Experiment set7IT014 for Pseudomonas fluorescens FW300-N2E2

Compare to:

LB with Tetracycline hydrochloride 0.0004 mg/ml

200 most detrimental genes:

  gene name fitness t score description  
Pf6N2E2_2822 +4.7 30.8 Transcription repressor of multidrug efflux pump acrAB operon, TetR (AcrR) family compare
Pf6N2E2_3663 +4.7 36.2 Glycosyl transferase compare
Pf6N2E2_3659 +4.6 20.7 Protein fixF compare
Pf6N2E2_3661 +3.7 24.8 hypothetical protein compare
Pf6N2E2_2806 +3.6 21.8 Methyltransferase (EC 2.1.1.-) conserved
Pf6N2E2_5647 +3.3 22.7 Transcriptional regulator, TetR family compare
Pf6N2E2_4974 +2.9 18.4 DedA protein compare
Pf6N2E2_3658 +2.6 12.1 Lipid A core - O-antigen ligase and related enzymes compare
Pf6N2E2_3791 +2.1 15.4 Glucans biosynthesis glucosyltransferase H (EC 2.4.1.-) compare
Pf6N2E2_3664 +2.1 11.5 Carbamoyltransferase in large core OS assembly cluster compare
Pf6N2E2_2507 +2.0 10.2 Undecaprenyl-phosphate N-acetylglucosaminyl 1-phosphate transferase (EC 2.7.8.-) compare
Pf6N2E2_4556 +1.9 11.5 FIG00953078: hypothetical protein compare
Pf6N2E2_773 +1.8 12.6 Undecaprenyl-diphosphatase (EC 3.6.1.27) compare
Pf6N2E2_3899 +1.8 12.3 Phosphoenolpyruvate carboxykinase [ATP] (EC 4.1.1.49) compare
Pf6N2E2_2508 +1.7 6.1 hypothetical protein compare
Pf6N2E2_2510 +1.7 6.8 Lipid carrier : UDP-N-acetylgalactosaminyltransferase (EC 2.4.1.-) / Alpha-1,3-N-acetylgalactosamine transferase PglA (EC 2.4.1.-); Putative glycosyltransferase compare
Pf6N2E2_3792 +1.7 10.6 Glucans biosynthesis protein G precursor compare
Pf6N2E2_3655 +1.6 13.8 Hypothetical protein FIG015671 in large core OS assembly cluster compare
Pf6N2E2_2513 +1.6 7.1 UDP-glucose dehydrogenase (EC 1.1.1.22) compare
Pf6N2E2_2509 +1.5 5.6 UDP-glucose 4-epimerase (EC 5.1.3.2) compare
Pf6N2E2_5150 +1.5 8.1 Glucose-6-phosphate isomerase (EC 5.3.1.9) compare
Pf6N2E2_445 +1.5 9.5 UTP--glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) compare
Pf6N2E2_3198 +1.5 4.5 tRNA-guanine transglycosylase (EC 2.4.2.29) compare
Pf6N2E2_5943 +1.4 4.6 hypothetical protein compare
Pf6N2E2_3349 +1.4 3.0 Polyribonucleotide nucleotidyltransferase (EC 2.7.7.8) compare
Pf6N2E2_2526 +1.4 7.5 Similar to phosphoglycolate phosphatase, clustered with ubiquinone biosynthesis SAM-dependent O-methyltransferase compare
Pf6N2E2_3634 +1.3 3.2 Transporter compare
Pf6N2E2_2506 +1.2 9.8 nucleotide sugar epimerase/dehydratase WbpM compare
Pf6N2E2_5525 +1.2 9.4 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases compare
Pf6N2E2_4654 +1.2 5.0 hypothetical protein compare
Pf6N2E2_3285 +1.2 5.4 Rod shape-determining protein MreD compare
Pf6N2E2_4908 +1.1 6.9 UDP-glucose 4-epimerase (EC 5.1.3.2) compare
Pf6N2E2_579 +1.1 2.5 FIG00962753: hypothetical protein compare
Pf6N2E2_5944 +1.0 5.5 Ribosomal large subunit pseudouridine synthase C (EC 4.2.1.70) compare
