Experiment set7IT018 for Pseudomonas fluorescens FW300-N2E2

Compare to:

LB with Nickel (II) chloride hexahydrate 0.5 mM

200 most important genes:

  gene name fitness t score description  
Pf6N2E2_4071 -3.3 -5.9 Phosphate transport system regulatory protein PhoU compare
Pf6N2E2_1116 -2.6 -2.1 Inosine-5'-monophosphate dehydrogenase (EC 1.1.1.205) compare
Pf6N2E2_5679 -2.6 -4.2 hypothetical protein compare
Pf6N2E2_3908 -2.3 -7.8 Glutamate--cysteine ligase (EC 6.3.2.2) compare
Pf6N2E2_4797 -2.3 -1.8 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase (EC 2.7.6.3) compare
Pf6N2E2_2285 -2.2 -3.1 FIG00954079: hypothetical protein compare
Pf6N2E2_3282 -2.1 -3.1 FIG005080: Possible exported protein compare
Pf6N2E2_2574 -2.1 -2.5 Flagellar synthesis regulator FleN compare
Pf6N2E2_1824 -2.0 -3.1 hypothetical protein compare
Pf6N2E2_5677 -1.9 -2.0 Carbon storage regulator compare
Pf6N2E2_3261 -1.8 -4.6 hypothetical protein compare
Pf6N2E2_3612 -1.8 -3.4 HflK protein compare
Pf6N2E2_4743 -1.7 -1.7 hypothetical protein compare
Pf6N2E2_5242 -1.7 -2.5 Malate:quinone oxidoreductase (EC 1.1.5.4) compare
Pf6N2E2_4773 -1.7 -1.6 Coenzyme PQQ synthesis protein D compare
Pf6N2E2_5252 -1.7 -3.0 FIG00956396: hypothetical protein compare
Pf6N2E2_4638 -1.6 -3.8 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) compare
Pf6N2E2_43 -1.6 -5.6 Histidine permease YuiF compare
Pf6N2E2_3574 -1.5 -10.0 Mannose-6-phosphate isomerase (EC 5.3.1.8) conserved
Pf6N2E2_5261 -1.5 -1.6 FIG00956983: hypothetical protein compare
Pf6N2E2_4075 -1.5 -5.2 Phosphate ABC transporter, periplasmic phosphate-binding protein PstS (TC 3.A.1.7.1) compare
Pf6N2E2_88 -1.4 -2.8 hypothetical protein compare
Pf6N2E2_3537 -1.3 -4.6 Cobalt-precorrin-6x reductase (EC 1.3.1.54) compare
Pf6N2E2_58 -1.3 -2.0 tRNA-dihydrouridine synthase C (EC 1.-.-.-) compare
Pf6N2E2_4204 -1.3 -1.5 rRNA small subunit 7-methylguanosine (m7G) methyltransferase GidB compare
Pf6N2E2_3534 -1.3 -2.8 Cobalamin biosynthesis protein CobG compare
Pf6N2E2_2277 -1.3 -2.5 NADPH-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.13) compare
Pf6N2E2_4072 -1.3 -4.4 Phosphate transport ATP-binding protein PstB (TC 3.A.1.7.1) compare
Pf6N2E2_5316 -1.2 -2.3 Periplasmic thiol:disulfide oxidoreductase DsbB, required for DsbA reoxidation compare
Pf6N2E2_4678 -1.2 -1.0 hypothetical protein compare
Pf6N2E2_4611 -1.2 -2.7 Ferric siderophore transport system, periplasmic binding protein TonB compare
Pf6N2E2_5742 -1.2 -5.4 Cobyric acid synthase (EC 6.3.5.10) compare
Pf6N2E2_4640 -1.2 -2.1 hypothetical protein compare
Pf6N2E2_5340 -1.2 -2.7 Stringent starvation protein A compare
Pf6N2E2_3349 -1.2 -2.4 Polyribonucleotide nucleotidyltransferase (EC 2.7.7.8) compare
Pf6N2E2_2059 -1.1 -2.6 ChlI component of cobalt chelatase involved in B12 biosynthesis compare
Pf6N2E2_302 -1.1 -4.4 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) compare
Pf6N2E2_4993 -1.1 -2.6 Gamma-glutamyl phosphate reductase (EC 1.2.1.41) compare
