Experiment set7IT001 for Klebsiella michiganensis M5al

Compare to:

LB with Paraquat dichloride 0.1 mg/ml

200 most detrimental genes:

  gene name fitness t score description  
BWI76_RS13675 +10.7 53.6 TetR family transcriptional regulator compare
BWI76_RS07730 +5.3 19.1 iron-enterobactin transporter membrane protein compare
BWI76_RS07740 +5.2 8.8 Fe2+-enterobactin ABC transporter substrate-binding protein compare
BWI76_RS07725 +5.2 14.5 iron-enterobactin transporter permease compare
BWI76_RS17190 +4.1 15.2 TonB system transport protein TonB compare
BWI76_RS16490 +4.1 17.2 glutaredoxin compare
BWI76_RS05840 +3.8 16.0 glutamate 5-kinase compare
BWI76_RS26095 +3.8 11.4 shikimate kinase compare
BWI76_RS05835 +3.4 18.1 gamma-glutamyl-phosphate reductase compare
BWI76_RS18420 +3.2 17.9 DNA (cytosine-5-)-methyltransferase compare
BWI76_RS07695 +3.1 24.9 TonB-dependent siderophore receptor compare
BWI76_RS24910 +3.0 11.9 rRNA (cytidine-2'-O-)-methyltransferase compare
BWI76_RS20295 +2.8 1.5 dihydroneopterin triphosphate 2'-epimerase compare
BWI76_RS26965 +2.8 1.4 hypothetical protein compare
BWI76_RS01800 +2.7 13.5 glucose-6-phosphate isomerase compare
BWI76_RS12500 +2.7 1.7 dipeptide epimerase compare
BWI76_RS02785 +2.7 14.2 AIG2 family protein compare
BWI76_RS27430 +2.6 5.7 (p)ppGpp synthetase compare
BWI76_RS17330 +2.6 1.7 nitrate reductase subunit beta compare
BWI76_RS24275 +2.6 7.7 biopolymer transport protein ExbD compare
BWI76_RS22120 +2.5 12.9 glutamate--cysteine ligase compare
BWI76_RS06295 +2.5 10.6 S-adenosylmethionine:tRNA ribosyltransferase-isomerase compare
BWI76_RS24280 +2.5 15.7 biopolymer transporter ExbB compare
BWI76_RS01620 +2.4 1.3 hypothetical protein compare
BWI76_RS13720 +2.3 1.6 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase compare
BWI76_RS07325 +2.2 1.7 aminoimidazole riboside kinase compare
BWI76_RS12330 +2.2 2.0 hypothetical protein compare
BWI76_RS09175 +2.1 9.0 DNA-binding transcriptional regulator compare
BWI76_RS18950 +2.1 1.0 imidazole glycerol phosphate synthase cyclase subunit compare
BWI76_RS09105 +2.0 2.3 glutathione ABC transporter permease GsiC compare
BWI76_RS20700 +2.0 10.7 sulfate/thiosulfate transporter subunit conserved
BWI76_RS09295 +2.0 1.5 hypothetical protein compare
BWI76_RS18535 +2.0 1.5 alpha/beta hydrolase compare
BWI76_RS01900 +1.9 1.7 tRNA-dihydrouridine synthase A compare
BWI76_RS01065 +1.8 7.5 ATP-dependent RNA helicase RhlB compare
BWI76_RS16595 +1.8 2.4 hypothetical protein compare
BWI76_RS19850 +1.8 5.5 tRNA-Pro compare
BWI76_RS06465 +1.8 4.3 IclR family transcriptional regulator compare
BWI76_RS02530 +1.8 2.6 tRNA dimethylallyltransferase compare
BWI76_RS25960 +1.7 6.9 NUDIX hydrolase compare
BWI76_RS20155 +1.7 1.6 NADH-quinone oxidoreductase subunit I compare
BWI76_RS07185 +1.7 2.5 hypothetical protein compare
BWI76_RS25920 +1.6 3.2 peptidylprolyl isomerase compare
BWI76_RS24075 +1.6 5.5 glutathione synthase compare
BWI76_RS26435 +1.6 5.3 hypothetical protein compare
BWI76_RS20695 +1.6 7.0 sulfate/thiosulfate transporter permease subunit compare
BWI76_RS25070 +1.6 3.4 hypothetical protein compare