Pf6N2E2_2518 +1.0 1.1 Cyclohexadienyl dehydrogenase (EC 1.3.1.12)(EC 1.3.1.43) / 5-Enolpyruvylshikimate-3-phosphate synthase (EC 2.5.1.19) compare
Pf6N2E2_2425 +1.0 2.5 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
Pf6N2E2_5574 +1.0 7.7 Glycerol kinase (EC 2.7.1.30) compare
Pf6N2E2_4593 +1.0 4.4 Radical SAM family enzyme, similar to coproporphyrinogen III oxidase, oxygen-independent, clustered with nucleoside-triphosphatase RdgB compare
Pf6N2E2_926 +0.9 5.5 NADH dehydrogenase (EC 1.6.99.3) compare
Pf6N2E2_3480 +0.9 2.1 Transcriptional regulator, ArsR family compare
Pf6N2E2_1424 +0.9 1.5 transcriptional regulator, TetR family compare
Pf6N2E2_4047 +0.9 5.2 Tryptophan synthase alpha chain (EC 4.2.1.20) compare
Pf6N2E2_1676 +0.9 2.5 conserved protein associated with acetyl-CoA C-acyltransferase compare
Pf6N2E2_1683 +0.9 1.6 Fe2+-dicitrate sensor, membrane component compare
Pf6N2E2_5046 +0.8 5.4 ATP-dependent RNA helicase PA3950 compare
Pf6N2E2_3656 +0.8 4.3 Probable transcription regulator Mig-14 compare
Pf6N2E2_4615 +0.8 2.0 type IV pili signal transduction protein PilI compare
Pf6N2E2_5575 +0.8 4.8 Glycerol uptake facilitator protein compare
Pf6N2E2_3727 +0.8 3.0 3-hydroxydecanoyl-[ACP] dehydratase (EC 4.2.1.60) compare
Pf6N2E2_2712 +0.8 4.2 Permeases of the major facilitator superfamily compare
Pf6N2E2_70 +0.8 3.4 tRNA pseudouridine synthase A (EC 4.2.1.70) compare
Pf6N2E2_1288 +0.8 1.7 Protein containing transglutaminase-like domain, putative cysteine protease compare
Pf6N2E2_1656 +0.8 1.4 hypothetical protein compare
Pf6N2E2_3794 +0.8 4.8 Proline iminopeptidase (EC 3.4.11.5) compare
Pf6N2E2_3844 +0.8 2.8 hypothetical protein compare
Pf6N2E2_2674 +0.8 1.0 FIG00953856: hypothetical protein compare
Pf6N2E2_441 +0.8 2.8 FIG00958773: hypothetical protein compare
Pf6N2E2_4305 +0.7 1.2 FIG00959590: hypothetical protein compare
Pf6N2E2_2683 +0.7 4.4 Beta-ketoadipate enol-lactone hydrolase (EC 3.1.1.24) compare
Pf6N2E2_1762 +0.7 2.9 putative lipase compare
Pf6N2E2_1759 +0.7 1.8 uncharacterized domain 1 compare
Pf6N2E2_3872 +0.7 2.7 hypothetical protein compare
Pf6N2E2_2588 +0.7 2.0 Anti-sigma F factor antagonist (spoIIAA-2); Anti-sigma B factor antagonist RsbV compare
Pf6N2E2_5237 +0.7 1.7 Hypoxanthine-guanine phosphoribosyltransferase (EC 2.4.2.8) compare
Pf6N2E2_3761 +0.7 6.2 Multimodular transpeptidase-transglycosylase (EC 2.4.1.129) (EC 3.4.-.-) compare
Pf6N2E2_1959 +0.7 2.3 D-sorbitol dehydrogenase (EC 1.1.1.14) (from data) compare
Pf6N2E2_2821 +0.7 3.0 hypothetical protein compare
Pf6N2E2_1294 +0.7 1.8 Carbon starvation protein A compare
Pf6N2E2_2375 +0.7 1.7 Response regulator NasT compare
Pf6N2E2_648 +0.7 1.6 General secretion pathway protein K compare
Pf6N2E2_5226 +0.7 1.5 FIG00955589: hypothetical protein compare
Pf6N2E2_4659 +0.7 3.0 Lipoprotein, putative compare
Pf6N2E2_5345 +0.7 4.1 LppC putative lipoprotein compare