Pf6N2E2_5646 -1.1 -1.8 PROBABLE MEMBRANE PROTEIN compare
Pf6N2E2_4416 -1.1 -2.1 Tyrosine recombinase XerC compare
Pf6N2E2_3198 -1.1 -1.8 tRNA-guanine transglycosylase (EC 2.4.2.29) compare
Pf6N2E2_4369 -1.1 -1.9 Exodeoxyribonuclease III (EC 3.1.11.2) compare
Pf6N2E2_5155 -1.0 -2.6 Poly(A) polymerase (EC 2.7.7.19) compare
Pf6N2E2_1450 -1.0 -2.2 FIG00960438: hypothetical protein compare
Pf6N2E2_1056 -1.0 -3.0 Quinone oxidoreductase (EC 1.6.5.5) compare
Pf6N2E2_5006 -1.0 -5.5 Muramoyltetrapeptide carboxypeptidase (EC 3.4.17.13) compare
Pf6N2E2_2708 -1.0 -3.9 Lactam utilization protein LamB compare
Pf6N2E2_1095 -1.0 -2.1 Opine oxidase subunit C compare
Pf6N2E2_4187 -1.0 -2.4 Lipid A biosynthesis lauroyl acyltransferase (EC 2.3.1.-) compare
Pf6N2E2_5705 -1.0 -2.3 Sensor protein PhoQ (EC 2.7.13.3) compare
Pf6N2E2_4153 -1.0 -1.0 Sensory box histidine kinase compare
Pf6N2E2_2065 -0.9 -2.7 Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133) compare
Pf6N2E2_3255 -0.9 -3.1 YrbA protein compare
Pf6N2E2_5103 -0.9 -1.3 Glutamate 5-kinase (EC 2.7.2.11) / RNA-binding C-terminal domain PUA compare
Pf6N2E2_3529 -0.9 -2.0 Toxin A compare
Pf6N2E2_2068 -0.9 -4.3 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13) compare
Pf6N2E2_4624 -0.9 -0.9 Phosphoribosyl-dephospho-CoA transferase (EC 2.7.7.-) compare
Pf6N2E2_4969 -0.9 -1.2 hypothetical protein compare
Pf6N2E2_5640 -0.9 -2.1 FIG00955597: hypothetical protein compare
Pf6N2E2_2325 -0.9 -4.0 Recombination protein RecR compare
Pf6N2E2_5406 -0.9 -2.2 FIG00958224: hypothetical protein compare
Pf6N2E2_2080 -0.9 -1.3 hypothetical protein compare
Pf6N2E2_5425 -0.9 -0.6 hypothetical protein compare
Pf6N2E2_2646 -0.9 -1.4 FIG00953416: hypothetical protein compare
Pf6N2E2_3607 -0.9 -4.9 3'-to-5' exoribonuclease RNase R compare
Pf6N2E2_3351 -0.9 -3.3 tRNA pseudouridine synthase B (EC 4.2.1.70) compare
Pf6N2E2_3841 -0.9 -3.8 Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) compare
Pf6N2E2_1694 -0.9 -1.3 FMN reductase (EC 1.5.1.29) compare
Pf6N2E2_5573 -0.9 -3.4 Glycerol-3-phosphate regulon repressor, DeoR family compare
Pf6N2E2_3763 -0.9 -2.1 hypothetical protein compare
Pf6N2E2_4612 -0.9 -3.1 Glutathione synthetase (EC 6.3.2.3) compare
Pf6N2E2_3533 -0.9 -3.3 Cobalt-precorrin-8x methylmutase (EC 5.4.1.2) compare
Pf6N2E2_623 -0.9 -1.0 FIG00954674: hypothetical protein compare
Pf6N2E2_4661 -0.8 -2.2 KluA regulatory protein compare
Pf6N2E2_295 -0.8 -2.8 Leucyl/phenylalanyl-tRNA--protein transferase (EC 2.3.2.6) compare
Pf6N2E2_2074 -0.8 -1.3 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) compare
Pf6N2E2_4963 -0.8 -1.7 Homoserine dehydrogenase (EC 1.1.1.3) compare
Pf6N2E2_5430 -0.8 -4.7 Transglycosylase, Slt family compare
Pf6N2E2_5841 -0.8 -1.2 GlcG protein compare
Pf6N2E2_1636 -0.8 -4.3 Ferrichrome-iron receptor compare
Pf6N2E2_754 -0.8 -1.6 Histone acetyltransferase HPA2 and related acetyltransferases compare
Pf6N2E2_2755 -0.8 -1.2 Sigma factor RpoE negative regulatory protein RseA compare