BWI76_RS14525 +1.6 1.7 AraC family transcriptional regulator compare
BWI76_RS25065 +1.6 3.2 polyribonucleotide nucleotidyltransferase compare
BWI76_RS17970 +1.5 3.2 zinc metalloprotease HtpX compare
BWI76_RS20705 +1.5 6.4 thiosulfate transporter subunit compare
BWI76_RS20690 +1.5 7.9 sulfate ABC transporter ATP-binding protein conserved
BWI76_RS08500 +1.5 4.0 cytochrome d ubiquinol oxidase subunit 2 compare
BWI76_RS26565 +1.5 1.3 membrane protein compare
BWI76_RS05235 +1.5 2.1 hypothetical protein compare
BWI76_RS25205 +1.5 4.3 hypothetical protein compare
BWI76_RS08495 +1.5 6.4 cytochrome bd-I ubiquinol oxidase subunit I compare
BWI76_RS07465 +1.4 10.6 TetR family transcriptional regulator compare
BWI76_RS02985 +1.4 0.9 reactive intermediate/imine deaminase compare
BWI76_RS20180 +1.4 1.6 NADH-quinone oxidoreductase subunit C/D compare
BWI76_RS08645 +1.3 1.8 molybdate ABC transporter substrate-binding protein compare
BWI76_RS08020 +1.3 7.3 serine-type D-Ala-D-Ala carboxypeptidase compare
BWI76_RS06540 +1.3 3.3 DNA-binding protein HU-beta compare
BWI76_RS24385 +1.3 6.9 phosphodiesterase compare
BWI76_RS27135 +1.3 6.6 selenocysteine-specific translation factor compare
BWI76_RS25060 +1.3 4.6 lipoprotein NlpI compare
BWI76_RS20650 +1.3 6.9 phosphoenolpyruvate--protein phosphotransferase compare
BWI76_RS02580 +1.3 1.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase compare
BWI76_RS26055 +1.3 7.4 siroheme synthase compare
BWI76_RS20050 +1.2 2.0 hypothetical protein compare
BWI76_RS20740 +1.2 1.0 coproporphyrinogen III oxidase compare
BWI76_RS14505 +1.2 2.3 salicylate synthase Irp9 compare
BWI76_RS23720 +1.2 1.4 calcium-binding protein compare
BWI76_RS06495 +1.2 9.1 cytochrome ubiquinol oxidase subunit II compare
BWI76_RS14835 +1.2 1.3 hypothetical protein compare
BWI76_RS14435 +1.2 1.6 glutamine ABC transporter ATP-binding protein compare
BWI76_RS21390 +1.2 4.1 thiol disulfide reductase thioredoxin compare
BWI76_RS01070 +1.2 4.6 thiol reductase thioredoxin compare
BWI76_RS09625 +1.2 2.0 hypothetical protein compare
BWI76_RS27455 +1.2 2.0 DUF805 domain-containing protein compare
BWI76_RS11765 +1.2 8.1 bifunctional transporter/kinase compare
BWI76_RS13250 +1.2 1.6 cytochrome b561 compare
BWI76_RS02570 +1.1 5.0 transcriptional regulator compare
BWI76_RS27600 +1.1 4.8 tRNA-Sec compare
BWI76_RS00480 +1.1 3.6 hypothetical protein compare
BWI76_RS16025 +1.1 2.2 triphosphoribosyl-dephospho-CoA synthase compare
BWI76_RS15490 +1.1 1.7 mannitol dehydrogenase family protein compare
BWI76_RS21810 +1.1 1.4 universal stress protein compare
BWI76_RS26590 +1.1 2.5 transcriptional regulator compare
BWI76_RS27425 +1.1 1.4 DNA-directed RNA polymerase subunit omega compare
BWI76_RS27140 +1.1 5.2 L-selenocysteinyl-tRNA(Sec) synthase compare
BWI76_RS02575 +1.1 5.1 exoribonuclease R compare
BWI76_RS05015 +1.1 2.1 transcriptional regulator compare
BWI76_RS10615 +1.1 5.3 chorismate mutase compare
BWI76_RS23455 +1.1 1.3 Na(+)-translocating NADH-quinone reductase subunit E compare
BWI76_RS18770 +1.1 1.2 DNA gyrase inhibitor compare
BWI76_RS07470 +1.1 1.9 MBL fold metallo-hydrolase compare