Pf6N2E2_2999 +0.7 2.1 probable tail fiber assembly protein compare
Pf6N2E2_4165 +0.7 3.3 Zinc ABC transporter, periplasmic-binding protein ZnuA compare
Pf6N2E2_2872 +0.7 4.8 Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) compare
Pf6N2E2_4332 +0.7 3.7 hypothetical protein compare
Pf6N2E2_642 +0.7 1.2 Sigma factor regulator VreR (cytoplasmic membrane-localized) of trans-envelope signaling system compare
Pf6N2E2_2413 +0.7 1.4 FIG074102: hypothetical protein compare
Pf6N2E2_442 +0.6 2.0 FIG00962345: hypothetical protein compare
Pf6N2E2_4167 +0.6 4.1 Zinc ABC transporter, ATP-binding protein ZnuC compare
Pf6N2E2_2645 +0.6 3.0 ATP-dependent DNA helicase RecQ compare
Pf6N2E2_241 +0.6 1.0 hypothetical protein compare
Pf6N2E2_5825 +0.6 2.7 FIG00958237: hypothetical protein compare
Pf6N2E2_5024 +0.6 2.5 Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) compare
Pf6N2E2_4168 +0.6 3.3 Zinc ABC transporter, inner membrane permease protein ZnuB compare
Pf6N2E2_1220 +0.6 1.7 hypothetical protein compare
Pf6N2E2_5018 +0.6 4.0 tRNA-i(6)A37 methylthiotransferase compare
Pf6N2E2_5001 +0.6 1.1 D-alanyl-D-alanine carboxypeptidase (EC 3.4.16.4) compare
Pf6N2E2_3397 +0.6 1.3 Phage protein compare
Pf6N2E2_924 +0.6 1.4 Transcriptional regulator XdhR, TetR family compare
Pf6N2E2_3672 +0.6 3.8 Glutamate-ammonia-ligase adenylyltransferase (EC 2.7.7.42) compare
Pf6N2E2_3328 +0.6 1.0 transcriptional regulator compare
Pf6N2E2_2582 +0.6 2.0 Flagellar motor switch protein FliN compare
Pf6N2E2_4216 +0.6 1.8 Transcriptional regulator of glmS gene, DeoR family compare
Pf6N2E2_6087 +0.6 1.5 Short-chain dehydrogenase/reductase SDR compare
Pf6N2E2_6070 +0.6 2.1 FIG137877: Hypothetical protein in pyoverdin gene cluster compare
Pf6N2E2_1536 +0.6 2.8 Permeases of the major facilitator superfamily compare
Pf6N2E2_3875 +0.6 1.6 FIG00953324: hypothetical protein compare
Pf6N2E2_3505 +0.6 1.2 Translation initiation factor SUI1-related protein compare
Pf6N2E2_1997 +0.6 1.8 FIG00956406: hypothetical protein compare
Pf6N2E2_318 +0.6 2.4 Gluconolactonase (EC 3.1.1.17) compare
Pf6N2E2_1376 +0.6 1.9 probable transmembrane protein compare
Pf6N2E2_3478 +0.6 3.2 Adenosine deaminase (EC 3.5.4.4) compare
Pf6N2E2_2055 +0.5 1.4 StbE replicon stabilization toxin compare
Pf6N2E2_630 +0.5 2.1 Epimerase KguE compare
Pf6N2E2_5712 +0.5 2.0 DNA-3-methyladenine glycosylase (EC 3.2.2.20) compare
Pf6N2E2_504 +0.5 1.3 DNA-binding response regulator compare
Pf6N2E2_2681 +0.5 2.7 3-phosphoglycerate kinase compare
Pf6N2E2_3237 +0.5 1.2 hypothetical protein compare
Pf6N2E2_226 +0.5 1.7 2,3-dihydroxybiphenyl 1,2-dioxygenase compare
Pf6N2E2_3429 +0.5 2.0 hypothetical protein compare
Pf6N2E2_1797 +0.5 1.1 Transcriptional regulator compare
Pf6N2E2_4614 +0.5 1.7 twitching motility protein PilH compare
Pf6N2E2_3638 +0.5 2.2 hypothetical protein compare