Pf6N2E2_3876 -0.8 -2.1 Agmatine deiminase (EC 3.5.3.12) compare
Pf6N2E2_4392 -0.8 -2.1 Translation initiation inhibitor compare
Pf6N2E2_1635 -0.8 -2.8 ABC-type cobalamin/Fe3+-siderophores transport systems ATPase components compare
Pf6N2E2_5749 -0.8 -2.3 hypothetical protein compare
Pf6N2E2_4352 -0.8 -2.1 ATP-dependent DNA helicase RecG (EC 3.6.1.-) compare
Pf6N2E2_4733 -0.8 -1.4 hypothetical protein compare
Pf6N2E2_5739 -0.8 -1.2 Cobalamin biosynthesis protein BluB @ 5,6-dimethylbenzimidazole synthase, flavin destructase family compare
Pf6N2E2_1153 -0.8 -3.1 small molecule metabolism; degradation; fatty acid compare
Pf6N2E2_2480 -0.8 -1.5 FIG00957636: hypothetical protein compare
Pf6N2E2_5536 -0.8 -0.8 Holliday junction DNA helicase RuvA compare
Pf6N2E2_620 -0.8 -3.7 BatD compare
Pf6N2E2_440 -0.8 -2.2 FIG00954920: hypothetical protein compare
Pf6N2E2_5945 -0.8 -3.3 Similar to phosphoglycolate phosphatase, clustered with ribosomal large subunit pseudouridine synthase C compare
Pf6N2E2_3021 -0.8 -1.1 hypothetical protein compare
Pf6N2E2_4205 -0.8 -2.5 Chromosome (plasmid) partitioning protein ParA compare
Pf6N2E2_600 -0.8 -2.1 Diadenosine tetraphosphatase and related serine/threonine protein phosphatases compare
Pf6N2E2_2536 -0.8 -1.7 Fumarate hydratase class II (EC 4.2.1.2) compare
Pf6N2E2_1774 -0.7 -1.5 DNA-binding response regulator, LuxR family, near polyamine transporter compare
Pf6N2E2_868 -0.7 -1.9 Transcriptional regulator, HxlR family compare
Pf6N2E2_3948 -0.7 -4.5 Lead, cadmium, zinc and mercury transporting ATPase (EC 3.6.3.3) (EC 3.6.3.5); Copper-translocating P-type ATPase (EC 3.6.3.4) compare
Pf6N2E2_3532 -0.7 -3.6 Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130) compare
Pf6N2E2_288 -0.7 -1.4 Isocitrate dehydrogenase [NADP] (EC 1.1.1.42); Monomeric isocitrate dehydrogenase [NADP] (EC 1.1.1.42) compare
Pf6N2E2_5081 -0.7 -2.6 hypothetical protein compare
Pf6N2E2_285 -0.7 -2.5 FIG002903: a protein of unknown function perhaps involved in purine metabolism compare
Pf6N2E2_1195 -0.7 -2.5 hypothetical protein compare
Pf6N2E2_1625 -0.7 -2.5 Ferric reductase (1.6.99.14) compare
Pf6N2E2_1213 -0.7 -2.1 hypothetical protein compare
Pf6N2E2_617 -0.7 -2.3 Probable glutathione S-transferase compare
Pf6N2E2_4987 -0.7 -0.9 MaoC-like domain protein compare
Pf6N2E2_3260 -0.7 -2.9 Uncharacterized ABC transporter, ATP-binding protein YrbF compare
Pf6N2E2_2218 -0.7 -2.3 ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92) compare
Pf6N2E2_2640 -0.7 -1.6 Permease of the drug/metabolite transporter (DMT) superfamily compare
Pf6N2E2_2985 -0.7 -2.1 Diacylglycerol kinase (EC 2.7.1.107) compare
Pf6N2E2_5745 -0.7 -3.6 Alpha-ribazole-5'-phosphate phosphatase (EC 3.1.3.73) compare
Pf6N2E2_2300 -0.7 -2.4 LSU rRNA 2'-O-methyl-C2498 methyltransferase RlmM compare
Pf6N2E2_4999 -0.7 -3.7 Membrane-bound lytic murein transglycosylase B precursor (EC 3.2.1.-) compare