BWI76_RS16340 +1.1 1.4 aryl-phospho-beta-D-glucosidase compare
BWI76_RS08765 +1.1 1.7 8-amino-7-oxononanoate synthase compare
BWI76_RS18565 +1.1 2.2 pemk protein compare
BWI76_RS07940 +1.1 5.7 alkyl hydroperoxide reductase subunit C compare
BWI76_RS26665 +1.1 2.5 DNA-binding response regulator compare
BWI76_RS23520 +1.1 2.0 hypothetical protein compare
BWI76_RS14840 +1.1 2.2 hypothetical protein compare
BWI76_RS07760 +1.0 3.2 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase compare
BWI76_RS08275 +1.0 1.6 LexA regulated protein compare
BWI76_RS12040 +1.0 1.5 hypothetical protein compare
BWI76_RS13560 +1.0 1.2 amino acid ABC transporter substrate-binding subunit compare
BWI76_RS22475 +1.0 2.5 heme ABC transporter ATP-binding protein compare
BWI76_RS14320 +1.0 1.6 hypothetical protein compare
BWI76_RS16745 +1.0 1.4 alpha-acetolactate decarboxylase compare
BWI76_RS06205 +1.0 1.7 recombination-associated protein RdgC compare
BWI76_RS15215 +1.0 1.1 N-acetyltransferase compare
BWI76_RS03295 +1.0 1.1 transposase compare
BWI76_RS20565 +1.0 1.7 hypothetical protein compare
BWI76_RS11920 +1.0 1.6 hypothetical protein compare
BWI76_RS09160 +1.0 5.1 multidrug transporter MdfA compare
BWI76_RS04475 +1.0 1.5 ROK family protein compare
BWI76_RS17250 +1.0 4.1 bifunctional acetaldehyde-CoA/alcohol dehydrogenase compare
BWI76_RS11520 +1.0 1.2 hypothetical protein compare
BWI76_RS14325 +1.0 2.2 maturase compare
BWI76_RS03630 +1.0 3.4 LysR family transcriptional regulator compare
BWI76_RS15385 +1.0 1.6 hypothetical protein compare
BWI76_RS16670 +1.0 0.9 NLPA lipoprotein compare
BWI76_RS13050 +1.0 1.9 transcriptional regulator compare
BWI76_RS17890 +1.0 2.6 PTS mannose transporter subunit EIIAB compare
BWI76_RS06135 +0.9 4.2 MFS transporter compare
BWI76_RS24080 +0.9 1.0 DUF179 domain-containing protein compare
BWI76_RS20915 +0.9 4.7 peroxiredoxin compare
BWI76_RS11815 +0.9 1.4 hypothetical protein compare
BWI76_RS11940 +0.9 3.1 aconitate hydratase 1 compare
BWI76_RS07035 +0.9 1.5 Zn-dependent hydrolase compare
BWI76_RS22135 +0.9 2.5 transport-associated protein compare
BWI76_RS12155 +0.9 2.0 hypothetical protein compare
BWI76_RS14055 +0.9 2.2 LacI family transcriptional regulator compare
BWI76_RS11440 +0.9 1.0 hypothetical protein compare
BWI76_RS16910 +0.9 2.2 2-keto-4-pentenoate hydratase compare
BWI76_RS20930 +0.9 1.6 arsenate reductase (glutaredoxin) compare
BWI76_RS05070 +0.9 1.9 type II secretion system protein GspH compare
BWI76_RS24825 +0.9 1.9 2-hydroxy-3-oxopropionate reductase compare
BWI76_RS20430 +0.9 2.2 penicillin-insensitive murein endopeptidase compare
BWI76_RS18230 +0.9 1.3 trehalose-6-phosphate synthase compare
BWI76_RS07790 +0.9 1.9 plasmid stabilization protein compare
BWI76_RS05005 +0.9 2.4 polynucleotide adenylyltransferase compare
BWI76_RS14110 +0.9 2.9 C-lysozyme inhibitor compare
BWI76_RS00940 +0.9 3.7 transcriptional regulator HdfR compare
BWI76_RS17710 +0.9 2.5 hypothetical protein compare
BWI76_RS10955 +0.9 0.7 hypothetical protein compare
BWI76_RS19750 +0.9 1.2 elongation factor P-like protein YeiP compare