Pf6N2E2_2286 +0.5 1.7 FIG00953287: hypothetical protein compare
Pf6N2E2_4531 +0.5 1.2 hypothetical protein compare
Pf6N2E2_1305 +0.5 1.2 Homoprotocatechuate degradative operon repressor compare
Pf6N2E2_1896 +0.5 1.7 hypothetical protein compare
Pf6N2E2_500 +0.5 1.8 Beta-ureidopropionase (EC 3.5.1.6) compare
Pf6N2E2_1168 +0.5 2.2 Transposase compare
Pf6N2E2_2384 +0.5 1.9 CmpX compare
Pf6N2E2_1182 +0.5 1.8 Transcriptional regulator, LysR family compare
Pf6N2E2_4025 +0.5 1.1 hypothetical protein compare
Pf6N2E2_1080 +0.5 2.8 hydrolase, alpha/beta fold family compare
Pf6N2E2_913 +0.5 2.2 FIG00958137: hypothetical protein compare
Pf6N2E2_757 +0.5 2.9 6-phosphogluconate dehydrogenase, decarboxylating (EC 1.1.1.44) compare
Pf6N2E2_804 +0.5 2.5 Fructokinase (EC 2.7.1.4) compare
Pf6N2E2_822 +0.5 3.1 TPR domain protein compare
Pf6N2E2_1009 +0.5 1.3 Inositol transport system permease protein compare
Pf6N2E2_746 +0.5 1.0 FIG00958097: hypothetical protein compare
Pf6N2E2_4996 +0.5 1.7 LSU m3Psi1915 methyltransferase RlmH compare
Pf6N2E2_1966 +0.5 0.9 SAM-dependent methyltransferases compare
Pf6N2E2_2262 +0.5 1.8 Phosphonoacetaldehyde phosphonohydrolase-related protein compare
Pf6N2E2_5236 +0.5 1.6 hypothetical protein compare
Pf6N2E2_5711 +0.5 2.2 tRNA(Cytosine32)-2-thiocytidine synthetase compare
Pf6N2E2_750 +0.5 1.1 Transcriptional regulator, DeoR family compare
Pf6N2E2_5956 +0.5 3.0 FIG004453: protein YceG like compare
Pf6N2E2_4987 +0.5 0.8 MaoC-like domain protein compare
Pf6N2E2_1754 +0.5 1.8 FIG00731982: hypothetical protein compare
Pf6N2E2_163 +0.5 1.8 Ribose ABC transport system, permease protein RbsC (TC 3.A.1.2.1) compare
Pf6N2E2_4990 +0.5 1.1 Uncharacterized protein, similar to the N-terminal domain of Lon protease compare
Pf6N2E2_5520 +0.5 2.6 Sensory box histidine kinase compare
Pf6N2E2_1624 +0.5 1.9 MbtH-like protein compare
Pf6N2E2_3362 +0.5 1.9 hypothetical protein compare
Pf6N2E2_451 +0.5 0.8 transcriptional regulator MvaT, P16 subunit, putative compare
Pf6N2E2_1613 +0.5 1.2 short-chain dehydrogenase/reductase compare
Pf6N2E2_1238 +0.5 1.3 hypothetical protein compare
Pf6N2E2_2633 +0.5 1.4 Nitroreductase family protein compare
Pf6N2E2_3702 +0.5 1.8 FIG00953907: hypothetical protein compare
Pf6N2E2_4467 +0.5 1.5 hypothetical protein compare
Pf6N2E2_333 +0.5 2.8 hypothetical protein compare
Pf6N2E2_893 +0.5 1.1 hypothetical protein compare
Pf6N2E2_3477 +0.5 1.2 2-Oxobutyrate oxidase, putative compare
Pf6N2E2_888 +0.5 1.3 Enoyl-CoA hydratase (EC 4.2.1.17) compare
Pf6N2E2_1049 +0.4 2.0 hypothetical protein compare
Pf6N2E2_2880 +0.4 1.2 FIG00959696: hypothetical protein compare
Pf6N2E2_170 +0.4 1.2 lipoprotein, putative compare
Pf6N2E2_2352 +0.4 1.4 Type III secretion bridge between inner and outermembrane lipoprotein (YscJ,HrcJ,EscJ, PscJ) compare
Pf6N2E2_3911 +0.4 1.9 Taurine transport system permease protein TauC compare
