Siderophore synthetase small component, acetyltransferase compare
Pf6N2E2_4996 +0.5 1.9 LSU m3Psi1915 methyltransferase RlmH compare
Pf6N2E2_642 +0.5 1.2 Sigma factor regulator VreR (cytoplasmic membrane-localized) of trans-envelope signaling system compare
Pf6N2E2_3550 +0.5 1.0 Urea ABC transporter, ATPase protein UrtD compare
Pf6N2E2_5621 +0.5 1.5 DNA-binding response regulator compare
Pf6N2E2_4617 +0.5 4.0 Signal transduction histidine kinase CheA (EC 2.7.3.-) compare
Pf6N2E2_2627 +0.5 2.8 Flagellar basal-body rod protein FlgG compare
Pf6N2E2_1151 +0.5 1.9 UDP-glucose dehydrogenase (EC 1.1.1.22) compare
Pf6N2E2_4331 +0.5 2.0 hypothetical protein compare
Pf6N2E2_3169 +0.5 2.4 Membrane proteins related to metalloendopeptidases compare
Pf6N2E2_1525 +0.5 1.4 Universal stress protein family 5 compare
Pf6N2E2_958 +0.5 1.7 hypothetical protein compare
Pf6N2E2_2593 +0.5 2.3 Flagellar M-ring protein FliF compare
Pf6N2E2_2514 +0.5 1.7 regulator of length of O-antigen component of lipopolysaccharide chains compare
Pf6N2E2_5452 +0.5 1.1 hypothetical protein compare
Pf6N2E2_1624 +0.5 1.8 MbtH-like protein compare
Pf6N2E2_4993 +0.5 1.4 Gamma-glutamyl phosphate reductase (EC 1.2.1.41) compare
Pf6N2E2_4146 +0.5 1.2 Membrane lipoprotein lipid attachment site containing protein USSDB6D compare
Pf6N2E2_4423 +0.5 1.2 FIG00953342: hypothetical protein compare
Pf6N2E2_3033 +0.5 1.1 hypothetical protein compare
Pf6N2E2_2794 +0.5 1.0 putative membrane protein compare
Pf6N2E2_3799 +0.5 1.6 Histidine ammonia-lyase (EC 4.3.1.3) (from data) compare
Pf6N2E2_855 +0.5 1.6 Transcriptional regulator, IclR family compare
Pf6N2E2_488 +0.5 2.7 Gluconolactonase (EC 3.1.1.17) compare
Pf6N2E2_4889 +0.5 2.8 Putative transport protein compare
Pf6N2E2_251 +0.4 1.8 transcriptional regulator compare
Pf6N2E2_465 +0.4 2.5 Probable transmembrane protein compare
Pf6N2E2_4732 +0.4 1.6 hypothetical protein compare
Pf6N2E2_868 +0.4 1.4 Transcriptional regulator, HxlR family compare
Pf6N2E2_2081 +0.4 1.1 putative exported protein compare
Pf6N2E2_6070 +0.4 1.7 FIG137877: Hypothetical protein in pyoverdin gene cluster compare
Pf6N2E2_3008 +0.4 2.3 FIG00954242: hypothetical protein compare
Pf6N2E2_2499 +0.4 1.2 Competence protein ComEA helix-hairpin-helix region precursor compare
Pf6N2E2_4418 +0.4 0.7 Diaminopimelate epimerase (EC 5.1.1.7) compare
Pf6N2E2_2500 +0.4 1.8 Putative membrane protein compare


Specific Phenotypes

For 2 genes in this experiment

For stress sodium fluoride in Pseudomonas fluorescens FW300-N2E2

For stress sodium fluoride across organisms