Pf6N2E2_420 -0.7 -1.0 Chemotaxis regulator - transmits chemoreceptor signals to flagelllar motor components CheY compare
Pf6N2E2_612 -0.7 -2.5 Ketoglutarate semialdehyde dehydrogenase (EC 1.2.1.26) (from data) compare
Pf6N2E2_3696 -0.7 -0.9 hypothetical protein compare
Pf6N2E2_1633 -0.7 -2.5 Iron(III) dicitrate transport system permease protein FecD (TC 3.A.1.14.1) compare
Pf6N2E2_5499 -0.7 -0.9 hypothetical protein compare
Pf6N2E2_3531 -0.7 -2.8 Cobalamin biosynthesis protein CbiG / Cobalt-precorrin-3b C17-methyltransferase compare
Pf6N2E2_3293 -0.7 -1.3 4-carboxymuconolactone decarboxylase (EC 4.1.1.44) compare
Pf6N2E2_2940 -0.7 -3.3 OmpA family protein compare
Pf6N2E2_5088 -0.7 -1.3 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
Pf6N2E2_525 -0.6 -3.0 C4-type zinc finger protein, DksA/TraR family compare
Pf6N2E2_1353 -0.6 -2.9 FIG002577: Putative lipoprotein precursor compare
Pf6N2E2_3516 -0.6 -1.2 Probable transmembrane protein compare
Pf6N2E2_4453 -0.6 -5.2 Polyphosphate kinase (EC 2.7.4.1) compare
Pf6N2E2_1312 -0.6 -1.8 4-hydroxyphenylacetate symporter, major facilitator superfamily (MFS) compare
Pf6N2E2_3460 -0.6 -1.1 Exodeoxyribonuclease V beta chain (EC 3.1.11.5) compare
Pf6N2E2_5605 -0.6 -1.6 FxsA protein compare
Pf6N2E2_870 -0.6 -2.1 DNA-binding response regulator compare
Pf6N2E2_1545 -0.6 -2.2 N-carbamoylputrescine amidase (EC 3.5.1.53) compare
Pf6N2E2_2371 -0.6 -1.0 Type III secretion outermembrane contact sensing protein (YopN,Yop4b,LcrE) compare
Pf6N2E2_4367 -0.6 -1.4 hypothetical protein compare
Pf6N2E2_2073 -0.6 -3.5 Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2) compare
Pf6N2E2_2264 -0.6 -2.0 NADPH dependent preQ0 reductase (EC 1.7.1.13) compare
Pf6N2E2_2064 -0.6 -2.2 Cobalt-precorrin-3b C17-methyltransferase compare
Pf6N2E2_2402 -0.6 -1.5 hypothetical protein compare
Pf6N2E2_2790 -0.6 -1.6 Helix-turn-helix motif compare
Pf6N2E2_204 -0.6 -1.2 hypothetical protein compare
Pf6N2E2_3240 -0.6 -0.9 Methylated-DNA--protein-cysteine methyltransferase (EC 2.1.1.63) compare
Pf6N2E2_5496 -0.6 -1.3 FIG00953991: hypothetical protein compare
Pf6N2E2_2340 -0.6 -2.1 Transcriptional regulator, GntR family compare
Pf6N2E2_2034 -0.6 -2.0 Methyltransferase compare
Pf6N2E2_3106 -0.6 -2.4 hypothetical protein compare
Pf6N2E2_5181 -0.6 -3.8 Paraquat-inducible protein A compare
Pf6N2E2_5555 -0.6 -1.1 Cold shock protein CspA compare
Pf6N2E2_2586 -0.6 -1.0 Hpt domain protein compare
Pf6N2E2_2527 -0.6 -1.8 Oxidoreductase, short chain dehydrogenase/reductase family compare
Pf6N2E2_869 -0.6 -1.3 FMN oxidoreductase compare
Pf6N2E2_5608 -0.6 -2.6 PAP2 superfamily protein compare
Pf6N2E2_3947 -0.6 -0.9 Cd(II)/Pb(II)-responsive transcriptional regulator compare
Pf6N2E2_4691 -0.6 -1.2 hypothetical protein compare
Pf6N2E2_621 -0.6 -2.9 TPR domain protein in aerotolerance operon compare
Pf6N2E2_6063 -0.6 -3.5 2-methylcitrate dehydratase FeS dependent (EC 4.2.1.79) compare
Pf6N2E2_3015 -0.6 -2.3 hypothetical protein compare