BWI76_RS03610 +0.9 2.1 hypothetical protein compare
BWI76_RS02410 +0.9 1.2 EF-P beta-lysylation protein EpmB compare
BWI76_RS03125 +0.9 1.2 phosphodiesterase compare
BWI76_RS13785 +0.9 1.3 ABC transporter permease compare
BWI76_RS00380 +0.9 5.7 oxygen-independent coproporphyrinogen III oxidase compare
BWI76_RS11870 +0.9 3.6 hypothetical protein compare
BWI76_RS13755 +0.9 1.3 hypothetical protein compare
BWI76_RS08665 +0.9 4.4 6-phosphogluconolactonase compare
BWI76_RS18470 +0.9 1.9 hypothetical protein compare
BWI76_RS21945 +0.9 2.3 LysR family transcriptional regulator compare
BWI76_RS17795 +0.9 2.8 ribonuclease D compare
BWI76_RS01775 +0.9 1.2 hypothetical protein compare
BWI76_RS07045 +0.9 1.9 acyl-CoA synthetase FdrA compare
BWI76_RS04570 +0.9 4.0 RNA polymerase-associated protein RapA compare
BWI76_RS08805 +0.9 2.3 gluconeogenesis factor compare
BWI76_RS12240 +0.8 2.0 terminase small subunit compare
BWI76_RS16785 +0.8 3.6 peptidase M20 compare
BWI76_RS10295 +0.8 2.5 short chain dehydrogenase/reductase family oxidoreductase compare
BWI76_RS16505 +0.8 2.5 MFS transporter compare
BWI76_RS01755 +0.8 3.7 23S rRNA pseudouridine synthase F compare
BWI76_RS07755 +0.8 2.5 isochorismatase compare
BWI76_RS15450 +0.8 2.3 hypothetical protein compare
BWI76_RS25600 +0.8 0.7 tRNA-Thr compare
BWI76_RS06335 +0.8 1.6 nucleoside-specific channel-forming protein Tsx compare
BWI76_RS17230 +0.8 2.6 peptide ABC transporter permease compare
BWI76_RS16880 +0.8 3.4 GlpE family protein compare
BWI76_RS09730 +0.8 1.2 pyruvate formate lyase 1-activating protein compare
BWI76_RS10400 +0.8 1.4 hypothetical protein compare
BWI76_RS21075 +0.8 1.2 membrane protein compare
BWI76_RS16195 +0.8 1.2 hypothetical protein compare
BWI76_RS07745 +0.8 4.3 isochorismate synthase EntC compare
BWI76_RS14305 +0.8 1.9 metallophosphoesterase compare
BWI76_RS08120 +0.8 1.8 cobalt transporter compare
BWI76_RS23845 +0.8 1.0 ASCH domain-containing protein compare
BWI76_RS09515 +0.8 1.2 arginine ABC transporter substrate-binding protein compare
BWI76_RS05550 +0.8 3.4 fermentation/respiration switch protein compare
BWI76_RS07380 +0.8 1.6 hypothetical protein compare
BWI76_RS23595 +0.8 2.3 N-acetyltransferase compare
BWI76_RS12550 +0.8 1.8 hypothetical protein compare
BWI76_RS09390 +0.8 2.2 phage tail protein compare
BWI76_RS04855 +0.8 1.9 regulatory protein AmpE compare
BWI76_RS24025 +0.8 3.4 agmatinase compare
BWI76_RS20150 +0.8 0.8 NADH:ubiquinone oxidoreductase subunit J compare
BWI76_RS23480 +0.8 1.4 EAL domain-containing protein compare
BWI76_RS14390 +0.8 1.3 hypothetical protein compare
BWI76_RS14010 +0.8 1.6 SDR family oxidoreductase compare
BWI76_RS16500 +0.8 0.8 superoxide dismutase [Fe] compare
BWI76_RS14145 +0.8 2.4 dihydrolipoyl dehydrogenase compare
BWI76_RS19645 +0.8 3.0 galactose ABC transporter substrate-binding protein compare
BWI76_RS27175 +0.8 2.9 hypothetical protein compare
BWI76_RS04120 +0.7 1.6 metal-dependent hydrolase compare


Specific Phenotypes

For 17 genes in this experiment

For stress Paraquat dichloride in Klebsiella michiganensis M5al

For stress Paraquat dichloride across organisms