Pf6N2E2_1834 +0.4 1.0 Enoyl-CoA hydratase (EC 4.2.1.17) compare
Pf6N2E2_5153 +0.4 2.1 3-methyl-2-oxobutanoate hydroxymethyltransferase (EC 2.1.2.11) compare
Pf6N2E2_6059 +0.4 1.6 FIG008443: hypothetical protein compare
Pf6N2E2_827 +0.4 1.4 probable dioxygenase compare
Pf6N2E2_237 +0.4 1.4 hypothetical protein compare
Pf6N2E2_2335 +0.4 1.9 Transcriptional regulator, GntR family compare
Pf6N2E2_469 +0.4 1.2 lipoprotein, putative compare
Pf6N2E2_6060 +0.4 1.6 Propionate catabolism operon transcriptional regulator of GntR family [predicted] compare
Pf6N2E2_3539 +0.4 1.6 FIG00955840: hypothetical protein compare
Pf6N2E2_5019 +0.4 3.2 hypothetical protein compare
Pf6N2E2_5632 +0.4 2.0 Aromatic amino acid transport protein AroP compare
Pf6N2E2_133 +0.4 1.4 hypothetical protein compare
Pf6N2E2_1330 +0.4 2.3 Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases compare
Pf6N2E2_4943 +0.4 1.2 PspA/IM30 family protein compare
Pf6N2E2_2903 +0.4 1.8 Heme oxygenase HemO, associated with heme uptake compare
Pf6N2E2_1953 +0.4 2.2 Uncharacterized conserved protein compare
Pf6N2E2_2022 +0.4 2.5 BarA-associated response regulator UvrY (= GacA = SirA) compare
Pf6N2E2_2012 +0.4 0.9 hypothetical protein compare
Pf6N2E2_2794 +0.4 1.0 putative membrane protein compare
Pf6N2E2_3179 +0.4 0.9 FIG021952: putative membrane protein compare
Pf6N2E2_2500 +0.4 1.9 Putative membrane protein compare
Pf6N2E2_4658 +0.4 1.7 FIG00955006: hypothetical protein compare
Pf6N2E2_1506 +0.4 1.1 Putative alkanesulfonate metabolism utilization regulator compare
Pf6N2E2_424 +0.4 2.2 Decarboxylase family protein compare
Pf6N2E2_776 +0.4 2.2 Transcriptional regulator, LysR family compare
Pf6N2E2_2886 +0.4 3.6 Phosphogluconate repressor HexR, RpiR family compare
Pf6N2E2_5994 +0.4 2.2 Superfamily II DNA/RNA helicases, SNF2 family compare
Pf6N2E2_3550 +0.4 0.8 Urea ABC transporter, ATPase protein UrtD compare
Pf6N2E2_4317 +0.4 0.9 FIG00964469: hypothetical protein compare
Pf6N2E2_1339 +0.4 1.0 Acetylornithine deacetylase (EC 3.5.1.16) compare
Pf6N2E2_1021 +0.4 2.0 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) compare
Pf6N2E2_2788 +0.4 0.8 Transcriptional regulator, AsnC family compare
Pf6N2E2_6099 +0.4 0.7 tRNA-Glu-TTC compare
Pf6N2E2_814 +0.4 1.3 hypothetical protein compare
Pf6N2E2_1691 +0.4 1.1 hypothetical protein compare
Pf6N2E2_1987 +0.4 0.5 hypothetical protein compare
Pf6N2E2_2411 +0.4 1.5 Methylcrotonyl-CoA carboxylase biotin-containing subunit (EC 6.4.1.4) compare
Pf6N2E2_2594 +0.4 2.0 Flagellar hook-basal body complex protein FliE compare
Pf6N2E2_1028 +0.4 1.5 Transcriptional regulator, LysR family compare
Pf6N2E2_1670 +0.4 1.5 conserved membrane protein compare


Specific Phenotypes

For 7 genes in this experiment

For stress Tetracycline hydrochloride in Pseudomonas fluorescens FW300-N2E2

For stress Tetracycline hydrochloride across organisms