Pf6N2E2_1660 -0.6 -1.8 RND efflux system, membrane fusion protein CmeA compare
Pf6N2E2_622 -0.6 -2.2 BatA (Bacteroides aerotolerance operon) compare
Pf6N2E2_4317 -0.6 -1.8 FIG00964469: hypothetical protein compare
Pf6N2E2_2641 -0.6 -3.2 SelT/selW/selH selenoprotein domain compare
Pf6N2E2_605 -0.6 -1.6 FIG002465: BNR repeat protein compare
Pf6N2E2_4418 -0.6 -0.7 Diaminopimelate epimerase (EC 5.1.1.7) compare
Pf6N2E2_3603 -0.6 -3.2 FIG003573: hypothetical protein compare
Pf6N2E2_5766 -0.6 -1.2 Quaternary ammonium compound-resistance protein SugE compare
Pf6N2E2_1803 -0.6 -2.1 Polysaccharide deacetylase compare
Pf6N2E2_5757 -0.6 -1.9 hypothetical protein compare
Pf6N2E2_33 -0.6 -1.3 Diaminopimelate epimerase (EC 5.1.1.7) compare
Pf6N2E2_2251 -0.6 -2.3 NADH-ubiquinone oxidoreductase chain L (EC 1.6.5.3) conserved
Pf6N2E2_1420 -0.6 -2.5 ABC exporter for hemopore HasA, membrane fusion protein (MFP) family component HasE compare
Pf6N2E2_1966 -0.6 -1.0 SAM-dependent methyltransferases compare
Pf6N2E2_4459 -0.6 -1.0 Transcriptional regulator, GntR family compare
Pf6N2E2_624 -0.6 -1.9 hypothetical protein PA3071 compare
Pf6N2E2_453 -0.6 -1.4 LysR family transcriptional regulator STM2281 compare
Pf6N2E2_2967 -0.6 -1.2 Cold shock protein CspA compare
Pf6N2E2_6045 -0.6 -1.0 hypothetical protein compare
Pf6N2E2_2252 -0.6 -2.2 NreA-like protein compare
Pf6N2E2_4974 -0.6 -3.1 DedA protein compare
Pf6N2E2_127 -0.6 -0.9 AttE component of AttEFGH ABC transport system compare
Pf6N2E2_3969 -0.6 -1.0 Membrane-fusion protein compare
Pf6N2E2_2320 -0.6 -1.4 Heavy-metal-associated domain (N-terminus) and membrane-bounded cytochrome biogenesis cycZ-like domain, possible membrane copper tolerance protein compare
Pf6N2E2_264 -0.6 -1.9 Transcriptional regulator, TetR family compare
Pf6N2E2_5668 -0.5 -2.0 Succinylglutamic semialdehyde dehydrogenase (EC 1.2.1.71) compare
Pf6N2E2_89 -0.5 -1.4 hypothetical protein compare
Pf6N2E2_763 -0.5 -1.8 Sigma-54 dependent transcriptional regulator compare
Pf6N2E2_3028 -0.5 -2.5 FIG00959937: hypothetical protein compare
Pf6N2E2_342 -0.5 -0.9 DNA-binding response regulator compare
Pf6N2E2_3611 -0.5 -0.8 HflC protein compare
Pf6N2E2_5494 -0.5 -2.4 Pyruvate kinase (EC 2.7.1.40) compare
Pf6N2E2_5342 -0.5 -1.7 21 kDa hemolysin precursor compare
Pf6N2E2_199 -0.5 -1.8 hypothetical protein compare
Pf6N2E2_28 -0.5 -1.5 4-carboxymuconolactone decarboxylase domain/alkylhydroperoxidase AhpD family core domain protein compare
Pf6N2E2_734 -0.5 -2.0 Molybdenum cofactor biosynthesis protein MoaA compare
Pf6N2E2_5017 -0.5 -2.3 Phosphate starvation-inducible protein PhoH, predicted ATPase compare
Pf6N2E2_4447 -0.5 -4.5 Cytochrome c family protein conserved
Pf6N2E2_1806 -0.5 -1.0 hypothetical protein compare
Pf6N2E2_1289 -0.5 -2.2 Protein containing domains DUF403 compare


Specific Phenotypes

For 2 genes in this experiment

For stress Nickel (II) chloride hexahydrate in Pseudomonas fluorescens FW300-N2E2

For stress Nickel (II) chloride hexahydrate across organisms